Designated Inorganic Nonactive Ingredient Or Elemental Material Other Than Water Patents (Class 514/769)
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Publication number: 20110236497Abstract: Disclosed herein are compositions comprising cross-linkers for cross-linking a retention vehicle polymer. The compositions are particularly useful for local administration of a bioactive agent, wherein prolonged or extended availability of the bioactive agent at the site of administration is desired. Also disclosed are methods of delivering the compositions to a subject.Type: ApplicationFiled: March 29, 2011Publication date: September 29, 2011Inventors: Thomas R. Tice, Kevin W. Burton
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Publication number: 20110236492Abstract: The present invention is concerned with a refinement of the processing of particles that are to form a dry powder formulation which is to be administered to the lung using a dry powder inhaler (DPI) device. In particular, the present invention provides the processing of particles of active material and particles of carrier material in the presence of additive material to provide a powder composition which exhibits excellent powder properties and which is economical to produce.Type: ApplicationFiled: April 12, 2011Publication date: September 29, 2011Applicant: VECTURA LIMITEDInventor: David MORTON
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Publication number: 20110229527Abstract: An improved excipient comprising substantially homogeneous particles of a compressible, high functionality granular dibasic calcium phosphate based excipient is provided. The improved excipient comprises dibasic calcium phosphate, a binder and a disintegrant, and is formed by spraying a homogeneous slurry of the components. The improved excipient provides enhanced flowability/good flow properties, an increased API loading and blendability and higher compactibility as compared to the individual components, and as compared to excipients formed from the same materials by conventional methods. The improved excipient has strong intraparticle bonding bridges between the components, resulting in a unique structural morphology including significant open structures or hollow pores. The presence of these pores provides a surface roughness that is the ideal environment for improved blending with an API.Type: ApplicationFiled: November 13, 2009Publication date: September 22, 2011Inventors: Nandu Deorkar, James Farina, Liliana Miinea, Sameer Randive
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Publication number: 20110230353Abstract: A water-dispersible particle is provided that includes struvite in an amount ranging from 5% to 99.9% by weight of the total dry weight of the particle. A binder component is present in an amount from 1% to 95% by weight. The struvite and the binder component on that contact with water causes particle dispersion into more than 100 pieces. A process for making a water-dispersible particle includes mechanical aggregation of a struvite into a pellet. A binder component is present in the particle in an amount ranging from 1% to 95% by weight. The struvite and the binder component are present in a form such that contact with water causes particle dispersion into more than 100 pieces. The particle is then dried and ready to be applied.Type: ApplicationFiled: April 5, 2011Publication date: September 22, 2011Inventors: Charles W. Anderson, Timothy D. Birthisel
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Publication number: 20110218251Abstract: A product has solid stable water clusters including a plurality of water molecules connected with one another by electrical dipole interaction via internal electric field of ions and having a permanent electric dipole moment with an electrical field surrounding the solid stable water clusters.Type: ApplicationFiled: December 3, 2009Publication date: September 8, 2011Inventors: Shui Yin Lo, David Gann, Geng Xu
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Publication number: 20110218102Abstract: A water-dispersible particle is provided that includes organic origin potash in an amount ranging from 5% to 99.9% by weight of the total dry weight of the particle. A binder component is present in an amount from 1% to 95% by weight. The organic origin potash and the binder component on that contact with water causes particle dispersion into more than 100 pieces. A process for making a water-dispersible particle includes mechanical aggregation of the potash into a pellet. A binder component is present in the particle in an amount ranging from 1% to 95% by weight. The potash and the binder component are present in a form such that contact with water causes particle dispersion into more than 100 pieces. The pellet is then dried and ready to be applied.Type: ApplicationFiled: September 7, 2010Publication date: September 8, 2011Applicant: The Andersons, Inc.Inventors: Charles W. Anderson, Timothy D. Birthisel
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Publication number: 20110212163Abstract: The present invention generally relates to systems and methods for releasing a compound from an article using an external trigger, for example, magnetic fields. One aspect of the invention is generally directed to an article containing a magnetically-susceptible material. Exposure of the magnetically-susceptible material to a magnetic field, such as an oscillating magnetic field, may cause the magnetically-susceptible material to increase in temperature. This increase in temperature may be used, in some embodiments, to cause the release of a drug or other releasable material from the article. For instance, the drug may be contained in a heat-sensitive material in thermal communication with the magnetically-susceptible material, or the drug may be contained within an enclosure that is isolated, at least in part, by a heat-sensitive material in thermal communication with the magnetically-susceptible material. Other aspects of the invention are directed to systems and methods of making or using such articles, e.Type: ApplicationFiled: July 23, 2009Publication date: September 1, 2011Applicants: CHILDREN'S MEDICAL CENTER CORPORATION, MASSACHUSETTS INSTITUTE OF TECHNOLOGY, THE GENERAL HOSPITAL CORPORATION D/B/AInventors: Todd R. Hoare, Daniel S. Kohane, Robert S. Langer, Mikhail G. Shapiro, Yoon Yeo, Grace Y. Kim, Shahriar R. Khushrushahi
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Publication number: 20110206763Abstract: A rapid-release encapsulation composition that includes a gelatin and a water-insoluble rapid-release agent is provided. In particular, a rapid-release encapsulation composition that includes a gelatin and an insoluble carbonate salt is provided.Type: ApplicationFiled: February 18, 2011Publication date: August 25, 2011Applicant: GelitaInventors: Tom Keenan, John M. Dolphin
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Publication number: 20110196474Abstract: Compositions of matter comprising a magnetically sensitive drug carrier and a related drug as well as methods for administering these compositions and causing them to localize within the patient using an internal or external magnetic field are described.Type: ApplicationFiled: February 11, 2010Publication date: August 11, 2011Applicant: ABBOTT CARDIOVASCULAR SYSTEMS INC.Inventors: Dariush Davalian, Syed Faiyaz Ahmed Hossainy, Rachel Bright, Jinping Wan, Florian Niklas Ludwig
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Publication number: 20110189143Abstract: The present invention provides formulations and methods for preventing, suppressing, treating, or controlling pre- or post-harvest disease or decay in plants. In the inventive method, plants are contacted with a formulation including an antagonistic microorganism and a booster composition. The booster composition generally includes about 3 parts Kaolin clay, about 1 part yeast, about 1 part Yucca plant extract, and about 1 part calcium-source material. The antagonistic microorganism may be included in an amount of between about 0.02 parts and about 0.5 parts by weight of the formulation, with about 0.04 parts antagonistic microorganism being preferred in testing to date. The formulation is typically applied to the above ground structures of the plant, including its leaves, flowers, stems, trunk, blossoms and fruit.Type: ApplicationFiled: March 15, 2011Publication date: August 4, 2011Inventor: William Brower
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Publication number: 20110184062Abstract: Compositions and methods to inhibit dry eye as well as other conditions are provided.Type: ApplicationFiled: January 26, 2011Publication date: July 28, 2011Inventor: Irvine L. Dubow
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Publication number: 20110182806Abstract: Systems and methods for enhancing the selective targeting of agents for preferential action at a target with reduced action with healthy tissue distal the target tissue. One or more agents can be combined with nano scale structures/particles for delivery to the target tissue. Appropriate bombardment with accelerated particle radiation, such as proton radiation, induces the release of the agents at the target site. Nano carriers can be combined with therapeutic and/or imaging enhancement agents. Imaging of the target tissue can provide a verification of the delivered dose of particle radiation. Nanocarriers can be provided with an outer shell selected for biocompatibility and durability in the in vivo environment and further selected to provide a feedback mechanism in the treatment environment to accelerate the release of the agent and reduce a total radiation dose needed for that release.Type: ApplicationFiled: January 27, 2010Publication date: July 28, 2011Inventors: Reinhard Schulte, Gilmer Valdes-Diaz
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Publication number: 20110184039Abstract: A pharmaceutical composition comprising: a) a 5-HT1 agonist; b) an NSAID; and c) a disintegrant characterised in that the disintegrant comprises between about 15 to about 50% w/w based on the weight of the composition, said composition optionally comprising one or more other pharmaceutically acceptable excipients.Type: ApplicationFiled: February 4, 2009Publication date: July 28, 2011Inventors: Brett Antony Mooney, Panagiotis Keramidas
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Publication number: 20110177176Abstract: A gel-based comestible and method of preparing same. In one embodiment of the invention, the gel-based comestible is consumed in one bite without the need for a spoon or other utensil, and supplies the consumer with about 200 mg/serving caffeine, 1000 mg/serving taurine, and 100% of the recommended daily allowances of vitamins B3, B5, B6 and B12.Type: ApplicationFiled: January 17, 2011Publication date: July 21, 2011Applicant: PepsiCo, Inc.Inventor: Vidya Sridhar
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Publication number: 20110178044Abstract: Methods, formulations, and drug delivery systems are provided for enhancing the flux of a transdermally administered hydrophilic drug using a basic permeation enhancer composition. The enhancer composition contains an inorganic hydroxide and a weaker, nitrogenous base, wherein the bases are selected such that a 0.1M aqueous solution of the nitrogenous base has a pH that is about 1.0 to about 6.5 lower than the pH of a 0.1M aqueous solution of the inorganic hydroxide. Additionally, the molar ratio of the nitrogenous base to the inorganic hydroxide in the enhancer composition is in the range of about 0.5n:1 to about 20n:1, where n is the number of hydroxide ions per molecule of the inorganic hydroxide.Type: ApplicationFiled: April 4, 2011Publication date: July 21, 2011Inventors: Tsung-Min Hsu, Eric Jacobson, Eric C. Luo, Alan T.J. Hickey, Nicole T. Gricenko
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Publication number: 20110171188Abstract: The invention relates to a non-thermal plasma for treatment of a surface, particularly for the treatment of a wound (1), wherein the plasma comprises a partially ionized carrier gas and at least one additive, which preferably has a sterilizing effect on the treated surface and/or improves the healing of the wound (1). Further, the invention relates to a corresponding apparatus and method.Type: ApplicationFiled: August 17, 2009Publication date: July 14, 2011Applicant: Max-Planck-Gesellschaft zur Foerderung der Wissenschaften e.VInventors: Gregor Morfill, Bernd Steffes, Tetsuji Shimizu, Rene Pompl, Tetiana Nosenko, Wilhelm Stolz, Georg Isbary, Hans-Ulrich Schmidt
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Publication number: 20110165207Abstract: The invention relates to inorganic-organic composite particles, in particular composite nanoparticles, wherein the composite particles comprise at least one organically based material containing or being made of at least one wax and an inorganically based material, and to a method for the production thereof and to the use thereofType: ApplicationFiled: March 26, 2009Publication date: July 7, 2011Inventor: Ulrich Nolte
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Publication number: 20110165208Abstract: Disclosed herein are a color capsule composition, which contains a polymer and a plasticizer swelling the polymer so as to allow the capsule particles to easily break and in which the capsule particles have a porous structure that boosts the effects thereof, and a method for preparing the color capsule composition. The preparation method comprises: uniformly mixing a color pigment, a plasticizer and a polymer in a first solvent to produce a first mixture solution; spray-drying the first mixture solution to produce core particles in which the color pigment is covered by the polymer; uniformly mixing the obtained core particles, a functional pigment and a second solvent to produce a second mixture solution; and spray-drying the second mixture solution to produce in which a coating layer of the functional pigment is formed on the outer surface of the polymer.Type: ApplicationFiled: May 28, 2010Publication date: July 7, 2011Inventors: Chul-Hwan Kim, Tae-Sung Ko, Han-Joon Kim, Choa-Jin Kim, Jong-Hyun Choi, Chang-Hun Ji
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Patent number: 7973085Abstract: A gel composition having the formula R1O-[(AO)k(EO)m(AO)n]-R2 comprises (a) 0.1 to 60 mass % of a block-type alkylene oxide derivative, (b) an oil, and (c) 0.1 to 10 mass % of water. AO represents a C3-C4 oxyalkylene group; EO represents an oxyethylene group; k and n represent average addition mole numbers of the oxyalkylene group and m represents average addition mole number of the oxyethylene group, 1?m?70 and 1?k+n?70. The oxyethylene group is 20 to 80 mass % with respect to the sum of the oxyalkylene group (AO) and the oxyethylene group. R1 and R2 may be identical to or different from one another and are each a C1-C4 hydrocarbon group or a hydrogen atom. The composition has a continuous phase comprising the oil; and the viscosity of the composition at 25° C. is 500 mPa·s or more.Type: GrantFiled: June 6, 2007Date of Patent: July 5, 2011Assignee: Shiseido Company Ltd.Inventors: Akira Ishikubo, Takashi Ohmori, Yuki Suzuki
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Publication number: 20110150797Abstract: The present invention relates to a composition for treating keratin fibres, and in particular human keratin fibres such as the hair, comprising, in a cosmetically acceptable medium, one or more alkanolamines, one or more basic amino acids and one or more additional alkaline agents chosen from aqueous ammonia; ammonium salts of acids whose pKa at 25° C. is greater than 4; alkali metal or alkaline-earth metal hydroxides, carbonates, carbamates and hydrogen carbonates. The present invention also relates to processes for bleaching and/or dyeing keratin fibres, and also to multi-compartment devices or ‘kits’ for performing these processes.Type: ApplicationFiled: December 17, 2008Publication date: June 23, 2011Inventors: Frédéric Legrand, Jean-Marc Ascione
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Publication number: 20110152195Abstract: The present invention relates to a bone cement precursor system that is presented in the form of two shelf-stable pastes which have been terminally sterilized and are held in separate containers during product transport and storage. When the product is used during surgery, these pastes inject to a site of application through a static mixing device by the action of applied injection force. When the two pastes are mixed, they start to react to each other while injecting out. The resulting composition is highly biocompatible, osteoconductive, injectable, rapid setting and bioresorbable, and is useful in connection with bone repair procedures, for example, in the craniomaxillofacial, trauma and orthopedic areas.Type: ApplicationFiled: December 16, 2010Publication date: June 23, 2011Applicant: Howmedica Osteonics Corp.Inventors: Donal O'Mahony, Venkat R. Garigapati, Adrian Sun Wai, Brian Hess, Matthew E. Murphy
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Publication number: 20110151014Abstract: Coprocessed compositions containing microcrystalline cellulose and calcium carbonate, wherein the weight ratio of microcrystalline cellulose to calcium carbonate is relatively high, are useful as excipients in the preparation of solid dosage forms containing active pharmaceutical ingredients, particularly those prepared by processes involving multiple compaction steps. Such compositions may be obtained, for example, by preparing aqueous slurries or wet masses of microcrystalline cellulose and calcium carbonate and drying such slurries or wet masses to produce particulate products. The coprocessed products exhibit improved recompactibility, as compared to coprocessed products having lower microcrystalline cellulose:calcium carbonate weight ratios or as compared to physical dry blends of the two excipients.Type: ApplicationFiled: December 8, 2010Publication date: June 23, 2011Applicant: FMC CORPORATIONInventors: Gregory Thoorens, Bruno LeClercq, Thomas Ruszkay
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Publication number: 20110150938Abstract: The present invention concerns size- and shape-controlled, colloidal superparticles (SPs) and methods for synthesizing the same. Ligand-functionalized nanoparticles such as nonpolar-solvent-dispersible nanoparticles, are used, and the solvophobic interactions can be controlled. Advantageously, supercrystalline SPs having a superlattice structure, such as a face-centered cubic structure, can be produced. Further, the methods of the invention can provide SPs that self-assemble and are monodisperse. The SPs can be doped with organic dyes and further assembled into more complex structures.Type: ApplicationFiled: August 15, 2008Publication date: June 23, 2011Applicant: University of Florida Research Foundation, Inc.Inventors: Y. Charles Cao, Jiaqi Zhuang, Huimeng Wu, Yongan Yang
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Publication number: 20110150765Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.Type: ApplicationFiled: September 15, 2009Publication date: June 23, 2011Inventors: Edward S. Boyden, Daniel B. Cook, Roderick A. Hyde, Eric C. Leuthardt, Nathan P. Myhrvold, Elizabeth A. Sweeney, Lowell L. Wood, JR.
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Publication number: 20110136912Abstract: The present invention is directed to an ophthalmic emulsion. The emulsion has a unique combination of ingredients that promotes the stability of small oil droplets within the emulsion. The emulsion also includes a mucoadhesive polymer that aid in delivering a lipid to the ocular surface.Type: ApplicationFiled: December 2, 2010Publication date: June 9, 2011Inventors: Howard Allen Ketelson, David L. Meadows
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Publication number: 20110129506Abstract: The present invention relates to the use of titanium dioxide pigments and/or iron oxide pigments based on platy substrates for colouring food products and pharmaceutical products.Type: ApplicationFiled: November 22, 2010Publication date: June 2, 2011Inventors: Ralf SCHWEINFURTH, Uta Hillgärtner
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Publication number: 20110130291Abstract: A process for treating foliage by retaining an active agent in contact with the foliage is provided that includes the application of a biologically active ingredient carrier granule. The granule includes a mineral component, a cellulosic component, and a binder flowing upon wetting intermixed with the mineral component and the cellulosic components. A biologically active ingredient is added to the granule to treat the foliage. The foliage in either a dry or pre-wetted state. The contact of the granule with water causes the granule to flow to form a coherent film bound by the binder on the foliage with the active agent retained in the film in contact with the foliage.Type: ApplicationFiled: November 30, 2010Publication date: June 2, 2011Applicant: The Andersons, Inc.Inventors: Timothy D. Birthisel, Joe Schumski, IV
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Patent number: 7951404Abstract: A storage-stable aqueous concentrate for the preparation of a disinfectant and a disinfectant obtainable from such a concentrate by dilution are disclosed. The concentrate comprises hydrogen peroxide, colloidal silver, a biopolymeric stabilizer such as gum arabic, and phosphoric acid. In order to improve long-term stability and to reduce initial decomposition of the hydrogen peroxide in the first few days after preparing the concentrate, the concentrate further comprises sodium nitrate or sodium sulfate. The concentrate is free of any synthetic organic complexing agents, thus rendering the concentrate suitable for food- and drinking water applications. Also disclosed are methods of preparing and using the concentrate.Type: GrantFiled: September 5, 2008Date of Patent: May 31, 2011Assignee: Sanosil AGInventor: Janos Gömöri
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Patent number: 7943644Abstract: Specific azole compounds are outstandingly suitable for stabilizing iodine-containing biocides in industrial materials, more particularly in paints based on alkyd resin.Type: GrantFiled: February 21, 2007Date of Patent: May 17, 2011Assignee: LANXESS Deutschland GmbHInventors: Hermann Uhr, Johannes Kaulen, Thomas Jaetsch, Peter Spetmann
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Publication number: 20110111061Abstract: Compositions and methods for the treatment of fracture and metastatic bone cancer are disclosed.Type: ApplicationFiled: November 19, 2010Publication date: May 12, 2011Inventors: John A. Handal, Solomon P. Samuel
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Publication number: 20110104077Abstract: The present invention proposes a magnetic nanocomposite with multi-biofunctional groups, which comprises a core and a shell wrapping the core, wherein the core contains magnetic nanoparticles, and wherein the shell is made of a conductive polymer with multi-biofunctional groups where a medicine, an antibody or a fluorescent label can be attached.Type: ApplicationFiled: May 4, 2010Publication date: May 5, 2011Inventors: Mu-Yi Hua, Hung-Wei Yang, Rung-Ywan Tsai, Kuo-Chen Wei, Pin-Yuan Chen, Hao-Li Liu
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Publication number: 20110105620Abstract: A solid pharmaceutical composition suitable for oral administration, comprising: (a) S 1 P receptor agonist; and (b) a sugar alcohol.Type: ApplicationFiled: January 10, 2011Publication date: May 5, 2011Inventors: Tomoyuki Oomura, Madhusudhan Pudipeddi, Colleen Ruegger, Alan Edward Royce, Masaki Sasaki, Tokuhiro Tamura
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Publication number: 20110091577Abstract: The invention provides implantable drug releasing materials comprising a calcium phosphate composition, a biodegradable polymer adsorbed onto the calcium phosphate composition, wherein the polymer comprises acidic amino acid residues, and a drug adsorbed onto or reacted with the polymer. The invention is further directed to dental and bone implants and implantable medical devices comprising the implantable drug releasing material, methods for preparing the implantable drug releasing material, and methods for delivering the implantable drug releasing material to bone or teeth.Type: ApplicationFiled: April 15, 2009Publication date: April 21, 2011Inventor: Lance D. Silverman
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Publication number: 20110091546Abstract: The present invention provides rapid disintegrating tablets in oral cavity having a shortened disintegration time in oral cavity as well as a sufficient hardness with compared to rapid disintegrating tablets of the prior art. The above objective is solved by a composition for rapid disintegrating tablets in oral cavity, wherein components (a) to (c) are contained in such manner that (a) saccharides consisting of a combination of mannitol and xylitol is 40 to 90 parts by weight; (b) the inorganic excipient is 1 to 30 parts by weight; and (c) the disintegrating agent is 5 to 40 parts by weight, provided that the total amount of (a), (b) and (c) is 100 parts by weight.Type: ApplicationFiled: October 20, 2010Publication date: April 21, 2011Applicant: FUJI CHEMICAL INDUSTRY CO., LTD.Inventors: Nobukazu TANAKA, Yoshiro Nagai, Hiroshi Kawaguchi, Tadashi Fukami, Terumasa Hosokawa
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Publication number: 20110081555Abstract: A stable, aqueous suspension concentrate which includes a solid polymeric dispersant comprising one or more anionic polymeric dispersing agents, optionally a co-dispersant which preferably is a homopolymer and/or a copolymer of a heterocyclic vinyl lactam, preferably in a wt. ratio of 0.1:1 to 1:0.1, a UV-labile, water-insoluble biocide active, and a UV-blocker or UV-absorber to stabilize said active upon storage and/or exposure to sunlight or UV radiation.Type: ApplicationFiled: December 13, 2010Publication date: April 7, 2011Applicant: ISP INVESTMENTS INC.Inventors: Xianbin Liu, Karen Winkowski, Kolazi S. Narayanan, Jean-Jacques Gulka
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Publication number: 20110082071Abstract: The invention relates to a delivery system for an active ingredient. The system provides an encapsulating material for the active ingredient, wherein the encapsulating material is formed by combining a cationic component, an anionic component and the active ingredient. The anionic component is a mixture of carbonate and phosphate moieties, wherein the molar ratio of carbonate to phosphate moieties is from 9:1 to 1:9.Type: ApplicationFiled: May 14, 2009Publication date: April 7, 2011Inventors: Amal Elabbadi, Olivier Haefliger, Lahoussine Ouali
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Patent number: 7910090Abstract: The present invention provides a base composition that allows for the formulation of non-irritating cosmetic and/or dermatological compositions. The base composition includes one or more of electrolyte, buffer, mild preservative, lubricant, or any combinations thereof. It is preferred that one or more of the above components are eye-safe and/or eye-compatible. The present invention also provides photoprotective cosmetic and/or dermatological compositions that include the base composition and one or more sunscreen active components and are non-irritating to mammalian eyes.Type: GrantFiled: January 18, 2006Date of Patent: March 22, 2011Assignee: Playtex Products, Inc.Inventors: Olga V. Dueva-Koganov, James P. SaNogueira
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Publication number: 20110046606Abstract: Catheter injectable depot compositions are provided that include a bioerodible, biocompatible polymer, a solvent having miscibility in water of less than or equal to 7 wt. % at 25° C., in an amount effective to plasticize the polymer and form a gel therewith, a thixotropic agent, and a beneficial agent. The solvent comprises an aromatic alcohol, an ester of an aromatic acid, an aromatic ketone, or mixtures thereof. The compositions are have substantially improved the shear thinning behavior and reduced injection force, rendering the compositions readily implanted beneath a patient's body surface by injection.Type: ApplicationFiled: October 18, 2010Publication date: February 24, 2011Inventors: Guohua Chen, Paul R. Houston, Lothar Kleiner, John J. Spaltro
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Publication number: 20110046686Abstract: Described herein are methods and compositions comprising a mixture of silk polymer and hydroxyapatite. The methods described herein can be used to prepare a mixture of silk polymer and hydroxyapatite and further provide mixtures that can be molded into a desired shape. Also encompassed herein are compositions comprising a mixture of silk polymer and hydroxyapatite having a desired shape, which can further be implanted, for example, to facilitate bone healing or tooth structure or support. Such compositions can also include agents, such as therapeutic agents, or cells.Type: ApplicationFiled: February 6, 2009Publication date: February 24, 2011Applicant: TRUSTEES OF TUFTS COLLEGEInventors: David L. Kaplan, Hyeon Joo Kim, Gerard Kugel
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Patent number: 7892576Abstract: Tablet comprising at least one biologically active substance and an excipient, in which the excipient contains calcium carbonate and at least one additive selected from fatty acids, their salts, their esters, lipid materials, polysaccharides, polyvinylpyrrolidone and polyvinylpyrrolidone derivatives, acrylic compounds, mono-, di- or triglyceride esters, animal proteins, and mixtures of at least two of these. Method for producing these tablets. Use of calcium carbonate in tablets containing at least one biologically active substance, for the prolonged release of this substance.Type: GrantFiled: February 13, 2006Date of Patent: February 22, 2011Assignee: Solvay (Societe Anonyme)Inventors: Karine Cavalier, Didier Sy, Roberto Rosa, Bernard Bataille, Michele Delalonde, Gilles Baylac, Alberto Galasco
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Publication number: 20110034391Abstract: The shaped article is obtained via a cementitious reaction of a particulate composition reactive with water, whereby said reaction is obtained between said composition and an aqueous, liquid or gaseous phase. The particles of the shaped article are present in the form of interlocked particles, whereby the interlocking of said particles is obtained in a 100% water-saturated atmosphere.Type: ApplicationFiled: October 18, 2010Publication date: February 10, 2011Applicants: DR. H.C. ROBERT MATHYS STIFTUNG, SYNTHES GMBHInventors: Marc Bohner, Anna Malsy
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Publication number: 20110028568Abstract: The invention relates to a preparation for a magnesium ammonium phosphate cement. There is provided a preparation comprising (a) a magnesium calcium phosphate of the formula MgxCay(PO4)2Oz, wherein x+y?4, x>1, y>0, z=x+y?3 and z?0; (b) an ammonium salt; and (c) water; wherein the ammonium salt and the water can be present partially or completely as an aqueous solution of the ammonium salt.Type: ApplicationFiled: February 18, 2009Publication date: February 3, 2011Applicant: INNOTERE GMBHInventor: Uwe Gbureck
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Patent number: 7879346Abstract: The present invention provides a cosmetic composition including oil phase ingredients 40-90% by weight and powder ingredients 10-60% by weight. The oil phase ingredients include volatile oil 5-70 parts by weight and dimethicone/vinyl-dimethicone crosspolymer 0.1-5 parts by weight. The powder ingredients include organic hectorite 0.5-40 parts by weight, methyl methacrylate crosspolymer 0.5-5 parts by weight, and pulverulent body 0.5-50 parts by weight.Type: GrantFiled: August 9, 2006Date of Patent: February 1, 2011Assignee: STC Nara Co., Ltd.Inventors: Kye-Ho Lee, Jong-Hwan Kim, Sung-Ho Chung
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Publication number: 20110021899Abstract: An electrically conductive coating composition that includes a polymeric mixture, an electrically conductive material dispersed within the polymeric mixture and, optionally, one or more bioactive agents is described.Type: ApplicationFiled: July 7, 2010Publication date: January 27, 2011Applicant: SurModics, Inc.Inventors: James H. Arps, Peter J. Barnett, Jeffrey J. Missling
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Patent number: 7858656Abstract: A controlled release melatonin tablet having a slow release nucleus of melatonin, hydroxypropyl methylcellulose, a lubricant, a volume excipient and a glidant, wherein 95% of the melatonin is released within 5 hours in an oscillating tray containing gastric/intestinal juice at 37° C. and a fast release cortex coating on said nucleus of melatonin, hydroxypropyl methylcellulose and a volume excipient, wherein at least 95% of the melatonin is released within 10 minutes in an oscillating tray containing gastric/intestinal juice at 37° C.Type: GrantFiled: November 13, 2007Date of Patent: December 28, 2010Assignee: Ambros Pharma S.R.L.Inventor: Bojidar M. Stankov
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Patent number: 7858123Abstract: The invention provides compositions, methods and devices relating to a silaceous oxide that generates a reduced heat of hydration upon contact with blood. By reducing the heat of hydration, the compositions provide a hemostatic agent that attenuates a tissue burning side effect of conventional hemostatic agents without adversely affecting the wound healing properties of the composition.Type: GrantFiled: April 4, 2006Date of Patent: December 28, 2010Assignee: The Regents of the University of CaliforniaInventors: Galen D. Stucky, Todd A. Ostomel, Qihui Shi, Peter K. Stoimenov, Patricia A. Holden
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Publication number: 20100322981Abstract: The present invention relates to (interference) pigments comprising a plate-like substrate, a layer of SnO2, and/or a layer of a metaloxide, which is selected from Fe2O3, TiO2, ZrO2 and/or HfO2, said layer(s) being doped with Mo and/or W, or pigments comprising a plate-like substrate, a layer of a metal oxide, which is selected from Fe2O3, TiO2, ZrO2 and/or HfO2, said layer(s) being doped with Nb and/or Ta, a method of producing the (interference) pigments and their use in paints, ink-jet printing, for dyeing textiles, for pigmenting coatings, printing inks, plastics, cosmetics, glazes for ceramics and glass. The pigments of the present invention have very bright color and show color flop.Type: ApplicationFiled: November 7, 2008Publication date: December 23, 2010Applicant: BASF SEInventors: Patrice Bujard, Marc Baysang, Philippe Bugnon
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Patent number: 7846416Abstract: Anitrate-nitrogen-reducing agent for a farm product, comprising as an active ingredient a hydroxide solid solution represented by the formula (1), [(M12+)1-x(M22+)x]1-z(M3+)z(OH)2(An?)z/n·mH2O??(1) wherein M12+ represents Ca and/or Mg, M22+ represents at least one essential mineral selected from Fe, Mn, Zn, Cu, Ni and Co, M3+ represents at least one trivalent metal, An? represents an anion having a valence of n, x is a positive number in the range of 0<x<0.5, m is 0 or a positive number in the range of 0?m<10, z is a positive number in the range of 0<z<0.4, and n is a positive number in the range of 1?n?10, and/or the formula (2), (M12+)1-x(M22+)x(OH)2??(2) wherein M12+, x and M22+ are as defined in the formula (1).Type: GrantFiled: November 2, 2005Date of Patent: December 7, 2010Assignee: Kabushiki Kaisha Kaisui Kagaku KenkyujoInventor: Shigeo Miyata
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Publication number: 20100278759Abstract: The present invention relates to an oil-in-water emulsion topical delivery system comprising an oil phase; an aqueous phase; phenoxyethanol; an effective exfoliatingamount of a hydrophobic hydroxycarboxylic acid; a non-ionic emulsifier having an HLB of from about 7 to about 10; and at least one skin-supporting ordermatopharmaceutically active agent.Type: ApplicationFiled: February 8, 2007Publication date: November 4, 2010Inventor: Howard Murad
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Publication number: 20100273896Abstract: A method of producing products includes diluting a mater in a quality water as a dilution water a plurality of times until solid stable water clusters are formed having a plurality of water molecules connected with one another by electrical dipole interaction via internal electric field of ions and having a permanent electric dipole moment with an electrical field surrounding the solid stable water clusters, and the produced solid stable water clusters can be used with an additional material to produce the final product.Type: ApplicationFiled: December 3, 2009Publication date: October 28, 2010Inventors: Shui Yin Lo, David Gann, Geng Xu