Abstract: The present disclosure provides a catheter comprising one or more infusion lumens each terminating at an infusion eye, and one or more sensor lumens each terminating at a sensor eye. The present disclosure also provides a sheath introducer comprising one or more sensor lumens each terminating at a sensor eye, and an introducer lumen terminating at an introducer eye.

Abstract: Disclosed herein is implantable device with a layer of dehydrated basement membrane formed thereon, the implantable device comprising at least one member selected from the group consisting of cannulas, collars for cannulas, and collars for sensors. Methods of making and using the extended use device also are disclosed.

Abstract: Described are methods and systems to allow the use of a very simple physiological meter without a user input interface (i.e., buttonless) while maintaining the ability to store time linked measurement records for retrospective or prospective analysis of the measured physiological measurements.

Abstract: Some embodiments provide a system for synchronizing and configuring monitoring devices. In some embodiments, a patient monitoring device settings module is configured to automatically provide configuration settings to a plurality of patient monitoring devices. A monitoring device data module is configured to receive measurement data from at least one of the patient monitoring devices. An electronic medical records system interface is configured to provide patient data at least partially derived from the received measurement data to an electronic medical records system. A patient records interface is configured to provide patient data to at least one of the patient monitoring devices.

Abstract: Methods, device and systems including receiving a request for a therapy profile for treating a medical condition, determining using a processor a plurality of therapy profile parameters, assigning a weighted value to each therapy profile parameter based on a hierarchy determined by the medical condition, querying a database to identify a stored therapy profile with therapy profile parameters that most closely correspond to the determined plurality of therapy profile parameters based on the hierarchy, generating an output data corresponding to the identified stored therapy profile, the output data a medication dosage information are provided. Also provided are systems and kits.

Abstract: A blood glucose and lifestyle tracking apparatus is disclosed. The blood glucose and lifestyle tracking apparatus provides a method for recording both blood glucose values for fasting, postprandial, and preprandial time periods and lifestyle factors.

Abstract: Methods and apparatus for providing data processing and control for use in verifying the stability of sensor sensitivity of an analyte sensor.

Abstract: A finger guide for testing blood glucose and associated methods are disclosed. More particularly, a blood glucose testing system is provided that includes a finger guide that is wearable by the subject of the blood glucose test and a glucose meter that is retrofitted with a glucose meter coupler. A method of operating the blood glucose testing system includes the steps of guiding a lancing device to a spot on the subject's finger for producing a blood droplet and guiding a test strip in the glucose meter to the same spot on the subject's finger for testing the blood sample.

Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

Abstract: The present disclosure provides a sensor port configured to receive a plurality of analyte sensors having different sizes, shapes and/or electrode configurations. Also provided are analyte meters, analyte monitoring devices and/or systems and drug delivery devices and/or systems utilizing the disclosed sensor ports.

Abstract: A health monitoring and diagnostic device (LIFESTREAM cholesterol meter) configured as a self-contained testing and diagnostic unit in a clam-shell type case. One side of the case includes a spring-loaded finger stick and a compartment for carrying one or more packages of disposable items including a test strip, a needle for the finger stick, and an alcohol swipe. The other half of the case includes a test strip reader, a key pad, and a liquid crystal display. The meter reads a test strip carrying a droplet of blood and receives additional diagnostic information from the patient, such as age, gender, weight, and family history of heart disease. Within minutes, the meter displays test results, including total cholesterol levels. The meter also displays additional diagnostic results, such as the patient's “cardiac age,” recommended weight loss, and a cardiac risk assessment. The meter also works in connection with a network-based comprehensive health analysis and reporting system.

Abstract: A tape cassette for a medical handheld device is disclosed as comprising a carrier tape, which carries test fields for assaying a sample of a human or animal bodily fluid and/or lancets as functional elements, a supply chamber, in which a supply section of the carrier tape comprising unused functional elements is positioned, a winding unit, in order to wind up the carrier tape and draw it through a tape exit opening of the chamber, so that the functional elements may be brought sequentially into a usage position. The carrier tape in the tape exit opening is oriented transversely to the supply section positioned in the supply chamber.

Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.

Abstract: A portable unit comprises a sampling mechanism used by a patient to take a sample of a bodily fluid or tissue that can be tested for any property indicative of a medical condition of the patient, a microprocessor for determining a treatment for the condition based on a test of the sample, and an administration mechanism for administering the treatment based on the determination by the microprocessor. Operationally, the unit samples a bodily function, evaluates the sample, determines from stored protocols and criteria if treatment is required, and administers treatment.

Abstract: A system for medical diagnosis, monitoring, and treatment is described, including a medical band comprising one or more sensors configured to gather data associated with at least one symptom of a medical condition, a memory configured to store the data and an application, the application being configured to determine the medical condition using the data, a processor configured to execute the application, and a notification facility configured to provide a notification upon receiving from the application an instruction associated with the notification, wherein the notification is associated with a diet.

Abstract: Methods and devices to detect analyte in body fluid are provided. Embodiments include positioning an analyte sensor in fluid contact with an analyte, detecting an attenuation in a signal from an analyte sensor after positioning during a predetermined time period, categorizing the detected attenuation in the analyte sensor signal based, at least in part, on one or more characteristics of the signal, performing signal processing to generate a reportable data associated with the detected analyte sensor signal during the predetermined time period, managing if and when to request additional reference signal measurements, and managing if and when to temporarily not display results.

Abstract: A platform has microneedles for determining blood levels of compound of interest, such as glucose.

Abstract: A health care medical device includes one or more medical sensor devices, an assembly that houses the one or more medical sensor devices and a mobile electronic computing device with a display. The mobile electronic computing device is secured to the assembly. Medical data from the one or more medical sensor devices is transmitted to the mobile electronic computing device.

Abstract: Method and system for providing diabetes management and insulin therapy based on substantially real time glucose monitoring system is provided.

Abstract: The present invention provides a blood parameter sensing system that may include a sensor, a blood access system, a flow controller and a monitor system. The blood access system may include a blood draw member having an internal configuration adapted to avoid clotting without the use of anticoagulants and under a range of flow profiles, including small volume blood draws. The flow controller may be configured to adapt to a range of access devices by using feedback from the sensor and monitor to customize flow profiles. The monitor system is configured to reduce parameter measurement error by modeling sensitivity change during system startup or reconnect.

Abstract: Methods, system and devices for providing improved calibration accuracy of continuous glucose monitoring system based on insulin delivery information are provided.

Abstract: Methods, system and devices for monitoring control parameters in a closed loop control operation including continuously monitoring glucose level and automatic administration of a medication, detecting a condition associated with hypoglycemia, determining whether a probability of the detected condition associated with hypoglycemia exceeding a threshold level, and outputting a notification based upon the determination are provided.

Abstract: Transdermal analyte monitoring systems (TAMS) having increased longevity and improved analyte detection are described herein. Kits for use with the TAMS and methods of using the TAMS and kits are also described. In a preferred embodiment, the TAMS includes a protective, semi-permeable membrane covering the surface of the hydrogel. The protective, semi-permeable membrane contacts with the skin of a user and prevents contamination or fouling of the hydrogel. Optionally, the hydrogel comprises one or more humectants and/or an immobilized enzyme. In another preferred embodiment, the TAMS contains at least one channel or pocket for increasing the amount of oxygen provided to the hydrogel. In one embodiment, a method for improving analyte detection by the TAMS is provided. For example, after the skin porosity is increased by an appropriate pretreatment, a skin preparation wipe is applied to the treated skin area and then the TAMS is applied to the treated area.

Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.

Abstract: The present invention relates generally to variable stiffness transcutaneous medical devices including a distal portion designed to be more flexible than a proximal portion. The variable stiffness can be provided by a variable pitch in one or more wires of the device, a variable cross-section in one or more wires of the device, and/or a variable hardening and/or softening in one or more wires of the device.

Abstract: Systems and methods for dynamically and intelligently estimating analyte data from a continuous analyte sensor, including receiving a data stream, selecting one of a plurality of algorithms, and employing the selected algorithm to estimate analyte values. Additional data processing includes evaluating the selected estimative algorithms, analyzing a variation of the estimated analyte values based on statistical, clinical, or physiological parameters, comparing the estimated analyte values with corresponding measure analyte values, and providing output to a user. Estimation can be used to compensate for time lag, match sensor data with corresponding reference data, warn of upcoming clinical risk, replace erroneous sensor data signals, and provide more timely analyte information encourage proactive behavior and preempt clinical risk.

Abstract: In one aspect, there is provided assembling an analyte sensor with an analyte sensor insertion device, packaging the assembled analyte sensor and sensor insertion device in a substantially airtight seal, and irradiating the packaged assembled analyte sensor and sensor insertion device at a predetermined dose using one or more electron beam accelerators.

Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: Embodiments include an apparatus responsive to an event detected at a glucose monitoring device. The apparatus includes circuitry to select an action to occur remote to the glucose monitoring device in response to the event. Embodiments include a response center responsive to an event at a glucose monitoring device to contact a person in response to the event.

Abstract: A one touch laser lancing type blood glucose measurement device, a strip, and the method using it. In particular, the invention relates to a one touch laser lancing type blood glucose measurement device, a strip, and the method using it, which performs blood gathering and blood glucose measurement at the same time, using laser beams generated in a laser module. The laser beams are irradiated into a finger passing a hole of a strip with a focusing lens converging the laser beams, a protect window, and the hole to gather blood, then the blood is absorbed into the strip for measuring blood glucose.

Abstract: A region of skin, other than the fingertips, is stimulated. After stimulation, an opening is created in the skin (e.g., by lancing the skin) to cause a flow of body fluid from the region. At least a portion of this body fluid is transported to a testing device where the concentration of analyte (e.g., glucose) in the body fluid is then determined. It is found that the stimulation of the skin provides results that are generally closer to the results of measurements from the fingertips, the traditional site for obtaining body fluid for analyte testing.

Abstract: A sensing apparatus may include a substrate having a first side for a sensing element and a second side for electronics, the substrate may have a at least one via from the first side of the substrate to the second side of the substrate, the at least one via may be hermetically sealed with an optically transmissive material.

Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.

Abstract: Systems and methods of use for continuous analyte measurement of a host's vascular system are provided. In some embodiments, a continuous glucose measurement system includes a vascular access device, a sensor and sensor electronics, the system being configured for insertion into a host's peripheral vein or artery.

Abstract: The present invention relates to a non-invasive blood glucose sensor, comprising: a substrate, a first metal layer, a second metal layer, and a blood glucose sensing unit, wherein the first metal layer is formed on the one surface of the substrate and has a microstrip antenna in the internal thereof, the second metal layer is formed on the other surface of the substrate, and the blood glucose sensing unit is electrically connected to the first metal layer and the second metal layer. In the present invention, the non-invasive blood glucose sensor can be used to measure a numerical value of the blood glucose in a human body by way of disposing the non-invasive blood glucose sensor near the human body, without using any body-invading ways, for example, the acupuncture treatment; therefore the inconveniences and incorrect measurements resulting from the body-invading ways can be avoided.

Abstract: Systems and methods for minimizing or eliminating transient non-glucose related signal noise due to non-glucose rate limiting phenomenon such as ischemia, pH changes, temperatures changes, and the like. The system monitors a data stream from a glucose sensor and detects signal artifacts that have higher amplitude than electronic or diffusion-related system noise. The system replaces some or the entire data stream continually or intermittently including signal estimation methods that particularly address transient signal artifacts. The system is also capable of detecting the severity of the signal artifacts and selectively applying one or more signal estimation algorithm factors responsive to the severity of the signal artifacts, which includes selectively applying distinct sets of parameters to a signal estimation algorithm or selectively applying distinct signal estimation algorithms.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: An analyte sensor including an antiglycolytic agent or a precursor thereof and a chelating agent that stabilizes the antiglycolytic agent positioned proximate to the working electrode of the sensor. Also provided are systems and methods of using the electrochemical analyte sensors in analyte monitoring.

Abstract: The present invention relates generally to systems and methods for measuring an analyte in a host. More particularly, the present invention relates to systems and methods for transcutaneous measurement of glucose in a host.

Abstract: A glucose evaluation system operates to evaluate and display glucose data. The glucose data is evaluated and a display is generated that presents the glucose data in a form that quickly conveys key information to a caregiver, without requiring the caregiver to spend a great deal of time studying the data or the display.

Abstract: A system including a host device and a measurement device ultrasonically coupled to the host device over a physical medium and method of operating the same has been introduced herein. In one embodiment, the system includes the host device including a first ultrasonic communicator configured to generate an ultrasonic command to measure a parameter of an object, a physical medium coupled to the host device and the measurement device coupled to the physical medium. The measurement device includes a second ultrasonic communicator configured to receive the ultrasonic command via the physical medium, and a sensor configured to measure a parameter of the object in response to the ultrasonic command to provide a sensed parameter, the second ultrasonic communicator being configured to transmit the sensed parameter to the host device via the physical medium.

Abstract: Methods and systems for providing data communication in medical systems are disclosed.

Abstract: A wearable medical device (10) comprising: spectacles or eyeglasses (12) including at least one temple piece (14) and nose-engagers (16); at least one bio-sensor (18) for measuring at least one physical parameter of a person wearing said spectacles (12), said bio-sensor (18) being associated with one of said temple piece (14) or said nose-engagers (16); information storage (20) incorporated with said spectacles (12) for storing information received from said bio-sensor (18); a transmitter (22) for transmitting said stored information; and a power supply (24) for driving said bio-sensor, said storage and said transmitter.

Abstract: A blood glucose meter is provided. The blood glucose meter includes a body of the blood glucose meter, a lancing unit which is provided at one side of the body of the blood glucose meter and includes a lancet to puncture a skin in order to sample blood of a user, a sensor strip unit which is provided at another side of the body of the blood glucose meter which is different than the one side of the body at which the lancing unit is provided, the sensor strip unit being configured to sample the blood of the user, and a measurement unit which measures the blood sampled by the sensor strip unit. The blood glucose meter has the measurement unit which is integrally assembled with the body of the blood glucose meter and includes the lancing unit having the lancet and the sensor strip unit.

Abstract: An analyte monitoring system, which can be used to monitor blood sugar, is provided with a sensor which detects a plurality of blood sugar levels in blood on the basis of a sampling interval, a meal data setting unit which sets information based on meal contents, and a sampling interval setting unit which sets the sampling interval of the sensor using the information based on meal contents set by the meal data setting unit. By predicting a fluctuation curve of the blood sugar level after a meal by information based on meal contents to thereby change the sampling interval, a fluctuation state of the blood sugar level can be efficiently monitored.

Abstract: Systems and methods for processing sensor analyte data, including initiating calibration, updating calibration, evaluating clinical acceptability of reference and sensor analyte data, and evaluating the quality of sensor calibration. During initial calibration, the analyte sensor data is evaluated over a period of time to determine stability of the sensor. The sensor may be calibrated using a calibration set of one or more matched sensor and reference analyte data pairs. The calibration may be updated after evaluating the calibration set for best calibration based on inclusion criteria with newly received reference analyte data. Fail-safe mechanisms are provided based on clinical acceptability of reference and analyte data and quality of sensor calibration. Algorithms provide for optimized prospective and retrospective analysis of estimated blood analyte data from an analyte sensor.

Abstract: The present invention provides a module for a computer interface including a transducer wherein the transducer receives a measurement value and makes this measurement value available for monitoring an individual's health by means of the computer interface, for example, for monitoring an individual's blood glucose level, wherein the measurement value is obtained by means of a sensor.