Including Titration Or Ph Determination Patents (Class 436/163)
  • Patent number: 11951971
    Abstract: In one aspect, a system for monitoring a level of hydraulic fluid in an agricultural sprayer includes a drive system, a hydraulic fluid system, and a fill level sensor. The system also includes a computing system communicatively coupled to both the drive system and the fill level sensor. The computing system is configured to monitor the level of hydraulic fluid within the hydraulic fluid reservoir based on data received from the fill level sensor. The computing system is further configured to detect a leak condition in the hydraulic fluid system based at least in part on the monitored level of the hydraulic fluid within the hydraulic fluid reservoir and control an operation of the drive system to reduce the ground speed of the agricultural sprayer in response to detecting the leak condition.
    Type: Grant
    Filed: May 25, 2021
    Date of Patent: April 9, 2024
    Assignee: CNH Industrial America LLC
    Inventors: David Hafvenstein, Timothy Patrick Croydon, John Patrick Greifzu
  • Patent number: 11906452
    Abstract: The present disclosure relates to a pH-sensor for determining and/or monitoring a pH value of a medium, having a sensor unit with a wall in contact with the medium, and at least one pH-sensitive material, which has at least one spin state that changes as a function of a pH value. The at least one pH-sensitive material is arranged in or on a region of the wall in such a way that the at least one spin state is subjected to a change in the pH value of the medium. The pH-sensor also includes a spin-sensitive unit, which is configured to detect a variable associated with the at least one spin state, wherein the spin-sensitive unit is arranged in an environment of the at least one pH-sensitive material such that the spin-sensitive unit is subjected to a change in the spin state of the at least one pH-sensitive material.
    Type: Grant
    Filed: May 23, 2022
    Date of Patent: February 20, 2024
    Assignee: Endress+Hauser Conducta GmbH+Co. KG
    Inventors: Thomas Wilhelm, Mohammad Sadegh Ebrahimi, Raphael Kuhnen, Matthäus Speck
  • Patent number: 11860084
    Abstract: The present invention relates to an analytical method that includes providing a sample potentially containing a chiral analyte that can exist in stereoisomeric forms, and providing a probe selected from the group consisting of metal salts. The sample is contacted with the probe under conditions that permit coordination of the probe to the analyte, if present in the sample; and, based on any coordination that occurs, the absolute configuration of the analyte in the sample, and/or the concentration of the analyte in the sample, and/or the enantiomeric composition of the analyte in the sample is/are determined.
    Type: Grant
    Filed: September 11, 2019
    Date of Patent: January 2, 2024
    Assignee: GEORGETOWN UNIVERSITY
    Inventors: Christian Wolf, Zeus A. O. De Los Santos, Ciaran Lynch
  • Patent number: 11846604
    Abstract: Ion sensing device includes a field-effect transistor including a bottom gate and a top gate, a reference electrode, and a driver circuit configured to measure concentration of ions in a sample solution into which the reference electrode and the top gate are immersed. The driver circuit includes a constant current source configured to supply a drain of the field-effect transistor with a constant current, and a voltage follower configured to receive a potential of the drain. The driver circuit is configured to supply the reference electrode with a constant reference potential, apply a constant voltage across an output of the voltage follower and the bottom gate, and output an output potential of the voltage follower.
    Type: Grant
    Filed: November 17, 2020
    Date of Patent: December 19, 2023
    Assignee: TIANMA JAPAN, LTD.
    Inventor: Hiroyuki Sekine
  • Patent number: 11796543
    Abstract: A system for detecting COVID-19 infection, including a colorimetric sensor, an image-capturing device, and a processing unit connected to the image-capturing device. The colorimetric sensor includes an injection zone and a detection zone patterned on a paper, where the injection zone covers the detection zone by folding the paper. The injection zone is configured to inject a saliva sample acquired from a person thereon. The detection zone includes an array of chemical receptors configured to interact with the injected saliva penetrating into the detection zone. The processing unit is configured to perform a method of capturing a first image from the detection zone before injection of the saliva sample, capturing a second image from the detection zone after injection of the saliva sample, and detecting COVID-19 infection status of the person by analyzing color changes of the array of chemical receptors in the second image respective to the first image.
    Type: Grant
    Filed: June 27, 2022
    Date of Patent: October 24, 2023
    Assignee: FARIN BEHBOOD TASHKHIS COMPANY
    Inventors: Hasan Bagheri, Mohammad Mahdi Bordbar, Hosein Khoshsafar, Pegah Hashemi, Mostafa Ghanei
  • Patent number: 11607681
    Abstract: According to an example aspect of the present invention, there is provided a liquid handling device comprising: means for harvesting energy; energy storage arranged for storing the harvested energy in the liquid handling device; and an electronic component connected to the energy storage and configured to use the energy storage as a power source.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: March 21, 2023
    Assignee: Sartorius Biohit Liquid Handling Oy
    Inventors: Sami Alt, Janne Leinonen
  • Patent number: 11491236
    Abstract: The present disclosure is directed at an antibody conjugate having an antibody and a tag, wherein one or more element(s) present in the antibody exhibit an isotope ratio which differs from the naturally occurring isotope ratio of the one or more element(s), wherein the amount of the isotope which is less-common in nature, is increased to at least 4% of the atoms of the respective element in the antibody, as well as uses thereof.
    Type: Grant
    Filed: April 20, 2020
    Date of Patent: November 8, 2022
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Harmut Duefel, Uwe Kobold, Andreas Leinenbach
  • Patent number: 11371919
    Abstract: The present invention relates to the preparation of liquid mixtures, and more particularly to the preparation of a liquid mixture, such as a buffer, wherein the conductivity of the liquid mixture is measured and the pH indirectly determined if the buffer concentration is known. Another object of the present invention is to provide a method of preparing a liquid mixture with a predetermined pH value by using conductivity as feedback control parameter.
    Type: Grant
    Filed: February 28, 2020
    Date of Patent: June 28, 2022
    Assignee: CYTIVA SWEDEN AB
    Inventors: Enrique Napoleon Carredano, Elenor Strandberg
  • Patent number: 11280725
    Abstract: A measurement device includes: a measurement unit which is configured to measure an absorption spectrum of a dispersion liquid in which nanocarbons are dispersed; a separation unit which is configured to separate an absorption spectrum of a dispersant from the absorption spectrum of the dispersion liquid; and a calculation unit which is configured to calculate a concentration of the dispersant from the absorption spectrum of the dispersant.
    Type: Grant
    Filed: September 29, 2017
    Date of Patent: March 22, 2022
    Assignee: NEC CORPORATION
    Inventor: Fumiyuki Nihey
  • Patent number: 11193259
    Abstract: A water delivery system includes a mixing valve operable for delivering a water flow of adjustable temperature from a water source to a dispensing device downstream from the mixing valve; a thermochromic thermal indicator, fluidly coupled between the mixing valve and the dispensing device, that provides a visible indication of the water flow having achieved a predetermined temperature; and a diverter valve, fluidly coupled between the mixing valve and the dispensing device, and operable to direct the water flow selectively either to the dispensing device or back to the water source. The thermal indicator may be a thermochromic PVC conduit, or it may be a fitting having an inlet, an outlet, a thermochromic PVC element therebetween, and a barrier located between the inlet and the outlet so as to define a flow path that includes an interior surface of the thermochromic element.
    Type: Grant
    Filed: August 27, 2019
    Date of Patent: December 7, 2021
    Assignee: AQUA VIEW INC.
    Inventor: Gus Searcy
  • Patent number: 11193889
    Abstract: A compact and miniaturized Fourier transform photoluminescence (PL) spectrometer is provided comprising five functional modules, which are all mounted on a same baseplate: (i) a sample placement module for positioning and spatially adjusting the sample to be tested, which includes a 3-axis stage (10) and a position mark (11) for the expected front surface of the sample being tested. The stage is employed for positioning the sample directly or a low-temperature optical cryostat that contains the sample (said sample and cryostat being not parts of the spectrometer), the position mark indicates the pre-aligned position for the projection of the sample's front surface in the horizontal plane; (ii) a built-in pump light source module for generating PL signal, which includes two lasers (20) and (21) with different laser wavelengths, the lasers' output can be selected on request in the wavelength range from ultraviolet to near-infrared.
    Type: Grant
    Filed: July 27, 2020
    Date of Patent: December 7, 2021
    Assignee: INSA OPTICS TECHNOLOGY (SHANGHAI) LTD.
    Inventors: Jihua Li, Jun Shao
  • Patent number: 11155699
    Abstract: Provided are nanocellulose composite and preparation method thereof. The method comprises preparing cellulose nanofiber, mixing the cellulose nanofiber with a silica precursor in a solvent to attach silica particles to the surface of the cellulose nanofiber, or to form a silica coating layer on the surface of the cellulose nanofiber, and mixing the cellulose nanofiber with the silica particles or the silica coating layer with a polymer. According to the present invention, by using surface vitrification-treated nano cellulose, nanocellulose polymer composites that exhibits high mechanical properties such as impact resistance as well as excellent heat resistance can be prepared.
    Type: Grant
    Filed: April 12, 2018
    Date of Patent: October 26, 2021
    Assignee: INDUSTRY-ACADEMIA COOPERATION GROUP OF SEJONG UNIVERSITY
    Inventors: Young Soo Seo, Sang Yul Park, Hyo Sun Kim, Song Hee Lee
  • Patent number: 11125738
    Abstract: A system includes an optical measurement unit that measures an optical property of a whole blood sample deposited on a surface of a substrate, an ion source that causes ions derived from the whole blood sample, including ions formed from an analyte of interest present in the whole blood sample, to be emitted from the substrate, a mass analyzer that receives the ions emitted from the substrate and measures an abundance of at least one ion species corresponding to the analyte of interest, and at least one computing device that determines, based on the measured optical property, a hematocrit of the whole blood sample, and determines, based on the determined hematocrit of the whole blood sample and the measured abundance of the at least one ion species, a concentration of the analyte of interest per unit volume of blood plasma.
    Type: Grant
    Filed: November 6, 2018
    Date of Patent: September 21, 2021
    Assignee: THERMO FINNIGAN LLC
    Inventors: John Glazier, Jae C. Schwartz, Berg A. Tehlirian
  • Patent number: 11116212
    Abstract: Compositions and methods for controlling and/or repelling bedbugs are provided. The compositions comprise one or more compounds having bedbug repellant activity. Such compounds may be, for example, naturally occurring semiochemicals or structural or functional analogs of naturally occurring semiochemicals. Exemplary compounds are compounds of general formula (I).
    Type: Grant
    Filed: March 29, 2012
    Date of Patent: September 14, 2021
    Assignee: SemiosBio Technologies Inc.
    Inventor: Michael Gilbert
  • Patent number: 11045787
    Abstract: Composite granules that contain a binder and a polymeric sorbent material for capturing aldehydes such as formaldehyde are provided. Additionally, methods of making the composite granules, methods of using the composite granules to capture aldehydes, and compositions formed by reacting the composite granules with aldehydes are provided. The polymeric sorbent material included in the composite granules is a reaction product of a divinylbenzene/maleic anhydride precursor polymeric material with a nitrogen-containing compound. This reaction results in the formation of nitrogen-containing groups that are covalently attached to the polymeric sorbent. Aldehydes can react with the nitrogen-containing groups.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: June 29, 2021
    Assignee: 3M Innovative Properties Company
    Inventors: Michael W. Kobe, Michael S. Wendland
  • Patent number: 11014070
    Abstract: Composite granules that contain a binder and polymeric sorbent materials for capturing reactive gases are provided. Additionally, methods of making the composite granules and methods of using the composite granules to capture reactive gases, and compositions formed by exposing the composite granules to reactive gases are provided. The polymeric sorbent material included in the composite granules is a reaction product of a divinylbenzene/maleic anhydride precursor polymeric material with a nitrogen-containing compound. This reaction results in the formation of nitrogen-containing groups that are covalently attached to the polymeric sorbent. The reactive gases undergo an acid-base reaction with the nitrogen-containing groups.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: May 25, 2021
    Assignee: 3M Innovative Properties Company
    Inventors: Michael W. Kobe, Michael S. Wendland
  • Patent number: 10967358
    Abstract: Composite granules that contain a binder and a polymeric sorbent material for capturing aldehydes such as formaldehyde are provided. Additionally, methods of making the composite granules, methods of using the composite granules to capture aldehydes, and compositions formed by reacting the composite granules with aldehydes are provided. The polymeric sorbent material included in the composite granules is a reaction product of a divinylbenzene/maleic anhydride precursor polymeric material with a nitrogen-containing compound. This reaction results in the formation of nitrogen-containing groups that are covalently attached to the polymeric sorbent. Aldehydes can react with the nitrogen-containing groups.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: April 6, 2021
    Assignee: 3M Innovative Properties Company
    Inventors: Michael W. Kobe, Michael S. Wendland
  • Patent number: 10745540
    Abstract: Selectively-releasable colorant compositions that allow a controllable release of colorant molecules from resin in response to one or more specific environmental stimuli. The selectively-releasable colorant composition may comprise resin particles having colorant molecules reversibly bound thereto. The compositions of the present disclosure may also provide precise and uniform control of free colorant content in an environment and/or protection of the immobilized (i.e., unreleased) colorant from compromising environmental chemistries. The present disclosure also relates to methods of preparing and methods of using the compositions described herein.
    Type: Grant
    Filed: August 1, 2017
    Date of Patent: August 18, 2020
    Assignee: CAREFUSION 2200, INC.
    Inventors: Brandon Borowski, Nathan Sieracki
  • Patent number: 10670588
    Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: June 2, 2020
    Assignee: Theranos IP Company, LLC
    Inventors: Tammy Burd, Ian Gibbons, Elizabeth A. Holmes, Gary Frenzel, Anthony Joseph Nugent
  • Patent number: 10647854
    Abstract: A method of obtaining a leuco polymer, the method comprising the step of reacting a reactive leuco compound with a polymer to form the leuco polymer. The reactive leuco compound comprises at least one leuco moiety and at least one nucleophilic group. The polymer comprises at least one group capable of reacting with said nucleophilic group. The said leuco moiety has a maximum molar extinction coefficient at a wavelength in the range 400 to 750 nm of less than 1000 M?1 cm?1. Laundry care compositions comprising the leuco polymer and methods of treating textiles with such laundry care compositions.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: May 12, 2020
    Assignee: Milliken & Company
    Inventors: Sanjeev K. Dey, Haihu Qin, Gregory S. Miracle
  • Patent number: 10641662
    Abstract: The present invention relates to a method for estimating a geothermal gradient and an apparatus for estimating a geothermal gradient, and provides a method for estimating a geothermal gradient, the method comprising the steps of: calculating, at each of a plurality of points, a seismic wave crustal attenuation characteristic parameter of a seismic wave measured on the basis of the measured seismic wave information, with respect to the plurality of points; deriving an artificial neural network relational formula on the basis of the seismic wave crustal attenuation characteristic parameter; and calculating a geothermal gradient of an area of interest excluding the plurality of points on the basis of the artificial neural network relational formula, such that the geothermal gradient is estimated at a low cost by using a highly reliable method.
    Type: Grant
    Filed: August 24, 2016
    Date of Patent: May 5, 2020
    Assignee: Korea Electric Power Corporation
    Inventors: Kwan Hee Yun, Jung Tak Shim, Eun Ju Jung
  • Patent number: 10598654
    Abstract: The present invention provides devices and systems for use at the point of care. The methods devices of the invention are directed toward automatic detection of analytes in a bodily fluid. The components of the device are modular to allow for flexibility and robustness of use with the disclosed methods for a variety of medical applications.
    Type: Grant
    Filed: July 22, 2016
    Date of Patent: March 24, 2020
    Assignee: Theranos IP Company, LLC
    Inventors: Tammy Burd, Ian Gibbons, Elizabeth A. Holmes, Gary Frenzel, Anthony Joseph Nugent
  • Patent number: 10590275
    Abstract: A method of obtaining a leuco polymer, the method comprising the step of reacting a compound with a polymer to form the leuco polymer. The compound includes at least one leuco moiety and at least one electrophilic group. The polymer is comprised of co-monomers of an aryl dicarboxylate, an oxyalkyleneoxy and an oxypolyalkyleneoxy and the polymer comprises at least one moiety selected from the group consisting of hydroxy, sulfhydryl, primary amine and secondary amine. Laundry care compositions comprising the leuco polymer and methods of treating textiles with such laundry care compositions.
    Type: Grant
    Filed: November 1, 2017
    Date of Patent: March 17, 2020
    Assignee: Milliken & Company
    Inventors: Sanjeev K. Dey, Wesley A. Freund, Gregory S. Miracle
  • Patent number: 10487297
    Abstract: Provided are antimicrobial compositions that include a hydrogen peroxide generator, a peracid catalyst, a sugar acid lactone selected from among a gluconolactone, a galactonolactone, a mannonolactone, a gulonolactone and a combination thereof in an amount from about 10 wt % to about 60 wt %, an acetate, and a carboxylic acid, where the ratio between the hydrogen peroxide generator and the peracetic acid catalyst is from about 1.5:1 to about 3:1 respectively. The compositions have increased shelf life and storage stability. The antimicrobial compositions can be formulated into a disinfection solution. Also provided are methods of disinfecting a surface that include applying the disinfecting solution to a surface, resulting in the destruction of a microbe on the surface.
    Type: Grant
    Filed: June 1, 2017
    Date of Patent: November 26, 2019
    Assignee: CHEMLINK LABORATORIES, LLC
    Inventor: Ryan Giffin Moore
  • Patent number: 10317386
    Abstract: A method of measuring nitrate concentration in an aqueous sample includes mixing the aqueous sample with a water-soluble thioether chosen to reduce nitrate in the aqueous sample to nitrite in the presence of a water soluble catalyst, and a water soluble reagent system adapted to interact with nitrite to generate a color; measuring color generation, and correlating the color generation to nitrate concentration.
    Type: Grant
    Filed: July 29, 2016
    Date of Patent: June 11, 2019
    Assignee: HACH COMPANY
    Inventors: Darren Kent MacFarland, Angella Nicholle Greenawalt
  • Patent number: 10274454
    Abstract: To measure target component concentration in a liquid with higher accuracy without any dedicated apparatus or skill, a method is adapted to include: receiving a successive measurement value obtained by performing successive measurement of the target component concentration with use of a first measurement device immersed in the liquid; receiving a batch measurement value obtained by, with use of a second measurement device, performing batch measurement of the target component concentration in a part sampled from the liquid; and, when the batch measurement value is received, successively calculating a correlation value indicating the correlation between multiple successive measurement values and multiple batch measurement values respectively obtained in mutually corresponding multiple times of successive measurement and multiple times of batch measurement.
    Type: Grant
    Filed: February 14, 2017
    Date of Patent: April 30, 2019
    Assignees: HORIBA, LTD., HORIBA ADVANCED TECHNO, CO., LTD.
    Inventors: Akio Nakayama, Rumiko Furuya, Yuichi Ito, Akio Ishii, Yuji Gyoten, Yoshitake Ando, Hiroaki Murakami
  • Patent number: 10238766
    Abstract: The present invention relates to the field of medical diagnostics and more specifically, to identification of amniotic fluid.
    Type: Grant
    Filed: June 30, 2015
    Date of Patent: March 26, 2019
    Assignee: Common Sense Ltd.
    Inventors: Yifat Hershcovitz-Fundoiano, Vered Pardo-Yissar, Hadar Kessary Shoham
  • Patent number: 10234440
    Abstract: A method and system for testing soil includes wetting a selected soil sample to obtain a soil solution and measuring an initial pH of the soil solution. A buffer solution is then applied to the soil solution to displace alkaline anions from soil colloids of the soil solution with a displacement agent and to neutralize the alkaline anions with a neutralization agent in a buffer having a buffer pH of between 4.38 and 4.42. A resultant pH of the soil solution is then measured. A target pH for the soil sample is selected, and using mathematical relationships of the disclosure, an acidic amendment recommendation is obtained as a function of the initial pH, the resultant pH, and the target pH.
    Type: Grant
    Filed: October 30, 2015
    Date of Patent: March 19, 2019
    Inventor: Gobena Huluka
  • Patent number: 9700888
    Abstract: Disclosed is a microfluidic cartridge that can perform highly accurate lab quality DNA tests and other amplification based tests at the point of care. The cartridge may have slanted channels that angle downward from the inlet well, where the sample is deposited, to the reaction well, where the sample will flow down to and initiate the reaction. In some examples, the cartridge may be fabricated from specific materials that enhance passive flow through the channels. Additionally, the reaction wells have an access port that allows ventilation to the reaction wells that enhances the flow of the sample from the inlet to the reaction well. The access ports allow convenient access for depositing the reaction mixture into the reaction wells after the cartridge is fabricated.
    Type: Grant
    Filed: April 13, 2016
    Date of Patent: July 11, 2017
    Assignee: IPMD INC.
    Inventors: Min Lee, Seok Yong Moon, Matthew Lee, Rimma Ten, Nick Huntington, Nupur Raychaudhuri, Phillip Scott Alexander, Laurence Bianchini
  • Patent number: 9526803
    Abstract: Described herein is a diagnostic chewing gum for identifying the presence of pathogens detectable via the mouth, in particular pathogens residing in nasal, oropharyngeal, laryngeal, oesophageal, ocular and/or pulmonal tissue of a user, more particularly pathogens selected from among a virus, bacterium, protozoa, prion, fungus or a combination thereof. The inventive diagnostic chewing gum includes a base material or particles (3) embedded and/or attached to the base material and an element (1, 5-7), like e.g. a releasable flavor molecule, attached to the base material and/or the particles, for the generation of a change in the chewing gum directly detectable by the user, wherein the element (1, 5-7) generates the change upon direct or indirect contact with a marker (4) which is released by the pathogens, or, in case of a virus or prion, by the cellular structure hosting it.
    Type: Grant
    Filed: March 8, 2013
    Date of Patent: December 27, 2016
    Assignee: Julius-Maximilians-Universitaet Wuerzburg
    Inventors: Lorenz Meinel, Matthias Schnabelrauch, Falko Schlottig
  • Patent number: 9465035
    Abstract: A nanodiamond particle including an NV center having ODMR intensity enhanced, of which surface is modified with a functional group containing a heteroatom, is provided. This nanodiamond particle as being chemically modified can serve for a fluorescent molecular probe which can be made use of in a biological system. By tracking a rotational motion of the NV center included in this fluorescent molecular probe, structural change of a protein can be analyzed in real time. The functional group containing a heteroatom can be at least any functional group of a hydroxyl group and a hydroxyalkyl group, or a carboxyl group.
    Type: Grant
    Filed: October 10, 2013
    Date of Patent: October 11, 2016
    Assignee: Japan Science and Technology Agency
    Inventors: Masahiro Shirakawa, Shingo Sotoma, Ryuji Igarashi, Yoshie Harada
  • Patent number: 9347922
    Abstract: Method for analyzing the alkalinity conditions in aqueous liquids, comprising: sampling a known amount of the aqueous liquid and placing it in a container of known volume, measuring pH in the sampled liquid and pressure in the container, adding a known amount of CO2 to the sampled liquid, and measuring pH in the sampled liquid and the pressure in the container, and finally calculating the total alkalinity based on the values from the performed measurements. An apparatus for conducting the method is also described as well as a method for controlling chemistry of a glycol containing liquid in a system for recovery of glycol.
    Type: Grant
    Filed: May 11, 2012
    Date of Patent: May 24, 2016
    Assignee: Institutt for Energiteknikk
    Inventors: Arne Dugstad, Marion Seiersten
  • Patent number: 9182353
    Abstract: Described is a lab-on-a-chip device and a method employing a lab-on-a-chip device for determining the concentration of species present in water.
    Type: Grant
    Filed: July 21, 2011
    Date of Patent: November 10, 2015
    Assignee: Hach Company
    Inventors: Corey Alan Salzer, Vishnu Vardhanan Rajasekharan, Isabel Nicola Huenig, Rainer Froemel, Markus Lenhard, Rolf Dieter Uthemann, Aria Farjam
  • Patent number: 9040307
    Abstract: Fluorescent pH detector and methods for measuring pH using the fluorescent pH detector.
    Type: Grant
    Filed: May 29, 2012
    Date of Patent: May 26, 2015
    Assignee: Blood Cell Storage, Inc.
    Inventors: Michael W. Reed, Steven J. Geelhood, Robert O. Dempcy
  • Publication number: 20150111200
    Abstract: The present teachings provide for systems, and components thereof, for detecting and/or analyzing light. These systems can include, among others, optical reference standards utilizing luminophores, such as nanocrystals, for calibrating, validating, and/or monitoring light-detection systems, before, during, and/or after sample analysis.
    Type: Application
    Filed: September 29, 2014
    Publication date: April 23, 2015
    Inventors: J. Michael PHILLIPS, Kevin S. Bodner, Aldrich N. K. Lau, Mark F. Oldham, Donald R. Sandell, David H. Tracy, Steven J. Boege
  • Patent number: 8980636
    Abstract: A system and method for performing automated titrations. An automatic titrator utilizes control devices and sensors adapted for various chemical reactions to perform titrations and determine the content of a desired component of a solution. Batch and continuous mode titrations are possible. Titrant is added to a sample either in varying amounts or rates and a titration endpoint is observed via sensors. Control devices detect when the titration endpoint occurs and calculates the desired content. Various reactions within the solution may be suppressed in order to titrate isolated components individually.
    Type: Grant
    Filed: March 15, 2013
    Date of Patent: March 17, 2015
    Assignee: Ecolab USA Inc.
    Inventors: John Wilhelm Bolduc, Blake Roberts Otting, Paul R. Kraus, Robert Ryther
  • Publication number: 20150064741
    Abstract: A wear-indicating metalworking fluid is provided that includes a lubricant base; and a wear-indicating agent. A method of determining wear in a metalworking fluid includes providing wear-indicating metalworking fluid that contains a lubricant base and a wear indicating agent; and observing the visual appearance of the metalworking fluid. A change in visual appearance of the metalworking fluid when compared to an unused metalworking fluid indicates wear of the metalworking fluid.
    Type: Application
    Filed: August 22, 2014
    Publication date: March 5, 2015
    Inventors: Emily J. Gibbons, Steven M. Badger, II, Leroy N. Hitchcock, Jacob F. Harkey
  • Publication number: 20150064732
    Abstract: An analytical test cartridge is provided. The analytical test cartridge can be used for medical analyses of liquid samples removed from a patient, for example blood. The analytical test cartridge is configured to provide for titration experiments. An example of a titration experiment that can be performed with the arrangement, is titration of heparin with protamine. Methods of assembly and use are provided.
    Type: Application
    Filed: February 28, 2014
    Publication date: March 5, 2015
    Inventor: Kee Van Sin
  • Patent number: 8969094
    Abstract: The present invention relates to a method for the validation of a non-particulate ion exchange adsorber and a kit for the validation of a non-particulate ion exchange adsorber.
    Type: Grant
    Filed: November 10, 2010
    Date of Patent: March 3, 2015
    Assignee: Sartorius Stedim Biotech GmbH
    Inventors: Wolfgang Demmer, Rene Faber, Hans-Heinrich Hoerl, Axel Thiefes
  • Publication number: 20150044776
    Abstract: Provided herein are fluorescent sensor agents, and methods of use and manufacture thereof. In particular, sensor agents are provided that exhibit a detectable change in fluorescence (e.g., fluorescence intensity) upon alteration of the pH of the surrounding environment (e.g., upon moving from one pH environment to another).
    Type: Application
    Filed: March 8, 2013
    Publication date: February 12, 2015
    Applicant: PROMEGA CORPORATION
    Inventors: Mei Cong, Cesear Corona, Mark G. McDougall, Chad Zimprich
  • Patent number: 8945936
    Abstract: In one aspect of the invention, a method includes determining an amount of carbon dioxide (CO2) in dialysate flowing through a dialysis system using a CO2 sensor associated with the dialysis system, determining, using a pH sensor associated with the dialysis system, a pH level of the dialysate, and calculating a level of bicarbonate in the dialysate based at least in part on the determined amount of CO2 measured in the gas and the determined pH level of the dialysate.
    Type: Grant
    Filed: April 6, 2011
    Date of Patent: February 3, 2015
    Assignee: Fresenius Medical Care Holdings, Inc.
    Inventors: Stephen R. Ash, Thomas A. Sullivan, David Carr, Michael James Beiriger
  • Publication number: 20150024508
    Abstract: A pH sensing apparatus includes an ion-sensing cell that includes a first half-cell including a first Ion-Sensitive Field Effect Transistor (ISFET) exposed to a surrounding solution; and a second reference half-cell exposed to the surrounding solution. The pH sensing apparatus further includes a pressure sensitivity compensation loop including a Non Ion-Sensitive Field Effect Transistor (NISFET). The pH sensing apparatus is configured to compensate for at least one of pressure and physical stresses using signals from the ion-sensing cell and feedback from the pressure sensitivity compensation loop. The pH sensing cell further includes a processing device configured to calculate a final pH reading compensated to minimize the at least one of pressure and physical stresses.
    Type: Application
    Filed: July 22, 2013
    Publication date: January 22, 2015
    Inventors: Donald Horkheimer, David S. Willits
  • Publication number: 20150024509
    Abstract: There is provided a method and device for measuring an ion concentration of a sample. The method comprises exposing a chemical sensor to the sample to provide an electrical output signal 5 representing said ion concentration and controlling a titrator exposed to the sample to release or absorb a quantity of ions to the sample. The method may use feedback means comprising Pulse Width Modulation control to drive the titrator such that the sample maintains a stable ion concentration.
    Type: Application
    Filed: March 6, 2012
    Publication date: January 22, 2015
    Applicant: DNA ELECTRONICS LTD.
    Inventors: Christofer Toumazou, Yan Liu
  • Publication number: 20150011010
    Abstract: The invention is related to an optode for determining chemical parameters of a sample wherein the optode consists of a polymer matrix consisting of sulfonated polyether ether ketone (SPEEK) in which a sensor dye is immobilized or more than one sensor dye is immobilized, wherein at least one of the immobilized sensor dyes is pH-sensitive. In addition, the present invention also concerns a method for determining the pH of a sample in which the invention-related optode is used.
    Type: Application
    Filed: January 18, 2013
    Publication date: January 8, 2015
    Inventors: Doerte Steinbrueck, Elmar Schmaelzlin, Hans-Gerd Loehmannsroeben
  • Patent number: 8921113
    Abstract: A buffer kit includes a first eluent and second eluent. The first eluent solution includes at least four buffer salts where at least three of the four buffer salts are a monovalent buffer salt, have a net negative charge or a net neutral zwitterionic charge, and include a sulfonate group and an amine. The second eluent solution includes at least four buffer salts where at least three of the four buffer salts are a monovalent buffer salt, have a net negative charge or a net neutral zwitterionic charge, and include a sulfonate group and an amine. The first eluent solution has a first pH and the second eluent solution has a second pH where the first pH and second pH are different values. The buffer kit provides a linear pH gradient that forms an approximately straight line from at least the first pH to the second pH.
    Type: Grant
    Filed: December 21, 2012
    Date of Patent: December 30, 2014
    Assignee: Dionex Corporation
    Inventors: Shanhua Lin, Christopher A. Pohl
  • Publication number: 20140356974
    Abstract: A pH detectable coating. The pH detectable coating includes a pH insensitive fluorescent dye and a pH sensitive fluorescent dye. The pH insensitive fluorescent dye and the pH sensitive fluorescent dye are attached to a surface. The ratio of the fluorescent intensity of the pH insensitive fluorescent dye to the fluorescent intensity of the pH sensitive fluorescent dye varies according to the pH of an environment into which the surface is placed.
    Type: Application
    Filed: May 30, 2013
    Publication date: December 4, 2014
    Inventors: Wen-Jing Hu, Liping Tang
  • Patent number: 8900875
    Abstract: A method for assessing a corrosion inhibitor in a coolant, comprises providing a test kit comprising a first chamber containing an acid buffer and a solvent immiscible therein and a second chamber containing an indicator, the second chamber being in fluid communication with the first chamber and being configured such that retraction of the second chamber draws fluid into the first chamber and advancement forces fluid into the second chamber; drawing a coolant sample into the first chamber; contacting the coolant sample with the acid buffer and solvent in the first chamber and extracting the corrosion inhibitor into the solvent; allowing the solvent and buffer to separate in the first chamber; forcing a portion of the separated solvent into the second chamber; contacting the separated solvent with the indicator in the second chamber, and obtaining a visual indication of the presence of corrosion inhibitor in the coolant sample.
    Type: Grant
    Filed: December 14, 2009
    Date of Patent: December 2, 2014
    Assignee: Shell Oil Company
    Inventors: Abraham Robert De Kraker, Liliana Minevski, Tze Lee Phang
  • Publication number: 20140349326
    Abstract: Apparatus and methods are provided for analyzing a medical condition of a user. The apparatus may include a user interface configured to receive user identification information inputted by the user, an analyzer, and a processor all disposed within a common housing. The analyzer is configured to receive a biological specimen from the user and to analyze the biological specimen to generate analysis information. The processor is configured to store and forward the analysis information and to receive prescription information. The apparatus may include a communication unit configured to transmit the user identification information and the analysis information to a doctor at a remote location for review and to receive the prescription information from the doctor. The apparatus then may dispense the prescribed medication or print a medication prescription.
    Type: Application
    Filed: February 6, 2013
    Publication date: November 27, 2014
    Inventor: Michael INGBER
  • Publication number: 20140329331
    Abstract: The present invention relates to a novel cyanne derivative having a meso-reaction functional group in a polymethine chain, and a preparation method thereof, and the cyanine derivative having the reaction functional group substituted at the meso site may be suitable for mass production thanks to a very simple synthesis method, have a very fast reaction rate because while a related art reagent for detection of nerve agents undergoes two steps of reactions, the cyanine derivative of the present invention undergoes only one step of reaction, have very excellent sensitivity, and be useful as an acid pH-activated ratiometric NIR probe because it is able to be activated in an acidic pH and is usable in an aqueous environment.
    Type: Application
    Filed: January 7, 2013
    Publication date: November 6, 2014
    Applicant: EWHA UNIVERSITY-INDUSTRY COLLABORATION FOUNDATION
    Inventors: Juyoung Yoon, Guo Zhiqian
  • Publication number: 20140323322
    Abstract: A chemical sensor comprising: a hydrogel layer, comprising one or more molecular recognition agents and a 2DPC self-assembling array; and a mirror layer. A method for analyzing a sample or bodily fluid, comprising: obtaining a sample or bodily fluid; placing an amount of the sample or bodily fluid onto a chemical sensor, comprising: a hydrogel layer, comprising a molecular recognition agent and a 2DPC self-assembling array; a tethering hydrogel layer; a mirror layer; and a membrane filter layer, allowing the bodily fluid to interact with the hydrogel layer; and allowing ambient or artificial light to pass through the hydrogel layer onto the mirror layer and observing a change in diffraction versus a control.
    Type: Application
    Filed: October 4, 2012
    Publication date: October 30, 2014
    Inventor: Sanford A. Asher