Phosphorus- Or Sulfur-containing Reactant Patents (Class 528/321)
-
Patent number: 11485835Abstract: An impact-modified composition and a method of making an impact-modified composition are provided. In an embodiment, the method includes reacting a phosphazene material with an acrylamide material to form a functionalized phosphazene material; initiating a polymerization reaction on a reaction mixture comprising the functionalized phosphazene material and one or more monomers to form an impact-modified phosphazene material; and adding the an impact-modified phosphazene material to a polymeric material.Type: GrantFiled: January 2, 2020Date of Patent: November 1, 2022Assignee: International Business Machines CorporationInventors: Brandon M. Kobilka, Joseph Kuczynski, Jacob T. Porter, Jason T. Wertz
-
Patent number: 11377546Abstract: The present invention relates to a resin composition comprising an (A) maleimide compound having a saturated or unsaturated divalent hydrocarbon group, and a thermoplastic resin.Type: GrantFiled: July 18, 2017Date of Patent: July 5, 2022Assignee: SHOWA DENKO MATERIALS CO., LTD.Inventors: Takao Tanigawa, Tetsuroh Irino, Minoru Kakitani, Kouji Morita
-
Patent number: 10619008Abstract: Aliphatic polyimides are synthesized by a reaction of 2 moles of an unsaturated monoanhydride or an unsaturated diacid with both one mole of a diamine and one mole of a monoamine. Imidization of intermediates so formed from those reactions resolve to 6 possible bicyclic imidic structures bridged by monoamidic or saturated hydrocarbon spans, more likely the latter. Bio-derived monomers are particularly useful in the synthesis of the aliphatic polyimides.Type: GrantFiled: April 23, 2015Date of Patent: April 14, 2020Assignee: PolyOne CorporationInventors: Yannan Duan, Roger W. Avakian
-
Patent number: 9902824Abstract: Disclosed is a process for production of a colored polyimide molded article including the steps of molding a polyamic acid solution composition containing a polyamic acid solution obtained from at least a tetracarboxylic acid component and a diamine component and a coloring precursor, or a polyimide solution composition containing a polyimide solution and a coloring precursor; and then thermally treating a molded product at 250° C. or higher.Type: GrantFiled: April 8, 2016Date of Patent: February 27, 2018Assignee: UBE INDUSTRIES, LTD.Inventors: Shyusei Ohya, Makoto Matsuo
-
Patent number: 9169354Abstract: The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents.Type: GrantFiled: February 6, 2012Date of Patent: October 27, 2015Assignee: Serina Therapeutics, Inc.Inventors: Kunsang Yoon, J. Milton Harris, Michael David Bentley
-
Publication number: 20150094447Abstract: The invention relates to polymers comprising NOS agonists and one or more monomers selected from the group consisting of lactide, glycolide and epsiloncaprolactone, wherein the NOS agonist is incorporated as repeating monomer units into the body or backbone of the polymer are disclosed. The NOS agonist may comprise one or more carboxylic acid groups and one or more alkylhydroxy groups. In another embodiment, the NOS agonist may comprise a carboxylic acid group and an alkylhydroxy group that can be joined to form a lactone containing cyclic ring. In another embodiment, the NOS agonist comprises HMG CoA reductase inhibitor or statin.Type: ApplicationFiled: November 14, 2014Publication date: April 2, 2015Applicant: PALMETTO PHARMACEUTICALS LLCInventor: Wayne H. KAESEMEYER
-
Publication number: 20150087777Abstract: A multi-stage process and system for formation of a polyarylene sulfide is described. A first polymerization stage of the formation process can include reaction of a sulfide monomer with a dihaloaromatic monomer to form a prepolymer. A second polymerization stage can include further polymerization of the prepolymer with a sulfur-containing monomer and a dihaloaromatic monomer to form a low halogen content polyarylene sulfide. The amount of sulfur utilized in the second polymerization stage is a low fraction of the total amount of sulfur utilized in the multi-stage process.Type: ApplicationFiled: September 9, 2014Publication date: March 26, 2015Inventor: Hendrich Alvarez Chiong
-
Publication number: 20150064106Abstract: Biodegradable polyphosphazene polymers containing pyrrolidone side groups, and the biomedical use of such polyphosphazene polymers are disclosed.Type: ApplicationFiled: November 7, 2014Publication date: March 5, 2015Inventors: Alexander Andrianov, Bryan Roberts
-
Patent number: 8962769Abstract: The present invention relates to novel polyimidothioethers-inorganic nanoparticle hybrid material, which exhibit good surface planarity, thermal dimensional stability, tunable refractive index, and high optical transparency upon forming into films. The present invention also relates to polyimidothioethers which is an intermediate for preparing the present hybrid material, and their preparation.Type: GrantFiled: June 27, 2012Date of Patent: February 24, 2015Assignee: National Taiwan UniversityInventors: Guey-Sheng Liou, Chia-Liang Tsai, Hung-Ju Yen, Wen-Chang Chen, Wen-Yen Chiu, Yang-Yen Yu
-
Patent number: 8957163Abstract: Provided is a polymer-based detergent builder which is capable of effectively suppressing deposition of a surfactant, and effectively preventing soil re-deposition, even in washing using high hardness water.Type: GrantFiled: March 23, 2007Date of Patent: February 17, 2015Assignee: Nippon Shokubai Co., Ltd.Inventors: Atsuro Yoneda, Akiko Hemmi
-
Publication number: 20150005468Abstract: The present invention generally relates to high permeability, UV cross-linkable copolyimide polymers and membranes for gas, vapor, and liquid separations, as well as methods for making and using these membranes. The invention provides a process for separating at least one gas from a mixture of gases using the high permeability copolyimide membrane or the UV cross-linked copolyimide membrane, the process comprising: (a) providing a high permeability copolyimide membrane or a UV cross-linked copolyimide membrane which is permeable to said at least one gas; (b) contacting the mixture on one side of the high permeability copolyimide membrane or the UV cross-linked copolyimide membrane to cause said at least one gas to permeate the membrane; and (c) removing from the opposite side of the membrane a permeate gas composition comprising a portion of said at least one gas which permeated said membrane.Type: ApplicationFiled: May 14, 2014Publication date: January 1, 2015Applicant: UOP LLCInventors: Zara Osman, Chunqing Liu, Angela N. Troxell, Carl W. Liskey
-
Publication number: 20140350127Abstract: The present disclosure provides colorant compounds and methods of isolation of the colorant compounds derived from a reaction of genipin and an amine. The colorant compositions comprise purified compounds (e.g., a purified polymer or a purified dimer) obtained from multiple fractioning by chromatography of the reaction resulting material. The purified polymer or dimer can be used as a colorant by itself or in combination with another colorant for imparting color to a food, a drug, a cosmetic, a medical device, and textile products.Type: ApplicationFiled: May 22, 2014Publication date: November 27, 2014Applicant: ECOFLORA S.A.S.Inventors: Esteban Vargas CANO, Luis Fernando Echeverri Lopez, Juan Fernando Gil Romero, Edwin Andrés Correa Garcés, Sandra Patricia Zapata Porras
-
Publication number: 20140309352Abstract: A curable polymer composition comprising: (A) a thermoset maleimide resin precursor component; and further comprising one or both of: (B) an arylsulphone-containing maleimide component; and (C) a polyarylpolymer thermoplastic toughening agent component, wherein in the absence of component (B), said component (C) comprises one or more maleimide pendant and/or end groups, and thermoset resins and composites derived therefrom.Type: ApplicationFiled: December 20, 2012Publication date: October 16, 2014Applicant: CYTEC INDUSTRIES INC.Inventors: Steven Richard Ward, Paul Mark Cross, Robin Maskell
-
Patent number: 8859714Abstract: Disclosed are new organic semiconductor materials prepared from polymers based on N-alkyl-2,2?-bithiophene-3,3?-dicarboximide (BTI) repeating units. Such polymers can exhibit desirable electronic properties and can possess processing advantages including solution-processability and/or good stability at ambient conditions.Type: GrantFiled: June 30, 2010Date of Patent: October 14, 2014Assignee: Northwestern UniversityInventors: Tobin J. Marks, Antonio Facchetti
-
Patent number: 8839960Abstract: The present disclosure relates to polymeric matrices composed of protected amine compound residues and membranes composed from such polymeric matrices. In particular, the present disclosure relates to a polymeric matrix comprising amine compound residues, acyl compound residues and protected amine compound residues.Type: GrantFiled: December 21, 2010Date of Patent: September 23, 2014Assignee: General Electric CompanyInventor: Qingshan Jason Niu
-
Publication number: 20140272600Abstract: The invention relates to a BA diblock or BAB triblock copolymer, in which the A block is a non-substituted poly-oxyethylene chain having a mean molecular weight that is higher than 100 kDa and the B block is an anionic polymer which can be prepared using one or more monomers selected from among the vinyl monomers and derivatives thereof, said monomers being substituted with a (trifluoromethylsulfonyl)imide (TFSI) anion. The invention also relates to the uses of such a copolymer, in particular for preparing an electrolyte composition for lithium metal polymer (LMP) batteries.Type: ApplicationFiled: September 5, 2012Publication date: September 18, 2014Inventors: Renaud Bouchet, Abdelmaula Aboulaich, Sébastien Maria, Trang Phan, Didier Gigmes, Denis Bertin, Rachid Meziane, Jean-Pierre Bonnet, Michel Armand
-
Patent number: 8796672Abstract: Disclosed are new semiconductor materials prepared from perylene-imide copolymers. Such polymers can exhibit high n-type carrier mobility and/or good current modulation characteristics. In addition, the compounds of the present teachings can possess certain processing advantages such as solution-processability and/or good stability at ambient conditions.Type: GrantFiled: February 5, 2009Date of Patent: August 5, 2014Assignees: Polyera Corporation, BASF SEInventors: Antonio Facchetti, He Yan, Zhihua Chen, Marcel Kastler, Florian Doetz
-
Publication number: 20140179802Abstract: The present invention relates to a fiber comprising a biodegradable polymer which undergoes dimensional change upon injection in the human or animal body wherein the dimensional change is a reduction of the surface area to volume ratio of a factor 2 to 10. The fiber is sized for injection via a pharmaceutical syringe needle having a bore of at least 25 Gauge. The biodegradable polymer is an amorphous biodegradable polymer selected from the group of poly-hexamethylene carbonates or polyesteramides. The amorphous biodegradable polymer is a preferably a polyesteramide comprising alpha-amino acids, diols and dicarboxylic acids as building blocks. The invention further relates to the use of the fiber for the manufacturing of a medicament for the treatment of ophthalmic diseases. The invention also relates to a process for the manufacturing of the fiber comprising the following process steps; a. extruding a biodegradable polymer into a fiber fitting in a needle of at least 25 Gauge b.Type: ApplicationFiled: May 2, 2012Publication date: June 26, 2014Applicant: DSM IP ASSETS B.V.Inventors: Astrid Franken, George Mihov, Jens Christoph Thies
-
Patent number: 8748070Abstract: Provided is a thiol group-containing charge transporting material represented by the following general formula (1): F-[(G)a1-(X)a2—Y—SH]b??(1) wherein F represents an organic group derived from a charge transporting compound, G represents a divalent organic group having 1 to 5 carbon atoms, X represents a group selected from a —CO—O— group, an —O—CO— group, and an —O— group, Y represents a divalent organic group having 1 to 5 carbon atoms, a1 and a2 each independently represent 0 or 1, and b represents an integer of 1 or more and 6 or less.Type: GrantFiled: August 25, 2011Date of Patent: June 10, 2014Assignee: Fuji Xerox Co., Ltd.Inventors: Katsumi Nukada, Kenya Sonobe, Wataru Yamada, Takatsugu Doi, Tsuyoshi Miyamoto, Yuko Iwadate
-
Patent number: 8703879Abstract: A continuous process for the multistage drying and postcondensation of polyamide pellets in the solid phase comprises 1) carrying out the predrying process in a continuous drying apparatus which is operated in countercurrent mode or in crossflow mode with inert gas or steam, or with a mixture of inert gas and steam, using a pellet temperature in the range from 70 to 200° C., and 2) Carrying out the subsequent continuous postcondensation process in a separate vertical duct with moving bed at a pellet temperature in the range from 120 to 210° C., where the duct is operated in countercurrent mode with inert gas or steam, or with a mixture of inert gas and steam, the inert gas is introduced at least two sites along the duct, and from 15 to 90% of the inert gas is introduced at the base of the vertical duct and from 10 to 85% of the inert gas is introduced in the upper half below the surface of the pellets.Type: GrantFiled: June 19, 2009Date of Patent: April 22, 2014Assignee: BASF SEInventors: Wolfgang Loth, Faissal-Ali El-Toufaili, Achim Stammer, Gad Kory, Achim Gerstlauer, Jens Becker
-
Publication number: 20140097375Abstract: The present disclosure is directed to an elastic polymer having characteristics of swelling by absorbing liquid and, and applications of preparation of gel electrolyte and absorbing the liquid by the polymer. The polymer is obtained by binding a poly(oxyethlene) L-NHm with a compound R being one elected from the group consisting of an acid, an anhydride and a combination thereof.Type: ApplicationFiled: April 9, 2013Publication date: April 10, 2014Applicant: National Taiwan UniversityInventors: KUO-CHUNG HO, Jiang-Jen Lin, Rui-Xuan Dong, Chung-Te Liu, Sheng-Yen Shen, Hsin-Wei Chen, Po-Ta Shih
-
Publication number: 20140031289Abstract: The present invention relates to a thermosensitive phosphazene-based polymer having a degradation controllable ionic group, a use thereof, and a use thereof as a material for delivering bioactive substances. The phosphazene-based polymer according to the present invention has the thermosensitivity of showing the temperature-dependent sol-gel phase transition. Thus, it forms a gel phase at the body temperature when it is injected into the body to make it easy to control the release of bioactive substances such as drugs, and has the functional groups capable of making chemical bonds such as ionic bond, covalent bond, coordinate bond, etc. with drugs and thus is excellent in bearing the drugs. Since it can control the degradation rate depending on the kind of ionic group, it can selectively control the release time depending on the characteristics of drugs. Furthermore, it has an excellent biocompatibility and thus is very useful as a material for delivery of bioactive substances such as drugs, etc.Type: ApplicationFiled: August 8, 2012Publication date: January 30, 2014Applicant: Korea Institute of Science and TechnologyInventors: Soo-Chang SONG, Young-Min Kim
-
Publication number: 20130296501Abstract: The present invention relates to novel polyimidothioethers-inorganic nanoparticle hybrid material, which exhibit good surface planarity, thermal dimensional stability, tunable refractive index, and high optical transparency upon forming into films. The present invention also relates to polyimidothioethers which is an intermediate for preparing the present hybrid material, and their preparation.Type: ApplicationFiled: June 27, 2012Publication date: November 7, 2013Inventors: Guey-Sheng LIOU, Chia-Liang Tsai, Hung-Ju Yen, Wen-Chang Chen, Wen-Yen Chu, Yang-Yen Yu
-
Publication number: 20130281654Abstract: Disclosed are polymers with a complex branched structure (star- or tree-shaped) obtainable by polymerizing a bifunctional type AB monomer and/or type AA+BB monomers in the presence of: a) one or more polyamine and/or a polyacid and/or a polyalcohol and/or more generally a compound (such as POSS) having at least three functional groups such as amino, carboxylic acid or hydroxyl functions; b) one or more phosphorus containing molecules reacting with only one reactive group during the polymerization; c) optionally one or more organic acid and/or an amine and/or an alcohol having one or two functional groups.Type: ApplicationFiled: December 14, 2011Publication date: October 24, 2013Applicant: UNIVERSITA' DEGLI STUDI DI MILANOInventors: Giuseppe Di Silvestro, Yuan Cuiming, Marco Ortenzi, Hermes Farina, Tommaso Lugato, Luca Basilissi
-
Publication number: 20130261194Abstract: A polyphosphazene polymer which includes hydrophilic side groups and interacting side groups which are capable of bonding with a biological agent of interest. The bonding may be by non-covalent bonding.Type: ApplicationFiled: March 7, 2013Publication date: October 3, 2013Inventor: Alexander K. Andrianov
-
Publication number: 20130247991Abstract: Disclosed are certain polymeric compounds and their use as organic semiconductors in organic and hybrid optical, optoelectronic, and/or electronic devices such as photovoltaic cells, light emitting diodes, light emitting transistors, and field effect transistors. The disclosed compounds can provide improved device performance, for example, as measured by power conversion efficiency, fill factor, open circuit voltage, field-effect mobility, on/off current ratios, and/or air stability when used in photovoltaic cells or transistors. The disclosed compounds can have good solubility in common solvents enabling device fabrication via solution processes.Type: ApplicationFiled: March 15, 2013Publication date: September 26, 2013Inventors: Antonio Facchetti, Kap-Soo Cheon, Hualong Pan, Martin Drees
-
Patent number: 8541539Abstract: A method for preparing a water-soluble polyamide, includes copolymerizing reactive monomers including caprolactam; ethylene glycol bis(2-aminoethyl)ether or ethylene glycol bis(3-aminopropyl)ether; and 5-sulfoisophthalic acid monosodium salt, wherein a molar ratio of caprolactam:ethylene glycol bis(2-aminoethyl)ether or ethylene glycol bis(3 -aminopropyl)ether:5-sulfoisophthalic acid monosodium salt is about 0:1:1 to about 5:1:1, advantageously about 1.85:1:1. Copolymerizing takes place at a copolymerization temperature of about 222-250° C. and a copolymerization pressure of about 3 Bar. The method further includes maintaining a temperature of about 222-250° C. for about 2-3 hours under normal pressure after the copolymerization step. The water-soluble polyamide has a solubility in water of about 10-70%.Type: GrantFiled: December 29, 2008Date of Patent: September 24, 2013Assignee: Taiwan Textile Research InstituteInventors: Yu-Chi Tseng, Chin-Wen Chen, S-P Rwei
-
Patent number: 8501899Abstract: The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents.Type: GrantFiled: January 23, 2012Date of Patent: August 6, 2013Assignee: Serina Therapeutics, Inc.Inventors: Kunsang Yoon, J. Milton Harris, Michael David Bentley, Zhihao Fang, Tacey Viegas
-
Patent number: 8420771Abstract: Provided are a new pH-sensitive co-polymer prepared from polyethylene oxide and a method of preparing the same. The polyethylene oxide co-polymer includes repeating units expressed by the Chemical Formulas 1 and 2, and further includes at least one of repeating units expressed by the Chemical Formulas 3 through 6.Type: GrantFiled: February 26, 2009Date of Patent: April 16, 2013Inventors: Jung-Ahn Kim, Hyun-Oh Yoo
-
Publication number: 20130085256Abstract: Described herein are compositions including heterocyclic organic compounds based on fused thiophene compounds, polymers based on fused thiophene compounds, and methods for making the monomers and polymer along with uses in thin film-based and other devices.Type: ApplicationFiled: October 31, 2012Publication date: April 4, 2013Inventors: Mingqian He, Jianfeng Li, James Robert Matthews, Weijun Niu, Arthur L. Wallace
-
Patent number: 8383763Abstract: Sulfonated polymers are made by the direct polymerization of a sulfonated monomer to form the sulfonated polymers. The types of sulfonated polymers may include polysulfones or polyimides. The sulfonated polymers can be formed into membranes that may be used in proton exchange membrane fuel cells or as ion exchange membranes. The membranes formed from the sulfonated polymers exhibit improved properties over that of Nafion®. A heteropoly acid may be added to the sulfonated polymer to form a nanocomposite membrane in which the heteropoly acid is highly dispersed. The addition of a heteropoly acid to the sulfonated polymer increases the thermal stability of the membrane, enhances the conductivity above 100° C., and reduces the water uptake of the membrane.Type: GrantFiled: July 29, 2010Date of Patent: February 26, 2013Assignee: Virginia Tech Intellectual Properties, Inc.Inventors: James E. McGrath, Michael Hickner, Feng Wang, Yu-Seung Kim
-
Patent number: 8372315Abstract: A donor-acceptor (DA) ?-conjugated polymer with high charge transfer mobility has a plurality of D1kAD1k portions, where k is 1 or 2, D1 is a donor unit having at least one solubilizing side chain, and A is an acceptor unit, and the donor-acceptor (DA) ?-conjugated polymer has a plurality of D2m spacer sequences situated between the D1kAD1k portions, where m is 1 to 6 and D2 is a second donor unit where all atoms of the unit are coplanar in at least one conformation that the unit can assume. The DA ?-conjugated polymer can reflect a blue tinted green, deep green, or yellow tinted green color. The DA ?-conjugated polymers have space-charge limited (SCL) zero field hole mobilities of at least 1×10?6 cm2V?1s?1.Type: GrantFiled: May 26, 2010Date of Patent: February 12, 2013Assignee: University of Florida Research Foundation, Inc.Inventors: Pierre Marc Beaujuge, John R. Reynolds, Stefan Martin Ellinger
-
Patent number: 8283438Abstract: A process for the preparation of functional molecules using the thiol-ene coupling reaction and a process for the preparation of protected functional thiols, specifically thioesters is provided. The methods may be used to make functional polymers and other molecules. The method of making a functionalized polymer using a thiol-ene reaction comprises: providing a functionalized thioester having the following formula: wherein R is a functional group and COR? is a protecting group; cleaving the functionalized thioester, forming a functional thiol and an acyl group; providing a polymer having a pendant vinyl group; and reacting the polymer with the functional thiol whereby a functionalized polymer is formed, wherein the functional thiol is not isolated prior to reacting with the polymer.Type: GrantFiled: December 6, 2010Date of Patent: October 9, 2012Assignee: California Institute of TechnologyInventors: Ralph L. David, Julia A. Kornfield
-
Publication number: 20120248379Abstract: An intermediate transfer member includes a poly(amic acid amideimide), or a mixture of a poly(amic acid amideimide), a phosphate ester, an optional polysiloxane, and an optional conductive filler component.Type: ApplicationFiled: March 29, 2011Publication date: October 4, 2012Applicant: XEROX CORPORATIONInventors: Jin WU, Jonathan H. HERKO, Francisco J. LOPEZ, Kyle B. TALLMAN, Michael S. ROETKER, David W. MARTIN, Brian P. GILMARTIN
-
Publication number: 20120225116Abstract: Biodegradable polyphosphazene polymers containing pyrrolidone side groups, and the biomedical use of such polyphosphazene polymers are disclosed.Type: ApplicationFiled: May 14, 2012Publication date: September 6, 2012Inventors: Alexander K. Andrianov, Bryan E. Roberts
-
Publication number: 20120196215Abstract: Provided is a thiol group-containing charge transporting material represented by the following general formula (1): F-[(G)a1-(X)a2—Y—SH]b??(1) wherein F represents an organic group derived from a charge transporting compound, G represents a divalent organic group having 1 to 5 carbon atoms, X represents a group selected from a —CO—O— group, an —O—CO— group, and an —O— group, Y represents a divalent organic group having 1 to 5 carbon atoms, a1 and a2 each independently represent 0 or 1, and b represents an integer of 1 or more and 6 or less.Type: ApplicationFiled: August 25, 2011Publication date: August 2, 2012Applicant: FUJI XEROX CO., LTD.Inventors: Katsumi NUKADA, Kenya SONOBE, Wataru YAMADA, Takatsugu DOI, Tsuyoshi MIYAMOTO, Yuko IWADATE
-
Patent number: 8232344Abstract: According to the present invention, there can be provided a structure preventing the nonspecific adsorption, and a target substance-detecting element and a target substance-detecting kit. A first aspect of the present invention is a structure including: a substrate; and a membrane, present on the surface of the substrate, having a polymer of a monomer represented by the following General Formula (1) or (2): (wherein R represents H or CH3; x represents an integer of 2 to 5, and y represents an integer of 1 to 7, with the proviso that x+y=an integer of 3 to 10), and (wherein R1?H or CH3, and R2 represents O or NH; a represents an integer of 2 to 5, and b represents an integer of 1 to 7, with the proviso that a+b=an integer of 3 to 10).Type: GrantFiled: June 24, 2008Date of Patent: July 31, 2012Assignee: Canon Kabushiki KaishaInventors: Kazuhiro Ban, Masato Minami
-
Publication number: 20120183493Abstract: The present invention relates to polymers comprising monomer units derived from captopril, and their use in the treatment or prevention of collagen deposition, fibrosis, scars, burns, or unwanted tissue formation. The present invention further relates to processes for the preparation of said polymers and to pharmaceutical compositions and medical products comprising the polymers. Also encompassed by the present invention are polymers comprising monomer units derived from other ACE inhibitors such as zofenopril, alacepril, rentiapril or pivalopril, or from vasopeptidase inhibitors such as fasidotrilat, omapatrilat or ilepatril.Type: ApplicationFiled: May 11, 2010Publication date: July 19, 2012Applicant: PharmaPatents Global Ltd.Inventor: Keith McCormack
-
Publication number: 20120172455Abstract: A polyphosphazene polymer which includes hydrophilic side groups and interacting side groups which are capable of bonding with a biological agent of interest. The bonding may be by non-covalent bonding.Type: ApplicationFiled: April 25, 2011Publication date: July 5, 2012Inventor: Alexander K. Andrianov
-
Patent number: 8211335Abstract: A method is provided, comprising: copolymerizing a monomer comprising at least two amide groups, a monomer of formula (a) and a sulfonic acid or salt monomer, wherein R1 is CH3 or H. A polymer made by the method is provided. A method for coating an electrode is provided, comprising: providing an electrode; providing a solution of a free radical initiator, a monomer comprising at least two amide groups, a monomer of formula (a) and a sulfonic acid or salt monomer; wetting the electrode with the solution; and heating the wetted electrode; whereby the monomer comprising at least two amide groups, the monomer of formula (a), and the sulfonic acid or salt monomer are copolymerized; wherein R1 is CH3 or H. An electrode coated by the method is provided.Type: GrantFiled: August 31, 2009Date of Patent: July 3, 2012Assignee: General Electric CompanyInventors: Zhigang Deng, Hai Yang, Liping Zheng, Su Lu, Lin Chen, Hui Liu, Wei Cai, Xianguo Yu
-
Publication number: 20120152822Abstract: The present disclosure relates to polymeric matrices composed of protected amine compound residues and membranes composed from such polymeric matrices. In particular, the present disclosure relates to a polymeric matrix comprising amine compound residues, acyl compound residues and protected amine compound residues.Type: ApplicationFiled: December 21, 2010Publication date: June 21, 2012Inventor: Qingshan Jason Niu
-
Publication number: 20120136123Abstract: The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents.Type: ApplicationFiled: February 6, 2012Publication date: May 31, 2012Applicant: Serina Therapeutics, Inc.Inventors: J. Milton Harris, Michael David Bentley, Kunsang Yoon
-
Patent number: 8182830Abstract: Described herein are hydrogen sulfide (H2S) generating polymers and polymer systems suitable for coating or forming medical devices and methods for making and using the same. More specifically, described are H2S generating polymers comprising at least one thioamide group. The H2S generating polymers can provide controlled site-specific release of H2S once implanted at or within the target surgical site by hydrolysis of the thioamide group in physiological media. The H2S generating polymers can be coated onto a medical device, formed into a medical device or combined with one or more other polymers to form a polymer system. Also described are methods of treating restenosis and inflammation and promoting vasodilation utilizing such medical devices.Type: GrantFiled: January 5, 2010Date of Patent: May 22, 2012Assignee: Medtronic Vascular, Inc.Inventors: Mingfei Chen, Christopher Storment, David Shumaker
-
Patent number: 8173999Abstract: A method is provided for modifying a poly(arylene vinylene) or poly(heteroarylene vinylene) precursor polymer having dithiocarbamate moieties by reacting it with an acid and further optionally reacting the acid-modified polymer with a nucleophillic agent. Also provided are novel polymers and copolymers bearing nucleophillic side groups which are useful as components of electronic devices, e.g. in the form of thin layers.Type: GrantFiled: July 31, 2008Date of Patent: May 8, 2012Assignees: IMEC, Universiteit HasseltInventors: Laurence Lutsen, Dirk Vanderzande, Fateme Banishoeib
-
Patent number: 8110651Abstract: The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents.Type: GrantFiled: January 12, 2009Date of Patent: February 7, 2012Assignee: Serina Therapeutics, Inc.Inventors: Kunsang Yoon, J. Milton Harris, Michael David Bentley
-
Patent number: 8106142Abstract: Polyacetylinic oligomers suitable for high-temperature polymer-matrix composites are provided. The polyacetylinic oligomers have the formula: D-A-D wherein D is an endcap including at least one crosslinking functionality; and A is backbone selected from the group consisting of imidesulfone; ether; ethersulfone; amide; imide; ester; estersulfone; etherimide; amideimide; oxazole; oxazole sulfone; thiazole; thiazole sulfone; imidazole; and imidazole sulfone. At least one ethynyl functional group, however, is incorporated into the backbone such that crosslinking is not only realized at the endcaps but also at the ethynyl groups within the backbone of the oligomer itself.Type: GrantFiled: October 20, 2009Date of Patent: January 31, 2012Assignee: The Boeing CompanyInventors: Thomas K. Tsotsis, Norman R. Byrd
-
Patent number: 8101706Abstract: The present disclosure provides copolymers of 2-substituted-2-oxazolines possessing two or three reactive functional groups which are also chemically orthogonal. The copolymers described may be random copolymers, block copolymers or a mixture of random and block copolymer configurations. Furthermore, the present disclosure provides novel methods for synthesizing the above polymers and for conjugating to molecules such as targeting, diagnostic and therapeutic agents.Type: GrantFiled: May 25, 2010Date of Patent: January 24, 2012Assignee: Serina Therapeutics, Inc.Inventors: Kunsang Yoon, Michael David Bentley, J. Milton Harris, Zhihao Fang, Tacey Viegas
-
Publication number: 20110319587Abstract: A method for producing a polyarylene sulfide resin includes allowing a polyhaloaromatic compound (a), an alkali metal hydrosulfide (b), and an organic acid alkali metal salt (c) to react with each other in the presence of a solid alkali metal sulfide and an aprotic polar organic solvent, wherein the reaction is conducted using the organic acid alkali metal salt (c) in a ratio of 0.01 moles or more and less than 0.9 moles relative to a total of 1 mole of the solid alkali metal sulfide and the alkali metal hydrosulfide (b) in a state where the amount of water existing in the reaction system is 0.02 moles or less relative to 1 mole of the aprotic polar organic solvent. Thus, it is possible to provide a method for producing a polyarylene sulfide resin with which high productivity is achieved on an industrial scale, and the molecular weight of the resulting polyarylene sulfide resin can be significantly increased.Type: ApplicationFiled: November 10, 2009Publication date: December 29, 2011Applicant: DIC CorporationInventor: Toshio Hinokimori
-
Patent number: 8063168Abstract: An oligomer having di-phenylethynyl endcaps is disclosed. The capped oligomer has the formula: D-A-D wherein D is a di-phenylethynyl endcap; and A is an oligomer selected from the group consisting of imidesulfone; ether; ethersulfone; amide; imide; ester; estersulfone; etherimide; amideimide; oxazole; oxazole sulfone; thiazole; thiazole sulfone; imidazole; and imidazole sulfone.Type: GrantFiled: February 6, 2009Date of Patent: November 22, 2011Assignee: The Boeing CompanyInventors: Thomas K. Tsotsis, Norman R. Byrd
-
Publication number: 20110213117Abstract: Disclosed are new organic semiconducting polymers. The polymers disclosed herein can exhibit high carrier mobility and/or efficient light absorption/emission characteristics, and can possess certain processing advantages such as solution-processability and/or good stability at ambient conditions.Type: ApplicationFiled: November 6, 2009Publication date: September 1, 2011Applicants: Polyera Corporation, BASF SEInventor: Antonio Facchetti