Abstract: Blood pressure is estimated in a non-constraining manner continuously and in real time. A biological signal collected from a person's dorsal part is analyzed, vibration in the human body ascribable to a blood flow rate change in a period from the ventricular filling period to the isovolumetric systole is captured, and the state of fluctuation of an index indicating the state of the in vivo vibration is further captured. This fluctuation index correlates with a person's blood pressure. Therefore, it is possible to estimate whether the blood pressure is in a range indicating a normal-range blood pressure or in a range indicating a high blood pressure, only by having the person sit or lie supine on a surface provided with a biological signal measurement device to measure a biological signal in a non-constraining manner, so as to make the biological signal measurement device contiguous with the person's dorsal part.

Abstract: In some examples, a device includes a memory configured to store a first relationship between a blood pressure and another physiological parameter of a patient, the first relationship being indicative of cerebral autoregulation of the patient. The device also includes processing circuitry configured to receive first and second signals indicative of the blood pressure and the physiological parameter, respectively, of a patient. The processing circuitry is also configured to determine an expected value and an actual value of the physiological parameter at a particular blood pressure value of the first physiological signal. The processing circuitry is configured to determine, based on a difference between the actual value and the expected value, and store, in the memory, a second relationship between the blood pressure and the physiological parameter, the second relationship being indicative of a change in the cerebral autoregulation of the patient from the first relationship.

Abstract: An apparatus for estimating bio-information may include: a bio-signal acquirer configured to acquire a bio-signal; and a processor configured to extract one or more first feature values from the bio-signal, determine a scale factor based on the first feature values, and to estimate bio-information based on the scale factor and the first feature values.

Abstract: A system for monitoring blood distribution in a subject, the system comprising a processor(38) responsive to Doppler ultrasound data representing arterial blood flow in at least two different locations of the subject, such as the neck and the arm, to obtain velocity (C, B1, B2, B3) or volumetric flow rate at each location, to monitor changes in a predetermined function of the blood flows, and to provide an output indicative of the monitored changes which may result from blood volume centralization. This can indicate the onset of hypovolemia or hypervolemia.

Abstract: A system and method for measuring vital signs and motion from a patient comprising a plurality of sensors, each comprising a processor and analog-to-digital converter configured to generate the physiologic data waveform(s) from the sensor as synchronized, separately resolvable digital data comprising a header indicating the sensor from which the digital data originates, and to transmit the physiologic data waveform(s) to a processing system via a cable comprising a terminal connector that reversibly mates with one of a plurality functionally equivalent of connectors to operably connect the sensor to the processing system. The processing system receive sthe physiologic data waveforms and determines therefrom one or more vital signs for the individual, which are transmitted to a remote vital sign monitor.

Abstract: A medical network service can replace or supplement some or all of an expensive internally staffed clinical facility network with a cloud-based networking service. The medical network service in certain embodiments can provide networking services via software as a service technologies, platform as a service technologies, and/or infrastructure as a service technologies. The medical network service can provide these services to large existing clinical facilities such as metropolitan hospitals as well as to smaller clinical facilities such as specialized surgical centers. The medical network service can replace and/or supplement existing IT networks in hospitals and other clinical facilities and can therefore reduce costs and increase security and reliability of those networks. In addition, the medical network service can provide synergistic benefits that can improve patient outcomes and patient care.

Abstract: Computer based systems and methods for estimating a user state are disclosed. In some embodiments, the methods comprise inputting a first input at an intermittent interval and a second input at a frequent interval into a user state estimation model to estimate the user state. In some embodiments, the first inputs are enhanced by injecting a noise input to create a plurality of enhanced first inputs whereby the plurality of enhance first inputs correspond to the plurality of second inputs at the frequent interval. In some embodiments, the first input comprises a self-reported input and the second inputs comprise a physiological input, a performance input or a situational input. In some embodiments, a machine learning algorithm creates the state estimation model. In some embodiments, the state estimation model estimates a future user state. In some embodiments, a computer based system for estimating a user state is provided.

Abstract: Systems and methods to determine a composite respiration phase of a patient are disclosed, including a signal receiver circuit to receive first and second physiologic information of a patient, and an assessment circuit to determine first respiration phase information of the first physiologic information and to determine the composite respiration phase of the patient using the determined first respiration phase information and the second physiologic information.

Abstract: The present invention discloses a method for determining a maximum value of a heart rate data of a user performing a physical activity. Acquire first heart rate data in a first duration of the physical activity performed by the user. Acquire motion data in the first duration of the physical activity performed by the user. Calculate second heart rate data based on the motion data in the first duration of the physical activity performed by the user by a mathematical model and estimate the maximum value of the heart rate data of the user based on a comparison between the first first heart rate data and the second heart rate data.

Abstract: Systems and methods for monitoring patients for risk of worsening heart failure (WHF) are discussed. A patient management system includes a sensor circuit to receive respiration measurements, and an input device to receive patient dyspnea descriptor indicating dyspnea symptom severity. The system includes a risk analyzer circuit to trend the respiration measurement over time, and to generate a WHF risk indicator using both the trended respiration measurement and the received dyspnea descriptor. A control circuit controls the receiver circuit to receive the dyspnea descriptor in response to the trended respiration measurement satisfying a specific condition. The system can present the WHF risk indicator to a user or a process, or deliver or adjust a HF therapy based on the WHF risk indicator.

Abstract: Systems and methods are disclosed for providing ongoing monitoring and updating of blood volume status, where the system or method can include guidance in the form of recommendations for treatment actions or alerts about altered patient status.

Abstract: An interconnect assembly includes a main body being formed of flexible material and extending between a first end and a second end, the main body having a thickness defined by a top surface and a bottom surface. The interconnect assembly also includes a first connection port located proximate the first end. The interconnect assembly further includes a second connection port located proximate the second end. The interconnect assembly yet further includes a copper trace having a first contact and a second contact, the first contact disposed on the top surface and located adjacent to the first connection port, and the second contact located on the top surface and adjacent to the second connection port.

Abstract: An automated age detection system employing a patient monitoring lead assembly and a patent monitoring device. In operation, the patient monitoring lead assembly conducts electrical activity of a heart of a patient to the patient monitoring device. In response thereto, the patient monitoring device classifying the patient as an adult patient or a pediatric patient as a function of electrocardiogram feature(s) derived from electrocardiogram measurement(s) of the electrical heart activity. The patient monitoring device may further estimate the age as a function of electrocardiogram feature(s). The classification facilitates an appropriate application of an adult analysis or a pediatric analysis of the electrical heart activity.

Abstract: The present specification discloses a neuromodulation system comprising a transcranially mounted neuromodulation device and a stimulation control computing environment. The disclosed neuromodulation device comprising at least one ultrasound transducer and at least one EEG electrode and the disclosed stimulation control computing environment comprises a stimulation control unit and offline computing device, the disclosed stimulation control unit including associated systems and methods for controlling the neuromodulation device functionality using acoustic simulations performed on brain image data as well as methods and uses of such neuromodulation systems in modulating brain activity using focused ultrasound stimulation of the thalamus and thalamic sub regions during certain phases of slow wave brain oscillations in order to treat various neural-based disorders or conditions including sleep disorders.

Abstract: Various embodiments of a pressure sensor assembly and an implantable medical device that includes such assembly are disclosed. The assembly includes a substrate having a via that extends through the substrate along a via axis between a first major surface and a second major surface of the substrate, a membrane disposed on the first major surface of the substrate and over the via, and a patterned metal layer disposed on a first major surface of the membrane, a portion of such layer including a first capacitor plate. The assembly further includes an integrated circuit disposed adjacent to the first major surface of the membrane and electrically connected to the metal layer. The integrated circuit includes a second capacitor plate disposed on or within a substrate of the integrated circuit. The first capacitor plate and the second capacitor plate form a variable capacitor disposed along the via axis.

Abstract: A catheter system for treating a treatment site within or adjacent to a vessel wall or a heart valve includes an energy source, a balloon, an energy guide, and an electrical analyzer assembly. The energy source generates energy. The balloon is positionable substantially adjacent to the treatment site. The balloon has a balloon wall that defines a balloon interior that receives a balloon fluid. The energy guide is configured to receive energy from the energy source and guide the energy into the balloon interior. The electrical analyzer assembly is configured to monitor a balloon condition during use of the catheter system. The electrical analyzer assembly can include a first electrode, a second electrode, and an impedance detector that is electrically coupled to the first electrode and the second electrode. The impedance detector is configured to detect impedance between the first electrode and the second electrode.

Abstract: A method and system for contextual heart rate monitoring are disclosed. In a first aspect, the method comprises calculating a heart rate using a detected ECG signal and detecting an activity level. In a second aspect, the system comprises a wireless sensor device coupled to a user via at least one electrode, wherein the wireless sensor device includes a processor and a memory device coupled to the processor, wherein the memory device stores an application which, when executed by the processor, causes the processor to calculate a heart rate using a detected ECG signal and to detect an activity level.

Abstract: A catheter system and method for treating a treatment site within or adjacent to a vessel wall or a heart valve within a body of a patient includes an energy source, an inflatable balloon, an energy guide, and an acoustic sensor. The inflatable balloon is positionable substantially adjacent to the treatment site. The inflatable balloon has a balloon wall that defines a balloon interior that receives a balloon fluid. The energy guide receives energy from the energy source and guides the energy into the balloon interior. The acoustic sensor is positioned outside the body of the patient. The acoustic sensor senses acoustic sound waves generated in the balloon fluid within the balloon interior. The acoustic sensor generates a sensor signal based at least in part on the sensed acoustic sound waves.

Abstract: A method and system for providing health-monitoring alarm management have been disclosed. In a first aspect, the method comprises detecting at least one vital sign signal using a wearable sensor device and managing an alarm mechanism of the wearable sensor device based on the at least one vital sign signal. In a second aspect, the system comprises a sensor for detecting at least one vital sign signal, a processor coupled to the sensor, and a memory device coupled to the processor, wherein the memory device stores an application which, when executed by the processor, causes the processor to manage an alarm mechanism of the wearable sensor device based on the at least one vital sign signal.

Abstract: A weight management system for managing vehicle seat occupant body weight by using vehicle cameras and weight sensors of a plurality of vehicles having onboard communication modules. Each vehicle is equipped to analyze and compare weight changes of the vehicle seat occupant over time. Based on the weight status, a weight management recommendation can be transmitted to the vehicle seat occupant. Each vehicle is operatively connected to a weight management application in a data center. The weight management application includes a registration module which registers each vehicle. Additionally, a vehicle seat occupant may register with the weight management application to have his/her weight analyzed when travelling in any of the plurality of vehicles. The weight management application requests a search of a data lake and analysis of search results by a weight data artificial intelligence analytics program to improve the weight management recommendation.

Abstract: Implementations illustrated herein discloses a method of controlling drug titration to a patient, the method including receiving, using a processor, a sequence of depth images, each depth image including depth information for at least a portion of the patient, determining, using the processor, a sequence of physiological signals for the patient based on the sequence of depth images, analyzing, using the processor, the sequence of physiological signals for the patient to determine a change in a condition of the patient, and generating a signal to a drug infusion pump in response to determining the change in the condition of the patient.

Abstract: Using aggregate activity data to generate a grade adjusted pace model is disclosed, including: receiving a plurality of activities; selecting a portion of the plurality of activities based at least in part on recorded heart rate information associated with the plurality of activities; and generating a Grade Adjusted Pace (GAP) model based at least in part on the selected portion of the plurality of activities.

Abstract: Methods and systems for treating epilepsy by stimulating a cranial nerve and administering to the patient a responsiveness test and comparing a result of the responsiveness test to a baseline responsiveness test and initiating a second therapy or issuing a warning based on the comparison of the result of the responsiveness test to the baseline responsiveness test.

Abstract: A congenital heart disease monitor utilizes a sensor capable of emitting multiple wavelengths of optical radiation into a tissue site and detecting the optical radiation after attenuation by pulsatile blood flowing within the tissue site. A patient monitor is capable of receiving a sensor signal corresponding to the detected optical radiation and calculating at least one physiological parameter in response. The physiological parameter is measured at a baseline site and a comparison site and a difference in these measurements is calculated. A potential congenital heart disease condition in indicated according to the measured physiological parameter at each of the sites or the calculated difference in the measured physiological parameter between the sites or both.

Abstract: A biological information measuring apparatus includes a detector, a measuring unit, a calculator, and a determining unit. The detector detects pulse waves continuously. The measuring unit measures first biological information. The calculator calculates second biological information from the pulse waves based on the first biological information. The measuring unit suspends the measurement and resumes the measurement after a lapse of a period in a case where the determining unit does not determine that the result of measurement is normal, and the measuring unit continues the measurement in other cases where the body motion is not generated, the pulse waves are not irregular or the blood pressure value fails to vary.

Abstract: Systems and methods for detecting worsening cardiac conditions such as worsening heart failure events are described. A system may include sensor circuits to sense physiological signals and signal processors to generate from the physiological signals first and second signal metrics. The system may include a risk stratifier circuit to produce a cardiac risk indication. The system may use at least the first signal metric to generate a primary detection indication, and use at least the second signal metric and the risk indication to generate a secondary detection indication. The risk indication may be used to modulate the second signal metric. A detector circuit may detect the worsening cardiac event using the primary and secondary detection indications.

Abstract: A gripping force measurement device includes a body portion and a plurality of pressure sensors. The plurality of pressure sensors includes at least one first sensor and two or more second sensors including pressure-sensitive surfaces oriented in the same direction. A pressure-sensitive surface of the first sensor and the pressure-sensitive surfaces of the two or more second sensors are disposed such that, when a subject pressurizes the pressure-sensitive surface of the first sensor and the pressure-sensitive surfaces of the two or more second sensors, the gripping force measurement device is grippable by the subject.

Abstract: Methods and systems for sensor fusion as a service include receiving a sensor fusion intent descriptive of desired data from a specified environment; determining candidate sensors present in the specified environment that may be used to obtain at least a portion of the desired data; and transforming the sensor fusion intent into a sensor fusion manifest by selecting a plurality of the candidate sensors to obtain respective output data, and by defining at least one action to fuse the respective output data into the desired data, wherein the sensor fusion manifest includes an identification of the selected candidate sensors and the at least one action to fuse the respective output data from the selected candidate sensors into the desired data.

Abstract: This document presents a system and method for presenting vetted and verified Supplier information to Buyers. The Know Your Suppler (TYS) Application collects previously vetted and verified Supplier information and commits the collected information, verification authorities, verification details, and transaction information to a shared distributed ledger implemented as a privately permissioned blockchain. Buyers who want to onboard a newly identified Supplier, or update Supplier information with more recently verified information records, may subscribe to the TYS Application and purchase available vetted and verified Supplier information to optimize the onboarding or updating process for Suppliers from whom the Buyer wants to purchase goods or services.

Abstract: Disclosed are methods, apparatuses, and systems for performing physiological parameter signal fusion. By respectively analyzing a plurality of input physiological parameter signals, and obtaining a feature of each physiological parameter signal; according to the feature of each physiological parameter signal, obtaining and outputting a fusion state of the plurality of the physiological parameter signals; if the fusion state is a fusion of the at least two physiological parameter signals with the first physiological parameter signal is dominant, highlighting the first physiological parameter signal; and if the fusion state is a fusion of the at least two physiological parameter signals with the second physiological parameter signal is dominant, highlighting the second physiological parameter signal.

Abstract: A medical system is disclosed. The medical system can include a patient monitoring device, a patient information system, and a mobile application. The patient monitoring device can be coupled to a patient to monitor one or more physiological parameters. The patient information system can allow the patient to communicate with a clinician. The patient information system can also provide information regarding schedules, medications, and procedures to the patient. The mobile application can be communicatively coupled with the patient monitoring device and the patient information system. The mobile application can allow a clinician to receive, view, and send information to or from the patient monitoring device and the patient information system.

Abstract: A conformal patch device can be provided to a patient. The patch device can include sensors configured to be positioned over a chest of a patient. The sensors can include PPG sensors, ECG sensors, and SCG sensors. The conformal patch device can to adhere to a single continuous area of the chest. Some sensors may attached to a viscoelastic substrate to achieve mechanical isolation from other patch components. The conformal patch device can capture measurements from the sensor doing a time window sufficient enough to detect disordered breathing. The system can determine disordered breathing and related cardiorespiratory parameters during the time window for the patient using the sensor measurements.

Abstract: A method and systems for determining an early warning score for a health status of a patient are provided. An example method includes acquiring, during a predetermined time period via sensors integrated into a wearable device worn on a wrist of the patient, initial values of medical parameters of patient. The medical parameters include a respiratory rate, oxygen saturation, temperature, blood pressure, and pulse rate, and level of consciousness. The method includes determining, based on the initial values, normal values of the medical parameters. The method includes acquiring, via the sensors and at a pre-determined frequency, further values of the medical parameters. The method includes determining, based on deviations of the further values from the normal values, individual scores for the medical parameters. The method includes calculating, based on the individual scores, a general score. The method includes determining, based on the general score, the health status of the patient.

Abstract: An actuation device includes a controller that interfaces with a sensing module to cause the sensing module to be non-responsive to events of a class that exceed the threshold level of detectability. The controller may be triggered by a corresponding sensor interface to switch the sensing module to be responsive to events of the class that exceed the threshold level of detectability.

Abstract: Methods and apparatuses for athletic training optimization are disclosed. In one example, a fitness level change is identified. In one example, a current training intensity is updated to reflect an updated user fitness level.

Abstract: A system, computer program product and method for facilitating concurrent monitoring of multiple obstetrics patients over a data network are proposed. Data conveying pregnancy progression information, including maternal and fetal vital sign information associated with the obstetrics patients, is received and processed to derive criticality levels for the obstetrics patients. As a first feature, notification data related to a particular obstetrics patient may be selectively transmitted to a medical expert based on different conditions including for example an associated criticality level exceeding a threshold and/or receipt of a consultation request. As a second feature, used together or separately from the first, a graphical user interface (GUI) may present a user with an ordered list of obstetrics patients dynamically adaptable based on the criticality levels.

Abstract: A monitor configured to monitor autoregulation includes a memory encoding one or more processor-executable routines and a processor configured to access and execute the one or more routines encoded by the memory. When executed, the routines cause the processor to receive one or more physiological signals from a patient, determine a measure indicative of an autoregulation status of the patient based on the one or more physiological signals, generate an autoregulation alarm indicative of an impaired autoregulation status when the measure exceeds a predetermined threshold for more than a predetermined period of time.

Abstract: An image forming apparatus includes an image processing device, an image forming device, an operating device, a vital sensor, and a controller. The image processing device corrects an image. The image forming device performs an image formation of forming the image on a recording sheet. The operating device is operable by a user and through which an instruction to start the image formation by the image forming device is inputted. The vital sensor is provided at the operating device and detects a blood oxygen level of the user who is operating the operating device. The controller, when the instruction to start the image formation is inputted through the operating device, causes the image processing device to correct the image in accordance with the blood oxygen level of the user detected by the vital sensor and causes the image forming device to form a corrected image on the recording sheet.

Abstract: The embodiments herein provide a system for calibration-free cuff-less evaluation of blood pressure. The system includes an ultrasound-based arterial compliance probes and a controller unit connected to the said probe. The ultrasound transducers are configured to measure the change in arterial dimensions, pulse wave velocity, and other character traits of an arterial segment over continuous cardiac cycle, which is then used to evaluate blood pressure parameters without any calibration procedure using dedicated mathematical models.

Abstract: Disclosed is an apparatus for determining viscoelastic characteristics of at least a portion of an object. The apparatus comprises a fluidly sealable housing, comprising at least one aperture and at least one fluid inlet port and at least one resilient membrane that is operatively coupled to the housing so as to sealingly engage with the at least one aperture. The apparatus further comprises at least one actuator that is operatively coupled to the at least one inlet port and adapted to actuate the at least one resilient membrane via a working fluid that is contained within the housing, so that the at least one resilient membrane is moved towards and into engagement with at least a portion of an object at a predetermined pressure. Furthermore, the apparatus comprises at least one first sensor that is operably coupled to the membrane and that is adapted to determine at least a deformation of the at least one resilient membrane during actuation.

Abstract: The invention comprises a method and apparatus for estimating state of a cardiovascular system, comprising a cardiac stroke volume analyzer, comprising: (1) a blood pressure sensor generating a time-varying pressure state waveform output from a limb of the person; (2) a system processor connected to the blood pressure sensor; and (3) a dynamic state-space model; the system processor receiving cardiovascular input data, from the blood pressure sensor, related to a transient pressure state of the cardiovascular system; at least one probabilistic model, of the dynamic state-space model, operating on the time-varying pressure state waveform output to generate a probability distribution function to a non-pressure state of the cardiovascular system; iteratively updating the probability distribution function using output from the blood pressure sensor; and processing the probability distribution function to generate a non-pressure state output related to stroke volume of a heart of the person and arterial compliance

Abstract: A method for measuring an intracranial bioimpedance in a patient's head, to help evaluate cerebral autoregulation, may involve securing a volumetric integral phase-shift spectroscopy (VIPS) device to the patient's head, measuring the intracranial bioimpedance with the VIPS device by measuring a phase shift between a magnetic field transmitted from a transmitter on one side of a VIPS device and a magnetic field received at a receiver on another side of the VIPS device, at one or more frequencies, and evaluating cerebral autoregulation in the intracranial bioimpedance, using a processor in the VIPS device.

Abstract: A display panel is disclosed, the display array including: a substrate; a functional layer on the substrate having a plurality of recesses, at least one of the recesses in a sub-pixel region forming a well structure with a sidewall formed of the functional layer and a bottom formed of the substrate; and a plurality of micro light emitting diodes (Micro LEDs) for emitting light, at least one of the Micro LEDs within a corresponding recess; wherein the functional layer is configured to prevent at least part of the light emitted by one of the Micro LEDs and incident on the sidewall of the corresponding recess from being subsequently emitted through an adjacent sub-pixel region.

Abstract: An artificial intelligence-based interference recognition method for an electrocardiogram, comprising: cutting and sampling heart beat data of a first data amount, and inputting the heart beat data to be recognized that is obtained by cutting and sampling into an interference recognition binary classification model for interference recognition; in a sequence of the heart beat data, performing signal anomaly determination on a heart beat data segment where an inter-beat interval is greater than or equal to a preset interval determination threshold value, so as to determine whether the heart beat data segment is an abnormal signal; if the heart beat data segment is not an abnormal signal, determining a starting data point and an ending data point of sliding sampling in the heart beat data segment according to a set time with a preset time width, and performing sliding sampling on the data segment from the starting data point until the ending data point so as to obtain multiple sampling data segments; and using

Abstract: A computer-implemented method includes providing, by at least one computer processor, a plurality of signal channels, wherein the plurality of signal channels includes a plurality of electrical uterine monitoring signal channels and a plurality of acoustic uterine monitoring signal channels; determining, by the at least one computer processor, a plurality of channel weights, wherein each of the channel weights corresponds to a particular one of the signal channels; and generating, by the at least one computer processor, a combined uterine monitoring signal channel by calculating a weighted average of the signal channels based on the channel weight for each of the signal channels.

Abstract: A dressing assembly for providing a warning to a patient or caregiver that the patient needs attention. The dressing assembly is adapted to be applied to or near a surface of the patient's body and generate electrical outputs corresponding to soft tissue pressure and other health characteristics sensed at the surface. The dressing assembly includes a pocket formed therein for removable, secured and protected insertion of a variety of different sensors such as multiple pressure sensors.

Abstract: A method to identify feature points associated with the heart valve movement, heart contraction or cardiac hemodynamics is revealed. The mechanocardiography (MCG) is a technology that makes use of vibrational waveforms acquired using at least one gravity sensor attached on one of the four heart valve auscultation sites on the body surface. The data of the electrocardiography (ECG) is recorded simultaneously with the MCG The feature points are identified by comparing P, R and T points of synchronized ECG with the MCG spectrum. By the time sequences and amplitudes of the feature points, the method provides additional clinical information of cardiac cycle abnormalities for diagnosis.

Abstract: An abnormal respiration detection apparatus includes a sensor for sensing a PPG signal from an optical signal reflected and received from a user's body; a band pass filter for extracting a signal of a required band from the PPG signal; an analog-to-digital converter for performing a digital conversion on the filtered PPG signal; and an abnormal respiration recognition unit deriving a respiration rate signal from the digital-converted PPG signal, deriving a plurality of respiration rate characteristic values through a time axis analysis on the derived respiration rate signal, and detecting an abnormal respiration using the derived plurality of respiration rate characteristic values. The embodiments can be utilized to monitor the survival of elders who live alone, soldiers isolated in a military operation, persons isolated in disaster and accident sites, thereby contributing to public and social safety and building of welfare society and nation.

Abstract: An apparatus for estimating blood pressure is provided. The apparatus for estimating blood pressure may include: a bio-signal measurer configured to measure a bio-signal from a user; and a processor configured to extract one or more feature values from the bio-signal, to adjust a combination coefficient for combining the one or more feature values based on a reference value associated with vascular compliance, and to estimate blood pressure based on the adjusted combination coefficient, and the one or more feature values extracted from the bio-signal.

Abstract: A device for non-invasive monitoring of intracranial pressure (ICP) may include a sensor, a processor unit, a device for recording electrical activity of the heart, and a device for invasive measurement of arterial blood pressure. The sensor monitors mechanical movements caused by bloodstream dynamics. A mathematical model and a relation between the start of a R-wave and a time delay of a mechanical movement of a patient's head are used to determine the ICP. A device for monitoring patient's vital functions may also measure respiratory and heart rate. The sensor may employ a piezoelectric transducer, which may form a measuring electrode of a measuring capacitor. In addition, a comparator capacitor may be used to increase resistance in changes in measuring conditions. Data from a plurality of measuring devices may be collected and processed in a cascading manner.