Anti-inflammatory Or Anti-irritant (e.g., Anti-arthritic, Etc.) Patents (Class 424/78.05)
  • Patent number: 6419936
    Abstract: A topical skin ointment for application onto the skin of individuals suffering from minor skin irritations such as dry chapped skin, minor cuts, and scrapes and abrasions. The topical skin ointment includes ingredients to reduce the discomfort associated with these types of skin irritations as well ingredients to promote the natural healing process.
    Type: Grant
    Filed: June 21, 2000
    Date of Patent: July 16, 2002
    Inventor: Adell J. Schmoyer
  • Patent number: 6395289
    Abstract: The invention discloses a mammalian teat dip for controlling mastitis, a method for preparing the composition and a method of treatment of mammals. The composition contains a film-forming polymer blend, at least one antimicrobial and a sodium bicarbonate buffering agent. The polymer blend contains a solvent-soluble, thermoplastic polyurethane and a hydrophilic poly(N-vinyl lactam). Upon application to mammalian skin, this composition leaves a long-lasting, water-resistant, residual, elastic film that treats and protects mammalian skin from infection.
    Type: Grant
    Filed: April 25, 2000
    Date of Patent: May 28, 2002
    Assignee: Hydromer, Inc.
    Inventors: Joseph Ehrhard, Michael Eknoian, Alfredo Vinci
  • Patent number: 6379686
    Abstract: A composition for treating a substrate to control dust mite populations thereon. The composition includes a fluoropolymer, a biocide, and an acaricide.
    Type: Grant
    Filed: January 12, 1999
    Date of Patent: April 30, 2002
    Assignee: MagiSeal Corporation
    Inventors: James T. Harris, Bernardus M. Tangelder
  • Patent number: 6375962
    Abstract: Skin protection agents such as topical compositions which can prevent the passage of toxic chemicals through the skin, such as barrier creams. Formulations may contain hexamethylene tetramine or derivatives or analogues thereof, which react with alkylating agents such as sulfur mustard, and which are suitable for formulation into topical compositions. The formulations additionally may contain perfluorinated polymeric compounds which are effective barrier compounds for a range of toxic chemicals.
    Type: Grant
    Filed: January 23, 2001
    Date of Patent: April 23, 2002
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland
    Inventors: John Jenner, Colin N Smith, Robert P Chilcott, Christopher D Lindsay
  • Patent number: 6365175
    Abstract: Edible compositions containing petroselinic acid are used for the preparation of food compositions or food supplements that are used as anti-inflammatory compositions that inhibit the production of metabolites of arachidonic acid and/or reduces the formation of intracellular adhesion molecules or as anti-aging compositions with a positive impact on wrinkling, sagging, photodamaged skin, dry skin, flaky skin and age spots.
    Type: Grant
    Filed: December 22, 1999
    Date of Patent: April 2, 2002
    Assignee: Unilever Patent Holdings
    Inventors: Simon Alaluf, Martin Richard Green, Jonathan Richard Powell, Julia Sarah Rogers, Allan Watkinson, Frederick William Cain, Heng Long Hu, Anthony Vincent Rawlings
  • Patent number: 6352686
    Abstract: This invention relates to a nail polish comprising one or more glucocorticoids useful in treating nails which show changes due to the syndrome of psoriasis.
    Type: Grant
    Filed: August 18, 1998
    Date of Patent: March 5, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Manfred Bohn, Karl Theodor Kraemer
  • Patent number: 6348479
    Abstract: This invention provides a milk lotion, cream or the like which does not undergo oil-water phase separation but remains stable for a long time and, in addition, has a good skin feel with good spreadability. It is a water-in-oil emulsifier composition comprising liquid oil basis, liquid oil component gelling agent, water and, as a water-in-oil type surfactant, polyglycerin fatty acid ester and/or polyoxyethylene hydrogenated castor oil.
    Type: Grant
    Filed: May 11, 2000
    Date of Patent: February 19, 2002
    Assignee: Fujisawa Pharmaceutical Co., Ltd.
    Inventors: Michio Mori, Tsuguo Yabuta, Osamu Matsuoka
  • Patent number: 6342213
    Abstract: A cyanoacrylate adhesive is applied to non-suturable, non-sterile wound surfaces to protect and/or treat such surfaces, to promote wound healing and to retard infection of the wound.
    Type: Grant
    Filed: April 22, 1994
    Date of Patent: January 29, 2002
    Assignee: MedLogic Global Corporation
    Inventors: Leonard V. Barley, Linda M. Barley, J. Royce Renfrow, Patrick J. Tighe
  • Patent number: 6322814
    Abstract: A process is claimed whereby an aqueous solution of agar, in which most (ideally all) 4-linked residues consist of 3,6-anhydro-L-galactose, is subjected to partial acid hydolysis and upon neutralization following the time appropriate for the chosen conditions, a low strength gel is obtained, from which, contrary to expectations, a polyagarobiose can be obtained by freeze-thawing and straining, thereby eliminating undesirable agaroid materials without the appropriate 3,6-anhydrogalactosyl content. The appropriate time of hydrolysis depends on initial gel strength, pH, counterion concentration and temperature. As an example, agar (gel strength 700 g/cm2, made to 1.86% solution) pH 3.25, counterion citrate (360 mg/L) at 96° C. requires 25 minutes to yield a material with an eventual gel stregth (1.5% solution) of 40 g/cm2. A stabilized product can be prepared by reducing terminal anhydrogalactosyl residues with sodium borohydride.
    Type: Grant
    Filed: November 29, 1999
    Date of Patent: November 27, 2001
    Inventor: Ian James Miller
  • Publication number: 20010043935
    Abstract: Processes for treatment of at least one condition chosen from seborrhoea of the skin and scalp, disorders associated with seborrhoea, and disorders associated with microorganisms of the genus Propionibacterium comprising applying to an area in need of said treatment at least one compound chosen from certain polyamino acid derivatives. Processes for the manufacture of a composition for treatment of at least one condition chosen from seborrhoea of the skin and scalp, disorders associated with seborrhoea, and disorders associated with microorganisms of the genus Propionibacterium, said process comprising including in said composition at least one certain polyamino acid derivative. Anti-seborrhoeic and anti-acne compositions comprising at least one certain polyamino acid derivative.
    Type: Application
    Filed: January 29, 2001
    Publication date: November 22, 2001
    Inventors: Michel Philippe, Sylvie Cupferman
  • Patent number: 6299902
    Abstract: A novel topical anesthetic preparation is characterized by improved transdermal absorption and efficacy. In a preferred embodiment, the topical preparation contains at least one local anesthetic agent and at least two melting point depressing agents. Also provided is a two-phase liquid composition that contains aqueous and oil phases, the oil phase having a relatively high concentration of a local anesthetic agent to enhance transdermal absorption and efficacy when incorporated into a topical anesthetic preparation. A preferred topical anesthetic preparation includes lidocaine or tetracaine, thymol or menthol, and ethyl alcohol or isopropyl alcohol. The preparation is expected to be safe and effective in obtaining transdermal anesthesia on intact skin and mucous membrane of adults, children, infants and newborns.
    Type: Grant
    Filed: July 19, 1999
    Date of Patent: October 9, 2001
    Assignee: The University of Georgia Research Foundation, Inc.
    Inventors: H. Won Jun, Lisheng Kang
  • Patent number: 6287601
    Abstract: Compositions and methods of the topical treatment of equine laminitis are disclosed. In particular, combinations of a fast acting nitric oxide (NO) donor, a sustained acting NO donor and an NSAID mixed in a lipid-based carrier are described. The application of such combinations to the affected areas, e.g., the hoofs and surrounding tissues, of an equine afflicted with laminitis provides relief from the debilitating effects of this painful, often life-threatening condition.
    Type: Grant
    Filed: June 16, 1999
    Date of Patent: September 11, 2001
    Inventor: Meri Charmyne Russell
  • Patent number: 6261544
    Abstract: A method for alleviating the symptoms of a cosmetic or dermatologic skin condition is described. An effective amount of a poly(hydroxy acid)/polymer conjugate in a pharmaceutically or cosmetically acceptable vehicle is provided. Topical compositions of the conjugates with another cosmetic or dermatological agent, and compounds of the conjugates having attached physiologically active functional groups, are also provided.
    Type: Grant
    Filed: February 15, 1999
    Date of Patent: July 17, 2001
    Assignee: Focal, Inc.
    Inventors: Arthur J. Coury, Luis Z. Avila, Chandrashekhar P. Pathak, Shikha P. Barman
  • Patent number: 6248341
    Abstract: The present invention relates to a method of inhibiting angiogenesis in mammalian tissue which comprises supplying to the tissue a composition comprising an effective amount of epigallocatechin-gallate, epicatechin gallate or a combination thereof. The method is particularly useful in the treatment of angiogenesis-related skin conditions in which the catechin is applied topically, such as the treatment of various skin cancers, psoriasis, spider veins or undereye circles.
    Type: Grant
    Filed: January 14, 2000
    Date of Patent: June 19, 2001
    Assignee: Color Access, Inc.
    Inventors: Jon Anderson, Mary Steidl Matsui
  • Patent number: 6242425
    Abstract: An object is to provide: novel quinolinone glycosides which are useful as medicines; processes for producing the quinolinone glycosides; intermediates for synthesis; and medicines, and particularly anti-allergic agents, which comprise the quinolinone glycoside as an active ingredient.
    Type: Grant
    Filed: January 14, 1999
    Date of Patent: June 5, 2001
    Assignee: Dainippon Ink and Chemicals, Inc.
    Inventors: Hidetsugu Takagaki, Shigenori Nakanishi, Nobuyuki Kimura, Shinobu Yamaguchi, Yasuo Aoki
  • Patent number: 6242509
    Abstract: An ester-terminated dimer acid-based polyamide may be blended with a solvent to form a gel. The solvent may be flammable, and a wick may be added to the resulting gel so as to form a candle. Depending on the composition, the candle may be formed into a free standing pillar, or may be better suited to being placed in a container. The solvent may be mineral oil. A solid coating may be placed around the candle, for advantages including to enhance the clarity and/or mechanical stability of the gelled body, and to eliminate the tendency of a gel to have an oily feel and to accept noticeable fingerprints. The ester-terminated dimer acid-based polyamide may also be combined with an active ingredient, such as a fragrance, colorant, insect-repellant, insecticide, bioactive ingredient or the like, to afford a delivery vehicle for the active ingredient.
    Type: Grant
    Filed: April 15, 1999
    Date of Patent: June 5, 2001
    Assignees: International Paper Company, Bush Boake Allen Inc.
    Inventors: Vivian Berger, Jochen Heydel, Virgil A. G. Williams, Charles R. Frihart, Ronald L. Gordon, Richard C. MacQueen, Mark S. Pavlin
  • Patent number: 6224885
    Abstract: The present invention relates to protection agents, in particular to topical compositions such as barrier creams which can prevent the passage of toxic chemicals and chemical warfare agents through the skin. Formulations contain hexamethylene tetramine derivatives or analogues thereof and perfluorinated polymeric compounds.
    Type: Grant
    Filed: December 7, 1998
    Date of Patent: May 1, 2001
    Assignee: The Secretary of State for Defence in Her Britannic Majesty's Government of the United Kingdom of Great Britain and Northern Ireland
    Inventors: John Jenner, Colin N Smith, Robert P Chilcott, Christopher D Lindsay
  • Patent number: 6214318
    Abstract: Aerosol compositions are provided that enhance the therapeutic action of ointments by producing, upon topical application thereof, a sustained cooling effect that provides fast relief form pain and itching as well as a tendency to shrink swollen, inflamed tissue. The compositions contain oils, thickening agents for the oils, and propellant. Aqueous solutions, therapeutic ingredients and various adjuvants may also be present. The specific propellant and the proportion used are selected to provide a deposit with a temperature of about −5° C. to about +5° C. In this temperature range, the deposit is cold enough for the required therapeutic effect, but not so cold as to cause pain or tissue damage. The choice and proportion of thickening agents used are selected to provide a deposit that does not flow or spread. Were the deposit to spread, it would present a large surface area from which propellant present in the deposit would evaporate rapidly.
    Type: Grant
    Filed: March 30, 1999
    Date of Patent: April 10, 2001
    Assignee: OMS Holdings LLC
    Inventors: Lloyd I. Osipow, Dorothea C. Marra, J. George Spitzer
  • Patent number: 6203812
    Abstract: The invention discloses a mammalian teat dip for controlling mastitis, a method for preparing the composition and a method of treatment of mammals. The composition contains a film-forming polymer blend and at least one antimicrobial. The polymer blend contains a solvent-soluble, thermoplastic polyurethane and a hydrophilic poly(N-vinyl lactam). Upon application to mammalian skin, this composition leaves a long-lasting, water-resistant, residual, elastic film which treats and protects mammalian skin from infection.
    Type: Grant
    Filed: June 29, 1998
    Date of Patent: March 20, 2001
    Assignee: Hydromer, Inc.
    Inventors: Joseph Ehrhard, Michael Eknoian
  • Patent number: 6187324
    Abstract: A cosmetic composition comprising at least one of Kumazasa extract and medicinal carbon. The cosmetic composition exhibits an excellent deodorizing effect and antibacterial effect, and is applied to toilet soap, facial cleansing cream, shampoo, rinse, etc.
    Type: Grant
    Filed: June 21, 1999
    Date of Patent: February 13, 2001
    Assignee: Kabushiki Kaisha Ogi Kogei
    Inventors: Takehiko Ogi, Tadahiko Takei
  • Patent number: 6180601
    Abstract: The invention relates to freeze-dried soft, flexible and continous matrix of low-molecular weight hyaluronic acid or salt thereof, in which the molecular weight of the hyaluronic acid is preferably between 50 000 and 200 000 Da, containing at least one peptide or protein. It also relates to a pharmaceutical composition in the form of a layer which is characterised by this freeze-dried low-molecular weight hyaluronic acid containing at least one peptide or protein. The drug is preferably chosen from at least one of GH, IGF-I, IGF-II and/or EGF and could be mixtured with an antibiotic agent. The process for the manufacture of this matrix and the use of the pharmaceutical composition for the manufacturing of a drug for wound healing is claimed. The invention discloses a method for accurately obtaining a predetermined dosage of a topically administerable drug which is characterised by freeze-drying a water solution of low-molecular weight hyaluronic acid and the peptide or protein to form a layer.
    Type: Grant
    Filed: June 18, 1996
    Date of Patent: January 30, 2001
    Assignee: Pharmacia AB
    Inventor: Gustaf Jederström