Abstract: An electroporation device with a needle array removably attached thereto, the needle array having a body, a shroud movable with respect to the body between a rest position and one or more actuated positions, and an auto-lock assembly. Where the auto-lock assembly is adjustable between a locked configuration, where the shroud is not movable with respect to the body, and an unlocked configuration, where the shroud is movable with respect to the body, and where biasing the shroud from the rest position to the one or more actuated positions and back to the rest position adjusts the auto-lock from the unlocked configuration to the locked configuration.

Abstract: Disclosed herein are exemplary medical devices for controlled delivery of material compositions, particularly occlusive, therapeutic, or diagnostic compositions.

Abstract: The present invention relates to a medicament container holder (10) comprising a body (12) adapted to receive a medicament container (14), the body (12) comprising proximally directed tongues (38) at its proximal end, engagement elements (42) arranged at the proximal end of the tongues (38), directed inwards, which engagement elements (42) are arranged to engage a neck portion (46) of the medicament container (14); wherein the tongues (38) deflect radially outwards when engaged by a needle shield (16) of said medicament container (14). The invention is characterized in that said tongues (38) with said engagement elements (42), engage with said neck portion (46) of said medicament container (14) for preventing the medicament container (14) from moving in a proximal direction relative the medicament container holder (10), when disengaged with said needle shield, wherein said tongues (38) are in a stressed state when in engagement with said neck portion (46).

Abstract: An assembly for forming an injection device, comprising: a foot to be placed on a skin; a body comprising at least one needle, the body being movably mounted to the foot for allowing movement of the needle towards the skin, the needle extending out of a second contact surface by a predefined distance for limiting a penetration depth of the needle; first friction means for preventing movement of the body relative to the foot for causing a sudden acceleration; the assembly further comprising second friction means for creating a dynamic friction when the needle is moving towards the skin for keeping the skin stretched.

Abstract: Disclosed is an auto-injection apparatus for receiving a syringe, including: an outer casing enclosing a drive assembly and a syringe carrier configured to hold a barrel of the syringe, the syringe carrier being forward of the drive assembly and having stowed and delivery positions; an interlock extending between the syringe carrier and a syringe carrier housing at least partially surrounding the syringe carrier, the interlock preventing forward motion of the syringe carrier under the influence of an insertion actuator whilst in the stowed position. The drive assembly includes the insertion actuator for inserting a needle of the syringe into an injection site and a delivery actuator for driving a plunger into a barrel of the syringe which contains a substance for injection. The syringe carrier includes an interlock release mechanism which is configured to release the interlock such that the insertion actuator drives the syringe carrier forward.

Abstract: Disclosed is an injection device including a body for receiving a syringe, a firing mechanism including a reaction component, a plunger configured to be axially displaced in a forward direction relative to the reaction component, and a drive spring located between the reaction component and the plunger for driving the plunger forwards upon activation of the injection device, wherein the reaction component provides a reaction surface for the drive spring. The device further includes a locking mechanism for locking the reaction component in a first axial position within the body, the locking mechanism being configured to release the reaction component upon a predefined forward movement of the plunger thereby allowing the reaction component to be driven in a rearward axial direction by the drive spring until it impacts against the body or a component secured to the body to thereby emit an audible indication of an end of dose.

Abstract: The present disclosure relates to a safety mechanism for a medicament delivery device for mechanical shock absorption, which safety mechanism has a medicament delivery member sleeve, a housing having a proximal opening arranged to receive the medicament delivery member sleeve, wherein the medicament delivery member sleeve is axially displaceable inside the housing, between an extended position in which a proximal end portion of the medicament delivery member sleeve extends proximally from the housing and a retracted position in which the proximal end portion is received by the housing, wherein the proximal end portion has a resilient structure, enabling compression of the proximal end portion in the distal direction upon impact of an axial force greater than a threshold value.

Abstract: The invention relates to an injection device for injecting a liquid drug. The injection device comprises a housing assembly supporting a non-removable cartridge having an interior chamber containing the liquid drug to be injected and a reusable needle cannula connected to the cartridge. A needle shield assembly provided with a cleaning chamber containing a volume of a cleaning agent for cleaning at least the distal tip of the needle cannula between subsequent injections is further provided.

Abstract: A system for injecting includes a cartridge body defining a proximal opening and a distal needle interface. The system also includes a plunger member defining a plunger interior and configured to be manually manipulated to insert a stopper member relative to the cartridge body. The plunger member includes a needle retention feature disposed in the plunger interior, an energy-storage member disposed in the plunger interior, and an energy-storage member latching member disposed in the plunger interior. The system further includes a needle hub assembly coupled to the distal needle interface of the cartridge body. The needle assembly includes a needle having a needle proximal end feature, a hub, and a needle latching member configured to couple the needle to the hub. The needle is retractable into plunger interior upon manipulation of the plunger member to actuate the energy-storage member latching member.

Abstract: A needle shield remover for assembly with a cap of a medicament delivery device, wherein the needle shield remover comprises a longitudinally elongated tubular body (10, 10?, 10?) having a plurality of structural features, wherein said plurality of structural features are symmetrically disposed on the tubular body (10, 10?, 10?), in relation to a plane of symmetry which is perpendicular to a longitudinal axis.

Abstract: Described is a medicament delivery device comprising a case adapted to hold a container with a medicament and having a needle, a needle sleeve telescopically coupled to the case and having a first extended position relative to the case in which the needle is covered, a retracted position relative to the case in which the needle is exposed, and a second extended position relative to the case in which the needle is covered, a first indicia disposed on the needle sleeve which is visible in the first extended position and the second extended position, and a second indicia disposed on the needle sleeve and not visible in the first extended position and visible the second extended position.

Abstract: Systems, devices, and methods for delivering an implant to the orbit. In some instances, the systems may include a delivery device having a tongue member and a handle. The delivery device may further include an ejector configured to deliver an implant from the tongue member. The delivery device may also include a piercing member configured to create an opening in tissue. The systems may further include a piercing member for creating an opening in tissue. In some instances, the piercing member may have a first blade member rotatably connected to a second blade member.

Abstract: Automatic injection device with trigger assembly. The trigger assembly includes a button (25), and a single prong (160) extending from a biased element of the device toward the button. A button-engaging surface (167) of the prong and a support surface of the device define a radially extending opening in which an actuating element (52) of the button fits for a radially outward face of the actuating element to be backed up by the support surface. For release of the biased element, when the button is pressed to shift the actuating element to cause a latching surface of the prong to disengage from a latch surface of the device, motion of the actuating element in a direction away from the prong is limited by the radially outward face of the actuating element abutting the support surface.

Abstract: A safety needle apparatus is provided. The safety needle apparatus includes a needle assembly including a needle mount and a needle cannula. The needle cannula defines a lumen and has a sharpened distal tip. The needle mount supports the proximal end of the needle cannula and is adapted to engage an intravenous line. The safety apparatus includes a shield positioned about the needle cannula. The needle cannula is movable in relation to the shield. The apparatus also includes a lock insert supported on the needle cannula and a locking member extending from an internal surface of the shield, wherein the locking insert and the locking member are configured to prevent movement of the needle cannula. A platform including a base member, which is configured to support the needle cannula at a substantially orthogonal orientation to the plane of a top surface of the platform and supports the shield, is included.

Abstract: An injection device that comprises a chamber configured for containing a substance to be injected and a needle operatively associated with the chamber and having a length sufficient to deliver the substance to an intradermal injection site. A collar surrounds the needle, defining a collar cavity. The collar also has a peripheral forward skin-contacting surface that surrounds and is radially spaced from the needle and injection site by an area that is sufficiently large to allow a patient's skin to move into the collar cavity to properly position the needle for intradermal delivery of the substance to the injection site to allow spread of the injected substance under the skin while inhibiting or preventing backpressure within the skin from forcing the substance out through the injection site.

Abstract: One embodiment is directed to a system for injecting, comprising a syringe body defining an interior medicine chamber; a stopper member configured to be inserted into the interior medicine chamber to contain medicine within the medicine chamber; a plunger member configured to be manually manipulated to insert the stopper member relative to the syringe body; a needle having proximal and distal ends, the proximal end comprising an anchoring geometry configured to be at least partially penetrated into the stopper member such that upon retraction of the stopper member, the needle is pulled proximally along with the stopper to be at least partially contained within the interior medicine chamber; and an energy-storing member operatively coupled between the stopper member and the syringe body, the energy-storing member configured to facilitate retraction of the stopper member relative to the syringe body.

Abstract: The invention relates to an injection device comprising a housing, a container holder arranged within said housing, the container holder being configured for accommodating a medicament container having a needle attached to one end thereof and a stopper sealingly and slidable arranged inside the medicament container at the other end thereof, a plunger rod being arranged with a proximal end thereof contactable with said stopper, a first and a second energy accumulating member arranged in the interior of the housing of the injection device and adapted to accumulate and store energy, plunger drive means being slidable arranged in relation to the plunger rod, being rotationally locked to the plunger rod and being rotatable in relation to the housing, the plunger drive means being operationally associated with the first energy accumulating member, a container driver arranged for being connectable to the container holder and threadedly connected to the plunger rod, the container driver being operationally associated

Abstract: An injector including a syringe arranged along a longitudinal axis, a removable cover for removable engagement with the syringe and a cover removal assembly including an outer portion which is engagable by a user and is movable axially in a cover disengagement direction along an axial travel path with respect to the longitudinal axis and an inner portion which includes at least one engagement portion which is engagable with the removable cover, whereby axial movement of the inner portion in the cover disengagement direction removes the removable cover from the syringe, at least one of the outer portion and the inner portion being configured such as to provide an axially floating lost motion engagement between the outer portion and the inner portion.

Abstract: According to the invention, an injection device (D) comprises a pre-filled syringe and a safety device. The pre-filled syringe comprises a barrel with an inner cavity in fluid communication with a hypodermic needle attached to a distal end of the pre-filled syringe and a piston fluid-tightly sealing a proximal end of the inner cavity. The safety device comprises a support body for retaining the pre-filled syringe therein, an outer body operably connected to the piston, a needle shield and a releasable retaining means (R). The retaining means comprises a radial projection and a longitudinal recess adapted to receive the radial projection. The radial projection is connected to or integral part of one of the support body or the outer body and a longitudinal recess formed into the other of the support body or the outer body. The needle shield, the support body and the outer body are telescopable relative to each other.

Abstract: In one embodiment of the invention, a container for storing a medicament prior to use is provided. The container includes a first housing for containing a medicament, a second housing, wherein the first housing is movable relative to the second housing, and an injection member associated with a lower portion of the first housing, wherein when the first housing moves relative to the second housing in a first direction to deliver the medicament, the injection member extends from the second housing traversing a first contaminant barrier disposed at a lower portion of the second housing. The first housing moves relative to the second housing in a second direction wherein the injection member is retracted into the second housing to prevent an unintentional contact with the injection member. In a further embodiment, an actuation mechanism for actuation of an injection includes a rotatable member.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament (M), comprising: an elongate outer casing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament (M), the outer casing having a distal end (D) and a proximal end (P) with an orifice intended to be applied against an injection site, wherein the syringe is slidably arranged with respect to the outer casing, spring means capable of, upon activation: pushing the needle past the proximal end (P), operating the syringe to supply the dose of medicament (M), and retracting the syringe with the needle activating means arranged to lock the spring means in a pressurized state prior to manual operation and capable of, upon manual operation, releasing the spring means for injection, wherein the spring means is a torsion spring grounded at one end in the outer casing and at the other end in a first gear member rotatable about a longitudinal axis, wherein the first g

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing, a syringe with needle and a stopper, a drive spring for pushing the needle from a covered position into an advanced position, for operating the syringe and for retracting the syringe, activating means for locking or releasing the spring means. A retraction sleeve is axially movable arranged in the housing. The drive spring bears with its proximal end against a thrust face of a decoupling member. At least one resilient decoupling arm is arranged at the decoupling member for bearing against a first shoulder of the plunger. At least one aperture is arranged in the retraction sleeve allowing the decoupling arms to be flexed outward thus allowing the first shoulder to slip past the decoupling arm.

Abstract: Drug delivery device, comprising a body unit having a first opening and a second opening, a plunger arranged such that its distal end is positioned inside the body unit, wherein the plunger is moveable in the distal direction with respect to the body unit, a needle assembly, with a proximal end and a distal end comprising a needle, wherein the proximal end of the needle assembly and the distal end of the plunger are configured such that they can get into an adhesion connection.

Abstract: The present invention safety device is a one-piece needle assembly that has a base and a housing pivotally connected to the base. The base has a distal portion to which a needle is fitted. At the base there is formed longitudinally along its distal portion a catch mechanism that may be in the form of an anchor projection. At the back wall of the housing there is extended another catch mechanism that may be configured in the form of two clasping fingers. Also providing in the housing is an integral hook. As the housing and the base are pivoted relative to each other, and as the needle makes contact with the hook, the respective catch mechanisms at the base and the housing also make contact with each other, resulting in the coupling of the catch mechanisms and the coupling of the needle to the hook. As a result, the catch mechanisms are interlocked and the needle is fixedly retained by the hook within the housing.

Abstract: A retractable syringe, plunger and releasable needle assembly including a retractable needle, a needle seal, a retaining member and an ejector member. The retaining member has a mating surface for mounting to a complementary mating surface of an interior wall of a syringe barrel. The plunger comprises a plunger outer, a plunger rod frangibly connected to a controlling member, a spring and a unitary plunger seal capable of engaging the retractable needle, wherein the plunger rod, plunger outer and the controlling member co-operate to releasably maintain the spring in an initially compressed state. After delivery of fluid contents of the syringe, the plunger forces the ejector member to release the retractable needle from the retaining member. Decompression of the spring at the end of depression of the plunger facilitates retraction of the retractable needle when engaged with the unitary plunger seal.

Abstract: The invention concerns an injection device for apportioning set doses of a drug from a reservoir to a subject. The injection device comprises a dose setting member (20, 70) which is screwed out from the housing (30) to set a dose and pushed axially back to the housing (30) in order to expel the set dose. A scale drum (80) is axially and inrotatable coupled to the dose setting member (20, 70) such that the scale drum (80) is rotated up a thread (34) when the dose setting member (20, 70) is rotated to set a dose. When the dose setting member (20, 70) is pushed axially back to its initial position to inject the set dose, the scale drum (80) is released from its inrotatable connection in order to allow the scale drum (80) to rotate down the thread (34) and back to its zero position.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament, comprising: an elongate housing arranged to contain a syringe with a hollow needle and a stopper for sealing the syringe and displacing the medicament, wherein the syringe is slidably arranged with respect to the housing, spring means capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end, operating the syringe to supply the dose of medicament, and retracting the syringe with the needle into the covered position after delivering the medicament, activating means. The spring means is a single drive spring arranged to be grounded at a distal end in the housing for advancing the needle and for injecting the dose of medicament via a plunger. The drive spring has its ground in the housing switched to its proximal end for retracting the syringe. An interlock sleeve is telescoped in the proximal end of the housing.

Abstract: An auto-injector for administering a dose of a liquid medicament (M) is presented having an elongate case arranged to be held by a user, a tubular chassis telescoped in the case and biased against the case so as to protrude from the case. The injector also includes a syringe with a hollow injection needle, a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe. A trigger button is distally arranged in or on the case, wherein the trigger button is initially coupled to the case in a manner to protrude distally from the case and interlocked to the chassis in a manner preventing the trigger button from disengaging the case.

Abstract: An injection device for use with a syringe having a syringe body, a needle coupled thereto, and a plunger moveable through the body to eject medication from the syringe through the needle, includes a housing defining an inner space for holding a syringe and facilitating movement thereof from a first position in which the needle is contained fully within the housing and a second position in which the needle projects from the housing, and a drive member located within the inner space so that in use the drive member can engage the plunger of a syringe held within the housing. The device further includes a force applicator located within the inner space for providing a force to the drive member so as to move the syringe from the first to the second position and thereafter to move the plunger through the syringe body, a trigger mechanism, and a damper.

Abstract: An auto-injector for administering a dose of a liquid medicament is presented that has a tubular chassis telescopable in a tubular case, a carrier subassembly comprising a tubular carrier slidably arranged relative to the chassis inside the case, where the carrier adapted to contain a syringe with a hollow injection needle. The injector has a drive spring and a plunger for forwarding load of the drive spring to a stopper of the syringe, wherein the syringe is lockable for joint axial translation with the carrier. There is also a trigger button arranged distally or laterally in or on the case, a control spring arranged around the carrier, and a needle extension control mechanism for coupling a proximal end of the control spring to either the carrier for advancing it for needle extension or to the chassis for needle retraction depending on the relative axial position of the carrier and the chassis.

Abstract: The invention relates to a detent mechanism for controlling translation between two components in a longitudinal direction (P, D), the detent mechanism comprising at least one clip on one of the components arranged to be in a ramped engagement with a recess in the other one of the components in an initial state in such a manner that translation between the components is constrained and that application of a translative force between the components in one longitudinal direction (P, D) with the clip engaged with the recess deflects the clip out of the recess when a predetermined value of the translative force, at least depending on the resilience of the clip, is overcome so as to allow translation between the components.

Abstract: A syringe which disperses medicate across a zone in the body during apparent conventional operation. The improved syringe includes a barrel, a plunger, and an operating cylinder. In operation, the needle of the syringe is inserted into the body at the distal portion of the portion of the body which is to receive the medicate. A single arm is attached to the barrel and passes through an operating cylinder with a thumb rest on its top. As a result, in operation, the user draws the single arm up to the thumb rest, thus causing the syringe to withdraw during injection and leaving a patch of medicate during operation.

Abstract: An aspiration tube has a relatively high fluidic resistance. The tube is coupled to a medical device and a pump of an aspiration system. The tube can be designed to create a pressure drop that at least equals the maximum vacuum pressure of the pump. The fluidic resistance can be accomplished with a tube having an inner diameter less than 0.05 inches. The aspiration tube and an irrigation tube may be coupled to an anterior chamber of a cornea during a phaco procedure. The aspiration tube is sized so that even if a maximum pressure occurs, the resultant aspiration flowrate will be such that the cornea will not be damaged when an occlusion is cleared from the tube. An in-line filter may also be attached to the aspiration tube to filter out particles in the system.

Abstract: The invention relates to an auto-injector for administering a dose of a liquid medicament (M), comprising: an elongate housing arranged to contain a syringe, the housing having a distal end (D) and a proximal end (P) with an orifice, wherein the syringe is slidably arranged with respect to the housing, a drive spring capable of, upon activation: pushing the needle from a covered position inside the housing into an advanced position through the orifice and past the proximal end (P), and operating the syringe to supply the dose of medicament (M), and activating means arranged to lock the drive spring in a compressed state and capable of releasing the drive spring for injection, wherein the elongate housing comprises a distal portion and a proximal portion connected by a hinge, the portions rotatable about the hinge between an aligned position and a maximum opening angle, wherein the drive spring may be compressed by rotating the portions towards the maximum opening angle, wherein the activating means are arrang

Abstract: A cannulation system for perfusing a patient's circulatory system, includes an inflow cannula having a first end adapted to be connected to said circulatory system and a second end adapted to be connected to a blood pump, an outflow cannula having a first end adapted to be connected to the blood pump and a second end adapted to be connected to said circulatory system at a location downstream of the first end of the inflow cannula. The flow of blood from the pump is in series with the normal blood flow of the circulatory system of the patient and creates a localized region of hypertension.

Abstract: A syringe (1) comprises a barrel (2) for containing a substance to be injected, a needle carrier (12) for carrying a needle (10), and a plunger (3) which is adapted to be movable in the barrel 2 to expel the substance to be injected from the needle (10). The plunger (3) has a first part (3a), a second part (3b) and a resilient member (6) therebetween, the first (3a) and second (3b) parts being adapted to be releasably locked together to hold the resilient member (6) in a compressed state. In use, the first part 3a of the plunger (3) and the needle carrier (12) are adapted to engage one another following expulsion of the substance, and the second part (3b) of the plunger (3) is adapted to be unlocked from the first part (3a) following said engagement, allowing the resilient member (6) to expand to propel the needle carrier (12) into the barrel (2).

Abstract: A system for perfusion management that monitors, maintains, diagnoses, or treats perfusion deficiencies.

Abstract: A system for perfusion management that monitors, maintains, diagnoses, or treats perfusion deficiencies.

Abstract: A system for perfusion management that monitors, maintains, diagnoses, or treats perfusion deficiencies.

Abstract: An apparatus includes a housing, a medicament container and a movable member. The medicament container is configured to move within the housing between a first position and a second position in response to a force produced by an energy storage member. A proximal end portion of the medicament container includes a flange and has a plunger disposed therein. A first shoulder of the movable member is configured to exert the force on the flange to move the medicament container from the first position to the second position. A portion of the first shoulder deforms when the medicament container is in the second position such that at least a portion of the force is exerted upon the plunger. A second shoulder of the movable member is configured to exert a retraction force on the flange to move the medicament container from the second position towards the first position.

Abstract: A safety carpule system with integral retractable needle includes a piston element disposed between a needle hub assembly and a plunger element, each being axially slideable within a cylindrical housing. A medication-filled fluid chamber is defined between the plunger element and the piston element. The piston element is forced to into a fluid release position by way of an increase in fluid pressure within the fluid chamber, which in turn is caused by actuation of the plunger element toward the needle hub assembly by way of a syringe plunger rod. When the piston element is in fluid release position, the medication is able to flow from the fluid chamber through the needle as the syringe plunger rod is further compressed. Once the carpule system is spent, the piston element is latchably engaged by both the needle hub assembly and the plunger element, thus allowing the needle to be fully retracted into the housing upon return of the syringe plunger rod to its extended position.

Abstract: An injection device comprises a syringe extendible against a spring bias from a retracted position in a housing to a projecting injecting position. A spring biased plunger has collapsible elbows which, when the plunger is released, initially engage the end of the syringe to drive it to the projecting position, whereupon arresting of the syringe movement causes the elbows to collapse inside the syringe to allow the plunger to engage and drive the bung.

Abstract: An injection device comprising an outer housing adapted to receive a syringe for holding a volume of a medicament, said syringe comprising a barrel, a needle at one end of the barrel, and a plunger, axially moveable within the barrel, the needle and barrel being such that at least part of the needle is axially moveable in and out of said outer housing but is biased to be normally wholly inside said housing. The injection device further comprises an inner housing intermediate the outer housing and at least part of the barrel and/or plunger, an energy source in communication with the inner housing, and blocking means capable of preventing said inner housing moving axially under the influence of said energy source.

Abstract: A retractable safety syringe may have a ferrule and needle which are selectively removeable from a distal end of a syringe body. In particular, the ferrule may have an annular flange. A wedge element may be frictionally engaged to the ferrule and a distal end of the syringe body. To retract the needle into the syringe body, a punch of a piston displaces the wedge element off of an annular flange of the ferrule. At about the same time, longitudinally offset tabs engage an annular flange and retract the needle into the syringe body via a retraction force created by a variable vacuum compartment or tension member. Alternatively, the ferrule and needle may be temporarily fixed to the distal end of the syringe body via a detent and/or o-ring which engages a lower undercut groove and an upper undercut groove of the ferrule. An annular ring of the piston may have longitudinal offset tabs which engage an annular ring of the ferrule.

Abstract: A retractable syringe (30) comprising a hollow barrel (32) with a radially inwardly facing abutment surface (54) and a needle hub (40) having first engagement formation (42) integrally formed with the needle hub. A radially outer portion (50) of the first engagement formation (42) is engaged with the abutment surface (54) to radially inwardly bias the first engagement formation (42). A plunger includes a second engagement formation (60) which the first engagement formation captively engages at the end of a stroke thereby engaging the plunger (34) with the needle hub (40). The needle tip is retractable into the barrel (34) upon application of a predetermined longitudinal force to the plunger (34).

Abstract: The present invention provides for an injection device including a syringe with a proximal end, a distal end, a needle extending from the distal end, and a plunger inserted into the proximal end. A guard is slidable on the syringe, has a proximal end, a distal end, and is biased from a first position wherein the needle is exposed towards a second position wherein the guard covers the needle. The injection device includes first and second sets of cooperating detents for retaining the guard and syringe in the first and second positions, respectively. A latch member extends proximally from the guard that is engageable by the plunger as the plunger is depressed to release the first set of cooperating detents. Upon release, a spring element biases the guard towards the second position until the second set of cooperating detents engage and secure the guard in the second position.

Abstract: The present invention provides a needle-retractable safety including an improved barrel type plunger, including a barrel, a needle retracted trigger and a supporting member. A front portion of the barrel is fitted over a sealing rubber pad, a slotted hole is disposed at a wall of the front portion of the barrel, a bearing piece is provided in the slotted hole, and one end of the bearing piece is connected to the front side wall of the slotted hole. The barrel and supporting member are provided with a snap-in structure, respectively, which make supporting member releasably engaged in said barrel. The supporting member is able to translate backwards under the action of a needle retraction force so that said bearing piece can be returned to such a position that said needle can be retracted backwards to the interior of the barrel.

Abstract: A retractable safety syringe may have a ferrule and needle which are selectively removeable from a distal end of a syringe body. In particular, the ferrule may have an annular flange. A wedge element may be frictionally engaged to the ferrule and a distal end of the syringe body. To retract the needle into the syringe body, a punch of a piston displaces the wedge element off of an annular flange of the ferrule. At about the same time, longitudinally offset tabs engage an annular flange and retract the needle into the syringe body via a retraction force created by a variable vacuum compartment or tension member. Alternatively, the ferrule and needle may be temporarily fixed to the distal end of the syringe body via a detent and/or o-ring which engages a lower undercut groove and an upper undercut groove of the ferrule. An annular ring of the piston may have longitudinal offset tabs which engage an annular ring of the ferrule.

Abstract: A cannulation system (10) for perfusing a patient's circulatory system, includes an inflow cannula (14) having a first end adapted to be connected to said circulatory system and a second end adapted to be connected to a blood pump (19), an outflow cannula (23) having a first end adapted to be connected to the blood pump (19) and a second end adapted to be connected to said circulatory system at a location downstream of the first end of the inflow cannula. The flow of blood from the pump (19) is in series with the normal blood flow of the circulatory system of the patient and creates a localized region of hypertension.

Abstract: Syringe assemblies are described with at least two co-axially positioned cylinders that move relative to one another by action of a spring. Aspects of the syringe assemblies include a protective unit in which a first cylinder of a first length is attached to a second cylinder of shorter second length. In different embodiments, a protective unit is formed of a single or singularly fabricated cylinder. The different protective units may be used with a syringe in which action of a plunger to push a plunger tip into contact with a distal wall of the syringe cylinder to discharge fluid located inside the syringe but does not immediately release the protective unit relative to the syringe cylinder to shield a needle.