Testing Artificially Regulated Or Assisted Heart Patents (Class 600/510)
  • Patent number: 8731647
    Abstract: This method for analyzing the cardiac activity of a patient are comprises the steps for acquiring (20) at least one cardiac said electric signal comprising at least one elementary signal corresponding to a heart beat, for extracting (29) from said elementary signal, at least one elementary wave, the general shape of which may be expressed by x(t)=x0+x1 cos(?(t)), wherein ?(t) is the phase of said elementary wave, and for analyzing (30) said elementary wave, comprising the steps for determining an expression of a phase equation F ? ( ? ) = ? ? ? t of said elementary wave and determining an expression of the phase ?(t) of said elementary wave as a functions of parameters measuring the anharmonicity of said elementary wave and its morphology, from p cosn and p sinn functions defined by: p ? ? cos n ? ( t , r ) = ? k = 1 ? ? cos ? ( kt ) ? r k k n ? ? and ? ? p ? ? sin n ? ( t , r ) = ? k = 1 ? ? sin ? ( kt ) ? r k k n .
    Type: Grant
    Filed: April 12, 2011
    Date of Patent: May 20, 2014
    Assignee: Centre National de la Recherche Scientifique (C.N.R.S)
    Inventor: Patrick Hanusse
  • Publication number: 20140135638
    Abstract: Electrodes and circuitry for monitoring and stimulating the exterior of the human body, comprising delivering stimulation pulses to stimulation electrodes applied to the exterior of the body, detecting an electrical potential at monitoring electrodes applied to the exterior of the body, positioning at least a first and second monitoring electrode at locations at which an electrical artifact caused by the electrical stimulation pulses is substantially cancelled in a signal formed from the electrical potentials detected at the first and second monitoring electrodes.
    Type: Application
    Filed: January 16, 2014
    Publication date: May 15, 2014
    Applicant: ZOLL Medical Corporation
    Inventors: Daniel M. Lisogurski, Frederick J. Geheb, Michael R. Dupelle, Gary A. Freeman, Martin E. Bures, Gideon D. H. Butler, David N. Craige, III, Marc Cordaro, Deborah T. Jones, Michael Lopin, Michael Parascandola
  • Patent number: 8712524
    Abstract: A self-diagnostic system for an implantable cardiac device such as a pacemaker, cardioverter, or resynchronization device which utilizes a subcutaneous ECG channel is described. The subcutaneous ECG channel allows the device to, in real time and independent of the standard pacing and sensing circuitry, verify the presence of pacing spikes, chamber senses, and other device outputs and hence establish and verify device integrity.
    Type: Grant
    Filed: July 2, 2010
    Date of Patent: April 29, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Aaron R. McCabe, David J. Yonce
  • Publication number: 20140114203
    Abstract: Techniques are provided for use by implantable medical devices such as pacemakers or by external systems in communication with such devices. An intracardiac electrogram (IEGM) is sensed within a patient in which the device is implanted using a cardiac signal sensing system. Cardiac events of interest such as arrhythmias, premature atrial contractions (PACs), premature ventricular contractions (PVCs) and pacemaker mediated tachycardias (PMTs) are detected within the patient using event detection systems and then portions of the IEGM representative of the events of interest are recorded in device memory. Subsequently, during an off-line or background analysis, the recorded IEGM data is retrieved and analyzed to identify false detections. In response to false detections, the cardiac signal sensing systems and/or the event detection systems of the implantable device are selectively adjusted or reprogrammed to reduce or eliminate any further false detections, including false-positives or false-negatives.
    Type: Application
    Filed: December 20, 2013
    Publication date: April 24, 2014
    Applicant: PACESETTER, INC.
    Inventors: Jeffery D. Snell, Euljoon Park
  • Patent number: 8700139
    Abstract: A late potential detecting system has an implantable medical device connected to at least one cardiac lead having implantable electrodes positioned at different sites of a ventricle myocardium. A sampling unit of the implantable medical device records electrogram samples for the different implantable electrodes to get different sample sets. The electrogram samples of the sample sets are time synchronized and magnitude potential representations of the potential data of the electrogram samples are determined. The magnitude potential representations of the time synchronized electrogram samples are then co-processed and used for determining a parameter that is indicative of any late potentials of the monitored ventricle.
    Type: Grant
    Filed: June 26, 2009
    Date of Patent: April 15, 2014
    Assignee: St. Jude Medical AB
    Inventor: Andreas Blomqvist
  • Publication number: 20140094708
    Abstract: An apparatus for determining a possibility of return of spontaneous circulation, includes: an electrocardiogram acquiring unit acquiring electrocardiogram waveform data from a subject in a cardiac arrest condition during chest compression applied to the subject; a bandpass filter unit allowing only a frequency component in a vicinity of a frequency of a P wave of the electrocardiogram waveform to pass through the bandpass filter unit; a resuscitation possibility determining unit determining whether an output of the bandpass filter unit exceeds a predetermined value or not, and determining that there is the possibility of return of spontaneous circulation when the output exceeds the predetermined value; and an outputting unit outputting a result of determination related to the possibility of return of spontaneous circulation.
    Type: Application
    Filed: October 2, 2013
    Publication date: April 3, 2014
    Applicants: Tokyo Medical University, NIHON KOHDEN CORPORATION
    Inventors: Shinya Nagata, Jun Oda
  • Patent number: 8682428
    Abstract: A method for operating an implantable medical device to obtain substantially synchronized closure of the mitral and tricuspid valves based on sensed heart sounds includes sensing an acoustic energy; producing signals indicative of heart sounds of the heart of the patient over predetermined periods of a cardiac cycle during successive cardiac cycles; calculating a pulse width of such a signal; and iteratively controlling a delivery of the ventricular pacing pulses based on calculated pulse widths of successive heart sound signals to identify an RV interval or VV interval that causes a substantially synchronized closure of the mitral and tricuspid valve. A medical device for optimizing an RV interval or VV interval based on sensed heart sounds implements such a method and a computer readable medium encoded with instructions causes a computer to perform such a method.
    Type: Grant
    Filed: November 30, 2005
    Date of Patent: March 25, 2014
    Assignee: St. Jude Medical AB
    Inventors: Nils Holmström, Kjell Noren
  • Patent number: 8682432
    Abstract: Provided is a cardiac-event processor (1) including a storing unit (11) that stores a time history of cardiac events, including heartbeats, in association with the presence/absence of nerve stimulation; a heart rate calculator (12) that calculates a heart rate for when each heartbeat is detected, on the basis of the time history of the cardiac events stored in the storing unit (11); and a frequency data generator (13) that separately adds up frequencies of the heart rates calculated by the heart rate calculator (12) for the cases with and without the nerve stimulation.
    Type: Grant
    Filed: September 17, 2010
    Date of Patent: March 25, 2014
    Assignee: Olympus Corporation
    Inventor: Keiichiro Nakajima
  • Patent number: 8676289
    Abstract: A method of detecting cardiac signals in a medical device that includes decomposing a cardiac signal using a wavelet function at a plurality of scales to form a corresponding wavelet transform, determining approximation coefficients in response to the plurality of scales, reconstructing a first wavelet representation of the wavelet transform using predetermined approximation coefficients of the determined approximation coefficients, and evaluating the detected cardiac signals in response to the reconstructing.
    Type: Grant
    Filed: May 4, 2007
    Date of Patent: March 18, 2014
    Assignee: Medtronic, Inc.
    Inventors: Raja N. Ghanem, Troy E. Jackson
  • Patent number: 8676305
    Abstract: A method for mapping abnormal electrical activity, including obtaining electrical signal data from respective locations in a heart of a living subject, and automatically analyzing the signal data to identify complex fractionated electrograms (CFEs) therein. The method further includes analyzing the CFEs so as to identify reentry locations comprised in the respective locations, and displaying information derived from the identification in relation to a map of the heart.
    Type: Grant
    Filed: March 21, 2012
    Date of Patent: March 18, 2014
    Assignee: Biosense Webster (Israel) Ltd.
    Inventors: Gal Hayam, Limor Elran, Aharon Turgeman, Yaariv Khaykin
  • Publication number: 20140073894
    Abstract: An active medical device using non-linear filtering for the reconstruction of a surface electrocardiogram (ECG) from an endocardial electrogram (EGM) is disclosed. The device for the reconstruction of the surface ECG comprises: a plurality of inputs, receiving a corresponding plurality of EGM signals from endocardial or epicardial electrogram (x1[n], x2[n]), each collected on a respective EGM derivation of a plurality of EGM derivations, and at least one output delivering a reconstructed surface ECG electrocardiogram signal (y[n]), related to an ECG derivation, and a non-linear digital filter (12?, 12?, 14) with a transfer function that determines the reconstructed ECG signal based on said plurality of input EGM signals. The non-linear digital filter includes a Volterra filter type (12, 12?, 12?) whose transfer function includes a linear term (h1) and at least one quadratic (h2) and/or cubic (h3) term(s).
    Type: Application
    Filed: September 9, 2013
    Publication date: March 13, 2014
    Applicant: SORIN CRM S.A.S.
    Inventor: Alaa Makdissi
  • Publication number: 20140046204
    Abstract: Methods, systems, and devices for signal analysis in an implanted cardiac monitoring and treatment device such as an implantable cardioverter defibrillator. In illustrative examples, captured data including detected events is analyzed to identify likely overdetection of cardiac events. In some illustrative examples, when overdetection is identified, data may be modified to correct for overdetection, to reduce the impact of overdetection, or to ignore overdetected data. New methods for organizing the use of morphology and rate analysis in an overall architecture for rhythm classification and cardiac signal analysis are also discussed.
    Type: Application
    Filed: October 18, 2013
    Publication date: February 13, 2014
    Applicant: Cameron Health, Inc.
    Inventors: Venugopal Allavatam, Surekha Palreddy, Rick Sanghera, Jay A. Warren
  • Publication number: 20140039333
    Abstract: Techniques are provided for use with an implantable medical device for evaluating mechanical cardiac dyssynchrony based impedance (Z) measured along different vectors between an electrode in the right ventricle (RV) and various electrodes of a multi-pole left ventricle (LV) lead.
    Type: Application
    Filed: July 31, 2012
    Publication date: February 6, 2014
    Applicant: PACESETTER, INC.
    Inventor: Xiaoyi Min
  • Publication number: 20140039334
    Abstract: The invention provides a system for evaluating a patient featuring: 1) an ECG-measuring system connected to the patient and configured to sense ECG information from the patient; 2) a data-acquisition system interfaced to a vital sign-monitoring system configured to sense vital sign information from the patient during an electro-physiology (EP) procedure; and 3) an external software system interfaced to both systems. The external software system includes a first software interface that receives ECG information measured from the patient by the ECG-measuring system, and a second software interface that receives vital sign and EP-related information from the data-acquisition system measured from the patient during an EP procedure. A database stores physiological and EP-related information measured from the patient before, during, and after the EP procedure.
    Type: Application
    Filed: July 25, 2013
    Publication date: February 6, 2014
    Inventors: Matthew Banet, Gregory Feld, Andrew Terry
  • Publication number: 20140039332
    Abstract: Methods and systems are provided for discriminating heart arrhythmias. The methods and systems include identifying an arrhythmia, recording a predetermined number of beats during the arrhythmia as a base arrhythmia (BA) beats; delivering anti-tachy pacing (ATP) therapy to at least one chamber of the heart. After delivering the ATP therapy, the methods and system record at least one return beat representing cardiac activity following the ATP therapy, determines whether the return beat originated in a reference chamber of the heart, compares a morphology of the return beat to a morphology of the BA beat; and declares a VT or SVT based on the comparing operation.
    Type: Application
    Filed: July 31, 2012
    Publication date: February 6, 2014
    Applicant: PACESETTER, INC.
    Inventors: Xiaoyi Min, Eliot L. Ostrow
  • Patent number: 8634902
    Abstract: A cardiac analysis system is provided that includes an implantable medical device (IMD), at least one sensor, and an external device. The IMD has electrodes positioned proximate to a heart that sense first cardiac signals of the heart and associated with a clinical ventricular tachycardia (VT) event and second cardiac signals associated with an induced VT event. The sensor measures first and second cardiac parameters of the heart associated with the clinical and induced VT events, respectively. The external device is configured to receive the first and second cardiac signals associated with the clinical and the induced VT events and the first and second cardiac parameters associated with the clinical and the induced VT events. The external device compares the first and second cardiac signals and compares the first and second cardiac parameters to determine if the clinical and induced VT events are a common type of VT event.
    Type: Grant
    Filed: June 22, 2010
    Date of Patent: January 21, 2014
    Assignee: Pacesetter, Inc.
    Inventors: Michael E. Benser, Gene A. Bornzin, Euljoon Park, Kyungmoo Ryu, Michael Hardage
  • Publication number: 20140018688
    Abstract: A medical device and associated method establish an occurrence of a premature atrial contraction. The device senses a ventricular signal. A control unit is configured to determine a metric of the ventricular signal during an interval following the premature atrial contraction and detect a change in cardiac stress tolerance in response to the determined metric.
    Type: Application
    Filed: July 16, 2012
    Publication date: January 16, 2014
    Inventors: Zhendong Song, Xiaohong Zhou
  • Patent number: 8628471
    Abstract: Systems and Methods for predicting patient health and patient relative well-being within a patient management system are disclosed. A preferred embodiment utilizes an implantable medical device comprising an analysis component and a sensing component further comprising a three-dimensional accelerometer, a transthoracic impedance sensor, a cardio-activity sensor, an oxygen saturation sensor and a blood glucose sensor. Some embodiments of a system disclosed herein also can be configured as an Advanced Patient Management System that helps better monitor, predict and manage chronic diseases.
    Type: Grant
    Filed: June 30, 2010
    Date of Patent: January 14, 2014
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Scott T. Mazar, Richard Fogoros, Yatheendhar D. Manicka, Bruce H. KenKnight, Michael J. Pederson
  • Patent number: 8611990
    Abstract: The present invention provides systems, methods and computer program products for monitoring a heart. According to one embodiment, the system includes an implantable registering unit. The registering unit comprises a first controller structured to register an electrical signal from the heart. The system includes a second controller in operable communication with the first controller. The second controller comprises a data repository structured to receive data corresponding to the registered electrical signal and being structured to store the data. The data repository stores data corresponding to a baseline electrical signal of the heart. The second controller is structured to receive the data from the first controller corresponding to the registered electrical signal and to compare the registered electrical signal to the baseline electrical signal to determine whether the heart is functioning properly.
    Type: Grant
    Filed: February 25, 2011
    Date of Patent: December 17, 2013
    Assignee: Lifescience Solutions LLC
    Inventor: Charles L. Richardson
  • Publication number: 20130324868
    Abstract: According to some embodiments, a wearable medical device capable of treating a patient presenting with syncope is provided. The wearable medical device includes a memory storing event profile information, a battery, at least one treatment electrode coupled to the battery, at least one processor coupled to the memory and the at least one treatment electrode, and an event manager executed by the at least one processor. The event manager is configured to detect an event associated with syncope; store, in the memory, data descriptive of the event in association with an indication that the data includes data descriptive of a syncopal event; and address the to event.
    Type: Application
    Filed: May 31, 2013
    Publication date: December 5, 2013
    Applicant: ZOLL MEDICAL CORPORATION
    Inventors: Thomas E. Kaib, Shane S. Volpe, Jason T. Whiting, Gregory R. Frank, Rachel H. Carlson
  • Patent number: 8600504
    Abstract: Physiologic demand driven pacing can be used to maintain cardiac synchrony and improve hemodynamic function in patients with heart failure.
    Type: Grant
    Filed: June 16, 2011
    Date of Patent: December 3, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Donald L. Hopper, Yinghong Yu, David J. Ternes
  • Patent number: 8594775
    Abstract: A method includes retrieving electrogram (EGM) data for N cardiac cycles from a memory of an implantable medical device. N is an integer greater than 1. The method further include categorizing each of the N cardiac cycles into one of a plurality of categories based on a morphology of the N cardiac cycles and performing comparisons between pairs of the N cardiac cycles. Each of the comparisons between two cardiac cycles includes detecting a mismatch between the two cardiac cycles when the two cardiac cycles are in different categories, and detecting a match between the two cardiac cycles when the two cardiac cycles are in the same category. Additionally, the method includes classifying the rhythm of the N cardiac cycles based on a number of detected matches and detected mismatches.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: November 26, 2013
    Assignee: Medtronic, Inc.
    Inventors: Subham Ghosh, Jeffrey M. Gillberg
  • Patent number: 8588894
    Abstract: Techniques include determining a first vector of temporal changes in electrical data measured at multiple electrical sensors positioned at corresponding locations on a surface of a living body due to a natural electrical pulse. A different vector of temporal changes in electrical data measured at the same electrical sensors is determined due to each stimulated signal of multiple stimulated signals within the living body. Stimulated position data is received, which indicates a different corresponding position within the living body where each of the stimulated signals originates. The site of origin of the natural electrical pulse is determined based on the first vector and the multiple different vectors and the stimulated position data. Among other applications, these techniques allow the rapid, automatic determination of the site of origin of ventricular tachycardia arrhythmia (VT).
    Type: Grant
    Filed: September 25, 2008
    Date of Patent: November 19, 2013
    Assignee: University of Maryland, Baltimore
    Inventors: Magdi M. Saba, Stephen R. Shorofsky
  • Publication number: 20130303925
    Abstract: Dual chamber pacemaker systems can lead to two forms of pacemaker-facilitated tachycardia—pacemaker-mediated tachycardia (PMT) and tracking of sinus or atrial tachycardia. Current pacemaker algorithms can not always differentiate between these two tachycardias. Various embodiments for differentiating these particular mechanisms of pacemaker-facilitated tachycardia, which is based on the specific termination response to PVARP extension are provided. The response to PVARP extension (V-A-A-V vs V-A-V) is a specific method for differentiation and can be used in conjunction with observations of atrial rate and electrogram morphology (or surface P wave morphology) for distinguishing between the two mechanisms of pacemaker-facilitated tachycardia.
    Type: Application
    Filed: December 14, 2011
    Publication date: November 14, 2013
    Applicant: CORNELL UNIVERSITY
    Inventors: James E. Ip, Bruce B. Lerman
  • Patent number: 8583219
    Abstract: In a possible implementation, a method for cardiac testing is provided which includes measuring test data associated with cardiac events and storing the test data in an intracardiac stimulation device. The method further includes acquiring event electrograms corresponding with the test data and storing the event electrograms corresponding with the test data in the intracardiac stimulation device. In a possible implementation, marker data is stored associating event electrograms with measured test data, which may identify the event electrograms used for measuring the test data and/or identify when adjacent event electrograms are not contiguous. In some implementations, the test data may be measured and stored in an out-of-clinic test, and the test data and the corresponding event electrograms may be later retrieved from the intracardiac stimulation device and presented on a visual display.
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: November 12, 2013
    Assignee: Pacesetter, Inc.
    Inventors: Jennifer Rhude, Elia A. Mouchawar, David Houck, Gregory Hauck, Tejpal Singh, Monique Prue
  • Publication number: 20130296726
    Abstract: Systems and methods are provided for evaluating an expected effectiveness of cardiac resynchronization therapy. Electrocardiogram (ECG) data is received as at least one ECG lead from a set of electrodes. A frequency spectrum representing the ECG data is generated via a Fourier transform. At least one predictor value is extracted from the calculated frequency spectrum. A fitness parameter, representing the expected effectiveness of cardiac resynchronization, is determined from at least the extracted predictor value.
    Type: Application
    Filed: May 3, 2013
    Publication date: November 7, 2013
    Applicant: THE CLEVELAND CLINIC FOUNDATION
    Inventors: Mark Niebauer, Cristian Pasluosta, Niraj Varma
  • Patent number: 8565865
    Abstract: Methods for determination of timing for electrical shocks to the heart to determine shock strength necessary to defibrillate a fibrillating heart. The timing corresponds the window of most vulnerability in the heart, which occurs during the T-wave of a heartbeat. Using a derivatized T-wave representation, the timing of most vulnerability is determined by a center of the area method, peak amplitude method, width method, or other similar methods. Devices are similarly disclosed embodying the methods of the present disclosure.
    Type: Grant
    Filed: July 24, 2008
    Date of Patent: October 22, 2013
    Assignees: Medtronic, Inc., Imperception, Inc.
    Inventors: Paul A. Belk, Jian Cao, Jeffrey M. Gillberg, Charles D. Swerdlow
  • Patent number: 8560056
    Abstract: In a possible implementation, a method for cardiac testing is provided which includes measuring test data associated with cardiac events and storing the test data in an intracardiac stimulation device. The method further includes acquiring event electrograms corresponding with the test data and storing the event electrograms corresponding with the test data in the intracardiac stimulation device. In a possible implementation, marker data is stored associating event electrograms with measured test data, which may identify the event electrograms used for measuring the test data and/or identify when adjacent event electrograms are not contiguous. In some implementations, the test data may be measured and stored in an out-of-clinic test, and the test data and the corresponding event electrograms may be later retrieved from the intracardiac stimulation device and presented on a visual display.
    Type: Grant
    Filed: August 1, 2012
    Date of Patent: October 15, 2013
    Assignee: Pacesetter, Inc.
    Inventors: Jennifer Rhude, Elia A. Mouchawar, David Houck, Gregory Hauck, Tejpal Singh, Monique Prue
  • Patent number: 8554314
    Abstract: A device and method of detecting the severity of myocardial ischemia and heart attack risk is provided. The method includes obtaining an electrogram signal, determining T-wave measurements based on the electrogram signal, and determining ST segment measurements based on the electrogram signal. The method also includes identifying T-wave alternans based on the T-wave measurements and identifying ST segment changes based on the ST segment measurements. The method further includes correlating the T-wave alternans with the ST segment changes in order to detect a severity of ischemia.
    Type: Grant
    Filed: October 31, 2008
    Date of Patent: October 8, 2013
    Assignee: Medtronic, Inc.
    Inventor: Xiaohong Zhou
  • Publication number: 20130261476
    Abstract: In an example, a system includes a cardiac pulse generator configured to generate cardiac paces to pace the heart, a sensor configured to sense a physiological signal for use in detecting pace-induced phrenic nerve stimulation where the pace-induced phrenic nerve stimulation is phrenic nerve stimulation induced by electrical cardiac pace signals, and a phrenic nerve stimulation detector configured to analyze the sensed physiological signal to detect PS beats where the PS beats are cardiac paces that induce phrenic nerve stimulation. The detector may be configured to correlate signal data for sensed beat signals to a PS template to detect PS beats, or may be configured to analyze morphological features of sensed beat signals to detect PS beats, or may be configured to detect PS beats using a combination that both correlates signal data for sensed beat signals to a PS template and analyzes morphological features of sensed beat signals.
    Type: Application
    Filed: February 28, 2013
    Publication date: October 3, 2013
    Applicant: Cardiac Pacemakers, Inc.
    Inventors: Holly Rockweiler, Sunipa Saha, Yanting Dong
  • Publication number: 20130261471
    Abstract: Some method examples may include pacing a heart with cardiac paces, sensing a physiological signal for use in detecting pace-induced phrenic nerve stimulation, performing a baseline level determination process to identify a baseline level for the sensed physiological signal, and detecting pace-induced phrenic nerve stimulation using the sensed physiological signal and the calculated baseline level. Detecting pace-induced phrenic nerve stimulation may include sampling the sensed physiological signal during each of a plurality of cardiac cycles to provide sampled signals and calculating the baseline level for the physiological signal using the sampled signals. Sampling the sensed physiological signal may include sampling the signal during a time window defined using a pace time with each of the cardiac cycles to avoid cardiac components and phrenic nerve stimulation components in the sampled signal.
    Type: Application
    Filed: February 28, 2013
    Publication date: October 3, 2013
    Applicant: Cardiac Pacemakers, Inc.
    Inventors: Sunipa Saha, Yanting Dong, Holly Rockweiler
  • Publication number: 20130261473
    Abstract: Methods, systems and devices efficiently identify cardiac resynchronization therapy (CRT) pacing parameter set(s) that provide improved hemodynamic response relative to an initial CRT pacing parameter set, wherein each CRT pacing parameter set includes at least two CRT pacing parameters. User input(s) are accepted that specify a maximum amount of time and/or parameter sets that can be used to perform testing, and specify relative importance of parameters within the sets. Based on the accepted user input(s), there is a determination of how many different variations of each of the CRT pacing parameters can be tested, and based on this determination different CRT pacing parameter sets are selected and tested to obtain a hemodynamic response measure corresponding to each of the different sets tested. Additionally, one or more of the tested CRT pacing parameter sets, if any, that provide improved hemodynamic response relative to the initial CRT pacing parameter set is/are identified.
    Type: Application
    Filed: March 28, 2012
    Publication date: October 3, 2013
    Inventors: Cecilia Qin Xi, Yasser Sowb
  • Patent number: 8548576
    Abstract: A system and method for correlating health related data for display. The system includes a medical device recording data and a display producing device which correlates the data and simultaneously displays different types of data or displays two sets of the same type of data along with the circumstances at which the two sets of data were recorded. Such displays aid a physician in prescribing and ascertaining the efficacy of cardiac therapies.
    Type: Grant
    Filed: March 2, 2012
    Date of Patent: October 1, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: James Kalgren, Rene H. Wentkowski, Jeffrey E. Stahmann
  • Patent number: 8532762
    Abstract: Cardiac arrhythmias are classified based on the morphology of the arrhythmia episode beats. Templates are formed using morphological features of the cardiac beats of the episode. The arrhythmia episode is classified as a monomorphic tachyarrhythmia or polymorphic tachyarrhythmia based on the one or more templates. The arrhythmia episode may be classified based on a number templates formed from the arrhythmia episode. The templates are formed by determining a measure of similarity between morphological features of a cardiac beat to a template. The similarities can be determined based on a pairing rule that determines which beat morphologies are compared. Selection of therapy for treating the arrhythmia episode may depend on the historical success of a therapy at mitigating previous arrhythmias of the same type as the arrhythmia episode.
    Type: Grant
    Filed: December 20, 2005
    Date of Patent: September 10, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Shelley Cazares, Carlos Ricci, Dan Li, Yayun Lin, Yi Zhang, Jaeho Kim, Joseph Bocek
  • Patent number: 8512256
    Abstract: A method of locating a tip of a central venous catheter (“CVC”) having a distal and proximal pair of electrodes disposed within the superior vena cava, right atrium, and/or right ventricle. The method includes obtaining a distal and proximal electrical signal from the distal and proximal pair of electrodes and using those signals to generate a distal and proximal P wave, respectively. A deflection value is determined for each of the P waves. A ratio of the deflection values is then used to determine a location of the tip of the CVC. Optionally, the CVC may include a reference pair of electrodes disposed within the superior vena cava from which a reference deflection value may be obtained. A ratio of one of the other deflection values to the reference deflection value may be used to determine the location of the tip of the CVC.
    Type: Grant
    Filed: September 9, 2010
    Date of Patent: August 20, 2013
    Assignee: Bard Access Systems, Inc.
    Inventor: Peter M. Rothenberg
  • Patent number: 8467863
    Abstract: A sensing apparatus for sensing an object includes an arrangement of sensing elements for sensing a property of the object. The sensing elements are operable in a contact mode, in which a sensing is performable, while the sensing elements are in contact with the object, and in a non-contact mode, in which a sensing is performable, while the sensing elements are not in contact with the object. The sensing apparatus further includes a mode determination unit for determining whether or not a sensing element is in contact with the object.
    Type: Grant
    Filed: August 20, 2009
    Date of Patent: June 18, 2013
    Assignee: Koninklijke Philips N.V.
    Inventors: Joachim Kahlert, Maya Ella Barley
  • Patent number: 8463369
    Abstract: Systems, devices, structures, and methods are provided to present a visual display based on data from an implantable medical device. The display includes a chart showing the frequency of a detected type of arrhythmia over a predetermined period of time.
    Type: Grant
    Filed: June 13, 2011
    Date of Patent: June 11, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Vickie L. Conley, Allan T. Koshiol
  • Publication number: 20130138004
    Abstract: A system and method for performing independent, off-line evaluation of event sensing for collected electrograms, comprising: sensing an electrogram using an implantable medical device (IMD); determining locations of heart beats on at least one channel of the electrogram using a multi-pass process, resulting in a group of multi-pass beat locations; storing the electrogram and device-identified beat locations in a memory location; and retrieving the electrogram and device-identified beat locations from the memory location. The multi-pass process determines locations of heart beats on at least a first channel of the electrogram. The device-identified group of beat locations are then compared to the multi-pass group of beat locations identified using the multi-pass method. Based on the comparing step, oversensing of beats, undersensing of beats, or noise from the device can be detected.
    Type: Application
    Filed: May 30, 2012
    Publication date: May 30, 2013
    Applicant: CARDIAC PACEMAKERS, INC.
    Inventors: Yanting Dong, Shijie Zhang, Deepa Mahajan, Chenguang Liu, Dan Li, Yayun Lin, Derek D. Bohn
  • Patent number: 8452404
    Abstract: A device for detecting cardiac ischemia is disclosed. The device includes a processor that is configured to operate in three different modes according to relative frequency of different beat types. If beats of a first beat type, such as ventricularly paced beats, are predominant, the processor ignores other beat types and performs ischemia detection only on ventricularly paced beats. Conversely, if beats of a second beat type, such as sinus or atrially paced beats, are predominant, the processor ignores ventricularly paced beats and performs ischemia detection only on sinus or atrially paced beats. If there is a mixture of beat types such that neither predominates, the processor performs ischemia detection on both beat types.
    Type: Grant
    Filed: November 24, 2009
    Date of Patent: May 28, 2013
    Assignee: Angel Medical Systems, Inc.
    Inventors: David R. Fischell, Michael Sasha John, David Keenan
  • Publication number: 20130131528
    Abstract: A method of detecting and classifying cardiac arrhythmias, comprising: receiving a hemodynamic wave signal from at least one hemodynamic sensor by a processor; receiving a cardiac electrical wave signal from a cardiac stimulation device by the processor; integrating, by the processor, the received hemodynamic wave signal and the received cardiac electrical wave signal; determining if a heart arrhythmia is present via examination of the regularity of the hemodynamic signal; and if a heart arrhythmia is determined, classifying the arrhythmia according to a time correlation between the hemodynamic signal and the electrical signal.
    Type: Application
    Filed: May 23, 2012
    Publication date: May 23, 2013
    Inventor: Rami Rom
  • Publication number: 20130131529
    Abstract: Systems and methods are disclosed to determine one or more sensing zones on a body surface for electrocardiographic mapping of a region of interest associated with the heart. The sensing zone can be utilized to facilitate acquisition, processing and mapping of electrical activity for the corresponding region of interest. In other examples, an application-specific arrangement of electrodes can also be provided based on the sensing zone that is determined for the region of interest.
    Type: Application
    Filed: October 12, 2012
    Publication date: May 23, 2013
    Applicant: CARDIOINSIGHT TECHNOLOGIES, INC.
    Inventor: CARDIOINSIGHT TECHNOLOGIES, INC.
  • Publication number: 20130131527
    Abstract: A first cardiac signal associated with an activity of a first implant site of a heart during a cardiac cycle is sensed. A second cardiac signal is sensed using an intrapericardial lead located on an epicardial surface proximate a second implant site of the heart. The second cardiac signal is associated with an activity of the second implant site during the cardiac cycle. A timing delay between the activity of the first implant site and the activity of the second implant site is obtained and analyzed to determine if the intrapericardial lead location is appropriate. The preceding is repeated until an appropriate intrapericardial lead location is determined. Other measurements obtained during implant determine whether the intrapericardial lead location is at or near slow conduction zone and whether the intrapericardial lead is placed at the location having the greatest mechanical delay. Post implant measurements determine whether the intrapericardial lead has migrated.
    Type: Application
    Filed: November 21, 2011
    Publication date: May 23, 2013
    Applicant: PACESETTER, INC.
    Inventors: Xiaoyi Min, Anna Raskin, Kevin L. Morgan, Stephanie Toy, Joyce Tao
  • Patent number: 8442631
    Abstract: A method for monitoring a biological cardiac pacemaker. The method may include stimulating a heart at a region selected for implantation of a biological pacemaker and sensing at least one electrical signal indicative of a cardiac depolarization originating in the region selected for implantation of the biological pacemaker. The method may further include sensing at least one subsequent electrical signal produced by the heart and determining if the subsequent electrical signal originated in the region selected for the biological pacemaker or another region of the heart.
    Type: Grant
    Filed: May 8, 2007
    Date of Patent: May 14, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Bruce KenKnight, Steven D. Girouard
  • Patent number: 8433396
    Abstract: In general, the invention provides for commencing an atrioventricular (AV) search in response to an indicator of an autonomic nervous system (ANS) activity. An implantable medical device (IMD) may be configured to apply this technique, and also to apply rate adaptive ventricular pacing. In response to ANS activity such as an abrupt increase in cardiac sympathetic nervous activity, the IMD performs an AV search to find the intrinsic AV interval of the patient. The invention includes selection of a maximum AV delay so that the AV search will not adversely affect hemodynamic function.
    Type: Grant
    Filed: April 18, 2003
    Date of Patent: April 30, 2013
    Assignee: Medtronic, Inc.
    Inventor: Bozidar Ferek-Petric
  • Publication number: 20130102912
    Abstract: A method of predicting ventricular arrhythmias includes receiving an electrical signal from a subject's heart for a plurality of heart beats, identifying characteristic intervals and heart beat durations of the electrical signal corresponding to each of the plurality of heart beats to provide a plurality of characteristic intervals with corresponding heart beat durations, representing dynamics of the plurality of characteristic intervals as a function of a plurality of preceding characteristic intervals and durations of corresponding heart beats over a chosen period time, assessing a stability of the function over the chosen period of time, and predicting ventricular arrhythmias based on detected instabilities in the dynamics of the characteristic intervals.
    Type: Application
    Filed: December 16, 2010
    Publication date: April 25, 2013
    Applicant: THE JOHNS HOPKINS UNIVERSITY
    Inventors: Natalia A. Trayanova, Xiaozhong Chen
  • Patent number: 8428698
    Abstract: Implantable systems, and methods for use therewith, are provided for monitoring a patient's diastolic function and/or heart failure (HF) condition. A signal indicative of changes in arterial blood volume and a signal indicative of electrical activity of the patient's heart are obtained. Beginnings of diastolic periods can be detected based on a feature of the signal indicative of changes in arterial blood volume. Ends of the diastolic periods can be detected based on a feature of the signal indicative of electrical activity of the patient's heart, or on the signal indicative of changes in arterial blood volume. Diastolic periods (DPs), isovolumic relaxation times (IVRTs) and/or diastolic filling times (DiFTs) can be estimated based on the detected beginnings of the diastolic periods and detected ends of the diastolic periods. The patient's diastolic function and/or HF condition (and/or changes therein) can be monitored based on the estimates of DP, IVRT and/or DiFT.
    Type: Grant
    Filed: May 29, 2009
    Date of Patent: April 23, 2013
    Assignee: Pacesetter, Inc.
    Inventors: Allen J. Keel, Brian Jeffrey Wenzel, Edward Karst, Wenbo Hou, Taraneh Ghaffari Farazi
  • Publication number: 20130096446
    Abstract: A method of differentiating between supraventricular tachyarrhythmia (SVT) and ventricular tachyarrhythmia (VT) is disclosed. A post pacing interval (PPI) is determined based on a biomarker dataset. The post pacing interval is statistically analyzed relative to a threshold to differentiate between SVT and VT. A further method of differentiating between SVT and VT is disclosed. A PPI is determined based on a biomarker dataset. A tachycardia cycle length (TCL) is also determined based on the biomarker dataset. A difference of the PPI minus the TCL is statistically analyzed relative to a threshold to differentiate between SVT and VT. A non-transitory computer readable medium and a system are also disclosed for differentiating between SVT and VT.
    Type: Application
    Filed: October 5, 2012
    Publication date: April 18, 2013
    Applicants: KINGSTON GENERAL HOSPITAL, QUEEN'S UNIVERSITY AT KINGSTON
    Inventors: Queen's University at Kingston, Kington General Hospital
  • Publication number: 20130085403
    Abstract: The present disclosure is directed to an electrogram summary. In various examples, a subset of cardiac episodes are selected and displayed based on a set of summary rules. The subset of cardiac episodes includes at least one episode from each of a plurality of episode categories with at least one cardiac episode. In some examples, the order in which the cardiac episodes selected are displayed is based on the set of summary rules. The electrogram summary may include images or information regarding each of the selected cardiac episodes.
    Type: Application
    Filed: September 30, 2011
    Publication date: April 4, 2013
    Applicant: Medtronic, Inc.
    Inventors: Bruce D. Gunderson, Karen J. Kleckner, Kevin T. Ousdigian, Amisha S. Patel, Julian Sanchez
  • Patent number: 8412316
    Abstract: A system and method provide for detecting atrial arrhythmias within an implantable medical device capable of sensing and pacing at least an atrium of a heart. Arrhythmia of the atrium is detected. In response to detecting atrial arrhythmia, delivery of pacing signals to the atrium is inhibited under certain conditions. While delivery of the pacing signals to the atrium is inhibited, the detected arrhythmia of the atrium is confirmed during a period of further evaluation. Delivery of pacing signals to the atrium is enabled upon ceasing of the atrial arrhythmia. Inhibiting delivery of the pacing signals during atrial arrhythmia evaluation advantageously provides for an increase in the rate at which the detected arrhythmia is confirmed.
    Type: Grant
    Filed: August 16, 2011
    Date of Patent: April 2, 2013
    Assignee: Cardiac Pacemakers, Inc.
    Inventors: Gary Seim, David Perschbacher
  • Publication number: 20130079651
    Abstract: The present disclosure is directed to the classification of cardiac episodes using an algorithm. In various examples, an episode classification algorithm evaluates electrogram signal data collected by an implantable medical device. The episode classification algorithm may classify may include a sinus template and a comparison of the electrogram signal to the sinus template. Possible classifications of the cardiac episode may include, for example, unknown, inappropriate, appropriate, supraventricular tachycardia, ventricular tachycardia, ventricular fibrillation or ventricular over-sensing.
    Type: Application
    Filed: September 26, 2011
    Publication date: March 28, 2013
    Applicant: Medtronic, Inc.
    Inventors: Amisha S. Patel, Bruce D. Gunderson, Mark L. Brown