Combined With Therapeutic Or Diverse Diagnostic Device Patents (Class 600/411)
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Patent number: 10548506Abstract: Systems and methods for manufacturing and using magnetic resonance (“MR”) visible labels, markers, or assemblies to encode information unique to the subject or object being imaged by a magnetic resonance imaging (“MRI”) system are provided. The use of such MR-visible labels, markers, or assemblies enables unique information associated with the subject or object being imaged to be encoded into the images of the subject or object. This information can be used to anonymize protected health information (“PHI”); to provide detailed information about a surgical simulation device, quality assurance phantom, or the like; to provide spatial orientation and registration information; or so on.Type: GrantFiled: October 14, 2016Date of Patent: February 4, 2020Assignee: SYNAPTIVE MEDICAL (BARBADOS) INC.Inventors: Gregory A. Whitton, Timotheus Gmeiner, Fergal Kerins
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Patent number: 10551456Abstract: In a method, apparatus and medical imaging system to generate image data based on magnetic resonance (MR) thermometry data, planning data of a region of an examination subject that is to be depicted thermometrically are provided to a processor. Through the processor, segmentation data based on the planning data are generated MR thermometry data are provided to the processor, which generates image data on the basis of the MR thermometry data, using the segmentation data.Type: GrantFiled: February 13, 2014Date of Patent: February 4, 2020Assignee: Siemens AktiengesellschaftInventors: Joerg Roland, Eva Rothgang, Michael Suehling
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Patent number: 10536686Abstract: An exoscope with enhanced depth of field imaging is provided. The exoscope includes first and second sets of optical devices, the first set having a fixed image plane, the second set having a variable image plane adjacent the fixed image plane of the first set. The second set includes at least one variable device configured to change the position of the variable image plane. A beamsplitter splits light from a combined optical path of the first and second set to respective image devices of the first and second set of optical devices. A controller controls the at least one variable device to change the position of the variable image plane relative to the fixed image plane, combines images acquired by the respective image devices, and controls a display device to render a combined image.Type: GrantFiled: August 2, 2018Date of Patent: January 14, 2020Assignee: SYNAPTIVE MEDICAL (BARBADOS) INC.Inventors: William La, Siu Wai Jacky Mak
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Patent number: 10517490Abstract: A method for producing an image representative of the vasculature of a subject using a MRI system includes the acquisition of a signal indicative of a subject' cardiac phase. During each heartbeat of the subject, image slices of a volume covering a region of interest (ROI) within the subject are acquired by applying a volume-selective venous suppression pulse to suppress (a) venous signal for an upper slice in the ROI; (b) venous signal for slices that are upstream for venous flow in the ROI; and (c) background signal from the upstream slices. Next, a slice-selective background suppression pulse is applied to suppress background signal of the upper slice. Following a quiescent time interval, a spectrally selective fat suppression pulse is applied to the entire volume to attenuate signal from background fat signal. Then, a simultaneous multi-slice acquisition of the upper slice and the upstream slices is performed.Type: GrantFiled: October 24, 2016Date of Patent: December 31, 2019Assignees: Siemens Healthcare GmbH, Northshore University HealthsystemInventors: Shivraman Giri, Robert R. Edelman, Ioannis Koktzoglou, Himanshu Bhat
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Patent number: 10511822Abstract: Embodiments disclose a real-time surgery method and apparatus for displaying a stereoscopic augmented view of a patient from a static or dynamic viewpoint of the surgeon, which employs real-time three-dimensional surface reconstruction for preoperative and intraoperative image registration. Stereoscopic cameras provide real-time images of the scene including the patient. A stereoscopic video display is used by the surgeon, who sees a graphical representation of the preoperative or intraoperative images blended with the video images in a stereoscopic manner through a see through display.Type: GrantFiled: July 22, 2019Date of Patent: December 17, 2019Assignee: OnPoint Medical, Inc.Inventor: Carlos Quiles Casas
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Patent number: 10506991Abstract: A method includes, receiving (i) a set of two-dimensional (2D) slices of a segmented three-dimensional (3D) anatomical image of an organ of a patient, and (ii) position signals that are indicative of respective position and orientation of a distal tip of a medical tool in the organ. An optical axis of the medical tool is estimated based on the position signals. A slice that is: (i) oriented at a predefined angle relative to the optical axis, and (ii) includes the position of the distal tip, is selected from among the slices. The selected slice is displayed to a user, together with a marker indicative of the position of the distal tip.Type: GrantFiled: August 31, 2017Date of Patent: December 17, 2019Assignee: Biosense Webster (Israel) Ltd.Inventor: Assaf Govari
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Patent number: 10495706Abstract: Combined MRI and radiotherapy installations require complex Faraday cage structure that encloses the room, the MRI magnets, and the patient volume, but excludes the linear accelerator path and its supply cabling. A problem with this is that the MRI magnets tend to vibrate when in use, and if physically connected to a rigid structure then the vibrations will be passed to that structure also. To alleviate this, we propose that the Faraday cage be made of a mix of prefabricated conductive sections and flexible sections of a conductive sheet. The flexible conductive sheet can be copper or aluminium, in the form of a foil or mesh.Type: GrantFiled: November 7, 2018Date of Patent: December 3, 2019Assignee: Elekta LimitedInventors: Jurgen Michael Mikeska, Andreas Michael Hainke
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Patent number: 10492709Abstract: Body-mountable devices are provided to detect the presence or status of an analyte in subsurface vasculature of a body by detecting fluorescent reporters that are bound to instances of the analyte in the subsurface vasculature. Such devices further operate to exert an attractive magnetic force on magnetic nanoparticle-containing probes that are configured to bind to the analyte, thus concentrating the analyte proximate the devices by magnetically exerting attractive forces on such probes that are bound to instances of the analyte. The analyte can be an extracellular vesicle that is characteristic of a cancer, and a body-mountable device as described herein could be used to detect such extracellular vesicles in a portion of subsurface vasculature such that a presence or status of a tumor could be determined based on an amount, presence, or other detected property of the extracellular vesicle.Type: GrantFiled: October 14, 2016Date of Patent: December 3, 2019Assignee: Verily Life Sciences LLCInventors: Mark Audeh, Joshua Simon Klein, Anthony M Giannetti, Stephen Morton, James Michael Higbie
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Patent number: 10495707Abstract: In beta emission imaging, magnetic lensing allows a lower resolution detector to detect the spatial distribution of emissions at a higher resolution. The sample is placed in a magnetic field with field lines at a given density, and the detector is placed away from the sample where the magnet field lines diverge, resulting in a lesser density. Since the beta emissions travel along the field lines, the divergence of the field lines from the sample to the detector result in lensing or magnification. Using positron attenuation tomography to detect annihilation in the detector allows for correction due to self-absorption by the sample. The correction and lensing are used together or may be used independently.Type: GrantFiled: May 16, 2018Date of Patent: December 3, 2019Assignee: Siemens Medical Solutions USA, Inc.Inventor: Charles C. Watson
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Patent number: 10485992Abstract: It is an object of the invention to provide for a system, method and computer program product enabling monitoring of effects of intrafraction motion during the radio therapy treatment. According to a first aspect of the invention this object is achieved by an ultrasound guided radiotherapy system, comprising a radiotherapy system configured for providing a radiation treatment by means of a radiation beam to a treatment target. The ultrasound guided radiotherapy system further comprises an ultrasound imaging system configured for acquiring a 3D online image of the treatment target and/or an organ at risk during the radiation treatment.Type: GrantFiled: June 6, 2016Date of Patent: November 26, 2019Inventors: Harald Sepp Heese, Torbjorn Vik, Heinrich Schulz, Christian Buerger, Jochen Peters
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Patent number: 10481114Abstract: A core holder for a reservoir rock core sample for MR or MRI measurement including a casing and a chamber internal to the core holder, an inlet and an outlet in the core holder for circulating a confining fluid in the chamber, a sample housing in the chamber for containing the core sample, the sample housing including an inlet and an outlet in the sample holder for circulating fluid to and from the sample, and a membrane for isolating the sample from fluid contact with the confining fluid but permitting fluid pressure to be exerted on the sample when the confining fluid is pressurized, the space in the chamber not occupied by the sample housing defining a void space, an RF probe in the void space and at least partially surrounding the sample housing, whereby confining fluid introduced into the chamber circulates in the void space around the RF probe.Type: GrantFiled: August 11, 2017Date of Patent: November 19, 2019Assignee: University of New BrunswickInventors: Mojtaba Shakerian, Bruce J. Balcom
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Patent number: 10475192Abstract: During a focused-ultrasound or other non-invasive treatment procedure, the motion of the treatment target or other object(s) of interest can be tracked in real time based on (i) the comparison of treatment images against a reference library of images that have been acquired prior to treatment for the anticipated range of motion and have been processed to identify the location of the target or other object(s) therein and (ii) complementary information associated with the stage of the target motion during treatment.Type: GrantFiled: June 10, 2016Date of Patent: November 12, 2019Assignee: INSIGHTEC, LTD.Inventor: Yoav Levy
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Patent number: 10463855Abstract: A system and a method for optimizing the configuration of multisite transcranial current stimulation, including providing an electric field characteristic target map on the brain's cortex, the target map including multiple cortical targets, the multiple cortical targets are localized and/or continuously varying and spatially extended, providing a weight map on the cortical surface prioritizing the important of areas in the target map for the purposes of optimization; and calculating, based on the target and weight maps, optimal currents and optimal locations for a plurality of electrodes intended for providing transcranial current stimulation to globally stimulate at once the multiple cortical targets with excitatory, inhibitory or neutral stimulation.Type: GrantFiled: May 16, 2017Date of Patent: November 5, 2019Assignees: NEUROELECTRICS BARCELONA S.L., BETH ISRAEL DEACONESS MEDICAL CENTERInventors: Giulio Ruffini, Oscar Ripolles Mateu, Alvaro Pascual-Leone, Michael D. Fox, Pedro Michael Cavaleiro Miranda
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Patent number: 10463880Abstract: An applicator device (100, 200, 300) for use in interventional brachytherapy, wherein the applicator device (100, 200, 300) is configured to be inserted in, or near a region of interest within a living body, and the applicator device is defining a lumen (101, 201, 301) for receiving a radiation source (103, 203, 303), characterized in that the applicator device (100, 200, 300) comprises one or more sensor elements (102, 202, 302) each configured to generate an output signal indicative of whether or not the radiation source (103, 203, 303) is at a predetermined position in the lumen (101, 201, 301).Type: GrantFiled: February 10, 2015Date of Patent: November 5, 2019Assignee: Koninklijke Philips N.V.Inventors: Guillaume Leopold Theodorus Frederik Hautvast, Dirk Binnekamp
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Patent number: 10456594Abstract: A brachytherapy method and apparatus include implanting an applicator having at least one radiation source or seed receiving channel (62) into soft tissue adjacent a target region (40) to be irradiated. A high resolution planning image (64) of the target region including the applicator is generated, wherein the high resolution planning image is used for determining a three-dimensional treatment plan (66). A position of the applicator is tracked relative to the target region (40) and the treatment plan (66). Tracking the position includes measuring, via shape-sensing, a location and shape of the at least one radiation source or seed receiving channel (62).Type: GrantFiled: November 17, 2010Date of Patent: October 29, 2019Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Laurent Verard, Luis Felipe Gutierrez, Dirk Binnekamp
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Patent number: 10448003Abstract: An intraoperative, marker-less visualization system and method for visualizing three-dimensional surface structures and depth structures of a patient during an intervention. A C-arm carries a C-arm projection module and a camera, and visualization spectacles include an HMD (head-mounted device) projection module and a camera. The projection modules serve for projecting structured light. A processor computes a combined image data set in order to project the latter onto spectacle lenses of the visualization spectacles.Type: GrantFiled: March 31, 2015Date of Patent: October 15, 2019Assignee: Siemens AktiengesellschaftInventor: Alexander Grafenberg
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Patent number: 10433929Abstract: A method for registering a catheter navigation system to a three-dimensional image generally includes obtaining a three-dimensional image including position information for a plurality of surface points on a part of a patient's body, using a catheter navigation system to place a tool at a location on the surface of the patient's body, measuring position information for the surface location, identifying a corresponding location on the image, associating position information for the surface location and the location identified on the image as a fiducial pair, and using at least one fiducial pair to generate a mapping function. The mapping function transforms points within the coordinate system of the catheter navigation to the coordinate system of the three-dimensional image such that, for each fiducial pair, the mapping error is about zero. Suitable warping algorithms include thin plate splines, mean value coordinates, and radial basis function networks.Type: GrantFiled: March 9, 2007Date of Patent: October 8, 2019Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.Inventors: Eric S. Olson, Eric J. Voth, Jeffrey A. Schweitzer
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Patent number: 10426374Abstract: The present disclosure provides methods for targeting a biomedical system. Aspects of the subject methods include determining the trajectory of a targeting device using magnetic resonance imaging (MRI) of a MRI-visible style of a trajectory guide that is compatible with the targeting device. Targeted biomedical systems may be utilized for a variety of purposes including targeted delivery of a therapeutic, holding a therapeutic device, positioning of a therapeutic device and other uses. Also provided are devices and systems that can be used in practicing the described methods including but not limited to trajectory guides and adjustable targeting systems, as well as non-transitory computer readable medium storing instructions that, when executed by a computing device, cause a computing device to perform steps of the described methods.Type: GrantFiled: July 18, 2018Date of Patent: October 1, 2019Assignee: The Regents of the University of CaliforniaInventors: Krystof S. Bankiewicz, Kathryn H. Rosenbluth, Adrian P Kells
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Patent number: 10413363Abstract: A method for enhancing a surgical procedure includes providing a three-dimensional model of a patient's organ of a patient based on pre-operative image data of the patient's organ; identifying positional data corresponding to a first position of at least one target treatment anatomy of the patient relative to a second position of an ancillary target anatomy of the patient based on an analysis of the three-dimensional model of the patient's organ of the patient; selecting a puncture location based on the identified positional data; and displaying, by an augmented reality device, a virtual organ object via an augmented reality display system overlaying a real-world environment, the virtual organ object corresponding to the three-dimensional model and visually indicating the selected puncture location.Type: GrantFiled: December 15, 2017Date of Patent: September 17, 2019Assignee: Medtronic, Inc.Inventors: Mina S. Fahim, Peter N. Braido, Ross D. Hinrichsen
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Patent number: 10406384Abstract: The invention provides for medical instrument (200, 400) comprising a magnetic resonance imaging system (202) and a high intensity focused ultrasound system (222). A processor (246) controls the medical instrument. Instructions cause the processor to control (100) the magnetic resonance imaging system to acquire the magnetic resonance data using a pulse sequence (254). The pulse sequence comprises an acoustic radiation force imaging pulse sequence (500, 600). The acoustic radiation force imaging pulse sequence comprises an excitation pulse (512) and a multi-dimensional gradient pulse (514) applied during the radio frequency excitation pulse for selectively exciting a region of interest (239) encompassing a target zone and at least a portion of the beam axis.Type: GrantFiled: June 28, 2013Date of Patent: September 10, 2019Assignee: Profound Medical Inc.Inventor: Max Oskar Köhler
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Patent number: 10398513Abstract: Presented herein are methods, systems, devices, and computer-readable media for image management in image-guided medical procedures. Some embodiments herein allow a physician to use multiple instruments for a surgery and simultaneously provide image-guidance data for those instruments. Various embodiments disclosed herein provide information to physicians about procedures they are performing, the devices (such as ablation needles, ultrasound transducers or probes, scalpels, cauterizers, etc.) they are using during the procedure, the relative emplacements or poses of these devices, prediction information for those devices, and other information. Some embodiments provide useful information about 3D data sets and allow the operator to control the presentation of regions of interest. Additionally, some embodiments provide for quick calibration of surgical instruments or attachments for surgical instruments.Type: GrantFiled: June 7, 2016Date of Patent: September 3, 2019Assignee: InnerOptic Technology, Inc.Inventors: Sharif Razzaque, Andrei State, Caroline Green, Brian Heaney
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Patent number: 10402969Abstract: Systems and methods are provided for a visualization of a multi-modal medical image for diagnostic medical imaging. The systems and methods receive first and second image data sets of an anatomical structure of interest, register the first and second image data sets to a geometrical model of the anatomical structure of interest to form a registered image. The geometrical model includes a location of an anatomical marker. The systems and methods further display the registered image.Type: GrantFiled: March 10, 2017Date of Patent: September 3, 2019Assignee: General Electric CompanyInventors: Eigil Samset, Olivier Gerard, Stian Langeland
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Patent number: 10391335Abstract: A method of monitoring a state of a Linac beam in an MRI-Linac system for real-time in vivo patient dosimetry is provided that includes disposing a Linac beam proximal to a PIN diode of an imaging RF coil to induce RF noise in an MRI image from an MRI imager, and using the MRI imager to monitor the induced RF noise in the MRI image, where a change in a percentage of RF noise in the MRI image is used to determine a state of the Linac beam in the presence of a magnetic field of the MRI imager, where the state of the Linac beam includes an ON state, an Off state, or a relative intensity of the Linac beam.Type: GrantFiled: February 26, 2018Date of Patent: August 27, 2019Assignee: Ingham Institute for Applied Medical ResearchInventors: Gary Liney, Bin Dong
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Patent number: 10386439Abstract: A lung segmentation processor (40) is configured to classify magnetic resonance (MR) images based on noise characteristics. The MR segmenatation processor generates a lung region of interest (ROI) and detailed structure segmentation of the lung from the ROI. The MR segmentation processor performs an iterative normalization and region definition approach that captures the entire lung and the soft tissues within the lung accurately. Accuracy of the segmentation relies on artifact classification coming inherently from MR images. The MR segmentation processor (40) correlates segmented lung internal tissue pixels with the lung density to determine the attenuation coefficients based on the correlation. Lung densities are computed using MR data obtained from imaging sequences that minimize echo and acquisition times. The densities differentiate healthy tissues and lesions, which an attenuation map processor (36) uses to create localized attenuation maps for the lung.Type: GrantFiled: December 10, 2014Date of Patent: August 20, 2019Assignee: KONINKLIKE PHILIPS N.V.Inventors: Yannick Berker, Shekhar Dwivedi, Volkmar Schulz, Lingxiong Shao
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Patent number: 10383542Abstract: A medical system for locating a catheter distal tip within a body using a plurality electrical position sensors and a magnetic position sensor in conjunction with an acceleration sensor or rotational encoder. The system locates the catheter by using signals from the acceleration sensor or rotational encoder and magnetic sensors to compensate for positioning errors associated with electric positioning sensors.Type: GrantFiled: March 12, 2014Date of Patent: August 20, 2019Assignee: ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC.Inventor: Fermin A. Lupotti
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Patent number: 10376258Abstract: A surgical introducer system having a sidewall that forms an introducer passage, and a probe receptacle located at the distal end of the introducer. The probe receptacle has an inner surface having a first lateral size at a proximal receptacle end and a second lateral size in the lateral direction at the distal receptacle end, and the first lateral size is greater than the second lateral size. The inner surface receives the distal tip of a navigation probe and restricts movement of the distal probe tip in the lateral direction, and the sidewall is spaced from the navigation probe shaft to allow the shaft to move in the lateral direction within the passage when the distal probe tip is positioned in the probe receptacle.Type: GrantFiled: December 8, 2016Date of Patent: August 13, 2019Assignee: Vycor Medical, Inc.Inventors: David Cantor, Robert Schaefer
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Patent number: 10368809Abstract: Provided is a method and apparatus for tracking a tumor position, which changes by the movement of a body. According to various aspects, a location of a tumor position of a target organ may be estimated using images of one or more surrounding organs.Type: GrantFiled: June 28, 2013Date of Patent: August 6, 2019Assignee: Samsung Electronics Co., Ltd.Inventors: Jung-bae Kim, Young-kyoo Hwang, Do-kyoon Kim, Won-chul Bang
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Patent number: 10363437Abstract: A method of determining a treatment parameter, includes determining an accumulated dose at a target region that undergoes motion, determining an accumulated dose at a critical region, and determining the treatment parameter based on the determined accumulated dose at the target region and the determined accumulated dose at the critical region, wherein the act of determining the treatment parameter is performed during a treatment session. A method of determining a treatment parameter, includes tracking a position of a target, delivering radiation to the target based on the tracked position, and compensating for an inaccuracy of the tracked position by using information regarding a delivered dose to determine a treatment parameter for a next beam delivery.Type: GrantFiled: December 11, 2008Date of Patent: July 30, 2019Assignee: Varian Medical Systems International AGInventors: Janne Nord, Sami Siljamaki
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Patent number: 10335042Abstract: The present system is directed in various embodiments to methods, devices and systems for sensing, measuring and evaluating compliance in a bodily conduit. In other embodiments, the methods, devices and systems sense, measure, determine, display and/or interpret compliance in a bodily conduit and/or a lesion within the bodily conduit. In all embodiments, the sensing, measuring, determining, displaying and/or interpreting may occur before, during and/or after a procedure performed within the bodily conduit. An exemplary conduit comprises a blood vessel and an exemplary procedure comprises a vascular procedure such as atherectomy, angioplasty, stent placement and/or biovascular scaffolding.Type: GrantFiled: July 16, 2015Date of Patent: July 2, 2019Assignee: Cardiovascular Systems, Inc.Inventors: Victor L. Schoenle, Thomas B. Hoegh, Bruce J. Persson, Kayla Eichers, Matthew Tilstra, Richard C. Mattison, Joseph P. Higgins, Michael J. Grace, Matthew Saterbak, Matthew D. Cambronne, Robert E. Kohler
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Patent number: 10335103Abstract: An image display system, radiation imaging system, image display control program and image display control method, which make the position of an object of interest easier to perceive, are provided. A tomographic image generation section generates a tomographic image DG. A nipple height specification section specifies the height of a nipple P as measured from an imaging plane on the basis of the generated tomographic image DG. An image display control section controls displays at a display, via an interface section, such that an information image IG is displayed together with the generated tomographic image DG. The information image IG indicates the height of the nipple P and the slice height of the tomographic image DG that is being displayed.Type: GrantFiled: March 20, 2015Date of Patent: July 2, 2019Assignee: FUJIFILM CORPORATIONInventor: Masataka Sugahara
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Patent number: 10326975Abstract: Embodiments disclose a real-time surgery method and apparatus for displaying a stereoscopic augmented view of a patient from a static or dynamic viewpoint of the surgeon, which employs real-time three-dimensional surface reconstruction for preoperative and intraoperative image registration. Stereoscopic cameras provide real-time images of the scene including the patient. A stereoscopic video display is used by the surgeon, who sees a graphical representation of the preoperative or intraoperative images blended with the video images in a stereoscopic manner through a see through display.Type: GrantFiled: January 17, 2019Date of Patent: June 18, 2019Assignee: OnPoint Medical, Inc.Inventor: Carlos Quiles Casas
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Patent number: 10324148Abstract: A medical apparatus (300, 400, 500) includes a magnetic resonance imaging system (306); magnetic compensation coils (334, 335) for compensating for magnetic inhomogeneities within the imaging zone; a gantry (308) operable for rotating about the imaging zone; a position sensor (312) for measuring the angular position and the angular velocity of the gantry; at least one magnetic field distorting component (310, 510, 512) in the gantry; and a memory (362) storing machine executable instructions (380, 382, 410, 530, 532) and field correction data (372).Type: GrantFiled: January 16, 2014Date of Patent: June 18, 2019Assignee: KONINKLIJKE PHILIPS N.V.Inventors: Johannes Adrianus Overweg, Falk Uhlemann
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Patent number: 10314523Abstract: A method, system and apparatus for image capture and registration are described. The method includes: obtaining a position of an imaging device in a tracking system frame of reference; obtaining a position of a patient in the tracking system frame of reference; determining, based on the position of the imaging device and the position of the patient, a transformation for registering an imaging device frame of reference with a patient frame of reference; receiving an instruction to capture an image, the instruction including coordinates identifying a target area in the patient frame of reference; applying the transformation to convert the coordinates to the imaging device frame of reference; and controlling the imaging device to capture an image based on the converted coordinates.Type: GrantFiled: November 14, 2014Date of Patent: June 11, 2019Assignee: SYNAPTIVE MEDICAL (BARBADOS) INC.Inventors: Jeff Alan Stainsby, Gal Sela
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Patent number: 10314500Abstract: The present invention discloses a reflectance type PPG-based physiological sensing system with a close proximity triangulation approach toward robustly measuring several physiological parameters including, but is not limited to, heart rate, breathing rate, blood oxygen saturation and pulse wave velocity.Type: GrantFiled: February 10, 2015Date of Patent: June 11, 2019Assignee: LifeQ Global LimitedInventor: Laurence Richard Olivier
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Patent number: 10311586Abstract: Systems and methods for co-registering medical images obtained with different imaging modalities are provided. For instance, images obtained with x-ray imaging, such as x-ray computed tomography (“CT”), can be co-registered with images obtained with magnetic resonance imaging (“MRI”). The different imaging modalities generate images that have different visualization characteristics for tissues; thus, in general, co-registration is accomplished by identifying different anatomical features in the different images and then utilizing a known spatial relationship between those anatomical features to co-register the different images.Type: GrantFiled: September 18, 2014Date of Patent: June 4, 2019Assignee: Synaptive Medical (Barbados) Inc.Inventors: Cameron A. Piron, Jeff Stainsby
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Patent number: 10311601Abstract: Embodiments can provide a computer-implemented method for 3D motion correction for diffusion weighted imaging images, the method comprising acquiring a series of image slices from a medical imaging device; binning the series of image slices into bins, each bin comprising a plurality of slice locations; identifying, for each of the B-values, a dominating breathing state wherein at least one of the plurality of slice locations of the dominating breathing state contains an image slice from the series of images; identifying, for each of the B-values, one or more non-dominating breathing states; and registering, for each of the B-values, all of the one or more non-dominating breathing states to the dominating breathing state.Type: GrantFiled: June 2, 2017Date of Patent: June 4, 2019Assignee: Siemens Healthcare GmbHInventors: Li Zhang, Marcel Dominik Nickel, Tongbai Meng
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Patent number: 10292615Abstract: A method of internal MRI employing at least one active internal MRI detector located within a sample of interest. The method includes applying an MRI pulse sequence to the sample of interest. The MRI pulse sequence includes spatial encoding projections. The method further includes receiving MRI signals at the active internal MRI detector and reconstructing at least one MRI image from the MRI signals using an error minimizing algorithm. The MRI pulse sequence provides an increase in an acquisition speed when reconstructing the at least one MRI image by sparsely under-sampling an image k-space in at least one dimension.Type: GrantFiled: September 20, 2013Date of Patent: May 21, 2019Assignee: THE JOHNS HOPKINS UNIVERSITYInventors: Paul Bottomley, Yi Zhang, Shashank S. Hegde
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Patent number: 10293186Abstract: The invention relates to radiation therapy system. The system includes a five-degree-of-freedom O-shaped arm radiation therapy device and a six-degree-of-freedom parallel radiation therapy bed. The five-degree-of-freedom O-shaped arm radiation therapy device includes an O-shaped arm movement mechanism, a linear accelerator device, a radiation dose detection device and a double-X-ray machine image positioning mechanism. The O-shaped arm movement mechanism includes an O-shaped arm, an accelerator displacement device, a rotational displacement device, a turning displacement device, a horizontal transverse displacement device, and a horizontal longitudinal displacement device. The double-X-ray machine image positioning mechanism includes an X-ray transmitter and receiver. The six-degree-of-freedom parallel radiation includes a base assembly, a connecting rod assembly and a bed plate assembly.Type: GrantFiled: December 8, 2014Date of Patent: May 21, 2019Assignee: SOOCHOW UNIVERSITYInventors: Lining Sun, Fengfeng Zhang
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Patent number: 10290098Abstract: An interventional therapy system may include at least one controller which may obtain a reference image dataset of an object of interest (OOI); segment the reference image dataset to determine peripheral outlines of the OOI in the plurality image slices; acquire a current image of the OOI using an ultrasound probe; select a peripheral outline of a selected image slice of the plurality of slices of the reference image dataset which is determined to correspond to the current image; and/or modify the selected peripheral outline of the image slice of the plurality of slices of the reference image dataset in accordance with at least one deformation vector.Type: GrantFiled: September 30, 2015Date of Patent: May 14, 2019Assignees: Koninklijke Philips N.V., Sunnybrook Research InstituteInventors: Shyam Bharat, Ehsan Dehghan Marvast, Jochen Kruecker, Ananth Ravi, Falk Uhlemann, Cynthia Ming-Fu Kung, Thomas Erik Amthor
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Patent number: 10285700Abstract: A surgical instrument includes a body assembly, a shaft assembly, and an end effector. The end effector has first and second jaws that are configured to receive a tissue therebetween. The end effector also includes a staple cartridge including a plurality of staples and a hydraulic expandable member that is configured to receive a fluid and thereby expand from a contracted state to an expanded state. The hydraulic expandable member is further configured to direct at least one of the plurality of staples toward an anvil of the first jaw for forcing the at least one of the staples against the anvil and forming the at least one of the staples within the tissue.Type: GrantFiled: April 20, 2016Date of Patent: May 14, 2019Assignee: Ethicon LLCInventor: Charles J. Scheib
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Patent number: 10279195Abstract: The invention relates to a method for identifying the location at least one treatment channel from a group of a plurality of treatment channels as wells as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body. According to the invention the identifying method being characterized by the steps of A selecting at least one of said plurality of treatment channels; B reconstructing the actual location of said selected treatment channel relative to said animal body; and C comparing said reconstructed location said pre-planned plurality of locations. Furthermore the system according to the invention is characterized in that identifying means are present for identifying the location of at least one treatment channel from said group of said plurality of inserted treatment channels and comparing said identified location with one or more of said pre-planned locations present in said treatment plan.Type: GrantFiled: June 1, 2016Date of Patent: May 7, 2019Assignee: NUCLETRON B.V.Inventor: Johann Kindlein
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Patent number: 10281537Abstract: MRI apparatus includes an RF coil device, a first radio communication unit, a second radio communication unit, an image reconstruction unit and a judging unit. The RF coil device detects an MR signal, and includes a data saving unit for storing the MR signal. The first radio communication unit wirelessly transmits the MR signal detected by the RF coil device, and the second radio communication unit receives the MR signal from the first radio communication unit. The image reconstruction unit reconstructs image data using the MR signal. The judging unit judges existence of a transmission error in radio communication between the first and second radio communication units. If the transmission error is present, the first radio communication unit wirelessly transmit the MR signal stored in the data saving unit to the second radio communication unit.Type: GrantFiled: February 23, 2018Date of Patent: May 7, 2019Assignee: TOSHIBA MEDICAL SYSTEMS CORPORATIONInventors: Sadanori Tomiha, Hiroki Motohashi
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Patent number: 10279194Abstract: The invention relates to a HDR brachytherapy system comprising an ultrasound sensor for being arranged at the location of a brachytherapy catheter (12), wherein the ultrasound sensor is adapted to generate an ultrasound signal based on ultrasound radiation, which has been sent by an ultrasound imaging device preferentially comprising a TRUS probe (40) and which has been received by the ultrasound sensor. The position of the ultrasound sensor is determined based on the generated ultrasound signal, and based on this position of the ultrasound sensor the pose and shape of the brachytherapy catheter and/or the position of a HDR radiation source are determined. This allows for a very accurate determination of the pose and shape of the brachytherapy catheter and/or of the position of the HDR radiation source, which in turn can lead to an improved HDR brachytherapy.Type: GrantFiled: September 15, 2014Date of Patent: May 7, 2019Assignee: Koninklijke Philips N.V.Inventors: Shyam Bharat, Ehsan Dehghan Marvast, Amir Mohammad Tahmasebi Maraghoosh, Francois Guy Gerard Marie Vignon, Ameet Kumar Jain, Dirk Binnekamp
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Patent number: 10282843Abstract: A method for image analysis comprises receiving one or more current images of a lesion from a body of a person, wherein the one or more current images are electronically captured by and transmitted from a capture device, and analyzing the one or more current images, wherein the analyzing comprises performing image processing to compare the one or more current images captured at a first time to one or more previous images of the lesion captured at a second time prior to the first time, and determining at least one difference between the one or more current images and the one or more previous images based on the comparing. The method further comprises determining a probability that the lesion will become diseased based on the analysis, and recommending a time for a future image capture of the lesion and/or a consultation with a practitioner based on the determined probability.Type: GrantFiled: October 27, 2016Date of Patent: May 7, 2019Assignee: International Business Machines CorporationInventors: Mani Abedini, Adrian Bowling, Rajib Chakravorty, Sergey Demyanov, Rahil Garnavi
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Patent number: 10254284Abstract: The present invention relates to the generation of an Atomic Therapeutic Indicator (ATI) for a test sample by the quantification of manganese; in voxels of a 3D region of the sample, wherein the 3D region is topographically defined by co-ordinates X?×Y?×Z. The ATI is used to assess the radio-responsiveness i.e. sensitivity or resistance to radiation treatment, of a cancer i.e. a tumor/neoplasm. In a preferred embodiment, the present invention relates to a method of generating the ATI, assessing the radio-responsiveness of a tumor/neoplasm based on the ATI and, based on the assessment, either treating or not treating the tumor with radiation.Type: GrantFiled: July 11, 2016Date of Patent: April 9, 2019Assignee: Atomic Oncology Pty LtdInventor: George L. Gabor Miklos
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Patent number: 10241161Abstract: Provided is a technique capable of achieving safety and image quality at the same time in an MRI device using a transmission coil including plural channels. An SAR distribution is calculated, and an imaging parameter is determined for optimizing a radio frequency magnetic field distribution in an imaging region while suppressing a maximum value of an SAR to be equal to or smaller than a predetermined threshold value. The determined imaging parameter includes a radio frequency magnetic field parameter for specifying radio frequency pulses to be transmitted through each of the plural channels. The SAR distribution is calculated using a database that retains an electric field distribution of each of the plural channels for each subject model retained in advance.Type: GrantFiled: July 23, 2014Date of Patent: March 26, 2019Assignee: Hitachi, Ltd.Inventors: Yukio Kaneko, Yoshihisa Soutome, Hisaaki Ochi
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Patent number: 10232193Abstract: According to an embodiment, a particle beam treatment system has: a CT device that is a three-dimensional image acquisition part installed in a treatment room for acquisition of a three-dimensional internal image on a day of treatment; a dose distribution display part that displays a dose distribution in the three-dimensional image acquired on the day of treatment and a dose distribution in treatment plan data designed in advance; a treatment management device that is a selection part to select whether or not to change the treatment plan data based on the dose distribution in the three-dimensional image acquired on the day of treatment and the dose distribution in treatment plan data designed in advance; and an irradiation part that irradiates an affected part with a particle beam according to the treatment plan data based on selection made by the treatment management device.Type: GrantFiled: October 27, 2017Date of Patent: March 19, 2019Assignee: Kabushiki Kaisha ToshibaInventor: Yasushi Iseki
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Patent number: 10188552Abstract: A surgical system provides hands-free control of at least one surgical tool includes a robot having a tool connector, a smart tool attached to the tool connector of the robot, and a feedback control system configured to communicate with the smart tool to provide feedback control of the robot. The smart tool includes a tool that has a tool shaft having a distal end and a proximal end, a strain sensor arranged at a first position along the tool shaft, at least one of a second strain sensor or a torque-force sensor arranged at a second position along the tool shaft, the second position being more towards the proximal end of the tool shaft than the first position, and a signal processor configured to communicate with the strain sensor and the at least one of the second strain sensor or the torque-force sensor to receive detection signals therefrom.Type: GrantFiled: August 15, 2016Date of Patent: January 29, 2019Assignee: The Johns Hopkins UniversityInventors: Xingchi He, Iulian Iordachita, Yuki Horise, Russell H. Taylor, Peter L. Gehlbach
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Patent number: 10188367Abstract: Ultrasound image processing method and ultrasound diagnostic device using the method, the method including: acquiring frame signals generated at different time points; generating, by using the frame signals, a first motion map composed of pixel areas each having a motion, the motion indicating an inter-frame signal change and calculated from corresponding pixel areas of the frame signals; holding a second motion map and creating a third motion map by performing a calculation using motions in the first and second motion maps; and adding emphasis to a frame signal by using the third motion map and generating an ultrasound image from the frame signal. In the method, after the calculation using motions, the third motion map is held in place of the second motion map.Type: GrantFiled: December 10, 2014Date of Patent: January 29, 2019Assignee: KONICA MINOLTA, INC.Inventor: Kazuya Takagi
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Patent number: 10188344Abstract: A system capable of designing an optimum administration form of a magnetic drug is provided. The system determines first information about an side-effect-related organ on which a magnetic drug produces a side effect, based on equipment analysis information after administering the magnetic drug; further determines second information about a drug-efficacy-related organ in which drug efficacy of the magnetic drug should be demonstrated; evaluates the administration form of the magnetic drug based on the first information and the second information; corrects the administration form of the magnetic drug based on an evaluation result; and outputs information of the corrected administration form.Type: GrantFiled: December 25, 2013Date of Patent: January 29, 2019Assignees: IHI CorporationInventors: Yoshihiro Ishikawa, Haruki Eguchi