Abstract: An apparatus and modeling method of the present invention includes the successive steps of generating cartographic data representative of points belonging to a glenoid surface; distinguishing from among the cartographic data a first group of cartographic data corresponding to a first part of the glenoid surface, the first surface part being situated farthest down in the vertical direction in relation to the scapula; calculating from the first group of cartographic data a first ellipsoid portion that coincides substantially with the first surface part; and obtaining a theoretical glenoid surface from the first ellipsoid portion. By virtue of the theoretical glenoid surface obtained by this method, it is possible to assist the surgeon in optimizing the position of implantation of a glenoid component and to produce a glenoid component “made to measure” for the scapula that is to be fitted with a prosthesis.

Abstract: Methods and systems for registering three-dimensional (3D) CT image data with two-dimensional (2D) fluoroscopic image data using a plurality of markers are disclosed. In the methods and systems, a lateral angle and a cranial angle are searched for and a roll angle is computed. 3D translation coordinates are also computed. The calculated roll angle and 3D translation coordinates are computed for a predetermined number of times successively. After performing the calculations, the 3D CT image data is overlaid on the 2D fluoroscopic image data based on the lateral angle, the cranial angle, the roll angle, and the 3D translation coordinates.

Abstract: A multi-dimensional solution directed to employment of a low-resolution motion tracking technique to estimate a homogeneous transformation matrix that is further adapted to accurately characterize movement/motion between successive positions of an object through time. Low-resolution tracking is first used to estimate a homogeneous transformation matrix that describes the motion between successive positions of an object as that object moves over time. The 3-dimensional imaging data is then used to calculate a more accurate homogeneous transformation matrix, providing the accuracy to better characterize motion of the object over time. In the case where the ‘object’ being tracked is a 3-dimensional imaging system (herein, 3DIS), the resulting homogeneous transformation matrix is used to create 3-dimensional digital models of the scene that is in the field-of-view of the 3-dimensional imaging system (3DIS).

Abstract: Systems and methods for tracking a target volume, e.g., tumor, in real-time during radiation treatment are provided. Under one aspect, a system includes an ultrasound probe, an x-ray imager, a processor, and a computer-readable medium that stores a 3D image of the tumor in a first reference frame and instructions for causing the processor to: instruct the x-ray imager and ultrasound probe to substantially simultaneously obtain inherently registered x-ray and set-up ultrasound images of the tumor in a second reference frame; establish a transformation between the first and second reference frames by registering the 3D image and the x-ray image; instruct the ultrasound probe to obtain an intrafraction ultrasound image of the tumor; registering the intrafraction ultrasound image with the set-up ultrasound image; and track target volume motion based on the registered intrafraction ultrasound image.

Abstract: A method and system for determining a target location for a medical device having complex geometry relative to an anatomical feature, and for navigating and positioning the medical device at the target location. The system may include a medical device including a treatment element having a centroid, one or more navigation electrodes, and a longitudinal axis and a navigation system in communication with the one or more navigation electrodes, the navigation system including a processing unit. The processing unit may be programmed to define a plane that approximates a surface of the anatomical feature, define a centroid of the anatomical feature, define a vector that is normal to the plane and extends away from the centroid of the anatomical feature, and determine a target location for the treatment element of the medical device based on the vector to assist the user in placing the device for treatment.

Abstract: Disclosed herein are radiation therapy systems and methods. These radiation therapy systems and methods are used for emission-guided radiation therapy, where gamma rays from markers or tracers that are localized to patient tumor regions are detected and used to direct radiation to the tumor. The radiation therapy systems described herein comprise a gantry comprising a rotatable ring coupled to a stationary frame via a rotating mechanism such that the rotatable ring rotates up to about 70 RPM, a radiation source (e.g., MV X-ray source) mounted on the rotatable ring, and one or more PET detectors mounted on the rotatable ring.

Abstract: A dose planning system includes a biopsy map creation module configured for receiving biopsy information for an organ of interest regarding biopsy locations and tissue characteristics of tissue found at the biopsy locations and creating a spatially annotated biopsy map for the organ, by linking the spatial information on the biopsy locations to the tissue characteristics of tissue found at the corresponding biopsy locations. A probability map calculation module is configured for creating a tumor probability map by calculating a tumor probability for locations in the organ from which no biopsy was taken by using the tumor and/or tissue characteristics from the biopsy locations and a dose planning module configured for creating a dose plan based on the tumor probability map. The planning constraints are such that on average a higher tumor probability results in a higher planned dose and a lower tumor probability results in a lower planned dose.

Abstract: Provided is a method for measuring a depth profile of a particle beam, the method including providing first sensors in a first direction in auditory organs of a human body, providing second sensors in a second direction that intersects with the first direction on a top of a head and in a mouth of the human body, providing a particle beam into the head of the human body, detecting an acoustic signal generated by the particle beam through the first and second sensors, and calculating a depth profile of the first and second directions of the particle beam corresponding to a Bragg peak position of the particle beam in the head using the acoustic signal.

Abstract: The radiographic imaging apparatus is configured so that an irradiation device is mounted on a rotary drum of a rotary gantry. A pair of X-ray sources is disposed outside the rotary drum and attached to the outer surface of the rotary drum. A pair of FPDs facing the respective X-ray sources is mounted in the irradiation device. When X-rays are irradiated, X-ray intensity information is calculated by a signal processing device based an output signal from each radiation detection element of each FPD, and stored in a memory. Based on FOV information set by an input device, an X-ray intensity acquisition device acquires multiple pieces of X-ray intensity information that are calculated based on the output signals from the radiation detection elements in small FOV areas (or large FOV areas) of the FPDs, which are included in the X-ray intensity information stored in the memory.

Abstract: Breast monitoring systems and methods are described including a flexible substrate fabricated to substantially conform to one or more breasts of a subject; dynamically bendable optical fibers associated with the flexible substrate; a light source operably coupled to the optical fibers; a photodetector positioned to detect light reception from the optical fibers; a reporting device; and a microcontroller including a microprocessor and circuitry, wherein the circuitry includes input circuitry configured to receive a first set of signals and at least one second set of signals from the photodetector; calculation circuitry configured to calculate a curvature delta value based on a comparison of the received first and at least one second set of signals, and calculate a breast volume delta value from the calculated curvature delta value; and reporting circuitry configured to transmit a signal to the reporting device based on the calculated breast volume delta value.

Abstract: A device for protecting tissue when treating an eye using a laser beam generated by a laser system and deflected by a scanner system comprises an eye model, a control data module and a processor. The eye model comprises eye data which define dimensions and locations of eye structures. The control data module is configured to register control data which define beam parameters of the laser beam and a scanning pattern for the laser beam. The processor is configured to simulate by computation a light spot moving on or in an eye structure on the basis of the eye data and the control data, to add up, for a plurality of measurement points of the eye structure and continuously, a beam dose emitted at the relevant measurement point by the moving light spot and to generate an emergency signal if a dose limit Dmax is exceeded at one of the measurement points.

Abstract: The invention provides a linear sensor including a row 100 of N regularly spaced pixels that are formed in a semiconductor substrate, and a circuit for reading out the N pixels, which delivers an output signal for each of the N pixels of the row, characterized in that the N pixels comprise image-capturing pixels that have a useful photosensitive area in the shape of a rectangle R that is higher than it is wide, where the width is in the direction of the row and the height is in the perpendicular direction, and at least two spaced-apart pairs of alignment-detecting pixels PPL, PPR, wherein the detecting pixels of each pair are pixels P1, P2 that are adjacent in the row 100 of pixels and the useful photosensitive area DT1, DT2 of the detecting pixels has a width that varies monotonically in the height direction, but in opposite directions for the two detecting pixels of a given pair.

Abstract: Radiographic imaging systems and/or methods embodiments capable of both tomosynthesis x-ray imaging and general projection radiography x-ray imaging can include a single x-ray source assembly including a plurality of distributed x-ray sources, where at least one of the plurality of distributed x-ray sources is configured to output a beam sufficient for standard projection radiography, and each of at least two of the plurality of distributed x-ray sources is configured to output a beam at a lower radiation dose sufficient for tomosynthesis. In one embodiment, radiographic imaging systems and/or methods embodiments can include a single x-ray source; a first collimator that is configured to be adjustable for at least two dimensions; and a second collimator that is configured to provide fixed collimation. In one embodiment, a single x-ray source can include a single radiation shield or a single vacuum chamber.

Abstract: Living cells, such as red blood cells (RBCs) modified with functional micromotors with the aid of ultrasound propulsion and magnetic guidance. Iron oxide nanoparticles are loaded into the RBCs, where their asymmetric distribution within the cells results in a net magnetization, thus enabling magnetic alignment and guidance under acoustic propulsion. The RBC motors display efficient guided and prolonged propulsion in various biological fluids, including undiluted whole blood.

Abstract: The invention relates to an imaging apparatus (24) for imaging an introduction element (17) like a needle or a catheter for performing a brachytherapy or a biopsy. A tracking unit (3, 4) tracks the location of the introduction element within a living being (2), an imaging unit (6) like an ultrasound imaging unit generates an image showing an inner part of the living being, which includes the tracked location of the introduction element, based on the tracked location, and a display (7) displays the image. During the brachytherapy or biopsy the display can always show the introduction element, without requiring a manual control. For instance, it is not necessary that a physician manually controls the position and image plane of the imaging unit. This allows for an accurate and fast insertion of the introduction element into the living being such that a target region is reliably reached.

Abstract: The treatment of various sensitive organs with low energy acoustic shockwaves has been proposed. However, the prior art is lacking in guidance as to what constitutes an efficacious minimum dosage or a safe maximum dosage for various target organs and tissues. Through extensive experimentation with cultured cells, live animals, and animal disease models, the inventors of the present disclosure have determined safe and efficacious shockwave energetic dosage ranges for vital and sensitive organs, including the brain, pancreas, kidneys, liver, and spleen, as well as for skin and subcutaneous tissues, peripheral nerves, and skeletal muscles.

Abstract: In various embodiments, the present application discloses systems and methods for magnetic resonance imaging (MRI) of coronary arteries. In various embodiments, the invention allows for motion corrected, simultaneously acquired multiple contrast weighted images with whole-heart coverage and isotropic high resolution. In some embodiments, the invention teaches using interleaved preparatory pulses, a 3D radial golden angle trajectory and 100% respiratory gating efficiency.

Abstract: A lateral retractor system for forming a surgical pathway to a patient's intervertebral disc space includes a single dilator and a retractable dual-tapered-blade assembly. The single dilator may feature a narrow rectangular body for insertion at an insertion orientation parallel to the fibers of the patient's psoas muscle and at an approximate 45-degree angle to the patient's spine. The retractable dual-tapered-blade assembly consists of only two blade subassemblies, each having a blade bordered by adjustable wings, along with built-in video capabilities and lighting control for illuminating the surgical pathway. The dual-tapered-blade assembly may be passed over the single dilator at the insertion orientation and rotated approximately 45-50 degrees from the insertion orientation to a final rotated orientation parallel to the intervertebral disc space before the two blade subassemblies are retracted away from one another to create the surgical pathway. Other embodiments are also disclosed.

Abstract: A system comprises a teleoperational assembly including an operator control system and a plurality of manipulators configured for teleoperation by the operator control system. A first manipulator of the plurality of manipulators is configured to control movement of a first medical instrument in a surgical environment. The system further comprises a processing unit configured to display an image of a field of view of the surgical environment; determine first association information for the first medical instrument, the first association information including information about at least one of the first manipulator or the operator control system; display a first badge proximate to an image of the first medical instrument in the image of the field of view, the first badge including the first association information; and adjust a size of the first badge as the first medical instrument changes depth relative to an imaging instrument capturing the field of view.

Abstract: Embodiments of the present invention provide a system and method to automatically screen images from a plurality of fundus cameras for a plurality of retinal diseases. The system comprises stacked autoencoders, amplitude modulation-frequency modulation filters, and artificial neural networks. An embodiment of the present invention uses a multi-class classifier, such as a support vector machine (multi-class SVM) classifier, to determine a plurality of retinal pathologies. An exemplary embodiment of the present invention is validated on a proprietary database of thousands of images (for example over 250,000 retinal images) from multiple cameras, ranging from the table-top fundus cameras to portable hand-held cameras.

Abstract: A biological information detection device according to an aspect of the present disclosure includes: a light source that, in operation, emits irradiation light for irradiating a test portion of a subject; a light detector that, in operation, detects light reached from the test portion and that outputs an electrical signal corresponding to the light; and a calculation circuit that, in operation, generates a signal of biological information related to a blood flow in a target area in the test portion based on the electrical signal. The light detector is an image sensor. The electrical signal includes an image signal obtained by the image sensor. The calculation circuit, in operation, detects a magnitude of an inclination of an orientation of the test portion with respect to a reference orientation by image recognition based on the image signal, and determines the target area according to the magnitude of the inclination of the orientation of the test portion.

Abstract: One aspect of the present disclosure relates to a system that can employ multi-modal imaging to provide an image with an enhanced resolution. In some instances, the multi-modal imaging can allow an operator to determine and control a tissue margin without the need for intra-operative tissue pathology. The system can include an imaging system that includes a gamma camera to detect a gamma image and an optical imaging modality to detect an optical image. The system can also include a display device to display an enhanced gamma image created based on a function of the optical image. The enhanced gamma image illustrates a characteristic of a disease in the field of view (e.g., a lymphatic pathway, a sentinel lymph node target, or a satellite disease state).

Abstract: An implant planning system aids delivery of radiation to tumor sites of a patient. The system allows a user to test various combinations of virtual implants, each associated with a corresponding physical implant (e.g., a carrier with an embedded radioactive seed), and to view the dosage area of the virtual implants so that adjustments to the virtual implants may be made until a prescribed dose of radiation to a treatment area is achieved. A treatment plan developed based on the virtual implants may then be used in surgical implantation of the corresponding physical implants. For example, the implant configuration of the treatment plan may be projected onto a treatment surface of a patient, such as in a surgical room, so that physical implants may be placed according to the projected image of the virtual implants.

Abstract: The present invention relates to a method for treating the kidney with extracorporeal shockwaves in a noninvasive manner and in particular, to such a method for the treatment of the nephrons about the glomerulus.

Abstract: To generate images, in which a first row area of a multiple-row detector is illuminated with a first X-ray spectrum and a second row area of the multiple-row detector, trailing in the direction of travel, is illuminated with a second X-ray spectrum, image data is recorded at a pitch chosen such that one slice image can be reconstructed in each case for a sectional position for the first and the second row area. Correspondingly, for the sectional position, the respective slice image for the first and the second row area is reconstructed. For a third row area, illuminated with the first and the second X-ray spectrum, a reference sectional image is reconstructed as a slice image. To generate motion-reduced first and second spectral images assigned to the first and second row area respectively, the slice images of the first and second row areas are registered to the reference sectional image.

Abstract: A system for imaging and quantifying shear wave and shear modulus under orthogonal acoustic radiation force (ARF) excitation using the OCT Doppler variance apparatus. The ARF perpendicular or with at least a perpendicular component to the OCT beam is produced by a remote ultrasonic transducer. The OCT Doppler variance apparatus, which is sensitive to the transverse vibration, is used to measure the ARF induced vibration. For analysis of the shear modulus, the Doppler variance apparatus is utilized to visualize shear wave propagation. The propagation velocity of the shear wave is measured and then used to quantitatively map the shear modulus.

Abstract: The present invention relates to medical imaging, and in particular a medical imaging detector. In order to improve and facilitate the collection of information, e.g. for medical diagnosis, a medical imaging detector is provided that comprises a first sensor arrangement (12) and a second sensor arrangement (14). The first sensor arrangement is configured to provide a first type of image data belonging to a first imaging modality. The second sensor arrangement is configured to provide a second type of image data belonging to a second imaging modality. The first imaging modality is an X-ray imaging modality, while the second imaging modality is a non-X-ray imaging modality. The first sensor arrangement comprises one or a plurality of first sensor segments (16) arranged within a first circumferential line (18) defining a first imaging area (20).

Abstract: Medical software tools platforms utilize a surgical display to provide access to specific medical software tools, such as medically-oriented applications or widgets, that can assist surgeons or surgical team in performing various procedures. In particular, an endoscopic camera may register the momentary rise in the optical signature reflected from a tissue surface and in turn transmit it to a medical image processing system which can also receive patient heart rate data and display relevant anomalies. Changes in various spectral components and the speed at which they change in relation to a source of stimulus (heartbeat, breathing, light source modulation, etc.) may indicate the arrival of blood, contrast agents or oxygen absorption. Combinations of these may indicate various states of differing disease or margins of tumors, and so forth. Also, changes in temperatures, physical dimensions, pressures, photoacoustic pressures and the rate of change may indicate tissue anomalies in comparison to historic values.

Abstract: Medical software tools platform utilizes a surgical display to provide access to specific medical software tools, such as medically-oriented applications or tools, that can assist those in the operating room, such as a surgeon or surgical team, with a surgery. In particular, an optical sensor located within an endoscopic camera may register subtle differences in color characteristics reflected from a tissue surface and in turn transmit the information to a medical image processing system. Moreover, the new tools are intended to help surgeons better determine the boundaries between healthy and diseased regions during surgical procedures. Various tools are intended to be used in procedures where indocyanine green (ICG) fluorescent dye is used. Intraoperative fluorescence imaging is commonly used during minimally invasive procedures to enable surgeons to visualize tissue perfusion and anatomical structures. The term perfusion refers to the passage of blood and tissue fluid through the capillary bed.

Abstract: The present application describes computer apparatus and software programs useful to the field of corrective spinal surgery. The apparatus and software implement and facilitate methods for assessing the degree of balance and alignment achieved through corrective measures applied to the spine prior to completing a surgical procedure. The apparatus and software facilitate pre-operative planning and virtual testing of the corrective measures to be applied. The apparatus and software further facilitate intra-operative reconciliation with the pre-operative plan prior to completing the surgery.

Abstract: Medical software tools platforms utilize a surgical display to provide access to specific medical software tools, such as medically-oriented applications or widgets, that can assist surgeons or surgical team in performing various procedures. In particular, an endoscopic camera may register the momentary rise in the optical signature reflected from a tissue surface and in turn transmit it to a medical image processing system which can also receive patient heart rate data and display relevant anomalies. Changes in various spectral components and the speed at which they change in relation to a source of stimulus (heartbeat, breathing, light source modulation, etc.) may indicate the arrival of blood, contrast agents or oxygen absorption. Combinations of these may indicate various states of differing disease or margins of tumors, and so forth. Also, changes in temperatures, physical dimensions, pressures, photoacoustic pressures and the rate of change may indicate tissue anomalies in comparison to historic values.

Abstract: The present application describes computer apparatus and software programs useful to the field of corrective spinal surgery. The apparatus and software implement and facilitate methods for assessing the degree of balance and alignment achieved through corrective measures applied to the spine prior to completing a surgical procedure. The apparatus and software facilitate pre-operative planning and virtual testing of the corrective measures to be applied. The apparatus and software further facilitate intra-operative reconciliation with the pre-operative plan prior to completing the surgery.

Abstract: The present invention relates to a computer-implemented medical method of determining a spatial position of a medical optical observation device (1), the method comprising executing, on a processor of a computer (2), the steps of:—acquiring position data describing, for a plurality of points in time, the spatial position of the observation device (1) within a co-ordinate system of a medical tracking system (3);—determining, based on the position data, average position data describing an average value for the position of the observation device (1) within the co-ordinate system of the medical tracking system (2);—acquiring image data describing a plurality of images acquired at the plurality of points in time via a camera (4) assigned to the observation device (1) and detecting the field of view (5) of the observation device (1);—determining, based on the image data, optical flow data describing an optical flow for the plurality of images;—determining, based on the average position data and the optical flow dat

Abstract: Medical illumination systems and devices for illuminating a target surgical area with a pre-selected type of multispectral light to aid tissue differentiation as viewed by the human eye, especially in open-surgery settings, and methods for practicing the same. A light source may have multiple settings selectable to provide various types of multispectral light configured to reduce reflection from corresponding tissue types relative to full-spectrum light. A pre-selected type of multispectral light may be configured to reduce reflection from blood. An illumination system or device can have one more illumination elements, including combinations of LEDs, lasers, and filtered broadband light sources. The multispectral light may be or comprise one or more of a continuous or pulsed wave.

Abstract: An ophthalmic analysis device for analyzing OCT motion contrast data including blood vessel information of a subject eye acquired by an ophthalmic OCT, includes: a processor; and memory storing computer readable program, when executed by the processor, causing the ophthalmic analysis device to execute: an analysis process of analyzing the OCT motion contrast data to acquire a measurement result related to a capillary area of the subject eye. The analysis process executes an alleviating process for alleviating the influence of great blood vessels having blood vessel diameters larger than those of capillaries on the measurement result to acquire the measurement result related to the capillary area.

Abstract: Medical software tools platform utilizes a surgical display to provide access to specific medical software tools, such as medically-oriented applications or widgets, that can assist those in the operating room, such as a surgeon or surgical team, with a surgery. In particular, an optical sensor located within an endoscopic camera may register the momentary change in the optical characteristics reflected from a tissue surface and in turn transmit the information to a medical image processing system which can also receive patient heart rate data and display relevant anomalies. Changes in various spectral components and the speed at which they change in relation to a source of stimulus (heartbeat, etc.) may indicate the arrival of blood, contrast agents or oxygen absorption. Combinations of these may indicate various states of differing disease or margins of tumors, and so forth. Also, changes in temperatures and the speed of change may indicate subsurface anomalies.

Abstract: [Object] To provide a catheter having a simple structure capable of excising an atheroma in a blood vessel and capable of obtaining ultrasonic images of a blood vessel. [Solution] A catheter 10 has a shaft 11 having an opening 20 in a part of the side wall on the distal end side, a cutter 12 which is located in the vicinity of the opening 20 in the internal space of the shaft 11 and which can move in the axial direction 101 of the shaft 11, a balloon 23 which is disposed on the side opposite to the opening 20 with respect to the axis of the shaft 11 and which outwardly expands from the side wall of the shaft 11, and a phased array ultrasound probe 17 disposed along the circumferential direction 102 of the outer peripheral surface of the side wall in the vicinity of the opening 20 at least on the same side as the side where the opening 20 is provided with respect to the axis of the shaft 11.

Abstract: The present disclosure provides an operation-path recommendation method and apparatus. In the present disclosure, by an operation-path recommendation apparatus, a blood vessel graph model is generated based on patient's anatomical information, a plurality of candidate paths between defined start and destination points is extracted; node information on at least one node in each of the candidate paths is extracted; a cost function is applied to each candidate path, based on the extracted node information.

Abstract: A computer-implemented method for temporal up-to-date representation of a moving section of a body is provided. A first x-ray image data record is provided containing the moving section in a specific movement phase and a first 2D x-ray image and a 3D x-ray image superimposed and registered with one another. 2D x-ray images are repeatedly recorded each containing the moving section. 3D ultrasound images are repeatedly recorded each containing the moving section. Extended 2D x-ray images are created from the 2D x-ray images using the first x-ray images data record. The 3D ultrasound images are used as intermediaries for movement correction. The extended 2D images are displayed.

Abstract: The invention provides a machine for tunnelling in rock. The machine includes a pilot drill assembly for drilling a series of interfering parallel holes or a pilot hole into and generally perpendicular into a rock face and a blast hole drill assembly for drilling a series of blasting holes around the pilot hole or previous blast hole. The machine further includes a charge handling and loading assembly for loading the first series of holes with propellant charges and an ignitor system for igniting the charges. Included further is a rock clearing means for removing the blast rock from the blast face and a rock pick for clearing and picking the floor, roof or walls to provide access for the machine into the tunnel and a mobility assembly for moving the machine forward.

Abstract: An image processing apparatus of the present invention includes an image obtaining unit obtaining first and second three-dimensional images, a deformation information obtaining unit obtaining deformation between two images, a cross-sectional image generating unit generating first and second cross-sectional images, a target position obtaining unit obtaining a target position in the first cross-sectional image, a corresponding position obtaining unit obtaining a corresponding position in the second three-dimensional image which corresponds to the target position on the basis of the deformation information.

Abstract: A technique allows for an electrical connection between a thermal abrasion heating catheter and the energy delivery console that utilizes serial communication. Accordingly, the serial communication allows data such as measured temperature, start/stop status, intended treatment area, device identification, device calibration parameters and/or use history to be conveyed along the same wires that deliver power to a heating element. For example, data can be conveyed along a two wire connection and provided at a frequency that is filtered out so that it is not delivered to a heating feature. In this example, one wire provides power to the heating element, one wire provided communication from the energy delivery console, and a third wire provides a common ground which the heating catheter uses to communicate with the energy delivery console.

Abstract: Methods and systems for improving quantification of OCT angiography data are disclosed. The disclosure specifically relates to methods for compensating for the effect of tissue reflectance to improve the accuracy and repeatability of OCT angiography measurements. These improvements are effected by deriving and then utilizing a dynamic thresholding approach to process decorrelation data to properly classify flow versus non-flow data in OCT angiograms. The disclosed methods overcome quantification errors associated with within-scan variations in reflectance as well as repeatability problems associated with differences in scan quality over successive imaging sessions.

Abstract: An apparatus is provided that is at least partially visible by both a three dimensional (3D) scanner system of a medical navigation system and a tracking system of the medical navigation system. The apparatus includes a rigid member, a plurality of identifiable features attached to the rigid member and visible by the tracking system, a distinct identifiable portion visible by the 3D scanner system, and a connector mechanism attached to the rigid member to connect the apparatus to a location. The apparatus is in a field of view of the 3D scanner system and the tracking system within a timeframe of the 3D scan.

Abstract: Systems and methods for analyzing pathologies utilizing quantitative imaging are presented herein. Advantageously, the systems and methods of the present disclosure utilize a hierarchical analytics framework that identifies and quantify biological properties/analytes from imaging data and then identifies and characterizes one or more pathologies based on the quantified biological properties/analytes. This hierarchical approach of using imaging to examine underlying biology as an intermediary to assessing pathology provides many analytic and processing advantages over systems and methods that are configured to directly determine and characterize pathology from underlying imaging data.

Abstract: A surgical navigation system is disclosed including a camera that is fixedly attached to a patient. The camera space merges with the patient space and thereby eliminates the need for a separate patient tracker. The surgical navigation system calculates the position of a surgical tool with a tracking device in view of the camera and shows on a display device the position of the surgical tool with respect to the patient superimposed and in correlation with a scan image of the patient.

Abstract: A heavy-particle treatment system exposes a patient's treatment volume, during the course of a single treatment session, to beams of heavy particles from a variety of different angles. The source of heavy particles may rotate about the patient to facilitate that variety of different angles. The foregoing can occur pursuant to a treatment plan that accounts for a penetration range as corresponds to the beams of heavy particles and for using at least one lateral beam controlling device to control at least one of the beams of heavy particles.

Abstract: A method for reconstructing a Computer Tomography (CT) image is disclosed. The method may comprise: obtaining a X-ray projection data frame and a dynamic sensor information data frame, wherein the X-ray projection data frame may include a first timestamp indicating acquisition time of X-ray projection data and the dynamic sensor information data frame may include a second timestamp indicating acquisition time of dynamic sensor information data; extracting the first timestamp from the X-ray projection data frame and extracting the second timestamp from the dynamic sensor information data frame; searching X-ray projection data and dynamic sensor information data which may be acquired in same sampling period according to a first timestamp and a second timestamp; and reconstructing a CT image according to the searched X-ray projection data and dynamic sensor information data which may be acquired in the same sampling period.

Abstract: The invention comprises an apparatus and method of use thereof for extracting ions from an ion source, such as for use in cancer treatment or tomographic imaging. The extraction apparatus uses a triode extraction system, with the ion source and/or first electrode held at a first potential; an extraction electrode held at a second potential; and a gating electrode, positioned between the ion source and the extraction electrode, oscillating and/or alternating between a first suppression potential proximate that of the ion source potential and a second extraction potential between the ion source potential and the extraction electrode potential. Optionally, the ion source comprises an electron cyclotron resonance ion source.

Abstract: A calibration system includes a channel block (102) having a plurality of channels (104) formed therein. The channels are configured to correspond to locations where treatment devices are inserted for treatment of a patient. The channels are dimensioned to restrict motion of the treatment devices. A tracking system (128) is configured to monitor a position of a treatment device (108) inserted in one or more of the channels. The tracking system is configured to generate tracking data for the at least one treatment device for comparison with an expected position for the treatment device.