Carboxyl, Or Salt Thereof, Bonded Directly To A Ring Patents (Class 562/473)
-
Patent number: 4721808Abstract: A crude p-hydroxymethylbenzoic acid compound containing 4-carboxybenzaldehyde is purified and decolorized by hydrogenation in the presence of a platinum on carbon catalyst. 4-carboxybenzaldehyde is hydrogenated to p-hydroxymethylbenzoic acid. Toluic acid is not a product of the hydrogenation process.Type: GrantFiled: April 21, 1987Date of Patent: January 26, 1988Assignee: Amoco CorporationInventors: Lawrence D. Lillwitz, Steven A. Cerefice
-
Patent number: 4720505Abstract: Compounds having the formula: ##STR1## are antagonists of leukotrienes of C.sub.4, D.sub.4 and E.sub.4, the slow reacting substance of anaphylaxis. These compounds are useful as anti-asthmatic, anti-allergic and anti-inflammatory agents.Type: GrantFiled: November 13, 1984Date of Patent: January 19, 1988Assignee: Merck Frosst Canada, Inc.Inventors: Patrice C. Belanger, John W. Gillard, Joshua Rokach
-
Patent number: 4692552Abstract: This invention relates to methods of preventing or reducing the degradation of elastin and other proteins and thereby preventing or retarding the disease states caused by said degradation by administering compounds of the formula: ##STR1## or their pharmacologically acceptable salts.Type: GrantFiled: February 18, 1986Date of Patent: September 8, 1987Assignee: G. D. Searle & Co.Inventors: Richard A. Mueller, Richard A. Partis
-
Patent number: 4691043Abstract: Benzoic acid derivatives with the general formula: ##STR1## in which: A represents a straight or branched alkyl chain with 5 to 10 carbon atoms,X represents the oxygen atom or a direct bond,R represents hydrogen or an alkyl group with 2 to 6 carbon atoms, possibly substituted by an alcohol function,and the salts of the said derivatives.These derivatives display antimicrobial activity and are suitable as antiseptics, disinfectants and preservatives, particularly in the fields of pharmaceuticals, cosmetology and agri-foodstuffs.Type: GrantFiled: January 7, 1986Date of Patent: September 1, 1987Assignee: SanofiInventors: Henri Demarne, Robert Filhol, Madeleine Mosse
-
Patent number: 4686235Abstract: Substituted cinnamyl-2,3-dihydrobenzofurans and analogs were prepared from the nucleophlic substitution of a cinnamylhalide with a 2,3-dihydrobenzofuran anion or an analog thereof. These compounds were found to be potent topical anti-inflammatory agents.Type: GrantFiled: August 12, 1985Date of Patent: August 11, 1987Assignee: Merck & Co., Inc.Inventors: Michael N. Chang, Norman P. Jensen, Milton L. Hammond, Robert A. Zambias, John McDonald, Kathleen M. Rupprecht
-
Patent number: 4684737Abstract: A process for producing a substituted phthalic acid which comprises heating a substituted tetrahydrophthalic acid compound having a substituent in at least one of the 3-, 4-, 5- and 6-positions in the presence of sulfur to dehydrogenate it, and heat-treating the product in the presence of water optionally together with an organic solvent. As required, the heat-treated product is dehydrocyclized to form a substituted phthalic acid anhydride.Type: GrantFiled: August 17, 1984Date of Patent: August 4, 1987Assignee: Nippon Zeon Co., Ltd.Inventors: Hiroshi Horino, Michiro Ohnaka, Atsushi Hayashi, Yoshiko Ikeno
-
Patent number: 4683244Abstract: A cosmetic preparation for the treatment of seborrhea containing an antiseborrheically effective amount of a p-alkoxy or p-alkybenzyloxy benzoic acid or salt thereof having the formula ##STR1## wherein R is either an alkyl group having from 6 to 18 carbon atoms, or an alkybenzyl group wherein the alkyl moiety has from 3 to 9 carbon atoms, and X is a member selected from the group consisting of hydrogen, an alkali metal, an alkaline earth metal and ammonium, and further containing conventional vehicles and additives; the process for reducing mammalian sebum production by using the above cosmetic preparation; and certain p-alkoxy and p-alkylbenzyloxy benzoic acids or salts thereof of the above formula.Type: GrantFiled: January 10, 1986Date of Patent: July 28, 1987Assignee: Henkel Kommanditgesellschaft auf AktienInventors: Hinrich Moeller, Siegfried Wallat
-
Patent number: 4670465Abstract: Long chain unsaturated hydrocarbon derivatives, having from 13 to 21 carbon atoms, which are substituted at the 1-position by a phenoxy, phenylthio or a phenyl that bear a carboxylic acid group at the ortho, meta or para positions, and up to 4 carbon-carbon triple bonds, methods of preparing them, and pharmaceutical preparations containing them. These compounds are useful as lipoxygenase inhibitors, and therefore as antiinflammatory agents.Type: GrantFiled: May 21, 1986Date of Patent: June 2, 1987Assignee: Syntex (U.S.A.) Inc.Inventors: Angel Guzman, Joseph M. Muchowski
-
Patent number: 4656192Abstract: New tropolone derivatives of the general formula: ##STR1## wherein R.sup.1 represents H or an alkyl group, R.sup.2 represents an alkyl, aryl, aralkyl or heterocyclic group and R.sup.3 represents an alkoxyl, aryl or heterocyclic group or a group of the formula: ##STR2## or R.sup.2 and R.sup.3 may form together a part of a heterocyclic group, their metal complex salts, processes for the preparation thereof and the use thereof as anti-tumor agents.Type: GrantFiled: June 14, 1984Date of Patent: April 7, 1987Assignee: Mect CorporationInventor: Masatoshi Yamato
-
Patent number: 4616090Abstract: New 2-arylimidazopyridines of the general formula I ##STR1## wherein --A.dbd.B-- is (a) --CH.dbd.N-- or (b) N.dbd.CH--, Ar is a phenyl radical, which, in case (a), is substituted by one or two alkynyloxy, cyanomethoxy, carboxymethoxy, and/or alkyloxycarbonylmethoxy groups, and can be substituted by one or two additional hydroxyl, alkyloxy, alkenyloxy and/or alkynyloxy groups, or which in case (b), is substituted by one to three hydroxyl, mercapto, and/or --Z--R groups,Z is --O--, --S-- or --SO-- andR is alkyl, alkenyl, alkynyl, hydroxyalkyl, cyanomethyl, carboxymethyl or alkyloxycarbonylmethyl, the alkyl, alkenyl, alkynyl and hydroxyalkyl groups each having up to 5 C atoms, but wherein in case (b), the phenyl radical is only substituted by hydroxyl or methoxy groups if it has at the same time at least one other substituent differing from these,and their physiologically acceptable salts shown positive inotropic effects.Type: GrantFiled: August 19, 1982Date of Patent: October 7, 1986Assignee: Merck Patent Gesellschaft mit beschrankter HaftungInventor: Rochus Jonas
-
Patent number: 4609741Abstract: Novel phthalic acid derivatives are described which are substituted by 2-propynyloxy groups, of the formula I ##STR1## in which Q.sub.1, and Q.sub.2 independently of one another are --OH or --O.sup.- M.sup.+, or Q.sub.1 and Q.sub.2 together form the grouping --O--, [O.sup.- ].sub.2 M.sub.1.sup.++ or --N(R.sub.2)--, M.sup.+ is an alkali metal ion, a trialkyl ammonium ion having 3-24 carbon atoms or a quaternary ammonium ion and M.sub.1.sup.++ is an alkaline earth metal ion, R.sub.2 is an alkyl group or an unsubstituted or substituted aryl group, n is 1 or 2 and R.sub.1 is hydrogen, if n is 1, or a direct bond, if n is 2, are described. The phthalic anhydrides which are substituted by 2-propynyloxy, of the formula I, can be used for curing epoxy resins, cured products with outstanding physical properties being obtained.Type: GrantFiled: August 9, 1984Date of Patent: September 2, 1986Assignee: Ciba-Geigy CorporationInventors: Roland Darms, Vratislav Kvita, Charles E. Monnier
-
Patent number: 4590291Abstract: An ether derivative of a dihydroxybenzene of the formula ##STR1## in which R.sup.1 is 1 to 3 identical or different substituents selected from hydrogen, halogen, trifluoromethyl, carboxyl, alkyl, alkoxy, alkylmercapto and carbalkoxy, with in each case 1 to 4 carbon atoms in the alkyl and alkoxy groups, andR.sup.2 and R.sup.3 are different and each is an alkyl or alkenyl chain in which 1 or 2 CH.sub.2 chain members are optionally replaced by O, S, CO or a phenylene group, and/or in which the chain is optionally substituted by 1 to 3 identical or different substituents selected from hydroxyl, halogen, trifluoromethyl, phenyl, carboxyl, alkyl, alkoxy, alkylmercapto, carbalkoxy, and acyl, the phenyl radical in turn optionally being substituted by halogen, trifluoromethyl, carboxyl, alkyl, alkoxy, alkylmercapto or carbaloxy, and the abovementioned alkyl, alkoxy and acyl groups in each case containing 1 to 4 carbon atoms, and in which at least one of the radicals R.sup.2 or R.sup.Type: GrantFiled: June 7, 1982Date of Patent: May 20, 1986Assignee: Bayer AktiengesellschaftInventors: Horst Boshagen, Ulrich Horlein, Gerd Reinhardt, Friedel Seuter, Elisabeth Perzborn
-
Patent number: 4585876Abstract: Novel xanthones and thioxanthones of the formula I ##STR1## in which A, X, Y, Z, E and E' are as defined in patent claim 1, are described. A is preferably --S-- and E and E' are preferably bonded in the ortho-position relative to one another. The compounds (I) are suitable, for example, as sensitizers for photocrosslinkable polymers or photocurable compositions, or for use in mixtures with polymers with H donor groups for image formation, in particular electrically conductive coatings and patterns, by means of electroless deposition of metals.Type: GrantFiled: November 14, 1983Date of Patent: April 29, 1986Assignee: Ciba-Geigy CorporationInventors: Walter Fischer, Jurgen Finter, Hans Zweifel
-
Patent number: 4584388Abstract: Aromatic polycarboxylic acids and their anhydrides such as bisphenol A dianhydride are prepared from the corresponding polycarboximides, such as bisphenol A bisimide, by an exchange reaction with phthalic acid or phthalic anhydride and water in the presence of dimethyl-n-butylamine as an exchange catalyst. The use of this amine results in the formation of a product of decreased color, as compared with the use of triethylamine.Type: GrantFiled: January 14, 1985Date of Patent: April 22, 1986Assignee: General Electric CompanyInventor: Jimmy L. Webb
-
Patent number: 4584397Abstract: This invention relates to methods of preventing or reducing the degradation of elastin and other proteins and thereby preventing or retarding the disease states caused by said degradation by administering compounds of the formula: ##STR1## or their pharmacologically acceptable salts.Type: GrantFiled: October 24, 1984Date of Patent: April 22, 1986Assignee: G. D. Searle & Co.Inventors: Richard A. Mueller, Richard A. Partis
-
Patent number: 4536347Abstract: Ruthenium-on-charcoal and ruthenium-on-carbon black catalysts, containing from 0.1 to 5% by weight of iron, for the preparation of olefinically unsaturated alcohols by selective hydrogenation of the corresponding .alpha., .beta.-unsaturated carbonyl compounds in the liquid phase are prepared by modifying the catalyst with iron only after it has been impregnated with the ruthenium compound, and reducing the catalyst with hydrogen at from 400.degree. to 600.degree. C., with thorough mixing.The catalysts according to the invention are particularly useful for improving the industrially difficult hydrogenation of citral to give the soughtafter fragrances geraniol and nerol.Type: GrantFiled: March 19, 1984Date of Patent: August 20, 1985Assignee: BASF AktiengesellschaftInventors: Michael Horner, Matthias Irgang
-
Patent number: 4518797Abstract: Compounds of the formula ##STR1## wherein R.sup.1 is an acyl group or certain optionally halo-substituted hydrocarbyl groups, and X is --CH.sub.2 CH(OCH.sub.3).sub.2, --CH.sub.2 CHO, --CH.dbd.CHOR.sup.2 in which R.sup.2 is acyl, --CHO,--C(O)Cl, --C(O)Br or --C(O)OR in which R is H, a salt-forming cation, an alkyl group or the residue of a pyrethroid alcohol are new pesticides or intermediates therefore. The compounds are prepared using a multi-step synthesis starting from the natural terpene, 3-carene.Type: GrantFiled: March 15, 1979Date of Patent: May 21, 1985Assignee: Shell Oil CompanyInventor: Steven A. Roman
-
Patent number: 4501920Abstract: A salt of 3,4,5-trimethoxybenzoic acid is prepared by initially reacting hydrolyzable tannin with a methylation agent in an alkaline medium under methylation conditions to form methylated tannin and thereafter hydrolyzing the methylated tannin by reaction thereof with a hydrolysis agent under alkaline hydrolysis conditions. The resulting salt can be neutralized to form 3,4,5-trimethoxybenzoic acid, which can readily be recovered.Type: GrantFiled: September 29, 1982Date of Patent: February 26, 1985Assignee: Mallinckrodt, Inc.Inventor: Muthunadar P. Periasamy
-
Patent number: 4499295Abstract: This invention relates to methods of preventing or reducing the degradation of elastin and other proteins and thereby preventing or retarding the disease states caused by said degradation by administering compounds of the formula: ##STR1## or their pharmacologically acceptable salts.Type: GrantFiled: May 9, 1983Date of Patent: February 12, 1985Assignee: G. D. Searle & Co.Inventors: Richard A. Mueller, Richard A. Partis
-
Patent number: 4471134Abstract: A mixture of intermediate products including a carboxylic salt of 3,4,5-trimethoxybenzoic acid (TMB acid) and a dimethoxy benzoic acid derivative of such salt further containing an oxygen anion in the 3,4, or 5 position is prepared by initially reacting hydrolyzable tannin with a methylation agent in an alkaline medium under methylation conditions to form methylated tannin and thereafter hydrolyzing the methylated tanning by reaction thereof with a hydrolysis agent under alkaline hydrolysis conditions. The resulting reaction mixture is then methylated to form a reaction mixture containing methyl 3,4,5-trimethoxybenzoate and a salt of 3,4,5-trimethoxybenzoic acid. TMB acid can be formed in high yield by conversion of both the methyl ester thereof and the salt thereof. Such conversion can be effected by hydrolyzing the reaction mixture followed by acidification thereof.Type: GrantFiled: September 29, 1982Date of Patent: September 11, 1984Assignee: Mallinckrodt, Inc.Inventor: Muthunadar P. Periasamy
-
Patent number: 4461910Abstract: A process for the co-production of an alkylidene dicarboxylate and a carboxylic acid, which comprises hydrogenating a carboxylic acid anhydride in the presence of carbon monoxide and a homogeneous iridium- and/or rhodium-containing catalyst, together with an organo phosphorus (III), arsenic (III), or antimony (III) compound and either molecular oxygen or a phosphorus (V), arsenic (V) or antimony (V) compound containing a X=O moiety, where X is a phosphorus, arsenic or antimony atom.Type: GrantFiled: March 8, 1982Date of Patent: July 24, 1984Assignee: Shell Oil CompanyInventor: Eit Drent
-
Patent number: 4453004Abstract: A process for the preparation of an alkylated phenolic ether comprising reacting a phenolic compound at a temperature of at least the melting point of the phenol and in the absence of a solvent with an alkylating agent until an alkylated phenol is produced.Type: GrantFiled: April 1, 1982Date of Patent: June 5, 1984Assignee: International Telephone and Telegraph CorporationInventor: Randall B. Nelson
-
Catalyzed hydrogenation of terephthalic acid to p-hydroxymethylbenzoic acid using a rhenium catalyst
Patent number: 4448987Abstract: A process is disclosed for preparation of hydroxymethyl aryl monocarboxylic acid compounds by reduction of arylene dicarboxylic acid compounds in the presence of a rhenium catalyst and an aqueous solvent.Type: GrantFiled: November 30, 1982Date of Patent: May 15, 1984Assignee: Standard Oil Company (Indiana)Inventor: Lawrence D. Lillwitz -
Patent number: 4447645Abstract: Disclosed is a process for purification of p-hydroxymethylbenzoic acid containing 4-carboxybenzaldehyde, p-toluic acid and terephthalic acid impurities.Type: GrantFiled: November 30, 1982Date of Patent: May 8, 1984Assignee: Standard Oil Company (Indiana)Inventors: John A. Donohue, James O. Knobloch, Bruce Petty-Weeks, Steven A. Cerefice
-
Patent number: 4408059Abstract: Milbemycin and avermectin macrolides are synthesized by the cyclized linking of separately synthesized northern and southern hemisphere intermediates. The northern hemisphere intermediate is a spiroketal alkenyl aldehyde, and the southern hemisphere intermediate is an aryl alkenyl phosphine oxide anion.Type: GrantFiled: December 4, 1981Date of Patent: October 4, 1983Assignee: University Patents, Inc.Inventors: Amos B. Smith, III, Steven R. Schow
-
Patent number: 4393233Abstract: The subject polymers are novel homopolymers and copolymers. The homopolymers are characterized by relatively high T.sub.g of about 120.degree. C. relative to their T.sub.m of about 250.degree. C., whereby they can readily be fabricated into fibers, films and like structures from the melt, and retain strength above 100.degree. C. The copolymers have T.sub.g 's intermediate between those of the homopolymers of the constituent monomers, and can be fabricated as for the subject homopolymers.Novel processes of obtaining the monomer, p-(1,1-dimethyl-2-hydroxyethyl)benzoic acid, are disclosed.Type: GrantFiled: January 7, 1982Date of Patent: July 12, 1983Assignee: Allied CorporationInventors: Herbert K. Reimschuessel, Bruce T. DeBona
-
Patent number: 4390476Abstract: Phosphonium compounds of the formula(R).sub.3 P.sup..sym. --CH.sub.2 --X--CH.dbd.CH--R.sub.1 --Y.sup..crclbar.in which R is preferably alkyl having 1 to 4 C atoms, cyclohexyl or phenyl, R.sub.1 is a substituted or unsubstituted aromatic radical, especially a phenyl radical, X is phenylene, 4,4'-biphenylene or 1,4- or 2,6-naphthylene and Y.sup..crclbar. is SO.sub.3.sup..crclbar., SO.sub.2.sup..crclbar. or COO.sup..crclbar., a process for their preparation and a process for the preparation of asymetrically substituted fluorescent brightening agents of the formulaZ--CH.dbd.CH--X--CH.dbd.CH--R.sub.1 --Y.sup..crclbar. M.sup..sym.in which R.sub.1, X and Y.sup..crclbar. are as defined above, M.sup..sym. is a cation and Z is preferably a substituted or unsubstituted phenyl or 2-phenyl-triazol-4-yl radical, by reacting a bis-phosphonium compound of the formula ##STR1## in which Q.sup..crclbar. is an anion, with an aldehyde of the formula M.sup..sym. Y.sup..crclbar. --R.sub.Type: GrantFiled: November 5, 1981Date of Patent: June 28, 1983Assignee: Ciba-Geigy CorporationInventor: Michael Marky
-
Patent number: 4348399Abstract: This disclosure describes novel 4-(monoalkylamino)phenyl alkane, alkene and alkyne carbinols, aldehydes, carboxylic acids and derivatives useful as hypolipidemic and antiatherosclerotic agents.Type: GrantFiled: February 2, 1978Date of Patent: September 7, 1982Assignee: American Cyanamid CompanyInventor: Robert G. Shepherd
-
Patent number: 4329292Abstract: A method is provided for continuously converting aromatic bis(ether N-organo substituted phthalimides) to aromatic bis (ether anhydrides) by heating a biphasic aqueous-organic mixture of aromatic bis(ether N-organo substituted phthalimide), phthalic acid and an exchange catalyst in a heated coiled tube reactor to produce an aqueous phase containing aromatic bis (ether phthalic acid) and an organic phase containing N-organo substituted phthalimide which can then be separated and aromatic bis(ether phthalic anhydride) recovered from the aqueous phase.Type: GrantFiled: April 16, 1981Date of Patent: May 11, 1982Assignee: General Electric CompanyInventor: Jimmy L. Webb
-
Patent number: 4329496Abstract: A method is provided for converting aromatic bis(ether N-organo substituted phthalimides) to aromatic bis(ether anhydrides) by heating a bisphasic aqueous-organic mixture of aromatic bis(ether N-organo substituted phthalimide), phthalic anhydride and an exchange catalyst to effect an imide-anhydride exchange producing an aqueous phase containing aromatic bis 4ether phthalic acid) and an organic phase containing N-organo substituted phthalimide. The aromatic bis(ether phthalic acid) is then optionally dehydrated to the corresponding anhydride.Type: GrantFiled: April 3, 1981Date of Patent: May 11, 1982Assignee: General Electric CompanyInventor: Jimmy L. Webb
-
Patent number: 4326055Abstract: This invention is directed to 5,6,7,8-tetrahydro-naphthyl or indanyl stilbene derivatives which are useful as tumor inhibiting agents, in the treatment of neoplasms, dermatological conditions and rheumatic illnesses.Type: GrantFiled: December 15, 1978Date of Patent: April 20, 1982Assignee: Hoffmann-La Roche Inc.Inventor: Peter Loeliger
-
Patent number: 4316860Abstract: Phosphonium compounds of the formula(R).sub.3 P.sup..sym. --CH.sub.2 --X--CH.dbd.CH--R.sub.1 --Y.sup..crclbar.in which R is preferably alkyl having 1 to 4 C atoms, cyclohexyl or phenyl, R.sub.1 is a substituted or unsubstituted aromatic radical, especially a phenyl radical, X is phenylene, 4,4'-biphenylene or 1,4- or 2,6-naphthylene and Y.sup..crclbar. is SO.sub.3.sup..crclbar., SO.sub.2.sup..crclbar. or COO.sup..crclbar., a process for their preparation and a process for the preparation of asymetrically substituted fluorescent brightening agents of the formulaZ--CH.dbd.CH--X--CH.dbd.CH--R.sub.1 Y.sup..crclbar. M.sup..sym.in which R.sub.1, X and Y.sup..crclbar. are as defined above, M.sup.61 is a cation and Z is preferably a substituted or unsubstituted phenyl or 2-phenyl-triazol-4-yl radical, by reacting a bis-phosphonium compound of the formula ##STR1## in which Q.sup..crclbar. is an anion, with an aldehyde of the formula M.sup..sym. Y.sup..crclbar. --R.sub.Type: GrantFiled: May 15, 1980Date of Patent: February 23, 1982Assignee: Ciba-Geigy CorporationInventor: Michael Marky
-
Patent number: 4314070Abstract: An improved process for producing meta-phenoxy benzoic acids and their lower alkyl esters in improved yields and with higher selectivity by reacting an alkali metal phenate with a lower alkyl ester of meta-halobenzoic acid in the presence of a copper sulfate catalyst.Type: GrantFiled: May 14, 1980Date of Patent: February 2, 1982Assignee: Rhone-Poulenc Inc.Inventors: Fred G. Schreiber, Peter S. Gradeff
-
Patent number: 4304924Abstract: The compound, cyclopropylmethyl 4-(2-cyclopropylcarbonyloxyethoxy)benzoate, novel intermediates therefor, synthesis thereof, and the use of said compound for the control of pests.Type: GrantFiled: July 7, 1980Date of Patent: December 8, 1981Assignee: Zoecon CorporationInventors: Olive A. Henrick, Gerardus B. Staal
-
Patent number: 4288386Abstract: The Ullman reaction for the preparation of diaryl ethers by coupling aryl halides with metal phenolates is conducted in the presence of at least one tertiary amine sequestering agent having the formula:N--CHR.sub.1 --CHR.sub.2 --O--CHR.sub.3 --CHR.sub.4 --O--.sub.n R.sub.5 ].sub.Type: GrantFiled: May 12, 1980Date of Patent: September 8, 1981Assignee: Rhone-Poulenc IndustriesInventors: Gerard Soula, Louis Linguenheld
-
Patent number: 4287125Abstract: Benzenoid ethers/thioethers are prepared by reacting an activated halobenzene with an anionic reactant, RA.sup.- M.sup.+, in the presence of at least one tertiary amine sequestering agent having formula:N--CHR.sub.1 --CHR.sub.2 --O--CHR.sub.3 --CHR.sub.4 --O--.sub.n R.sub.5 ].sub.Type: GrantFiled: June 20, 1980Date of Patent: September 1, 1981Assignee: Rhone-Poulenc IndustriesInventor: Gerard Soula
-
Patent number: 4283420Abstract: The chemical compounds of the invention are useful as the active compound in drugs because of their anticonvulsant and/or antianoxic activity. They have the general formula ##STR1## wherein Z is a hydroxyl group; a group--OM wherein M is an alkali metal atom or an equivalent atom fraction of an alkaline-earth metal or an amino group such as --NH.sub.2, and R is a linear or branched alkyl group containing from 1 to 9 carbon atoms, and optionally substituted by one or more halogen atoms; a linear or branched alkenyl or alkynyl, alkoxyalkyl, or acylalkyl group containing from 2 to 9 carbon atoms and optionally substituted by one or more halogen atoms; an aryl or arylalkyl or aryloxyalkyl group comprising at least one aromatic radical and an alkyl chain having from 1 to 4 carbon atoms.Type: GrantFiled: April 18, 1979Date of Patent: August 11, 1981Assignee: LabazInventors: Charles Pigerol, Jean-Claude Vernieres, Pierre Eymard, Jacques Simiand, Madeleine Broll, Jean-Yves Lacolle
-
Patent number: 4258207Abstract: Compounds of the formula ##STR1## wherein R.sup.1 is an acyl group or certain optionally halo-substituted hydrocarbyl groups, and X is --CH.sub.2 CH(OCH.sub.3).sub.2, --CH.sub.2 CHO, --CH.dbd.CHOR.sup.2 in which R.sup.2 is acyl, --CHO, --C(O)Cl, --C(O)Br or --C(O)OR in which R is H, a salt-forming cation, an alkyl group or the residue of a pyrethroid alcohol are new pesticides or intermediates therefore. The compounds are prepared using a multi-step synthesis starting from the natural terpene, 3-carene.Type: GrantFiled: March 15, 1979Date of Patent: March 24, 1981Assignee: Shell Oil CompanyInventor: Steven A. Roman
-
Patent number: 4255313Abstract: The products of the invention are end-capped polyimide oligomers prepared from a dianhydride of an aromatic tetracarboxylic acid such as 3,3'4',4'-benzophenonetetracarboxylic acid, an aromatic diamine, and a 1-(aminoaryl)-3-hydroxy-3-methyl-1-butyne. The structure of the polyimide oligomers is shown in FIG. 3.Type: GrantFiled: April 20, 1979Date of Patent: March 10, 1981Assignee: Gulf Oil CorporationInventors: Patricia A. Antonoplos, William J. Heilman
-
Patent number: 4251417Abstract: The products of the invention are acetylene end-capped polyimide oligomers prepared from a dianhydride of an aromatic tetracarboxylic acid such as 3,3',4,4' benzophenonetetracarboxylic acid, an aromatic triamine, and an acetylene-substituted aromatic monoamine. The structure of the polyimide oligomers is shown in FIG. 3.Type: GrantFiled: April 25, 1979Date of Patent: February 17, 1981Assignee: Gulf Oil CorporationInventors: Wai Y. Chow, William J. Heilman
-
Patent number: 4251419Abstract: The products of the invention are vinyl end-capped oligomers which have the structure as shown in FIG. 3. The products are prepared from either of two (2) precursors. The first precursor is a compound which has the structure as shown in FIG. 2. The second precursor is a complex amine salt which has the structure shown in FIG. 5.Type: GrantFiled: April 5, 1979Date of Patent: February 17, 1981Assignee: Gulf Oil CorporationInventors: William J. Heilman, Daniel J. Hurley
-
Patent number: 4251420Abstract: The products of the invention are end-capped polyimide oligomers prepared from a dianhydride of an aromatic tetracarboxylic acid such as 3,3'4,4'-benzophenonetetracarboxylic acid, an aromatic triamine, and a 1-(aminoaryl)-3-hydroxy-3-methyl-1-butyne. The structure of the polyimide oligomers is shown in FIG. 3.Type: GrantFiled: April 23, 1979Date of Patent: February 17, 1981Assignee: Gulf Oil CorporationInventors: Patricia A. Antonoplos, William J. Heilman
-
Patent number: 4249015Abstract: Carboxylic acids and/or esters are prepared by converting the ##STR1## moiety in a 1-substituted 2,2-trihaloethanol, or derivative wherein X represents halogen and R is hydrogen or an acyl group to an organic acid and/or ester grouping of the formula ##STR2## wherein R' is hydrogen or alkyl of 1 to 6 carbon atoms, in the process which comprises reacting the 1-substituted 2,2,2-trihaloethanol or acylated derivative with molecular oxygen in the presence of a catalyst comprising a complex of a transition metal having an atomic number from 21-30, 39-48 or 57-80 and at least one molecule of a ligand containing trivalent nitrogen, phosphorus, arsenic or antimony. This reaction is carried out in a reaction medium comprising an alcohol or aqueous alcohol having 1 to 6 carbon atoms optionally containing an alkali metal, said alcoholic solvent also serving as a reactant source when carboxylic acid esters are formed.Type: GrantFiled: January 26, 1979Date of Patent: February 3, 1981Assignee: Shell Oil CompanyInventors: John A. Schofield, John E. Hawes
-
Patent number: 4227019Abstract: 11-Substituted prostaglandins E.sub.1, E.sub.2 and F.sub.2.alpha. useful as cardiovascular agents and as agents for inducing labor in pregnant females and for the termination of pregnancy and a process for preparing these prostaglandins.Type: GrantFiled: April 2, 1979Date of Patent: October 7, 1980Assignee: Hoffmann-La Roche Inc.Inventors: George W. Holland, Jane L. Jernow, Perry Rosen
-
Patent number: 4220753Abstract: Alkyl alkoxymethylbenzoates and essentially linear polyester ethers and copolyester ethers therefrom.Type: GrantFiled: December 18, 1978Date of Patent: September 2, 1980Assignee: Standard Oil Company (Indiana)Inventors: Steven A. Cerefice, Edward E. Paschke
-
Patent number: 4208205Abstract: Herbicidal compounds of the formula: ##STR1## where X is oxygen or sulfur;R.sub.1 is methyl or ethyl;R.sub.2 is alkyl of 1-4 carbon atoms, methoxy or cyanomethyl; andR.sub.1 and R.sub.2 together can be (CH.sub.2).sub.4 ; provided that when R.sub.2 is alkyl of 3 or 4 carbon atoms, methoxy or cyanomethyl, R.sub.1 cannot be ethyl.Type: GrantFiled: October 3, 1977Date of Patent: June 17, 1980Assignee: E. I. Du Pont de Nemours and CompanyInventor: Maged M. Fawzi
-
Patent number: 4175209Abstract: A process, and intermediates for the preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid are described. The acid possesses antiinflammatory and analgesic activity.Type: GrantFiled: September 5, 1978Date of Patent: November 20, 1979Assignee: American Hoechst CorporationInventors: Arthur R. McFadden, Richard C. Allen, Thomas B. K. Lee
-
Patent number: 4158011Abstract: A compound which is useful as one component of liquid crystal composition having superior practical properties and positive dielectric anisotropy is provided. Said compound is p'-cyanophenyl ester of p-(.beta.-alkoxy)ethoxybenzoic acid represented by the general formula ##STR1## wherein R is a straight chain alkyl group having 1 - 6 carbon atoms.Type: GrantFiled: November 9, 1977Date of Patent: June 12, 1979Assignee: Chisso CorporationInventors: Takashi Inukai, Hideo Sato
-
Patent number: 4154850Abstract: A class of di-(substituted phenoxy) alkanes having from 7 to 25 carbon atoms in the alkane moiety have hypolipidaemic activity.Type: GrantFiled: August 4, 1977Date of Patent: May 15, 1979Assignee: Beecham Group LimitedInventors: Brian Morgan, Keith H. Baggaley, Richard M. Hindley
-
Patent number: 4128574Abstract: A method is described for making organic polycarboxylic acids or anhydrides, such as aromatic ether bis(phthalic acid)s, based on a cyclic imide-cyclic anhydride exchange reaction at elevated temperatures in the presence of water. In addition to making organic polycarboxylic acid, organic imides are also generated.Type: GrantFiled: October 4, 1976Date of Patent: December 5, 1978Assignee: General Electric CompanyInventors: Ronald L. Markezich, Tohru Takekoshi