With Step Of Insertion Or Removal From Test Line Patents (Class 436/48)
  • Patent number: 11383396
    Abstract: An interactive laboratory robotic system is described that includes devices for use in a laboratory including a robotic assistant that can perform tasks and that can be controlled and configured by humans. The robot may assist personnel in performing repetitive tasks within a laboratory, and capture and store transactional and analytical data, such as during a DNA sequencing process. The robot may include sensors and/or cameras to detect, recognize, and track objects in an environment, and a manipulable arm having a hand for grasping objects. Other components of the system may include a sample tray graspable by the robot; a tray carriage for holding sample trays within equipment; an interactive shelf for holding sample trays; a mobile cart for mating with and charging the robot; and an accessory unit to enable the robot to open doors of equipment. The system may help to reduce or eliminate mistakes by personnel.
    Type: Grant
    Filed: April 14, 2017
    Date of Patent: July 12, 2022
    Assignee: Tesseract Ventures, LLC
    Inventor: John Boucard
  • Patent number: 11175301
    Abstract: An automatic analyzer includes: a reagent mounting unit 103 in which a plurality of reagent bottles 10 are installed when a reagent bottle 10 is loaded into the automatic analyzer; a reagent conveying mechanism 101 including a gripper mechanism 106; and a reagent mounting mechanism 102 for moving the reagent mounting unit 103 between an installation position at which an operator installs the reagent bottle 10 in the reagent mounting unit 103 and a position at which the gripper mechanism 106 grips the reagent bottle 10. It is thereby possible to achieve saving of a mechanism installation space and reduction of the number of constituent components, automatically carry out an operation from opening of the reagent bottle to loading of the reagent bottle into the reagent disk, and alleviate an operator's burden.
    Type: Grant
    Filed: August 23, 2016
    Date of Patent: November 16, 2021
    Assignees: HITACHI HIGH-TECH CORPORATION, ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Takamichi Mori, Kouhei Nonaka, Masaki Hara, Masato Ishizawa, Hitoshi Tokieda, Stephan Sattler
  • Patent number: 11042605
    Abstract: Discussed herein are systems, methods, and apparatuses for quality control monitoring of laboratory analyzers. A method can include receiving test results from laboratory analyzers, the test results corresponding to a same analyte, determining a standard deviation of differences (SDD) among pairs of the multiple test results, calibrating the laboratory analyzer based on the determined SDD.
    Type: Grant
    Filed: June 24, 2019
    Date of Patent: June 22, 2021
    Assignee: CCQCC Corp.
    Inventor: George S. Cembrowski
  • Patent number: 11009517
    Abstract: Some embodiments of the disclosure provide a sample rack scheduling control method. The method includes the following steps: respectively obtaining a state of each position node on each preset delivery path, wherein the state of each position node includes an available state and an occupancy state; and for each of the delivery paths, if a target position node on the delivery path and position nodes between the target position node and a start position node all are in the available state, marking the target position node on the delivery path and the position nodes between the start position node and the target position node all as the occupancy state, and controlling a current sample rack at the start position node to move to the target position node. The present disclosure further provides a sample rack scheduling control system and a medical detection device.
    Type: Grant
    Filed: November 29, 2018
    Date of Patent: May 18, 2021
    Assignee: Shenzhen New Industries Biomedical Engineering Co, Ltd
    Inventors: Junhui Tang, Caiqing Zhong, Xiaotao Chen, Jiang Li, Shujuan Chen, Ying Hu
  • Patent number: 10739321
    Abstract: A method of multiplexing the operation of a sample preparation and analysis system is disclosed. The system includes a sample preparation system capable of preparing a first sample in accordance with a first assay that is selected from a database containing a plurality of unique assays and preparing a second sample in accordance with a second, different assay. The method includes separately transporting the first and second prepared samples to an analysis station having first and second separation channels and an analyzer comprising a mass spectrometer. The method further includes simultaneously analyzing the first prepared sample with the analyzer in accordance with the first selected assay and separating the second prepared sample with the second separation channel in accordance with the second selected assay.
    Type: Grant
    Filed: August 30, 2018
    Date of Patent: August 11, 2020
    Assignee: THERMO FISHER SCIENTIFIC OY
    Inventors: Robert DeWitte, Juhani Siidorov, Vesa Nuotio, Raimo Salminen, Jarmo Vehkomaki, Jukka Saukkonen, Bill Ostman, Joseph M. Senteno, John Edward Brann, III, Joseph L. Herman, Jeffrey A. Zonderman, Terry N. Olney
  • Patent number: 10607724
    Abstract: To facilitate management of the entirety of one or a plurality of clinical laboratories. This information processing apparatus is used in management of a clinical laboratory in which an analyzer configured to analyze specimens is installed. The information processing apparatus includes: a communication section configured to communicate with a terminal operable by a user; and a controller configured to control display of the terminal via the communication section. On the basis of information collected from a plurality of analyzers installed in one or a plurality of clinical laboratories and from apparatuses relevant to the analyzers, the controller causes the terminal to display a screen including an index that indicates a status of the entirety of the one or the plurality of clinical laboratories. In response to the user selecting the index displayed in the screen, the controller causes the terminal to display the selected index so as to be divided in a plurality of categories.
    Type: Grant
    Filed: August 10, 2016
    Date of Patent: March 31, 2020
    Assignee: SYSMEX CORPORATION
    Inventors: Akio Miyauchi, Naoki Tsuro, Norio Kowata, Naoki Kai, Shirou Kuwaoka, Yukihisa Minematsu, Mark Dahlberg, Steve Postma, Chris Carrier, Jackie Guenther, Anselm Mueller
  • Patent number: 10571425
    Abstract: A disposable electrochemical test sensor designed to facilitate sampling of fluid samples. It has a fluid chamber having a novel extra wide sampling entrance, but no additional air escape vent. The chamber provides a reservoir from which a sample fluid can be drawn into the chamber through capillary action. The sampling entrance provided can draw fluid into the chamber through any part of the opening, allowing easy targeting the samples with small volume, picking up smeared samples, and added tolerance to users who jam the tip of the sensor into users' finger. The sampling entrance also serves as air escape vent. Such one opening sensor alleviates over-flow issue often encountered in convenient sensors.
    Type: Grant
    Filed: February 12, 2019
    Date of Patent: February 25, 2020
    Assignee: Changsha Sinocare Inc.
    Inventors: Hongli Che, Shaobo Li
  • Patent number: 10527576
    Abstract: A disposable electrochemical test sensor designed to facilitate sampling of fluid samples. It has a fluid chamber having a novel extra wide sampling entrance, but no additional air escape vent. The chamber provides a reservoir from which a sample fluid can be drawn into the chamber through capillary action. The extra wide sampling entrance provided by the present invention can draw blood into the chamber through any part of the opening, thus it allows easy targeting the samples with small volume, picking up smeared samples and it is more tolerant to users who jam the tip of the sensor into users' finger.
    Type: Grant
    Filed: August 23, 2018
    Date of Patent: January 7, 2020
    Assignee: Changsha Sinocare Inc.
    Inventors: Xiaohua Cai, Hongli Che, Shaobo Li
  • Patent number: 10359438
    Abstract: The present invention lies in the field of automated analyzers and relates to an automated warning system for potentially erroneous measurement results, which may be caused by the loss of a liquid container during a transport process.
    Type: Grant
    Filed: March 15, 2017
    Date of Patent: July 23, 2019
    Assignee: Siemens Healthcare Diagnostics Products GmbH
    Inventors: Daniel Heppner, David Solbach, Christian Verhalen
  • Patent number: 10001501
    Abstract: Described herein are automated and customizable sample preparation and analysis systems for detection and quantification of biomarkers (e.g., metabolites and/or lipids) in biological samples (e.g., blood, serum, or plasma) in a clinical setting. The automated systems are controlled by scripts that integrate communication between the components of the sample preparation system. Also described herein are mass spectrometry-based analytical methods featuring efficient system calibration and sample analysis that provide for accurate quantification of a set of markers in biological samples. The methods are capable of automatic high sample throughput in a clinical setting for detection and quantification using a mass spectrometry system and high performance liquid chromatography column.
    Type: Grant
    Filed: December 30, 2016
    Date of Patent: June 19, 2018
    Assignee: Universal Diagnostics, S. L.
    Inventors: Marko Bitenc, Kristi Kruusmaa, Paola Hurtado Castillo, Ana María Jiménez Girón, Rosa Argamasilla Martinez, Andreu Fabregat Rossell, Antonio Jesus Adsuar Gomez, Juan Martinez-Barea, Christian Hense, Patricia Rodríguez Gómez
  • Patent number: 9939455
    Abstract: A laboratory sample distribution system and to a laboratory automation system comprising a printed circuit board arrangement and a coil are presented. The printed circuit board arrangement and the coil are configured such that assembly and maintenance of the laboratory automation system are greatly simplified.
    Type: Grant
    Filed: February 17, 2017
    Date of Patent: April 10, 2018
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Hans Schneider, Christian Riether
  • Patent number: 9889448
    Abstract: A thermal cycling device for performing nucleic acid amplification on a plurality of biological samples positioned in a sample well tray. The thermal cycling device includes a sample block assembly, an optical detection system, and a sample well tray holder configured to hold the sample well tray. The sample block assembly is adapted for movement between a first position permitting the translation of the sample well tray into alignment with sample block assembly, and a second position, upward relative to the first position, where the sample block assembly contacts the sample well tray. A method of performing nucleic acid amplification on a plurality of biological samples positioned in a sample well tray in a thermal cycling device is also provided.
    Type: Grant
    Filed: March 2, 2015
    Date of Patent: February 13, 2018
    Assignee: APPLIED BIOSYSTEMS, LLC
    Inventor: Donald R. Sandell
  • Patent number: 9194877
    Abstract: The present invention provides systems and methods for analysis of samples, particularly biological and environmental sample to detect biomolecules of interest contained therein. A variety of system components are described herein, including, but not limited to, components for sample handling, mixing of materials, sample processing, transfer of materials, and analysis of materials. The invention further provides mechanisms for combining and integrating the different components and for housing, moving, and storing system components or the system as a whole. The systems may include any one or more or all of these components. The system finds particular use when employed for analysis of nucleic acid molecule using mass spectrometry, however, the invention is not limited such specific uses.
    Type: Grant
    Filed: July 15, 2010
    Date of Patent: November 24, 2015
    Assignee: IBIS BIOSCIENCES, INC.
    Inventors: Steven A. Hofstadler, Jose R. Gutierrez, James C. Hannis, Jared J. Drader, Rex O. Bare, Jeffrey C. Smith, Paul J. Gleason, Jared Nathanson, Ronald K. Bergold, Robert D. Miller, Kevin S. Oberkramer
  • Patent number: 9187725
    Abstract: An automatic biological sample purification apparatus is disclosed. The apparatus is equipped with a magnetic field applying part, in which the magnetic field applying part for purifying biological samples and a heating part are integrally formed with each other so as to be movable up and down. A method of extracting a target substance from the biological sample using the automatic biological sample purification apparatus equipped with the magnetic field applying part is also disclosed.
    Type: Grant
    Filed: April 29, 2011
    Date of Patent: November 17, 2015
    Assignee: BIONEER CORPORATION
    Inventors: Han-Oh Park, Jong-Kab Kim, Yang-Won Lee, Jong-Hoon Kim
  • Patent number: 9029159
    Abstract: A method of operating the automated sample workcell for processing one or more biological samples is presented. The method comprises receiving one or more biological samples. Each biological sample is contained in a sample tube. Each sample tube is a tube type. If a test order was received for at least one of the biological samples, the test order being indicative of one or more first processing steps, the workcell can automatically execute the one or more first processing steps. If the test order was not received, one or more second processing steps can be determined based on the tube type of the sample tube that contains the at least one biological sample and the one or more second processing steps can then be executed.
    Type: Grant
    Filed: April 12, 2012
    Date of Patent: May 12, 2015
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Frederic Furrer, Joerg Haechler, Andrzej Knafel
  • Publication number: 20150111198
    Abstract: A medical analysis method uses a medical analysis machine provided with a poly-articulated robot (70) comprising joints defining at least six axes of rotation (A1, A2, A3, A4, A5, A6) and adapted for spacing and/or orienting a terminal member (66) according to six degrees of freedom, the terminal member bearing a grasping member (78) adapted for grasping a container (16). The medical analysis method comprises at least the succession of steps consisting of providing a container (16) containing a sample to be treated stemming from a human being or an animal, transferring said container (16) towards at least one treatment station of the medical analysis machine (100) by means of the poly-articulated robot, treating the sample in a treatment station, transferring the container towards a station for capturing images, and displaying the treatment results through a user interface.
    Type: Application
    Filed: March 8, 2013
    Publication date: April 23, 2015
    Inventors: Jean-Michel Brisebat, Sébastien Bernay, Cédric Gagnepain, Daniel Seydoux
  • Patent number: 8968657
    Abstract: The transport and handling retention member comprises an adapter ring which has a central opening for receiving a tubular container for receiving samples, a gripping member for gripping the adapter ring, and a transfer head which can be moved between a rest position and an operating position, the transfer head in the operating position coming into operational contact with a tubular container which is received in the adapter ring.
    Type: Grant
    Filed: September 23, 2011
    Date of Patent: March 3, 2015
    Assignee: LCTech GmbH
    Inventors: Martin Brandlhuber, Uwe Aulwurm
  • Patent number: 8956569
    Abstract: A sample testing system comprising: a transporting apparatus; a testing apparatus for obtain a sample and performing testing on the obtained sample; and a controller. The controller executes operation of: controlling the transporting apparatus so as to transport the sample rack in first direction, such that each sample container held in a sample rack is transported to a obtaining position on which the testing apparatus obtains a sample and then the sample rack is transported toward the second position; changing, when retesting of a sample contained in a sample container is necessary, the transporting direction from the first direction to second direction, and then controlling the transporting apparatus so as to transport the sample container accommodating the sample, for which retesting is necessary, to the obtaining position again. Sample testing method and a computer program product are also disclosed.
    Type: Grant
    Filed: December 22, 2009
    Date of Patent: February 17, 2015
    Assignee: Sysmex Corporation
    Inventors: Yuichi Hamada, Daigo Fukuma
  • Patent number: 8940540
    Abstract: A portable, hand-held glucose testing device includes a housing configured to accommodate a plurality of test sensors in a stacked arrangement and having a wall with an opening defined therein. A plurality of packaged test sensors is stacked in alignment with one another within the housing. Each of the test sensors is packaged within a blister package. The blister package includes a blister package housing and a cover foil overlying a surface of the blister package housing and the test sensor. A drive slide is configured to displace one of the plurality of packaged test sensors out of alignment with other packaged test sensors. A knife mechanism is configured to pierce through the cover foil, and to engage and urge the test sensor to extend through the opening for receiving a sample. A meter contact is configured to engage the test sensor when the test sensor extends through the opening.
    Type: Grant
    Filed: March 12, 2013
    Date of Patent: January 27, 2015
    Assignee: Bayer HealthCare LLC
    Inventors: Steven C. Charlton, Allen Brenneman
  • Patent number: 8926903
    Abstract: To perform accurate measurement in the analysis of chemical components with low concentration, pretreatment such as concentration and purification of samples is essential. For high-throughput of pretreatment of biological samples, various random clinical testing is encountered, where analytes change from sample to sample. The pretreatment apparatus has a separating agent selectively separating a specific component by allowing a sample solution to flow therethrough. A holding section holds a plurality of housing sections, which house the separating agent therein, and has an endless track. A pressurizing section applies pressure to the housing section in a continuous and random-accessible manner; and an extraction solution receiver mechanism selectively receives an extracted solution from the separating agent housed in the housing section. A mass spectrometer is that can be connected to the pretreatment apparatus. Thus, a large number of specimens can be simultaneously processed.
    Type: Grant
    Filed: July 8, 2009
    Date of Patent: January 6, 2015
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Makoto Nogami, Katsuhiro Kanda, Izumi Waki
  • Publication number: 20150004640
    Abstract: This analysis apparatus includes a transporter transporting the specimens to the first measurement unit and the second measurement unit, and a control portion so controlling the transporter as to transport a first specimen container, stored in the rack, storing a first specimen to the first measurement unit and as to transport a second specimen container, stored in the rack along with the first specimen container, storing a second specimen to the second measurement unit.
    Type: Application
    Filed: September 17, 2014
    Publication date: January 1, 2015
    Applicant: Sysmex Corporation
    Inventors: Takaaki Nagai, Yuichi Hamada, Masaharu Shibata
  • Patent number: 8921094
    Abstract: A system and method for the processing of nucleic acids containing fluids involving manipulation of magnetically responsive particles contained therein are disclosed. In the system, a holder holds a plurality of containers containing the fluids, a heating device applies thermal energy to the fluids for incubation, and a separating device magnetically separates the particles. The heating and separating devices move into at least one operative position for processing the fluids and at least one inoperative position with respect to the containers, in which the containers are kept stationary at least during and in-between incubating the fluids and manipulating the magnetically responsive particles.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: December 30, 2014
    Assignee: Roche Molecular Systems, Inc.
    Inventors: Reto Keller, Thomas Meyer
  • Patent number: 8916096
    Abstract: According to an embodiment of the disclosure, the analyzer includes a reagent driving disk that accommodates a reagent configured for analysis and that transports the reagent to a desired position, and a fixed disk that has a reagent stand-by position in which to make a reagent container containing the reagent, temporarily stand by, and a magnetic particles stirring position for stirring magnetic particles. A portion of the reagent stand-by position is constituted by a loading system. A reagent container moving unit moves reagent containers containing the reagent, between the reagent driving unit and the fixed disk, according to analytical request status. Providing in a part of the fixed disk the loading system constructed so that reagent containers containing the reagent can be mounted therein during operation enables changing of reagent containers, irrespective of an operational status of the reagent driving disk, and the system to having cold-storage functionality.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: December 23, 2014
    Assignee: Hitachi High-Technologies Corporation
    Inventors: Yukinori Sakashita, Katsuaki Takahashi, Susumu Sakairi, Taku Sakazume, Yoshihiro Yamashita
  • Patent number: 8859289
    Abstract: A method and laboratory system for handling sample tubes and an image analyzing unit are disclosed. An incoming primary rack (PR) containing sample tubes (S) is transferred to an image analyzing unit (310). Geometry parameters of at least one sample tube contained in the primary rack are determined by means of image analyzing and compared with predetermined geometry criteria. If the sample tube's geometry fulfils the criteria, the sample tube is categorized as system conform and removed from the primary rack with a gripper for further processing; otherwise it is categorized as non-system conform and entered into error processing.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: October 14, 2014
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Christian Marty, Markus Rinderknecht
  • Publication number: 20140295563
    Abstract: There is provided an analyzer capable of stably supplying the cuvettes even if a great number of cuvettes is input to the storage section without thinking. The analyzer includes a storage section configured to store the plurality of input cuvettes, a take-out section configured to take out the cuvettes in the storage section from the storage section, and a vibration unit configured to vibrate the storage section to stimulate movement of the cuvettes in the storage section.
    Type: Application
    Filed: March 26, 2014
    Publication date: October 2, 2014
    Applicant: Sysmex Corporation
    Inventor: Hiroyuki MATSUURA
  • Publication number: 20140295562
    Abstract: Disclosed is a sample analyzer, comprising: a container storage configured to store a plurality of reagent containers; a setting chamber including within a setting portion on which at least one reagent container is set; a container detector for detecting the reagent container on the setting portion; a gate to open and close an entrance of the setting chamber; a transferring section configured to hold the reagent container on the setting portion and transfer it to the container storage; and a controller programmed to initiate the transferring section to transfer the reagent container from the setting portion to the container storage if the reagent container is set on the setting portion when the entrance of the setting chamber is closed by the gate.
    Type: Application
    Filed: December 20, 2013
    Publication date: October 2, 2014
    Applicant: Sysmex Corporation
    Inventors: Yuji WAKAMIYA, Tomohiro OKUZAKI
  • Publication number: 20140287516
    Abstract: A diagnostic analyzer includes a track, a light-blocking member, a motor, and an optical testing device. The track moves a reaction vessel held by the track. The light-blocking member is disposed adjacent to the track. The light-blocking member moves from a first position apart from the track to a second position closer to the track. When the light-blocking member is disposed in the first position a sample contained within the reaction vessel held by the track is exposed to light. When the light-blocking member is disposed in the second position the sample contained within the reaction vessel held by the track is blocked from exposure to the light. The motor moves the light-blocking member between the first and the second positions. The optical testing device is disposed adjacent to the track for optically testing the sample contained within the reaction vessel held by the track when the at least one light-blocking member is disposed in the second position.
    Type: Application
    Filed: March 14, 2014
    Publication date: September 25, 2014
    Inventor: Joseph P. Donohue
  • Publication number: 20140234978
    Abstract: A laboratory sample distribution system is presented. The laboratory sample distribution system comprises a plurality of container carriers. The container carriers each comprise at least one magnetically active device such as, for example, at least one permanent magnet, and carry a sample container containing a sample. The system further comprises a transport plane to carry the multiple container carriers and a plurality of electro-magnetic actuators stationary arranged below the transport plane. The electro-magnetic actuators move a container carrier on top of the transport plane by applying a magnetic force to the container carrier. The system also comprises at least one transfer device to transfer a sample item, wherein the sample item is a container carrier, a sample container, part of the sample and/or the complete sample, between the transport plane and a laboratory station such as, for example, a pre-analytical, an analytical and/or a post-analytical station.
    Type: Application
    Filed: April 28, 2014
    Publication date: August 21, 2014
    Applicant: Roche Diagnostics Operations, Inc.
    Inventors: Michael Heise, Hans Schneider
  • Publication number: 20140170636
    Abstract: A method and an automated system for testing liquid samples comprising a reaction vessel transferring device are presented. A first analytical unit for running a first diagnostic test comprises a rotatable first vessel holder detachably holding reaction vessels. A second analytical unit for running a second diagnostic test comprises a stationary linear second vessel holder detachably holding reaction vessels. The transferring device comprises a gripper for gripping a reaction vessel and transfers reaction vessels from the first vessel holder to the second vessel holder and/or vice versa. The device is translatable parallel to the second vessel holder and the gripper moves along a curved path between a picking position and a reaction vessel seat of the second vessel holder.
    Type: Application
    Filed: December 11, 2013
    Publication date: June 19, 2014
    Applicant: ROCHE DIAGNOSTICS OPERATIONS, INC.
    Inventors: Marco Bucher, Gottlieb Schacher
  • Patent number: 8741219
    Abstract: A sample processing system comprising: a transporting apparatus for transporting a sample; a plurality of sample processing apparatuses, arranged along a direction in which the sample is transported by the transporting apparatus, for processing the sample transported by the transporting apparatus; a base on which at least one of the sample processing apparatuses is placed; and a movement restricting section for restricting, on the base, a movement area within which the sample processing apparatus moves, wherein the movement restricting section allows the sample processing apparatus to move on the base so as to change orientation of the sample processing apparatus, is disclosed. A base for a sample processing system and a sample processing apparatus are also disclosed.
    Type: Grant
    Filed: December 15, 2009
    Date of Patent: June 3, 2014
    Assignee: Sysmex Corporation
    Inventors: Yuichi Hamada, Keisuke Kuwano
  • Publication number: 20140147922
    Abstract: A device for positioning vessels, with a holder for vessels, comprising a series of receptacles arranged on a circular line, for a circular ring-shaped vessel chain, a central area, arranged within the series of receptacles, and having further receptacles for single vessels containing reagents, and means for aligning, and with a carrier for single vessels, which comprises a holding plate in the form of a circular disc or of a part of a circular disc, which has holes for single vessels at certain positions, and which has at least one further means for aligning the carrier to the means for aligning the holder in a certain position, wherein in this position, the holes are aligned to certain further receptacles, the remaining further receptacles are covered up by the holding plate, and single vessels filled with reaction liquid can be inserted into the holes and into the further receptacles aligned thereto.
    Type: Application
    Filed: May 30, 2012
    Publication date: May 29, 2014
    Applicant: Eppendorf AG
    Inventors: Helmut Knofe, Jens-Peter Kroog, Judith Lucke
  • Publication number: 20140141518
    Abstract: The invention relates to a reagent station (1) for an automated analysis device, comprising a first and a second reagent container storage (2, 10) and a transfer apparatus (20) which transfers reagent containers (16) between the first and the second reagent container storage (2, 10). Furthermore, the invention relates to a method for loading an automated analysis device with reagent containers.
    Type: Application
    Filed: November 11, 2013
    Publication date: May 22, 2014
    Applicant: SIEMENS HEALTHCARE DIAGNOSTICS PRODUCTS GMBH
    Inventor: Holger Pufahl
  • Patent number: 8728396
    Abstract: The present invention is a sample analyzer including: a first and a second measurement unit configured to measure a sample accommodated in a sample container; a rack transport unit configured to transport each of a plurality of sample containers held in a sample rack to either the first or the second measurement unit; and a controller configured to acquire a measurement item information indicating a measurement item of each of samples accommodated in the plurality of sample containers held in the sample rack, determine a sample container to be a transport object and a measurement unit to be a transport destination of the sample container based on the acquired plurality of measurement item information, and control the rack transport unit to transport the sample container determined as the transport object to the measurement unit determined as the transport destination.
    Type: Grant
    Filed: March 9, 2011
    Date of Patent: May 20, 2014
    Assignee: Sysmex Corporation
    Inventors: Keisuke Kuwano, Daigo Fukuma
  • Patent number: 8721965
    Abstract: A transporting apparatus for transporting a specimen rack holding a specimen container containing a specimen, comprising: an engage unit capable of engaging with the specimen rack; and a moving mechanism for moving the engage unit in a transport direction of the specimen rack, the transport direction including a first direction and a second direction opposite to the first direction, wherein the engage unit comprises: a pair of engage members, capable of mutually approaching and separating relative to the transport direction, and engaging with the specimen rack gaplessly relative to the transport direction by the approaching operation or the separating operation; and a driver for driving the pair of engage members so as to perform the approaching operation and the separating operation. A specimen analyzing apparatus is also disclosed.
    Type: Grant
    Filed: November 16, 2009
    Date of Patent: May 13, 2014
    Assignee: Sysmex Corporation
    Inventor: Hiroki Koike
  • Patent number: 8703492
    Abstract: An automated sample processing system having a sample input adapted to simultaneously receive a number of sample containers, a reagent input adapted to receive one or more new reagent supplies, a consumable input adapted to receive one or more new consumable supplies, a solid waste output adapted to receive used consumable supplies, a liquid waste output adapted to receive one or more used reagent supplies, and a processing center. The processing center includes a decapper adapted to remove a lid from at least one sample container, an aspirator adapted to remove a specimen from the at least one sample container and transfer the specimen to an output vessel, and a capper adapted to replace the lid on the at least one sample container.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: April 22, 2014
    Assignee: Qiagen Gaithersburg, Inc.
    Inventors: Brian Austin Self, Jonathan Matthew Miller, Carl Theodore Edens
  • Patent number: 8703054
    Abstract: The present invention relates to analytical apparatus comprising: a passage (45) in which an analytical tool (2) is moved from above to below; and a movement block (51), made capable of reciprocatory movement in the horizontal directions (D1, D2), for moving the analytical tool (2) incoming through the passage (45) in the direction (D1). This analytical apparatus is constructed such that, by erecting the analytical tool (2) on the movement block (51) positioned directly below the outlet (45B) of the passage (45) and causing the movement block (51) to move in the D1 or D2 direction, the analytical tool (2) is tipped over, and the analytical tool (2) is placed in a horizontal condition on the movement block (51).
    Type: Grant
    Filed: June 1, 2005
    Date of Patent: April 22, 2014
    Assignee: ARKRAY, Inc.
    Inventor: Hidenari Yamagata
  • Patent number: 8663557
    Abstract: An analyzers that comprise a container holder for placing containers; a detector for detecting whether or not a container is placed at the container holder; a controller for acquiring the status of the container holder based on the output of the detector; and a display for displaying the status of the container holder is disclosed.
    Type: Grant
    Filed: January 19, 2005
    Date of Patent: March 4, 2014
    Assignee: Sysmex Corporation
    Inventors: Eiji Tanoshima, Yuuji Wakamiya
  • Patent number: 8657550
    Abstract: A crucible handling shuttle includes a pair of opposed dual crucible-gripping arms mounted on a rotatable head. The shuttle is removably plugged into a sliding block of a carriage to move between a furnace and a crucible loading station. The carriage includes mechanical, electrical, and pneumatic plugs or sockets which couple to mating sockets or plugs of the shuttle. A linear actuator extends between the carriage and the furnace base to raise and lower the carriage and shuttle coupled thereto.
    Type: Grant
    Filed: February 23, 2011
    Date of Patent: February 25, 2014
    Assignee: Leco Corporation
    Inventors: Gordon C. Ford, Raghu Murthy
  • Publication number: 20140038298
    Abstract: A method of nondisruptive loading of reagents in a body fluid workstation comprising a plurality of analyzers includes: receiving application information input from a user to an analyzer which needs loading of a reagent; controlling the analyzer to pause dispensing of a reagent at a determined time; and controlling one or more other analyzers in the body fluid workstation to continue testing.
    Type: Application
    Filed: October 15, 2013
    Publication date: February 6, 2014
    Inventors: Huaibo Yu, Qiao Zou
  • Patent number: 8641969
    Abstract: The present invention is to present a sample testing apparatus comprising: a transport unit for transporting a sample container through a first position and a second position; a testing unit for performing a test on the sample in the sample container transported to the first position; a determination result obtainer for obtaining one of a first determination result indicating that a second test is required and a second determination result indicating that the second test is not required; and a transport controller for controlling the transport unit so as to transport the sample container back to the first position, if the first determination result has been obtained, wherein the sample container is not transported beyond the second position from the first position side before any one of the first and the second determination result has been obtained.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: February 4, 2014
    Assignee: Sysmex Corporation
    Inventors: Nobuhiro Kitagawa, Hiroyuki Tanaka, Hiroo Tatsutani, Tomoyuki Asahara
  • Patent number: 8580195
    Abstract: A laboratory system for handling sample tube racks, an alignment element for sample tube racks and a rack tray receiver assembly are disclosed. The laboratory system to handle laboratory sample tube racks comprises a robotic arm (220) with a gripper (222) for gripping primary racks (PR), wherein the primary racks (PR) to be handled comprise a first end surface (76) and a second end surface (78), the first end surface (76) having a first surface geometry and the second end surface (78) having a second surface geometry, and wherein the gripper (222) comprises a first gripping arm (226) and a second gripping arm (228), with the first gripping arm (226) having a gripping surface being complementary to the first surface geometry, and the second gripping arm (228) having a gripping surface being complementary to the second surface geometry.
    Type: Grant
    Filed: July 23, 2009
    Date of Patent: November 12, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Rolf Frey, Fritz Goedl, Bruno Koch, Joachim Lackner, Beat Widmer, Lydia Stettler
  • Patent number: 8492155
    Abstract: An automated immunoassay apparatus is disclosed comprising a single optical reading device (2a, 2b) for reading two microtitre plates (9, 14). A first microtitre plate (9) is loaded into an upper plate holder (8) which is linearly translated at a fixed height. A second microtitre plate (14) is loaded into a lower plate holder (13). The lower plate holder (13) runs along a contoured track which varies the vertical height of the second microtitre plate (14).
    Type: Grant
    Filed: November 10, 2006
    Date of Patent: July 23, 2013
    Assignee: Dynex Technologies, Inc.
    Inventors: Adrian Bunce, Andrew Fusellier
  • Publication number: 20130130390
    Abstract: An automated chemistry analysis method is disclosed. In one general aspect, the method includes receiving a modular chemistry analysis test unit that includes one or more vessels for one or more reagents, and a machine-readable test specification coupled with the vessels. The method also includes defining a test that defines a test including a series of operations that employ the reagents for the vessels, and installing the chemistry analysis test unit in a first chemistry analyzer that includes one or more analysis tools and sequencing logic for sequencing instructions to be carried out by the analysis tools. The machine-readable test specification is automatically received from the chemistry analysis test module and stored for access by the sequencing logic to allow the sequencing logic to instruct the analysis tools to carry out the test defined by the test specification.
    Type: Application
    Filed: September 14, 2012
    Publication date: May 23, 2013
    Inventors: Jeannine Dussi, Edward Ganshirt, Ray Goodwin, Stan Liffmann, Tony Mao, Doug Moe, Steve Rettew, Ian Smith, Charlene Soley, Le Nguyen, Qian Sun, Will Whelan, Diana Zipeto, Gregory Sweetser
  • Patent number: 8431079
    Abstract: Embodiments of an analyzer for performing medical diagnostic analysis of biological samples are disclosed. In one embodiment, the analyzer may have a first and at least a second disk-shaped cuvette conveyor each having an array of cuvette holders, a first drive unit for rotating the first cuvette conveyor about a rotation axis, and a second drive unit for rotating the second cuvette conveyor about the rotation axis. The operation of the second drive unit is independent from the operation of the first drive unit. The first cuvette conveyor and the second cuvette conveyor are spaced from each other in an axial direction along the rotation axis and with an air gap between them. The cuvette holders of the first cuvette conveyor and the cuvette holders of the second cuvette conveyor are adapted for holding cuvettes having the same shape and dimensions.
    Type: Grant
    Filed: November 30, 2010
    Date of Patent: April 30, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Burkard Rosenberg, Juergen Rauh
  • Patent number: 8394637
    Abstract: The invention relates to a handheld analyzer for testing a sample, in particular of a biological fluid, for a medically significant component. It comprises a test unit, which detects the correct positioning of an analytical consumable means in a conveyance pathway. According to this invention, the test unit has both an electric switch component which mechanically senses the positioning of the analytical consumable means and an optical sensor unit which optically senses the positioning of the analytical consumable means on the conveyance pathway. The handheld analyzer is controlled as a function of a comparison of the signals of the electric switch component and the optical sensor unit. It is possible in this way to reduce malfunctions or operating errors associated therewith.
    Type: Grant
    Filed: June 2, 2008
    Date of Patent: March 12, 2013
    Assignee: Roche Diagnostics Operations, Inc.
    Inventors: Jochen Schulat, Gertrud Albrecht, Bernhard Kern
  • Patent number: 8377377
    Abstract: An automated microscope slide staining system and staining apparatus and method that features a plurality of individually operable miniaturized pressurizable reaction compartments or a pressurizable common chamber for individually and independently processing a plurality of microscope slides. The apparatus preferably features independently movable slide support elements each having an individually operable heating element.
    Type: Grant
    Filed: August 28, 2009
    Date of Patent: February 19, 2013
    Inventor: Lee H. Angros
  • Patent number: 8357538
    Abstract: An automated assay processing method including transferring a first number of samples from respective sample containers to a first intermediary vessel, determining the testing adequacy of a second number of samples in a second intermediary vessel, preparing a third number of samples in a third intermediary vessel for downstream testing; and transferring a fourth number of samples from a fourth intermediary vessel to an output sample tray. These steps are all performed essentially simultaneously within the duration of a single clock cycle and are repeated during one or more subsequent clock cycles. The clock cycle may be relative to each intermediary vessel. The clock cycle also may be universal to the first, second, third and fourth intermediary vessels.
    Type: Grant
    Filed: October 9, 2009
    Date of Patent: January 22, 2013
    Assignee: Qiagen Gaithersburg, Inc.
    Inventors: Brian Austin Self, Fei Yin, Carl Theodore Edens
  • Patent number: 8343770
    Abstract: An analyzer comprising: a specimen container setting portion including a plurality of container holders for holding a plurality of specimen containers of different types; an aspiration section for aspirating the specimen from the specimen container set in the specimen container setting portion; a sensor for detecting the presence of the specimen container set in at least one of the plurality of container holders; and a controller for determining in which of the plurality of container holders the specimen container is set based on the detection result of the sensor, and controlling the operation of the aspiration section, is disclosed. A method for aspirating a specimen is also disclosed.
    Type: Grant
    Filed: March 6, 2009
    Date of Patent: January 1, 2013
    Assignee: Sysmex Corporation
    Inventors: Yuichi Hamada, Daigo Fukuma
  • Patent number: 8298498
    Abstract: An apparatus and method of loading reagent in a specimen handling device is disclosed, where the apparatus includes a deck with a plurality of positions defined thereon and each of the positions visually marked by a distinct one of a first set of icons. Each of a plurality of trays is removably securable to a selected one of the positions on the deck and includes the distinct one of the first set of icons visually marking the selected one of the positions. Reagent receptacles on each of the plurality of trays are visually marked by a distinct one of a second set of icons, and a kit is provided with a plurality of containers with selected reagents therein, each of the containers being visually marked by the distinct one of the second set of icons visually marking the receptacle into which that reagent is to be poured. The fluids including specimen samples and reagents are moved between tubes during processing without directly passing over tubes which the reagents could contaminate.
    Type: Grant
    Filed: July 21, 2006
    Date of Patent: October 30, 2012
    Assignee: Abbott Laboratories
    Inventors: Scott Safar, Stephen Herchenbach
  • Patent number: 8262994
    Abstract: An analyzer comprising: a first specimen holder configured to hold a plurality of first specimen containers; a conveying assembly for conveying the first specimen containers held in the first specimen holder; a second specimen holder arranged at a position higher than an upper end of the first specimen containers held in the first specimen holder; a holder moving assembly for moving the second specimen holder so as to pass the upper side of at least one of the first specimen containers held in the first specimen holder; a container transferring assembly for transferring at least one of the first specimen containers from the first specimen holder to the second specimen holder; and a controller for controlling the holder moving assembly and the container transferring assembly, is disclosed.
    Type: Grant
    Filed: December 13, 2011
    Date of Patent: September 11, 2012
    Assignee: Sysmex Corporation
    Inventors: Yuichi Hamada, Masaharu Shibata, Daigo Fukuma