Abstract: A dextran derivative gel in particle form for use in the separation of substances according to their molecular size and/or electrical charge by means of gel-chromatographic and/or ion exchange techniques is disclosed which gel comprises a copolymerizate obtained by the free-radical copolymerization of a dextran derivative containing vinyl and/or substituted vinyl groups with (a) a divinyl compound of the formula ##STR1## wherein R' and R" are equal or different and each represent hydrogen or methyl and X is ##STR2## --SO.sub.2 -- or the group ##STR3## wherein n is an integer from 1 to 6, inclusive, and optionally (b) a low-molecular weight monovinyl compound.
Type:
Grant
Filed:
November 29, 1976
Date of Patent:
June 13, 1978
Assignee:
Pharmacia Fine Chemicals AB
Inventors:
Haldor Ingemar Johansson, Dag Torsten Lindstrom, John Lennart Soderberg
Abstract: A novel affinity matrix material for trypsin and trypsin-like enzymes is disclosed. Methods employing this material to isolate and/or purify crude extracts containing trypsin and trypsin-like enzymes and to store the purified enzymes obtained are also disclosed.
Type:
Grant
Filed:
November 21, 1974
Date of Patent:
April 26, 1977
Assignee:
Xerox Corporation
Inventors:
A. Hirotoshi Nishikawa, Harry F. Hixson, Jr.
Abstract: A reactive matrix comprises a co-enzyme chemically attached to a water insoluble organic polymeric support material. The reactive matrix may be used in a process for the separation of mixtures containing a plurality of enzymes.
Type:
Grant
Filed:
September 4, 1975
Date of Patent:
March 15, 1977
Inventors:
Peter Duncan Goodearl Dean, Christopher Robin Lowe
Abstract: A reactive matrix comprises a co-enzyme chemically attached to a water insoluble organic polymeric support material. The reactive matrix may be used in a process for the separation of mixtures containing a plurality of enzymes.
Type:
Grant
Filed:
September 4, 1975
Date of Patent:
March 15, 1977
Inventors:
Peter Duncan Goodearl Dean, Christopher Robin Lowe
Abstract: A reactive matrix comprises a co-enzyme chemically attached to a water insoluble organic polymeric support material. The reactive matrix may be used in a process for the separation of mixtures containing a plurality of enzymes.
Type:
Grant
Filed:
September 2, 1975
Date of Patent:
March 15, 1977
Inventors:
Peter Duncan Goodearl Dean, Christopher Robin Lowe
Abstract: A reactive matrix comprises a co-enzyme chemically attached to a water insoluble organic polymeric support material. The reactive matrix may be used in a process for the separation of mixtures containing a plurality of enzymes.
Type:
Grant
Filed:
September 2, 1975
Date of Patent:
March 15, 1977
Inventors:
Peter Duncan Goodearl Dean, Christopher Robin Lowe
Abstract: A reactive matrix comprises a co-enzyme chemically attached to a water insoluble organic polymeric support material. The reactive matrix may be used in a process for the separation of mixtures containing a plurality of enzymes.
Type:
Grant
Filed:
September 4, 1975
Date of Patent:
March 15, 1977
Inventors:
Peter Duncan Goodearl Dean, Christopher Robin Lowe
Abstract: A reactive matrix comprises a co-enzyme chemically attached to a water insoluble organic polymeric support material. The reactive matrix may be used in a process for the separation of mixtures containing a plurality of enzymes.
Type:
Grant
Filed:
September 4, 1975
Date of Patent:
March 8, 1977
Inventors:
Peter Duncan Goodearl Dean, Christopher Robin Lowe
Abstract: A reactive matrix comprises a co-enzyme chemically attached to a water insoluble organic polymeric support material. The reactive matrix may be used in a process for the separation of mixtures containing a plurality of enzymes.
Type:
Grant
Filed:
September 2, 1975
Date of Patent:
March 8, 1977
Inventors:
Peter Duncan Goodearl Dean, Christopher Robin Lowe
Abstract: Nontoxic coloring compositions which comprise optically chromophoric groups attached via sulfonamido linkages to nondegradable chemical molecules having molecular dimensions which substantially prevent their absorption from the gastrointestinal tract are disclosed. The colorings find primary applications as food colors.