Polycarboxylic Acid Patents (Class 560/176)
  • Patent number: 4096177
    Abstract: A process for the synthesis of Ibuprofen, p - isobutyl hydrotropic acid is described based upon the aromatization reaction which takes place when a dialkyl .alpha.-acetyl-.alpha.-[(5-methyl-3-oxo)-hexyl]-.alpha.'-methyl-succinate (II) is heated at temperatures of about 200.degree. with a strong acid, or a salt of a strong acid with an organic base.
    Type: Grant
    Filed: November 30, 1976
    Date of Patent: June 20, 1978
    Inventor: Leandro Baiocchi
  • Patent number: 4085274
    Abstract: 4-OXOPENTADECANEDIOIC ACID IS PREPARED BY OXIDIZING A .alpha.-CYCLODODEC-1-ENYLPROPIONIC ACID DERIVATIVE HAVING ONE OF THE FOLLOWING CHEMICAL FORMULAE AT ITS ETHYLENIC DOUBLE BOND WITH OZONE. ##STR1## The compound is useful as an intermediate for a musk perfume compound. The compound having the formula II is selectively prepared from cyclododecanone and di-alkyl succinate.
    Type: Grant
    Filed: May 26, 1976
    Date of Patent: April 18, 1978
    Assignee: Daicel Ltd.
    Inventors: Katuhiko Takahashi, Kyozo Arimoto, Yoshiyuki Arai, Tsuyoshi Morinaga, Yuji Nakazawa