Abstract: The present application relates to a method for preparing a medical product, the method comprising providing an aqueous dispersion of nanofibrillar cellulose, providing a nonwoven fabric, immersing the nonwoven fabric in the aqueous dispersion of nanofibrillar cellulose to form a coating on the nonwoven fabric, passing the immersed nonwoven fabric through a prefined gap to define the thickness of the coating on the immersed nonwoven fabric without pressing, and dewatering the immersed nonwoven fabric, to obtain the medical product. The present application also relates to a medical product comprising a supporting layer and an absorbent layer, wherein the supporting layer comprises a nonwoven fabric, and the absorbent layer comprises unpressed nanofibrillar cellulose having an average fibril diameter of 200 nm or less, wherein the absorbent layer is coating the supporting layer.

Abstract: The present application provides a medical multi-layer product comprising a layer comprising nanofibrillar cellulose, and a layer of gauze. The present application also provides a medical product comprising the medical multi-layer product, and a cosmetic product comprising the medical multi-layer product. The present application also provides a method for preparing a medical multi-layer product, the method comprising providing a filter, providing a dispersion comprising nanofibrillar cellulose, providing a gauze, applying the dispersion onto the filter, applying the gauze onto the dispersion, and dewatering the structure through the filter to obtain the medical multi-layer product.

Abstract: The present invention relates to a hydrophilic foam material, which is of particular use in wound treatment, and to a method for producing said hydrophilic foam material. The hydrophilic foam material has nucleating particles, wherein at least 85% of all foam cells in said foam material have an average cell size of 0.01 mm2 or less.

Abstract: The present invention provides dry-creped absorbent material comprised of gelling fibres intended for use particularly, but not necessarily exclusively, as wound dressings or as a component (absorbent substrate) of a wound dressing, as well as wound dressings comprising the absorbent material.

Abstract: It can be difficult to remove atomically thin films, such as graphene, graphene-based material and other two-dimensional materials, from a growth substrate and then to transfer the thin films to a secondary substrate. Tearing and conformality issues can arise during the removal and transfer processes. Processes for forming a composite structure by manipulating a two-dimensional material, such as graphene or graphene-base material, can include: providing a two-dimensional material adhered to a growth substrate; depositing a supporting layer on the two-dimensional material while the two-dimensional material is adhered to the growth substrate; and releasing the two-dimensional material from the growth substrate, the two-dimensional material remaining in contact with the supporting layer following release of the two-dimensional material from the growth substrate.

Abstract: A see-through dressing assembly is presented for use with a reduced-pressure system for treating a wound on a patient using reduced pressure that allows visual observation of the wound during treatment. The dressing assembly includes a bolster for providing a directed force when under reduced pressure, a sealing member for covering the bolster and providing a seal over the bolster and a patient's epidermis, and wherein the bolster and sealing member are formed from see-through materials sufficient to allow perception of color from a point external to the system. Other systems, dressings, and methods are presented.

Abstract: Methods for promoting re-epithelialization and granulation as an aspect of wound healing are presented. A method for promoting granulation and re-epithelialization of a wound at the same time involves using a reduced-pressure treatment dressing and applying a moist, water-sensitive barrier to promote re-epithelialization and to inhibit granulation. Other methods are also presented.

Abstract: Methods, apparatuses, and systems for promoting re-epithelialization as an aspect of wound healing are presented. A re-epithelialization dressing for use with reduced pressure has a moist tissue-interface layer, a manifold member, and a sealing member. The moist tissue-interface layer has a plurality of apertures. The moist tissue-interface layer is for disposing adjacent to the wound and provides a moisture balance (i.e., provides moisture when the wound is dry and receives moisture when the wound site is substantially wet). The reduced pressure, apertures, and moist tissue-interface layer help with liquid management and otherwise promote re-epithelialization. Other systems, apparatuses, and methods are presented.

Abstract: An absorbent article, the absorbent article being a personal hygiene article, includes a liquid permeable top sheet, a liquid impermeable back sheet, an absorbent core enclosed between the top sheet and the back sheet, and a fluid flow control member arranged between the top sheet and the backsheet. The fluid flow control member is a spacer fabric including a top layer, a bottom layer and an interconnecting layer of pile filaments between the top layer and the bottom layer. The spacer fabric has a ratio of thickness to basis weight at 15 kPa of at least 1.5·10?5 m/gsm, as measured according to the Mecano-method disclosed herein.

Abstract: The present invention relates generally to systems and methods and systems for generating polymer foams within body cavities to locate and/or control bleeding. The present invention further relates to methods and systems for generating polymer foams within non-compressible wounds to control or stop bleeding. The present invention further relates to the use of foams and gels for medical and cosmetic purposes.

Abstract: A sponge-like polymeric adsorption material prepare by a process including: preparing a linear polymer yarn from a linear polymer via melt-blow spinning, treating the linear polymer yarn with a crosslinking agent and a porogen agent; heating the treated linear polymer yarn at 130 to 150° C. for 25 to 35 seconds to obtain a fibrous polymeric adsorption material; and weaving the fibrous polymeric adsorption material to obtain the sponge-like polymeric adsorption material. The linear polymer has a molecular weight of 15,000 to 20,000 g/mol. The fibrous polymeric adsorption material includes fibers with a diameter of 4 to 6 microns. The crosslinking agent is in an amount of 1 to 3 weight % of the linear polymer. The crosslinking agent is a diacrylate ester compound having Formula J1, J2 or J3. The porogen agent is in an amount of about 1 weight % of the linear polymer. The sponge-like polymeric adsorption material has a thickness of 15-20 mm and a density of 600-720 g/L.

Abstract: A method of preparing a fibrous polymeric adsorption material includes preparing a linear polymer yarn from a linear polymer via melt-blow spinning, the linear polymer having a molecular weight of 15,000 to 20,000 g/mol; treating the linear polymer yarn with a crosslinking agent and a porogen agent; and heating the treated linear polymer yarn at 130 to 150° C. for 25 to 35 seconds to obtain the fibrous polymeric adsorption material. The fibrous polymeric adsorption material includes fibers with a diameter of 4 to 6 microns. The crosslinking agent is in an amount of 1 to 3 weight % of the linear polymer. The crosslinking agent is a diacrylate ester compound having Formula J1, J2 or J3. The porogen agent is in an amount of about 1 weight % of the fibrous polymeric adsorption material.

Abstract: The present invention provides an absorbent wound dressing assembly that can be used to stanch, seal, or stabilize a site of tissue injury, tissue trauma, or tissue access. The wound dressing assembly is flexible so that it can be adapted and used to fit in narrow and small wound sites. Generally the wound dressing assembly comprises a flexible carrier material that is impregnated with a non-mammalian material for control of severe bleeding. The preferred non-mammalian material is poly [?-(1?4)-2-amino-2-deoxy-D-glucopyranose] more commonly referred to as chitosan.

Abstract: An elongate adhesive article having a length substantially greater than a width includes a backing layer having an adhesive layer and a single weakened region formed of a removable strip of backing layer that is oriented substantially perpendicular to the article length. The removable strip of backing layer is at least partially defined by a pair of lines of weakness separated by a gap of between about 2 and about 15 mm. The elongate article may include an absorbent pad in the form of an adhesive bandage or sticking plaster. A method of using such an elongate article includes the steps of applying the article to the skin of a mammal, removing a predefined strip from the article; and removing the remainder of the article from the skin.

Abstract: The invention refers to a disposable absorbent article such as a diaper, a pant or a sanitary napkin. The disposable absorbent article further comprises a structure which is able to elongate and simultaneously convert from an initial flat configuration into an erected configuration.

Abstract: A composite comprising a stem cell; a biodegradable layer, which can provide an environment for the stem cell to grow and to differentiate, and; a N-isopropylacrylamide (NIPAAm), which can polymerize with the biodegradable layer and possess the temperature-responsive character for easy stripping. The present invention further provides a method for treating a patient with a skin defect, consisting of (a) providing said patient with a composite consisting of a N-isopropylacrylamide (NIPAAm) layer polymerized with a biodegradable layer containing gelatin and a layer of polypropylene (PP) non-woven, wherein a bone marrow derived mononuclear cell with CD45 negative and glycophorin A negative is cultivating on the biodegradable layer; (b) covering said composite on the skin defect of the patient; and (c) treating the composite with water below 25° C. to strip off the layer of polypropylene (PP) non-woven.

Abstract: Wound dressing articles comprising a nonwoven web comprising a plurality of fibers having grafted pendant hydrophilic groups, methods that use high energy irradiation for making a plurality of fibers having grafted pendant hydrophilic groups, useful for making wound dressing articles.

Abstract: A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

Abstract: A medical device for example a wound dressing having antibacterial and optionally, antifungal properties, are provided together with methods for making the device. An exemplary dressing includes a layer of silver-containing fabric, (optionally) a layer of absorbent material, and (optionally) a layer of flexible air-permeable and/or water-impermeable material. The dressing can be used for prophylactic and therapeutic care and treatment of skin infections and surface wounds (including surgical incisions), as a packing material, and as a swab for surface cleaning.

Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

Abstract: A wound care product having buffer substances and a wound cover. The wound cover has a foam. The pH value of the buffer solution obtained when the buffer substances are dissolved in demineralized water at 37° C. is between 3 and 7.

Abstract: The present invention pertains to nonwoven webs, and multi-component fibers comprising polydiorganosiloxane polyamide as well as method of making microfibers and multi-component fibers comprising a polydiorganosiloxane polyamide copolymer.

Abstract: The present disclosure provides self-adherent, elastic composite articles including a nonwoven fibrous coverweb, a woven scrim, and a plurality of spaced elastic yarns located between the coverweb and the woven scrim; these components are bonded together in a unified structure with a polymeric binder. The elastic composite articles generally demonstrate desirable hand-tear characteristics in the cross-web direction.

Abstract: A two layer bandage includes a padding layer; and an elastic layer, wherein the padding layer which includes a nonwoven material, and wherein fixing of filaments in the nonwoven material is implemented solely via needling and the padding layer is fixed to the elastic layer solely by needling.

Abstract: A device for protecting an area of skin of a human body includes a plate. The plate includes a first face covered by an external layer and a second face opposite the external layer. The second face is configured to be applied onto an area of skin to be protected. The plate also includes a protective part made of a polymer gel and at least one adhesive part made of a polymer gel. The protective part is configured to ensure mechanical protection of the area to be protected and the adhesive part is configured to come into contact with the skin. The adhesive part has an adhesive power greater than an adhesive power of the protective layer to hold the plate on the area to be protected.

Abstract: A therapeutic device for promoting the healing of a wound in a mammal is disclosed. An exemplary device comprises a permeable structure having a plurality of depressions formed in a surface thereof. In use, the surface having the depressions is disposed adjacent a surface of the wound. A method of manufacturing a therapeutic device for promoting the healing of a wound in a mammal comprising the steps of providing a permeable substrate, and forming a plurality of depressions into a surface of the permeable substrate to provide the therapeutic device. A method of treating a wound comprises: providing a permeable structure comprising a plurality of randomly disposed fibers and having i) a plurality of wound surface contact elements disposed between end portions of the structure, and ii) a plurality of voids defined by the contact elements; and applying the permeable structure to at least one surface of the wound.

Abstract: One subject of the present invention is a dressing essentially consisting of: an absorbent nonwoven compress formed from a mixture: of bicomponent thermal bonding non-absorbent fibers, of core-shell type, said core being made of polyester (polyethylene terephthalate, PET) and the shell being made of polyethylene; of bicomponent superabsorbent fibers of core-shell type with a core made of polyacrylonitrile and a shell made of polyacrylate; and a net fabric made from a hydrocolloid elastomer mass partially covering the face of the compress intended to come into contact with the wound. This product is especially intended to promote the healing of chronic wounds by optimizing the debridement.

Abstract: A method (400) of manufacturing a wound dressing is disclosed that includes obtaining alginate fibers (108) and the step (404) of spraying either the alginate fibers (108) or a dressing or dressing layer (610) of the alginate fibers with an aqueous solution (801) comprising a polysaccharide, which can be carboxymethylcellulose. The step of spraying can occur while the alginate fibers, dressing, or dressing layer are wet. A step (405) of flash drying can follow to remove the solute of the aqueous solution to leave the polysaccharide along the alginate. The step of spraying can be selective, such that only portions of the dressing layer include the polysaccharide.

Abstract: An apparatus for promoting the clotting of blood and controlling bleeding comprises a receptacle for retaining blood clotting material in particulate form therein. A pad for controlling bleeding comprises a mesh structure and a support attached to the mesh structure to facilitate the application of pressure to the pad and the wound. A bandage applicable to a bleeding wound comprises a mesh structure and a flexible substrate attached to the mesh structure, the substrate being a cloth or plastic member that may be adhesively attachable to cover a wound. In any embodiment, at least a portion of the receptacle or mesh structure is defined by a mesh having openings therein, and at least a portion of the particulate blood clotting material is in direct contact with blood. The mesh may include a zeolite powder impregnated or otherwise incorporated therein.

Abstract: A bandage for applying to a human or animal body, includes a two-dimensional tape material as base structure with a longitudinal extent, made of a textile material with a first side and a second side, wherein a cushion layer is provided on one of the two sides, at least over part of the longitudinal extent of the base structure, wherein the cushion layer is composed of threads and/or fibers which are part of the textile base structure, i.e. which are introduced into and/or drawn out of the textile base structure.

Abstract: The present invention relates to a wound dressing including a first wound pad and a first cover layer covering the first wound pad and extending beyond the first wound pad around the circumference thereof. According to the invention a second wound pad is disposed outside the first cover layer and enclosed in a second cover layer. Furthermore, the first and second wound pads are connected to each other by liquid transferring means.

Abstract: An apparatus for promoting the clotting of blood and controlling bleeding comprises a receptacle for retaining molecular sieve material in particulate form therein. A pad for controlling bleeding comprises a mesh structure and a rigid or semi-rigid support attached to the mesh structure to facilitate the application of pressure to the pad and the wound. A bandage applicable to a bleeding wound comprises a mesh structure and a flexible substrate attached to the mesh structure, the substrate being a cloth or plastic member that may be adhesively attached to cover a wound. In any embodiment, at least a portion of the receptacle or mesh structure is defined by a mesh having openings therein, and at least a portion of the particulate molecular sieve material is in direct contact with blood.

Abstract: A method for creating a non-adhesive, water-absorbent wound dressing includes creating a mixture of monomers, crosslinker, initiator, and solvent, initiating polymerization of the monomers to begin polymerization of the monomers; quenching the polymerization of the monomers when the mixture has a viscosity suitable for electrospinning; electrospinning the polymer mixture to form a fibrous membrane; and thereafter further polymerizing and crosslinking the fibrous membrane. The monomers are chosen from select species and, following this process, provide wound dressings that are nonadherent to a wound so as to be potentially reusable; superabsorbent; non-biofouling. With the addition of antimicrobial cations, the wound dressings also provide antimicrobial properties.

Abstract: A sheet preparation characterized by that fibrinogen is held on one surface of a sheet-shaped support and thrombin is held on the other surface of the sheet-shaped support where fibrinogen is not held and that fibrinogen and thrombin are held separately from each other, and a process for preparing the same.

Abstract: A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

Abstract: Systems and apparatuses for administering reduced pressure treatment to a tissue site including a wound filler for positioning adjacent a wound site on a patient. The wound filler includes at least one strand having a plurality of nodes positioned along a length of the strand. The at least one strand has a charged state and an uncharged state. In the charged state, the at least one strand includes a stored energy that when released would deform or move the at least one strand. In the discharged state, the stored energy has been released. The wound filler further includes a removable sheath encasing the at least one strand. The at least one strand transitions from the charged state to the uncharged state as the removable sheath is removed.

Abstract: A wound dressing product comprising: a substrate layer having an upper surface and a lower surface; a tacky silicone coating composition present on said upper surface and on said lower surface; and upper and lower release sheets covering said substrate and said tacky silicone coating composition on said upper and lower surfaces, respectively, and adhered to said surfaces by said tacky silicone coating composition, wherein said upper surface is less tacky than said lower surface whereby said upper release sheet can be removed from said upper surface more readily than said lower release sheet can be removed from said lower surface. The same silicone composition is used to form both the upper and the lower surface. Also provided are methods for making such dressings.

Abstract: A composite comprising a stem cell; a biodegradable layer, which can provide an environment for the stem cell to grow and to differentiate, and; a N-isopropylacrylamide (NIPAAm), which can polymerize with the biodegradable layer and possess the temperature-responsive character for easy stripping. The present invention further provides a method for treating a patient with a skin defect, consisting of (a) providing said patient with a composite consisting of a N-isopropylacrylamide (NIPAAm) layer polymerized with a biodegradable layer containing gelatin and a layer of polypropylene (PP) non-woven, wherein a bone marrow derived mononuclear cell with CD45 negative and glycophorin A negative is cultivating on the biodegradable layer; (b) covering said composite on the skin defect of the patient; and (c) treating the composite with water below 25° C. to strip off the layer of polypropylene (PP) non-woven.

Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

Abstract: A process for producing a wound dressing was provided having steps of: spinning an aqueous stock containing natural polymeric materials into a spin formation solution to form a wet polymeric spin; immersing the wet polymeric fiber into a softening reagent to obtain a softened wet polymeric spin; immersing the softened wet polymeric spin into a volatile reagent to expelling moisture in the softened wet polymeric fiber to form a polymeric fiber; forming a non-woven fabric of the polymeric fiber; and treating the non-woven fabric of the polymeric fiber with a coating solution to form a porous coating on the polymeric fiber to obtain a wound dressing. A process for manufacturing a polymeric fiber is also provided. A wound dressing produced by the process is also provided.

Abstract: The present invention is directed to a hemostatic textile, comprising: a material comprising a combination of glass fibers and one or more secondary fibers selected from the group consisting of silk fibers; ceramic fibers; raw or regenerated bamboo fibers; cotton fibers; rayon fibers; linen fibers; ramie fibers; jute fibers; sisal fibers; flax fibers; soybean fibers; corn fibers; hemp fibers; lyocel fibers; wool; lactide and/or glycolide polymers; lactide/glycolide copolymers; silicate fibers; polyamide fibers; feldspar fibers; zeolite fibers, zeolite-containing fibers, acetate fibers; and combinations thereof; the hemostatic textile capable of activating hemostatic systems in the body when applied to a wound. Additional cofactors such as thrombin and hemostatic agents such as RL platelets, RL blood cells; fibrin, fibrinogen, and combinations thereof may also be incorporated into the textile. The invention is also directed to methods of producing the textile, and methods of using the textile to stop bleeding.

Abstract: A dressing, comprising an inner layer and an outer layer; wherein the inner layer and the outer layer are aligned with trimming at one side of edge. The inner layer comprises hydrogel and meltblown nonwoven, and the outer layer comprises polyurethane film and pressure sensitive adhesive film. The dressing increases watertight closure. It could be applied in circular wound covering.

Abstract: A wound care product is a nonwoven fabric made of filaments bulked from a tow and fixed into a 3-dimensional structure.

Abstract: A hydrogel structure comprising: (a) a one way penetrating polyurethane film layer; (b) a hydrophobic pressure sensitive adhesive layer; (c) a multi-directional elastic meltblown nonwoven; (d) an interpenetrating polymer network; and (e) a hydrogel; wherein the meltblown nonwoven and the hydrogel are laminated by UV curing to form the interpenetrating polymer network, part of fibers of the meltblown nonwoven are exposed and fit stably with the pressure sensitive adhesive film. The hydrogel structure can make dressings multi-directional elastic for multiple traumas. The hydrogel structure can provide an environment suitable for wound healing, shorten the healing time, antiseptic and reduce the chances of being infected for the wound dressing.

Abstract: A non-adherent wound dressing (1) comprises a substrate (2) in the form of a perforated sheet of melt-blown non-woven material. The substrate (2) is impregnated with, and coated on both sides with, a silicone gel (3).

Abstract: The present invention is directed to a reinforced absorbable hemostat comprising at least one hemostatic agent in a single layer of nonwoven synthetic fabric having a mixture of compressed fiber staples of a polyglycolide/polylactide copolymer and a polydioxanone.

Abstract: A device for promoting the clotting of blood comprises a clay material in particle form and a receptacle for containing the clay material. At least a portion of the receptacle is defined by a mesh. Another device comprises a gauze substrate and a clay material disposed on the gauze substrate. Another device is a bandage comprising a substrate, a mesh mounted on the substrate, and particles of a clay material retained in the mesh. A hemostatic sponge comprises a substrate, a hemostatic material disposed on a first surface of the substrate, and a release agent disposed on a second surface of the substrate. The release agent is disposed on the wound-contacting surface of the substrate. When treating a bleeding wound, application of the hemostatic sponge causes at least a portion of the hemostatic material to come into contact with blood through the release agent and through the substrate.

Abstract: A hemostatic device for promoting the dotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

Abstract: The present invention is directed to a synthetic fabric comprising a multi-layered nonwoven fabric made from staples of a polyglycolide/polylactide copolymer, each layer having a different density. The multi-layer fabric can be used as a reinforced absorbable hemostat medical device.

Abstract: An emergency head trauma bandage cap with a detachable strap system and method of use, which, when applied to the head, delivers minimal pressure to control bleeding, doesn't compromise cervical spine immobilization, allows for fast and effective application of cold packs to control intracranial/internal swelling or hot packs to prevent hypothermia in non-trauma situations, doesn't come apart during treatment and transport, and doesn't require a caregiver to re-wrap the dressing.