Abstract: An apparatus provides phase contrast X-ray image data of a region of interest of an object. Attenuation X-ray image data of the region of interest of the object is also provided. A first basis data set is generated from the phase contrast X-ray image data. A second basis data set is generated from the phase contrast X-ray image data and the attenuation X-ray image data.

Abstract: An MR imaging method with an imaging workflow is provided. Within the scope of the MR imaging method, at least one breath-holding command is output to a patient. An MR imaging is performed with an MR imaging method that may be used with free breathing. A breathing movement of the patient is detected based on measured data acquired when performing the MR imaging method. A time relationship is determined between the breathing movement of the patient and the breath-holding command. The imaging workflow is modified as a function of the determined time relationship. A breathing monitoring device and a magnetic resonance imaging system are also provided.

Abstract: A combined optical coherent tomography (OCT) pressure sensor system includes an optical cable comprising a single-mode core and a multi-mode core. An OCT optical imaging sensor near a distal end of the optical cable can be inserted into a lumen of a living being. First light exiting a distal end of the single-mode core illuminates an interior of the lumen. The OCT optical imaging sensor acquires image information about the interior of the lumen and transmits an optical signal carrying the image information into the distal end of the single-mode core, toward a proximal end of the single-mode core. An optical pressure sensor attached near the OCT optical imaging sensor receives second light from the distal end of the optical cable, senses ambient pressure within the lumen and transmits an optical signal indicative of the ambient pressure into a distal end of the multi-mode core, toward a proximal end of the multi-mode core.

Abstract: A method of processing plaques in magnetic resonance imaging of vessel wall include: step S101, training a generative adversarial network and a capsule neural network to obtain a trained generator network and a trained capsule neural network; and step S102, cascade-connecting the trained generator network with the capsule neural network into a system to recognize and classify plaques in magnetic resonance imaging of vessel wall. In one aspect, the capsule neural network has more abundant vascular plaques characteristic information represented by vector; in another aspect, when the trained generator network and the capsule neural network are cascaded into the system to recognize and classify the plaques in magnetic resonance imaging of vessel wall, an accuracy of recognition and classification may be greatly improved. A device for processing the method as well as a computer for implementing are also disclosed.

Abstract: Systems and methods for ambulatory detection of medical events such as cardiac arrhythmia are described herein. An embodiment of an arrhythmia detection system may include a detection criterion circuit that determines a patient-specific detection criterion using a baseline cardiac characteristic when the patient is free of cardiac arrhythmias. The detection criterion circuit generates a patient-specific threshold of a signal metric by adjusting a population-based threshold of the signal metric, where the manner and the amount of adjustment is based on information about patient baseline cardiac characteristic. The arrhythmia detection system detects an arrhythmia episode using a physiologic signal sensed from the patient and the patient-specific arrhythmia detection threshold.

Abstract: A method is described for planning intracorporeal positioning of a puncture needle to be introduced percutaneously into a patient on the basis of a puncture plan, said method comprising the following steps: a) arranging a needle guide means in a spatially fixed manner on the patient; b) generating and storing a series of cross-sectional images, each containing spatially resolved image information of the patient and of the needle guide means attached in a spatially fixed manner to the patient in a first coordinate system, using an imaging diagnostic method; c) selecting and visually displaying at least one cross-sectional image or a numerically generated cross-sectional image from the series of stored cross-sectional images; d) superimposing a virtual, positionally variable linear trajectory on the basis of the selected cross-sectional image; e) positioning the virtual linear trajectory on the basis of the puncture plan to obtain a target linear trajectory, in which the virtual linear trajectory traverses the

Abstract: A medical image processing apparatus, having a processor configured to divide brains included in a brain image and a standard brain image into a plurality of regions corresponding to each other, calculate a first correction amount between the pixel value of a first reference pixel included in each of the plurality of region in the brain image and the pixel value of a second reference pixel and a second correction amount for matching first other pixel values other than the first reference pixel included in each of the plurality of regions in the brain image with pixel values of second other pixels, and correct the brain image based on the first correction amount and the second correction amount.

Abstract: An image processing method, which is executed by a processor, comprises acquiring a choroidal vascular image, identifying, in the choroidal vascular image, a plurality of blood vessel center points of a choroidal blood vessel along a flow direction of the choroidal blood vessel, and computing a blood vessel diameter for each of the plurality of identified blood vessel center points.

Abstract: An example method for automating a quality assessment of digital fundus image can include: obtaining a digital fundus image file; analyzing a first quality of the digital fundus image file using a model to estimate an optimal time to capture a fundus image; and analyzing a second quality of the digital fundus image file using the model to estimate a disease state.

Abstract: A method for determining access to a patient for performing a surgical procedure in an internal location in the patient's body is disclosed. The method includes forming a three-dimensional model of a portion of the patient's body based on a set of medical images, calculating at least one path for a surgeon to follow to perform the surgical procedure, and determining one or more access zones that the surgeon may use to enter the body. Methods for assisting in the performance of a surgical procedure and performing the surgical procedure are also described and claimed.

Abstract: The invention relates to an apparatus for determining a relation between a surface motion of a body (BD) and an object motion of an object (OB) within the body (BD). The apparatus comprises a first sensing unit configured to acquire a first position signal indicative of a position of a first element placed at the location on the surface of the body with the surface motion; a second sensing unit configured to acquire a second position signal indicative of a position of a second element attached to an interventional device and placed on or in the object, wherein the first position signal and the second position signal are acquired during a given duration synchronously; and a third unit for calculating the relation between the surface motion and the object motion based on the first position signal and the second position signal. The invention also relates to a corresponding method for determining the motion relation.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: A method of radiation therapy comprises, while a gantry of a radiation therapy system rotates continuously in a first direction through a treatment arc from a first treatment delivery position to a second treatment delivery position, causing an imaging X-ray source mounted on the gantry to direct X-rays through a target volume and receiving a set of X-ray projection images from an X-ray imager mounted on the gantry; determining a current location of the target volume based on the set of X-ray projection images; and while the gantry to continues to rotate to the second treatment delivery position, initiating delivery of a treatment beam of a treatment-delivering X-ray source mounted on the gantry to the target volume, and continuing to cause the gantry to rotate in the first direction from the second treatment delivery position to a third treatment delivery position.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: A device or scope device is disclosed. The device may comprise: a handle body extending along an axis between first end and a second end; an actuator at the first end of the handle body; a catheter at the second end of the handle body; and a processing unit communicable with a plurality of devices to: switch-in the actuator for control of one device of the plurality of devices; configure, with the actuator, a setting of the one device, control, with the actuator, the one device based on the setting, and switch-in the actuator for control of another one of the plurality of devices. Related devices and methods also are disclosed.

Abstract: An image processing apparatus includes an acquisition unit that acquires a plurality of pieces of tomographic data indicating tomographic information on substantially the same part of a subject to be inspected, a threshold calculation unit that calculates a threshold from tomographic data associated with a target pixel for which motion contrast data is to be calculated of the plurality of pieces of tomographic data, and a pixel value calculation unit that calculates the pixel value of the target pixel of a motion contrast image based on the threshold and the motion contrast data calculated from the tomographic data associated with the target pixel.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: Medical software tools platforms utilize a surgical display to provide access to specific medical software tools, such as medically-oriented applications or widgets, that can assist surgeons or surgical team in performing various procedures. In particular, an endoscopic camera may register the momentary rise in the optical signature reflected from a tissue surface and in turn transmit it to a medical image processing system which can also receive patient heart rate data and display relevant anomalies. Changes in various spectral components and the speed at which they change in relation to a source of stimulus (heartbeat, breathing, light source modulation, etc.) may indicate the arrival of blood, contrast agents or oxygen absorption. Combinations of these may indicate various states of differing disease or margins of tumors, and so forth. Also, changes in temperatures, physical dimensions, pressures, photoacoustic pressures and the rate of change may indicate tissue anomalies in comparison to historic values.

Abstract: A surgical system includes a bed extending along a main direction, a robotic arm disposed adjacent to the bed, and a surgical guide attached to the robotic arm. The bed has a table top to support a patient, the robotic arm is controllable to move in relation to the body of the patient; and the surgical guide is capable of holding a surgical instrument and measuring a translation of the surgical instrument as it moves through the surgical guide. The robotic arm is configured to position the surgical guide to a desired position in relation to a target area of the patient.

Abstract: Various robotic surgical systems are disclosed. A robotic surgical system comprises: a first robotic arm comprising a first force sensor, a second robotic arm comprising a second force sensor, and a control unit. The control unit comprises a processor and a memory communicatively coupled to the processor. The memory stores instructions executable by the processor to receive a first input from the first force sensor, to receive a second input from the second force sensor, and to effect cooperative movement of the first robotic arm and the second robotic arm based on the first input from the first force sensor and the second input from the second force sensor in a load control mode.

Abstract: Detecting a vessel region in multiple angiographic image frames and defining a direction that perpendicularly intersects a longitudinal direction of the vessel region to improve co-registration between two imaging modalities. Motion of the vessel region is then detected based on the direction that intersects the longitudinal direction of the vessel region by evaluating positions of the vessel region in the multiple angiographic image frames. The method includes defining an area based on the detected motion and the detected vessel region, detecting a marker of an imaging catheter disposed in the vessel region within the area and performing co-registration based on the detected marker.

Abstract: Medical software tools platform utilizes a surgical display to provide access to specific medical software tools, such as medically-oriented applications or tools, that can assist those in the operating room, such as a surgeon or surgical team, with a surgery. In particular, an optical sensor located within an endoscopic camera may register subtle differences in color characteristics reflected from a tissue surface and in turn transmit the information to a medical image processing system. Moreover, the new tools are intended to help surgeons better determine the boundaries between healthy and diseased regions during surgical procedures. Various tools are intended to be used in procedures where indocyanine green (ICG) fluorescent dye is used. Intraoperative fluorescence imaging is commonly used during minimally invasive procedures to enable surgeons to visualize tissue perfusion and anatomical structures. The term perfusion refers to the passage of blood and tissue fluid through the capillary bed.

Abstract: Medical software tools platforms utilize a surgical display to provide access to specific medical software tools, such as medically-oriented applications or widgets, that can assist surgeons or surgical team in performing various procedures. In particular, an endoscopic camera may register the momentary rise in the optical signature reflected from a tissue surface and in turn transmit it to a medical image processing system which can also receive patient heart rate data and display relevant anomalies. Changes in various spectral components and the speed at which they change in relation to a source of stimulus (heartbeat, breathing, light source modulation, etc.) may indicate the arrival of blood, contrast agents or oxygen absorption. Combinations of these may indicate various states of differing disease or margins of tumors, and so forth. Also, changes in temperatures, physical dimensions, pressures, photoacoustic pressures and the rate of change may indicate tissue anomalies in comparison to historic values.

Abstract: A system includes a storage device storing a set instructions and a processor in communication with the storage device, wherein when executing the set of instructions, the processor is configured to cause the system to obtain raw data. The processor may also be configured to cause the system to determine one or more reconstruction-related algorithms and determine one or more containers for the one or more reconstruction-related algorithms. Each of the one or more containers may correspond to at least one of the one or more reconstruction-related algorithms. The system may also be configured determine a reconstruction flow based on the one or more containers and process the raw data according to the reconstruction flow to generate a target image.

Abstract: Disclosed is a console for operating an actuating mechanism, relating to the technical filed of automatic control, and being for use in resolving the technical problem of shift of a controller under the influence of gravity. The console for operating an actuating mechanism includes a controller and a support base. The controller is constrained in both the longitudinal direction and the vertical direction, so that connection between the controller and the support base is tight and reliable, and no displacement would occur in any of three directions (i.e., the longitudinal direction, the horizontal direction, and the vertical direction). Thus, the phenomenon that position information given by the controller is inaccurate due to shift of the controller under the influence of the gravity after long-term usage can be avoided, thereby removing the factors affecting success of surgery, and ensuring the success rate of the surgery.

Abstract: Disclosed herein is a method for quantifying a pigmented lesion using Optical Coherence Tomography (OCT). The method includes (a) irradiating light and receiving an interference signal produced by reflection of the light from first and second boundary layers of a pigmented lesion; and (b) calculating size information of the pigmented lesion using phase information of the interference signal. According to embodiments of the present invention, there is an advantage of allowing calculation of size information of a pigmented lesion using OCT, by increasing a measurement range in the axial direction to which beams are irradiated.

Abstract: A first determination unit performs first determination as to whether or not to store ultrasound images acquired in time series. In a case where the first determination is positive, a storage control unit stores ultrasound images, which are determined to be stored by the first determination unit, in a storage. A second determination unit performs second determination as to whether or not one or more ultrasound images to be stored are stored in the storage. In a case where the second determination is negative, a notification unit notifies that the one or more ultrasound images to be stored are not stored in the storage.

Abstract: A cryosurgical system including a computer system programmed with software configured to perform the following steps: a) capturing at least one first view of a region of interest in a human body; b) capturing at least one second view of the region of interest; c) outlining the region of interest and at least one area outside the region of interest with the assistance of an operator; d) constructing a 3-dimensional model of the region of interest and the at least one area outside the region of interest utilizing the at least one first view and the at least one second view of the region of interest; and e) utilizing the 3-dimensional model of the region of interest and the at least one area outside the region of interest to determine at least one cryosurgical probe placement location.

Abstract: Techniques are described herein for delivering a particle beam composed of a plurality of beamlets from a continuously rotating gantry towards a target, by determining a plurality of predefined spots on the target and configuring them into a set of smaller spots on the outside of the target and a set of larger spots on the inside of the target, optimizing the delivery of the rotating particle beam such that the inside edge and the outside edge of the arc of the rotating beam are delivered to the spots located at the center of the target, and the central component of the arc of the beam is delivered to the spots located at the outside of the target.

Abstract: A robotic system for operating a endovascular deployment device (40) including a treatment device (43) mounted to a delivery tool (42) connected to a proximal control (41), and further including an optical shape sensor (44) (e.g., an endograft endovascular deployment device incorporating an optical shape sensor). The robotic system employs a robot (50) attachable to proximal control (41) and/or delivery tool (42) for navigating the treatment device (43) within a cardiovascular system (e.g., a robot controlling an axial rotation and/or axial translation of an endograft mounted to a sheath catheter). The robotic system further employs a robot controller (74) for controlling a navigation of treatment device (43) within the cardiovascular system by the robot (50) derived from a spatial registration between a shaping sensing by the optical shape sensor (44) of a portion or entirety of endovascular deployment device (40) to a medical image of the cardiovascular system (e.g.

Abstract: The present disclosure relates to a method and system for reducing radiation dose in image acquisition. The method may include obtaining first image data of a subject related to a first scan of the subject. The first scan may be of a first type of scan. The method may include reconstructing a first image of the subject based on the first image data and generating a dose plan of a second scan based on the first image. The second scan may be of a second type of scan. The method may also include obtaining second image data of the subject related to the second scan of the subject. The second scan may be performed according to the dose plan.

Abstract: Systems, methods and devices are disclosed for use in electronic guidance systems for surgical navigation. A sensor is provided with an optical sensor and an inclinometer (e.g. accelerometer or other inclination measuring sensor) and communicates measurements of patient inclination to an inter-operative computing unit. A registration device is useful to construct a registration coordinate frame. The direction of gravity may be used to construct the registration coordinate frame such as determined from inclination measurements.

Abstract: A registration apparatus registers an elongated introduction element (18), like a catheter or a needle, during an interventional procedure, for instance, a brachytherapy or a biopsy. A guide element (13) includes at least one opening which guides the introduction element when being introduced into a living being (2) through the opening. A temperature profile generation element (14) associated with the opening generates a characteristic temperature profile at the opening for being transferred to the introduction element when being present in the opening. A temperature determination unit (15) determines a temperature along the introduction element, and a registration unit (16) registers the introduction element. The registering includes identifying the transferred characteristic temperature profile on the introduction element based on the determined temperature. This allows the registration unit to register the introduction element during the introduction process in a simple and efficient manner.

Abstract: The invention relates to a system for delivering a radiation treatment to a structure (21) within a body. In the system, a plurality of treatments plans is provided, each treatment plan being associated to one of a plurality of predefined possible position (33a; 33b) of the structure (21), which area regularly distributed on at least one predefined surface (32a; 32b). A control unit is configured to determine the position of the structure during the treatment and to select a treatment plan which is associated with a predefined possible position having a smallest distance to the determined position, for controlling the radiation source in response to the detection of the position. Moreover, the invention relates to a computer program for controlling the system and to a planning unit for generating the treatment plans.

Abstract: An ophthalmic measurement and laser surgery system includes: a laser source; a corneal topography subsystem; an axis determining subsystem; a ranging subsystem comprising an Optical Coherence Tomographer (OCT); and a refractive index determining subsystem. All of the subsystems are under the operative control of a controller. The controller is configure to: operate the corneal topography subsystem to obtain corneal surface information; operate the axis determining subsystem to identify one or more ophthalmic axes of the eye; operate the OCT to sequentially scan the eye in a plurality of OCT scan patterns, the plurality of scan patterns configured to determine an axial length of the eye; operate the refractive index determining subsystem so to determine an index of refraction of one or more ophthalmic tissues, wherein at least one of the corneal surface information, ophthalmic axis information, and axial length is modified based on the determined index of refraction.

Abstract: A system and method of checking registration for a surgical system, the surgical system including fiducials and tracking markers, may include: using the fiducials and the tracking markers to register a three-dimensional (3D) imaging space of the surgical system with a 3D tracking space of the surgical system; using a tracking fixture of an X-ray imaging system to register an X-ray imaging space of the X-ray imaging system to the 3D tracking space; obtaining a two-dimensional (2D) X-ray image corresponding to the 3D tracking space; identifying a point of interest in the 2D X-ray image; determining a vector in the 3D tracking space that passes through the point of interest; and/or evaluating the registration of the 3D imaging space with the 3D tracking space based on a location, an orientation, or the location and the orientation of the vector in the 3D tracking space.

Abstract: An endoscope operation support system includes: an image display unit which, transmits external scenery and allows the user to visually recognize the external scenery, and also displays a virtual image as superimposed on the external scenery and allows the user to visually recognize the virtual image; a control unit which controls the image display unit; an endoscope unit having an image pickup unit at a distal end part inserted in an image pickup target part of an object, the image pickup unit picking up an image inside the image pickup target part; and a position detection unit which detects a position of the distal end part. The control unit causes the image display unit to display a position display image including a pointer image indicating the position of the distal end part detected by the position detection unit, as the virtual image superimposed on the object in the external scenery.

Abstract: Systems, methods and devices are disclosed for use in electronic guidance systems for surgical navigation. A sensor is provided with an optical sensor and an inclinometer (e.g. accelerometer or other inclination measuring sensor) and communicates measurements of patient inclination to an inter-operative computing unit. A registration device is useful to construct a registration coordinate frame. The direction of gravity may be used to construct the registration coordinate frame such as determined from inclination measurements.

Abstract: An electromagnetic (“EM”) tracking configuration system employs an EM quality assurance (“EMQA”) (30) and EM data coordination (“DC”) system (70). For the EMQA system (30), an EM sensor block (40) includes EM sensor(s) (22) positioned and oriented to represent a simulated electromagnetic tracking of interventional tool(s) inserted through electromagnetic sensor block (40) into an anatomical region. As an EM field generator (20) generates an EM field (21) encircling EM sensor(s) (22), an EMQA workstation (50) tests an EM tracking accuracy of an insertion of the interventional tool(s) through the EM sensor block (40) into the anatomical region.

Abstract: Systems and methods are disclosed for integrating imaging data from multiple sources to create a single, accurate model of a patient's anatomy. One method includes receiving a representation of a target object for modeling; determining one or more first anatomical parameters of the target anatomical object from at least one of one or more first images of the target anatomical object; determining one or more second anatomical parameters of the target anatomical object from at least one of one or more second images of the target anatomical object; updating the one or more first anatomical parameters based at least on the one or more second anatomical parameters; and generating a model of the target anatomical object based on the updated first anatomical parameters.

Abstract: A radiation tomograph whereby the acquisition of transmission data and the measurement of annihilation radiation pairs are simultaneously performed by a single detector ring so as to realize both reduction of the manufacturing cost of a PET device and reduction of a burden to a subject. The transmission data, which shows the distribution of annihilation radiation absorption characteristics within a subject, is computed from data relating to annihilation radiation pairs in the vicinity of a surface of the subject. The transmission data can be acquired by detecting a radioactive drug derived from the subject, which makes imaging exclusively for transmission data unnecessary.

Abstract: A method and a corresponding system for assessing a haemodynamic parameter for a vascular region of interest of a patient based on angiographic images are provided. After acquiring multiple angiographic images, a three dimensional (3D) representation of at least a first portion of the respective region of interest is performed, and geometric features are extracted from complete or partial views. Additional geometric features are extracted from partial incomplete views. A complete set of 3D geometric features for an anatomical structure, such as a vessel tree, is then generated by combining the extracted geometric features and estimating any missing geometric features. Using the complete set of 3D geometric features, a feature-based assessment of the haemodynamic parameter, such as a fractional flow reserve, is then performed.

Abstract: Systems and methods for generating a radiation therapy treatment plan by using ultrasound images are disclosed. The method includes obtaining a first set of image data representing a first image of an anatomical region that includes a treatment applicator inserted into the anatomical region. The method further includes receiving tracking information indicating a position of the treatment applicator as represented in the first set of image data, obtaining a second set of image data representing a second image of the anatomical region, and combining at least a portion of the first set of image data with the second set of image data. One of the first set and the second set of image data is used to identify a target tissue portion in the anatomical region. The method further includes generating, based on the combined image data, treatment plan information for treating the target tissue portion in the anatomical region.

Abstract: A method of calibrating time in a Positron Emission Tomography (PET) device includes obtaining original time information and energy information of a first pulse signal collected by a detecting module during a scanning process of the PET device. A detector of the PET device includes a plurality of detecting modules. The original time information of the first pulse signal includes a moment at which an amplitude of the first pulse signal begins to be greater than a threshold. The method includes determining a pulse time calibration amount corresponding to the energy information of the first pulse signal according to stored information indicative of a correspondence between the pulse time calibration amount and the energy information of each detecting module. The method includes generating calibrated time information of the first pulse signal by calibrating the original time information with the pulse time calibration amount; and reconstructing a PET image based on the generated calibrated time information.

Abstract: The present application relates to an ultrasound fusion imaging method and an ultrasound fusion image navigation system. The ultrasound fusion imaging method includes a selection step, a registration step and a fusion step. The selection step is for selecting at least one ultrasound image from at least one previously stored piece of ultrasound video data according to an input instruction. The ultrasound video data includes an ultrasound image obtained by acquiring a target object in at least one plane and position indicating information corresponding to the ultrasound image. The registration step is for registering the selected at least one ultrasound image with a modality image. The registration process uses the location of the position indicating information of the at least one ultrasound image. The fusion step is for fusing the registered ultrasound image with the modality image.

Abstract: An ultrasonic transducer includes a piezoelectric element in round shape, an acoustic lens, and an acoustic matching layer. The piezoelectric element generates an ultrasonic sound wave. The acoustic matching layer decreases a reflection of the ultrasonic sound wave from a subject. The piezoelectric element has a center having a hole through which an optical fiber that guides a light of a light source passes. The ultrasonic transducer transmits and receives the ultrasonic sound wave while emitting the light. The acoustic lens has a material using a resin with a withstand voltage, mainly polymethylpentene. The acoustic matching layer has a thickness set to ?/4 by not applying a polyparaxylylene coating for ensuring the withstand voltage on the acoustic matching layer. The optical fiber has a distal end configured not to pass through the acoustic lens. The piezoelectric element and the acoustic matching layer have shapes in a planar surface.

Abstract: System includes a beam generator to generate beam(s) for patient treatment and a computing device that obtains three-dimensional image(s) of a target structure that repositions with respect to surrounding tissue of the patient. The computing device creates plan(s) including a first three-dimensional probability distribution of patient's position and a second three-dimensional probability distribution of the repositioned structure's internal position. The computing device combines the first distribution with the second distribution to generate a joint distribution and selects a probability level from the joint distribution. The probability level defines an enclosed surface. A distance defined between the surface and a point of origin in at least one direction is equal to a threshold value of a parameter of the repositioned target in the direction.