Combined With Therapeutic Or Diverse Diagnostic Device Patents (Class 600/411)
  • Patent number: 10548506
    Abstract: Systems and methods for manufacturing and using magnetic resonance (“MR”) visible labels, markers, or assemblies to encode information unique to the subject or object being imaged by a magnetic resonance imaging (“MRI”) system are provided. The use of such MR-visible labels, markers, or assemblies enables unique information associated with the subject or object being imaged to be encoded into the images of the subject or object. This information can be used to anonymize protected health information (“PHI”); to provide detailed information about a surgical simulation device, quality assurance phantom, or the like; to provide spatial orientation and registration information; or so on.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: February 4, 2020
    Assignee: SYNAPTIVE MEDICAL (BARBADOS) INC.
    Inventors: Gregory A. Whitton, Timotheus Gmeiner, Fergal Kerins
  • Patent number: 10551456
    Abstract: In a method, apparatus and medical imaging system to generate image data based on magnetic resonance (MR) thermometry data, planning data of a region of an examination subject that is to be depicted thermometrically are provided to a processor. Through the processor, segmentation data based on the planning data are generated MR thermometry data are provided to the processor, which generates image data on the basis of the MR thermometry data, using the segmentation data.
    Type: Grant
    Filed: February 13, 2014
    Date of Patent: February 4, 2020
    Assignee: Siemens Aktiengesellschaft
    Inventors: Joerg Roland, Eva Rothgang, Michael Suehling
  • Patent number: 10536686
    Abstract: An exoscope with enhanced depth of field imaging is provided. The exoscope includes first and second sets of optical devices, the first set having a fixed image plane, the second set having a variable image plane adjacent the fixed image plane of the first set. The second set includes at least one variable device configured to change the position of the variable image plane. A beamsplitter splits light from a combined optical path of the first and second set to respective image devices of the first and second set of optical devices. A controller controls the at least one variable device to change the position of the variable image plane relative to the fixed image plane, combines images acquired by the respective image devices, and controls a display device to render a combined image.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: January 14, 2020
    Assignee: SYNAPTIVE MEDICAL (BARBADOS) INC.
    Inventors: William La, Siu Wai Jacky Mak
  • Patent number: 10517490
    Abstract: A method for producing an image representative of the vasculature of a subject using a MRI system includes the acquisition of a signal indicative of a subject' cardiac phase. During each heartbeat of the subject, image slices of a volume covering a region of interest (ROI) within the subject are acquired by applying a volume-selective venous suppression pulse to suppress (a) venous signal for an upper slice in the ROI; (b) venous signal for slices that are upstream for venous flow in the ROI; and (c) background signal from the upstream slices. Next, a slice-selective background suppression pulse is applied to suppress background signal of the upper slice. Following a quiescent time interval, a spectrally selective fat suppression pulse is applied to the entire volume to attenuate signal from background fat signal. Then, a simultaneous multi-slice acquisition of the upper slice and the upstream slices is performed.
    Type: Grant
    Filed: October 24, 2016
    Date of Patent: December 31, 2019
    Assignees: Siemens Healthcare GmbH, Northshore University Healthsystem
    Inventors: Shivraman Giri, Robert R. Edelman, Ioannis Koktzoglou, Himanshu Bhat
  • Patent number: 10511822
    Abstract: Embodiments disclose a real-time surgery method and apparatus for displaying a stereoscopic augmented view of a patient from a static or dynamic viewpoint of the surgeon, which employs real-time three-dimensional surface reconstruction for preoperative and intraoperative image registration. Stereoscopic cameras provide real-time images of the scene including the patient. A stereoscopic video display is used by the surgeon, who sees a graphical representation of the preoperative or intraoperative images blended with the video images in a stereoscopic manner through a see through display.
    Type: Grant
    Filed: July 22, 2019
    Date of Patent: December 17, 2019
    Assignee: OnPoint Medical, Inc.
    Inventor: Carlos Quiles Casas
  • Patent number: 10506991
    Abstract: A method includes, receiving (i) a set of two-dimensional (2D) slices of a segmented three-dimensional (3D) anatomical image of an organ of a patient, and (ii) position signals that are indicative of respective position and orientation of a distal tip of a medical tool in the organ. An optical axis of the medical tool is estimated based on the position signals. A slice that is: (i) oriented at a predefined angle relative to the optical axis, and (ii) includes the position of the distal tip, is selected from among the slices. The selected slice is displayed to a user, together with a marker indicative of the position of the distal tip.
    Type: Grant
    Filed: August 31, 2017
    Date of Patent: December 17, 2019
    Assignee: Biosense Webster (Israel) Ltd.
    Inventor: Assaf Govari
  • Patent number: 10495706
    Abstract: Combined MRI and radiotherapy installations require complex Faraday cage structure that encloses the room, the MRI magnets, and the patient volume, but excludes the linear accelerator path and its supply cabling. A problem with this is that the MRI magnets tend to vibrate when in use, and if physically connected to a rigid structure then the vibrations will be passed to that structure also. To alleviate this, we propose that the Faraday cage be made of a mix of prefabricated conductive sections and flexible sections of a conductive sheet. The flexible conductive sheet can be copper or aluminium, in the form of a foil or mesh.
    Type: Grant
    Filed: November 7, 2018
    Date of Patent: December 3, 2019
    Assignee: Elekta Limited
    Inventors: Jurgen Michael Mikeska, Andreas Michael Hainke
  • Patent number: 10492709
    Abstract: Body-mountable devices are provided to detect the presence or status of an analyte in subsurface vasculature of a body by detecting fluorescent reporters that are bound to instances of the analyte in the subsurface vasculature. Such devices further operate to exert an attractive magnetic force on magnetic nanoparticle-containing probes that are configured to bind to the analyte, thus concentrating the analyte proximate the devices by magnetically exerting attractive forces on such probes that are bound to instances of the analyte. The analyte can be an extracellular vesicle that is characteristic of a cancer, and a body-mountable device as described herein could be used to detect such extracellular vesicles in a portion of subsurface vasculature such that a presence or status of a tumor could be determined based on an amount, presence, or other detected property of the extracellular vesicle.
    Type: Grant
    Filed: October 14, 2016
    Date of Patent: December 3, 2019
    Assignee: Verily Life Sciences LLC
    Inventors: Mark Audeh, Joshua Simon Klein, Anthony M Giannetti, Stephen Morton, James Michael Higbie
  • Patent number: 10495707
    Abstract: In beta emission imaging, magnetic lensing allows a lower resolution detector to detect the spatial distribution of emissions at a higher resolution. The sample is placed in a magnetic field with field lines at a given density, and the detector is placed away from the sample where the magnet field lines diverge, resulting in a lesser density. Since the beta emissions travel along the field lines, the divergence of the field lines from the sample to the detector result in lensing or magnification. Using positron attenuation tomography to detect annihilation in the detector allows for correction due to self-absorption by the sample. The correction and lensing are used together or may be used independently.
    Type: Grant
    Filed: May 16, 2018
    Date of Patent: December 3, 2019
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventor: Charles C. Watson
  • Patent number: 10485992
    Abstract: It is an object of the invention to provide for a system, method and computer program product enabling monitoring of effects of intrafraction motion during the radio therapy treatment. According to a first aspect of the invention this object is achieved by an ultrasound guided radiotherapy system, comprising a radiotherapy system configured for providing a radiation treatment by means of a radiation beam to a treatment target. The ultrasound guided radiotherapy system further comprises an ultrasound imaging system configured for acquiring a 3D online image of the treatment target and/or an organ at risk during the radiation treatment.
    Type: Grant
    Filed: June 6, 2016
    Date of Patent: November 26, 2019
    Inventors: Harald Sepp Heese, Torbjorn Vik, Heinrich Schulz, Christian Buerger, Jochen Peters
  • Patent number: 10481114
    Abstract: A core holder for a reservoir rock core sample for MR or MRI measurement including a casing and a chamber internal to the core holder, an inlet and an outlet in the core holder for circulating a confining fluid in the chamber, a sample housing in the chamber for containing the core sample, the sample housing including an inlet and an outlet in the sample holder for circulating fluid to and from the sample, and a membrane for isolating the sample from fluid contact with the confining fluid but permitting fluid pressure to be exerted on the sample when the confining fluid is pressurized, the space in the chamber not occupied by the sample housing defining a void space, an RF probe in the void space and at least partially surrounding the sample housing, whereby confining fluid introduced into the chamber circulates in the void space around the RF probe.
    Type: Grant
    Filed: August 11, 2017
    Date of Patent: November 19, 2019
    Assignee: University of New Brunswick
    Inventors: Mojtaba Shakerian, Bruce J. Balcom
  • Patent number: 10475192
    Abstract: During a focused-ultrasound or other non-invasive treatment procedure, the motion of the treatment target or other object(s) of interest can be tracked in real time based on (i) the comparison of treatment images against a reference library of images that have been acquired prior to treatment for the anticipated range of motion and have been processed to identify the location of the target or other object(s) therein and (ii) complementary information associated with the stage of the target motion during treatment.
    Type: Grant
    Filed: June 10, 2016
    Date of Patent: November 12, 2019
    Assignee: INSIGHTEC, LTD.
    Inventor: Yoav Levy
  • Patent number: 10463855
    Abstract: A system and a method for optimizing the configuration of multisite transcranial current stimulation, including providing an electric field characteristic target map on the brain's cortex, the target map including multiple cortical targets, the multiple cortical targets are localized and/or continuously varying and spatially extended, providing a weight map on the cortical surface prioritizing the important of areas in the target map for the purposes of optimization; and calculating, based on the target and weight maps, optimal currents and optimal locations for a plurality of electrodes intended for providing transcranial current stimulation to globally stimulate at once the multiple cortical targets with excitatory, inhibitory or neutral stimulation.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: November 5, 2019
    Assignees: NEUROELECTRICS BARCELONA S.L., BETH ISRAEL DEACONESS MEDICAL CENTER
    Inventors: Giulio Ruffini, Oscar Ripolles Mateu, Alvaro Pascual-Leone, Michael D. Fox, Pedro Michael Cavaleiro Miranda
  • Patent number: 10463880
    Abstract: An applicator device (100, 200, 300) for use in interventional brachytherapy, wherein the applicator device (100, 200, 300) is configured to be inserted in, or near a region of interest within a living body, and the applicator device is defining a lumen (101, 201, 301) for receiving a radiation source (103, 203, 303), characterized in that the applicator device (100, 200, 300) comprises one or more sensor elements (102, 202, 302) each configured to generate an output signal indicative of whether or not the radiation source (103, 203, 303) is at a predetermined position in the lumen (101, 201, 301).
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: November 5, 2019
    Assignee: Koninklijke Philips N.V.
    Inventors: Guillaume Leopold Theodorus Frederik Hautvast, Dirk Binnekamp
  • Patent number: 10456594
    Abstract: A brachytherapy method and apparatus include implanting an applicator having at least one radiation source or seed receiving channel (62) into soft tissue adjacent a target region (40) to be irradiated. A high resolution planning image (64) of the target region including the applicator is generated, wherein the high resolution planning image is used for determining a three-dimensional treatment plan (66). A position of the applicator is tracked relative to the target region (40) and the treatment plan (66). Tracking the position includes measuring, via shape-sensing, a location and shape of the at least one radiation source or seed receiving channel (62).
    Type: Grant
    Filed: November 17, 2010
    Date of Patent: October 29, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Laurent Verard, Luis Felipe Gutierrez, Dirk Binnekamp
  • Patent number: 10448003
    Abstract: An intraoperative, marker-less visualization system and method for visualizing three-dimensional surface structures and depth structures of a patient during an intervention. A C-arm carries a C-arm projection module and a camera, and visualization spectacles include an HMD (head-mounted device) projection module and a camera. The projection modules serve for projecting structured light. A processor computes a combined image data set in order to project the latter onto spectacle lenses of the visualization spectacles.
    Type: Grant
    Filed: March 31, 2015
    Date of Patent: October 15, 2019
    Assignee: Siemens Aktiengesellschaft
    Inventor: Alexander Grafenberg
  • Patent number: 10433929
    Abstract: A method for registering a catheter navigation system to a three-dimensional image generally includes obtaining a three-dimensional image including position information for a plurality of surface points on a part of a patient's body, using a catheter navigation system to place a tool at a location on the surface of the patient's body, measuring position information for the surface location, identifying a corresponding location on the image, associating position information for the surface location and the location identified on the image as a fiducial pair, and using at least one fiducial pair to generate a mapping function. The mapping function transforms points within the coordinate system of the catheter navigation to the coordinate system of the three-dimensional image such that, for each fiducial pair, the mapping error is about zero. Suitable warping algorithms include thin plate splines, mean value coordinates, and radial basis function networks.
    Type: Grant
    Filed: March 9, 2007
    Date of Patent: October 8, 2019
    Assignee: St. Jude Medical, Atrial Fibrillation Division, Inc.
    Inventors: Eric S. Olson, Eric J. Voth, Jeffrey A. Schweitzer
  • Patent number: 10426374
    Abstract: The present disclosure provides methods for targeting a biomedical system. Aspects of the subject methods include determining the trajectory of a targeting device using magnetic resonance imaging (MRI) of a MRI-visible style of a trajectory guide that is compatible with the targeting device. Targeted biomedical systems may be utilized for a variety of purposes including targeted delivery of a therapeutic, holding a therapeutic device, positioning of a therapeutic device and other uses. Also provided are devices and systems that can be used in practicing the described methods including but not limited to trajectory guides and adjustable targeting systems, as well as non-transitory computer readable medium storing instructions that, when executed by a computing device, cause a computing device to perform steps of the described methods.
    Type: Grant
    Filed: July 18, 2018
    Date of Patent: October 1, 2019
    Assignee: The Regents of the University of California
    Inventors: Krystof S. Bankiewicz, Kathryn H. Rosenbluth, Adrian P Kells
  • Patent number: 10413363
    Abstract: A method for enhancing a surgical procedure includes providing a three-dimensional model of a patient's organ of a patient based on pre-operative image data of the patient's organ; identifying positional data corresponding to a first position of at least one target treatment anatomy of the patient relative to a second position of an ancillary target anatomy of the patient based on an analysis of the three-dimensional model of the patient's organ of the patient; selecting a puncture location based on the identified positional data; and displaying, by an augmented reality device, a virtual organ object via an augmented reality display system overlaying a real-world environment, the virtual organ object corresponding to the three-dimensional model and visually indicating the selected puncture location.
    Type: Grant
    Filed: December 15, 2017
    Date of Patent: September 17, 2019
    Assignee: Medtronic, Inc.
    Inventors: Mina S. Fahim, Peter N. Braido, Ross D. Hinrichsen
  • Patent number: 10406384
    Abstract: The invention provides for medical instrument (200, 400) comprising a magnetic resonance imaging system (202) and a high intensity focused ultrasound system (222). A processor (246) controls the medical instrument. Instructions cause the processor to control (100) the magnetic resonance imaging system to acquire the magnetic resonance data using a pulse sequence (254). The pulse sequence comprises an acoustic radiation force imaging pulse sequence (500, 600). The acoustic radiation force imaging pulse sequence comprises an excitation pulse (512) and a multi-dimensional gradient pulse (514) applied during the radio frequency excitation pulse for selectively exciting a region of interest (239) encompassing a target zone and at least a portion of the beam axis.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: September 10, 2019
    Assignee: Profound Medical Inc.
    Inventor: Max Oskar Köhler
  • Patent number: 10398513
    Abstract: Presented herein are methods, systems, devices, and computer-readable media for image management in image-guided medical procedures. Some embodiments herein allow a physician to use multiple instruments for a surgery and simultaneously provide image-guidance data for those instruments. Various embodiments disclosed herein provide information to physicians about procedures they are performing, the devices (such as ablation needles, ultrasound transducers or probes, scalpels, cauterizers, etc.) they are using during the procedure, the relative emplacements or poses of these devices, prediction information for those devices, and other information. Some embodiments provide useful information about 3D data sets and allow the operator to control the presentation of regions of interest. Additionally, some embodiments provide for quick calibration of surgical instruments or attachments for surgical instruments.
    Type: Grant
    Filed: June 7, 2016
    Date of Patent: September 3, 2019
    Assignee: InnerOptic Technology, Inc.
    Inventors: Sharif Razzaque, Andrei State, Caroline Green, Brian Heaney
  • Patent number: 10402969
    Abstract: Systems and methods are provided for a visualization of a multi-modal medical image for diagnostic medical imaging. The systems and methods receive first and second image data sets of an anatomical structure of interest, register the first and second image data sets to a geometrical model of the anatomical structure of interest to form a registered image. The geometrical model includes a location of an anatomical marker. The systems and methods further display the registered image.
    Type: Grant
    Filed: March 10, 2017
    Date of Patent: September 3, 2019
    Assignee: General Electric Company
    Inventors: Eigil Samset, Olivier Gerard, Stian Langeland
  • Patent number: 10391335
    Abstract: A method of monitoring a state of a Linac beam in an MRI-Linac system for real-time in vivo patient dosimetry is provided that includes disposing a Linac beam proximal to a PIN diode of an imaging RF coil to induce RF noise in an MRI image from an MRI imager, and using the MRI imager to monitor the induced RF noise in the MRI image, where a change in a percentage of RF noise in the MRI image is used to determine a state of the Linac beam in the presence of a magnetic field of the MRI imager, where the state of the Linac beam includes an ON state, an Off state, or a relative intensity of the Linac beam.
    Type: Grant
    Filed: February 26, 2018
    Date of Patent: August 27, 2019
    Assignee: Ingham Institute for Applied Medical Research
    Inventors: Gary Liney, Bin Dong
  • Patent number: 10386439
    Abstract: A lung segmentation processor (40) is configured to classify magnetic resonance (MR) images based on noise characteristics. The MR segmenatation processor generates a lung region of interest (ROI) and detailed structure segmentation of the lung from the ROI. The MR segmentation processor performs an iterative normalization and region definition approach that captures the entire lung and the soft tissues within the lung accurately. Accuracy of the segmentation relies on artifact classification coming inherently from MR images. The MR segmentation processor (40) correlates segmented lung internal tissue pixels with the lung density to determine the attenuation coefficients based on the correlation. Lung densities are computed using MR data obtained from imaging sequences that minimize echo and acquisition times. The densities differentiate healthy tissues and lesions, which an attenuation map processor (36) uses to create localized attenuation maps for the lung.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: August 20, 2019
    Assignee: KONINKLIKE PHILIPS N.V.
    Inventors: Yannick Berker, Shekhar Dwivedi, Volkmar Schulz, Lingxiong Shao
  • Patent number: 10383542
    Abstract: A medical system for locating a catheter distal tip within a body using a plurality electrical position sensors and a magnetic position sensor in conjunction with an acceleration sensor or rotational encoder. The system locates the catheter by using signals from the acceleration sensor or rotational encoder and magnetic sensors to compensate for positioning errors associated with electric positioning sensors.
    Type: Grant
    Filed: March 12, 2014
    Date of Patent: August 20, 2019
    Assignee: ST. JUDE MEDICAL, ATRIAL FIBRILLATION DIVISION, INC.
    Inventor: Fermin A. Lupotti
  • Patent number: 10376258
    Abstract: A surgical introducer system having a sidewall that forms an introducer passage, and a probe receptacle located at the distal end of the introducer. The probe receptacle has an inner surface having a first lateral size at a proximal receptacle end and a second lateral size in the lateral direction at the distal receptacle end, and the first lateral size is greater than the second lateral size. The inner surface receives the distal tip of a navigation probe and restricts movement of the distal probe tip in the lateral direction, and the sidewall is spaced from the navigation probe shaft to allow the shaft to move in the lateral direction within the passage when the distal probe tip is positioned in the probe receptacle.
    Type: Grant
    Filed: December 8, 2016
    Date of Patent: August 13, 2019
    Assignee: Vycor Medical, Inc.
    Inventors: David Cantor, Robert Schaefer
  • Patent number: 10368809
    Abstract: Provided is a method and apparatus for tracking a tumor position, which changes by the movement of a body. According to various aspects, a location of a tumor position of a target organ may be estimated using images of one or more surrounding organs.
    Type: Grant
    Filed: June 28, 2013
    Date of Patent: August 6, 2019
    Assignee: Samsung Electronics Co., Ltd.
    Inventors: Jung-bae Kim, Young-kyoo Hwang, Do-kyoon Kim, Won-chul Bang
  • Patent number: 10363437
    Abstract: A method of determining a treatment parameter, includes determining an accumulated dose at a target region that undergoes motion, determining an accumulated dose at a critical region, and determining the treatment parameter based on the determined accumulated dose at the target region and the determined accumulated dose at the critical region, wherein the act of determining the treatment parameter is performed during a treatment session. A method of determining a treatment parameter, includes tracking a position of a target, delivering radiation to the target based on the tracked position, and compensating for an inaccuracy of the tracked position by using information regarding a delivered dose to determine a treatment parameter for a next beam delivery.
    Type: Grant
    Filed: December 11, 2008
    Date of Patent: July 30, 2019
    Assignee: Varian Medical Systems International AG
    Inventors: Janne Nord, Sami Siljamaki
  • Patent number: 10335042
    Abstract: The present system is directed in various embodiments to methods, devices and systems for sensing, measuring and evaluating compliance in a bodily conduit. In other embodiments, the methods, devices and systems sense, measure, determine, display and/or interpret compliance in a bodily conduit and/or a lesion within the bodily conduit. In all embodiments, the sensing, measuring, determining, displaying and/or interpreting may occur before, during and/or after a procedure performed within the bodily conduit. An exemplary conduit comprises a blood vessel and an exemplary procedure comprises a vascular procedure such as atherectomy, angioplasty, stent placement and/or biovascular scaffolding.
    Type: Grant
    Filed: July 16, 2015
    Date of Patent: July 2, 2019
    Assignee: Cardiovascular Systems, Inc.
    Inventors: Victor L. Schoenle, Thomas B. Hoegh, Bruce J. Persson, Kayla Eichers, Matthew Tilstra, Richard C. Mattison, Joseph P. Higgins, Michael J. Grace, Matthew Saterbak, Matthew D. Cambronne, Robert E. Kohler
  • Patent number: 10335103
    Abstract: An image display system, radiation imaging system, image display control program and image display control method, which make the position of an object of interest easier to perceive, are provided. A tomographic image generation section generates a tomographic image DG. A nipple height specification section specifies the height of a nipple P as measured from an imaging plane on the basis of the generated tomographic image DG. An image display control section controls displays at a display, via an interface section, such that an information image IG is displayed together with the generated tomographic image DG. The information image IG indicates the height of the nipple P and the slice height of the tomographic image DG that is being displayed.
    Type: Grant
    Filed: March 20, 2015
    Date of Patent: July 2, 2019
    Assignee: FUJIFILM CORPORATION
    Inventor: Masataka Sugahara
  • Patent number: 10326975
    Abstract: Embodiments disclose a real-time surgery method and apparatus for displaying a stereoscopic augmented view of a patient from a static or dynamic viewpoint of the surgeon, which employs real-time three-dimensional surface reconstruction for preoperative and intraoperative image registration. Stereoscopic cameras provide real-time images of the scene including the patient. A stereoscopic video display is used by the surgeon, who sees a graphical representation of the preoperative or intraoperative images blended with the video images in a stereoscopic manner through a see through display.
    Type: Grant
    Filed: January 17, 2019
    Date of Patent: June 18, 2019
    Assignee: OnPoint Medical, Inc.
    Inventor: Carlos Quiles Casas
  • Patent number: 10324148
    Abstract: A medical apparatus (300, 400, 500) includes a magnetic resonance imaging system (306); magnetic compensation coils (334, 335) for compensating for magnetic inhomogeneities within the imaging zone; a gantry (308) operable for rotating about the imaging zone; a position sensor (312) for measuring the angular position and the angular velocity of the gantry; at least one magnetic field distorting component (310, 510, 512) in the gantry; and a memory (362) storing machine executable instructions (380, 382, 410, 530, 532) and field correction data (372).
    Type: Grant
    Filed: January 16, 2014
    Date of Patent: June 18, 2019
    Assignee: KONINKLIJKE PHILIPS N.V.
    Inventors: Johannes Adrianus Overweg, Falk Uhlemann
  • Patent number: 10314523
    Abstract: A method, system and apparatus for image capture and registration are described. The method includes: obtaining a position of an imaging device in a tracking system frame of reference; obtaining a position of a patient in the tracking system frame of reference; determining, based on the position of the imaging device and the position of the patient, a transformation for registering an imaging device frame of reference with a patient frame of reference; receiving an instruction to capture an image, the instruction including coordinates identifying a target area in the patient frame of reference; applying the transformation to convert the coordinates to the imaging device frame of reference; and controlling the imaging device to capture an image based on the converted coordinates.
    Type: Grant
    Filed: November 14, 2014
    Date of Patent: June 11, 2019
    Assignee: SYNAPTIVE MEDICAL (BARBADOS) INC.
    Inventors: Jeff Alan Stainsby, Gal Sela
  • Patent number: 10314500
    Abstract: The present invention discloses a reflectance type PPG-based physiological sensing system with a close proximity triangulation approach toward robustly measuring several physiological parameters including, but is not limited to, heart rate, breathing rate, blood oxygen saturation and pulse wave velocity.
    Type: Grant
    Filed: February 10, 2015
    Date of Patent: June 11, 2019
    Assignee: LifeQ Global Limited
    Inventor: Laurence Richard Olivier
  • Patent number: 10311586
    Abstract: Systems and methods for co-registering medical images obtained with different imaging modalities are provided. For instance, images obtained with x-ray imaging, such as x-ray computed tomography (“CT”), can be co-registered with images obtained with magnetic resonance imaging (“MRI”). The different imaging modalities generate images that have different visualization characteristics for tissues; thus, in general, co-registration is accomplished by identifying different anatomical features in the different images and then utilizing a known spatial relationship between those anatomical features to co-register the different images.
    Type: Grant
    Filed: September 18, 2014
    Date of Patent: June 4, 2019
    Assignee: Synaptive Medical (Barbados) Inc.
    Inventors: Cameron A. Piron, Jeff Stainsby
  • Patent number: 10311601
    Abstract: Embodiments can provide a computer-implemented method for 3D motion correction for diffusion weighted imaging images, the method comprising acquiring a series of image slices from a medical imaging device; binning the series of image slices into bins, each bin comprising a plurality of slice locations; identifying, for each of the B-values, a dominating breathing state wherein at least one of the plurality of slice locations of the dominating breathing state contains an image slice from the series of images; identifying, for each of the B-values, one or more non-dominating breathing states; and registering, for each of the B-values, all of the one or more non-dominating breathing states to the dominating breathing state.
    Type: Grant
    Filed: June 2, 2017
    Date of Patent: June 4, 2019
    Assignee: Siemens Healthcare GmbH
    Inventors: Li Zhang, Marcel Dominik Nickel, Tongbai Meng
  • Patent number: 10292615
    Abstract: A method of internal MRI employing at least one active internal MRI detector located within a sample of interest. The method includes applying an MRI pulse sequence to the sample of interest. The MRI pulse sequence includes spatial encoding projections. The method further includes receiving MRI signals at the active internal MRI detector and reconstructing at least one MRI image from the MRI signals using an error minimizing algorithm. The MRI pulse sequence provides an increase in an acquisition speed when reconstructing the at least one MRI image by sparsely under-sampling an image k-space in at least one dimension.
    Type: Grant
    Filed: September 20, 2013
    Date of Patent: May 21, 2019
    Assignee: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Paul Bottomley, Yi Zhang, Shashank S. Hegde
  • Patent number: 10293186
    Abstract: The invention relates to radiation therapy system. The system includes a five-degree-of-freedom O-shaped arm radiation therapy device and a six-degree-of-freedom parallel radiation therapy bed. The five-degree-of-freedom O-shaped arm radiation therapy device includes an O-shaped arm movement mechanism, a linear accelerator device, a radiation dose detection device and a double-X-ray machine image positioning mechanism. The O-shaped arm movement mechanism includes an O-shaped arm, an accelerator displacement device, a rotational displacement device, a turning displacement device, a horizontal transverse displacement device, and a horizontal longitudinal displacement device. The double-X-ray machine image positioning mechanism includes an X-ray transmitter and receiver. The six-degree-of-freedom parallel radiation includes a base assembly, a connecting rod assembly and a bed plate assembly.
    Type: Grant
    Filed: December 8, 2014
    Date of Patent: May 21, 2019
    Assignee: SOOCHOW UNIVERSITY
    Inventors: Lining Sun, Fengfeng Zhang
  • Patent number: 10290098
    Abstract: An interventional therapy system may include at least one controller which may obtain a reference image dataset of an object of interest (OOI); segment the reference image dataset to determine peripheral outlines of the OOI in the plurality image slices; acquire a current image of the OOI using an ultrasound probe; select a peripheral outline of a selected image slice of the plurality of slices of the reference image dataset which is determined to correspond to the current image; and/or modify the selected peripheral outline of the image slice of the plurality of slices of the reference image dataset in accordance with at least one deformation vector.
    Type: Grant
    Filed: September 30, 2015
    Date of Patent: May 14, 2019
    Assignees: Koninklijke Philips N.V., Sunnybrook Research Institute
    Inventors: Shyam Bharat, Ehsan Dehghan Marvast, Jochen Kruecker, Ananth Ravi, Falk Uhlemann, Cynthia Ming-Fu Kung, Thomas Erik Amthor
  • Patent number: 10285700
    Abstract: A surgical instrument includes a body assembly, a shaft assembly, and an end effector. The end effector has first and second jaws that are configured to receive a tissue therebetween. The end effector also includes a staple cartridge including a plurality of staples and a hydraulic expandable member that is configured to receive a fluid and thereby expand from a contracted state to an expanded state. The hydraulic expandable member is further configured to direct at least one of the plurality of staples toward an anvil of the first jaw for forcing the at least one of the staples against the anvil and forming the at least one of the staples within the tissue.
    Type: Grant
    Filed: April 20, 2016
    Date of Patent: May 14, 2019
    Assignee: Ethicon LLC
    Inventor: Charles J. Scheib
  • Patent number: 10279195
    Abstract: The invention relates to a method for identifying the location at least one treatment channel from a group of a plurality of treatment channels as wells as a system for effecting radiation treatment on a pre-selected anatomical portion of an animal body. According to the invention the identifying method being characterized by the steps of A selecting at least one of said plurality of treatment channels; B reconstructing the actual location of said selected treatment channel relative to said animal body; and C comparing said reconstructed location said pre-planned plurality of locations. Furthermore the system according to the invention is characterized in that identifying means are present for identifying the location of at least one treatment channel from said group of said plurality of inserted treatment channels and comparing said identified location with one or more of said pre-planned locations present in said treatment plan.
    Type: Grant
    Filed: June 1, 2016
    Date of Patent: May 7, 2019
    Assignee: NUCLETRON B.V.
    Inventor: Johann Kindlein
  • Patent number: 10281537
    Abstract: MRI apparatus includes an RF coil device, a first radio communication unit, a second radio communication unit, an image reconstruction unit and a judging unit. The RF coil device detects an MR signal, and includes a data saving unit for storing the MR signal. The first radio communication unit wirelessly transmits the MR signal detected by the RF coil device, and the second radio communication unit receives the MR signal from the first radio communication unit. The image reconstruction unit reconstructs image data using the MR signal. The judging unit judges existence of a transmission error in radio communication between the first and second radio communication units. If the transmission error is present, the first radio communication unit wirelessly transmit the MR signal stored in the data saving unit to the second radio communication unit.
    Type: Grant
    Filed: February 23, 2018
    Date of Patent: May 7, 2019
    Assignee: TOSHIBA MEDICAL SYSTEMS CORPORATION
    Inventors: Sadanori Tomiha, Hiroki Motohashi
  • Patent number: 10279194
    Abstract: The invention relates to a HDR brachytherapy system comprising an ultrasound sensor for being arranged at the location of a brachytherapy catheter (12), wherein the ultrasound sensor is adapted to generate an ultrasound signal based on ultrasound radiation, which has been sent by an ultrasound imaging device preferentially comprising a TRUS probe (40) and which has been received by the ultrasound sensor. The position of the ultrasound sensor is determined based on the generated ultrasound signal, and based on this position of the ultrasound sensor the pose and shape of the brachytherapy catheter and/or the position of a HDR radiation source are determined. This allows for a very accurate determination of the pose and shape of the brachytherapy catheter and/or of the position of the HDR radiation source, which in turn can lead to an improved HDR brachytherapy.
    Type: Grant
    Filed: September 15, 2014
    Date of Patent: May 7, 2019
    Assignee: Koninklijke Philips N.V.
    Inventors: Shyam Bharat, Ehsan Dehghan Marvast, Amir Mohammad Tahmasebi Maraghoosh, Francois Guy Gerard Marie Vignon, Ameet Kumar Jain, Dirk Binnekamp
  • Patent number: 10282843
    Abstract: A method for image analysis comprises receiving one or more current images of a lesion from a body of a person, wherein the one or more current images are electronically captured by and transmitted from a capture device, and analyzing the one or more current images, wherein the analyzing comprises performing image processing to compare the one or more current images captured at a first time to one or more previous images of the lesion captured at a second time prior to the first time, and determining at least one difference between the one or more current images and the one or more previous images based on the comparing. The method further comprises determining a probability that the lesion will become diseased based on the analysis, and recommending a time for a future image capture of the lesion and/or a consultation with a practitioner based on the determined probability.
    Type: Grant
    Filed: October 27, 2016
    Date of Patent: May 7, 2019
    Assignee: International Business Machines Corporation
    Inventors: Mani Abedini, Adrian Bowling, Rajib Chakravorty, Sergey Demyanov, Rahil Garnavi
  • Patent number: 10254284
    Abstract: The present invention relates to the generation of an Atomic Therapeutic Indicator (ATI) for a test sample by the quantification of manganese; in voxels of a 3D region of the sample, wherein the 3D region is topographically defined by co-ordinates X?×Y?×Z. The ATI is used to assess the radio-responsiveness i.e. sensitivity or resistance to radiation treatment, of a cancer i.e. a tumor/neoplasm. In a preferred embodiment, the present invention relates to a method of generating the ATI, assessing the radio-responsiveness of a tumor/neoplasm based on the ATI and, based on the assessment, either treating or not treating the tumor with radiation.
    Type: Grant
    Filed: July 11, 2016
    Date of Patent: April 9, 2019
    Assignee: Atomic Oncology Pty Ltd
    Inventor: George L. Gabor Miklos
  • Patent number: 10241161
    Abstract: Provided is a technique capable of achieving safety and image quality at the same time in an MRI device using a transmission coil including plural channels. An SAR distribution is calculated, and an imaging parameter is determined for optimizing a radio frequency magnetic field distribution in an imaging region while suppressing a maximum value of an SAR to be equal to or smaller than a predetermined threshold value. The determined imaging parameter includes a radio frequency magnetic field parameter for specifying radio frequency pulses to be transmitted through each of the plural channels. The SAR distribution is calculated using a database that retains an electric field distribution of each of the plural channels for each subject model retained in advance.
    Type: Grant
    Filed: July 23, 2014
    Date of Patent: March 26, 2019
    Assignee: Hitachi, Ltd.
    Inventors: Yukio Kaneko, Yoshihisa Soutome, Hisaaki Ochi
  • Patent number: 10232193
    Abstract: According to an embodiment, a particle beam treatment system has: a CT device that is a three-dimensional image acquisition part installed in a treatment room for acquisition of a three-dimensional internal image on a day of treatment; a dose distribution display part that displays a dose distribution in the three-dimensional image acquired on the day of treatment and a dose distribution in treatment plan data designed in advance; a treatment management device that is a selection part to select whether or not to change the treatment plan data based on the dose distribution in the three-dimensional image acquired on the day of treatment and the dose distribution in treatment plan data designed in advance; and an irradiation part that irradiates an affected part with a particle beam according to the treatment plan data based on selection made by the treatment management device.
    Type: Grant
    Filed: October 27, 2017
    Date of Patent: March 19, 2019
    Assignee: Kabushiki Kaisha Toshiba
    Inventor: Yasushi Iseki
  • Patent number: 10188552
    Abstract: A surgical system provides hands-free control of at least one surgical tool includes a robot having a tool connector, a smart tool attached to the tool connector of the robot, and a feedback control system configured to communicate with the smart tool to provide feedback control of the robot. The smart tool includes a tool that has a tool shaft having a distal end and a proximal end, a strain sensor arranged at a first position along the tool shaft, at least one of a second strain sensor or a torque-force sensor arranged at a second position along the tool shaft, the second position being more towards the proximal end of the tool shaft than the first position, and a signal processor configured to communicate with the strain sensor and the at least one of the second strain sensor or the torque-force sensor to receive detection signals therefrom.
    Type: Grant
    Filed: August 15, 2016
    Date of Patent: January 29, 2019
    Assignee: The Johns Hopkins University
    Inventors: Xingchi He, Iulian Iordachita, Yuki Horise, Russell H. Taylor, Peter L. Gehlbach
  • Patent number: 10188367
    Abstract: Ultrasound image processing method and ultrasound diagnostic device using the method, the method including: acquiring frame signals generated at different time points; generating, by using the frame signals, a first motion map composed of pixel areas each having a motion, the motion indicating an inter-frame signal change and calculated from corresponding pixel areas of the frame signals; holding a second motion map and creating a third motion map by performing a calculation using motions in the first and second motion maps; and adding emphasis to a frame signal by using the third motion map and generating an ultrasound image from the frame signal. In the method, after the calculation using motions, the third motion map is held in place of the second motion map.
    Type: Grant
    Filed: December 10, 2014
    Date of Patent: January 29, 2019
    Assignee: KONICA MINOLTA, INC.
    Inventor: Kazuya Takagi
  • Patent number: 10188344
    Abstract: A system capable of designing an optimum administration form of a magnetic drug is provided. The system determines first information about an side-effect-related organ on which a magnetic drug produces a side effect, based on equipment analysis information after administering the magnetic drug; further determines second information about a drug-efficacy-related organ in which drug efficacy of the magnetic drug should be demonstrated; evaluates the administration form of the magnetic drug based on the first information and the second information; corrects the administration form of the magnetic drug based on an evaluation result; and outputs information of the corrected administration form.
    Type: Grant
    Filed: December 25, 2013
    Date of Patent: January 29, 2019
    Assignees: IHI Corporation
    Inventors: Yoshihiro Ishikawa, Haruki Eguchi