Abstract: The present invention relates to a method for determining the position of at least one object in a navigation system of co-ordinates, wherein: reference points and/or markers (4) are connected in a defined positional relationship to the object; the position of the object is detected in relation to a detection system of co-ordinates; the position of the reference points (4) is detected in relation to the detection system of co-ordinates; the position of the reference points is detected in relation to a navigation system of co-ordinates; and the position of the object is determined in the navigation system of co-ordinates, from the position of the at least one reference point (4) in the detection system of co-ordinates; as well as to a device for determining the position of an object in a navigation system of co-ordinates.

Abstract: A computer-based system generating audible feedback to assist with guidance of at least one trackable point in space is provided. Surgical embodiments include generating audible feedback (to supplement visual and tactile feedback) to a surgeon moving the tip of a probe, for example, in a surgical field with respect to a volume of interest such as a tumor. Other surgical embodiments include generating audible feedback to assist with the precise insertion of a pedicle screw. In such surgical embodiments, as a surgeon moves a probe or instrument within the surgical field, a computer analyzes the current position of the probe and/or instrument in space with respect to a system of fiducial markers.

Abstract: The present invention provides systems and methods for guiding a surgical instrument into a preselected spatial relationship with a lesion, in particular a lesion of the breast. In an exemplary embodiment, the system includes a data translation system that translates a set of data points representing the position of the lesion into a set of three dimensional coordinates, and also includes a tracking system that tracks the position of a surgical instrument in three dimensional space, and further includes a representation system that produces a representation of the position of the surgical instrument relative to the lesion. The systems of the present invention are correlated with methods for biopsying a lesion and for surgically removing a lesion.

Abstract: The present invention relates to systems and methods of performing magnetic resonance imaging (MRI) in awake animals. The invention utilizes head and body restrainers to position an awake animal relative to a radio frequency dual coil system operating in a high field magnetic resonance imaging system to provide images of high resolution without motion artifact.

Abstract: An instrument guide is described for mounting an invasive instrument such as a biopsy needle to an imaging probe, controlling its position, monitoring its position, and/or predictively displaying its position on a user display of the medical imaging system. A plurality of substantially rigid segments are hingeably connected to the probe, to an instrument handle, and to each other such that movement of the biopsy needle is restricted to within the imaged plane. However, substantial freedom of movement within the imaged plane is provided such that the instrument may be inserted into the patient over a wide range of angles. In one preferred embodiment, angle detectors are provided at each segment intersection and measurements provided for computing and displaying the instrument position and orientation on the user display. The instrument guide/position monitor is preferably made with low-cost components such that it is disposable after a single use.

Abstract: In a method for acquiring an image of a plane in a magnetic resonance apparatus, the images are obtained in imaging planes which are defined directly with respect to the patient. The magnetic resonance apparatus includes an imaging volume, a patient support table which positioned in the imaging volume, a position measuring device to establish and maintain in real time the position of the patient, as well as a controller for controlling gradient coils in response to the signals provided by the position measuring device in such a manner that consecutive images are acquired from imaging planes which are defined directly with respect to the patient.

Abstract: A non-implantable CT and MRI marker has a first component formed of at least one of a silicone resin and a fluorcarbon resin and a second component comprised of at least one of an elastomer and an organogel contained in the first component.

Abstract: A stereotactic device for use with an imager such as a magnetic resonance imager is disclosed, which permits an imaging scan to be taken with reference to a personal coordinate system (or PCS) that is independent of a machine coordinate system (or MCS). Methods using the device to obtain imaging scans are described such that the imaging scans are superimposable even if taken at different time periods using the same or a different imager. The device comprises a frame that can be reproducibly positioned on a subject and which is equipped with non-invasive affixing means and localizing means that provide the PCS. The device and methods of the invention are particularly well suited for routine initial or follow-up examinations, pre-surgical planning and post-surgical evaluation. Markers on a stereotactic device can be tracked during an MRI scan to compensate for patient motion during the scan.

Abstract: The invention describes a system, method, and means for an MRI guidewire that can be visible on an MRI, can act as an antenna and receive MRI signals from surrounding subject matter, and can allow the use of multiple interventional tools without removal of the guidewire from a subject.

Abstract: The combination of contrast enhanced magnetic resonance imaging (MRI) and MR-guided subcutaneous core biopsy can be used as a robust approach for the diagnosis and treatment of breast cancer. MRI provides the means to accurately position and monitor interventional procedures such as biopsy, removal of tissue or other transcanular procedures. MRI may also be used in this invention to position and monitor the progress of breast conserving therapies (BCT), such as laser photo-ablation, cryoablation and localized hyperthermia. The general practice of this invention is to provide a remotely controlled apparatus for MR-guided interventional procedures in the breast. The apparatus allows the practice of a method that provides flexibility in conditioning the breast, i.e. orientation and degree of compression, and in setting the trajectory of the intervention.

Abstract: A method and apparatus for treating disease by injecting a treatment substance directly into the diseased body part, and thereby leaving the remaining body parts relatively unaffected. Specific treatment substance formulations are provided for each of a plurality of body parts for specific diseases. The treatment substance formulations contain two principle parts including a preferred active treatment (therapy) substance, and a preferred inactive binding (carrier) substance for thickening the treatment substance such as a specific gel or viscous material for carrying the preferred active treatment (therapy) substance for a particular disease and body part. The method also provides preferred treatment substance dosages to be injected into each body part. Apparatus for injecting the treatment substance is also provided that can be used with endoscopic instruments.

Abstract: A system for positioning and repositioning a portion of a patient's body with respect to a treatment or imaging machine includes multiple cameras to view the body and the machine. Index markers are identified and located by the cameras in 3D space. In one embodiment, such index markers are in a determinable relationship to analogous markers used during previous image scanning of the patient. Anatomical targets determined from image scanning can be located relative to reference positions associated with the treatment of diagnostic machine. Several forms of camera, index markers, methods and systems accommodate different clinical uses. X-ray imaging of the patient further refines anatomical target positioning relative to the treatment of diagnostic imaging reference point. Movements of the patient based on comparative analysis of imaging determined anatomical targets relative to reference points on treatment or diagnostic apparatus are controlled by the system and process of the invention.

Abstract: A reference frame adapted to be fitted to a subject of medical treatment and provided with markers for determining the position or the orientation of the subject comprises fitting section for fitting the reference frame with the subject at least three spots (tops of the left and right ears and the nasal projection) along the undulations of the surface thereof and three or more than three markers detectable at least ether in an X-ray image or in an MRI image of the reference frame, the markers being to be arranged at predetermined positions not connectable by a straight line. A surgical operation navigating system determines the coordinates of the markers in a coordinate system defined for the image taken for the purpose of medical examination of the subject who is carrying the reference frame on the basis of the obtained image.

Abstract: A rapid vascular endothelium function examining method with improved reproducibility is provided. An apparatus for the method comprises systems for acquiring ultrasound images by an ultrasound probe, processing the acquired images and moving/rotating the ultrasound probe. The method comprises: a first step where the acquired image is processed so that the center of a blood vessel is laid on the center of the image; a second step where a series of operations for acquiring an image, processing the acquired image and moving the probe based on the processed result, are repeated so that the probe is moved in parallel to the blood vessel; a third step where the similar operations to the second step are executed so that the probe is moved in parallel to and immediately above the blood vessel; a fourth step for determining a blood vessel diameter from the finally acquired image at the third step.

Abstract: A method and apparatus wherein an application of energy is limited to a specific diseased portion of body tissue (target tissue) for the purpose of localizing the treatment to the target tissue and avoiding an adverse effect on surrounding tissue. In one embodiment, access to the target tissue is provided by inserting an energy transmission device through a needle for delivery of the energy into the target tissue. Guidance of the needle is alternatively enhanced through use of an image guidance device. Alternatively, in addition the localized treatment is further controlled by use of an energy-concentrating/enhancement agent and/or photosensitizing/photoselective agent, chromophore dye and viscous substance to cause selective interaction with a specific wavelength of an energy source. The treatment can be further controlled and localized by improving the accuracy and positioning of the delivery device into the target tissue using imaging guidance.

Abstract: Method and system are presented for guiding a diagnostic or therapeutic instrument towards a correct target inside the patient's body. A combined image obtained by registering structural and functional images of at least a portion of the patient's body including the target is used together with a guiding device. The guiding device has an indicator associated with the instrument, and is operable for presenting data indicative of a position of a location on the instrument relative to any other point in the at least portion of the patient's body. The guiding device is connectable to a computer device displaying the combined image and operable thereby for guiding the instrument towards the target.

Abstract: The invention relates to a method for determining the effect of magnetic stimulation on human brain. According to the method, the stimulation dose is determined in different parts of the brain by summing cumulatively the electric field strength generated by the individual stimulus pulses. According to the invention, the position and alignment of a magnetic stimulation coil (1) is determined separately for each applied stimulus pulse in three dimensions relative to the head (5), the number, repetition rate and intensity generated by the magnetic stimulation coil (1) are measured separately for each pulse, the coordinate data of the brain are determined substantially unambiguously in the same coordinate system with the magnetic stimulation coil (1) on the basis of information obtained from other kind of measurement, such as a tomographic scan or, e.g.

Abstract: The systems and methods of the present invention provide for MRI probes adapted for insertion into a plurality of body orifices, in order to evaluate the anatomy of proximate anatomic structures, to diagnose abnormalities thereof and to treat the diagnosed abnormalities. MRI probes are described that are suitable for use in the mediastinum, in the pancreaticohepaticobiliary system, in the tracheobronchopulmonary system, in the head and neck, in the genitourinary system, the gastrointestinal system, the vascular system, and in the evaluation, diagnosis and treatment of internal fluid collections.

Abstract: A computer controlled system for guiding the needle device, such as a biopsy needle, by reference to a single mode medical imaging system employing any one of computed tomography imaging (CTI) equipment, magnetic resonance imaging equipment (MRI), fluoroscopic imaging equipment, or 3D ultrasound system, or alternatively, by reference to a multi-modal imaging system, which includes any combination of the aforementioned systems. The 3D ultrasound system includes a combination of an ultrasound probe and both passive and active infrared tracking systems so that the combined system enables a real time image display of the entire region of interest without probe movement.

Abstract: The invention relates to: a method for stimulating and/or inhibiting at least one point or area of a brain using at least one stimulation device, wherein: the spatial structure of the head or brain is recorded; a three-dimensional simulation model of the surface of the brain is generated from the recording of the spatial structure of the brain; and the stimulation device is arranged relative to the head or brain using the three-dimensional simulation model of the surface of the brain, such that the at least one point or area of the brain can be stimulated using the stimulation device; a device for stimulating and/or inhibiting at least one point or area of a brain, comprising a recording device for detecting the spatial structure of the brain, a computational device for generating a simulation model of the surface of the brain and at least one stimulation or induction device, in particular a coil; a method for determining the function of a particular area of the brain, wherein at least one particular area is

Abstract: An imaging modality, in particular a mobile CT system, comprises an imaging system for imaging an object to be examined. The imaging modality is also provided with an image guided surgery system which includes a position measuring system for measuring positions within the object and a data processor for deriving a transformation between positions within the object and the corresponding positions in the image. The position measuring device is also arranged to measure the position of the imaging system and the data processor is arranged to derive the transformation from the position and/or orientation of the imaging system. The position measuring system is notably an optical position measuring system which is arranged to measure the position of the gantry of the CT system. The data processor is arranged to derive the transformation from the measured position of the gantry.

Abstract: A computer assisted surgery system for accurate positioning of a drill bit into a body part. The system includes a drill guide and a drill with attached localizing emitters whose poses are determined by a localizing device. The drill bit is attached to the drill and the location of the tip of the drill bit is determined during a calibration step. During drilling, the drill bit is inserted through the bore of the drill guide and the pose of the drill bit is calculated from measured position data of both the drill guide and drill. A graphic representation of the drill bit is then displayed on a monitor screen in an appropriate position relative to stored images or other surgical instruments.

Abstract: The combination of contrast enhanced magnetic resonance imaging (MRI) and MR-guided subcutaneous core biopsy can be used as a robust approach for the diagnosis and treatment of breast cancer. MRI provides the means to accurately position and monitor interventional procedures such as biopsy, removal of tissue or other transcanular procedures. MRI may also be used in this invention to position and monitor the progress of breast conserving therapies (BCT), such as laser photo-ablation, cryoablation and localized hyperthermia. The general practice of this invention is to provide a remotely controlled apparatus for MR-guided interventional procedures in the breast. The apparatus allows the practice of a method that provides flexibility in conditioning the breast, i.e. orientation and degree of compression, and in setting the trajectory of the intervention.

Abstract: An insertable intracavity probe for use in Magnetic Resonance Imaging (MRI) and therapy of a region of interest proximal to a cavity, the probe having a substantially rigid probe shell for insertion into the cavity. The probe shell is adapted to incorporate at least one device for imaging the region of interest. A guide track is incorporated in the probe shell and is adapted to guide at least one biopsy or therapy device to the region of interest during imaging. Intracavity regions include cervical, rectal, and other regions associated with internal cavities of a patient.

Abstract: A navigation apparatus comprises a navigation-related information generating section and a display section. The navigation-related information generating section measures the position and orientation of an object and a target in a three-dimensional space and generate navigation-related information to be used for navigating the object toward the target. The display section displays the navigation-related information generated by the navigation-related information generating section in any of different modes depending on the relationship of the position and orientation of the object and that of the target. A surgical operation image acquisition/display apparatus comprises an observation section, an image display section and a specifying section. The observation section includes a plurality of observation sections whose position and orientation is modifiable.

Abstract: A customized positioning fixture is fabricated specifically for a patient the purpose of positioning a portion, or all, of the patient's body relative to a medical apparatus. The customized positioning fixture is fabricated such that the relative position of the patent to the medical apparatus is predetermined before a procedure is performed on the patient using the apparatus. The positioning fixture is fabricated using a computer-aided or an automated computer-controlled process according to data determined for that patient, for example, using a rapid prototyping and tooling (RPT) technique. In some embodiments, the positioning fixture is designed to be repeatedly removed and reattached to the patient, thereby allowing the patient to be repeatedly precisely re-positioned in the medical device is separated sessions.

Abstract: A medical diagnostic imaging device has a support device, which, for positioning a fixable area of an examination subject to be imaged in an imaging volume of the device, is fashioned for moving the examination subject thereon in at least one moving direction, a control device for controlling the movement of the support device, a pointer device, which, for prescribing the area to be imaged, is fashioned for pointing to the area to be imaged, and an detection device, acquires the spatial position of the pointer device at least in the moving direction and which is connected to the control device for positioning the area to be imaged that is prescribed by the pointer device.

Abstract: An MRI guided surgical apparatus includes a heat source formed by a laser and an optical fiber carrying the heat energy into a part to be coagulated by hyperthermia with an end reflector to direct the energy in a beam to one side of the fiber end. The fiber includes a reinforcing sleeve along its length to prevent bending and twisting. The sleeve is mounted in a shielded, Piezo-electric motor which causes movement of the fiber longitudinally of its axis to move the end within the part and rotation of the fiber about its axis to cause the beam to rotate about the axis. A rigid elongate cannula is arranged for insertion to a position at the part of the patient having a bore for receiving a portion of the fiber adjacent the outlet end in sliding engagement therein such that the end can pass through the cannula into engagement with the part of the patient. A part of the sleeve projecting beyond the cannula is rigid and a further part connecting to the motor is stiff but less rigid.

Abstract: The present invention includes stereotactic vectors, no electronic calculations and imaging, diagnostic and treatment techniques. The invention also includes machines or instruments using those aspects of the invention. The present invention also includes methods and processes using the devices of the present invention.

Abstract: A system for utilizing and registering at least two surgical navigation systems during stereotactic surgery. The system comprises a first surgical navigation system defining a first patient space, a second surgical navigation system defining a second patient space, and a translation device to register the coordinates of the first patient space to the coordinates of the second patient space. The translation device comprises a rigid body, at least one component for a first navigation system placed in or on the rigid body, and at least one component for a second navigation system placed in or on the rigid body, in known relation to the at least one component for the first navigation system. The translation device is positioned in a working volume of each of the at least two navigation systems.

Abstract: In a method for acquiring an image of a plane in a magnetic resonance apparatus the images are obtained in planes to be imaged which are defined directly with respect to the patient. Therefore, the magnetic resonance apparatus comprises an imaging volume and a patient support table which can be positioned in this imaging volume, position measuring means being provided so as to establish and maintain in real time the position of the patient as well as control means for controlling gradient coils in response to the signals provided by the position measuring means in such a manner that the consecutive images are acquired from imaging planes which are defined directly with respect to the patient.

Abstract: A method for use during a procedure on a body. The method generates a display representing relative positions of two structure during the procedure.

Abstract: A system for quantitative computer graphic determination of positions on a patient's anatomy and positions on associated equipment located near the patient's anatomy in relation to anatomical data, as from CT or MR scanning. A first camera produces a quantitative electronic readout of its field-of-view which provides a determination of relative spacial coordinates of uniquely identifiable points in its field-of-view. A second camera produces a quantitative electronic readout of its field-of-view which provides a determination of relative spacial coordinates of uniquely identifiable points in its field-of-view. The two cameras are located with respect to the patient's anatomy and the associated equipment so that the fields-of-view of the cameras include both the patient's anatomy and the equipment, but are taken from different directions. A body marker is positioned with respect to the patient's anatomy at a known position relative to said patient anatomy.

Abstract: The invention relates to a method for referencing a patient or a patient body part in a camera-assisted, medical navigation system comprising the following steps:

Abstract: A surgical alignment device is shown that is controlled remotely through the use of an actuator, where the actuator in turn controls at least one local adjustment device. The alignment device is suited for neurosurgery, although it is not exclusively limited to neurosurgery. The alignment device includes an insertion guide that is coupled to the local adjustment device, the insertion guide being used to guide a device such as a catheter into a patient. The alignment device may also be coupled to a control module such as a microcomputer that controls the orientation of the insertion guide in response to inputs from the surgeon as to a location of interest within the patient.

Abstract: The invention refers to an apparatus for positioning medical treatment devices or treatment supporting devices (2) by a transportation means (1) to move said devices (2) to a predetermined position, said transportation means (1) including an automatically guided transport system (3, 7), and to a corresponding method and the use of an automatically guided transport system to perform said positioning tasks.

Abstract: A surgical instrument support is provided having an articulated arm with first structure on a proximal end of the arm. A lockable target ball is rotatably mounted on a distal end of the articulated arm, and the lockable ball has a diametric hole therein for receiving and supporting a surgical instrument. A mount has second structure that receives and secures the proximal end of the articulated arm. The first structure on the articulated arm cooperates with the second structure on the mount to automatically align the proximal end of the articulated arm with the mount in a repeatable relationship. The mount is adapted to be releasably attached to a fixed structure. Thus, after establishing a desired alignment of the lockable ball to a patient, the articulated arm can be removed from the fixed structure and then subsequently remounted therein without losing the desired alignment of the lockable ball with the patient.

Abstract: A magnetic stereotaxis system (MSS) is functionally integrated with a magnetic resonance imaging (MRI) system to provide a non-invasive, radiation-free modality for integrated MRI/MMS tracking and guiding of an interventional medical device. Shielding is provided between regions where the patient is moved so that magnetic fields from one procedure do not interfere with the function or materials used in the other procedure. A process is described where a patient is moved on a track from one procedural field to another procedural field with the shield available between different zones provides for the procedures. A computer is associated with the system to supervise performance of a variety of functions and procedures within the surgical environment.

Abstract: There is disclosed a method of positioning an interventional device in a body using a guide pivoting about a pivot point, comprising locating the spatial coordinates of a target and the pivot point, determining a third point outside of the body lying along or proximate a line extending through the target and pivot point, and aligning the axis of the guide with the third point using an imaging system. There is also disclosed a medical imaging system including a processing unit and computer software operative on the processing unit to permit an operator of the system to locate the spatial coordinates of a target point and a pivot point of a guide, and determine a third point outside of the body lying along or proximate a line extending through the target and pivot point. This medical imaging system may further include computer software operative on the processing unit to assist an operator in obtaining an image by which the axis of the guide can be aligned with the third point using an imaging system.

Abstract: The present invention relates to a restraining assembly used in neuroimaging of animals in magnetic resonance imaging (MRI) systems. The body of the animal under study is secured within a tube with a head holder to reduce motion artifacts, particularly when the animal is awake. The tube is placed in the bore of the MRI system to conduct imaging procedures with a radio frequency coil adjacent to the animals' head.

Abstract: The present invention comprises a device and method for targeted drug delivery, and especially intracranial inflsion or retroperfusion drug delivery using nonlinear magnetic stereotaxis in combination with magnetic resonance (MR) imaging and/or X-ray visualization. An MR-visible and/or X-ray visible drug delivery device is positioned by non-linear magnetic stereotaxis at a site such as an intracranial target site, its location is verified via MR imaging, and it is then used to deliver a biologically active material such as a diagnostic or therapeutic drug solution into that site (such as the brain) at constant or variable rates. The spatial distribution kinetics of the injected or infised drug agent may be monitored quantitatively and non-invasively using real-time MR-imaging such as water proton directional diffusion MR imaging, to establish the efficacy of targeted drug delivery.

Abstract: A surgical method and apparatus for accurately aligning the trajectory of, guiding of, and introducing or withdrawal of an instrument is disclosed. The apparatus includes a base which has a movable member movably attached to the base. The movable member has a passage therein which forms a portion of the trajectory path. A positioning stem further includes a first locator and a second locator. The first and second locators are associated with two different portions of the positioning stem so that they are essentially two points on a line. The first and second locators are also locatable by a scanning or imaging system. The positioning stem is removably attached to said movable member and used to position the movable member. Moving the movable member also moves the passage therein to different trajectories. Once the passage within the movable member more or less is aligned with a target within the body, a locking member locks the movable member into a fixed position.

Abstract: An apparatus and method are disclosed for displaying a path between a selected target and selected points on a patient's skull and for guiding surgical instruments along any selected path. The system is comprised of an image display system, an articulated arm and probe, and a stereotactic system. The sub-systems are coupled to one another so that the articulated probe may be used to select patient fiducial points that correspond to selected image fiducial points. Using these points, the image display system coregisters the external locations to the displayed images so that the probe condition may be displayed with the displayed images. The system further permits the identification of a selected target within a patient's brain and to project a path from the external position to the target prior to the performance of a craniotomy. After evaluation of the path, a surgeon may lock the stereotactic system in place to preserve a selected surgical path and to guide instruments along that path.

Abstract: This invention involves apparatus and methods for relating image scan data of a patient's anatomy from an imaging scanner to a device attached to said patient's anatomy or to an apparatus located nearby said patient's anatomy. In one embodiment it includes identification of fiducial points or markers on or near the patient's anatomy in the image scan data, and subsequently relating these fiducial points to reference points or structures connected to an apparatus attached to or nearby the patient's body. Such an apparatus might be a surgical head clamp or stereotactic frame or arc which has been attached to the patient's head at the time of surgery. A mapping is made between the coordinate frame data of the scan image to the coordinate reference frame of the patient attachment means or external apparatus by physically referencing the fiducial points to the patient attachment means or external apparatus.

Abstract: A system for utilizing and registering at least two surgical navigation systems during stereotactic surgery. The system comprises a first surgical navigation system defining a first patient space, a second surgical navigation system defining a second patient space, and a translation device to register the coordinates of the first patient space to the coordinates of the second patient space. The translation device comprises a rigid body, at least one component for a first navigation system placed in or on the rigid body, and at least one component for a second navigation system placed in or on the rigid body, in known relation to the at least one component for the first navigation system. The translation device is positioned in a working volume of each of the at least two navigation systems.

Abstract: The present invention provides a method of recording and displaying in context of an image a location of at least one point-of-interest in a body during an intra-body medical procedure.

Abstract: A method of reconstructing a map of a volume, including determining coordinates of a plurality of locations on a surface of the volume having a configuration, generating a grid of points defining a reconstruction surface in 3D space in proximity to the determined locations, for each of the points on the grid, defining a respective vector, dependent on a displacement between one or more of the points on the grid and one or more of the locations, and adjusting the reconstruction surface by moving substantially each of the points on the grid responsive to the respective vector, so that the reconstruction surface is deformed to resemble the configuration of the surface.

Abstract: A surgical method and apparatus for accurately aligning the trajectory of, guiding of, and introducing or withdrawal of an instrument is disclosed. The apparatus includes a base which has a movable member movably attached to the base. The movable member has a passage therein which forms a portion of the trajectory path. A positioning stem further includes a first locator and a second locator. The first and second locators are associated with two different portions of the positioning stem so that they are essentially two points on a line. The first and second locators are also locatable by a scanning or imaging system. The positioning stem is removably attached to said movable member and used to position the movable member. Moving the movable member also moves the passage therein to different trajectories. Once the passage within the movable member more or less is aligned with a target within the body, a locking member locks the movable member into a fixed position.

Abstract: There is disclosed a method of positioning an interventional device in a body using a guide pivoting about a pivot point, performed by locating the spatial coordinates of a target and the pivot point, determining a third point outside of the body lying along or proximate a line extending through the target and pivot point, and aligning the axis of the guide with the third point using an imaging system. There is also disclosed a medical imaging system including a processing unit and computer software operative on the processing unit to permit an operator of the system to locate the spatial coordinates of a target point and a pivot point of a guide, and determine a third point outside of the body lying along or proximate a line extending through the target and pivot point. This medical imaging system may further include computer software operative on the processing unit to assist an operator in obtaining an image by which the axis of the guide can be aligned with the third point using an imaging system.

Abstract: A method and an instrument are presented for reliably, accurately and easily locating intracranial targets and guiding surgical instruments to intracranial targets in human patients. An adjustment apparatus and a portable guider 70 constitute main components of the invention. The method and instrument make use of images of natural reference points or fiducial markers found in CT/MRI images of patient's head. In accordance with the present method, after the adjustment apparatus is mechanically adjusted based on the information gathered from CT/MRI images, the adjustments are transferred by a special procedure to the portable guider. The portable guider is the only component employed during surgery, resulting in minimal general intrusion with the work of the surgeon.