Abstract: Compositions and methods of their use to adhere a variety of materials together are disclosed herein. The compositions include at least tetra calcium phosphate, an effective amount of a compound that is structurally similar to phosphoserine, and can be mixed with an aqueous solution. The compositions provide adhesive and cohesive strength in both wet and dry environments and exhibit significant bond strength upon curing.

Abstract: The invention provides an infiltrant for dental application that comprises crosslinking monomers, having a penetration coefficient PC>50 cm/s. In accordance with the invention the infiltrant comprises at least one nanoscale radiopaque filler and/or radiopaque organic compound, while ensuring sufficient contrast to surrounding tooth and bone tissue in X-ray diagnostics.

Abstract: The present invention provides dental fillers having the optical and/or mechanical characteristics required to dental materials, a method of producing the same, and a dental composite material prepared with use of the dental filler. More specifically, the present invention provides a dental filler containing a zirconium silicate compound, especially a zirconium trisilicate compound with a wadeite type crystalline structure and having an average particle diameter in the range from 2 to 50,000 nm, a method of producing the same, a dental composite material containing the dental filler and a hardenable resin selected from an acrylic resin, a methacrylic resin, an epoxy resin, a vinyl resin, a urethane resin and the like.

Abstract: Zirconium-containing BaO- and PbO-free X-ray opaque glasses having a refractive index nd of about 1.480 to about 1.517 and a high X-ray opacity with an aluminum equivalent thickness of at least about 180% are provided. Such glasses are based on a SiO2—B2O3—Cs2O—K2O—La2O3 system with additions of Al2O3, Li2O, Na2O and/or ZrO2. Such glasses may be used, in particular, as dental glasses or as optical glasses.

Abstract: A bone cement comprising an acrylic polymeric component and an inorganic component comprising a bioactive glass or glass-ceramic, comprising at least one metal oxide having an anti-bacterial activity, wherein said glass or glass-ceramic component is adapted to release ions of said metal in contact with physiological fluids. The bone cement performs a sustained antibacterial action, also promoting binding with the tissues with which it is contacted, and it is advantageously employed in the fixation of orthopaedic prostheses, in the production of temporary prostheses and in spinal surgery.

Abstract: A fluid cement for medical use for bone reconstruction, in particular for filling the vertebral body, and a binary composition which is intended for the preparation of such a cement. A device for conditioning the binary composition, and a method of preparing a bone cement from a binary composition. The fluid cement according to the invention comprises: a) approximately 70% to 85% by weight of a polymer comprising a polymethylmethacrylate and a methylmethacrylate monomer, and b) approximately from 15 to 30% by weight of a radio-opaque composition. Preferably, the radio-opaque composition comprises a radio-opacifier, such as a barium sulphate and zirconium dioxide, in a mixture with a calcium phosphate, for example hydroxyapatite.

Abstract: Zirconium-containing BaO- and PbO-free X-ray opaque glasses having a refractive index nd of about 1.54 to about 1.58 and a high X-ray opacity with an aluminum equivalent thickness of at least about 500% are provided. Such glasses are based on a SiO2—B2O3—Al2O3—R2O—RO—La2O3—ZrO2 system with optional additions of SnO2. Such glasses may be used, in particular, as dental glasses or as optical glasses.

Abstract: A dental restorative composition comprises: (A) polymerizable monomer(s) selected from hydroxyethyl (meth)acrylate phosphate, hydroxypropyl (meth)acrylate phosphate, hydroxybutyl (meth)acrylate phosphate, dipentaerythritol penta(meth)acrylate phosphate, pentaerythritol tri(meth)acrylate phosphate, phenyl (meth)acryloxyethyl phosphate, and a combination thereof; (B) polymerizable monomer(s) having a molecular weight of 100-250, at least one hydroxyl group, and at least one ethylenically unsaturated group; (C) polymerizable monomer(s) having a molecular weight of 270-900, at least two ethylenically unsaturated groups and no acidic functional group; (D) photo-initiator(s); and (E) filler(s) each having a mean particle size of more than 0.005 microns and less than 70 microns. The weight ratio of (A+B):(C) ranges from 30:70 to 90:10, and the composition has a shear bond strength of at least 10MPa to both dentin and enamel after being light-cured.

Abstract: The present invention relates to shape-memory polymers which are distinguished by the fact that they comprise BiOCl pigments as X-ray contrast agents. Polymers doped in this way are used, in particular, in medical technology products, such as, for example, stiffening pins for the spinal column, tooth root cones, as bone cement and in catheter materials.

Abstract: The invention provides a fluid cement for medical use for bone reconstruction, in particular for filling the vertebral body, and a binary composition which is intended for the preparation of such a cement. The invention also provides a device for conditioning the binary composition, and a method of preparing a bone cement from a binary composition. The fluid cement according to the invention comprises: a) approximately 60% to 85% by weight of a polymer comprising a polymethylmethacrylate and a methylmethacrylate monomer and b) approximately from 15 to 40% by weight of a radio-opaque composition. Preferably, the radio-opaque composition comprises a radio-opacifier, such as barium sulfate and zirconium dioxide, in a mixture with a calcium phosphate, for example apatite hydroxide.

Abstract: There are provided a novel polymerizable composition having an X-ray contrast property and excellent transparency, a cured product thereof, and a composite material comprising powder of the cured product. More specifically, there are provided a polymerizable composition comprising (A) an inorganic oxide having an X-ray contrast property and an average particle diameter of 100 nm or smaller, (B) a surface modifier, (C) a polymerizable compound and (D) a polymerization initiator, a cured product obtained by polymerizing these components, and a composite material comprising powder of the cured product.

Abstract: A dental filling material comprising a polybutylene polymer having a molecular weight of about 10,000 to about 100,000 and being viscoelastic at about 20° C. The composition may include other polymeric resins, fillers, plasticizers and other additives typically used in dental materials. The filling material is used for the filing of root canals.

Abstract: The invention concerns a dental filling material with dual hardening mechanism, wherein i) a first hardening mechanism is based on a photocuring reaction, preferably a radical reaction, and ii) a second hardening mechanism is dependent on H2O as a reactant, especially as a ligand. Preferably, the second hardening mechanism is a gypsum-type reaction. Owing to the expansion of the composition an excellent marginal seal can be achieved, while the first hardening mechanism allows for a rapid cure on demand.

Abstract: The present invention provides a composition based on calcium aluminate cement (CAC) for application in endodontics, comprising: (a) a cement—Al2O3 (>68.5 wt %), CaO (<31 wt %), SiO2 (0.3-0.8 wt %), MgO (0.4-0.5 wt %), and Fe2O3 (<0.3 wt %); (b) additives: dispersant at a content of 0.4 to 0.8% by weight of the cement, a plasticizer at a content of 2.0 to 4.0% by weight of the cement, and a radiopaque agent at a content of 20 to 35% by weight of the cement; and (c) water, wherein water/cement ratio lies in the range of 0.19-0.24 in the presence of additives. Cementitious product obtained thereof, after setting time, is also disclosed and characterized by enhanced properties when compared to the most used commercial repair cement, MTA.

Abstract: A dental filler and dental resin restorative composition containing the dental filler is provided. The dental filler is prepared by pre-treating an acid-reactive filler with a polymerizable monomer or oligomer pre-treatment chemical having at least one acid or acid-precursor functional group, at least one polymerizable unsaturated carbon-carbon bond, and a molecular weight of about 1,000 grams per mole or less.

Abstract: A dental root canal sealing composition curable in the absence of a polymerisation initiator, which comprises (i) an amino terminated prepolymer having a viscosity at 23° C. of less than 100 Pas. (ii) a compound capable of undergoing polyaddition with the aminoterminated prepolymer (i); (iii) 40 to 85 wt.-% of a filler for providing a minimum radioopacity of at least 3 mm/mm Al.

Abstract: A carrier composition for filling a tooth root canal, comprising a cross-linkable material.

Abstract: Featured are a biocompatible, injectable, self-setting, cohesive, bone-bonding and remodeling calcium phosphate composite material and its use in methods of repairing defective bone, e.g., in vertebroplasty augmentation and kyphoplasty.

Abstract: Zirconium-containing BaO- and PbO-free X-ray opaque glasses having a refractive index nd of about 1.54 to about 1.58 and a high X-ray opacity with an aluminum equivalent thickness of at least about 500% are provided. Such glasses are based on a SiO2—B2O3—Al2O3—R2O—RO—La2O3—ZrO2 system with optional additions of SnO2. Such glasses may be used, in particular, as dental glasses or as optical glasses.

Abstract: Composite material with a polymerisable organic binder, characterised in that it contains a filler with filler particles which have the shape of a torus.

Abstract: A paste is provided from which bone cement can be formed, which is to the largest extent possible bubble-free and has a high impact strength. The paste includes (i) 15-50 weight percent of at least one mono-functional, hydrophobic methacrylic acid ester, (ii) 40-85 weight percent of at least one filler, (iii) 0.01-4 weight percent of at least one radical initiator soluble in the methacrylic acid ester (i) and having at least one peroxide group, (iv) 0.01-4 weight percent of at least one radical initiator soluble in the methacrylic acid ester (i) and having no peroxide groups, (v) 0.000001-3 weight percent of at least one accelerator soluble in the methacrylic acid ester (i) and capable of forming radicals from the radical initiators according to (iii) and (iv), (vi) 0.001-5 weight percent of at least one halide salt, and (vii) 0.2-3 weight percent of at least one cross-linking agent.

Abstract: An methacrylate bone cement is toughened and rendered radiopaque by reinforcing with electrospun microfibers including a radiopacifier and antimicrobial agents to provide a bone cement for use in repairing bone or other hard tissues.

Abstract: The disclosure is directed to a composition includes a first component and a second component. The first component includes a poly(methyl methacrylate) (PMMA), a contrast agent, and a radical donor. The second component includes methyl methacrylate (MMA), a radical scavenger, and a polymerization accelerator. The composition has an average setting time of about 13 minutes. The disclosure is further directed to a kit and a method of making the above-mentioned composition.

Abstract: A one-component self-etching self-priming dental adhesive composition is disclosed. The composition comprises glycerol phosphate di(meth)acrylate monomer, at least one mono-functional polymerizable monomer having just one ethylenically unsaturated group, at least one multi-functional polymerizable monomer having at least two ethylenically unsaturated groups, at least one aprotic solvent, at least one protic solvent, and at least one polymerization initiator.

Abstract: A curable composition for dental use, containing a polymerizable monomer, inorganic particles (A) having irregular shapes and an average particle size of from 1.0 to 5.0 ?m, wherein the inorganic particles (A) are surface-treated with a silane coupling agent (a) represented by the formula (I): wherein R1 is a hydrogen atom or a methyl group, R2 is a hydrolyzable group, R3 is a hydrocarbon group having 1 to 6 carbon atoms, X is an oxygen or sulfur atom, p is 2 or 3, and q is an integer of from 8 to 13, and inorganic particles (B) having irregular shapes and/or spherical or nearly spherical shapes, and an average particle size of from 0.01 to 0.

Abstract: A dental restorative composition comprising: (A) polymerizable monomer(s) having at least one phosphorus-containing acidic moiety and at least one ethylenically unsaturated group; (B) polymerizable monomer(s) having a molecular weight of 100-250, at least one hydroxyl group, and at least one ethylenically unsaturated group; (C) polymerizable monomer(s) having a molecular weight of 270-900, at least two ethylenically unsaturated groups and no acidic functional group; (D) photo-initiator(s); and (E) filler(s) each having a mean particle size of more than 0.005 microns and less than 70 microns. The weight ratio of (A+B):(C) ranges from 30:70 to 90:10, the concentration of (A) is 10-50 wt. %, the concentration of (B) is 15-60 wt. %, and the composition has a shear bond strength of at least 10 MPa to both dentin and enamel. Also provided is a method for filling a dental cavity with the composition without first treating the dental cavity with an etchant, a primer and/or an adhesive.

Abstract: Filler based on glass particles which contain a homo- or copolymer of vinyl chloride on the surface, process for its preparation and its use as a dental material.

Abstract: The invention describes polymerisable compositions which contain higher molecular weight di(meth)acrylates, curing agents and X-ray-opacifying additives, which result in fully cured, readily removable materials and which are especially suitable for filling and sealing root canals.

Abstract: Compositions comprising a hyperbranched compound and a polymer prepared from reactants comprising at least one (meth)acrylate monomer, and dental filling compositions comprising a hyperbranched compound.

Abstract: Compositions comprising an acidic polymer compound and a (meth)acrylic copolymer prepared from reactants comprising at least one aliphatic, aromatic, or aralkyl (meth)acrylate monomer and at least one ethylenically unsaturated monomer having a polar group or a siloxane group, and dental filling compositions comprising the composition, and methods of using the compositions

Abstract: Improved compositions comprising a mixture of gutta-percha and a hydraulic material containing calcium silicate, calcium aluminate, calcium phosphate, and calcium sulfate compounds are provided. Preferably, the composition includes hydroxylapatite mineral. The composition is particularly suitable for obturating and sealing dental root canals. The composition should provide a stable barrier to bacterial and fluid leakage in the root canal system of a tooth. In addition, the composition should help promote the growth of new bone and tissue surrounding the root tip area.

Abstract: The present invention relates to a dental glass containing 50 to 70 wt. % of SiO2, 5 to 18 wt. % of Al2O3, 6.1 to 30 wt. % of MgO, 1 to 15 wt. % of La2O3, 1 to 15 wt. % of WO3, 0.1 to 8 wt. % of ZrO2, and optionally further oxides except for the oxides of Sr, Ba or alkali metals, wherein the stated quantities in total add up to 100 wt. %.

Abstract: The present invention relates to an injectable bone cement for filling bones with mechanical properties equivalent to those of vertebral spongy bone comprising 70 to 99 wt. % of an acrylic polymer combined with an inorganic type radiopaque compound and 1 to 30 wt. % of calibrated hydrophilic flexible solid particles, said calibrated hydrophilic flexible solid particles being chosen from gelatin, poly(glycerol sebacate) or a mixture thereof. A bone cement according to the invention is particularly intended for vertebroplasty, kyphoplasty or cementoplasty.

Abstract: Zirconium-containing BaO- and PbO-free X-ray opaque glasses having a refractive index nd of about 1.518 to about 1.533 and a high X-ray opacity with an aluminum equivalent thickness of at least about 180% are provided. Such glasses are based on a SiO2—Al2O3—B2O3 system with additions of K2O, ZrO2, and one or both of La2O3 and Cs2O. Such glasses may be used, in particular, as dental glasses or as optical glasses.

Abstract: Zirconium-containing BaO— and PbO-free X-ray opaque glasses having a refractive index nd of about 1.480 to about 1.517 and a high X-ray opacity with an aluminum equivalent thickness of at least about 180% are provided. Such glasses are based on a SiO2—B2O3—Cs2O—K2O—La2O3 system with additions of Al2O3, Li2O, Na2O and/or ZrO2. Such glasses may be used, in particular, as dental glasses or as optical glasses.

Abstract: Zirconium-containing BaO- and PbO-free X-ray opaque glasses having a refractive index nd of about 1.57 to about 1.61 and a high X-ray opacity with an aluminum equivalent thickness of at least about 400% are provided. Such glasses are based on a SiO2—Al2O3 —La2O3 —ZrO2 —Cs2O system with additions of Li2O, Na2O, ZnO and/or Ta2O5. Such glasses may be used, in particular, as dental glasses or as optical glasses.

Abstract: A bone substitute composition includes glass flake and a hardenable material. The glass flake is a particle with an aspect ratio of, at least, 20:1. The preferred thickness of the glass flake is in the range from 200 to 1,000 nm and the average particle size is, preferably, from 20 to 60 ?m.

Abstract: A one-component self-etching self-priming dental adhesive composition is disclosed. The composition comprises glycerol phosphate di(meth)acrylate monomer, at least one mono-functional polymerizable monomer having just one ethylenically unsaturated group, at least one multi-functional polymerizable monomer having at least two ethylenically unsaturated groups, at least one aprotic solvent, at least one protic solvent, and at least one polymerization initiator.

Abstract: The invention relates to methods, compositions, kits and systems for determining one or more cement material properties. In one variation, a color change agent is introduced into bone cement to allow a physician to determine when a cement has the desired viscosity for insertion into a patient. In another variation, the composition comprises one or more curable bioactive agents and one or more color change agents. The curable bioactive agent(s) may be one or more bone cement(s). These Bone cements contain a color change agent that allows a physician to tell when the cement has reached the property viscosity for insertion of the bone cement into a patient at the bone site.

Abstract: The invention relates to a polymethylmethacrylate bone cement composition that contains polymethylmethacrylate, radio-opaquer, methylmethacrylate and/or alkylmethacrylates, and an initiator system and comprises, in addition, ferromagnetic and/or superparamagnetic particles of a particle size of up to maximally 500 ?m—which allows it to be heated by alternating magnetic fields—and further contains at least one biodegradable or biocompatible crystalline substance having a melting point in the range of 43-46° C. The cured cement can be used for local over-heating (hyperthermia) therapy in the absence of undesired temperature peaks.

Abstract: An methacrylate bone cement is toughened and rendered radiopaque by reinforcing with electrospun microfibers including a radiopacifier and antimicrobial agents to provide a bone cement for use in repairing bone or other hard tissues.

Abstract: Polymerizable dental material which contains at least one radically-polymerizable monomer and at least one bisacylphosphine oxide of the Formula I, in which R1 is a linear or branched C2 to C14 alkyl residue, which can be interrupted by one or more O atoms, PG-Y—R2—X— or a substituted or unsubstituted, aromatic C6 to C14 radical; R2 is absent or a linear or branched C1 to C20 alkylene radical, which can be interrupted by one or more O atoms; R3 is H, a linear or branched C1 to C6 alkyl residue or PG-Y—R2—X—; R4 is a linear or branched C1-C6 alkyl or —O—C1-C6 alkyl residue; R5 is H or PG-Y—R2—X—; R6 is H or PG-Y—R213 X—; PG is a polymerizable group; X is absent, O or S; Y is absent, O, S, an ester, amide or urethane group; the bisacylphosphine oxide having at least one PG-Y—R2—X group and X and/or Y being absent if R2 is absent.

Abstract: The invention relates to compositions, polymerizable by ring-opening metathesis, which contain (a) at least one monomer and/or oligomer which is polymerizable by ring-opening metathesis polymerization, (b) at least one filler and (c) at least one initiator for the ring-opening metathesis polymerization. The compositions are characterized in that the initiator is chemically or physically bound to the filler.

Abstract: To provide a dental restorative material composition using an organic-inorganic composite filler having excellent surface smoothness like a natural tooth, low polymerization shrinkage, excellent X-ray contrast imaging property, similar transparency to that of a natural tooth, and no variation of transparency before and after the composition is hardened, the dental restorative material composition includes (a) a (meth)acrylate monomer, (b) an organic-inorganic composite filler having an average particle diameter of 5 to 50 ?m which is made by mixing a (meth)acrylate monomer and a fine particle filler having an average primary particle diameter of 0.005 to 0.3 ?m and having X-ray impermeability, (c) a fine particle filler having an average primary particle diameter of 0.005 to 0.04 ?m, and (d) a photopolymerization initiator.

Abstract: A bone cement is shown that includes a monomer, and a non-reactive substance that is fully miscible with the monomer. A resulting cured bone cement exhibits desirable properties such as modification in a stiffness of the material. Modified properties such a stiffness can be tailored to match bone properties and reduce an occurrence of fractures adjacent to a region repaired with bone cement. One example includes adjacent vertebral body fractures in vertebroplasty procedures.

Abstract: The invention provides an infiltrant for dental application that comprises crosslinking monomers, having a penetration coefficient PC>50 cm/s. In accordance with the invention the infiltrant comprises at least one nanoscale radiopaque filler and/or radiopaque organic compound, whilst ensuring sufficient contrast to surrounding tooth and bone tissue in X-ray diagnostics.

Abstract: Dental materials which contain a radically polymerizable organic binder, at least one radical polymerization initiator and at least one radical polymerization accelerator, both the initiator and the accelerator each having at least one radically polymerizable group.

Abstract: A polymethylmethacrylate bone cement with a liquid monomer component and a solid component contains in the monomer liquid, for example, 0.001-1.00 mass percent of a dye or dye mixture that is insoluble or poorly soluble in methacrylic acid methylester and, for example, 0.001-2.00 mass percent of a synthetically produced, protein-free, hydrophobic, low molecular or oligomeric solubilizer for the dye or dye mixture. The solubilizer preferably is liquid or pasty at room temperature. The monomer liquid is translucent at room temperature. Preferably, 0.001-1.00 mass percent of a dye or dye mixture that is insoluble or poorly soluble in methacrylic acid methylester and, preferably, 0.001-2.00 mass percent of a synthetically produced, protein-free, hydrophobic, low molecular or oligomeric solubilizer that is liquid or pasty at room temperature are homogeneously dissolved in the polymethacrylate or polymethylacrylate of the powder component.

Abstract: The present invention features ionomer compositions containing nanozirconia fillers. The compositions can be used in a variety of dental and orthodontic applications, for example, as adhesives, cements, restoratives, coatings and sealants.

Abstract: A composition of matter comprising a water-swellable IPN or semi-IPN including a hydrophobic thermoset or thermoplastic polymer and an ionic polymer, articles made from such composition and methods of using such articles. The invention also includes a process for producing a water-swellable IPN or semi-IPN from a hydrophobic thermoset or thermoplastic polymer including the steps of placing an ionizable monomer solution in contact with a solid form of the hydrophobic thermoset or thermoplastic polymer; diffusing the ionizable monomer solution into the hydrophobic thermoset or thermoplastic polymer; and polymerizing the ionizable monomers to form a ionic polymer inside the hydrophobic thermoset or thermoplastic polymer, thereby forming the IPN or semi-IPN.