Polycyclo Ring System Containing Anthracene Configured Ring System Having At Least One Double Bond Between Ring Members And Having Oxygen Single Bonded Or Any Atom Double Bonded Directly At The 9- And 10-positions (e.g., Anthraquinones, Etc.) Patents (Class 552/208)
  • Patent number: 10031417
    Abstract: A compound represented by Chemical Formula 1, a colorant including the compound, a photosensitive resin composition including the colorant, and a color filter manufactured using the photosensitive resin composition (in Chemical Formula 1, each substituent is the same as defined in the detailed description),
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: July 24, 2018
    Assignee: Samsung SDI Co., Ltd.
    Inventors: Hyeongmook Kim, Kyuyoung Kim, Young Lee, Myoungyoup Shin, Seungjib Choi
  • Patent number: 8895725
    Abstract: Use of 9,10-anthraquinone compounds of formula (I) or pharmaceutical salts thereof or plant extracts containing said compounds in the preparation of anti-HCV medicaments is disclosed, in which Y1 are Y2 are independently hydrogen, hydroxyl or groups of formula (II); and R1, R2, R3, R4, R5 and R6 are independently hydrogen, hydroxyl, carboxyl, cyano group, nitro group, groups of formula (III) or groups selected from those substituted or unsubstituted groups: amino, C1-C6 aliphatic hydrocarbon, C3-C7 cyclic aliphatic hydrocarbon, C1-C6 alkoxy, C2-C7 carbalkoxy, C1-C4 acyloxy, C6-C20 aryl, or 5 to 7 members heterocyclic or benzoheterocyclic thereof; or R5 and R6 form the group of formula (IV). The compounds of present invention are cheap, safe and effective because that they mostly come from traditional Chinese medicines and have better anti-HCV effects and lighter side effects.
    Type: Grant
    Filed: November 23, 2009
    Date of Patent: November 25, 2014
    Assignees: Shanghai Institute of Pharmaceutical Industry, Institute Pasteur of Shanghai, Chinese Academy of Sciences
    Inventors: Shuguang Wang, Jin Zhong, Deyun Kong, Jue Hu, Bo Li, Wen Gao, Chunyan Gai, Changlong Zhuang, Haitao Mao
  • Patent number: 8846758
    Abstract: Methods for treating abnormal glycosylated hemoglobin (HbA1c) levels in a patient in need thereof, wherein the provided methods comprise administering to a patient in need a therapeutically effective amount of an Interleukin-1? modulator. Also, the invention provides compositions comprising at least one lipid modifying agent and an IL-1? modulator.
    Type: Grant
    Filed: July 19, 2012
    Date of Patent: September 30, 2014
    Assignee: TWi Biotechnology, Inc.
    Inventors: Mannching Sherry Ku, Chih-Kuang Chen, Wei-Shu Lu, Chih-Ming Chen, I-Yin Lin
  • Patent number: 8637506
    Abstract: The mechanism by which the high bone mass (HBM) mutation (G171V) of the Wnt coreceptor LRP5 regulates the canonical Wnt signaling was investigated. The mutation was previously shown to reduce Dkk protein-1-mediated antagonism, suggesting that the first YWTD repeat domain where G171 is located may be responsible for Dkk protein-mediated antagonism. However, we found that the third YWTD repeat, but not the first repeat domain, is required for DKK1-mediated antagonism. Instead, we found that the G171V mutation disrupted the interaction of LRP5 with Mesd, a chaperon protein for LRP5/6 that is required for the coreceptors' transport to cell surfaces, resulting in less LRP5 molecules on the cell surface. Although the reduction in the level of cell surface LRP5 molecules led to a reduction in Wnt signaling in a paracrine paradigm, the mutation did not appear to affect the activity of coexpressed Wnt in an autocrine paradigm.
    Type: Grant
    Filed: May 19, 2004
    Date of Patent: January 28, 2014
    Assignees: Enzo Biochem, Inc., University of Connecticut, St. Jude's Childrens Hospital
    Inventors: Dianqing Wu, Yazhou Zhang, Peng Liu, Xiaofeng Li, Jie Zhang, Jufang Shan, Dean Engelhardt
  • Publication number: 20130225517
    Abstract: The invention provides compounds of formula I: or salts thereof as described herein. The invention also provides pharmaceutical compositions comprising a compound of formula I and therapeutic methods for treating cancer.
    Type: Application
    Filed: February 22, 2013
    Publication date: August 29, 2013
    Applicant: University of Iowa Research Foundation
    Inventor: University of Iowa Research Foundation
  • Patent number: 8492569
    Abstract: A (meth)acrylate ester includes a (meth)acrylate moiety having an ester oxygen, an anthraquinone moiety having a transmittance spectrum producing blue light, and a linking group covalently bound to the ester oxygen and to a ring of the anthraquinone moiety, the linking group including, as a first component: phenyl, naphthyl, a linear alkyl group having from 1 to about 6 carbons, a branched alkyl group having from 3 to about 6 carbons, a cycloalkyl group having from about 3 to about 20 carbons, or a substituted aromatic group.
    Type: Grant
    Filed: December 18, 2009
    Date of Patent: July 23, 2013
    Assignee: Cheil Industries, Inc.
    Inventors: Shahrokh Motallebi, Sina Maghsoodi
  • Patent number: 8461155
    Abstract: The loss of the SOST gene product sclerostin leads to sclerosteosis characterized by high bone mass (HBM). In this report, we found that sclerostin could antagonize canonical Wnt signaling in human embryonic kidney A293 cells and mouse osteoblastic MC3T3 cells. This sclerostin-mediated antagonism could be reversed by over-expression of Wnt coreceptor LRP5. In addition, we found that sclerostin bound to LRP5 as well as LRP6 and identified the first two YWTD-EGF repeat domains of LRP5 as being responsible for the binding. Although these two repeat domains are required for transducing canonical Wnt signals, canonical Wnt did not appear to compete with sclerostin for binding to LRP5. Examination of the expression of sclerostin and Wnt7b, an autocrine canonical Wnt, during primary calvarial osteoblast differentiation revealed that sclerostin is expressed at the late stages of osteoblast differentiation coinciding with the expression of osteogenic marker osteocalcin and trailing after the expression of Wnt7b.
    Type: Grant
    Filed: March 18, 2005
    Date of Patent: June 11, 2013
    Assignee: University of Connecticut
    Inventors: Dianqing (Dan) Wu, Xiaofeng Li
  • Patent number: 8350089
    Abstract: The present invention discloses a process for the production of 2-methyl-1,4-naphthoquinone and its bisulfite adducts, comprising the following steps: a) oxidizing 2-methyl-naphthalene (2-MNA) to achieve an organic phase containing 2-methyl-naphthoquinone (2-MNQ) and 6-methyl-naphthoquinone (6-MNQ); b) subjecting said organic phase to treatment with an aqueous solution of a bisulfite salt to extract preferentially the 6-MNQ isomer from the organic phase; c) separating said organic phase from the aqueous phase; d) subjecting the organic phase of process step c) to a second bisulfidation step with an aqueous solution of a bisulfite salt, resulting in an organic phase containing 2-MNA and trace amounts of 2-MNQ and an aqueous phase containing 2-MSB and trace amounts of 6-MSB; e) optionally removing interfering bisulfite ions from the aqueous phase of process step c); f) raising the pH of the aqueous phase from step c) or e) to higher than 8.
    Type: Grant
    Filed: January 11, 2011
    Date of Patent: January 8, 2013
    Assignee: Lonza Ltd.
    Inventors: Kamyab Amouzegar, Behzad Mahdavi, Charles Didier, Alexander Lieb, Mathieu Langevin
  • Patent number: 8323745
    Abstract: An application liquid capable of forming a dense silica-based coating film even when embedded into a fine groove, and a method for formation of a silica-based coating film using the application liquid are provided. An application liquid is used including (A) a siloxane polymer, and (B) a base generator represented by the following general formula (I): wherein, R1 and R2 are a hydrocarbon group having 1 to 5 carbon atoms and which may be the same or different; or one of R1 and R2 is a hydrogen atom and the other is a hydrocarbon group having 1 to 5 carbon atoms; when R1 and R2 are both a hydrocarbon group, these may bind to one another to form a ring structure; R3 is a linking group; and R4 is a condensed ring.
    Type: Grant
    Filed: March 26, 2010
    Date of Patent: December 4, 2012
    Assignee: Tokyo Ohka Kogyo Co., Ltd.
    Inventors: Tokonori Yamadaya, Kiyoshi Ishikawa, Atsushi Sawano
  • Patent number: 8318048
    Abstract: The invention relates to a process of preparing substituted pentacenes, to novel pentacenes prepared by this process, to the use of the novel pentacenes as semiconductors or charge transport materials in optical, electrooptical or electronic devices including field effect transistors (FETs), electroluminescent, photovoltaic and sensor devices, and to FETs and other semiconducting components or materials comprising the novel pentacenes.
    Type: Grant
    Filed: March 28, 2008
    Date of Patent: November 27, 2012
    Assignee: Merck Patent GmbH
    Inventors: Steven Tierney, Martin Heeney, Clare Bailey, Weimin Zhang
  • Publication number: 20120090995
    Abstract: Devices for detecting an analyte comprising a redox active analyte sensitive material on a working electrode and computer assisted signal acquisition and processing.
    Type: Application
    Filed: March 25, 2010
    Publication date: April 19, 2012
    Applicant: SENOVA SYSTEMS, INC.
    Inventors: Lee Leonard, Joseph A. Duimstra, Eric Lee, Mark Micklatcher, Victor Simonyi, Gregory G Wildgoose, Joseph I. Keto, Anton Seidl
  • Patent number: 8124637
    Abstract: A series of novel anthra[1,2-d]imidazole-6,11-dione derivatives, and the preparation method and application of said derivatives, wherein said application includes a pharmaceutical composition containing said derivatives for treating cancer, and said application involves effects of said derivatives for inhibiting telomerase activity, inhibiting the growth of cancer cell, treating cancer and the like.
    Type: Grant
    Filed: February 25, 2010
    Date of Patent: February 28, 2012
    Assignee: National Defense Medical Center
    Inventor: Hsu-Shan Huang
  • Patent number: 8118881
    Abstract: A hair dye containing a compound represented by the following general formula (I): wherein R1 and R2 each independently represent a hydrogen atom or a straight chain or branched alkyl group having 1 to 5 carbon atoms, and An? represents an inorganic anion, an organic anion, or a complex salt anion, respectively.
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: February 21, 2012
    Assignee: Hodogaya Chemical Co., Ltd.
    Inventors: Masahiko Yamaguchi, Shiro Irisa, Eiji Takahashi, Katsumasa Kikkawa
  • Patent number: 8114979
    Abstract: The invention provides novel anthraquinone compositions that are useful as broad-spectrum quenchers of fluorescence and provides methods for making and using them. The anthraquinone quenchers can be conjugated to a variety of biologically relevant compounds, including lipids, nucleic acids, polypeptides, and more specifically antigens, steroids, vitamins, drugs, haptens, metabolites, toxins, environmental pollutants, amino acids, peptides, proteins, nucleotides, oligonucleotides, polynucleotides, carbohydrates, and their analogs. The invention also provides kits comprising, in one or more containers, at least one anthraquinone quencher dye composition of the present invention, and instructions for using that composition.
    Type: Grant
    Filed: August 10, 2010
    Date of Patent: February 14, 2012
    Assignee: Integrated DNA Technologies, Inc.
    Inventors: Andrei Laikhter, Mark Aaron Behlke, Yawfui Yong, Scott Rose, Lingyan Huang
  • Publication number: 20110239903
    Abstract: A method of producing a modified pigment by sulfonating a pigment and subsequently oxidizing the pigment. The modified pigment may have sulfonic acid and carboxyl surface modifying groups attached to the surface of the pigment. Charge balancing counterions such as alkali metals, alkaline earth metals and NR1R2R3H+, where R1, R2 and R3 are independently H or C1-C5 alkyl groups, may be associated with the surface modifying groups. The modified pigment is combined with water to produce a dispersion that can be used in such applications as coatings, paints, papers, adhesives, latexes, toners, textiles, fibers, plastics and inks.
    Type: Application
    Filed: March 8, 2011
    Publication date: October 6, 2011
    Inventors: Puthalath K. Sujeeth, Mark Ulrich, Gabe Srouji, John Kane, Daniel A. Ouellette
  • Publication number: 20110172448
    Abstract: A cost effective process is presented for carrying out catalytic, in particular also exothermic, endothermic or autothermal reactions with optimum yield and selectivity. The system used is a wall-flow monolith which forces a flow from the inlet channel through the porous wall into the outlet channel by reciprocal closure of the gas channels. This is operated such that mass transfer and heat transport are determined virtually exclusively by convection, and diffusion-related thermal conduction phenomena can be neglected.
    Type: Application
    Filed: June 24, 2009
    Publication date: July 14, 2011
    Inventors: Martin Votsmeier, Susanne Ungermann, Juergen Gieshoff, Thomas Kreuzer
  • Patent number: 7910754
    Abstract: A compound of the formula wherein R1, R2, R3, R4, R5, R6, R?, R?, Y, CA+, and A? each, independently of the others are as defined herein.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: March 22, 2011
    Assignee: Xerox Corporation
    Inventor: Jeffrey H. Banning
  • Patent number: 7901594
    Abstract: The present invention relates to polyacene derivatives represented by general formula (I) below: (wherein R1 to R10, etc. each represents hydrogen atom, hydrocarbon group, or an alkoxy group; A1 and A2 are hydrogen atom, a halogen atom, a hydrocarbon group, an alkoxy group, cyano group, etc.; n is an integer of not less than 1; R6 and R7 may be linked to each other to form a ring); and a process for preparing the polyacene derivatives from polyhydro compounds as well as electrically conductive materials comprising the polyacene derivatives. According to the process for preparing the polyacene derivatives of the present invention, optional substituents can be introduced into any carbon atoms of the polyacene, and the number of aromatic rings can be increased.
    Type: Grant
    Filed: February 28, 2001
    Date of Patent: March 8, 2011
    Assignee: Japan Science and Technology Corporation
    Inventor: Tamotsu Takahasi
  • Patent number: 7884356
    Abstract: A donor substrate for forming a nano conductive film includes a base substrate and a transferring layer that is disposed on the base substrate. The transferring layer includes nano conductive particles and an organic semiconductor. A method of patterning a nano conductive film is provided, wherein a donor substrate in which nano conductive particles are dispersed by employing an organic semiconductor having low molecular weight as a binder is prepared, and nano conductive particles are patterned on a receptor substrate by employing the donor substrate. The method can be used to prepare patterns of various devices including a display device such as an OLED and an OTFT. Such a device can be prepared simply and economically by preparing a device comprising nano conductive particles and an organic semiconductor in wet basis even without deposition.
    Type: Grant
    Filed: March 31, 2006
    Date of Patent: February 8, 2011
    Assignee: Samsung Mobile Display Co., Ltd.
    Inventors: Jong-Jin Park, Myeong-Suk Kim, Tae-Yong Noh, Sung-Hun Lee, Sang-Yoon Lee, Eun-Jeong Jeong
  • Patent number: 7803536
    Abstract: The invention provides novel anthraquinone compositions that are useful as broad-spectrum quenchers of fluorescence and provides methods for making and using them. The anthraquinone quenchers can be conjugated to a variety of biologically relevant compounds, including lipids, nucleic acids, polypeptides, and more specifically antigens, steroids, vitamins, drugs, haptens, metabolites, toxins, environmental pollutants, amino acids, peptides, proteins, nucleotides, oligonucleotides, polynucleotides, carbohydrates, and their analogs. The invention also provides kits comprising, in one or more containers, at least one anthraquinone quencher dye composition of the present invention, and instructions for using that composition.
    Type: Grant
    Filed: September 19, 2003
    Date of Patent: September 28, 2010
    Assignee: Integrated DNA Technologies, Inc.
    Inventors: Mark Aaron Behlke, Lingyan Huang, Andrei Laikhter, Yawfui Yong, Scott Rose
  • Publication number: 20090076206
    Abstract: An agricultural article made of a composition containing (a) an organic polymer, and (b) an additive mixture comprising the components (b-0) a photosensitizer, (b-I) an organic salt of a transition metal, and optionally (b-II) an inorganic peroxide or inorganic superoxide.
    Type: Application
    Filed: March 27, 2006
    Publication date: March 19, 2009
    Inventors: Stefano Gardi, Piero Piccinelli, Massimiliano Sala, Wiebke Wunderlich-Wippert, Michela Bonora
  • Patent number: 7485737
    Abstract: A compound of the formula wherein R1, R2, R3, R4, R5, R6, R?, R?, Y, CA+, and A? each, independently of the others are as defined herein.
    Type: Grant
    Filed: February 6, 2007
    Date of Patent: February 3, 2009
    Assignee: Xerox Corporation
    Inventor: Jeffrey H. Banning
  • Patent number: 7481847
    Abstract: The present disclosure relates to a composition for dyeing human keratin fibers, comprising at least one cationic direct dye of formula (I), described herein, and at least one cosmetic agent chosen from thickening agents and surfactants. Also disclosed herein is a dyeing process comprising applying a composition of the present disclosure to keratin fibers, in the presence or absence of an oxidizing agent. Further disclosed herein is a multi-compartment device comprising at least one first compartment containing a dye composition of the present disclosure and at least one second compartment containing at least one oxidizing composition.
    Type: Grant
    Filed: March 27, 2007
    Date of Patent: January 27, 2009
    Assignee: L'Oreal S.A.
    Inventors: Alain Lagrange, Leïla Hercouet
  • Patent number: 7453004
    Abstract: A process for preparing aloe-emodin from aloin by oxidizing aloin by treatment with an oxygen-containing gas in the presence of an acid. The aloe-emodin may be used for the production of rhein and diacerein by oxidizing aloe-emodin by treatment with a chromium-free oxidizing medium to obtain rhein and purifying the rhein obtained. The rhein may be acetylated to obtain diacerein.
    Type: Grant
    Filed: November 11, 2005
    Date of Patent: November 18, 2008
    Assignee: Laboratoire Medidom S.A.
    Inventors: Stefano Carlino, Guido Di Napoli
  • Patent number: 7214713
    Abstract: A food supplement having prophylactic and-cancer effects, wherein the supplement comprises 20 to 99.99% by weight of a product of biosynthesis by the productive microorganism Penicillium oxalicum var. Armeniaca CCM 8242, obtained by fermentation of a nutrient broth containing carbohydrates and ammonia nitrogen, and 0.01 to 8?% by weight of a physiologically inert carrier, and optionally auxiliary additives.
    Type: Grant
    Filed: July 23, 2001
    Date of Patent: May 8, 2007
    Inventor: Eduard Sardaryan
  • Patent number: 7160335
    Abstract: The present invention relates to a compound of formula I wherein R1 and R3 are each independently of the other —NHR5, NHSO2R5, —NHCOR5, —OR6 or —SR7, R2 and R4 are each independently of the other —OR6 or —SR7, with the proviso that not all of the substituents R1 to R4 are —SR7, R5 is hydrogen, alkyl, aryl, aralkyl or a group of formula —(CnH2nX)m—H wherein X is —O—, —S—, —SO2—, —NH—, —NR8—, —CONH— or —CONR8— and R8 is alkyl or aryl, n is a number from 2 to 6 and m is a number from 1 to 10, R6 is aryl or heteroaryl and R7 is alkyl, aryl, heteroaryl or a group of formula —(CnH2nX)m—H wherein X is —O—, —S—, —SO2—, —NH—, —NR8—, CONH— or —CONR8— and R8 is alkyl or aryl, to a process for the preparation thereof and to the use thereof in a method of producing mass-coloured plastics or polymeric colour particles.
    Type: Grant
    Filed: March 13, 2003
    Date of Patent: January 9, 2007
    Assignee: Ciba Specialty Chemicals Corporation
    Inventors: Urs Lauk, Patric Nowack, Alfons Arquint
  • Patent number: 7132403
    Abstract: Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the formula: wherein R1, R2, R3, and R4 are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combination thereof, R is a group containing 1 to 12 carbons such as methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, or combination thereof, and the halogen is I, F, Br, or Cl.
    Type: Grant
    Filed: January 20, 2004
    Date of Patent: November 7, 2006
    Assignees: Board of Trustees of Michigan State University, Regents of the University of California
    Inventors: Robert H. Cichewicz, Muraleedharan G. Nair, James H. McKerrow
  • Patent number: 7056346
    Abstract: The present invention relates to a composition comprising, in a cosmetically acceptable support suitable for dyeing the hair, at least one direct dye and at least one crosslinked polymer containing acrylic residue units of the structure in which R1 denotes H, CH3 or C2H5, and C10–C30 alkyl acrylate residue units, wherein the composition is a direct dyeing composition for the hair, and wherein said at least one direct dye is an anthraquinone or azo dye which is acidic or cationic.
    Type: Grant
    Filed: September 18, 2000
    Date of Patent: June 6, 2006
    Assignee: L'Oreal S.A.
    Inventor: Mireille Maubru
  • Patent number: 6914114
    Abstract: An absorbing ether-like compound including a siliconethoxy, silicondiethoxy, or silicontriethoxy species attached to a naphthalene or anthracene chromophore via an oxygen linkage is used as an organic light-absorbing compound. The absorbing ether-like compound is incorporated into spin-on glass materials to provide anti-reflective coating materials for deep ultraviolet photolithography. A method of synthesizing the light-absorbing ether compounds is based on the reaction of an alcohol-substituted chromophore with an acetoxysilicon compound in the presence of alcohol. A method of making absorbing spin-on-glass materials including the absorbing ether-like compounds is also provided.
    Type: Grant
    Filed: April 30, 2003
    Date of Patent: July 5, 2005
    Assignee: Honeywell International Inc.
    Inventors: Teresa Baldwin, Mary Richey, James S. Drage, Hui-Jung Wu, Richard Spear
  • Patent number: 6903076
    Abstract: Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the formula: wherein R1, R2, R3, and R4 are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combination thereof, R is a group containing 1 to 12 carbons such as methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, or combination thereof, and the halogen is I, F, Br, or Cl.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: June 7, 2005
    Assignees: Board of Trustees of Michigan State University, The Regents of the University of California
    Inventors: Robert H. Cichewicz, Muraleedharan G. Nair, James H. McKerrow
  • Patent number: 6875746
    Abstract: Anthraquinones are described which have anticancer or antitumor activity and which are useful for inhibiting cancer cells and cells comprising tumors in vitro or in vivo. Preferably, the anthraquinones have the chemical formula: wherein R1 is selected from the group consisting of hydrogen, alkyl, and substituted alkyl; R2 is a group containing 1-12 carbons selected from the group consisting of alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate and combinations thereof; and R3 is a group containing 1 to 12 carbons selected from the group consisting of methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, and combinations thereof.
    Type: Grant
    Filed: January 31, 2003
    Date of Patent: April 5, 2005
    Assignee: Board of Trustees of Michigan State University
    Inventors: Muraleedharan G. Nair, Robert H. Cichewicz, Navindra P. Seeram, Yanjun Zhang
  • Patent number: 6861541
    Abstract: Disclosed herein is a method for producing a 1-[4-(biphenyl-4-carbonyl)]phenylaminonthraquinone colorant composition where the method comprises: reacting 4-halobenzoic acid with about 1 mole to about 4 moles of a halogenating agent per mole of said 4-halobenzoic acid to form a 4-halobenzoyl halide composition; reacting in the presence of a first catalyst composition, said 4-halobenzoyl halide composition with biphenyl, in a solvent, to form a 1-[4-(biphenyl-4-carbonyl)]halobenzene composition, and reacting in the presence of a second catalyst composition and an acid scavenger, said 1-[4-(biphenyl-4-carbonyl)]phenylaminonthraquinone with a 1-aminoanthraquinone, in a reaction medium comprising a dipolar aprotic solvent, to form said 1-[4-(biphenyl-4-carbonyl)]phenylaminoanthraquinone colorant composition.
    Type: Grant
    Filed: January 15, 2004
    Date of Patent: March 1, 2005
    Assignee: General Electric Company
    Inventors: Arun Nandkishor Dixit, Adil Minoo Dhalla
  • Patent number: 6838443
    Abstract: Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the formula: wherein R1, R2, R3, and R4 are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combination thereof, R is a group containing 1 to 12 carbons such as methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, or combination thereof, and the halogen is I, F, Br, or Cl.
    Type: Grant
    Filed: November 26, 2003
    Date of Patent: January 4, 2005
    Assignees: Board of Trustees of Michigan State University, The Regents of the University of California, The United States of America as represented by the Department of Veterans Affairs
    Inventors: Robert H. Cichewicz, Muraleedharan G. Nair, James H. McKerrow
  • Patent number: 6835211
    Abstract: The invention relates to coloring and toning agents for keratinous fibers, in particular human hair, comprising at least one hydroxyanthraquinone derivative of formula (I), as a direct dye, in a cosmetically acceptable vehicle, where R=a group of formula (II), where R1 to R4=independently, H; OH; C1 to C4 alkoxy; C1 to C4 alkyl; C1 to C4 fluoroalkyl; carboxy; NO2; halogen; a group of formula SR5, where R5=H or C1 in C4 alkyl; a group of formula PhCH2—COOR6, where R6=H, C1 to C4 alkyl or a physiologically acceptable cation or, any two neighboring groups of R1 to R4 form a methylenedioxy rin and X=halogen. The inventive agents permit hair coloring with outstanding fastness.
    Type: Grant
    Filed: August 15, 2002
    Date of Patent: December 28, 2004
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: David Rose, Bernd Meinigke, Horst Hoeffkes
  • Publication number: 20040232382
    Abstract: A liquid crystal composition comprising at least one liquid crystal compound and at least one anthraquinone compound represented by formula (1) below: Formula (1) (wherein R2 to R8 each independently represents a hydrogen or substituent; Het is a sulfur or oxygen; B1 and B2 each independently represents an optionally substituted arylene, heteroarylene, cycloalkan-diyl or cycloalken-diyl; Q1 is a bivalent linking group; C1 is an optionally substituted alkyl, cycloalkyl, alkoxy, alkokycarbonyl or acyloxy; p, q and r each represents a number from 0 to 5 and n is a number from 1 to 3 satisfying 3≦(p+r)×n≦10; when plural {(B1)p-(Q1)q-(B2)r} are present, these may be the same or different) was disclosed.
    Type: Application
    Filed: July 12, 2004
    Publication date: November 25, 2004
    Inventors: Hisashi Okamura, Takashi Katoh
  • Patent number: 6800615
    Abstract: Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the formula: wherein R1, R2, R3, and R4 are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combination thereof, R is a group containing 1 to 12 carbons such as methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, or combination thereof, and the halogen is I, F, Br, or Cl.
    Type: Grant
    Filed: December 12, 2002
    Date of Patent: October 5, 2004
    Assignees: Board of Trustees of Michigan State University, The Regent of the University of California, The United States of America as represented by the Department of Veterans Affairs
    Inventors: Robert H. Cichewicz, Muraleedharan G. Nair, James H. McKerrow
  • Publication number: 20040087663
    Abstract: This invention provides various biquinone and trimeric quinone derivatives. The invention also provides a method for synthesis of a multi-quinone compound including reacting a hydroxyquinone anion with a first quinone possessing a first directing group at a C-2 of the first quinone and a second directing group at a C-3 of the first quinone and obtaining a biquinone having one of the first and second directing groups at a C-3 of a first quinone monomer and a hydroxyl group at a C-3′ of a second quinone monomer. The biquinone can be further reacted to obtain various biquinone derivatives or with a second hydroxyquinone anion to obtain trimeric quinone derivatives, including trimeric naphthoquinone derivatives. The biquinones and trimeric quinones of this invention demonstrate antiviral activity and can be used to treat viral infections, particularly HIV infections.
    Type: Application
    Filed: November 6, 2002
    Publication date: May 6, 2004
    Inventors: Kenneth William Stagliano, Ashkan Emadi
  • Patent number: 6673257
    Abstract: A thermal cutoff member and compositions used to manufacture such members are described herein as including at least two organic compounds which, when sufficiently combined, give rise to a component which has a lower melt transition temperature than the initial organic compounds prior to combining the same. The thermal cutoff member is generally utilized in a thermal cutoff construction having an electrical switching unit that changes its operating condition when the member therein melts by being heated to a certain temperature for the particular material that forms the member being utilized.
    Type: Grant
    Filed: September 12, 2000
    Date of Patent: January 6, 2004
    Assignee: Therm-O-Disc, Incorporated
    Inventor: Christine M. Hudson
  • Patent number: 6669994
    Abstract: A method of forming a polymer layer on a support surface by the use of a coating agent and polymerizable compounds. The coating agent provides photoreactive groups adapted to attach the agent to the surface, as well as photoreactive groups adapted to remain unattached to the surface, and thus serve as photoinitiators for the activation of polymerizable compounds in order to form a polymer layer thereon. Also provided are coating agents, per se, as well as a method of using such agents and the resultant surfaces and devices fabricated therefrom.
    Type: Grant
    Filed: April 23, 2001
    Date of Patent: December 30, 2003
    Assignee: SurModics, Inc.
    Inventors: Dale G. Swan, Richard A. Amos, Terrence P. Everson, Stephen J. Chudzik, Ralph A. Chappa, Sean M. Stucke, Peter H. Duquette
  • Patent number: 6635350
    Abstract: Red colorants comprising a chromophore having at least one poly(oxyalkylene) chain attached to the 1-position, as well as at least one poly(oxyalkylene) chain attached to either the 5-position or the 8-position of an anthraquinone backbone are provided. Such colorants exhibit excellent base stability, effective colorations, excellent low extraction rates, and high lightfastness levels, particularly when incorporated within certain media and/or on the surface of certain substrates, particularly polyesters. The poly(oxyalkylene) chains also increase the solubility in different solvents or resins thereby permitting the introduction of such excellent coloring chromophores within diverse media and/or diverse substrates as well as provides a liquid colorant which facilitates handling. Compositions and articles comprising such colorants are provided as well as methods for producing such inventive colorants are also provided.
    Type: Grant
    Filed: October 16, 2001
    Date of Patent: October 21, 2003
    Assignee: Milliken & Company
    Inventors: Daniel M. Connor, John W. Miley, Jr.
  • Publication number: 20030181741
    Abstract: The invention relates to a method of regenerating hydrogenated and/or oxygenated alkyl anthraquinones and/or alkyl anthrahydroquinones to alkyl anthraquinones and/or alkyl anthrahydroquinones, wherein the reaction is carried out in the presence of a catalyst under electromagnetic irradiation.
    Type: Application
    Filed: January 22, 2003
    Publication date: September 25, 2003
    Inventors: Reijo Aksela, Juhani Paloniemi
  • Patent number: 6620858
    Abstract: Disclosed are thermally-stable, colored, photopolymerizable compounds containing a vinyl group which are capable of being copolymerized with reactive vinyl monomers to produce colored compositions such as polyacrylates, polymethacrylates, polystyrene, etc. The compounds exhibit good thermal stability, fastness (stability) to UV-light, good solubility in the reactive monomers and good color strength.
    Type: Grant
    Filed: August 1, 2001
    Date of Patent: September 16, 2003
    Assignee: Eastman Chemical Company
    Inventors: Michael John Cyr, Max Allen Weaver, Gerry Foust Rhodes, Jason Clay Pearson, Phillip Michael Cook, Jos Simon De Wit, Larry Keith Johnson
  • Patent number: 6605362
    Abstract: An absorbing ether-like compound including a siliconethoxy, silicondiethoxy, or silicontriethoxy species attached to a naphthalene or anthracene chromophore via an oxygen linkage is used as an organic light-absorbing compound. The absorbing ether-like compound is incorporated into spin-on glass materials to provide anti-reflective coating materials for deep ultraviolet photolithography. A method of synthesizing the light-absorbing ether compounds is based on the reaction of an alcohol-substituted chromophore with an acetoxysilicon compound in the presence of alcohol. A method of making absorbing spin-on-glass materials including the absorbing ether-like compounds is also provided.
    Type: Grant
    Filed: November 5, 2001
    Date of Patent: August 12, 2003
    Assignee: Honeywell International Inc.
    Inventors: Teresa Baldwin, Mary Richey, James S. Drage, Hui-Jung Wu, Richard Spear
  • Patent number: 6596884
    Abstract: A method for synthesizing hydrogen peroxide comprises the steps of: synthesizing an analog of anthraquinone that is miscible or soluble in carbon dioxide; reacting the analog of anthraquinone with hydrogen in carbon dioxide to produce a corresponding analog of tetrahydroquinone; and reacting the analog of tetrahydroquinone with oxygen to produce the hydrogen peroxide and regenerate the analog of anthraquinone. A chemical compound having the formula: wherein R1, R2, R3, R4, R5, R6, R7, and R8 are independently, the same or different, H, RC, or RSRC, wherein RS is a spacer group and RC is a fluoroalkyl group, a fluoroether group, a silicone group, an alkylene oxide group, a fluorinated acrylate group, or a phosphazine group, and wherein at least one of R1, R2, R3, R4, R5, R6, R7, and R8 is not H.
    Type: Grant
    Filed: November 30, 2001
    Date of Patent: July 22, 2003
    Assignee: University of Pittsburgh
    Inventors: Eric J. Beckman, Dan Hâncu
  • Patent number: 6596036
    Abstract: The present invention relates to a method for the production of a dye preparation from madder root, comprising extraction of madder root in water at a temperature below 70-75° C., preferably below 65° C., while providing oxygen to the reaction mixture of madder root in water to obtain the dye preparation and to the dye preparation thus obtained.
    Type: Grant
    Filed: September 25, 2001
    Date of Patent: July 22, 2003
    Assignee: Coöperatie Rubia U.A.
    Inventors: Goverdina Christina Helena Derksen, Teris André Van Beek, Aede De Groot, Anthony Capelle
  • Publication number: 20030134924
    Abstract: Disclosed are thermally-stable, red, anthraquinone colorants which contain one or more ethylenically-unsaturated, photopolymerizable radicals and which may be copolymerized with ethylenically-unsaturated monomers to produce colored compositions such as colored acrylic polymers, colored polystyrenes, and similar colored polymeric materials derived from other ethylenically-unsaturated monomers. The compounds possess good stability to ultraviolet light, good solubility in vinyl monomers, good color strength and thermal stability. Also disclosed are acrylic polymeric materials, i.e., polymers derived from acrylic acid esters, methacrylic acid esters and/or other copolymerizable vinyl compounds, having copolymerized therein one or more of the colorant compounds of the present invention.
    Type: Application
    Filed: November 13, 2001
    Publication date: July 17, 2003
    Inventors: Michael John Cyr, Max Allen Weaver, Gerry Foust Rhodes, Jason Clay Pearson, Jean Carroll Fleischer
  • Patent number: 6579994
    Abstract: The present invention describes a process for the preparation of 2-Methyl-1,4-naphthoquinone by oxidizing 2-methylnaphthalene with hydrogen peroxide in the presence of acetic acid.
    Type: Grant
    Filed: March 29, 2001
    Date of Patent: June 17, 2003
    Assignee: Council of Scientific and Industrial Research
    Inventors: Narayanan Sankarasubbier, Katravulapalli V.V.S.B.S. Murthy, Kongara Madhusudan Reddy, Premchendar Nandhikonda
  • Publication number: 20030097010
    Abstract: A process for preparing substituted pentacene compounds comprises the step of cyclizing substituted bis(benzyl)phthalic acids using an acid composition comprising trifluoromethanesulfonic acid, the substituted bis(benzyl)phthalic acids being represented by the following general formulas: 1
    Type: Application
    Filed: September 27, 2001
    Publication date: May 22, 2003
    Inventors: Dennis E. Vogel, Kim M. Vogel
  • Patent number: 6562121
    Abstract: Organic pigments are conditioned by introducing a liquid prepigment suspension into a miniaturized continuous reactor and thermally treating therein.
    Type: Grant
    Filed: June 27, 2001
    Date of Patent: May 13, 2003
    Assignee: Clariant Finance (BVI) Limited
    Inventors: Uwe Nickel, Klaus Kund, Erwin Dietz, Joachim Weber, Olaf Schupp
  • Publication number: 20020193615
    Abstract: The invention relates to a method of hydrogenating alkyl anthraquinones and/or alkyl hydroanthraquinones to alkyl anthrahydroquinones and/or alkyl hydroanthrahydroquinones, wherein the reaction is carried out in the presence of a catalyst under electromagnetic irradiation. Additionally the invention relates to a method of hydrogenating a working solution in a hydrogen peroxide production process, said working solution containing alkyl anthraquinones and/or alkyl hydroanthraquinones dissolved in at least one solvent, to convert said quinones to corresponding alkyl anthrahydroquinones and/or alkyl hydroanthrahydroquinones, wherein the reaction is carried out in the presence of a catalyst under electromagnetic irradiation.
    Type: Application
    Filed: March 14, 2002
    Publication date: December 19, 2002
    Inventors: Reijo Aksela, Juhani Paloniemi