Abstract: The present invention relates to new organodisilanes or carbodisilanes, a process for manufacturing the same and their use, in particular, as surface active agents, especially as spreading agents.

Abstract: Disclosed herein are metal-terpyridine complexes and their use in hydrosilylation reactions.

Abstract: An object of the present invention is to provide an oil agent composition which can improve the reduction in operability occurring when an oil agent composition containing a silicone compound is used as the main component and the reduction in the physical properties of the carbon fiber bundle occurring when a non-silicone-based oil agent composition is used. The oil agent composition for acrylic precursor fibers for carbon fibers of the present invention contains 1 to 10 wt % of a modified polydimethylsiloxane including a unit having a specific alkyl chain, at least one unit selected from the group consisting of a unit having a specific polyethylene oxide chain, a unit having a specific polyglycerin chain, and a unit having a specific polyether chain, and optionally a unit having a specific polydimethylsiloxyalkyl chain.

Abstract: The present patent application relates to a reactive ceramic binder in liquid form which is suitable for producing ceramic products from ceramic powder, characterized in that the reactive, liquid ceramic binder comprises liquid organomodified siloxane compounds having organoalkoxysiloxane units of the general formula (I) where the radicals R1 are, independently of one another, identical or different alkyl, alkaryl or aryl radicals which may be interrupted by ether functions, the radicals R2 are, independently of one another, identical or different radicals selected from the group consisting of H and/or alkyl radicals having from 1 to 6 carbon atoms, the radicals R3 are, independently of one another, identical or different divalent, saturated or unsaturated hydrocarbon radicals which have from 1 to 30 carbon atoms and may be interrupted by ether functions and a is greater than or equal to 0 and less than or equal to 2.

Abstract: The present invention provides curable materials, medical devices incorporating such materials, wherein the curable materials are capable of releasing hydrolyzable leaving agents upon hydrolysis that can form agents (e.g., pharmaceutically active agents), and methods of making and using such materials and devices.

Abstract: A silicon-containing film-forming material includes at least one organosilane compound shown by the following general formula (1). wherein R1 to R6 individually represent a hydrogen atom, an alkyl group having 1 to 4 carbon atoms, a vinyl group, a phenyl group, a halogen atom, a hydroxyl group, an acetoxy group, a phenoxy group, or an alkoxy group, provided that at least one of R1 to R6 represents a halogen atom, a hydroxyl group, an acetoxy group, a phenoxy group, or an alkoxy group, and n represents an integer from 0 to 3.

Abstract: Disclosed is a process for production of a substituted benzene, which comprises intramolecularly and/or intermolecularly trimerizing a triple bond in an alkyne in the presence of a transition metal catalyst to yield a substituted benzene compound. In the process, the transition metal catalyst is prepared from an iminomethylpyridine represented by the formula (1) or (2), a transition metal salt or a hydrate thereof, and a reducing agent in a reaction system and is used to perform the trimerization. The process can be used in any one of the intramolecular cyclization of a triyne compound, the cyclization of a diyne compound or an alkyne compound and the intermolecular cyclization of three molecules of an alkyne compound, is excellent in economic effectiveness and operability, and is practically advantageous.

Abstract: The invention relates to a hydrophobic fumed silica which is obtained by grinding a fumed silica which, as a result of silanization, has trimethylsilyl groups fixed on the surface; and to coating formulations comprising this silica.

Abstract: Silicone-polyether block copolymers prepared by organomodification of branched polysiloxanes having terminal and/or lateral SiH functions or linear polysiloxanes having lateral and/or terminal SiH functions by means of polyethers or polyether mixtures, characterized in that the polyethers used have a polydispersity Mw/Mn in the range from 1.0 to 1.5 and/or ratios Mn/MWIN and Mw/MWIN in the range from 0.7 to 1.3, their preparation and use and also polymer articles produced therewith.

Abstract: A silyl (meth)acrylate compound containing a siloxy group having a bulky substituent is provided. The compound is represented by the following general formula (1): wherein R1 and R2 are independently a C3-10 monovalent branched hydrocarbon group having a hydrocarbon group at ? or ? position or a monovalent C3-10 cyclic hydrocarbon group; R3, R4, and R5 are independently an unsubstituted or substituted C1-20 hydrocarbon group or a siloxy group represented by the following general formula (2): —OSiR7R8R9??(2) wherein R7, R8, and R9 are independently an unsubstituted or substituted C1-20 hydrocarbon group; and R6 is hydrogen atom or methyl group. This compound is hydrolyzed at a reduced speed, and use of a polymer obtained by copolymerization with an alkyl methacrylate is capable of suppressing attachment of marine organisms to the ship with no or reduced biocide, and this polymer is useful for a hydrolytic self-polishing paint.

Abstract: The present invention has its object to provide a liquid-form modified product of polyhedral polysiloxane which is excellent in moldability and transparency, and a composition produced using the modified product. In addition, the present invention can provide an easy-to-handle modified product and composition. The present invention provides a modified product of polyhedral polysiloxane which is obtainable by modifying a polyhedral polysiloxane compound (a) with a compound (b), and a composition containing the modified product. The polyhedral polysiloxane compound (a) has an alkenyl group and/or a hydrosilyl group, and the compound (b) has a hydrosilyl group and/or an alkenyl group each capable of hydrosilylation with the component (a).

Abstract: The present invention is to provide a silicone having (meth)acryl groups on both ends of a molecule and represented by the formula (I): wherein R1 is represented by the following formula: wherein n is 3 or 4, k is an integer of from 1 to 15, j is an integer of from 0 to 15, and Q2 is a methyl group or a hydrogen atom; R2 is, independently of each other, a group selected from the group consisting of hydrocarbon groups and halogenated hydrocarbon groups, both having 1 to 10 carbon atoms; R3 is a group represented by the following formula: —CmH2mO(C2H4O)x(C3H6O)yQ1 wherein m is 3 or 4, x is an integer of from 1 to 15, y is an integer of from 0 to 15, and Q1 is a methyl group or a hydrogen atom; a is an integer of from 1 to 500; and b is an integer of from 1 to 100, with a total of a and b being 50 to 500.

Abstract: An object of the present invention is to provide a process for producing a powder of a cage silsesquioxane compound by simple operations. In the invention, a high-quality powder of a cage silsesquioxane compound is obtained by reacting a partially cleaved structure of a cage silsesquioxane having a specific structure with an alkoxysilane to obtain a solution containing the cage silsesquioxane compound and further by treating the solution in a thin-film distillation machine.

Abstract: Siloxy-substituted silane-containing polymerizable silicones are prepared in high purity by metering a substituted alkoxysilane into a mixture of disiloxane, acetic acid, and acid catalyst, adding acetyl chloride, separating an acidic phase from a product phase, and adding hexamethyldisilazane to the product phase, which is then distilled.

Abstract: Polymerizable siloxy-substituted silanes are obtained in high yield and purity by adding a substituted alkoxysilane to a mixture of disiloxane, acetic acid, sulfuric acid, and optionally an acidic catalyst, separating a product phase from an acidic phase, adding hexamethyldisilazane to the product phase and filtering off a resulting salt, followed by distillation.

Abstract: Silicone composites subject to reticulation or reticulated, particularly for creating a coating or water-repellent and anti-adhesive film for flexible substrates such as paper or similar in the form of natural or synthetic polymer films. These compounds contain reticulating polyorganosiloxanes that have SiH units and unsaturated polyorganosiloxanes, preferably vinylated, suitable for reacting with the reticulating agent in an addition reaction and in the presence of platinum to form the reticulated anti-adhesive coating on the flexible substrate, plus at least one additive (D) to promote adhesion to it.

Abstract: A process for preparing a cyclic organosilane using a solvent that promotes ring-closure reactions between an organosilane compound and a dihalo organic compound is disclosed. The ring-closure reactions may form a 4-, 5- or 6-member cyclic organosilane. The process involves a mixture including a dihalo organic compound, an organosilane having at least two functional groups, a solvent and magnesium (Mg). The two functional groups in the organosilane may include halogen, alkoxy or a combination thereof. In the presence of Mg, a Grignard intermediate is formed from the dihalo organic compound in the mixture. The solvent favors intra-molecular or self-coupling reactions of the Grignard intermediate. The intra-molecular or self-coupling reaction promotes ring-closure reaction of the Grignard intermediate to form the cyclic organosilane.

Abstract: A polycarbonate polymer or copolymer comprising pendant silylated dihydroxy aromatic compound of the formula (1a); wherein Ga and Gb are each independently C1-12 alkyl, —OSi(C1-12 alkyl)3, C1-12 arylalkyl, or —OSi(C1-12 arylalkyl)3; Za and Zb are each independently a straight or branched C2-18 is alkylene, a C8-18 arylalkylene, or a C8-18 alkylarylene, Xa is a direct bond, a heteroatom-containing group, or a C1-18 organic group, and r and s are each independently 1 or 2 is disclosed.

Abstract: Compounds containing carbon-carbon double bonds and/or carbon-carbon triple bonds are hydrosilylated with linear organopolysiloxanes having diorganosiloxy units and Si—H groups, produced by reacting diorganodichlorosilanes and monochlorosilanes and optionally dichlorosilanes with water in a first step, where at least one of the monochlorosilanes or dichlorosilanes contain Si—H groups to give a partial hydrolysate and gaseous hydrogen chloride, and in a second step, treating the partial hydrolysate with water to remove SiCl groups still present to form hydrochloric acid, and producing a hydrolysate containing the organopolysiloxanes.

Abstract: A method of producing an organosilicon compound includes substituting at least an OR1 group of a compound shown by the following general formula (1) to obtain a compound shown by the following general formula (2), Si(OR1)3-mY1m—R2—Si(OR3)3-nY2n??(1) Si(OR4)3-mY1m—R2—Si(OR4)3-nY2n??(2).

Abstract: In a method of forming an interlayer insulating film by plasma CVD, an organic siloxane compound including one or more silicon atoms each having at least three or more units each represented by a general formula, —O—Si(R1R2)—OR3 (wherein R1 and R2 are the same as or different from each other and are a methyl group, an ethyl group or a propyl group, and R3 is the same as or different from R1 and R2 and is a methyl group, an ethyl group, a propyl group or a phenyl group) is used as a raw material.

Abstract: A composition having a first hydrophobic moiety linked to a spacer, which is linked to a second hydrophobic moiety to form a Gemini surfactant is provided. Each hydrophobic moiety of the foregoing composition may include silicon. A method for linking a first hydrophobic moiety to a second hydrophobic moiety using a spacer to form a Gemini surfactant is provided. A pesticide having an active ingredient and a composition having a first hydrophobic moiety linked to a spacer, which is linked to a second hydrophobic moiety to form a Gemini surfactant is also provided.

Abstract: The invention concerns the general field of high speed silicone coating on various flexible cylinders, such as paper or synthetic polymer (polyolefin, polyester), or textile sheets. The invention concerns an efficient method for controlling the onset of fog when coating flexible supports with a liquid silicone composition precursor of crosslinked coatings, said coating being performed using a cylinder-type coating device operating at a high speed.

Abstract: The invention relates to a polymerizable composition which is characterized in that it contains at least one filler that is surface-functionalized with groups of formula (I), wherein groups of formula (I) (A)a-Z-Y—R2—SiR13?m—(O—)m ??(I), are bonded to the filler via at least one oxygen atom that is bound to the silicon atom of the group of formula (I). The invention also relates to a process for the preparation of the composition according to the invention and its use in particular as a dental material.

Abstract: Intermediates useful in the preparation of the antiviral agent entecavir are disclosed. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various processes useful in the preparation of entecavir are also disclosed.

Abstract: The disclosure herein relates to organofunctional silanes and mixtures of organofunctional silanes possessing mercaptan and hydrocarbyl and/or heterocarbyl functionality. These silanes reduce or eliminate the generation of volatile organic compounds (VOC's) during use, aid in the processing of filled elastomeric materials and enhance the end-use properties of the filled elastomer. The present disclosure relates to a rubber composition and article comprising these silanes.

Abstract: The present invention provides a polysilane-supported transition metal catalysts or a polysilane/inorganic compound-supported transition metal catalysts, wherein various types of transition metals are supported by polysilane compounds, or combination of polysilanes and inorganic compounds. The catalysts of the present invention are hardly soluble in hydrocarbons and alcohols and are useful as catalysts in heterogeneous system for various organic synthetic reactions using the above solvents. Polysilanes supporting transition metals are easily crosslinkable by thermal treatment, microwave irradiation, UV irradiation or chemical methods such as hydrosilylation reaction and are changed to be insoluble in various solvents keeping high catalytic activity. Moreover, the stability and operability of polysilane-supported transition metal catalysts will be improved by the support thereof on inorganic compounds.

Abstract: Organosilicon compounds having units of the formula RdXeSiY(4-d-e)/2??(I), where X is OH or a hydrolyzable radical and Y is a divalent hydrolyzable radical are useful in crosslinkable compositions, in particular in compositions crosslinkable via a condensation reaction, preferably as sealing compounds.

Abstract: A silyl group-containing polymer which can be cured quickly and strongly, and from which a cured product excellent in antifouling properties and weather resistance while maintaining favorable rubber elasticity can be obtained, and having the following formula (1): wherein R1: a group having a hydroxyl group(s) removed from a monohydroxy or polyhydroxy compound having t hydroxyl group(s) in its molecule, R2: a bivalent organic group, R3: a C1-20 monovalent organic group which may have a substituent, X: a hydroxyl group or a hydrolysable group, Y: a bivalent group of the following formula (A) or (B), “a”: an integer of from 1 to 3, r: an integer of from 1 to 1,000, and t: an integer of from 1 to 8, provided that when the silyl group-containing polymer of formula (1) has a plurality of Y's in its molecule, the plurality of Y's may be the same or different, and when t is from 2 to 8, a plurality of monovalent groups bonded to R1 may be the same or different: in the formula (A), R4: a C2-8 alkylene group,

Abstract: Silica particles having 4-30% of an organopolysiloxane grafted to surfaces thereof are provided. A silicone composition loaded with such silica particles has high transparency, minimized permeability to corrosive gases, and improved encapsulation ability.

Abstract: To make an inexpensive chromatographic column and perform chromatography with it, column walls and a column end with a port are molded integrally from plastic. A closure is integrally molded with a port as well. One type of closure includes part of a snap-on fastener integrally molded to it to cooperate with corresponding parts molded integrally with the column walls. In another type of closure for higher pressures, the closure is spin welded to the tubular walls. In still another type of closure for still higher pressures, a retaining plate is pressed into the column to hold the packing in place. The closures have channels molded into them radiating from a port and opening toward packing material such as silica beads or porous polymeric plugs. Filters and secondary seals may be located at the ends to prevent leakage of the packing material. The packing is balanced spherical or spheroid-like derivitized silica packing.

Abstract: The invention provides adducts comprising a carbon nanotube with covalently attached silane moieties, and methods of making such adducts. Examples of silane moieties include trimethoxysilane; hexaphenyldisilane; silylphosphine; 1,1,1,3,5,5,5-heptamethyltrisiloxane; polydimethylsiloxane, poly(N-bromobenzene-1,3-disulfonamide); N,N,N?,N?-tetrabromobenzene-1,3-disulfonamide; hexamethyldisilazane (HMDS); chlorotrimethylsilane (TMCS); trichloromethylsilane (TCMS); an alkyl(alkylamino)silane; a tri(alkoxy)silane; tert-butyldimethylsilane; monochloroaminosilane; dichloroaminosilane; trichloroaminosilane; and dimethylaminosilane.

Abstract: A surfactant of formula 1 (Rf-A)a-Q-([B]k—R)b??Formula 1 wherein a and b are each independently 1 or 2; Rf is a linear or branched perfluoroalkyl radical having from 2 to about 20 carbon atoms, optionally interrupted with at least one oxygen; R is a C1 to C20 linear, branched or cyclic alkyl, or a C6 to C10 aryl; B is —(CH2CHR1O)x—, k is 0 or 1, x is 1 to about 20, A is —(CH2)m[(CHR1CH2O)]s—[(CH2)m(CH)tCHOH(CH2)m]e—, wherein each m is independently 0 to 3, s is 0 to about 30, t is 0 or 1, and e is 0 or 1, R1 is H or CH3, Q is: —OP(O)(O?M+)(O)—, —O—, —S—(CH2)m—C(O)—O—, —SO2—O— —CH2CH2O—C(O)CH2C(OH)(V)CH2C(O)O—; —(CH2CH2O)xCH2CH(OH)—(CH2CH2O)x—(CH2)m—Si[OSi(R2)3]2—, —SO2NR2—, —(CH2CH2O)zC(O)CH(SO3?M+)CH2C(O)(OCH2CH2)z— wherein z is 1 to about 15, or a bond when s is a positive integer, V is —C(O)OR3 and R3 is H, CH3 or Rf; R2 is C1 to C4 alkyl, and M+ is a Group 1 metal or an ammonium (NHxR2y)+ cation wherein x+y=4, and R2 is C1 to C4 alkyl, provided that when Q is —OP(O)(O?M+)(O)— or when Q is —(

Abstract: Polysiloxane hydrolyzates are neutralized by treating polysiloxane hydrolyzates containing residual acidic constituents with carbon, and then the carbon is removed from the treated neutralized polysiloxane hydrolyzate. Some examples of polysiloxane hydrolyzates that can be treated are hydride functional polysiloxane hydrolyzates and polydiethylsiloxane hydrolyzates. The carbon neutralizing agent especially preferred is carbon derived from bituminous coal. The carbon is removed from the treated neutralized polysiloxane hydrolyzate by passing it through solid liquid separation devices such as plate and frame filter presses, polishing filters, and post filters for removing fines.

Abstract: A multi-functional silsesquioxane, method of making the same, and coatings incorporating the same, including a polyhedral silsesquioxane including at least one first face and at least one second face that is spaced apart from the at least one first face; at least one first functionality bonded to the at least one first face; and at least one second functionality different from the first functionality, and being bonded to the at least one second face. In one particular respect, silica for the silsesquioxane may be derived from rice hull ash via an octa(tetramethylammonium)silsesquioxane octaani{dot over (o)}n.

Abstract: The present invention relates to new organodisilanes or carbodisilanes, a process for manufacturing the same and their use, in particular, as surface active agents, especially as spreading agents.

Abstract: A composition includes a copolymer including a mixture of monomeric units having structures (A), (B), and (C), and one or more of structures (D) or (E): HSiO(3-a)/2(OH)a ??(A) Si(3-b)/2(OH)b—CH2)n—SiO(3-c)/2(OH)c ??(B) R1SiO(3-d)/2(OH)d ??(C) MeSi(3-e)/2(OH)e ??(D) R2SiO(3-f)/2(OH)f ??(E) wherein a, b, c, d, e, and f are independently from 0 to 2, n is from 0 to about 10, R1 is a chromophore, and R2 is a hydrophilic group.

Abstract: Novel ester derivatives of ascorbic acid and 2-keto-acid saccharides are provided wherein the ester is introduced by ester bond formation between at least one hydroxy-functionality on the ascorbic acid or 2-keto-acid saccharide and a carboxy-functional organosiloxane, or between a 2-keto-gulonic acid and a hydroxy-functional organosiloxane, as well as methods for their synthesis. Treatment, cosmetic, and personal care formulations comprising the novel esters are also provided, including controlled release forms thereof.

Abstract: Organic electrolyte solutions and lithium batteries employing the same are provided. In one embodiment, an organic electrolyte solution includes a silane compound. The inventive organic electrolyte solutions prevent crack formation caused by volumetric changes in the anode active material during charging/discharging of the battery. This improves charge/discharge characteristics, resulting in improved battery stability, reliability, and charge/discharge efficiency, which is a dramatic improvement over conventional organic electrolyte solutions, which have higher irreversible capacities due to the decomposition of polar solvents.

Abstract: Monomers for polymers having high oxygen permeability, high water content and a low modulus of elasticity are provided, and polymers and ophthalmic lenses comprised of said monomers are provided. They are monomers represented by formula (1) or (2) below: X—O—(CH2CH2CH2O)m—(CH2)n—A ??(1) wherein, X is a polymerizable group having carbon-carbon unsaturated bonds; A is a siloxanyl group; R is H or a methyl group; m is an integer of 1 to 10; m? is an integer of 2 to 10; and n is an integer of 2 to 10.

Abstract: A ?,?-unsaturated carboxylic acid silyl ester is prepared by reacting an ?,?-unsaturated carboxylic acid ester with a hydrosilane or hydrosiloxane in the presence of tris(pentafluorophenyl)borane. ?,?-Unsaturated carboxylic acid derivatives are readily prepared through fewer steps and in high yields.

Abstract: Disclosed are colorant compounds of the formula wherein R, R1, R2, R3, and R4 each, independently of the others, is an alkyl group, an aryl group, an arylalkyl group, or an alkylaryl group, and wherein R, R1, R2, R3, and R4 each can be joined to a phenyl moiety to form a ring, each R?a, R?b, and R?c, independently of the others, is a halogen atom, an alkyl group, an alkoxy group, a nitrile group, a nitro group, an amide group, or a sulfonamide group, z1, z2, and z3 each, independently of the others, is an integer of 0, 1, 2, 3, or 4, n is an integer representing the number of carbon atoms in each repeat alkylene oxide unit, x is an integer representing the number of repeat alkylene oxide units, D is an anion, and g is the charge on the anion, wherein said colorant has no more than one —OH, —SH, or primary or secondary amino group per molecule.

Abstract: An organic silicon compound, having high reactivity, represented by the following Formula (1): wherein R and M are defined in the specification. The organic silicon compound is produced by reacting polysilsesquioxane, which is obtained by hydrolyzing a silane compound having three hydrolyzable groups and represented by the following Formula (2), with a monovalent alkaline metal hydroxide in an organic solvent, or by subjecting the silane compound having three hydrolyzable groups to hydrolysis and polycondensation in the presence of an organic solvent and an alkaline metal hydroxide: R—Si X3??(2) wherein R is the same as in Formula (1) and X represents a hydrolyzable group.

Abstract: Polymerizable silicon-containing compounds of formula (1) wherein R1 is hydrogen, halogen or monovalent organic group are polymerized into polymers.

Abstract: The invention provides a device for selective molecular recognition, the device comprising a sensing portion, wherein said sensing portion includes a substrate having coated thereon a layer comprising a non-volatile, small molecule compound having at least two pendant and terminal unsaturated groups, each being functionalized with at least one halogen substituted alcohol or phenol functional group. The compound of the invention preferably has one of the following general formulae: wherein A is a core moiety; B is a pendant and terminal unsaturated group; q is at least 1; r is at least 2; X is a linking group; and n is an integer designating the number of repeating units from 1 to 3, with the proviso that, if n is greater than 1, then the B groups differ from each other in at least two of the repeating units. The device is used to detect the molecules of a hydrogen bond accepting vapor such as an organophosphonate or nitroaromatic vapor.

Abstract: The object of the present invention is to provide a new kind of silicon compound having an ester-type organic functional group and a new method for providing a T8-silsesquioxane compound having a hydroxyl group by using said silicon compound as the starting material. A silicon compound represented by formula (1) is obtained through the production process characterized by using a silicon compound represented by formula (2). wherein: in formula (1), each of seven R1 group is independently selected from the group consisting of hydrogen, alkyl, substituted or unsubstituted aryl, and substituted or unsubstituted arylalkyl and A2 is a hydroxyl-terminal organic functional group, and in formula (2), each of R1 group is the same as R1 in formula (1), and A1 is an organic functional group containing an acyloxy group.

Abstract: An antifoam formulations comprise (A) antifoam agent based on siloxanes and (B) branched polyether/polysiloxane copolymers comprising structural units of the formula Y[—CnH2n—(R2SiO)m—Ap—R2Si—G]x??(I) in which Y is a multivalent, optionally heteroatom-containing hydrocarbon radical, R are monovalent optionally halogenated hydrocarbon radicals, A is a radical —R2Si—R2—(R2SiO)m—, G is a monovalent radical —CfH2f-2k—Z or a divalent radical —CnH2n— bonded to a radical Y, Z —(R6)v—(OCH2CH2)a[OCH2CH(CH3)]b[OCH2CH(CH2CH3)]c—OR3, in which R3 is hydrogen, a hydrocarbon radical, or a radical R—C(O)—, R6 is a divalent hydrocarbon radical, v is 0 or 1, a, b and c are 0 or an integer between 1 and 1000, the sum (a+b+c) being from 2 to 2000, x is 3 to 10, f is 2 to 12, k is 0 or 1, n is 2 to 12, m is at least 1, and p is 0 or a positive integer, the branched polyether/polysiloxane copolymers (B) containing on average at least one group Z.

Abstract: A silane compound of the following formula (1) having two or more protected functional groups A-R—Si(CH3)nX3-n??(1) wherein A represents a group of the following formula wherein R1, R2 and R3 each independently represent a monovalent hydrocarbon group having 1 to 10 carbon atoms, a is an integer of 1 to 10, and b is an integer of 1 to 10, or wherein R1, R2 and R3 are as defined above, R represents a linear or branched, divalent hydrocarbon group having 2 to 10 carbon atoms, X represents a halogen atom or an organoxy group having 1 to 10 carbon atoms, and n is 0, 1 or 2 is prevented from the reaction of the functional groups per self when undergoing modification or treatment. When the protection is removed after introduction of the protected functional groups, quantitative and efficient introduction of the two or more functional groups is ensured, resulting in more developed effects of modification and addition.

Abstract: Processes are disclosed for preparing the antiviral agent entecavir. A resin adsorption process for the isolation and purification of entecavir is also disclosed. Various intermediates useful in the preparation of entecavir are also disclosed.

Abstract: 1-Deoxybaccatin III, 1-deoxytaxol and 1-deoxy taxol analogs and method for the preparation thereof.