Including Titration Or Ph Determination Patents (Class 436/163)
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Patent number: 8859288Abstract: Methods to produce pH-sensitive microparticles that have an active agent dispersed in a polymer matrix have certain advantages over microcapsules with an active agent encapsulated in an interior compartment/core inside of a polymer wall. The current invention relates to pH-sensitive microparticles that have a corrosion-detecting or corrosion-inhibiting active agent or active agents dispersed within a polymer matrix of the microparticles. The pH-sensitive microparticles can be used in various coating compositions on metal objects for corrosion detecting and/or inhibiting.Type: GrantFiled: July 5, 2012Date of Patent: October 14, 2014Assignee: The United States of America as Represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Wenyan Li, Jerry W. Buhrow, Scott T. Jolley, Luz M. Calle
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Publication number: 20140302615Abstract: Provided is a cathode active material containing a Ni-based lithium mixed transition metal oxide. More specifically, the cathode active material comprises the lithium mixed transition metal oxide having a composition represented by Formula I of LixMyO2 wherein M, x and y are as defined in the specification, which is prepared by a solid-state reaction of Li2CO3 with a mixed transition metal precursor under an oxygen-deficient atmosphere, and has a Li2CO3 content of less than 0.07% by weight of the cathode active material as determined by pH titration. The cathode active material in accordance with the present invention and substantially free of water-soluble bases such as lithium carbonates and lithium sulfates and therefore has excellent high-temperature and storage stabilities and a stable crystal structure.Type: ApplicationFiled: June 18, 2014Publication date: October 9, 2014Applicant: LG Chem, Ltd.Inventors: Hong-Kyu Park, Sun sik Shin, Sin young Park, Ho suk Shin, Jens M. Paulsen
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Patent number: 8852882Abstract: A FRET donor-acceptor pair for use as a biosensor, comprising at least two fluorescence proteins, wherein at least one fluorescence protein is stable with respect to a parameter to be detected by the biosensor and at least one fluorescence protein is unstable with respect to the parameter to be detected by the biosensor.Type: GrantFiled: August 16, 2011Date of Patent: October 7, 2014Assignee: Evocatal GmbHInventors: Karl Erich Jaeger, Thomas Drepper, Stephan Endres, Janko Potzkei, Achim Heck, Franco Circolone
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Publication number: 20140287517Abstract: This invention relates to methods and means for performing pool and other water and liquid testing. Some embodiments of the methods and means of the invention also incorporate additional functionality including, but not limited to communication, sensing, display and data processing elements. Various embodiments of the methods and means of the invention may be performed by and/or implemented in hardware, in software, by one or more entities, and/or by some combination of hardware, software and/or one or more entities.Type: ApplicationFiled: March 14, 2014Publication date: September 25, 2014Inventor: Alfred M. Haas
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Publication number: 20140273265Abstract: A microfluidic cartridge for assaying an analyte comprises one or more test channels, each having a lumen; one or more reference solution channels in fluid communication with the test channels; one or more sample channels in fluid communication with the test channels; one or more sensors at least partially exposed in the lumen of the test channels; and a processor coupled to the one or more sensors for measuring properties of the analyte to determine at least one of an identity, concentration, dose, and dosage of the analyte.Type: ApplicationFiled: March 13, 2014Publication date: September 18, 2014Inventors: Joseph FEINGOLD, Hector Luis Penagos-Vargas
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Publication number: 20140256055Abstract: A method for detecting hydrocarbons is described. The method includes performing a remote sensing survey of a survey location to identify a target location. Then, an underwater vehicle (UV) is deployed into a body of water and directed to the target location. The UV collects measurement data within the body of water at the target location, which is then analyzed to determine whether hydrocarbons are present at the target location.Type: ApplicationFiled: November 9, 2012Publication date: September 11, 2014Inventors: Robert J. Pottorf, Leonard J. Srnka, William Bond, Sebastien L. Dreyfus, Michael Lawson, William P. Meurer, Daniel P. Cherney, Steven R. May, William G. Powell, Christoper J. Vandewater, Mehmet D. Ertas, Sumathy Raman, Aaron B. Regberg, A. Lucie N'Guessan, Amelia C. Robinson, Kurt W. Rudolph
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Patent number: 8828728Abstract: An aquatic environment monitoring system and method that includes correction for adverse conditions in the monitoring system involving the development of confidence levels for certain conditions in the monitoring system using stored information related to the aquatic environment and/or the monitoring system. Corrections to adverse conditions may be made by the environment monitoring system automatically by the monitoring system and manually via communications to a user of the system.Type: GrantFiled: December 13, 2012Date of Patent: September 9, 2014Assignee: Step Ahead Innovations, Inc.Inventor: James E. Clark
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Publication number: 20140248646Abstract: A fluorophore and methods of detecting cations and hydrophobic environments using the fluorophore are disclosed. The fluorophore includes an imidazo[1,5-a]pyridinium ion core and has the formula where R1, R2, R3 and X? are as defined in the specification, and n is an integer from 1 to 4.Type: ApplicationFiled: March 4, 2013Publication date: September 4, 2014Applicant: Indiana University Research and Technology CorporationInventor: Indiana University Research and Technology Corporation
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Publication number: 20140220699Abstract: A pH-buffer measurement system that has at least one source for modifying the pH of a fluid entering the system, the source selected from an acid source and a base source. The acid source adds an acid equivalent to provide an acid reacted fluid and the base source adds a base equivalent to provide a base reacted fluid. The source is in fluid communication with a flow path and a component for determining a fluid characteristic of the acid reacted fluid or the base reacted fluid. The fluid characteristic that is measured is any one of a gas phase pressure, an electrical conductivity, or thermal conductivity.Type: ApplicationFiled: March 15, 2013Publication date: August 7, 2014Applicant: MEDTRONIC, INC.Inventors: Bryant J. Pudil, Thomas E. Meyer, David B. Lura, Martin T. Gerber
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Patent number: 8785207Abstract: The present invention relates generally a method and apparatus for measuring multiple parameters in-situ in a sample collected from an environmental system via a single device. In one embodiment, the method includes collecting the sample from said environmental system via the single device, measuring a first parameter of the sample in-situ via the single device, adding a reagent tot the sample within the single device to create a reagent infused sample and measuring a second parameter of the sample in-situ via the single device using the reagent infused sample.Type: GrantFiled: September 11, 2009Date of Patent: July 22, 2014Assignee: SRI InternationalInventors: Ryan J. Bell, R. Timothy Short, Strawn K. Toler, Robert H. Byrne
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Publication number: 20140199775Abstract: A subsea monitoring device comprises a metal part (12) disposed in a polymeric sheath (11,14), and means (10) for providing a sensible indication of pH at an interface between the part and the sheath. The part may be the metal shell of a connector. When a cable (13) extends from the connector, adjacent the connector the cable would be covered by the polymeric sheath. The said means (10) may comprise a chemical indicator and the sheath is preferably sufficiently translucent to allow visual observation of the indicator. The chemical indicator may comprise phenolphthalein.Type: ApplicationFiled: May 14, 2013Publication date: July 17, 2014Applicant: AKER SUBSEA LIMITEDInventor: Philip Michael Bagley
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Publication number: 20140186962Abstract: The present invention relates to an optical H+-sensor, comprising an H+-indicator material, wherein the H+-indicator material is present between a support material and a H+-permeable layered structure, the layered structure comprising an H+-permeable hydrophilic layer and an H+-permeable cation exchange layer. Further, the invention relates to a method for determining the H+-concentration, e.g. expressed as pH, in a product or sample thereof, the method comprising contacting the product or sample with an optical H+-sensor according to the invention, measuring an optical property of the indicator material, and determining the H+-concentration of the product or sample based on said optical property.Type: ApplicationFiled: March 28, 2012Publication date: July 3, 2014Applicant: Nederlandse Organisatie voor toegepast- natuurwetenschappelijk onderzoek TNOInventors: Jacobus Johannes Frederik van Veen, Cornelis Gerardus Josephus Koopal
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Patent number: 8753896Abstract: A method of monitoring a surfactant in a microelectronic process is disclosed. Specifically, the monitoring of a surfactant occurs by studying the fluorescence or electromagnetic emission of a sample collected from a microelectronic process.Type: GrantFiled: April 5, 2007Date of Patent: June 17, 2014Assignee: Nalco CompanyInventors: Brian V. Jenkins, John E. Hoots, Amy M. Tseng
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Patent number: 8753586Abstract: An apparatus for chemical separations includes a microfluidic substrate having an outlet aperture for outputting an eluent of a sample, a spray unit having an inlet to receive the eluent and an outlet to emit a spray of the eluent, and a force-applying unit. The spray unit has a deformable portion defining the inlet and having an elastic modulus that is lower than an elastic modulus of the microfluidic substrate. The force-applying unit, such as a spring, is disposed to urge the deformable portion in contact with the substrate to form a substantially fluid-tight seal.Type: GrantFiled: March 5, 2010Date of Patent: June 17, 2014Assignee: Waters Technologies CorporationInventors: David P. Prentice, Russell L. Keene, Stanilaw Koziol, Joseph D. Michienzi, Paul E. Linderson
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Publication number: 20140154815Abstract: A method of changing the fluorescent properties of a complex, the method comprising: providing a first complex comprising a multidentate ligand that is coordinated to a lanthanide ion, wherein the lanthanide is selected from europium and terbium and the multidentate ligand has at least one optionally substituted phthalimide group coordinated to the lanthanide ion, contacting the complex with an aqueous liquid medium under appropriate conditions, such that at least one phthalimide group is hydrolysed to a phthalamate group, to form a second complex. Complexes and compounds are also disclosed.Type: ApplicationFiled: April 13, 2012Publication date: June 5, 2014Applicant: LONDON METROPOLITAN UNIVERSITYInventors: Sim-Wan Annie Bligh, Nicholas Paul Chatterton, Nicholas James Wardle, Jason Lee Sarris, Gaoyun Chen
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Publication number: 20140147923Abstract: Methods and systems for testing fluid samples include a diffused air flotation (DAF) system and a jar. The jar includes a diffuser for injecting the diffused air into the jar and a tap for drawing a fluid out of the jar.Type: ApplicationFiled: November 19, 2013Publication date: May 29, 2014Applicant: BAKER HUGHES INCORPORATEDInventors: Stephen J. Wiacek, Bingbing Guo
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Patent number: 8728758Abstract: A method of measuring a metabolic activity (MA) of a cell is provided. The method comprising independently measuring in an extracellular environment of the cell, time-dependent acidification profiles due to secretion of: (i) non-volatile soluble metabolic products; (ii) non-volatile soluble metabolic products and volatile soluble metabolic products; and (iii) volatile soluble metabolic products; wherein at least one of the time dependent acidification profiles is indicative of the metabolic activity of the cell. Also provided are clinical methods which make use of the assay.Type: GrantFiled: April 4, 2012Date of Patent: May 20, 2014Assignee: Ramot at Tel-Aviv University Ltd.Inventors: Reuven Tirosh, Fernando Patolsky, Hagit Peretz-Soroka
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Patent number: 8709815Abstract: Methods and devices are disclosed providing techniques for measuring the amount of biodiesel in a fuel sample. The methods may be used in the field without the use of laboratory equipment. The biodiesel in the sample is converted to the corresponding free acid which can be isolated and quantified to provide information regarding the amount of biodiesel in the original sample.Type: GrantFiled: October 31, 2012Date of Patent: April 29, 2014Assignee: Dexsil CorporationInventors: Theodore B. Lynn, Lawrence M. Sacramone
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Publication number: 20140106464Abstract: Method for analyzing the alkalinity conditions in aqueous liquids, comprising: sampling a known amount of the aqueous liquid and placing it in a container of known volume, measuring pH in the sampled liquid and pressure in the container, adding a known amount of CO2 to the sampled liquid, and measuring pH in the sampled liquid and the pressure in the container, and finally calculating the total alkalinity based on the values from the performed measurements. An apparatus for conducting the method is also described as well as a method for controlling chemistry of a glycol containing liquid in a system for recovery of glycol.Type: ApplicationFiled: May 11, 2012Publication date: April 17, 2014Inventors: Arne Dugstad, Marion Seiersten
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Publication number: 20140080222Abstract: The present invention relates to a new type of fluorescent with the following formula (I), its preparation process, and also an optical pH sensor which comprises this fluorescent dye immobilized on an analyte-permeable carrier.Type: ApplicationFiled: March 28, 2012Publication date: March 20, 2014Applicant: SARTORIUS STEDIM BIOTECH GMBHInventors: Daniel Riechers, Eberhard Wuenn
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Publication number: 20140080172Abstract: Disclosed are systems and methods for monitoring chemical reaction processes in or near real-time. One method may include containing a fluid within a flow path, the fluid having a chemical reaction occurring therein, optically interacting at least one integrated computational element with the fluid, thereby generating optically interacted light, and producing an output signal based on the optically interacted light that corresponds to a characteristic of the chemical reaction.Type: ApplicationFiled: September 14, 2012Publication date: March 20, 2014Applicant: Halliburton Energy Services, Inc.Inventors: Ola Tunheim, Robert P. Freese, Alexis Wachtel, II, James R. MacLennan
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Publication number: 20140065719Abstract: A detection method for a substance and a system thereof are provided. The detection method for a substance contained in a sample includes providing a reagent in reaction with the substance to form a chelate; and pressurizing the substance to accumulate the chelate.Type: ApplicationFiled: September 4, 2012Publication date: March 6, 2014Applicant: Taiwan Semiconductor Manufacturing Company, Ltd.Inventors: Chi-Wen Kuo, Yu-Kun Hung, Tzu-Sou Chuang
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Patent number: 8663563Abstract: A reflective diffractometric hydrogel sensor includes an upper layer, including a microfluidic chamber formed from a substantially transparent material and configured to contain a solution, a reflective diffraction grating positioned within the microfluidic chamber, the diffraction grating including a plurality of hydrogel strips configured to change in dimension in response to a stimulus, each hydrogel strip having a top surface coated with a reflective material and a bottom surface in contact with the upper layer substrate, and a reflective surface below the reflective diffraction grating wherein when a coherent light is incident upon and reflected from the upper layer at an angle substantially normal to the upper layer an interference diffraction pattern results, including a first diffraction mode, a light intensity of which indicates the relative distance between the top surfaces of the plurality of hydrogel strips and the reflective surface.Type: GrantFiled: December 5, 2011Date of Patent: March 4, 2014Assignees: Purdue Research Foundation, Board of Regents, The University of Texas SystemInventors: Cagri Savran, Chun-Li Chang, Zhenwen Ding, Babak Ziaie, Andrew Ellington, Venkata Naga Lakshmi Rekha Patchigolla
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Publication number: 20140051177Abstract: The fiber optic probe (7) comprises: a first optical fiber (9) to convey an electromagnetic radiation towards a measuring area at an exit end of said first optical fiber (9); a second optical fiber (11) to collect an electromagnetic radiation from said measuring area, the second optical fiber comprising an entrance end arranged in the measuring area and adjacent to the exit end of the first optical fiber. The exit end of the first optical fiber and the entrance end of the second optical fiber (11) are treated so that at least part of the electromagnetic radiation conveyed along the first optical fiber exits laterally from the first optical fiber and enters laterally in the second optical fiber. Moreover, in the measuring area an indicating material (15) is arranged, indicating a parameter to be measured with the probe.Type: ApplicationFiled: November 30, 2011Publication date: February 20, 2014Inventors: Francesco Baldini, Cosimo Trono
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Patent number: 8642350Abstract: A sensor material of the type comprising a long-decay photoluminescent, protonable dye embedded in a suitable polymeric matrix, is used for generating a specific optical response to two different analytes present in a sample, thus allowing selective determination of the two analytes in the sample. Also described is a method for the simultaneous sensing of a first and second analyte in a sample. The method comprises the steps of irradiating a sensor material of the type comprising a long-decay photoluminescent protonable dye embedded in a suitable polymeric matrix with light of one or two wavelengths, determining photoluminescence intensity and lifetime signals originating from the sensor, and correlating the photoluminescence intensity signal with a concentration of the first analyte and the photoluminescence lifetime signal(s) with the concentration of the second analyte.Type: GrantFiled: March 29, 2011Date of Patent: February 4, 2014Assignee: University College Cork, National University of Ireland, CorkInventor: Dmitri Papkovsky
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Publication number: 20140030812Abstract: Devices and methods for measuring the acidity of airborne matter are provided. A filter can be impregnated with an indicator dye which changes color in response to changes in acidity. After the sample passes through the filter, the filter can be analyzed using UV-visible spectrometry.Type: ApplicationFiled: September 10, 2013Publication date: January 30, 2014Applicant: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC.Inventor: MYOSEON JANG
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Publication number: 20140030815Abstract: Disclosed is a pinhole inspection apparatus, system and method for a membrane electrode assembly of a fuel cell, which can easily detect the position of a pinhole using water and a pH test paper from discoloration caused when the water is in contact with the pH test paper through the pinhole, thus solving the existing problems and allowing the membrane electrode assembly to be reused after the inspection. In particular, a lower fixture is configured to support the membrane electrode assembly and water is uniformly distributed on an upper surface of the membrane electrode assembly. A pH test paper is inserted between the membrane electrode assembly and the lower fixture and discolored upon coming in contact with water that passes through a pinhole in the membrane electrode assembly, thus detecting the presence and position of the pinhole.Type: ApplicationFiled: November 27, 2012Publication date: January 30, 2014Applicant: HYUNDAI MOTOR COMPANYInventors: Ji Yeon Park, Bo Ki Hong, Sang Yeoul Ahn
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Publication number: 20140004619Abstract: An apparatus and method to measure water content and water pH of multiphase fluid mixtures of water and oil. The apparatus employs a water content sensor containing an infrared light source and a photodetector. The pH sensor includes a pH indicator that exhibits a color change in an oleophobic coating including an image recording device. The apparatus and method may be applied to measure water fraction and pH within oil/water pipelines.Type: ApplicationFiled: June 29, 2012Publication date: January 2, 2014Applicant: SOUTHWEST RESEARCH INSTITUTEInventors: Leonardo J. CASERES, James F. DANTE
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Patent number: 8609355Abstract: Methods, devices, and kits are provided herein for the accurate and rapid detection of disease causing microbes in a sample by the detection of microbial components of which correlate to the presence of the microbe. Kits include a first binding agent operatively coupled to an immobilized support; and a second binding agent operatively coupled to one or more pH indicating moieties wherein the first and second binding agents bind with sufficient specificity to the microbial component to permit detection of that component which correlates to the presence of the microbe in the sample.Type: GrantFiled: July 25, 2012Date of Patent: December 17, 2013Assignee: Indicator Systems International, Inc.Inventors: Gerald F. Swiss, Laurie B. F. Stellman
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Patent number: 8585983Abstract: The disclosed invention is a composition for a humidity indicating device comprising (a) an organic pH indicator dye compound, (b) a Bronsted acid or base, and (c) a polyol having the general formula HOCH2—(CHOH)n—CH2OH, wherein n can be 0, 1, 2, 3 or 4, wherein said components (a), (b), and (c) do not contain halogen and/or heavy metals. Furthermore, the invention relates to a humidity indicator device comprising a sheet substrate and the composition for a humidity indicating device containing no heavy metals or halogen compounds, and to a process for preparing said humidity indicator device.Type: GrantFiled: June 22, 2011Date of Patent: November 19, 2013Assignee: Sud-Chemie IP GmbH & Co. KGInventors: Johanna Knyrim, Stefan Dick
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Patent number: 8580515Abstract: A method for surface modification of single walled carbon nanotubes is described. In one embodiment, the method includes the steps of providing a detergent solution, adding a plurality of single walled carbon nanotubes into the detergent solution, performing a first sonication to disperse the single walled carbon nanotubes in the detergent solution, and performing a second sonication after the first sonication to make detergent encased single walled carbon nanotubes. At least one of the plurality of single walled carbon nanotubes is at least partially wrapped by one or more detergent molecules to make it a detergent encased single walled carbon nanotube. In one embodiment, the detergent comprises SDS, PSS or a combination of them. The surface modified carbon nanotubes can be used to detect a chemical compound by associating a solution of the surface modified nanotubes with the chemical compound and optically detecting a chemical property change of the solution.Type: GrantFiled: November 17, 2006Date of Patent: November 12, 2013Assignee: Board of Trustees of the University of ArkansasInventors: Wei Zhao, Chulho Song
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Publication number: 20130295681Abstract: The present invention relates to a device, system and a method for evaluating, measuring and assessing vitality, energy and stress levels in an individual and/or substance, and in particular, to such a device, system and method in which personal assessment and decision support is provided based on the measured levels of vitality, energy and stress.Type: ApplicationFiled: December 15, 2011Publication date: November 7, 2013Inventor: Nader Butto
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Patent number: 8574921Abstract: Provided is an optical sensing membrane, including a mixture of two or more fluorescent dyes for detection of dissolved oxygen concentration, pH and temperature, immobilized on a support, a detection device including the optical sensing membrane and a detection method using the detection device.Type: GrantFiled: April 29, 2009Date of Patent: November 5, 2013Assignee: Industry Foundation of Chonnam National UniversityInventors: Jong Il Rhee, Chun-Kwang Kim, Ok-Jae Sohn
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Publication number: 20130280749Abstract: A FRET donor-acceptor pair for use as a biosensor, comprising at least two fluorescence proteins, wherein at least one fluorescence protein is stable with respect to a parameter to be detected by the biosensor and at least one fluorescence protein is unstable with respect to the parameter to be detected by the biosensor.Type: ApplicationFiled: August 16, 2011Publication date: October 24, 2013Applicant: EVOCATAL GMBHInventors: Karl Erich Jaeger, Thomas Drepper, Stephan Endres, Janko Potzkei, Achim Heck, Franco Circolone
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Publication number: 20130256239Abstract: A coordinated system for the treatment of water includes (a) a test kit including an indicator having a changeable color which is adapted to a predetermined aqueous environmental condition and an associated chart including colors associated with a range of environmental conditions; and at least one chemical agent having a color which corresponds to a color of the indicator associated with an environmental condition outside of a desired range.Type: ApplicationFiled: March 27, 2012Publication date: October 3, 2013Applicant: Asia Connection LLC.Inventors: Mitch Saccoccio, Jonathan Bonelli
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Publication number: 20130248758Abstract: Provided is a cathode active material containing a Ni-based lithium mixed transition metal oxide. More specifically, the cathode active material comprises the lithium mixed transition metal oxide having a composition represented by Formula I of LixMyO2 wherein M, x and y are as defined in the specification, which is prepared by a solid-state reaction of Li2CO3 with a mixed transition metal precursor under an oxygen-deficient atmosphere, and has a Li2CO3 content of less than 0.07% by weight of the cathode active material as determined by pH titration. The cathode active material in accordance with the present invention and substantially free of water-soluble bases such as lithium carbonates and lithium sulfates and therefore has excellent high-temperature and storage stabilities and a stable crystal structure.Type: ApplicationFiled: April 25, 2013Publication date: September 26, 2013Applicant: LG CHEM, LTD.Inventors: Hong Kyu Park, Sun Sik Shin, Sin Young Park, Ho Suk Shin, Jens M. Paulsen
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Patent number: 8518344Abstract: The disclosed invention is a humidity indicating composition comprising (a) an organic pH indicator dye compound, (b) a Bronsted acid or base, (c) a polyol having the general formula HOCH2—(CHOH)n—CH2OH, wherein n can be 0, 1, 2, 3 or 4, and (d) a solvent; wherein said components (a), (b), (c) and (d) do not contain halogen and/or heavy metals. Furthermore, the invention relates to a humidity indicator card comprising a sheet substrate and the humidity indicating composition from which the solvent has been allowed to evaporate, and to a process for preparing said humidity indicator card.Type: GrantFiled: December 23, 2010Date of Patent: August 27, 2013Assignee: Sud-Chemie IP GmbH & Co., KGInventors: Johanna Knyrim, Stefan Dick
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Publication number: 20130210156Abstract: Described herein are optical agents, including compositions, preparations and formulations, for monitoring the pH of a fluid. Optical agents described herein include photonic nanostructures and nanoassemblies including supramolecular structures, such as shell cross-linked micelles, that incorporate at least one linking group comprising one or more photoactive moieties that provide functionality as exogenous agents for a range of pH monitoring applications. Optical agents described herein comprise supramolecular structures having linking groups imparting useful optical and structural functionality. In an embodiment, for example, the presence of linking groups function to covalently cross link polymer components to provide a cross-linked shell stabilized supramolecular structure, and also impart useful optical functionality, for example by functioning as a fluorophore.Type: ApplicationFiled: May 13, 2011Publication date: August 15, 2013Inventors: Karen L. Wooley, Richard B. Dorshow, John N. Freskos, William L. Neumann, Jeng J. Shieh, Nam S. Lee, Yun Lin, Guorong Sun
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Patent number: 8497134Abstract: System and method for detecting and measuring chemical perturbations in a sample. The system and method are useful for non-invasive pH monitoring of blood or blood products sealed in storage bags.Type: GrantFiled: April 23, 2007Date of Patent: July 30, 2013Assignee: Blood Cell Storage, Inc.Inventors: Michael W. Reed, Steven J. Geelhood, Paul C. Harris, Lynn M. Barker, Perry Hargrave, Oliver Nanassy
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Patent number: 8492160Abstract: The invention is a device including array of aciive regions for use in reacting one or more species in at least two of the active regions in a sequential process, e.g., sequential reactions. The device has a transparent substrate member, which has a surface region and a silane material overlying the surface region. A first active region overlies a first portion of the silane material. The first region has a first dimension of less than 1 micron in size and has first molecules capable of binding to the first portion of the silane material. A second active region overlies a second portion of the silane material. The second region has a second dimension of less than 1 micron in size, second molecules capable of binding to the second portion of the active region, and a spatial distance separates the first active region and the second active region.Type: GrantFiled: March 9, 2010Date of Patent: July 23, 2013Assignee: The United States of America as Represented by the Administrator of the National Aeronautics and Space AdministrationInventors: Lawrence A. Wade, Charles Patrick Collier
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Patent number: 8492161Abstract: Disclosed is a method for quantitatively analyzing a functional group on the surface of a solid material. The functional group is carboxylic group while the solid material is carbon nano-tubes. The carboxylic group reacts with sodium hydrogen carbonate, thus turning the carboxylic groups into sodium carboxylate while consuming the sodium ions in the solution. The carbon nano-tubes are separated from the sodium hydrogen carbonate solution. The number of the sodium ions before and after the reaction is analyzed. Moreover, the sodium carboxylate carried on the reacted carbon nano-tubes with reacts with hydrochloric acid solution, thus dissolving the sodium ions in the hydrochloric acid solution. The carbon nanotubes are separated from from the hydrochloric acid solution. The amount of the sodium ions is analyzed before and after the reaction in the hydrochloric acid solution.Type: GrantFiled: August 25, 2011Date of Patent: July 23, 2013Assignee: Atomic Energy Council—Institute of Nuclear Energy ResearchInventors: Meng-Jun Fu, Kuan-Yin Chen, Chia-Chieh Chen
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Publication number: 20130122597Abstract: A multi-purpose reagent composition is used for simultaneously determining concentrations of at least two analytes in a water sample. The two analytes are selected from the group consisting of free chlorine, pH, anionic polymer, and phosphates. In one embodiment, the multi-purpose reagent composition is for simultaneously determining the concentration of free chlorine and pH and comprises a free chlorine sensitive dye and pH indicator. In another embodiment, the reagent composition is for simultaneously determining of free chlorine and anionic polymer and includes a free chlorine sensitive dye, a pH buffer, cationic dye, and organic co-solvent. Thus, the pairs of free chlorine and pH or free chlorine and anionic polymer are determined using a single reagent composition. The reagent composition can also be the main reagent for one analyte analysis when it is used alone and also function as an ancillary reagent when it is combined with a second reagent composition for the determination of another analyte.Type: ApplicationFiled: August 3, 2010Publication date: May 16, 2013Inventors: Caibin Xiao, Bingzhi Chen, Chunbo Yu, Hong Xu
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Patent number: 8432171Abstract: An analyte concentration, in a sample fluid, is determined by differential measurement. Two or more capacitive field effect sensors have an identical basic structure and are arranged in a shared measuring cell. One of the sensors forms a measuring sensor with an active transductor layer. Another sensor forms a reference sensor without an active transductor layer. The sensors are contacted with the sample fluid and the sensors, have an associated reference electrode, or have a shared reference electrode. A bias voltage composed of an electric DC voltage and a superimposed AC voltage is applied between each sensor and associated reference electrode(s) Capacitance changes due to the analyte are eliminated by controlling the bias voltage applied to the measuring sensor in a closed control loop. A measuring signal is obtained by calculating a difference between voltage values representative of DC voltage potentials applied to the measuring sensor and reference sensor, respectively.Type: GrantFiled: April 28, 2010Date of Patent: April 30, 2013Assignee: Buerkert Werke GmbHInventors: Thomas Coppe, Jean-Luc Henry, Michael Schoening
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Publication number: 20130102021Abstract: A new class of pH sensitive fluorescent dyes and assays relating thereto are described. The dyes and assays are particularly suited for biological applications including phagocytosis and monitoring intracellular processes. The pH sensitive fluorescent dyes of the present invention include compounds of Formula I: wherein the variables are described throughout the application.Type: ApplicationFiled: September 13, 2012Publication date: April 25, 2013Applicant: LIFE TECHNOLOGIES CORPORATIONInventors: Daniel BEACHAM, Jeffrey Dzubay, Kyle Gee, Vladimir Martin, Aleksey Rukavishnikov
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Patent number: 8415168Abstract: An apparatus for capillary ion chromatography comprising a suppressor comprising flow-through ion exchange packing in a housing and capillary tubing formed of a permselective ion exchange membrane, and at least partially disposed in said ion exchange packing. Also, a recycle conduit for aqueous liquid from the detector to the packing. Further, the capillary tubing may have weakly acidic or weakly basic functional groups. Also, a method for using the apparatus.Type: GrantFiled: May 23, 2012Date of Patent: April 9, 2013Assignee: Dionex CorporationInventors: Yan Liu, Victor Manuel Berber Barreto, Christopher A. Pohl, Nebojsa Avdalovic
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Publication number: 20130059069Abstract: There is provided a method for testing a glass material and a method for evaluating a glass material capable of preventing a generation of a gap between an evaluation result and an actual degradation state of the surface of a lens, and also to provide a method for producing an optical element capable of sufficiently exhibiting chemical durability possessed by the optical element, which is the method for testing a glass material, to perform a test regarding a chemical durability of a glass material, comprising examining a correlation between a variation of hydrogen ion concentration indexes of a process liquid in which the glass material is immersed, and a variation of chemical durability index values of a prescribed type of the glass material.Type: ApplicationFiled: September 6, 2012Publication date: March 7, 2013Applicant: HOYA CORPORATIONInventors: Shigeru Aoyagi, Jun Nakamura, Kazuo Tachiwana, Junko Akojima
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Patent number: 8377700Abstract: Systems and methods related to compositions including hydrogels and photoluminescent nanostructures are described. The compositions can undergo a change in a physical, chemical, dielectric, or other property upon exposure to an altering stimulus. Changes in one or more properties of the hydrogel may impart a change in the photoluminescence of the nanostructures embedded in the hydrogel.Type: GrantFiled: February 26, 2010Date of Patent: February 19, 2013Assignee: Massachusetts Institute of TechnologyInventors: Michael S. Strano, Paul W. Barone, Jin-Ho Ahn, Ardemis Anoush Boghossian, Rene Ortiz-Garcia, Hyeonseok Yoon, Jingqing Zhang
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Patent number: 8372789Abstract: Methods that comprise selecting proppant for use in a fracturing fluid based on one or more factors, wherein the one or more factors comprise an interaction between the proppant and the fracturing fluid. Methods that comprise designing a treatment fluid that comprises a gelled base fluid and a particulate based on one or more factors, wherein the one or more factors comprise an interaction between the particulate and the gelled base fluid.Type: GrantFiled: January 16, 2009Date of Patent: February 12, 2013Assignee: Halliburton Energy Services, Inc.Inventors: Phillip C. Harris, Stanley J. Heath, Harold G. Walters
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Patent number: 8372651Abstract: A method of monitoring a surfactant in a microelectronic process is disclosed. Specifically, the monitoring of a surfactant occurs by studying the absorbance of a sample collected from a microelectronic process.Type: GrantFiled: April 5, 2007Date of Patent: February 12, 2013Assignee: Nalco CompanyInventors: Amy M. Tseng, John E. Hoots, Brian V. Jenkins
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Publication number: 20130029374Abstract: A method, and a measuring point for performing the method, for measuring at least one physical and/or chemical, process variable of a medium contained in a single use container. A single use sensor is connected with the single use container. The single use sensor with the single use container is sterilized by radiation, especially beta or gamma radiation. An electronics unit is connected with the single use sensor, and the electronics unit is connected with at least one superordinated system via at least one interface. The electronics unit and/or the single use sensor are/is supplied with energy, and measurement data of the single use sensor are registered. The measurement data are processed by the electronics unit and/or the superordinated system, data, including measurement data, are transmitted to the superordinated system and/or received from the superordinated system, and, after termination of one or more measuring cycles, the electronics unit is released from the single use sensor.Type: ApplicationFiled: July 24, 2012Publication date: January 31, 2013Applicant: Endress + Hauser Conducta Gesellschaft für Mess- und Regeltechnik mbH + Co. KGInventors: Andreas Eberheim, Christian Fanselow