Nitrogen, Halogen Or Additional Oxygen Containing Patents (Class 552/266)
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Patent number: 8957212Abstract: There is intended to provide the novel compounds which generate a base easily when irradiated with long wavelength light (active energy rays), a photobase generator containing the compounds and a photobase generation method, and the present invention relates to the compounds represented by the general formula [1], a photobase generator containing the compounds and a photobase generation method: (wherein, Ar represents any of groups with specific structures selected from the group consisting of an anthracenyl group, an anthraquinonyl group and a pyrenyl group; R1 and R2 each independently represent a hydrogen atom or a linear, branched or cyclic alkyl group having 1 to 10 carbon atoms, or represent ones which can form an alicyclic ring containing nitrogen atom(s) or an aromatic ring containing nitrogen atom(s) together with a nitrogen atom to which they are bound, which the rings having 3 to 8 carbon atoms which may have a substituent, R3 and R4 each independently represent a hydrogen atom, a linear, brancType: GrantFiled: December 1, 2009Date of Patent: February 17, 2015Assignee: Wako Pure Chemical Industries, Ltd.Inventors: Ayako Kuramoto, Motoshige Sumino, Nobuhiko Sakai
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Publication number: 20120090995Abstract: Devices for detecting an analyte comprising a redox active analyte sensitive material on a working electrode and computer assisted signal acquisition and processing.Type: ApplicationFiled: March 25, 2010Publication date: April 19, 2012Applicant: SENOVA SYSTEMS, INC.Inventors: Lee Leonard, Joseph A. Duimstra, Eric Lee, Mark Micklatcher, Victor Simonyi, Gregory G Wildgoose, Joseph I. Keto, Anton Seidl
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Publication number: 20110233048Abstract: There is intended to provide the novel compounds which generate a base easily when irradiated with long wavelength light (active energy rays), a photobase generator containing the compounds and a photobase generation method, and the present invention relates to the compounds represented by the general formula [1], a photobase generator containing the compounds and a photobase generation method: (wherein, Ar represents any of groups with specific structures selected from the group consisting of an anthracenyl group, an anthraquinonyl group and a pyrenyl group; R1 and R2 each independently represent a hydrogen atom or a linear, branched or cyclic alkyl group having 1 to 10 carbon atoms, or represent ones which can form an alicyclic ring containing nitrogen atom(s) or an aromatic ring containing nitrogen atom(s) together with a nitrogen atom to which they are bound, which the rings having 3 to 8 carbon atoms which may have a substituent, R3 and R4 each independently represent a hydrogen atom, a linear, brancType: ApplicationFiled: December 1, 2009Publication date: September 29, 2011Applicant: WAKO PURE CHEMICAL INDUSTRIES, LTD.Inventors: Ayako Kuramoto, Motoshige Sumino, Nobuhiko Sakai
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Patent number: 7268162Abstract: The invention relates to aloe-emodin (AE) derivatives and their use as anticancer drugs. Saids derivatives show a specific cytotoxicity to tumour cells, also of neuroectodermal origin, to which they may in particular act as aloe-emodin prodrugs. Said pharamcological profile makes them particularly suitable for use in the treatment of neoplasias. Thereofore, pharmaceutical compositions containing said compound may be usefully used in the treatment of neoplasias. It has surprisingly been found that aloe-emodin derivatives in position 3? (bearing either a positive or negaive charge) exhibit improved sollubility properties and, at the same time, in vitro show cytotoxicity to tumour cells, also of neuroectodermal origin.Type: GrantFiled: May 10, 2002Date of Patent: September 11, 2007Assignee: Universita' Degli Studi di PadovaInventors: Giorgio Palu, Modesto Carli, Teresa Pecere, Giuseppe Zagotto
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Patent number: 7132403Abstract: Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the formula: wherein R1, R2, R3, and R4 are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combination thereof, R is a group containing 1 to 12 carbons such as methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, or combination thereof, and the halogen is I, F, Br, or Cl.Type: GrantFiled: January 20, 2004Date of Patent: November 7, 2006Assignees: Board of Trustees of Michigan State University, Regents of the University of CaliforniaInventors: Robert H. Cichewicz, Muraleedharan G. Nair, James H. McKerrow
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Patent number: 6903076Abstract: Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the formula: wherein R1, R2, R3, and R4 are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combination thereof, R is a group containing 1 to 12 carbons such as methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, or combination thereof, and the halogen is I, F, Br, or Cl.Type: GrantFiled: November 26, 2003Date of Patent: June 7, 2005Assignees: Board of Trustees of Michigan State University, The Regents of the University of CaliforniaInventors: Robert H. Cichewicz, Muraleedharan G. Nair, James H. McKerrow
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Patent number: 6875746Abstract: Anthraquinones are described which have anticancer or antitumor activity and which are useful for inhibiting cancer cells and cells comprising tumors in vitro or in vivo. Preferably, the anthraquinones have the chemical formula: wherein R1 is selected from the group consisting of hydrogen, alkyl, and substituted alkyl; R2 is a group containing 1-12 carbons selected from the group consisting of alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate and combinations thereof; and R3 is a group containing 1 to 12 carbons selected from the group consisting of methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, and combinations thereof.Type: GrantFiled: January 31, 2003Date of Patent: April 5, 2005Assignee: Board of Trustees of Michigan State UniversityInventors: Muraleedharan G. Nair, Robert H. Cichewicz, Navindra P. Seeram, Yanjun Zhang
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Patent number: 6838443Abstract: Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the formula: wherein R1, R2, R3, and R4 are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combination thereof, R is a group containing 1 to 12 carbons such as methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, or combination thereof, and the halogen is I, F, Br, or Cl.Type: GrantFiled: November 26, 2003Date of Patent: January 4, 2005Assignees: Board of Trustees of Michigan State University, The Regents of the University of California, The United States of America as represented by the Department of Veterans AffairsInventors: Robert H. Cichewicz, Muraleedharan G. Nair, James H. McKerrow
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Patent number: 6800615Abstract: Anthraquinones are described which are antihelminthic and in particular, are useful in compositions for inhibiting Schistosoma sp. in vitro or in vivo. The preferred anthraquinones have the formula: wherein R1, R2, R3, and R4 are each hydrogen, hydroxy, halogen, alkyl, substituted alkyl, alkene, substituted alkene, alkyne, aryl, substituted aryl, cyclic, substituted cyclic, acid group, carbohydrate, or combination thereof, R is a group containing 1 to 12 carbons such as methyl, alkyl, substituted alkyl, aldehyde, hydroxy, hydroxymethyl, acid group, carbohydrate, or combination thereof, and the halogen is I, F, Br, or Cl.Type: GrantFiled: December 12, 2002Date of Patent: October 5, 2004Assignees: Board of Trustees of Michigan State University, The Regent of the University of California, The United States of America as represented by the Department of Veterans AffairsInventors: Robert H. Cichewicz, Muraleedharan G. Nair, James H. McKerrow
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Patent number: 6491847Abstract: A novel class of discotic liquid crystals represented by the following formula was synthesized, and a layer thereof was incorporated in an organic electroluminescence device.Type: GrantFiled: September 20, 2000Date of Patent: December 10, 2002Assignee: Canon Kabushiki KaishaInventors: Takao Takiguchi, Shinjiro Okada, Akira Tsuboyama, Shinichi Nakamura, Takashi Moriyama
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Patent number: 6057461Abstract: The invention relates to a process for the preparation of substituted anthraquinones represented by the general formula (I): ##STR1## by Diels-Alder reaction between a 1,4-naphthoquinone of general formula (II): ##STR2## and an acyclic diene of formula (III):CH.sub.2 .dbd.CR--CH.dbd.CH--OR.sub.3 (III)followed by an oxidizing deprotection reaction by means of the Jones reagent, in order to obtain the substituted anthraquinone of general formula (I).Application to the preparation of rheins of use in pharmaceuticals.Type: GrantFiled: October 2, 1998Date of Patent: May 2, 2000Assignee: GirexInventors: Cyril Estanove, Fran.cedilla.ois Pruvost
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Patent number: 5162545Abstract: Malonic acid dyes capable of forming polycondensation products have the formula ##STR1## where R.sup.1 and R.sup.2 are each independently of the other hydroxyl, C.sub.1 -C.sub.6 -alkoxy, chlorine or bromine,R.sup.3 is hydrogen or C.sub.1 -C.sub.6 -alkyl,A is C.sub.1 -C.sub.20 -alkylene which may be interrupted by oxygen atoms or by imino or C.sub.1 -C.sub.4 -alkylimino groups, andChr is the radical of a chromophore derived from an anthraquinone, perylene, disazo or trisazo dye or else, when R.sup.3 is C.sub.1 -C.sub.6 -alkyl, from a monoazo dye.Type: GrantFiled: October 12, 1990Date of Patent: November 10, 1992Assignee: BASF AktiengesellschaftInventors: Karl-Heinz Etzbach, Karin H. Beck, Gerhard Wagenblast
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Patent number: 4966918Abstract: The present invention concerns compounds of the formula: ##STR1## wherein R.sup.1 hydrogen, a hydroxyl group or a methoxy group;R.sup.2 is hydrogen or a methyl group;R.sup.3 is hydrogen or a methyl group;Y is a halogen, a secondary amino group or a tertiary amino group; andZ is hydrogen or a halogen.The invention further concerns pharmaceutical compositions which comprises the above-identified compound or the acid salts thereof, and the use of the compound or compositions for treating a malignancy in a subject.Type: GrantFiled: January 27, 1989Date of Patent: October 30, 1990Assignee: Sloan-Kettering Institute for Cancer ResearchInventors: Kyoichi A. Watanabe, Masao Koyama
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Patent number: 4924015Abstract: Anthraquinones having .alpha.,.alpha.-(dialkyl)alkyl groups which are functionally substituted, for example by --COOH or --CONH--NH.sub.2, are described. Compositions which contain such anthraquinones, an aminoalcohol and an epoxy resin with or without a hardener are suitable for preparing metallic coatings and images on the cured composition by exposure to light and currentless metal deposition.Type: GrantFiled: June 20, 1988Date of Patent: May 8, 1990Assignee: Ciba-Geigy CorporationInventors: Frederick H. Howell, Rudolf Duthaler, Jurgen Finter, Konrad Oertle, Visvanathan Ramanathan