The Ring Oxygens Are In The 1,3-positions Of The Hetero Ring (e.g., 1,3 Dioxane, Etc.) Patents (Class 549/369)
  • Publication number: 20100056783
    Abstract: Novel process for the preparation of statins and their pharmaceutically acceptable salts thereof represented by the general formula-(1) through novel intermediate compounds of general formula-(4).
    Type: Application
    Filed: October 5, 2007
    Publication date: March 4, 2010
    Inventors: Manne Satyanarayana Reddy, Srinivasan Thirumalai Rajan, Maramreddy Sahadeva Reddy
  • Patent number: 7662959
    Abstract: A compound having the structure: w-A-x-CY—Z(CF3), where CY is cyclohexane or substituted cyclohexane, exemplified by 4-trifluoromethyl-4-methylcarboxy-4?-propyl-1,1?-(bi)cyclohexane.
    Type: Grant
    Filed: January 7, 2008
    Date of Patent: February 16, 2010
    Assignee: Air Products and Chemicals, Inc.
    Inventors: Gauri Sankar Lal, Michael Ulman, David Allen Roberts, Wade Hampton Bailey, William Franklin Burgoyne
  • Patent number: 7638256
    Abstract: Silicon compounds having fluorinated hemiacetal structure are provided. Silicone resins having the same structure have an appropriate acidity to enable formation of a finer pattern by minimizing the pattern collapse by swelling, exhibit improved resistance to the etching used in the pattern transfer to an organic film, and are thus suited for use in resist compositions for the bilayer process.
    Type: Grant
    Filed: July 6, 2006
    Date of Patent: December 29, 2009
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Takeshi Kinsho, Takeru Watanabe, Mutsuo Nakashima, Yoshitaka Hamada
  • Publication number: 20090309066
    Abstract: The invention relates to a liquid-crystalline medium based on a mixture of dielectrically negative, polar compounds which comprises at least one compound of the formula I in which the parameters have the meanings indicated in claim 1, to the use thereof in an electro-optical display, particularly in an active-matrix display based on the VA, ECB, PALC, FFS or IPS effect, and to displays of this type.
    Type: Application
    Filed: July 17, 2007
    Publication date: December 17, 2009
    Inventors: Melanie Klasen-Memmer, Georg Bernatz, Izumi Saito, Matthias Bremer, Lars Lietzau, Volker Reiffenrath
  • Patent number: 7629476
    Abstract: The invention relates to a method for preparing 2,5-dimethylphenylacetic acid by converting p-xylene with chloroacetyl chloride into 2-chloro-1-(2,5-dimethylphenyl)ethanone, which is reacted with the compound of the formula (II) to give the compound of the formula (III), which is then rearranged to give a mixture of the compounds (IV) and (V), which is then hydrolyzed to 2,5-dimethylphenylacetic acid.
    Type: Grant
    Filed: February 18, 2009
    Date of Patent: December 8, 2009
    Assignee: Bayer Cropscience AG
    Inventor: Thomas Himmler
  • Patent number: 7612243
    Abstract: The present invention relates to cyclopenta[b]naphthalene derivatives to the use thereof in liquid-crystalline or mesogenic media, to liquid-crystalline or mesogenic media comprising at least one of these cyclopenta[b]naphthalene derivatives, and to electro-optical display elements containing these liquid-crystalline or mesogenic media.
    Type: Grant
    Filed: October 31, 2007
    Date of Patent: November 3, 2009
    Assignee: Merck Patent GmbH
    Inventors: Lars Lietzau, Matthias Bremer, Melanie Klasen-Memmer, Michael Heckmeier
  • Publication number: 20090156839
    Abstract: The invention relates to a method for preparing 2,5-dimethylphenylacetic acid by converting p-xylene with chloroacetyl chloride into 2-chloro-1-(2,5-dimethylphenyl)ethanone, which is reacted with the compound of the formula (II) to give the compound of the formula (III), which is then rearranged to give a mixture of the compounds (IV) and (V), which is then hydrolyzed to 2,5-dimethylphenylacetic acid.
    Type: Application
    Filed: February 18, 2009
    Publication date: June 18, 2009
    Applicant: BAYER CROPSCIENCE AG
    Inventor: Thomas HIMMLER
  • Patent number: 7531695
    Abstract: The present invention is directed to compounds having the structure (I) wherein R1, R2, R3, R4, R5 and m are as defined herein. The compounds of this invention are novel therapeutic agents for the treatment of cancer, metabolic diseases and skin disorders in mammalian subjects. These compounds are also useful modulators of gene expression. They exert their activity by interfering with certain cellular signal transduction cascades. The compounds of the invention are thus also useful for regulating cell differentiation and cell cycle processes that are controlled or regulated by various hormones or cytokines. In particular, the invention relates to compounds that induce apoptosis of cancer cells and therefore may be used for the treatment or prevention of cancer, including advanced cancers and pre-cancerous cells. The invention also discloses pharmaceutical compositions and methods of treatment of disease in mammals.
    Type: Grant
    Filed: June 3, 2004
    Date of Patent: May 12, 2009
    Assignee: Auspex Pharmaceutical, Inc
    Inventors: Borcherng Hong, Sepehr Sarshar, Bruno Tse
  • Publication number: 20090065739
    Abstract: A compound represented by formula (1): wherein R1 is hydrogen or alkyl having 1 to 20 carbons, in which in the alkyl, arbitrary —CH2— may be replaced by —O—, —S—, —COO—, —CH?CH— or —C?C—, and arbitrary hydrogen may be replaced by halogen or alkyl having 1 to 3 carbons; ring A1, ring A2, ring A3, ring A4 and ring A5 are each independently a benzene ring, a piperidine ring, a tetrahydropyrane ring or a dioxane ring, in which in the rings, arbitrary hydrogen may be replaced by halogen, alkyl having 1 to 3 carbons, alkoxy having 1 to 3 carbons or halogenated alkyl having 1 to 3 carbons, and —CH? may be replaced by —N?; Z1, Z2, Z4, Z5 and Z6 are each independently a single bond, —COO— or —CF2O—; Z3 is a single bond or —CF2O—, and in the case where Z3 is a single bond, ring A3 is a ring represented by formula (RG-5), or L1 and L2 are both fluorine, or at least one of Z1, Z2, Z4, Z5 and Z6 is —CF2O—; L1, L2, L3 and L4 are each independently hydrogen or halogen; X1 is hydrogen, halogen, —C?N, —N?C?S, —C?C—C?N, —S
    Type: Application
    Filed: August 21, 2008
    Publication date: March 12, 2009
    Applicants: CHISSO CORPORATION, CHISSO PETROCHEMICAL CORPORATION
    Inventors: Yasuhiro HASEBA, Masayuki SAITO
  • Patent number: 7482044
    Abstract: Disclosed are compounds of formula I and dielectrically positive liquid crystalline media comprising a dielectrically positive component, component A, comprising a dielectrically positive compound of formula I, and optionally a second dielectrically positive component, component B, comprising one or more dielectrically positive compounds having a dielectric anisotropy of more than 3, and optionally a dielectric neutral component, component C, as well as to liquid crystal displays comprising these media, especially to active matrix displays and in particular to TN and to IPS displays.
    Type: Grant
    Filed: April 6, 2007
    Date of Patent: January 27, 2009
    Assignee: Merck Patent Gesellschaft Mit Beschrankter Haftung
    Inventors: Markus Czanta, Melanie Klasen-Memmer, Lars Lietzau
  • Publication number: 20090012319
    Abstract: The invention provides a process for the preparation of 2-substituted-derivatives of estrone and estradiol. The invention also provides several novel compounds, which can be intermediates in the process, and processes to prepare these novel compounds. The invention also provides 2-alkoxy-estrone, 2-alkoxy-estradiol or mixtures thereof essentially free from other estrogenic intermediates.
    Type: Application
    Filed: August 1, 2005
    Publication date: January 8, 2009
    Applicant: N.V. Organon
    Inventors: Johannaes Stoelwinder, Nicolaas Elisabeth Moers
  • Publication number: 20090012069
    Abstract: Disclosed are novel compounds of general formula (I) where the symbols are as defined in the specification, their tautomeric forms, their stereoisomers, their pharmaceutically acceptable salts, pharmaceutical compositions containing them, methods for their preparation, use of these compounds in medicine and the intermediates involved in their preparation. The compounds are useful in the treatment of diabetes and related diseases.
    Type: Application
    Filed: June 24, 2005
    Publication date: January 8, 2009
    Inventors: Braj Bhushan Lohray, Vidya Bhushan Lohray, Harikishore Pingali
  • Publication number: 20080234152
    Abstract: A compound which satisfies requirements for the annealing property and the lubricating property simultaneously and a process for producing the compound are provided. The compound is an alkylacetal compound represented by the following general formula (1) or (2). In the general formulae, R1 and R2 represent hydrocarbon groups, R3 to R8 represent hydrogen atom or hydrocarbon groups, i and j represent integers satisfying the relation that the sum of the integers is 8 to 98, and k represents 0 or 1.
    Type: Application
    Filed: February 22, 2005
    Publication date: September 25, 2008
    Applicant: Idemitsu Kosan Co., Ltd.
    Inventors: Haruhito Sato, Akihiro Shishikura
  • Publication number: 20080234501
    Abstract: The invention relates to a method for preparing 2,5-dimethylphenylacetic acid by converting p-xylene with chloroacetyl chloride into 2-chloro-1-(2,5-dimethylphenyl)ethanone, which is reacted with the compound of the formula (II) to give the compound of the formula (III), which is then rearranged to give a mixture of the compounds (IV) and (V), which is then hydrolyzed to 2,5-dimethylphenylacetic acid.
    Type: Application
    Filed: January 22, 2005
    Publication date: September 25, 2008
    Applicant: BAYER CROPSCIENCE AG
    Inventor: Thomas Himmler
  • Publication number: 20080207927
    Abstract: A process for the production of glycerol acetals of aldehydes selected from the group consisting of isobutyraldehyde, 2-ethylhexyl aldehyde, furfuryl aldehyde and benzaldehyde, in which glycerol is reacted with one or more of those aldehydes in the absence of organic solvents and in the presence of phosphoric acid as catalyst, the molar ratio of glycerol to aldehyde(s) being between 1:1 to 1:1.2.
    Type: Application
    Filed: September 27, 2007
    Publication date: August 28, 2008
    Inventors: Setsuo Sato, Alexssander Shigueru Araujo, Miriam Miyano
  • Publication number: 20080167482
    Abstract: The instant invention relates to mesogenic compounds comprising a mesogenic group and one or more bulky end groups which each contain at least two ring elements, where two of these ring elements are linked to the C-atom No. 2 of a 1,3-dioxane-5-yl group by a direct bond or via a linking group, preferably the mesogenic group is linked to the C-atom No. 5 of the 1,3-dioxane-5-yl group and preferably the compounds are of formula I wherein the parameters are as specified in the text. This bulky end group preferably contains two or more rings, which each are bound to one and the same linking atom. The instant invention further relates to mesogenic media, preferably liquid crystal media showing a blue phase and their use in electro-optical light modulation elements and their respective use in displays, as well as to such devices.
    Type: Application
    Filed: July 14, 2005
    Publication date: July 10, 2008
    Applicant: MERCK PATENT GMBH
    Inventors: Louise Diane Farrand, Patricia Eileen Saxton, John Patrick
  • Patent number: 7354893
    Abstract: An acetal of formula I: is described in which the radicals R1 to R6 independently of one another are eac hydrogen, methyl, ethyl, n-propyl, isopropyl, n-butyl, isobutyl, sec-butyl or tert-butyl, n=0 or 1, and there is a single bond or double bond at the location of a broken line between two C atoms, any double bond present in the chain linking the aliphatic ring to the acetal group having the E or Z configuration, with the proviso that the number of double bonds incorporating a C atom of the aliphatic ring is 0 or 1, and the number of double bonds not incorporating a C atom of the aliphatic ring is 0 or 1.
    Type: Grant
    Filed: July 5, 2004
    Date of Patent: April 8, 2008
    Assignee: Symrise GmbH & Co., KG
    Inventor: Erich Dilk
  • Patent number: 7351452
    Abstract: A compound of formula (I) or a dimer thereof; where R1 and R2 are independently selected from optionally substituted alkyl, optionally substitituted alkenyl, optionally substituted alkynyl, a functional group or a group of sub-formula (i) —(O)m—(CH2)p—R7??(i) where m is 0 or 1; p is an integer of from 1 to 12; R7 is a group of formula —CqX2q+1 where q is an integer of from 1 to 12 and X is halogen such as fluoro, or R7 a group of sub-formula (ii) where k is an integer of from 1 to 10, R8, R10, and R12 and each R9 and R11 are independently selected from alkyl, alkenyl or aryl, such as lower alkyl and in particular methyl; provided that at least one of R1 or R2 is a group of sub-formula (i); R3, R4, R5 and R6 are independently selected from hydrogen or halogen, and in particular fluorine, n is 0 or 1, and A is a ring structure as specified. Compounds of formula (I) may have liquid crystal properties and/or be useful in liquid crystal devices.
    Type: Grant
    Filed: November 7, 2002
    Date of Patent: April 1, 2008
    Assignee: Qinetiq Limited
    Inventors: John W Goodby, Michael Hird, Kenneth J Toyne, Chu C Dong, Robert D. C Richards
  • Patent number: 7329637
    Abstract: The present invention is directed to a novel dioxin compound and the use of the novel compound in creating fragrances, and scents in items such as perfumes, colognes and personal care products.
    Type: Grant
    Filed: December 23, 2004
    Date of Patent: February 12, 2008
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Anthony T. Levorse, Jr., Brett D. Newirth, Manfred Pawlak
  • Patent number: 7321052
    Abstract: A process for the preparation of a fuel oil (diesel fuel or heating oil) composition which is a mixture of an alkanol tranesterified fatty acid ester triglyceride and an acetal of glycerol is described. The process preferably provides a prestep of the formation of at least some of the alkanol transesterified triglyceride containing the glycerol for use in the formation of the acetal of glycerol. The composition can also be formed from a reaction of 1,1-dimethoxy- or 1,1-diethoxyethane and glycerol to form the acetal in the alkanol transesterified triglyceride.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: January 22, 2008
    Assignee: Board of Trustees of Michigan State University
    Inventors: Dennis J. Miller, Lars Peereboom, Aspi K. Kolah, Navinchandra S. Asthana, Carl T. Lira
  • Patent number: 7291367
    Abstract: The invention relates to liquid-crystalline compounds of the formula (I) in which R1, R2, A1, A2, A3, A4, Z1, Z2, Z3, a, b and c have the meanings indicated in Claim 1, and to liquid-crystalline media comprising at least one compound of the (I) and to electro-optical displays containing a liquid-crystalline medium of this type.
    Type: Grant
    Filed: November 17, 2003
    Date of Patent: November 6, 2007
    Assignee: Merck Patent GmbH
    Inventors: Peer Kirsch, Alexander Hahn, Eike Poetsch, Volker Meyer, Michael Heckmeier, Melanie Klasen-Memmer, Georg Luessem, Christian Hock
  • Publication number: 20070247585
    Abstract: Disclosed are hexahydrodibenzofuran compounds of formula I, the preparation thereof, the use thereof as components in liquid-crystalline media, and to electro-optical display elements which contain the liquid-crystalline media according to the invention.
    Type: Application
    Filed: April 24, 2007
    Publication date: October 25, 2007
    Inventors: Axel Jansen, Andreas Taugerbeck, Melanie Klasen-Memmer
  • Patent number: 7271296
    Abstract: The invention relates to a process for preparing phytofluene of the formula I, where a) a phosphonium salt of the formula II is condensed with an aldehyde of the formula III in a Wittig reaction to give an acetal of the formula IV b) the condensation product of the formula IV is subjected to an acid-catalyzed acetal hydrolysis to give the aldehyde of the formula V c) and V is condensed in a further Wittig reaction with a phosphonium salt of the formula VI to give phytofluene where the radicals R1, R2 and R7, and X? and Y? have the meaning sated in the description.
    Type: Grant
    Filed: October 15, 2004
    Date of Patent: September 18, 2007
    Assignee: BASF Aktiengesellschaft
    Inventors: Hansgeorg Ernst, Klaus Henrich
  • Publication number: 20070194278
    Abstract: A composition includes at least one compound represented by the following Formula (1). In the Formula (1), R1 represents an alkyl group having 1 to 18 carbon atoms, R2 represents a hydrogen atom or a substituent, and R3 represents a substituent. m represents an integer of from 0 to 4, and n represents an integer of from 1 to 5.
    Type: Application
    Filed: February 21, 2007
    Publication date: August 23, 2007
    Inventors: Koji Takaku, Akihide Osaku
  • Patent number: 7189863
    Abstract: A process for producing a brominated acetal (represented by the formula 3) includes (a) brominating a trifluoromethyl-substituted acetophenone by Br2 in the presence of an alkylene diol. It is optional to produce a trifluoromethyl-substituted 2-alkoxyacetophenone derivative (represented by the formula 9) by (b) reacting the brominated acetal with a metal alkoxide, thereby converting the brominated acetal into an ether; and (c) hydrolyzing the ether in the presence of an acid catalyst to remove an acetal group from the ether, thereby producing the 2-alkoxyacetophenone derivative.
    Type: Grant
    Filed: February 6, 2006
    Date of Patent: March 13, 2007
    Assignee: Central Glass Company, Limited
    Inventors: Akihiro Ishii, Masatomi Kanai, Yokusu Kuriyama, Manabu Yasumoto, Kenjin Inomiya, Takashi Ootsuka, Koji Ueda
  • Patent number: 7097887
    Abstract: The use of a compound of formula (I) wherein R1 is an alkyl or alkenyl group, either of which may be optionally interposed with one or more oxygen or sulphur atoms, R2 is an alkyl or alkenyl group, Y? and Y? are independently selected from oxygen or sulphur, n is an integer from 1 to 5, X is a direct bond or a C1-4alkylene or C2-4alkenylene chain, and A is group comprising one or two rings which are independently selected from aryl, heterocylic or cycloalkyl rings, and when there are two rings, they are bonded together directly or by way of a C1-4alkylene or C2-4alkenylene group, for increasing the u.v. stability of a liquid crystal mixture. The compounds of formula (I) are u.v. stable and are useful in liquid crystal devices which are exposed to high levels of u.v. light such as phosphor display cells. Certain compounds are novel and these form a further aspect of the invention.
    Type: Grant
    Filed: July 10, 2002
    Date of Patent: August 29, 2006
    Assignee: QinetiQ Limited
    Inventors: Stephen M Kelly, Neil L Campbell, Warren L Duffy
  • Patent number: 7081279
    Abstract: Liquid crystalline compounds having a large negative ?? low viscosity, a large K33/K11 value, a small ??/?? and mutually excellent solubility even at low temperature, compositions containing at least one of the compounds and liquid crystal display devices containing such a liquid crystal compositions are disclosed.
    Type: Grant
    Filed: August 29, 2003
    Date of Patent: July 25, 2006
    Assignee: Chisso Corporation
    Inventors: Takashi Kato, Tomoyuki Kondo, Henry Bernhardt, Shuichi Matsui, Hiroyuki Takeuchi, Yasuhiro Kubo, Fusayuki Takeshita, Etsuo Nakagawa
  • Patent number: 7074462
    Abstract: The invention relates to compounds of the formula I and to a liquid-crystalline medium based on a mixture of polar compounds of positive dielectric anisotropy, characterized in that it comprises one or more compounds of the general formula I in which R, A1, A2, Z1, Y, Z, L1, L2 and m are as defined herein.
    Type: Grant
    Filed: September 22, 2000
    Date of Patent: July 11, 2006
    Assignee: Merck Patent GmbH
    Inventors: Matthias Bremer, Michael Heckmeier, Joachim Krause, Detlef Pauluth, Achim Götz, Brigitte Schuler
  • Patent number: 7074464
    Abstract: A compound represented by the formula (1). wherein Ra is alkyl having 1 to 10 carbon(s) and, in that alkyl, any of —CH2— may be replaced with —O—, —S—, —CO—, —CH?CH— or —C?C— or any of hydrogens may be replaced with halogen or —CN; A1, A2 and A3 are independently 1,4-cycolohexylene, 1,4-cyclohexenylene, 1,4-phenylene, naphthalene-2,6-diyl, 1,2,3,4-tetrahydronaphthalene-2,6-diyl, decahydronaphthalene-2,6-diyl or 1,4-bicyclo[2.2.2]octylene and, in such a ring, any —CH2— may be replaced with —O—, any —CH? may be replaced with —N? and any hydrogen may be replaced with halogen; Z1, Z2 and Z3 are independently a single bond, —(CH2)2—, —(CF2)2—, —COO—, —OCO—, —CH2O—, —OCH2—, —CF2O—, —OCF2—, —CH?CH—, —CF?CF—, —C?C—, —(CH2)4—, —(CH2)3O— or —O(CH2)3—; p and q are independently 0 or 1. Also provided is a liquid crystal composition containing the same and a liquid crystal display element containing the composition.
    Type: Grant
    Filed: May 13, 2004
    Date of Patent: July 11, 2006
    Assignees: Chisso Petrochemical Corporation, Chisso Corporation
    Inventor: Takashi Kato
  • Patent number: 7029730
    Abstract: The invention relates to CF2O-bridged cyclohexane derivatives, in particular compounds of formula (I), R1-(-A1-Z1-)k1-Q-CF2O-A2-(-Z3-A3-)K3-R2, wherein Q represents group (a); W1, W2 represent —CH2— and/or —O— independendy from each other, X1, X2, X3, X4 represent H, F, —CH3—CH2F—CH2F and/or —CF3 independently from each other, provided that at least one substituent X1, X2, X3 and/or X4 does not represent H, Z2 represents a simple bond, —CH2—CH2— or —CF2—CF2—, m represents 0 or 1 and R1, R2, A1, A2, A3, Z1, Z3, k1 and k3 have the meaning cited in the description. The invention further relates to liquid crystal substances such as optical and electro-optical display elements.
    Type: Grant
    Filed: May 2, 2002
    Date of Patent: April 18, 2006
    Assignee: Merck Patent GmbH
    Inventors: Peer Kirsch, Andreas Taugerbeck, Detlef Pauluth, Joachim Krause, Kazuaki Tarumi, Georg Lüssem
  • Patent number: 7014890
    Abstract: Compounds of the formula (I) in which the parameters are as defined herein, are suitable for use in liquid-crystal media and liquid-crystal displays which contain these media.
    Type: Grant
    Filed: June 9, 2003
    Date of Patent: March 21, 2006
    Assignee: Merck Patent GmbH
    Inventors: Matthias Bremer, Melanie Klasen-Memmer, Barbara Hornung, Wolfgang Schmidt, Rainer Wingen
  • Patent number: 7001647
    Abstract: A novel perfluoroallyloxy compound represented by general formula (I) and a liquid crystal composition containing the compound are disclosed.
    Type: Grant
    Filed: December 4, 2003
    Date of Patent: February 21, 2006
    Assignee: Asahi Denka Co., Ltd.
    Inventors: Hirokatsu Shinano, Takahiro Otsuka, Masatomi Irisawa
  • Patent number: 6962767
    Abstract: Acetal compounds in which a 5- or 6-membered ring acetal structure is connected to a norbornene structure through a linker represented by —(CH2)m— in which one hydrogen atom may be substituted with a hydroxyl or acetoxy group, and m is from 1 to 8 are novel. Using the acetal compounds as a monomer, polymers are obtained. A resist composition comprising the polymer as a base resin is sensitive to high-energy radiation and has excellent sensitivity, resolution, and etching resistance.
    Type: Grant
    Filed: December 10, 2002
    Date of Patent: November 8, 2005
    Assignee: Shin-Etsu Chemical Co., Ltd.
    Inventors: Takeru Watanabe, Takeshi Kinsho, Koji Hasegawa, Tsunehiro Nishi, Mutsuo Nakashima, Seiichiro Tachibana, Jun Hatakeyama
  • Patent number: 6933385
    Abstract: The invention relates to new protected 3,5-dihydroxy-2,2-dimethyl-valeroamides for the synthesis of epothilones and derivatives and process for the production and the use of the new compounds for the production of epothilones or epothilone derivatives.
    Type: Grant
    Filed: August 5, 2002
    Date of Patent: August 23, 2005
    Assignee: Schering AG
    Inventors: Jurgen Westermann, Johannes Platzek, Orlin Petrov
  • Patent number: 6908645
    Abstract: The invention relates to liquid-crystalline compounds of the formula I and to a liquid-crystalline medium based on a mixture of polar compounds, characterized in that it comprises one or more compounds of the general formula I in which R1, L1, L2, L3, L4, L5, L6, Z1, Z2, X, v and u are as defined in claim 1.
    Type: Grant
    Filed: September 30, 2003
    Date of Patent: June 21, 2005
    Assignee: Merck Patent GmbH
    Inventors: Peer Kirsch, Marc Lenges, Michael Heckmeier
  • Patent number: 6872502
    Abstract: A polymer for a chemically amplified negative photoresist and a photoresist composition are provided. A representative polymer of the invention is a compound of formula 5: wherein: R1 through R5 and R14 through R17 are defined as set fourth in the specification, and a, b, c, and d represent the mole ratios of each monomer, wherein a has a value of 0-0.5, b has a value of 0-0.9, c has a value of 0-0.3, and d has a value of 0-0.3, provided that a+b+c+d=1; and n represents the degree of polymerization of each polymer, and has a value of at least 2.
    Type: Grant
    Filed: March 7, 2002
    Date of Patent: March 29, 2005
    Assignee: Samsung SDI Co., Ltd.
    Inventors: Beom-Wook Lee, Ik-Chul Lim, Seung-Joon Yoo
  • Patent number: 6844032
    Abstract: The compound (1) having 2,3-bis(trifluoromethyl)-1,4-phenylene is stable chemically and has excellent miscibility with other liquid crystal compounds, large and negative dielectric anisotropy and proper optical anisotropy. A liquid crystal composition comprising the compound has large specific resistance and a large voltage holding ratio, and that the composition is useful for a liquid crystal display element.
    Type: Grant
    Filed: March 29, 2002
    Date of Patent: January 18, 2005
    Assignees: Chisso Corporation, Chisso Petrochemical Corporation
    Inventors: Kazutoshi Miyazawa, Takashi Kato, Yasuhiro Kubo, Kanetsugu Terashima
  • Publication number: 20040242905
    Abstract: Aldehydes containing a difluorooxymethylene bridge, of the general formula I
    Type: Application
    Filed: May 27, 2004
    Publication date: December 2, 2004
    Inventors: Eike Poetsch, Werner Binder, Volker Meyer, Stephen Gurtler, Juergen Eckstein, Michael Schwarz
  • Publication number: 20040229937
    Abstract: This invention relates to novel diaryl ureas, pharmaceutical compositions containing such compounds and the use of those compounds or compositions for treating hyper-proliferative and angiogenesis disorders, as a sole agent or in combination with cytotoxic therapies.
    Type: Application
    Filed: March 1, 2004
    Publication date: November 18, 2004
    Inventors: Jacques Dumas, Wendy Lee, Yuanwei Chen, Lila Adnane, William J. Scott, Sharad Verma, Jianqing Chen, Zhi Chen, Lin Yi
  • Patent number: 6808762
    Abstract: The present invention relates to oxabicyclooctanes of the general formula I. in which R1, R2, A1, A2, A3, A4, L1, L2, n1, n2 and n3 have the meanings specified in claim 1, and to their use in liquid-crystalline media.
    Type: Grant
    Filed: October 1, 2002
    Date of Patent: October 26, 2004
    Assignee: Merck Patent GmbH
    Inventors: Matthias Bremer, Michael Heckmeier, Melanie Klasen-Memmer, Harald Lannert
  • Patent number: 6759103
    Abstract: The invention relates to compounds of the formula (I) and also liquid-crystal mixtures comprising these compounds, and their use in liquid-crystal displays: in which R1 is H, F, CF3, OCF3, OCF2H, OCFH2, an alkyl radical or alkyloxy radical or an alkenyl radical or alkenyloxy radical, R2 is H, an alkyl radical or alkyloxy radical or an alkenyl radical or alkenyloxy radical, M1 and M2 are —C(═O)O—, —OC(═O)—, —CH2O—, —OCH2—, —OCF2—, —CF2O—, —C≡C—, —CH2CH2—, —CF2CF2—, —CF═CF—C(═O)O— or a single bond A1 and A2 are &agr;-1,4-diyl, unsubstituted or mono- or disubstituted by F; where &agr; is: phenylene cyclohexane, 1-cyclohexene, or 1,3-dioxane-2,5-diyl m and n are zero or 1; m+n=0 or 1 L1, L2, L3, L4 and L5 are H or F.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: July 6, 2004
    Assignee: Clariant Financi (BVI) Limited
    Inventors: Barbara Hornung, Wolfgang Schmidt, Rainer Wingen
  • Patent number: 6737125
    Abstract: Compounds of the formula (I), liquid-crystal mixtures comprising these compounds, and their use in liquid-crystal displays: in which R1 is H, F, CF3, OCF3, OCF2H, OCFH2, an alkyl radical or alkyloxy radical or an alkenyl radical or alkenyloxy radical; R2 is H, an alkyl radical or alkyloxy radical or an alkenyl radical or alkenyloxy radical M1 is —C(═O)O—, —OC(═O)—, —CH2O—, —OCH2—, —OCF2—, —CF2O—, —C≡C—, —CH2CH2—, —CF2CF2—, —CF═CFC(═O)O— or a single bond M2 is —C(═O)O—, —OC(═O)—, —CH2O—, —OCH2—, —CH2CH2—, —CF2CF2— or a single bond; A1 and A2 are &agr;-1,4-diyl, unsubstituted or mono- or disubstituted by F; where &agr; is: phenylene, cyclohexane, 1-cyclohexene or 1,3-dioxane-2,5-diyl; m and n are zero or 1; m+n=0 or 1 L1, L2, L3, L4 and L5 are H or F.
    Type: Grant
    Filed: September 12, 2002
    Date of Patent: May 18, 2004
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Barbara Hornung, Wolfgang Schmidt, Rainer Wingen
  • Patent number: 6730803
    Abstract: The &bgr;-keto ester compound, &bgr;-hydroxy acid compound and acetonide form of a 1,3-diol derivative of the formulas (I), (V) and (VIII) wherein each symbol is as defined in the specification, are useful as a synthetic intermediate for an epothilone derivative being developed as a pharmaceutical agent having an antitumor activity.
    Type: Grant
    Filed: September 30, 2002
    Date of Patent: May 4, 2004
    Assignee: Sumika Fine Chemicals Co., Ltd.
    Inventors: Mitsuhiro Iwasaki, Kiyoshi Sugi, Hideto Miyamoto, Nobushige Itaya
  • Publication number: 20040073049
    Abstract: The invention relates to a process for the preparation of a substituted alkene of formula (I) wherein R1, R2 and R3 are independently of each other a protecting group for a hydroxy group or hydrogen and R4 is phenyl which is unsubstituted or mono- or disubstituted by alkoxy, which alkene constitutes an intermediate for the preparation of discodermolide and discodermolide analogues.
    Type: Application
    Filed: August 22, 2003
    Publication date: April 15, 2004
    Inventors: Guido Koch, Olivier Loiseleur, Gottfried Sedelmeier
  • Publication number: 20040059137
    Abstract: The invention relates to a process for the preparation of compounds containing at least one —CF2—O— bridge in the molecule, in which
    Type: Application
    Filed: June 12, 2003
    Publication date: March 25, 2004
    Inventors: Peer Kirsch, Andreas Taugerbeck, Alexander Hahn
  • Patent number: 6692657
    Abstract: Liquid crystalline compounds having a large negative &Dgr;∈ low viscosity, a large K33/K11 value, a small &Dgr;∈/&Dgr;⊥ and mutually excellent solubility even at low temperature, compositions containing at least one of the compounds and liquid crystal display devices containing such a liquid crystal compositions are disclosed.
    Type: Grant
    Filed: June 2, 1999
    Date of Patent: February 17, 2004
    Assignee: Chisso Corporation
    Inventors: Takashi Kato, Tomoyuki Kondo, Henry Bernhardt, Shuichi Matsui, Hiroyuki Takeuchi, Yasuhiro Kubo, Fusayuki Takeshita, Etsuo Nakagawa
  • Patent number: 6685995
    Abstract: Liquid crystalline compounds suitable for driving at a low voltage and at a wide temperature range, and suitable for high speed response, liquid crystal compositions comprising the compound, and liquid crystal display devices comprising the liquid crystal composition. The crystalline compounds are ester compounds expressed by the general formula (1) wherein R1 represents e.g. a hydrogen atom; A1 to A5 each independently represent e.g. 1,4-cyclohexylene, 1,4-phenylene, 1-cyclohexene-1,4-diyl, 3-cyclohexene-1,4-diyl, 1-sila-1,4-cyclohexylene, or 4-sila-1,4-cyclohexylene; bonding groups Za to Zd each independently represent e.g. a single bond, —CH2—, —O—, —C≡C—, or an alkylene group or alkenylene group having 2 to 4 carbon; bonding group Ze represents e.g.
    Type: Grant
    Filed: July 7, 2000
    Date of Patent: February 3, 2004
    Assignee: Chisso Corporation
    Inventors: Yasuhiro Haseba, Shuichi Matsui, Hiroyuki Takeuchi, Yoshitaka Yagi, Fusayuki Takeshita, Etsuo Nakagawa
  • Patent number: 6673934
    Abstract: Primary intermediates for hair coloring compositions for oxidative dyeing of hair are compounds of the formula (1): wherein R is hydrogen, hydroxy, nitro, amino, halogen, C1 to C5 alkyl or haloalkyl, C1 to C5 alkoxy or cyclic alkoxy, C1 to C5 hydroxyalkyl and C1 to C5 hydroxyalkoxy; Ar is an aromatic group, preferably an aromatic group selected from a furanyl, thienyl, pyridinyl, phenyl, 2,3-dihydro-benzo[1,4]dioxin-5 or -6-yl or benzo[1,3]dioxol-4 or -5-yl group; and y=1 to 3.
    Type: Grant
    Filed: January 18, 2002
    Date of Patent: January 6, 2004
    Assignee: The Procter & Gamble Company
    Inventors: Mu-Ill Lim, Yuh-Guo Pan
  • Publication number: 20030213935
    Abstract: Liquid-crystalline compounds of the formula I 1
    Type: Application
    Filed: September 30, 2002
    Publication date: November 20, 2003
    Applicant: Merck Patent GmbH
    Inventors: Michael Heckmeier, Peer Kirsch, Joachim Krause, Alexander Hahn, Andreas Ruhl
  • Patent number: 6649227
    Abstract: Provided are liquid crystalline compounds having a wide liquid crystal phase temperature range, low viscosity, a large elastic constant ratio K33/K11 and excellent solubility at low temperature, a liquid crystal composition using the same and a liquid crystal display.
    Type: Grant
    Filed: July 6, 2001
    Date of Patent: November 18, 2003
    Assignees: Chisso Corporation, Chisso Petrochemical Corporation
    Inventors: Takashi Kato, Shuichi Matsui, Hiroyuki Takeuchi, Yasuhiro Kubo, Etsuo Nakagawa