Appetite Or Satiation Affecting Patents (Class 514/4.9)
  • AGENTS AND METHODS FOR MODULATING MACROPHAGE INHIBITORY CYTOKINE (MIC-1) ACTIVITY
    Publication number: 20100278843
    Abstract: The invention relates to a method and novel types of agents for modulating appetite and/or body weight in a subject. Moreover, the invention relates to a method of screening for agents which interact and modulate the activity of the receptor complex for macrophage inhibitory cytokine-1 (MIC-1).
    Type: Application
    Filed: August 18, 2008
    Publication date: November 4, 2010
    Inventors: Samuel Norbert Breit, David Alexander Brown, Herbert Herzog, Shu Lin
  • Method of Drug Formulation Based on Increasing the Affinity of Crystalline Microparticle Surfaces for Active Agents
    Publication number: 20100278924
    Abstract: Methods are provided for coating crystalline microparticles with an active agent by altering the surface properties of the microparticles in order to facilitate favorable association on the microparticle by the active agent. Type of surface properties that are altered by the disclosed methods include by electrostatic properties, hydrophobic properties and hydrogen bonding properties.
    Type: Application
    Filed: July 6, 2010
    Publication date: November 4, 2010
    Applicant: MANNKIND CORPORATION
    Inventors: Keith A. Oberg, Joseph Sulner
  • COMPOUND FOR CONTROLLING APPETITE
    Publication number: 20100272727
    Abstract: Insl5 has been found to be orexigenic, i.e. it increases appetite. Insl5, or a derivative or fragment thereof that retains the ability to bind to the GPR100 receptor, or an Insl5 antibody, are useful in therapy, in particular to treat anorexia nervosa, bulimia, cachexia or wasting disease.
    Type: Application
    Filed: September 5, 2008
    Publication date: October 28, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Johannes Grosse, Helen Heffron, Kate Day