Having Means For Cooling Or Heating Body, Treating Or Collected Material Or Device Patents (Class 604/113)
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Patent number: 8372047Abstract: A system and method of topically applying an anesthetic, or other medication, to one or both lips of the mouth. An applicator device is provided that has a curved first wall, a curved second wall, and a horizontal shelf that joins the first wall to the second wall. The first wall, the second wall and the horizontal shelf combine to define either one or two curved lip compartments. A volume of the anesthetic, or other medication, is placed within the curved lip compartments. The applicator device is partially placed in a person's mouth so that the second wall is positioned between the back of the lips and in front of the teeth. While in this position, the lip of the user passes into the curved lip compartment and is contacted by the anesthetic.Type: GrantFiled: February 2, 2011Date of Patent: February 12, 2013Inventor: Otto J. Placik
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Patent number: 8366665Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature.Type: GrantFiled: February 15, 2008Date of Patent: February 5, 2013Assignee: Micrus CorporationInventors: Peter Wilson, Eric Leopold, Rupesh K. Desai
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Patent number: 8353870Abstract: This disclosure relates to medical temperature sensors and related systems and methods. In some aspects, a sensor assembly includes a non-invasive temperature sensor to detect a temperature of a medical fluid in a medical fluid line and an ambient temperature sensor to detect an ambient air temperature.Type: GrantFiled: April 26, 2011Date of Patent: January 15, 2013Assignee: Fresenius Medical Care Holdings, Inc.Inventors: Roland Levin, Martin Joseph Crnkovich
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Publication number: 20130011332Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.Type: ApplicationFiled: September 14, 2012Publication date: January 10, 2013Applicant: Searete LLC,Inventors: Edward S. Boyden, Daniel B. Cook, Roderick A. Hyde, Eric C. Leuthardt, Nathan P. Myhrvold, Elizabeth A. Sweeney, Lowell L. Wood, JR.
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Patent number: 8343097Abstract: Methods and systems for infusing a cooled infusate to a target location in a patient are described. A temperature of the blood and infusate admixture upstream of the catheter as well as at other locations along the catheter may be monitored and a feedback system utilized to control the volume, temperature, and/or infusion rate of the infusate so as to achieve a predetermined temperature at the target location. Control may also be based on the patient's native vessel flow rate. The system may monitor or calculate hematocrit upstream of the catheter and adjust infusion so as to provide sufficient oxygenation of the blood and infusate admixture. The system may also monitor reflux of the infusate past a distal end of the catheter and reduce infusion upon the detection of reflux.Type: GrantFiled: June 20, 2008Date of Patent: January 1, 2013Assignee: Hybernia Medical LLCInventors: John Pile-Spellman, Erwin Lin
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Publication number: 20120330233Abstract: Herein disclosed is a system for applying shear stress ex-situ to a fluid. In some embodiments, the system comprises a shear device; and at least one device configured for intravenous administration of the fluid to a patient, the devices defining a fluid passage configured to be sterilized and maintained sterile during use, the fluid comprising at least one therapeutic fluid, blood, or a combination thereof. The shear device of the system is in fluid communication with the at least one device configured for intravenous administration of the fluid to a patient. Herein also disclosed is a method of preparing a fluid for intravenous administration to a patient.Type: ApplicationFiled: July 26, 2012Publication date: December 27, 2012Applicant: H R D CorporationInventors: Abbas Hassan, Rayford G. Anthony, Gregory G. Borsinger, Aziz Hassan
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Publication number: 20120323169Abstract: The present invention relates to an apparatus for heating a medical fluid, a method for heating a medical fluid, and a blood treatment device.Type: ApplicationFiled: June 11, 2012Publication date: December 20, 2012Applicant: Fresenius Medical Care Deutschland GmbHInventor: Christoph WIKTOR
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Publication number: 20120310151Abstract: Embodiments of the present technology include a micromachined implantable drug delivery devices, grippers, and syringes that are wirelessly powered and controlled by frequency tuning of external radiofrequency (RF) magnetic fields. An illustrative device can be designed and constructed with passive circuitry and microvalves that operate without batteries, e.g., through thermal actuation of hydrogel microvalves and/or shape-memory alloy members. The frequency selectivity in the device control provides not only a path to achieving reliable and safe operation of drug delivery but also potential applications for selective delivery of multiple drugs.Type: ApplicationFiled: December 13, 2011Publication date: December 6, 2012Inventors: Kenichi Takahata, Mohamed Sultan Mohamed Ali, Somayyeh Rahimi
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Publication number: 20120302995Abstract: A system for perfusing a localized site within a body includes a catheter assembly having a venous access line that is adapted to deliver perfusate to the localized site, a venous or arterial drainage line adapted to drain perfusate from the localized site, and an occlusion device adapted to prevent some or substantially all physiological blood flow between the localized site and the systemic circulation of the body during and in the course of perfusing and draining perfusate to and from the localized site. The system may include a blood circuit associated with the catheter assembly to facilitate blood conditioning for use as the perfusate, in the course of a controlled perfusion and/or drainage of untreated, treated, or inactivated treated blood to and from the localized site.Type: ApplicationFiled: February 2, 2011Publication date: November 29, 2012Inventor: Pramote Hochareon
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Publication number: 20120296280Abstract: The micro needle includes a needle and a body. The needle includes an inclined part including an inclined outer wall, a straight part including a straight outer wall, and a recess having a certain depth along the inclined or straight outer wall. The body is coupled to the needle to move or support the needle. The micro needle apparatus includes a micro needle head part, an infrared generator part, and a power supply part. The micro needle head part includes a plurality of micro needles having front ends protruding out of the micro needle head part. When the micro needles are pressed against a skin, the micro needles arrive at a dermis of the skin. The infrared generator part generates an infrared or far infrared ray to the skin through an inside or outside of the micro needle. The power supply part supplies energy required for the infrared generator part.Type: ApplicationFiled: January 28, 2011Publication date: November 22, 2012Applicant: U-BIOMED INCInventor: Nyeon Sik Eum
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Patent number: 8313461Abstract: A kit of parts comprises a system and instructions for use for controlling patient temperature which uses a central venous line catheter having a heat exchange element. The central venous line catheter is provided with one or more lumens for providing access to the central blood supply of the patient and with additional lumens for communicating heat exchange fluid to the heat exchange element. Heat exchange fluid temperature is controlled through a feed back loop iii which patient temperature is sensed and used to control a temperature control unit comprising a heating device and/or a cooling device in heat exchange relationship with the heat exchange fluid. A tubing set transports the heat exchange fluid between the central venous line and the temperature control unit, with a pump serving to circulate the fluid in a closed fluid circuit in the system.Type: GrantFiled: January 16, 2008Date of Patent: November 20, 2012Assignee: Zoll Circulation, Inc.Inventors: Blair D. Walker, Scott M. Evans, David P. Baiding, Peter Barker
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Patent number: 8313460Abstract: Devices, systems and methods for controlling fluid temperatures from more than one fluid containers prior to their infusion into a human body are disclosed. The device includes a power supply source for providing power; an input/output interface for receiving fluid temperature data from thermal sensors and for transmitting duty-cycle signals to each of the fluid warming unit; a processing unit for comparing fluid temperature data with a permissible fluid temperature range, for calculating a fluid temperature differential, and for apportioning the available work cycle of the power supply source; and a controller for adjusting the duty-cycle of each fluid warming unit based on the fluid temperature differentials, so that during each work cycle all available power provided by the power supply source is delivered to only one of the fluid warming units at a time.Type: GrantFiled: March 21, 2006Date of Patent: November 20, 2012Assignee: General Electric CompanyInventor: David E. Cassidy
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Publication number: 20120289900Abstract: An automated reservoir filling system for a portable medical device is disclosed. The system includes a vial sealed by a septum partially filled with a liquid and a gas occupying a headspace. The system further includes a reservoir with a volume defined between a reservoir septum and a plunger head. The plunger head is coupled to a plunger arm which is further coupled to a drive system. Further included is a transfer system with a vial end that pierces the vial septum and remains in contact with the liquid, and a reservoir end that pierces the reservoir septum and remains in the reservoir volume. A controller coupled to the drive system to actuates the drive system automatically drawing fluid from the vial to the reservoir through the degas system.Type: ApplicationFiled: May 9, 2012Publication date: November 15, 2012Applicant: MEDTRONIC MINIMED, INC.Inventors: Colin A. Chong, Arsen Ibranyan, Eric M. Lorenzen, Edgardo C. Halili
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Publication number: 20120288848Abstract: A three dimensional dome wrap or pad for direct patient surface tissue applications for symmetrical dome shaped anatomy and extremities is disclosed herein. The pad of the present invention comprises a system of smooth streamline mathematically configured channels throughout one or more similarly shaped panels or lobes bonded distinctively to make one unit for the purpose of temperature management of three dimensional objects or subjects when it is applied or inserted.Type: ApplicationFiled: January 20, 2012Publication date: November 15, 2012Applicant: TRAUMATEC, INC.Inventors: Jeffrey W. Latham, Randall D. Manteufel, Nolan P. Manteufel
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Publication number: 20120277673Abstract: This disclosure relates to medical temperature sensors and related systems and methods. In some aspects, a sensor assembly includes a non-invasive temperature sensor to detect a temperature of a medical fluid in a medical fluid line and an ambient temperature sensor to detect an ambient air temperature.Type: ApplicationFiled: April 26, 2011Publication date: November 1, 2012Applicant: FRESENIUS MEDICAL CARE HOLDINGS, INC.Inventors: Roland Levin, Martin Joseph Crnkovich
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Publication number: 20120271271Abstract: A heating system for warming nutritional liquid fed to a neonate or preterm infant may comprise a control module and a heater. The heating system is portable so that the heating system is not connected to a syringe pump or other device used to feed the neonate. The heater of the heating system is mounted to the tube that is used to feed the neonate. The heater is positioned along the tube in close proximity to the neonate so that a temperature drop of the nutritional liquid after the nutritional liquid exits the heater and reaches the neonate is negligible. The heater raises the temperature of the nutritional liquid to a target desired temperature (e.g., body temperature of the mother and neonate or to a temperature above the temperature of the mother and neonate) so that the neonate may consume warm nutritional fluid. Once the nutritional liquid reaches the neonate, the nutritional liquid is at about the body temperature of the mother or neonate or at least above room temperature.Type: ApplicationFiled: April 22, 2011Publication date: October 25, 2012Inventors: Dongchul D. Hyun, Michael Fleury
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Publication number: 20120266876Abstract: The invention relates to a medicament container (2), comprising a bag (3) with an outlet (4), the bag (3) compressible by a compression means (6), the bag (3) having an inner surface arranged to stick when subjected to the compression means (6). The invention also refers to an arrangement (1) for administering a liquid medicament (M) comprising the medicament container (2) and a compression means (6) for locally compressing the bag (3).Type: ApplicationFiled: August 20, 2010Publication date: October 25, 2012Applicant: SANOFI-AVENTIS DEUTSCHLAND GMBHInventors: Thomas Nagel, Rene Richter, Robert Witt
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Publication number: 20120265137Abstract: An apparatus for treatment of tissue within a body requiring thermotherapy includes a catheter to be inserted into a bodily conduit, an energy-emitting source disposed within the catheter, a compression balloon surrounding the energy-emitting source where the compression balloon has an inflated diameter that is greater than that of the bodily conduit in a relaxed state and an outside surface of the balloon is coated with one of gene modifiers and drug or medication, and means for activating the energy-emitting source to radiate energy to heat the drug-coated compression balloon and tissue to be treated whereby the heated drug-coated compression balloon effectively delivers the one of the gene modifiers and drug or medication to a target area of the diseased tissue. In addition, methods for using the above apparatus to treat diseased tissue are disclosed.Type: ApplicationFiled: June 14, 2012Publication date: October 18, 2012Applicant: BOSTON SCIENTIFIC CORPORATIONInventor: John MON
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Publication number: 20120253282Abstract: The invention relates to a medicament container for a liquid medicament, the medicament container comprising a bag with an outlet, the bag being compressible or shrinkable by subjection of at least a part of the medicament container to an energy source.Type: ApplicationFiled: August 20, 2010Publication date: October 4, 2012Applicant: Sanofi-Aventis Deutschland GmbHInventors: Thomas Nagel, René Richter, Robert Witt
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Patent number: 8257340Abstract: Heat transfer catheter apparatus and methods of making and using same are disclosed wherein fluid connection means is provided between the distal portions of two adjacent, thin-walled, high strength fluid lumens to define a closed loop fluid circulation system capable of controlled delivery of thermal energy to or withdrawal of thermal energy from remote internal body locations.Type: GrantFiled: October 8, 2010Date of Patent: September 4, 2012Assignee: Advanced Polymers, Inc.Inventor: Mark A. Saab
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Publication number: 20120220938Abstract: A compact and highly efficient intravenous fluid heater includes a heat exchanger assembly, sensors for sensing respective temperatures of entering and exiting fluids of the flow path, a controller for controlling the heat generated by the heat exchanger assembly, based upon the temperatures of the exiting fluids, heating of the fluid in the flow path by the heating element so as to cause the fluid in the flow path to be substantially uniformly heated to a desired infusion temperature prior to exiting the heater. The heat exchanger assembly uses thin film heating elements having a predetermined set temperature and that transfers heat directly to a standard intravenous tube coil wrapped around the battery housing. The intravenous fluid heater is located in a housing with the intravenous fluid lines extending there from for standard connection with an intravenous line or source of intravenous fluid.Type: ApplicationFiled: June 9, 2011Publication date: August 30, 2012Applicant: NORTH AMERICAN RESCUE, LLCInventors: Darrel Burton Saunders, Robert Charles Echlin
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Publication number: 20120220937Abstract: A method that includes conveying overheated dialysate through a cassette in a manner to reduce the temperature of the overheated dialysate, and a dialysis system including a control unit configured to cause overheated dialysate to be conveyed through a cassette in a manner to reduce the temperature of the overheated dialysate.Type: ApplicationFiled: May 4, 2012Publication date: August 30, 2012Applicant: FRESENIUS MEDICAL CARE DEUTSCHLAND GMBHInventors: Frank Hedmann, Stephan Klatte
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Publication number: 20120209177Abstract: A therapeutic rinse for treating a sore throat including a self heating container having a reservoir. The self heating container is capable of reaching a temperature of at least 130 degrees Fahrenheit when activated. The therapeutic rinse includes a liquid composition having sodium chloride, water, an antibiotic, and a variety of vitamins, minerals and herbs stored in the reservoir of the self heating container. During use, the self heating container is activated and the liquid composition is heated inside the reservoir to about 130 degrees Fahrenheit.Type: ApplicationFiled: February 13, 2012Publication date: August 16, 2012Inventor: Juliet Agatha Boghossian
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Publication number: 20120203164Abstract: The present invention relates to a device and method for the controlled delivery of a drug to a targeted layer of the skin in a human or animal subject. In particular, the present invention relates to such a device, system and method for selective drug delivery to the cutaneous or subcutaneous layer of skin to enhances the effectiveness of the drug delivery.Type: ApplicationFiled: October 4, 2010Publication date: August 9, 2012Inventors: Gabriel Bitton, Ron Nagar, Benny Pesach
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Publication number: 20120191069Abstract: A pump for delivering a fluid, created by cooling and pressurizing a fluid, into the intrathecal space of a patient, the pump comprising an input channel, an input reservoir in fluid communication with the input channel, a cooling apparatus configured to remove heat from the fluid and a pressurizing mechanism configured to impart pressure to the fluid, an output reservoir, and an output channel, and wherein the output channel is configured to be in fluid communication with a first lumen of a catheter and wherein the first lumen of the catheter is configured to be disposed within the intrathecal space of the patient.Type: ApplicationFiled: July 19, 2011Publication date: July 26, 2012Inventor: Jeffrey E. Thomas
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Patent number: 8226605Abstract: An IV line temperature controlled warming device includes a housing and a fluid cassette or cartridge that receives fluid from an IV line and includes intravenous line tubing arranged in a preformed configuration. The configuration includes tubing sections arranged in generally circular and concentric portions and a central serpentine tubing section that basically reverses fluid flow and facilitates flow in opposing directions within adjacent tubing sections. The fluid cassette is retained within the device on a base plate partially disposed within a device housing interior, while a housing cover is selectively opened and closed to permit access to the base plate. The base plate includes a heater plate disposed thereon, while the cover and heater plate each include heating elements to apply heat to opposing surfaces of the tubing cassette. The heating elements are controlled by a controller in response to measured temperatures of the heater plate and fluid.Type: GrantFiled: December 17, 2001Date of Patent: July 24, 2012Assignee: Medical Solutions, Inc.Inventors: Durward I. Faries, Jr., Bruce R. Heymann, Calvin Blankenship, David Hendrix
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Patent number: 8224166Abstract: A liquid heating bag 50 is proposed, in particular, a blood heating bag, with a flow volume 1 that is formed from at least two flexible plastic foils connected to each other by welding at four delimiting edges 3,4,5,6, has a flat, substantially trapezoidal basic shape that is limited by the delimiting edges 3,4,5,6, and an inlet line opening 10 and an outlet line opening 11 for a liquid to be heated that are disposed at an upper delimiting edge 3 of the delimiting edges 3,4,5,6 to be disposed at the top during liquid heating, wherein the upper delimiting edge 3 extends sufficiently obliquely with respect to its adjacent delimiting edges 4,6 that a gas reception volume 8 is formed in the region of an acute angle of the flow volume 1 subtended between the upper delimiting edge 3 and a delimiting edge 6 adjacent thereto, and a liquid flow guiding seam 13 that is formed by connecting the plastic foils in the region of the flow volume 1 and divides the upper delimiting edge 3 into a lower inlet line opening regionType: GrantFiled: July 23, 2009Date of Patent: July 17, 2012Assignee: WWT Technischer Geraetebau GmbHInventors: Wolfgang Theilacker-Beck, Matthias Theilacker, Klaus Schmider
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Patent number: 8224455Abstract: A method and apparatus of treating tissue adjacent a bodily conduit using thermotherapy, while preventing obstructions of the bodily conduit due to edema, includes injection of a drug-encapsulated within a heat-sensitive carrier, such as a liposome, within a region of tissue to be treated. The heat produced by the energy-emitting source heats a portion of the tissue surrounding the bodily conduit to a temperature of approximately 43° C. for a time sufficient to destroy the heated portion of the tissue. In addition, the heat produced by the energy-emitting source activates the heat-sensitive carrier to activate the release of the encapsulated drug and the drug targets the tissue to be heated. The focused energy of the energy-emitting source together with the compression acting on the target area can assist in delivering drugs to the target area so that a natural stent has a long term efficacy.Type: GrantFiled: October 12, 2010Date of Patent: July 17, 2012Assignee: Boston Scientific CorporationInventors: John Mon, Alan J. Fenn
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Patent number: 8216183Abstract: A heating device (1) is described for a container (7) of a liquid pharmaceutical product having a viscosity of 50-500 cP at 4° C. and contained within a glass container. The device (1) comprises a substantially rigid, thin-walled housing (2) defining an openable chamber for receiving the container (7), a heat source (6) in the chamber comprising a hermetically sealed package containing a super-cooled metal salt fluid or liquid and an actuator (14) for activating the super-cooled metal salt to produce heat, wherein the ratio of the volume of the metal salt to the intended volume of the product is no more than 1:1.Type: GrantFiled: July 21, 2008Date of Patent: July 10, 2012Assignee: Norbrook Laboratories LimitedInventors: William Blakeley, Michael Lanigan, Lillian Cromie
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Patent number: 8211052Abstract: A charged hydration device and a method of filling the hydration device so the charged hydration that can be mounted to a medical apparatus that provides insufflation fluid to a body cavity either immediately prior to the medical procedure or during a medical procedure with the charged hydration device including an inlet and outlet for an inline connection with the medical apparatus so that an insufflation gas delivered through the charged hydration device is hydrated to prevent tissue damage to a person receiving the insufflation gas.Type: GrantFiled: July 13, 2006Date of Patent: July 3, 2012Assignee: Lexion Medical LLCInventors: Douglas E. Ott, Robert I. Gray, Duane Lloyd
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Patent number: 8206332Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.Type: GrantFiled: June 7, 2010Date of Patent: June 26, 2012Assignees: Zoll Circulation Inc., The Regents of the University of CaliforniaInventors: Wayne A. Noda, Mike L. Jones, Scott M. Evans, Blair D. Walker, William J. Worthen, Yves Pierre Gobin
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Patent number: 8206337Abstract: This invention relates to apparatus used to heat, humidify and filter insufflated gases to alter the temperature and humidity of gases prior to delivering the gases into a patient The apparatus includes an insufflator, humidifier and gas transportation conduit connected to gas delivery tubing to deliver humidified and heated gases to a body cavity prior to and during a medical procedure. The insufflator an humidifier are contained in the one housing, enabling the housing to be located remote from an operating table. The gas transportation conduit delivers the humidified gases to the body cavity in a flexible tubing having located within, throughout or around it heating apparatus enabling the gas temperature and humidity levels to be maintained from the housing to the patient.Type: GrantFiled: October 15, 2001Date of Patent: June 26, 2012Assignee: Fisher & Paykel Healthcare LimitedInventors: Michael Joseph Blackhurst, Nina Caroline Batty, Daniel John Smith, Hussein Kadhum
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Patent number: 8197452Abstract: A vascular access device may include a body and a layer of the body that communicates with a pathogenic environment to discourage adhesion of a pathogen to the layer and thus repress pathogenic activity. A method of repressing pathogenic activity in a vascular access device includes providing the device with a body, and coating the body with a layer that discourages adhesion of a pathogen to the layer.Type: GrantFiled: July 26, 2007Date of Patent: June 12, 2012Assignee: Becton, Dickinson and CompanyInventors: Weston F. Harding, Austin Jason McKinnon, Mark A. Crawford, Lantao Guo, Glade H. Howell, David Ou-Yang
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Patent number: 8192392Abstract: Systems and methods for selective cooling of a target site include a catheter having a supply lumen and a delivery lumen, with inlet and exit ports. Blood is withdrawn from the supply lumen and cooled or heated in a control unit. The treated blood is sent to the targeted area via delivery lumen. The supply lumen can act as an insulator for the delivery lumen.Type: GrantFiled: September 5, 2010Date of Patent: June 5, 2012Assignee: ThermopeutiX, Inc.Inventors: Ronald J. Solar, Glen Lieber
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Patent number: 8177746Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature.Type: GrantFiled: February 15, 2008Date of Patent: May 15, 2012Assignee: Micrus CorporationInventors: Peter Wilson, Eric Leopold, Rupesh K. Desai
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Patent number: 8180206Abstract: An infusion unit includes a heating unit with opposed heating plates. A heat exchanger has a fluid flow path receivable between the heating plates to which heat is conducted by contact with the heating plates. Infusate flowing under pressure through the fluid flow path is heated by conduction from the heating plates through the fluid container. When the flow of infusate is stopped or interrupted, infusate trapped in the heat exchanger is displaced to a reservoir in the heat exchanger. Displacement of the trapped infusate reduces friction between the fluid container and the heating plates, which assists in extraction of the heat exchanger from the heating unit.Type: GrantFiled: April 22, 2008Date of Patent: May 15, 2012Assignee: Arizant Healthcare Inc.Inventors: Mark T. Bieberich, Melanie L. Collins, Gary L. Hansen, Andrew J. McGregor, Christopher A. Miller, Donald E. Stapf, Winston T. Tan
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Patent number: 8177747Abstract: Disposable injection devices are disclosed herein. In an exemplary arrangement, the disposable injection device comprises an annular sleeve, a predetermined pre-injection quantity of a substance configured for selective injection, and a temperature control element. The annular sleeve at least partially defines a dispensing chamber therein. The predetermined pre-injection quantity of the substance configured for selective injection is disposed within the dispensing chamber. The temperature control element is operably connected to the dispensing chamber, and is configured to selectively heat the substance to a predetermined temperature. The substance expands from the pre-injection quantity at the predetermined temperature to an injection quantity whereby the injection quantity is greater than a volume defined by the dispensing chamber. In this manner, a predetermined minimum quantity of the substance is self-expelled from the dispensing chamber.Type: GrantFiled: November 30, 2010Date of Patent: May 15, 2012Assignee: Alcon Research, Ltd.Inventor: Raffi S. Pinedjian
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Patent number: 8167838Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature.Type: GrantFiled: February 15, 2008Date of Patent: May 1, 2012Assignee: Micrus CorporationInventors: Peter Wilson, Eric Leopold, Rupesh K. Desai
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Patent number: 8167839Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature.Type: GrantFiled: July 30, 2009Date of Patent: May 1, 2012Assignee: Micrus CorporationInventors: Peter Wilson, Eric W. Leopold, Rupesh K. Desai
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Patent number: 8162971Abstract: A vasoocclusive coil is reinforced with a stretch resistant member to improve safety during retraction of the coil. The stretch resistant member is fixedly attached at one end to the vasoocclusive coil, and the other end of the stretch resistant member is detachably mounted to an elongated pusher member to allow for placement and release of the vasoocclusive coil within the patient's vasculature.Type: GrantFiled: February 15, 2008Date of Patent: April 24, 2012Assignee: Micrus CorporationInventors: Peter Wilson, Eric Leopold, Rupesh K. Desai
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Patent number: 8150244Abstract: A fluid warming device includes axially or longitudinally slidable covers that retain a removable heat exchange body in a housing in heat exchange communication with a heater assembly while allowing flow through the heat exchange body to be observed. In another aspect, a fluid warming system increases or decreases power to a heater assembly to adjust the fluid temperature to ensure that the fluid is at an appropriate temperature when it reaches the patient.Type: GrantFiled: January 3, 2011Date of Patent: April 3, 2012Assignee: General Electric CompanyInventor: David E. Cassidy
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Publication number: 20120078223Abstract: A warming garment and method of making and using are provided. The warming garment may have an inner lining and an outer lining which may form an annular space in which an exothermic composition that is activated upon exposure to oxygen may be disposed. When worn, the warming garment may aid in inducing vasodilation upon a subject's limb through the emanation of heat from the exothermic composition. Once vasodilation is achieved, venipuncture or catheter insertion procedures may be properly initiated.Type: ApplicationFiled: November 30, 2010Publication date: March 29, 2012Inventor: Joan E. Spiegel
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Publication number: 20120078229Abstract: The present invention relates to an in vivo method of promoting the growth of autologous cartilage and bone tissue, including tissue that can be explanted to other locations in the subject.Type: ApplicationFiled: December 2, 2011Publication date: March 29, 2012Inventors: Pieter J. Emans, Prasad Venkatram Shastri
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Publication number: 20120059318Abstract: A method for determining a flow rate of a fluid is provided. The method includes heating an aliquot of the fluid at a first position of a fluid-delivery channel, illuminating fluid in the fluid-delivery channel at a second position downstream from the first position, measuring an amount of light reflected from the illuminated fluid to determine a change in the amount corresponding to the heated aliquot passing the second position, and calculating the flow rate of the fluid based upon a distance between the first position and the second position and a time between the heating the aliquot and the heated aliquot passing the second position.Type: ApplicationFiled: September 23, 2011Publication date: March 8, 2012Applicant: CareFusion 303, Inc.Inventor: Paul Dewey
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Patent number: 8128595Abstract: A kit of parts comprises a system and instructions for use for controlling patient temperature which uses a central venous line catheter having a heat exchange element. The central venous line catheter is provided with one or more lumens for providing access to the central blood supply of the patient, and with additional lumens for communicating heat exchange fluid to the heat exchange element. Heat exchange fluid temperature is controlled through a feed back loop in which patient temperature is sensed and used to control a temperature control unit comprising a heating device and/or a cooling device in heat exchange relationship with the heat exchange fluid. A tubing set transports the heat exchange fluid between the central venous line and the temperature control unit, with a pump serving to circulate the fluid in a closed fluid circuit in the system.Type: GrantFiled: August 24, 2001Date of Patent: March 6, 2012Assignee: Zoll Circulation, Inc.Inventors: Blair D. Walker, Scott M. Evans, David P. Balding, Peter Barker
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Publication number: 20120053518Abstract: An IV line temperature controlled warming device includes a housing and a fluid cassette or cartridge that receives fluid from an IV line and includes intravenous line tubing arranged in a preformed configuration. The configuration includes tubing sections arranged in generally circular and concentric portions and a central serpentine tubing section that basically reverses fluid flow and facilitates flow in opposing directions within adjacent tubing sections. The fluid cassette is retained within the device on a base plate partially disposed within a device housing interior, while a housing cover is selectively opened and closed to permit access to the base plate. The base plate includes a heater plate disposed thereon, while the cover and heater plate each include heating elements to apply heat to opposing surfaces of the tubing cassette. The heating elements are controlled by a controller in response to measured temperatures of the heater plate and fluid.Type: ApplicationFiled: November 4, 2011Publication date: March 1, 2012Inventors: Durward I. Faries, JR., Bruce R. Heymann, Calvin Blankenship, David Hendrix
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Patent number: 8118790Abstract: The present invention is an ophthalmic injection system with a limited reuse assembly and a tip segment. The tip segment is connectable to and removable from the limited reuse assembly. The tip segment includes a dispensing chamber, a plunger, and a housing. The dispensing chamber holds a quantity of a substance to be injected into an eye. The proximate end of the plunger has a first mechanical linkage interface. The limited reuse assembly of the ophthalmic injection system has a power source, a controller, a motor, a second mechanical linkage interface located on an end of the motor shaft; and a second housing. The first mechanical linkage interface is mateable with the second mechanical linkage interface such that when the tip segment is connected to the limited reuse assembly, the first mechanical linkage interface mates with the second mechanical linkage interface so that motion of the shaft results in motion of the plunger.Type: GrantFiled: October 9, 2007Date of Patent: February 21, 2012Assignee: Alcon Research, Ltd.Inventors: Bruno Dacquay, Casey Lind, Cesario Dos Santos, Paul R. Hallen
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Publication number: 20120035543Abstract: A system is disclosed. The system includes a fill adapter device including a heat exchanger which includes a heating element and a fluid pathway, the fluid pathway fluidly connected to a filling needle input, whereby fluid enters the heat exchanger through the filling needle input and flows through the fluid pathway and whereby the fluid is heated by the heating element. The system also includes a reservoir including a plunger and a plunger rod and a filling needle configured to be removably attached to the reservoir, wherein the fill adapter is configured to be attached to a vial of fluid and wherein fluid from the vial flows through the fluid pathway and is heated and loaded into the reservoir through the filling needle.Type: ApplicationFiled: February 4, 2011Publication date: February 9, 2012Applicant: DEKA Products Limited PartnershipInventors: DEAN KAMEN, JOHN M. KERWIN, MARC A. MANDRO, KEVIN A. DURAND, LARRY B. GRAY, GREGORY R. LANIER, JR., COLIN H. MURPHY
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Patent number: 8109894Abstract: A catheter is adapted to exchange heat with a body fluid, such as blood, flowing in a body conduit, such as a blood vessel. The catheter includes a shaft with a heat exchange region disposed at its distal end. This region may include hollow fibers which are adapted to receive a remotely cooled heat exchange fluid preferably flowing in a direction counter to that of the body fluid. The hollow fibers enhance the surface area of contact, as well as the mixing of both the heat exchange fluid and the body fluid. The catheter can be positioned to produce hypothermia in a selective area of the body or alternatively positioned to systemically cool the entire body system.Type: GrantFiled: February 4, 2011Date of Patent: February 7, 2012Assignees: Zoll Circulation, Inc., The Regents of the University of CaliforniaInventors: Wayne A. Noda, Mike L. Jones, Scott M. Evans, Blair D. Walker, William J. Worthen, Yves Pierre Gobin
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Patent number: RE43617Abstract: A method and apparatus are disclosed for liquefying target tissue within a body and aspirating the same while leaving non-target tissue intact. A biocompatible fluid is heated and contacted with target tissue so that the target tissue is melted while non-target tissue remains intact. As the target tissue is being melted it is also aspirated from the body.Type: GrantFiled: February 13, 2008Date of Patent: August 28, 2012Inventors: Mark S. Andrew, Mylina Andrew