Abstract: In order to make available a wound dressing (100) with at least one energy transfer agent (11, 12) and a wound dressing (13), namely a combination of wound dressing and electrode for the stimulation treatment, with which an uniform electrostimulation of the wound can be achieved so that the wound healing process is considerably improved, it is proposed that the energy transfer agent has at least two layers and that the energy transfer agent (11, 12) has at least two adjacent layers (11, 12), a first layer (11)—energy supply—and a second energy—distribution of energy—(12), whereby the first layer (11) has a lower electric resistance and the second layer (12) a higher electric resistance.

Abstract: A pad of elastomeric material having a softness of no more than about durometer 50 Shore 00. The pad may carry adhesive and/or a housing for adhering the pad to a surface, either directly or indirectly through an envelope which surrounds the pad and carries the adhesive. Such a pad exhibits hemostatic and leak prevention properties against needle puncture holes in the skin or the wall of a hollow medical device. Particularly, hemostasis may be prevented with low pressure application of the pad to the skin. The pad may be previously applied to the skin of the patient or a wall of a medical device such as tubing or a solution bag, and the needle may then penetrate both the pad and the skin or medical device wall, to make a resealable puncture with leakage reduction and hemostasis when the needle is withdrawn.

Abstract: A disposable bandage for covering a wound area of a skin surface includes a self adhesive first fastener portion and a second fastener portion, a dome having a generally rectilinear shape and constructed from a thin rigid material, the dome being coupled to the first fastener portion along one edge and coupled to the second fastener portion along a second edge. The dome includes pleats that extend across the dome shape from the top edge to the bottom edge of the dome. A gasket is formed of a stretchable material and extends around the underside of the dome. The gasket is held in contact with the skin surface when the first fastener portion and the second fastener portion are pressed to a user's skin and, when the first fastener portion and the second fastener portion are moved away from each other, the pleats are unfolded and the gasket material is stretched and remains in contact with the skin surface.

Abstract: An antibacterial bandage formed from at least one foam with at least one antimicrobial agent and at least one hemostatic agent is disclosed. The at least one antimicrobial agent and the at least one hemostatic agent may be mixed with materials forming the foam during manufacture of the at least one foam.

Abstract: The present invention provides a multilayer bandage, comprising a webbing for contacting a wound and a first membrane that comprises at least one water-insoluble polymer and is water-impervious. The present invention further provides methods for making the multilayer bandage, methods of using the multilayer bandage for accelerated wound healing, and kits comprising compositions of the present invention.

Abstract: An integrated wound dressing system and method including a bandage and a self-contained receptacle that stores treatment material for the care and treatment of wounds. The treatment material is easily accessible and can be removed from the receptacle through an exit. The treatment material can then be used to control bleeding and/or clean the wound before dressing. The bandage may include a layer of plastic that acts as an occlusion barrier to reduce heat loss and maintain moisture levels at the wound site. The occlusion barrier also acts to prevent the passage of air into or out of the wound site. The bandage also includes fasteners that act to prevent unintentional unraveling and to secure the bandage during final packaging. These fasteners help facilitate the wrapping of amputations, stumps, and extremities. The integrated wound dressing system provides an all-in-one system for treating and dressing wounds and reduces the time required to do so.

Abstract: A dressing having a flexible sleeve shaped to accommodate a substantially cylindrical body or plant portion, the sleeve having a lining which is substantially non-adherent to the body or plant part being bandaged and having a peripheral securement means which attaches two peripheral portions to each other without those portions being circumferentially adhered to the sleeve portion.

Abstract: A composite dressing including a first polymeric layer, a second polymeric layer, a metal oxide, and a pharmaceutical active material is provided. The second polymeric layer is biocompatible and is disposed on a surface of the first polymeric layer. The metal oxide is distributed inside or on at least one surface of the first polymeric layer, while the pharmaceutical active material is distributed inside or on at least one surface of the second polymeric layer.

Abstract: The invention is directed to a spray-on, multilayer, non-woven fabric system and multilayer topical coverings suitable for reducing or alleviating a discomforting condition of the skin and/or an area underlying the skin when applied thereto, where the fabric system includes a first spray-on composition containing a material suitable for reducing or alleviating a discomforting condition of the skin and/or an area underlying the skin when applied thereto, and a second spray-on composition, different from the first spray-on composition for covering the first composition, which includes fibers, a volatile carrier, and a binding agent, and where the multilayer topical covering includes a first layer formed from the first spray-on composition and a second layer covering the first layer, the second layer formed from the second spray-on composition.

Abstract: A custom fabricated (e.g. custom shaped and dimensioned) wound dressing that matches a corresponding, pre-mapped integumentary wound includes one or more liquid flow barriers composed for example of a hydrophobic and high viscosity liquid embedded in a layer of the dressing. One such embedded hydrophobic liquid barrier covers a skin section immediately adjacent to the wound opening so as to protect the skin section from harmful liquids such as exudates or water. In one embodiment, the skin protecting barrier is substantially comprised of a silicone oil having a viscosity in the range of about 100 cSt to 1000 cSt.

Abstract: A nanofiber-reinforced composition suited to applying to a wound site in a human body includes a carrier liquid and nanofibers dispersed therein. The viscosity of the composition is such that it is able to be applied through a tube yet adhere proximate the wound site to provide a barrier layer which assists in healing of the wound by spacing it from neighboring organs.

Abstract: Described herein are coatings containing water-soluble oligodynamic metal salts that are formulated and applied from hydrophobic solvents. In particular, articles of manufacture comprising polymer coatings containing oligodynamic metal salts can include hydrophobic polymer coatings made from water-reactive monomers and hydrophilic polymers compounded in hydrophobic solvents which contain a small amount of water that aids in the solubilization and suspension of the oligodynamic metal salts. Methods of preparing these antimicrobial polymer coatings, and methods of coating a substrate to produce an article of manufacture having an antimicrobial polymer coating are also described.

Abstract: A dressing having a flexible sleeve shaped to accommodate a substantially cylindrical body or plant portion, the sleeve having a lining which is substantially non-adherent to the body or plant part being bandaged and having a peripheral securement means which attaches two peripheral portions to each other without those portions being circumferentially adhered to the sleeve portion.

Abstract: The hemostatic bandage kit and associated method of use operates to yield a rapidly deployable hemostatic wound treatment to enable medical personnel to more quickly respond to traumatic injuries involving massive blood loss, thereby saving lives. The hemostatic bandage kit does not require a medical facility, or alternatively, medical personnel or others in the field, to separately store or carry the components necessary to create a hemostatic wound treatment. All of the components are cooperatively stored in an integrated kit that is easily transported, stored, and deployed. The components include an inner membrane retaining a solvent therein, and an outer membrane retaining an absorptive material and a clotting agent, wherein the inner membrane is adapted to rupture and mix the solvent with the clotting agent and to saturate the absorptive material for application to a wound.

Abstract: An underpad including a top fabric layer constructed of a therapeutic fabric for the prevention and treatment of skin wounds, and pressure wounds in particular, is disclosed. The underpad also includes an absorbent middle layer and liquid impermeable bottom layer. The therapeutic fabric includes warp yarns and filling yarns woven to provide a smooth fabric surface. One of the warp or filling yarns is at least about 40% by weight of the therapeutic fabric of continuous filament nylon, and the other of the warp or filling yarns is from about 0% to about 60% by weight of the therapeutic fabric of continuous filament polyester or nylon having non-round filament cross sections. The therapeutic fabric includes a conductive yarn at about 1% to about 2% by weight to control static dissipation, and an antimicrobial substance is topically applied or inherently available in the therapeutic fabric. A method of preventing and treating skin wounds, and pressure wounds in particular, is also disclosed.

Abstract: In general, the basic material forming the wound dressing, covering, and/or application system of the present invention for use in blood coagulation comprises a combination of one or more components selected from the group consisting of clay materials, a molecular sieve material, principally zeolite, and inorganic oxide materials. Although the actual process which enables the wound dressing, covering, and/or application system of the present invention to effectively coagulate flowing blood is unknown, it is believed that the molecular sieve material selectively absorbs small molecules, such as water, from the blood. Due to the absorption of the water molecules, it is believed that the rate of blood clotting is increased.

Abstract: The present disclosure is directed to a breast skin care dressing. The breast skin care dressing comprises a moisture barrier layer having an inner surface and a perimeter. An absorbent liner covers at least a portion of the inner surface of the moisture barrier layer. The absorbent liner and the moisture barrier form a three-dimensional cup portion generally shaped for receiving a breast. An adhesive is positioned proximate the perimeter so as to be capable of maintaining a position of the absorbent liner adjacent to the breast.

Abstract: A wound dressing composition comprising a partially cured polyurethane fluid. The composition can be injected directly into a wound, where it cures to form a wound filling dressing. Also provided is a wound dressing comprising such a composition. Also provided is a kit for the preparation of such wound dressings, the kit comprising (a) a polyurethane prepolymer; and (b) a curing agent for the polyurethane prepolymer. Preferably, the polyurethane components comprise reaction products of a diisocyanate with castor oil or a related ester of ricinoleic acid or its derivatives.

Abstract: A wound treatment device for treating damaged body tissue comprising an encapsulating member having a size and shape capable of being attached to a patient to encapsulate a wound. A fluid communication member is provided for introducing treatment fluid within the encapsulating means for treatment of the wound. The fluid communication member is connected with a supply means for supplying treatment fluid thereto. The fluid communication member is capable of simultaneously transmitting multiple treatment fluids from the supply means into said encapsulating member. The inner surface of the wall of the encapsulating member is textured to allow fluid flow across the wound. The encapsulating member is also formed from a clear material to permit continuous visual inspection of the wound while maintaining a sterile environment.

Abstract: The present invention provides a transdermal drug administration device capable of freely controlling release of the drug. The transdermal drug administration device of the present invention contains a backing layer and a matrix layer provided on at least one surface of the backing layer, wherein the matrix layer contains a region located on a proximal side from the backing layer and a region located on a distal side from the backing layer, and the water-absorbing polymers therein have different weight concentrations, which enables high control of a drug released from the device.

Abstract: A disposable bandage for covering a wound area of a skin surface includes a self adhesive first fastener portion and a second fastener portion, a dome having a generally rectilinear shape and constructed from a thin rigid material, the dome being coupled to the first fastener portion along one edge and coupled to the second fastener portion along a second edge. The dome includes pleats that extend across the dome shape from the top edge to the bottom edge of the dome. A gasket is formed of a stretchable material and extends around the underside of the dome. The gasket is held in contact with the skin surface when the first fastener portion and the second fastener portion are pressed to a user's skin and, when the first fastener portion and the second fastener portion are moved away from each other, the pleats are unfolded and the gasket material is stretched and remains in contact with the skin surface.

Abstract: The invention relates to a dressing for a wound, containing a first layer which is formed by an absorbent matrix and an antimicrobially active substance. The substance is provided on a surface of the matrix in a chemically or physically bonded matter. The surface of the matrix with the substance is coated with a hydrophilic polymer.

Abstract: A hemostatic device for promoting the clotting of blood includes a gauze substrate, a clay material disposed on the gauze substrate, and also a polyol such as glycerol or the like disposed on the gauze substrate to bind the clay material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood emanating from the wound to cause the clotting. A bandage that can be applied to a bleeding wound to promote the clotting of blood includes a flexible substrate and a gauze substrate mounted thereon. The gauze substrate includes a clay material and a polyol. A hemostatic sponge also includes a gauze substrate and a dispersion of hemostatic material and a polyol on a first surface of the substrate.

Abstract: The present invention is directed to a method for imparting antimicrobial characteristics to hydrophilic fabrics. The method involves: (1) providing a hydrophilic fabric; (2) providing a first solution comprising at least one oligodynamic metal ion, wherein the first solution is free of basic nitrogen compounds; (3) contacting the hydrophilic fabric with the first solution to allow the hydrophilic fabric to absorb metal ions from the first solution; and (4) precipitating or reducing the metal ions that have been absorbed by the fabric so that the hydrophilic fabric contains an oligodynamic metal salt or free oligodynamic metal and has antimicrobial characteristics. The invention is also directed to disposable medical cloths having antimicrobial characteristics.

Abstract: The present invention provides a fiber with iodinated resin particles embedded therein. The innovative fibers a show no or negligible leaching of iodine into the atmosphere and thus are not toxic. In one aspect, the antimicrobial fibers can be bonded or woven together to form a filter media. Examples of nonwoven filters are provided. Additionally, an electric charge can be applied across the nonwoven substrate to increase antimicrobial efficacy.

Abstract: The present invention relates to a patch including a backing, a pressure-sensitive adhesive layer formed on one surface of the backing, and a liner having a thickness of T and laminated on the pressure-sensitive adhesive layer, in which the liner has a groove formed from the surface opposite to the surface on which the pressure-sensitive adhesive layer is laminated and having a depth of from T/2 to less than T, the groove has a planar shape which enables the liner to be divided into two or more liner pieces by the groove, and the liner has a bending resistance before forming the groove of 50 mm or more.

Abstract: A reduced pressure dressing for applying reduced pressure treatment to a tissue site includes an interface layer adapted to be positioned at the tissue site. An absorbent layer is in fluid communication with the interface layer to absorb liquid from at least one of the interface layer and the tissue site. A pump is in fluid communication with the absorbent layer to deliver a reduced pressure to the tissue site. A cover is positioned over the pump, the absorbent layer, and the interface layer to maintain the reduced pressure at the tissue site, and a liquid-air separator is positioned between the absorbent layer and the pump to inhibit liquid from entering the pump.

Abstract: A dressing for an open wound includes a cover layer dimensioned for positioning relative to a wound bed. The cover layer permits an evacuation of the space around the wound bed such that a sub-atmospheric pressure may be established to stimulate healing and facilitate the removal of fluid from the wound. Multiple performance zones in the cover layer allow the wound dressing to remain in position through repeated cycles of evacuation without placing undue strain on the wound bed. An outer peripheral zone may include a high peal-strength adhesive while an intermediate zone may include a shear resistant adhesive. A central zone may be devoid of any coating to maximize moisture transmission through cover layer.

Abstract: A topical product including but not limited to a feminine hygiene product or incontinence shield which contains at least two kinds of particulate metals distributed throughout which, when in contact with moisture, form a galvanic current (virtually if not completely imperceptible to the user) that has antimicrobial effect on all pathogens. Galvanic current virtually or completely imperceptible to the user facilitates antimicrobial effect.

Abstract: A layered product comprising an adhesive dressing allowing transfer of one or more elements, e.g. elements containing an active substance or a hydrogel, to the adhesive surface of the adhesive dressing immediately before the adhesive dressing is applied to the surface, e.g. the skin, of a living being.

Abstract: A photoactivated antimicrobial wound dressing comprising a photocatalytic membrane is provided. The photocatalytic membrane comprises a bacterial cellulose hydrogel membrane having photocatalytic particles are immobilized within the membrane and are activated when exposed to light, at which time they react with oxygen-based species forming reactive oxygen species. The reactive oxygen species further react with microbes to kill the microbes.

Abstract: A wound dressing product, combining both a traditional dressing with a mounted absorbent material and a hydrophobic fabric attached thereto, which is to be placed towards the wound, and is capable of binding unwanted microorganisms. The wound dressing product protects the wound, absorbs exudate and reduces the number of pathogenic microorganisms, without using antimicrobial substances, and consists of three bonded layers: hydrophobic cellulose acetate fabric which binds microorganisms, an attached efficient absorbent material, and a backing (cover) which is preferably visually transparent, semi-permeable and self-adhesive.

Abstract: The present invention comprises methods and compositions for making a silver-containing antimicrobial hydrophilic material. More particularly, the present invention comprises methods and compositions for stabilized silver antimicrobial devices comprising a matrix comprising a polymer network and a non-gellable polysaccharide, and an active agent. The matrix may be formed into any desired shape for its desired uses.

Abstract: The invention relates to a transdermal therapeutic system (10) comprising a pharmaceutical active agent formulation (13), an adhesive layer (11) comprising a contact surface (12), and at least one ultrasound transmitter (21), the side of the ultrasound transmitter opposing the contact surface being directly or indirectly adjacent to the pharmaceutical active agent formulation. The transdermal therapeutic system is a multi-layered laminate, one of the laminate layers comprising the ultrasound transmitter, another comprising the adhesive layer, and another comprising the pharmaceutical active agent formulation. Furthermore, from a top view, at least in a plane position of the transdermal therapeutic system, all of the laminate layers (11, 21, 14) are at least approximately mutually congruent and are at least approximately the size of the contact surface.

Abstract: An adhesive hydrogel dressing as well as to methods of applying the dressing to a patient is described. The dressing generally comprises an adhesive hydrogel pad, a backing layer, and an adhesive layer on the backing layer facing the hydrogel pad. The adhesive layer and backing layer form a perimeter around the hydrogel pad and hold the hydrogel pad in place on an application surface. The adhesive hydrogel pad is formed with at least a portion of the perimeter of the hydrogel pad tapered proximate the area that the hydrogel pad and release liner separate during liner removal.

Abstract: An antimicrobial coating is provided for use on textiles, medical devices, packaging materials, and the like. The antimicrobial coating includes a halogenated furanone.

Abstract: A method and apparatus for reducing or eliminating pain after surgical procedures related to mucosal tissue, including tonsillectomy, adenoidectomy, or other pharyngeal operations. Certain embodiments provide a biodegradable film or covering that serves as a mechanical barrier to reduce pain caused, for example, by friction between solid food and healing tissue in the first few days after surgery. Some embodiments may include one or more therapeutic substances for locally reducing pain, facilitating healing and/or otherwise treating mucosal tissue at or near a tonsil bed.

Abstract: A reduced pressure dressing coated with biomolecules including a polymer material layer and at least one biomolecule selected from the group consisting of a hemostatic agent, an antioxidant agent, and a nitric oxide promoter, the at least one biomolecule absorbed into a portion of the polymer material layer. The present reduced pressure dressing coated with biomolecules further includes methods for making same.

Abstract: Methods of use of a multi-layer wrap, for providing more comfortable gel treatment to skin and pressure therapy for underlying skin, the wrap allowing for migration of moisture away from the skin while providing compressive musculo-skeletal support to the treatment site.

Abstract: A therapeutic compound, methods and applicators to prevent and treat focal tissular lesions and infections in mammals is made by the mixture of an antiseptic powder and an antiseptic liquid, wherein the compound may be employed for an “assisted integration” through the “bone socket arrangement” pre or post-implantation by medication in a patient, for preventing or curing by direct contact diseases within the mouth and also to treat skin inflammations, infections, aphthas, herpes simplex infections, ulcers, burns, and other externally illness, to promote healing and bone growth and to chemical debridement.

Abstract: A skin treatment system includes a flexible panel having an outer surface and an inner surface. The flexible panel may be configured to surround at least a portion of a user's appendage. The skin treatment system may also include at least one skin treatment insert having an inner surface and an outer surface. The flexible panel may be further configured to releasably engage the skin treatment insert. The skin treatment insert may be configured to receive a topical skin treatment. The inner surface of the skin treatment insert may be configured to apply the topical skin treatment to at least a portion of a surface of the user's appendage.

Abstract: A wound dressing composition and a method of using that composition to enhance the protection and isolation of a minor wound. The composition contains at least one ingredient selected from mature Bamboo stalk pulp or derivatives thereof, an adhesive that adheres to skin selected from the families of synthetic and natural elastomers and a hydrophilic compound.

Abstract: An epidermal lifting mechanism (10) comprising at least one strip of flexible material (50), first and second end portions (60), a middle portion (70), adhesive material (40), a plurality of resilient spring structures (20, 22, 24) extending through the at least one strip of flexible material, and a flap mechanism (80) integral with the middle portion.

Abstract: A wound dressing composition comprising a partially cured polyurethane fluid. The composition can be injected directly into a wound, where it cures to form a wound filling dressing. Also provided is a wound dressing comprising such a composition. Also provided is a kit for the preparation of such wound dressings, the kit comprising (a) a polyurethane prepolymer; and (b) a curing agent for the polyurethane prepolymer. Preferably, the polyurethane components comprise reaction products of a diisocyanate with castor oil or a related ester of ricinoleic acid or its derivatives.

Abstract: A vacuum bandage is provided for use with a wound having a wound surface. The bandage is connectable to a vacuum source and includes a wound dressing member having a wound contacting surface, a top surface, and a port configured for communication with the vacuum source. The wound dressing member further includes holes in the wound contacting surface configured for communication with the wound surface of the wound and a passageway between the port and each hole. The vacuum bandage further includes a pack adjacent to the top surface of the member. The pack may include an aperture positioned about the port.

Abstract: The invention relates to a medical dressing having an elastic material for encircling about a body member, an elastomer attached to the elastic material and adapted to directly contact a wound on the body member, and where the elastomer includes an additive for treating the wound, wherein the elastic material applies compressive force to the elastomer and wound as the elastic material encircles the body member.

Abstract: The present disclosure relates to dressings, such as patches and bandages, and other devices and systems that deliver nitric oxide.

Abstract: A tissue treatment device suitable for use on an extremity or a portion of an extremity, such as a hand or foot, includes a cover formed as a bag, sac, or pouch, and a flexible, absorbent support member. Defined sections of the support member may be removed from the support member to form an opening therein. The support member is for being positioned within the cover to support a portion of the cover off of, and out of contact with, tissue to be treated. The cover has an open end with attachment means disposed thereon for attachment to the extremity or extremity portion that is received in the cover. The support member may be impregnated with a medicament. The removable sections allow formation of an opening that may be customized or adapted to the area of tissue that is to receive treatment. This permits the tissue treatment device to be adapted for use with treatment areas that vary in size, shape, contour, and composition.

Abstract: A wound dressing including a backing layer, an adhesive layer and an absorbent layer between the backing layer and the adhesive layer, in which the adhesive layer secures the absorbent layer to the backing layer and the adhesive layer is interrupted in at least one zone exposing at least a part of the skin contacting surface of the absorbent layer. At least the skin-facing surface of the adhesive layer is provided with a non-detachable, non-adhesive cover layer.

Abstract: Hydrophilic compositions are described, which are prepared from a first oligomer containing pendent polymerizable groups and pendent hydrophilic groups, crosslinked with a co-reactive second component oligomer possessing photoinitiator groups. The compositions may be used as in preparation of hydrophilic gel coatings or layers for medical devices.