Cyanamides (i.e., Compounds Containing Cyano Bonded Directly To Amino Nitrogen) Patents (Class 564/103)
  • Patent number: 8796175
    Abstract: The invention relates to the use of at least one compound selected from the class of the sulphoximines for enhancing plants' intrinsic defenses and/or for improving plant growth and/or for enhancing the resistance of plants to plant diseases which are caused by fungi, bacteria, viruses, MLOs (mycoplasma-like organisms) and/or RLOs (rickettsia-like organisms), and/or for enhancing the resistance of plants to abiotic stress factors.
    Type: Grant
    Filed: August 17, 2009
    Date of Patent: August 5, 2014
    Assignee: Bayer CropScience AG
    Inventors: Peter Jeschke, Wolfgang Thielert, Heike Hungenberg
  • Patent number: 8692005
    Abstract: Provided are methods for decreasing the reaction time between an alkanolamine such as triethanolamine and a fatty acid alkyl ester such as, a triglyceride, a vegetable oil, a methyl ester, an ethyl ester, etc., a fatty acid, or a mixture thereof. The methods utilize a divalent zinc catalyst to facilitate and accelerate an esterification or transesterification reaction between the alkanolamine and the fatty acid, or fatty acid alkyl ester.
    Type: Grant
    Filed: August 15, 2012
    Date of Patent: April 8, 2014
    Assignee: Stepan Company
    Inventors: Marshall J. Nepras, Franz J. Luxem, Leonard F. Zaporowski, David Eisenberg
  • Publication number: 20080175780
    Abstract: The disclosure relates to a material for reversibly storing and releasing hydrogen comprising graphite or a graphitic structure, for example, comprising an ordered graphite structure of carbon and nitrogen atoms wherein the interlayer and/or interstitial volume is occupied with at least one intercalated anionic species. While any suitable anionic species can be employed, examples of suitable species are at least one of: F? (fluoride), (C?C)2? (diacetylide), and (N?C?N)2?. Desirable anionic species typically have a relatively high charge to volume ratio. The disclosure also relates to a material for reversibly storing and releasing hydrogen comprising ordered graphitic structures comprising at least one member selected from the group of graphite, single walled carbon nanotubes, multiwalled carbon nanotubes, graphite nanofibers, carbon nanohorns, and boron nitride.
    Type: Application
    Filed: January 17, 2008
    Publication date: July 24, 2008
    Applicant: AIR PRODUCTS AND CHEMICALS, INC.
    Inventors: Guido Peter Pez, Hansong Cheng, Alan Charles Cooper, Maw Lin Foo
  • Patent number: 6911559
    Abstract: A process is described for preparing sodium dicyanamide, in which cyanamide is reacted simultaneously with sodium hydroxide solution and cyanogen chloride in aqueous solution at temperatures of 20 to 100° and a pH of 7.0 to 10.0. By means of the inventive process it is possible, starting from raw materials which are available in technical-grade quality, to prepare sodium dicyanamide in good yields of 75 to 95% and very high purities of up to 100% in a very environmentally friendly manner, for which reason this process is particularly highly suitable for the industrial scale.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: June 28, 2005
    Assignee: Degussa AG
    Inventors: Franz Thalhammer, Helmut Tautz
  • Patent number: 6909014
    Abstract: The present invention relates to novel ether compounds, compositions comprising ether compounds, and methods useful for treating and preventing cardiovascular diseases, dyslipidemias, dysproteinemias, and glucose metabolism disorders comprising administering a composition comprising an ether compound. The compounds, compositions, and methods of the invention are also useful for treating and preventing Alzheimer's Disease, Syndrome X, peroxisome proliferator activated receptor-related disorders, septicemia, thrombotic disorders, obesity, pancreatitis, hypertension, renal disease, cancer, inflammation, and impotence. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.
    Type: Grant
    Filed: September 5, 2003
    Date of Patent: June 21, 2005
    Assignee: Esperion Therapeutics, Inc.
    Inventors: Jean-Louis Henri Dasseux, Carmen Daniela Oniciu
  • Patent number: 6878706
    Abstract: Compounds according to the following formula (I): wherein the variables Q and R1 to R6 are as described herein, which reversibly inhibit the cysteine proteases, such as cathepsins K, S, F, L and B; pharmaceutical compositions containing such compounds, and method of treating diseases and pathological conditions exacerbated by these cysteine proteases such as, but not limited to rheumatoid arthritis, multiple sclerosis and other autoimmune diseases, osteoporosis, asthma, Alzheimer's disease, atherosclerosis and endometriosis.
    Type: Grant
    Filed: March 27, 2003
    Date of Patent: April 12, 2005
    Assignee: Boehringer Ingelheim Pharmaceuticals Inc.
    Inventors: Thomas A. Gilmore, Eugene Richard Hickey, Weimin Liu, Peter Allen Nemoto, Denice M. Spero
  • Patent number: 6806292
    Abstract: The present invention relates to novel substituted imide derivatives of the general formula (I) in which R1 represents optionally substituted cycloalkyl, R2 represents optionally substituted alkyl or optionally substituted cycloalkyl, R3 represents alkyl, alkoxy, alkylthio, amino, alkylamino or dialkylamino and R4 represents cyano or nitro, and to processes for their preparation and to their use for controlling animal pests and as herbicides.
    Type: Grant
    Filed: July 26, 2002
    Date of Patent: October 19, 2004
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Jochem Riebel, Stefan Herrmann, Achim Hense, Ernst-Rudolf Gesing, Kristian Kather, Stefan Lehr, Wolfram Andersch, Mark Wilhelm Drewes, Dieter Feucht, Achim Harder
  • Patent number: 6683151
    Abstract: The invention relates to a compound comprising a reaction product of (A) an isocyanate functional compound of which at least 40 wt. %, relative to the total amount of (A), has a molecular weight of at least about 500, and (B) a nitrogen-containing compound capable of reacting with said isocyanate functional compound (A). The reaction product has a molecular weight of less then about 20,000 and comprises an effective amount of groups that are able to form reversible intermolecular physical interactions such that a resulting compound shows polymeric mechanical properties at a temperature below a transition temperature. The nitrogen-containing compound is, for instance, melamine, urea, acetoguanamine, benzoguanamine, cyanamide, dicyanamide, thiourea, isocytosine, pyrimidone or aminopyridine. The supramolecular compound comprising a suitable amount of the reaction products exhibits a relatively high elongation at break.
    Type: Grant
    Filed: February 24, 2000
    Date of Patent: January 27, 2004
    Assignee: DSM N.V.
    Inventors: Jacobus A. Loontjens, Johan E. G. A. Jansen, Bartholomeus J. M. Plum
  • Patent number: 6638979
    Abstract: The present invention relates to novel imidamide derivatives of the formula (I) in which R, R1, R2 and R3 are each as defined in the description, to a process for their preparation and to their use for controlling animal pests, such as insects, arachnids and, in particular, nematodes.
    Type: Grant
    Filed: February 5, 2001
    Date of Patent: October 28, 2003
    Assignee: Bayer Aktiengesellschaft
    Inventors: Hans-Jochem Riebel, Peter Gerdes, Ernst-Rudolf F. Gesing, Achim Hense, Johannes Kanellakopulos, Kristian Kather, Rolf Kirsten, Stefan Lehr, Lothar Rohe, Katharina Voigt, Detleff Wollweber, Wolfram Andersch
  • Publication number: 20030149104
    Abstract: The present invention relates to certain tri-substituted phenyl derivatives and analogues of formula (I), to a process for preparing such compounds, having the utility in clinical conditions associated with insulin resistance, to methods for their therapeutic use and to pharmaceutical compositions containing them.
    Type: Application
    Filed: November 13, 2002
    Publication date: August 7, 2003
    Inventors: Maria Boije, Jonas Fagerhag, Eva-Lotte Lindstedt Alstermark, Bengt Ohlsson
  • Publication number: 20030119803
    Abstract: A compound selected from the group consisting of a compound of formula I 1
    Type: Application
    Filed: September 17, 2002
    Publication date: June 26, 2003
    Inventors: Brent Richard Stranix, Gilles Sauve, Abderrahim Bouzide, Alexandre Cote, Gervais Berube, Patrick Soucy, Yongsen Zhao, Jocelyn Yelle
  • Publication number: 20030100613
    Abstract: The present invention relates to novel substituted imide derivatives of the general formula (I) 1
    Type: Application
    Filed: July 26, 2002
    Publication date: May 29, 2003
    Inventors: Hans-Jochem Riebel, Stefan Herrmann, Achim Hense, Ernst-Rudolf Gesing, Kristian Kather, Stefan Lehr, Wolfram Andersch, Mark Wilhelm Drewes, Dieter Feucht, Achim Harder
  • Publication number: 20030092915
    Abstract: Method of producing compounds of formula 1
    Type: Application
    Filed: December 20, 2002
    Publication date: May 15, 2003
    Inventors: Gottfried Seifert, Thomas Rapold, Verena Gisin
  • Patent number: 6548567
    Abstract: The invention relates to an ionic compound corresponding to the formula [R1X1(Z1)—Q−—X2(Z2)—R2]m Mm+ in which Mm+ is a cation of valency m, each of the groups Xi is S═Z3, S═Z4, P—R3 or P—R4; Q is N, CR5, CCN or CSO2R5, each of the groups Zi is ═O, ═NC≡N, ═C(C≡N)2, ═NS(═Z)2R6 or ═C[S(═Z)2R6]2, each of the groups Ri, is Y, YO—, YS—, Y2N— or F, Y represents a monovalent organic radical or alternatively Y is a repeating unit of a polymeric frame. The compounds are useful for producing ion conducting materials or electrolytes, as catalysts and for doping polymers.
    Type: Grant
    Filed: August 17, 2001
    Date of Patent: April 15, 2003
    Inventors: Michel Armand, Christophe Michot, Yurii Yagupolskii, Lev Yagupolskii, Andrej Bezdudny, Natalya Kondratenko
  • Patent number: 6194464
    Abstract: The present invention relates to new imidic acid derivatives of the formula (I) to a plurality of processes for their preparation, and to their use as pesticides.
    Type: Grant
    Filed: April 28, 1999
    Date of Patent: February 27, 2001
    Assignee: Bayer Aktiengesellschaft
    Inventors: Dietmar Kuhnt, Ulrich Heinemann, Herbert Gayer, Peter Gerdes, Jörg Stetter, Ralf Tiemann, Klaus Stenzel, Stefan Dutzmann
  • Patent number: 5047575
    Abstract: Compounds, and a process for their preparation, have the formula ##STR1## or corresponding salts thereof wherein R represents a group of the formula ##STR2## wherein R.sub.1 represents oxazolinyl, --C.tbd.N, --CH.sub.2 OR.sub.2 or ##STR3## These compounds in the form of pharmaceutical or cosmetic compositions are useful for the treatment of keratinization disorders.
    Type: Grant
    Filed: October 14, 1988
    Date of Patent: September 10, 1991
    Assignee: L'Oreal
    Inventors: Guy Solladie, Serge Forestier, Gerard Lang
  • Patent number: 4956503
    Abstract: A process for the preparation of N-cyanoethanimidic acid esters by reacting orthoacetic acid esters with cyanamide. The reaction is carried out in alcoholic solution in the presence of an acid catalyst. N-cyanoethanimidic acid esters can be prepared in this manner in a high yield and high state of purity, with a low technical outlay and in an environmentally safe manner, free of dangerous by-products.
    Type: Grant
    Filed: April 18, 1989
    Date of Patent: September 11, 1990
    Assignee: SKW Trostberg Aktiengesellschaft
    Inventors: Stefan Weiss, Helmut Krommer, Karl-Heinz Neuhauser
  • Patent number: 4940816
    Abstract: Acylated cyanamide compounds useful for ethanol deterrence of the formula RCONHCN, wherein R is a lipophilic acyl group or is derived from an (N-substituted)-alpha-aminoacyl group.
    Type: Grant
    Filed: July 19, 1989
    Date of Patent: July 10, 1990
    Assignee: Regents of the University of Minnesota
    Inventors: Herbert T. Nagasawa, Chul-Hoon Kwon
  • Patent number: 4891443
    Abstract: N,N'-dicyanocyclopropanecarbamidines useful as triazine intermediates, of the formula II ##STR1## in which M is hydrogen or an equivalent of an alkali or earthalkali ion and processes for their production.
    Type: Grant
    Filed: July 20, 1988
    Date of Patent: January 2, 1990
    Assignee: Ciba-Geigy Corporation
    Inventor: Henry Szczepanski
  • Patent number: 4871756
    Abstract: Compounds having the formula: ##STR1## are antagonists of leukotrienes of C.sub.4, D.sub.4, E.sub.4 and the slow reacting substance of anaphylaxis.As such, these compounds will be useful as anti-asthmatic, anti-allergic, anti-inflammatory and cytoprotective agents.
    Type: Grant
    Filed: February 17, 1987
    Date of Patent: October 3, 1989
    Assignee: Merck Frosst Canada, Inc.
    Inventors: John Gillard, Joshua Rokach, Patrice C. Belanger
  • Patent number: 4870056
    Abstract: Acylated cyanamide compounds useful for ethanol deterrence of the formula RCONHCN, wherein R is a lipophilic acyl group or is derived from an (N-substituted)-alpha-aminoacyl group.
    Type: Grant
    Filed: October 21, 1987
    Date of Patent: September 26, 1989
    Assignee: Regents of the University of Minnesota
    Inventors: Herbert T. Nagasawa, Chul-Hoon Kwon
  • Patent number: 4791229
    Abstract: A process for the preparation of an aryl cyanamide comprising reacting an arylamine of the formula ##STR1## in which Ar is aryl,R is hydrogen or alkyl, andn is 1, 2 or 3,(excepting 2-nitroaniline, 4-nitroaniline and arylamines having a nucleophilic character equal to or lower than 2-nitroaniline and 4-nitroaniline), with cyanogen chloride in 1-2 times the molar amount per mole of amino group of the arylamine initially in a homogeneous liquid phase using as reaction medium acetic acid (which is optionally diluted with water and/or a water-miscible, organic auxiliary solvent) in the presence of 1-1.5 molar equivalents of an auxiliary base for each amino group of the arylamine, there being more cyanogen chloride than equivalents of auxiliary base present in the reaction mixture at any point in time of the reaction, the pH of the reaction mixture being maintained below 7.
    Type: Grant
    Filed: October 24, 1986
    Date of Patent: December 13, 1988
    Assignee: Bayer Aktiengesellschaft
    Inventors: Rudolf Fauss, Hans-Jochem Riebel
  • Patent number: 4721770
    Abstract: N-Cyanocarboxylic acid amide derivatives which contain two or three ##STR1## groupings in the molecule are useful as hardeners for epoxide resins.
    Type: Grant
    Filed: June 24, 1986
    Date of Patent: January 26, 1988
    Assignee: Ciba-Geigy Corporation
    Inventors: Friedrich Stockinger, Friedrich Lohse, Roland Moser
  • Patent number: 4625061
    Abstract: An improved process for the preparation of cyanamide or a cyanamide-containing gas mixture by passing urea and/or urea decomposition products over a catalyst at a temperature in the range of between about 200.degree. C. and 600.degree. C. A porous catalyst is utilized which has an intracrystalline pore diameter of at most 8 A, whereby a high conversion to cyanamide is obtained and the formation of melamine by-products is substantially reduced.
    Type: Grant
    Filed: March 6, 1985
    Date of Patent: November 25, 1986
    Assignee: Stamicarbon B.V.
    Inventors: Rudolf van Hardeveld, Theodorus J. van de Mond, Franciscus H. A. M. J. Vandenbooren
  • Patent number: 4618712
    Abstract: N-Cyanocarboxlic acid amide derivatives which contain two or three ##STR1## groupings in the molecule are obtained by reacting 1 mol of a dicyanodiamine with 2 mols of a carboxylic acid anhydride or 1 mol of a dicyandiamine salt with 2 mols of a carboxylic acid halide or 1 mol of a dihalogeno compound with 2 mols of an N-cyanocarboxylic acid amide salt, or by reacting 1 mol of a carboxylic acid dichloride or trichloride with 2 or, respectively, 3 mols of a cyanamide or 1 mol of a carboxylic acid dicyandiamide or tricyantriamide salt with 2 or 3 mols of an alkylating agent.The N-cyanocarboxylic acid amide derivatives according to the invention are useful hardeners for epoxide resins.
    Type: Grant
    Filed: February 15, 1983
    Date of Patent: October 21, 1986
    Assignee: Ciba-Geigy Corporation
    Inventors: Friedrich Stockinger, Friedrich Lohse, Roland Moser
  • Patent number: 4595782
    Abstract: The present invention is for a process for the preparation of alkali metal salts of acyl cyanamides, especially those of aliphatic carboxylic acids by reacting carboxylic acid esters of lower alcohols with monoalkali metal cyanamides. The reaction results in a process which is simple and efficient and one which can be used in commercial scale batch or continuous operations.
    Type: Grant
    Filed: November 14, 1984
    Date of Patent: June 17, 1986
    Assignee: Henkel Kommanditgesellschaft auf Aktien
    Inventors: Christian Hase, Horst Baumann, Franz-Josef Carduck, Hubert Pawelczyk
  • Patent number: 4578220
    Abstract: A novel charge transfer complex of an N,N'-biscyanoquinone bisimine of the formula ##STR1## and a fulvalene derivative of the formula ##STR2## where, in formula I, R.sup.1, R.sup.2, R.sup.3 and R.sup.4 independently of one another are --H, --CH.sub.3, --C.sub.2 H.sub.5, --OCH.sub.3, --OC.sub.2 H.sub.5, --Cl and/or --Br, and one of the radicals R.sup.1 and R.sup.2 and/or one of the radicals R.sup.3 and R.sup.4 may furthermore be phenyl or tert.-butyl, or R.sup.1 and R.sup.2 and/or R.sup.3 and R.sup.4 together form ##STR3## and the fused-on aromatic ring is unsubstituted or substituted, and, in formula (II), R.sup.5, R.sup.6, R.sup.7 and R.sup.8 independently of one another are each --H, --CH.sub.3, --C.sub.2 H.sub.5, phenyl, methylphenyl or methoxyphenyl, or R.sup.5 and R.sup.6 and/or R.sup.7 and R.sup.8 together form ##STR4## where n=3, 4 or 5, ##STR5## and X and Y indendently of one another are each S or Se.
    Type: Grant
    Filed: October 18, 1984
    Date of Patent: March 25, 1986
    Assignee: BASF Aktiengesellschaft
    Inventors: Siegfried Huenig, Alexander Aumueller
  • Patent number: 4571434
    Abstract: Oligo-imino-amines possessing plant-physiological activities and process for preparing the same are provided. Said substance is represented by the general formula. ##STR1## Wherein n=4-6.
    Type: Grant
    Filed: June 13, 1983
    Date of Patent: February 18, 1986
    Assignee: Nihon Tokusan Kabushiki Kaisha
    Inventors: Takeshi Hashizume, Hiroshi Onoda
  • Patent number: 4550203
    Abstract: N-substituted N-cyanocarboxylic acid amides are prepared by reacting 1 mol of an N-cyanocarboxylic acid amide salt with 1 mol of an alkyl halide or an alkylating agent, for example dimethyl sulfate or diethyl sulfate, in a polar aprotic solvent.The N-substituted N-cyanocarboxylic acid amides which can be obtained by the process according to the invention are useful curing agents for epoxide resins.
    Type: Grant
    Filed: February 15, 1983
    Date of Patent: October 29, 1985
    Assignee: Ciba Geigy Corporation
    Inventors: Friedrich Stockinger, Friedrich Lohse, Helmut Zondler
  • Patent number: 4543352
    Abstract: A class of naphthalene aminoalkylene ether and thioether compounds exhibiting pharmacological activity including anti-secretory and anti-ulcerogenic activity, pharmaceutical compositions comprising these compounds, and methods for the treatment of gastrointestinal hyperacidity and ulcerogenic disorders in mammals using said compositions are disclosed.
    Type: Grant
    Filed: April 29, 1983
    Date of Patent: September 24, 1985
    Assignee: William H. Rorer, Inc.
    Inventors: Donald E. Kuhla, Henry F. Campbell, William L. Studt
  • Patent number: 4529821
    Abstract: N-Cyanoacylamide compounds of the formula I ##STR1## wherein R.sub.1 is hydrogen, alkyl, cycloalkyl or aryl, R.sub.2 is hydrogen or alkyl and R.sub.3 is hydrogen or alkyl and R.sub.3 is alkylene or arylenealkylene, are prepared by reacting 1 mol of an N-cyanocarboxylic acid amide salt with 1 mol of a halogen compound in a polar, aprotic solvent.The N-cyanoacylamide compounds of the formula I can be used for hardening epoxide resins, for the preparation of isomelamine or for the preparation of linear polymers which can be crosslinked by heat.
    Type: Grant
    Filed: February 15, 1983
    Date of Patent: July 16, 1985
    Assignee: Ciba-Geigy Corporation
    Inventors: Friedrich Stockinger, Friedrich Lohse, Roland Moser
  • Patent number: 4465825
    Abstract: This invention is directed to processes for forming either solid, linear polymers or thermoset polymers from novel N-cyanourea compounds of the formula: ##STR1## wherein n is at least 2 and R is the organic moiety of a polyisocyanate remaining after reacting the NCO groups of the polyisocyanate with cyanamide, preferably under atmospheric conditions. These N-cyanourea compounds are polymerized to solid, linear polymers useful as an epoxy curing agent, by agitation for about 50 hours under atmospheric conditions or to a thermoset polymer useful per se as an adhesive or sealant by heating at a temperature above 90.degree. C.
    Type: Grant
    Filed: December 18, 1981
    Date of Patent: August 14, 1984
    Assignee: W. R. Grace & Co.
    Inventor: Shiow-Ching Lin
  • Patent number: 4389219
    Abstract: Mixture of a fuel oil and pulverized coal are stabilized by the addition of a small amount of a polyether-type adduct having a molecular weight of from 6,000 to 600,000 between a lower alkylene oxide and a poly(lower alkyleneimine) compound, or a derivative of said adduct.
    Type: Grant
    Filed: February 23, 1982
    Date of Patent: June 21, 1983
    Assignee: Dai-Ichi Kogyo Seiyaku Co., Ltd.
    Inventors: Akihiro Naka, Shuichi Honjo
  • Patent number: 4314081
    Abstract: 3-Aryloxy-3-phenylpropylamines and acid additions salts thereof, useful as psychotropic agents, particularly as anti-depressants.
    Type: Grant
    Filed: January 10, 1974
    Date of Patent: February 2, 1982
    Assignee: Eli Lilly and Company
    Inventors: Bryan B. Molloy, Klaus K. Schmiegel
  • Patent number: 4265907
    Abstract: Insecticidal compounds having the formula: ##STR1## wherein R is halogen (Cl, F, Br), C.sub.1 -C.sub.4 alkyl, NO.sub.2, C.sub.1 -C.sub.4 alkoxy, C.sub.1 -C.sub.4 alkylthio, cyano, CF.sub.3, CF.sub.3 O, CF.sub.3 S, ClF.sub.2, CHF.sub.2 O, or CHF.sub.2 S; n is 0, 1, or 2; R.sub.1 is C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.6 cycloalkyl, or C.sub.2 -C.sub.4 alkenyl; and R.sup.2 is hydrogen, cyano, formyl, C.sub.1 -C.sub.4 acyl, C.sub.1 -C.sub.4 carboalkoxy, carbamoyl, N-C.sub.1 -C.sub.4 alkylcarbamoyl, or N,N-di C.sub.1 -C.sub.4 alkylcarbamoyl.
    Type: Grant
    Filed: December 31, 1979
    Date of Patent: May 5, 1981
    Assignee: Mobil Oil Corporation
    Inventor: Jill H. Paul