Abstract: Medicinal pressure-sensitive adhesives, adhering to both dry and wet skin, characterized by a mixture of a) 20-50 wt-% of a hydrophilic (meth)acrylate copolymerizate containing tertiary amino groups, b) 20-50 wt-% of a hydrophobic (meth)acrylate copolymerizate containing carboxyl groups, c) 10-40 wt-% of one or more mono- or dicarboxylic acids, d) 0-10 wt-% of a polyol, and e) 0.02-0.5 wt-% of a cross-linking system reacting with at least one copolymerizate, whereby the sum of components a to e equals 100 wt-%, with a water-vapor permeability of ≧30,000 g·m−2·24 h−1, measured on a pressure-sensitive adhesive film with a thickness of 40 &mgr;m.

Abstract: There is provided a novel wound dressing material which has biocompatibility and infection controllability as essential properties required for such a material, especially excellent flexibility and water absorption properties, thereby accelerating smooth regeneration of a skin defect without stripping off the regenerating skin while removing the material from the skin. A healing agent is added to the wound dressing material which comprises an amorphous film of a crystallinity below 10% and contains fibroin and sericin as a main component.

Abstract: The wound filling device and method utilizes an alginate gel that is used to fill the wound. The alginate gel is then overlain with a dressing containing alkaline salts. The alkaline salts leach out of the dressing and into the gel. After penetrating the gel, the alkaline salts initiate hardening of the gel and binding of the gel to the dressing. Therefore, this gel can be easily removed along with the dressing without the need of potentially painful and damaging rinses.

Abstract: A low trauma pressure-sensitive adhesive coated substrate comprising a sheet material, tape or laminate structure designed to adhere to skin or like surfaces. The pressure-sensitive adhesive layer of this adhesive coated substrate is a fibrous adhesive layer generally having a basis weight of from 5 to 200 g/m2 applied to a conformable backing or substrate. The fibrous adhesive layer has a textured outer face and persistent porosity between discrete adhesive fibers. Generally, the fibrous adhesive layer has a MVTR (measured by ASTM E 96-80 at 40° C.) of at least 1000 g/m2/day, preferably at least 6000 g/m2/day.

Abstract: A fluid absorbent tape is formed from a fluid permeable strip which is folded to form overlapping portions enclosing an area filled with a band of a fluid absorbent particulate material lying on at least a part of a width of the upper surface of the strip. In one example, the strip is folded along one longitudinally extending fold line centrally between the side edges of the strip such that the side edges overlie on another and are bonded together by a bead of hot melt adhesive, a strip of EAA or other suitable method. In another arrangement, the side edges are folded together to form a butt joint which is bonded by an overlying or underlying strip of EAA or similar material. A second band of material can be provided in a second folded portion overlying the first to form an S-shape with both being maintained encapsulated by the bonding of the side edges of the strip.

Abstract: A therapeutic mat for application to a person includes a relatively elastic substrate of a predetermined size, a hydrogel substance connected to the elastic substrate, and a plurality of microcrystals dispersed throughout the hydrogel substance. The therapeutic mat may further include retaining straps connectable to the elastic substrate and of a size and configuration to extend about the part of the body for supporting the therapeutic mat in a relatively fixed position.

Abstract: Support material for medical purposes, which is characterized in that an addition of high-strength fibers or threads on an organic or inorganic base with a maximum tensile strength over 60 cN/tex gives the support material a maximum tensile strength of over 2 N/cm and the support material has mainly a maximum tensile strength of under 400%.

Abstract: A process for producing sterile nonwovens comprises a textile fabric composed of a fiber web being impregnated with an aqueous dispersion comprising a polyurethane, then dried and irradiated with .gamma.-rays.

Abstract: The present invention relates to a wound dressing 10 that is a porous, self-adhering elastic 14 bandage which may be compressively wrapped around a wound and which is capable of absorbing fluids and wound exudate. A preferred embodiment of the wound dressing 10 is a self-adhering elastic substrate 14 which does not adhere to clothing, hair or skin having a compressive force when extended that provides a therapeutic benefit and which is flexibly attached or fixed to an absorbent layer 12.

Abstract: A hospital type of bandage integrates an absorbent pad and non-stick layer with a fluid-impermeable outer layer and an adhesive in a single composite structure. In a preferred embodiment the invention further includes means which may be used to turn the bandage inside out upon removal, so that surfaces once contacting a patient are no longer externally exposed. A bandage according to the invertible embodiment preferably includes a pocket formed on the side of the bandage facing away from the patient after application, this pocket being large enough to accommodate at least a portion of a human hand, and inside this pocket and located opposite the entrance is a means for grasping which may be pulled outwardly through pocket opening, thereby inverting the entire structure. Various forms of devices for grasping are possible as alternatives, including a string, a tab and a tab with one or more finger-receiving holes.

Abstract: A device for use in promoting wound healing is made of a substrate formed of a biologically acceptable material and has there on means capable of orienting cell growth so as to allow guided tissue repair. The means for orienting cell growth may include grooves embossed or stamped on a surface of the substrate.

Abstract: Biomaterials are disclosed comprised of biodegradable, biocompatible, and bioabsorbable non-woven fabric materials for use in surgery for the guided regeneration of tissues. The non-woven fabric materials constitute threads embedded in a matrix, wherein both the matrix and the threads constitute auto-crosslinked hyaluronic acid.

Abstract: The invention is a wound dressing prepared from alginate fibers which have good structural integrity, whereby layers are firmly joined together, e.g. by stitching or calendering at a plurality of points to produce a composite fabric.

Abstract: A polyvalent cation crosslinked pectin fiber composition is composed of a calcium sensitive low methoxyl pectin with a degree of esterification (DE) of less than 15% or calcium sensitive amidated pectin having a DE of less than 50% where the pectin is polyvalent cation crosslinkable and has an average molecular weight (MW) having an upper limit of 200,000 and a lower limit of 5000. This pectin is useful in making wound dressings for topical applications.

Abstract: Provided is a multilayered of nonwoven material comprising a surface layer which comes into contact with the skin, and one or more other layers which do not come into contact with the skin, wherein said surface layer which comes into contact with the skin is a member selected from the group consisting of a surface layer comprising at least one hyaluronic acid ester, a surface layer comprising a mixture of said at least one hyaluronic acid ester and at least one natural polymer, semisynthetic polymer, or synthetic polymer, and a surface layer comprising a natural, synthetic, or semisynthetic biocompatible perforated membrane compatible with cell growth on its surface. This material can be employed in a wide variety of medical and sanitary applications, including surgery and as a non-adhesive covering material.

Abstract: A hospital type of bandage integrates an absorbent pad and non-stick layer with a fluid-impermeable outer layer and an adhesive in a single composite structure. In a preferred embodiment the invention further includes means which may be used to turn the bandage inside out upon removal, so that surfaces once contacting a patient are no longer externally exposed. A bandage according to the invertible embodiment preferably includes a pocket formed on the side of the bandage facing away from the patient after application, this pocket being large enough to accommodate at least a portion of a human hand, and inside this pocket and located opposite the entrance is a means for grasping which may be pulled outwardly through pocket opening, thereby inverting the entire structure. Various forms of devices for grasping are possible as alternatives, including a string, a tab and a tab with one or more finger-receiving holes.

Abstract: The invention concerns a process for obtaining a skin substitute and the skin substitute itself. According to this process, a dermis substitute is prepared by mixing contractile cells, a nutritive medium, and collagen, in order to form a contracting gel; this dermis substitute is used as a substrate for an epidermis substitute obtained by culturing, using keratinocytes from an animal or human skin sample. According to the invention, the substrate is implanted with at least one section of a hair follicle retaining at least partially its cellular sheath, this section being implanted perpendicularly to the free surface of the substrate.

Abstract: Biomaterials are disclosed comprised of biodegradable, biocompatible, and bioabsorbable composite membranes for use in surgery for the guided regeneration of tissues. The composite membranes are comprised of threads embedded in a matrix, wherein both the matrix and the threads can be comprised of esters of hyaluronic acid, used singly or in combination, or esters of hyaluronic acid in combination with esters of alginic acid or other polymers.

Abstract: This invention relates to an adhesive sheet material, such as an adhesive tape, which is suitable for use on wet surfaces, in particular upon wet skin. The adhesive sheet material effectively binds to the wet surface and moves moisture away from the surface. The adhesive sheet material has a porous backing having opposing sides and is made of non-wettable fibers. The water-insoluble pressure sensitive adhesive is discontinuously coated on one side of the backing to provide areas of the adhesive interspersed with areas of bare backing.

Abstract: Adhesive bandages having a peripherally-raised non-adhesive thin-layer bordering the adhesive surface of such bandages is disclosed. The non-adhesive thin-layer inhibits formation of dirt rings which would otherwise remain when the adhesive bandage is removed from human skin.

Abstract: Biomaterials are disclosed comprised of biodegradable, biocompatible, and bioabsorbable nonwoven fabric materials for use in surgery for the guided regeneration of tissues. The non-woven fabric materials are comprised of threads embedded in a matrix, wherein both the matrix and the threads can be comprised of esters of hyaluronic acid, used singly or in combination, or esters of hyaluronic acid in combination with esters of alginic acid or other polymers.

Abstract: The invention provides high elongation thermally bonded nonwoven fabrics which exhibit elongation of at least about 130% in the cross-machine direction. The fabrics of the invention include a nonwoven a web of polyolefin staple fibers having an elongation of at least 400 percent, and a multiplicity of discrete thermal bonds throughout the web to provide a bond area of from 8 to 25 percent of the area of the fabric.

Abstract: A moisture vapor permeable, water impervious padding including sheets or strips of a lofted non-woven fabric having wax, silicone resin or fluorinated polymer at a surface layer thereof. The sheet or strip may be formed into a tube and contain an elastic component in the circumference to result in an elastically extensible tubular undercast padding.

Abstract: A wound dressing of alginate staple fibers has improved integrity when its fibers have been hydroentangled. Even when its basis weight is as low as 50 g/m.sup.2, the resulting wound dressing, when saturated with saline fluids, can be removed by forceps from a wound as a single piece, having little or no residue in the wound. At basis weights below 50 g/m.sup.2, the wound dressing preferably includes reinforcing fibers such as rayon.

Abstract: A compress for dressing wounds contains a depot layer (1) for storing liquids. A guiding layer (2) is assigned to the side of the depot layer (1) which faces the front side of the compress, which guiding layer is constructed in such a manner that the secretion which reaches it can spread out predominantly along said layer (2), before it reaches the depot layer (1). In order to achieve this effect, channels (3) are formed in the surface of the guiding layer (2) which faces the front side of the compress. Said channels (3) extend in the direction of the surface of the guiding layer (2). The two layers (1, 2) are arranged between a surface ply (10) and a lower sealing layer (15), the edges (16, 17) of which are bonded. Liquids which reach the surface layer spread out rapidly and evenly over the entire surface of the compress.