Dosage Determination Of High Energy Radiation, (e.g., Use Of An X-ray Dosimeter, Etc.) Patents (Class 436/58)
  • Patent number: 5599716
    Abstract: A process for the measurement of the level of radioactivity of a solid by contacting the solid with a chemically stable reactant fluid. The reactant fluid is converted by nuclear radiation to a chemically stable product fluid to an extent dependent upon the radioactive content of the solid. The amount of the reactant fluid converted into the product fluid is detected in order to determine the level of radioactivity of the solid.
    Type: Grant
    Filed: November 27, 1995
    Date of Patent: February 4, 1997
    Assignee: British Nuclear Fuels plc
    Inventor: Robert G. G. Holmes
  • Patent number: 5424211
    Abstract: A composition for detecting the presence and concentration of a substance such as uranyl, comprising an organohalide covalently bonded to an indicator for said substance. The composition has at least one active OH site for forming a complex with the substance to be detected. The composition is made by reacting equimolar amounts of the indicator and the organohalide in a polar organic solvent. The absorbance spectrum of the composition-uranyl complex is shifted with respect to the absorbance spectrum of the indicator-uranyl complex, to provide better spectral resolution for detecting uranyl.
    Type: Grant
    Filed: May 16, 1994
    Date of Patent: June 13, 1995
    Assignee: The United States of America as represented by the United States Department of Energy
    Inventors: Lewis C. Baylor, Susan M. Stephens
  • Patent number: 5420000
    Abstract: Described is a radiation sensitive imaging film containing a heat fixable radiation sensitive element, e.g., a diacetylene, of the formula: R--C.tbd.C--C.tbd.C--R', where R and R' are, e.g., both --CH.sub.2 --O--CONH--(CH.sub.2).sub.5 CH.sub.3. After exposure to X-radiation during diagnostic or X-ray therapy, the resulting image can be permanently dry fixed by a short heating step and then stored for a long period. Processes for making the film, new binder-convertor systems, and a device incorporating the film are described as well as other imaging, diagnostic and therapeutic methods utilizing the film in high energy radiation applications in the health care field.
    Type: Grant
    Filed: August 12, 1993
    Date of Patent: May 30, 1995
    Assignee: JP Laboratories, Inc.
    Inventors: Gordhanbhai N. Patel, Yao-Ming Cheng, Subhash H. Patel
  • Patent number: 5346814
    Abstract: A method of assessing a cell's susceptibility to cell-damaging energy, such as ionizing radiation and heat, is disclosed. The method is based on measurable changes in voltage-dependent potassium channel currents in the cell in response to the energy. Also disclosed is a method for screening drugs which are effective to sensitize a cell to cell-damaging radiation.
    Type: Grant
    Filed: October 14, 1992
    Date of Patent: September 13, 1994
    Assignee: Board of Trustees of the Leland Stanford Jr. University
    Inventors: George M. Hahn, Alie H. Saad, Amato J. Giaccia
  • Patent number: 5288695
    Abstract: A process for determining an end member age of an illite component in an earth sample which contains a diagenetic illite component and a detrital illite component. As a first step, the sample is separated into a plurality of fractions so that the fractions will have different mean ages of illite. Next, the relative percentage of one of the illite components is determined for each fraction. The mean age of total illite in each fraction is determined using potassium-argon age analysis. The determined relative percentages are then correlated with the determined mean ages to generate a linear relationship. The end member age for each illite component can then be determined by using the linear relationship since zero percent of one of the illite components corresponds to the end member age of the other illite component.
    Type: Grant
    Filed: October 2, 1992
    Date of Patent: February 22, 1994
    Assignee: Exxon Production Research Company
    Inventor: David R. Pevear
  • Patent number: 5206174
    Abstract: A spectroscopic method to rapidly measure the presence of plutonium in soils, filters, smears, and glass waste forms by measuring the uranium L-shell x-ray emissions associated with the decay of plutonium. In addition, the technique can simultaneously acquire spectra of samples and automatically analyze them for the amount of americium and .gamma.-ray emitting activation and fission products present. The samples are counted with a large area, thin-window, n-type germanium spectrometer which is equally efficient for the detection of low-energy x-rays (10-2000 keV), as well as high-energy .gamma. rays (>1 MeV). A 8192- or 16,384 channel analyzer is used to acquire the entire photon spectrum at one time. A dual-energy, time-tagged pulser, that is injected into the test input of the preamplifier to monitor the energy scale, and detector resolution. The L x-ray portion of each spectrum is analyzed by a linear-least-squares spectral fitting technique. The .gamma.
    Type: Grant
    Filed: September 24, 1992
    Date of Patent: April 27, 1993
    Assignee: EG&G Idaho, Inc.
    Inventors: Robert J. Gehrke, Marie H. Putnam, E. Wayne Killian, Richard G. Helmer, Ronnie L. Kynaston, Scott G. Goodwin, Larry O. Johnson
  • Patent number: 5108891
    Abstract: An assay which is responsive to the levels of anti-p24 antibodies in serum samples is provided which comprises the steps of: (a) forming a test mixture comprising the sample and an antigen solution containing free p24 antigen within a predetermined concentration range: (b) incubating the test mixture under conditions whereby anti-p24 antibodies from the sample, if any, can react with the free p24 antigen to form antibody-antigen complexes; (c) determining the concentration of free p24 antigen remaining in the test mixture after the incubation; (d) determining the concentration of free p24 antigen in the antigen solution; and (e) calculating the difference between the concentration of free p24 antigen in the antigen solution and the concentration of freee p24 antigen in the test mixture after the incubation.The difference calculated in step (e) represents the "binding capacity" of the serum sample for p24 antigen.
    Type: Grant
    Filed: June 9, 1988
    Date of Patent: April 28, 1992
    Assignee: Beth Israel Medical Center
    Inventor: Thomas S. Croxson
  • Patent number: 4910149
    Abstract: A method and apparatus for detecting the presence of radiation are provided by making use of the change that occur in the electrical and optical properties of an electroconductive polymer which is exposed to radiation while in contact with doping gas. Said method and apparatus can be applied to the purpose of detection or determination of all radiations including electron beams, gamma-rays, alpha-rays and neutron rays.
    Type: Grant
    Filed: July 26, 1985
    Date of Patent: March 20, 1990
    Assignee: Sumitomo Electric Industries, Ltd.
    Inventors: Jiro Okube, Tomoyoshi Moriya, Katsumi Yoshino
  • Patent number: 4791155
    Abstract: An assembly for monitoring ionising radiation which comprises coated on a base a binder layer containing a polychlorinated hydrocarbon and a color former.The assembly can be used to monitor levels of radiation of from 0.1 MRads to 10.0 MRads.
    Type: Grant
    Filed: July 22, 1987
    Date of Patent: December 13, 1988
    Assignee: Ciba-Geigy AG
    Inventors: David P. Gregory, Bernard J. Dean, Stephen R. Postle
  • Patent number: 4508686
    Abstract: Apparatus and test film strip for evaluation of a film processor, particularly an x-ray film processor, based on a photodetector signal sequentially indicating the optical density of graded density test areas on a developed film and comparing the output thereof to a preselected voltage relating to the acceptable/too dark threshold of an unexposed or base fog area, the acceptable or too light threshold of a maximum density or dark area and the acceptable/too light and acceptable/too dark threshold of a medium density test area. Sequence testing of the graded density areas is functionally related on a single film strip to timing marks, adapted to be read by photodetector and timing circuitry, the timing marks and graded density test areas being linearly spaced and relatively disposed along the length of film strip.
    Type: Grant
    Filed: May 19, 1982
    Date of Patent: April 2, 1985
    Assignee: Probex, Inc.
    Inventors: Gary S. Shaber, Charles W. Buenzli, Jr.
  • Patent number: 4466941
    Abstract: A photosensitive composition is disclosed, which is capable of offering a visual, calibrated reaction to the presence of ultraviolet radiation. The composition comprises a complex of a leuco dye and animal-derived serum albumin. The preparation of this complex has been found to stabilize the leuco dyes, to avoid fading after the presentation of a color reaction upon exposure. Also, the leuco dye-serum albumin albumin complex is capable of exacting calibration, so that scientifically significant quantitative measurements of ultraviolet light exposure can be made. Moreover, the present composition eliminates the need for the addition to the leuco dye of various activator compounds, that are chemically unstable, e.g. volatile, or present potential exposure to toxicity, in the instance where personal applications for the photosensitive composition are contemplated.The present invention includes a method of preparing the photosensitive composition, including the preparation of an ultraviolet light indicator.
    Type: Grant
    Filed: February 11, 1982
    Date of Patent: August 21, 1984
    Assignee: Evreka, Inc.
    Inventors: Anthony Cerami, Michael A. Yamin
  • Patent number: 4430258
    Abstract: Method of producing liquid equivalent solid gamma ray calibration standards comprising the steps of adding a first organic solvent to a calibrated aqueous solution of radioactive material, either in the form of a single isotope or mixed isotopes, to form a first solution; mixing the first solution with a polymerizible resin dissolved in a second organic solvent together with a hardening catalyst to form a second solution; and curing the second solution. With isotope standards requiring highly acidic conditions, a stabilizing agent is added to the first solvent to complex with metal and hydrogen ions so as to prevent plate-out.
    Type: Grant
    Filed: May 28, 1981
    Date of Patent: February 7, 1984
    Inventors: Robert C. McFarland, Patricia A. McFarland
  • Patent number: 4389217
    Abstract: A recording device is described, useful as an integrated time-temperature or radiation-dosage history indicator. The device contains a substrate having deposited thereon at least two indicating units, one being unreacted and representing zero time of exposure and the other unit being pre-reacted. Each unit is comprised of an acetylenic compound containing at least one --C.tbd.C--C.tbd.C-- group, capable of reacting by 1,4-addition polymerization thereby forming an end-point color after an irreversible, progressive color change upon thermal annealing or exposure to actinic radiation. The end-point color represents an integrated time-temperature history of thermal annealing or radiation-dosage history. Each unit is constructed such that the time required to form the end-point color by thermal annealing at a given temperature or for a known thermal history, or exposure to actinic radiation at a given average radiation dosage rate, is predetermined.
    Type: Grant
    Filed: November 24, 1980
    Date of Patent: June 21, 1983
    Assignee: Allied Corporation
    Inventors: Ray H. Baughman, Gordhanbhai N. Patel, Granville G. Miller
  • Patent number: 4384980
    Abstract: A composition is described comprising at least two co-crystallized acetylenic compounds, of different chemical structures, each containing at least one --C.tbd.C--C.tbd.C-- group and substituents selected from the group consisting of sulfonate, urethane and alcohol radicals, at least one of the compounds capable of ungergoing a contrasting color change upon exposure to actinic radiation or thermal annealing, wherein the composition exhibits a substantially different thermogram than the sum of thermograms of the individual components as obtained by differential scanning alorimetry.A device is also described useful for measuring the time-temperature or radiation-dosage history of an article comprising a substrate having deposited thereon the described composition.A process is also described for producing the composition of this invention.
    Type: Grant
    Filed: November 13, 1978
    Date of Patent: May 24, 1983
    Assignee: Allied Corporation
    Inventor: Gordhanbhai N. Patel