Abstract: A process, and intermediates for the preparation of 6,11-dihydro-11-oxodibenz[b,e]oxepin-2-acetic acid are described. The acid possesses antiinflammatory and analgesic activity.

Abstract: A method is provided for converting aromatic bis(ether N-organo substituted phthalimide) to aromatic bis(ether anhydride) by heating an aqueous mixture under pressure, of aromatic bis (ether N-organo substituted phthalimide) and phthalic anhydride, or phthalic acid. An exchange is effected between phthalic anhydride or phthalic acid and the aromatic bis(ether N-organo substituted phthalimide) to produce a liquid phase mixture of aromatic bis(ether phthalic acid) and an aqueous vapor phase mixture of N-organo substituted phthalimide. The N-organo substituted phthalimide is selectively removed from the liquid phase mixture by venting the vapor phase therefrom.

Abstract: A process for producing optically active 16-substituted prostaglandins and new 16-substituted prostaglandins produced thereby which are useful as cardiovascular agents and as agents for inducing labor in pregnant females and for the termination of pregnancy.