Abstract: A needle shield remover for removing a needle shield from a syringe. The needle shield remover comprises a receiving means to receive at least part of the needle shield, removing means to detach the needle shield from the syringe whilst it is present in the receiving means; and retaining means to temporarily retain the needle shield in the receiving means after removal of the syringe. Temporarily retaining the needle shield in the needle shield remover allows the needle shield remover to be reused. Additionally, by retaining the needle shield the needle shield remover prevents the needle shield from being lost or dropped on the floor when it is not retained within the needle shield.

Abstract: Systems and methods are described for monitoring usage of a medicament dispenser—particularly an inhaled medicament dispenser. The usage monitoring device is configured to emit a detection signal responsive to receiving a request to locate the medicament dispenser. The detection signal alerts presence of the medicament dispenser to the user of the medicament dispenser. The usage monitoring device can be embodied as an attachment configured to be selectively coupled to one of a variety of different inhalers including, for example, a Diskus-type inhaler and a Respimat-type inhaler.

Abstract: An urethral antimicrobial delivery device (1) comprising; a deformable reservoir (101) in fluid connection with an elongate member (102), the elongate member comprising a lumen, the elongate member having a proximal end and a distal end, the elongate member having a plurality of pores (103) defined therein, said pores being distributed along a length of said elongate member, the elongate member being dimensioned for insertion through an external urethral orifice of a female subject, whereby the elongate member is insertable into a distal urethral cavity for delivery of an antimicrobial in said distal urethral cavity, and wherein the device comprises a collar (105) to prevent said elongate member entering a proximal urethral cavity.

Abstract: A drug delivery device configured to provide a dose of a first medicament followed by a dose of a second medicament is disclosed. The device includes a main exterior body and an interior body. The device further includes a dual-chamber reservoir with (i) a first chamber holding the first medicament and (ii) a second chamber holding the second medicament. The device also includes a needle and a plunger. After activation of the device, the plunger is configured to (i) move the dual-chamber reservoir a given distance in a distal direction with respect to the interior body so that a distal end of the needle extends out of the interior body and (ii) after moving the dual-chamber reservoir the given distance, move in the distal direction with respect to the dual-chamber reservoir so as to eject from the needle the first medicament followed by the second medicament.

Abstract: A syringe having barrel defining an outer circumferential surface, and a distal end including a non-luer tip that is not connectable to an intravenous device. The syringe barrel defines a snap-in, syringe engagement feature, adjacent to its distal end, oriented on its outer circumferential surface, which is selectively insertable within a bore of a complementary enteral collar. A proximal end of the enteral collar has a snap-in, enteral collar engagement feature, in the bore of the collar. In some embodiments, the snap-in, enteral collar engagement feature includes one or more cantilever snap joints, which engage a recess in the syringe engagement feature, upon axial insertion of the syringe tip into the bore of the collar. In some embodiments, the enteral collar engagement feature includes a discontinuous-annular snap joint. The enteral collar is sized to permit connection to an enteral device and prevent connection to a device having a luer connector.

Abstract: An endoscope having a proximal end and a distal end, a handle at the proximal end and an insertion tube extending from the proximal end towards the distal end. The insertion tube includes an internal working channel extending from the handle to the distal end of the insertion tube. A connector at the handle is adapted for the attachment of a syringe. A recess is adapted to accommodate a cylindrical body of the syringe when said syringe is attached to the connector.

Abstract: A medicament container holder for a medicament delivery device is presented having a C-shaped tubular body having a longitudinal gap extending along the entire axial extension of the C-shaped tubular body, which C-shaped tubular body is configured to be placed around a medicament container, wherein the C-shaped tubular body has a first axial end provided with an end flange extending radially inwards and configured to bear against a neck of a medicament container, and wherein the first axial end is provided with a lip extending proximally from the end flange.

Abstract: A reporting syringe, including a barrel in fluid communication with a needle connected with a first end of the barrel, a piston including a plunger, the piston positioned within a second end of the barrel and the plunger having a fluid-tight interaction with an interior of the barrel, and a microprocessor in electronic communication with a switch and a wireless module, the microprocessor configured to send an administration completion data from the wireless module after triggering the switch.

Abstract: A method of inhibiting neuroinflammation in neuron surrounding cells, includes a step of treating the neuron surrounding cells with at least one tyrosine kinase inhibitor or sirtuin-2 inhibitor or a combination thereof, to inhibit the neuroinflammation. A method of managing neuroinflammation or neuroinflammation mediated neurodegenerative disease or disorder in a subject in need thereof, includes administering at least one tyrosine kinase inhibitor or sirtuin-2 inhibitor or a combination thereof to the subject. A composition includes at least one tyrosine kinase inhibitor or at least one sirtuin-2 inhibitor optionally along with pharmaceutically acceptable excipient.

Abstract: One embodiment is directed to a safety syringe system, comprising: an off-the-shelf syringe assembly comprising a syringe body and a plunger tip; a needle assembly removably coupleable to the distal end of the syringe body such that medicinal fluid may be transferred through a retractable needle coupled to a needle housing comprising the needle assembly upon insertion of the plunger tip relative to the syringe body; and a plunger control assembly coupled to the plunger tip and configured to facilitate manual insertion of the plunger tip relative to the syringe body; wherein upon insertion of the plunger tip to a final insertion state and release of an associated manual insertion load, the plunger tip may be proximally withdrawn, pulling the retractable needle proximally relative to the needle housing to a safe locked and retracted state wherein it is no longer exposed for injection.

Abstract: Medical devices and methods of treating subjects using such medical devices are described. The medical device may include a housing with at least two chambers including a first chamber adjacent to a second chamber; a barrier between the first chamber and the second chamber; and a soft, flexible base. The first and second chambers may be airtight, the barrier configured to establish fluid communication between the first chamber and the second chamber upon an application of force to the barrier.

Abstract: Delivery systems and methods for forming and delivering biomaterials from two components are described herein. In particular, apparatus and methods for performing controlled delivery of multicomponent delivery of biomaterials into or onto a body part, such as a body lumen are described. More specifically, in some embodiments, the apparatus and methods are directed towards controlled delivery of micro-volumes of biomaterials into or onto a target location, the micro-volumes being defined as 0.001 mL-1 mL (or 1 ?L-1,000 ?L) of volume.

Abstract: A needle-equipped outer tube includes a needle; a joint member that supports the needle, the needle being insert molded or thermally welded to the joint member; and an outer tube including a connection section, wherein the joint member is thermally welded to the connection section of the outer tube.

Abstract: A medical injector includes an injector housing defining a reservoir, a plunger rod, and a stopper engaged with a portion of the plunger rod, the stopper being slidably disposed within the reservoir and sized relative to an interior of the injector housing to provide sealing engagement with a sidewall of the injector housing. The medical injector further includes a needle having a sharpened first end and a second end in communication with the reservoir, a first cap covering the sharpened first end of the needle, and a second cap covering at least a part of the first cap. The second cap includes a body having a proximal end, a distal end, and a hemispherical member including a gripping component. The second cap is engaged with the first cap such that removal of the second cap simultaneously removes the first cap from the first end of the needle.

Abstract: A connector assembly may include a body and a fluid fitting, the fluid fitting configured for releasably engaging a syringe nozzle, at least one deflectable locking arm connected to the body and radially deflectable relative to the distal end, the proximal end of the at least one deflectable locking arm configured for deflecting in a radial direction relative to the distal end to releasably engage the syringe nozzle, and at least one locking element disposed on the at least one deflectable locking arm, the at least one locking element movable with movement of the at least one deflectable locking arm between a first position where the at least one locking element is released from an engagement portion of the syringe nozzle and a second position where the at least one locking element is engaged with the engagement portion of the syringe nozzle.

Abstract: A blinding cap for covering a rigid needle shield that is covering a needle of a syringe includes an elongated body extending between a proximal end and an opposing distal end, the body at least partially bounding a chamber. An annular sleeve projects from the proximal end of the body and at least partially bounds a channel. A first flange radially inwardly projects from the body into the chamber, the first flange at least partially bounding an opening that provides communication between the chamber and the channel.

Abstract: The disclosed embodiments related to an apparatus and methods for biological sample processing enabling isolation and concentration of microbial or pathogenic constituents from the sample. Sample may be obtained directly from a specimen container, such as a vacutainer, and processed directly without risk of user exposure. The disclosed methods and apparatus provide a convenient and inexpensive solution for rapid sample preparation compatible with downstream analysis techniques.

Abstract: A syringe body for a prefilled syringe includes: a hollow body portion; a proximal-end opening portion provided at a proximal end portion of the body portion; and a distal-end nozzle provided at a distal end portion of the body portion. The body portion is made of a cyclic olefin polymer or a cyclic olefin copolymer. The body portion has a thick body portion accounting for 80% or more of the body portion along an axial direction. A wall thickness of the thick body portion is 2.23 to 2.40 mm.

Abstract: The invention relates to a method for producing a syringe having a piercing means, comprising the following steps: a) providing a syringe body having a distal end section, which comprises an inner channel that discharges at a distal opening, wherein the distal end section is in a formable state; b) providing a piercing means; c) inserting a proximal section of the piercing means through the distal opening into the inner channel of the distal end section; and d) shaping the distal end section by means of a first shaping tool in such a way that an inner surface of the distal end section contacts at least portions of the piercing means, as a result of which at least portions of the piercing means are secured.

Abstract: Provided are methods for surface-modifying a rubber vulcanizate and surface-modified elastic bodies, which can cost-effectively provide a variety of functions, including sliding properties, liquid leakage resistance, and protein adsorption resistance. Included is a method for surface-modifying a rubber vulcanizate as a modification target, the method including: step 1 of forming polymerization initiation points A on the surface of the modification target; step 2 of radically polymerizing a monomer starting from the polymerization initiation points A to grow polymer chains; and step 3 of adding a silane compound to the surfaces of the polymer chains, followed by reaction with at least a fluoroalkyl group-containing silane compound to form modified polymer chains.

Abstract: A medication injection pen comprises a dose set knob rotatable with respect to a housing to set a desired injection dose. The dose set knob comprises at least one internal thread. A leadscrew includes a thread element for advancing in a first direction via a corresponding thread engagement. A driver is rotationally fixed to the leadscrew and is rotatable in a first direction to rotate and advance the leadscrew in the first direction. The setback member is rotationally fixed to the driver. The dose stop member is rotationally coupled to the setback member and is axially movable relative to the dose set knob when the dose set knob is rotated relative to the setback member. Axial movement of the dose stop member limits the user from setting a dose that is greater than an injectable volume of medication remaining in a cartridge.

Abstract: The present disclosure relates to a cartridge holder of an injection device, the cartridge holder comprising a tubular shaped elongated sleeve extending in an axial direction to accommodate a cartridge filled with a medicament, wherein the sleeve (29) comprises: a proximal connecting end to connect with a distal connecting end of a body of the injection device, which body is configured to accommodate a drive mechanism of the injection device and which drive mechanism is operably engageable with a piston of the cartridge, a flange section extending radially outwardly from an outside surface of the sleeve and having a proximally facing abutment face to axially abut with a distal end face of the distal connecting end of the body, at least three protrusions located distally from the flange section, extending radially outwardly from the outside surface of the sleeve and being distributed around the circumference of the sleeve.

Abstract: The present disclosure is generally directed to a drive mechanism for use in a drug delivery device having a cylindrical cartridge, i.e. a handheld injection device for selecting and dispensing a number of user variable doses of a medicament. The drive mechanism includes a base element, a toothed piston rod, which is guided within and movable relative to the base element, and a drive gear having a pinion, which is rotatably held in the base element and in meshed engagement with the toothed piston rod. The toothed piston rod includes multiple rigid rod pieces which are connected by hinges. The rigid rod pieces comprise a flat plate provided with a straight toothed rack.

Abstract: Devices and methods for collecting trace amounts of samples are provided. A device can utilize a sterile syringe integrated with a venturi-type vacuum source for sample collection. The device can be used in a variety of applications for collecting specimens that are otherwise difficult to retrieve using conventional sample collecting techniques.

Abstract: A fluid dispensing device is provided for dispensing a measured amount of fluid into a living organism. The device includes a rigid fluid reservoir closed by a septum for use in a fluid dispensing device for dispensing a measured amount of fluid into a living organism, wherein the device has a main housing enclosing the operative components of the device, the said fluid reservoir located within the main housing, an injection assembly including a needle, and a trigger mechanism. The needle has a first end adapted to piercing the septum and pushing the septum into the reservoir so that the septum acts as a piston, expelling the fluid through the needle, and a second end adapted to injecting the fluid into the living organism.

Abstract: The present application relates to an intermediate structure for a support structure of a medicament delivery device, which support structure is to cooperate with a medicament container, said support structure comprising a flexible element arranged to exert a force on a distal end surface of said medicament container, wherein said intermediate structure is arranged between said flexible element and said end surface and arranged to guide said flexible element in an outwardly direction in relation to a longitudinal axis (L) when exerting a force on said medicament container.

Abstract: Described is a medicament delivery device (1) comprising a body (2), a container carrier (7) slidably disposed in the body (2), and a sleeve (6) slidably coupled to the container carrier (7).

Abstract: The disclosure relates to a medicament delivery device, comprising: a tubular body having a distal end, a cap adapted to be connected to the distal end (of the body, wherein the body comprises a first clip having a first stop and a first ramp, wherein the cap comprises a second clip having a second stop and a second ramp, wherein the first ramp and the second ramp are adapted to be mutually engaged when the cap is connected to the body in a first position, wherein the first ramp and the second ramp are adapted to resiliently deflect at least one of the first clip and the second clip when the cap is being moved from the first position towards a second position, wherein in the second position the first stop and the second stop abut each other to prevent the cap from being moved into the first position. Furthermore, the disclosure relates to a method for assembling the medicament delivery device.

Abstract: The disclosure relates to a medicament delivery device, comprising: a tubular body having a distal end, a cap adapted to be connected to the distal end (of the body, wherein the body comprises a first clip having a first stop and a first ramp, wherein the cap comprises a second clip having a second stop and a second ramp, wherein the first ramp and the second ramp are adapted to be mutually engaged when the cap is connected to the body in a first position, wherein the first ramp and the second ramp are adapted to resiliently deflect at least one of the first clip and the second clip when the cap is being moved from the first position towards a second position, wherein in the second position the first stop and the second stop abut each other to prevent the cap from being moved into the first position. Furthermore, the disclosure relates to a method for assembling the medicament delivery device.

Abstract: A system for treating regurgitation of blood through a diseased heart valve having at least two leaflets can include an implantable, lollipop-shaped device and an adjustment mechanism. The device can have a proximal end portion, a distal end portion, and an intermediate portion extending therebetween. The intermediate portion can include an expandable occluding member having a selectively adjustable diameter and a biocompatible layer attached to at least a portion thereof. The distal end portion can include an anchoring member. The adjustment member can include a distal connecting end that is operatively connected to the proximal end portion of the device. Operation of the adjustment member, after implantation of the device, can cause the diameter of the occluding member to change so that at least one of the heart leaflet coapts with a portion of the occluding member to mitigate or prevent regurgitation of blood through the diseased heart valve.

Abstract: An apparatus for insertion of a medical device in the skin of a subject is provided.

Abstract: Various embodiments of the present invention are directed to transferring fluidic media from a vial to a reservoir. In various embodiments, fluidic media may be transferred from the vial to the reservoir by moving a housing portion to move a plunger head located in the reservoir to draw fluidic media from the vial to the reservoir. In other embodiments, fluidic media may be transferred from the vial to the reservoir while the reservoir is held by a holding unit and vibrated by a vibrator to remove air from the fluidic media. In some embodiments, fluidic media may be transferred from the vial to the reservoir by moving a handle operatively connected to a bias member for assisting with the transfer of fluidic media. In other embodiments, the transfer of fluidic media may be assisted by a bias member and a needle connecting atmosphere and the vial.

Abstract: Disclosed are plunger assemblies including various convertible plungers and methods of making the same. Each plunger assembly is configured for disposition within a barrel of a medical container, e.g., a syringe, and displaced within the barrel from an engagement position to a release position. The engagement position is configured to provide a compression seal between a storage sealing section of the plunger and an inner wall of the syringe barrel. In the release position, the compression seal is reduced or eliminated. Also disclosed are methods for making convertible plungers and as assembling them into syringes, e.g., pre-filled syringes.

Abstract: The housing for mounting an elongate-shaped container on an injection pen comprises an elongate-shaped body which extends along a longitudinal axis (X30) and which defines an interior volume (V32) for fully receiving the container. The body is provided, on the outside of a first axial end, with at least one first mechanical member for attaching a needle. The body is further provided, in the vicinity of a second axial end opposite the first axial end, with at least one second mechanical member for attaching the housing onto an injection pen. The housing further comprises, in the vicinity of the first axial end thereof, at least one third mechanical member for irreversibly locking a container in position, fully contained in the interior volume (V32) of the body of the housing. Said third locking member is formed by an elastically deformable tab intended to ensure locking of the container in position in the interior volume (V32) of the body of the housing, by axially retaining a flange of the container.

Abstract: An auto-injector for delivering a liquid medicament includes a housing arranged to contain a syringe with a piston for sealing the syringe and displacing the medicament, the housing having a proximal end and a distal end and a telescopic plunger unit arranged between the piston and the proximal end of the housing, the telescopic plunger unit comprising a telescopic frame and a spring element surrounding a plunger element. The plunger element is fixed to a base of the telescopic plunger unit and the spring element is held in an initial compressed state by a compressive force exerted by the base of the telescopic plunger unit. When the spring element is released, a tapering profile of the telescopic frame is configured to provide varying friction with extension such that resistance to telescopic extension decreases as spring force provided by the spring element decreases with increasing extension of the telescopic plunger unit.

Abstract: A drug delivery device comprising: a housing; a cylindrical member rotatably supported within the housing; and a plurality of sensors; wherein: the outer surface of the cylindrical member is provided with a single track, the track forming an encoder and having a plurality of first track segments and a plurality of second track segments arranged along the length of the track which are respectively capable of inducing first and second responses in the sensors; and in each rotational position of the cylindrical member relative to the housing at least one different first track segment is capable of inducing a first response in at least one said sensor, thereby enabling the rotational position of the cylindrical member relative to the housing to be determined.

Abstract: The invention relates to a carpoule holder (8) for receiving a carpoule (10) and for fastening to a drive mechanism and/or to a dosing mechanism and/or to a housing (6) of an injection device, with a holding element (9, 9?, 9?) for fastening the carpoule (10) to or in the carpoule holder (8), wherein the holding element (9, 9?, 9?) is designed in such a way that it can be connected to the carpoule holder (8) and can be received completely by the carpoule holder (8).

Abstract: A prefilled syringe includes a syringe barrel including: a liquid drug discharge portion on a distal end of the barrel, and an opening on a proximal end of the barrel; a cap; a gasket located in the syringe barrel; a plunger including: a shaft portion inserted in the syringe barrel from the opening, and a pressing portion located on a proximal end of the shaft portion and configured to be manually pushed by a user, the plunger being movable toward a distal direction by pushing the pressing portion to slide the gasket toward the liquid drug discharge portion; a liquid drug; an upraised portion located on an inner wall of the syringe barrel between the gasket and the opening; and a clicker.

Abstract: The present disclosure relates to a magnifying device attachable to an injection device. The magnifying device includes a frame having a distal end and having a proximal end opposite to the distal end and further has a receptacle extending from the distal end towards the proximal end. The receptacle is accessible from the distal end to receive a proximal end section of the injection device therein. A magnifying lens is fixed to the proximal end of the frame and extending at least partially across the proximal end of the frame.

Abstract: The present disclosure relates to a medicament delivery device comprising: a housing (3), a plunger rod received by the housing (3), which plunger rod is rotatable in a first direction relative to the housing (3) and linearly displaceable, an activation button arrangement linearly displaceable from a first position to a second position to thereby rotate the plunger rod in the first direction, a second direction rotation preventer having an annular outer member that is rotationally fixed relative to the housing (3) and an annular inner member partially received by the outer member, wherein the outer member and the inner member are arranged to receive the plunger rod and wherein the inner member is rotationally interlocked with the plunger rod, wherein the outer member and the inner member are structured to allow the inner member to rotate in the first direction relative to the outer member and to prevent the inner member from rotating in a second direction opposite to the first direction, and a recording unit

Abstract: A sensor device (2) is removably attachable to a drug delivery device (12). The sensor device comprises an array (20) of optical sensors arranged within the sensor device such that, when the sensor device is attached to the drug delivery device, the drug delivery device having a first movable element (14) which is configured to move along a path parallel to the longitudinal axis of the drug delivery device, each optical sensor is operable to detect light received at different locations along the linear path and to output a signal indicative of an amount of detected light; and circuitry (21) configured to receive the signals output from the optical sensors and, based on the received signals, to determine information associated with a location along the path of the first movable element.

Abstract: A drive and dosing device is described for an injection device for administering a fluid product, in particular a medication, wherein the drive and dosing device can be adjusted to a product dose to be administered. The drive and dosing device has, among other things, a coupling which, upon activation of an activation element, enables rotation of a rotation element relative to a housing, wherein by disengaging the activation element, the rotation of the rotation element relative to the housing is blocked.

Abstract: Methods and systems for a cartridge assembly for use with an injection system are provided. An example cartridge assembly may include an ampule containing a pharmaceutical product that is sealed at a distal end with a pierceable diaphragm. The cartridge assembly may also include a hub comprising a proximal portion defining a cavity that is configured to engage the distal end of the ampule and a piercing member positioned within the cavity. The piercing member may include a fluid pathway between a proximal end portion comprising an opening and a distal end in fluid communication with a distal opening of the hub. The proximal end portion may engage the pierceable diaphragm, and the piercing member may apply a force to the pierceable diaphragm in the inactivated position without penetrating the pierceable diaphragm.

Abstract: Provided is a system and method for a flared luer connector for medical tubing. More specifically, the flared luer connector includes a tube head adapter formed of a resilient material providing an inlet and opposite thereto an outlet with a longitudinal axis there between. A luer lock fitting is formed proximate to the inlet and structured and arranged to engage a syringe, and at least one flared member disposed between the luer lock fitting and the outlet, the flared member rising from the tube head adapter and angled towards the outlet. The flared member also provides at least one engaging surface between the tube head adapter and a distal edge, the engaging surface acutely angled with respect to the longitudinal axis. The engaging surface is structured and arranged to engage with a corresponding receiving section of a base, the base having a deflector section structured and arranged to deflect a tube head adapter having other than the corresponding flared member.

Abstract: A system for filling a fluid reservoir of a fluid infusion device with a fluid is provided. The system includes the fluid reservoir having a first portion and a second portion. A fluid chamber is defined between the first portion and the second portion. The second portion is movable within the first portion and includes an interface. The system includes a transfer guard having a first end and a second end. The first end to be coupled to a source of the fluid and the second end having at least one locking member that couples to the interface. The transfer guard defines a fluid flow path for the fluid from the source, and the transfer guard is movable relative to the first portion to fill the fluid chamber with the fluid.

Abstract: A biopsy device holder includes a needle holder, a distal holder, and a proximal holder. The needle holder includes an elongated housing extending between an open proximal end and a distal end. The needle holder is adapted to releasably receive the biopsy device through the open proximal end. The elongated housing includes a coupler configured to couple the needle holder to the biopsy device. The distal holder includes an opening configured to pivotably receive the distal end of the needle holder. The proximal holder includes a longitudinal stop that engages with a portion of the needle holder to prevent the needle holder from proximal longitudinal movement. The longitudinal stop is configured to disengage the coupler of the needle holder from the biopsy device when the biopsy device is moved proximally in a longitudinal direction.

Abstract: A device (2) for continuous infusions has a housing (4) in which an infusion appliance seat (6) is provided for receiving an infusion appliance (18) with at least one container (22) that can be pressed empty by means of a ram (20), which infusion appliance seat (6) extends along a main axis of extent (AA) from a ram-side end (26) to an outlet-side end (28). The continuous infusion device (2) moreover has an actuator (30) for automatically emptying the infusion appliance (18), a drive (32) for moving a ram abutment/actuation element (24) of the actuator (30), and a control arrangement (72) by means of which a speed of advance of the actuator (30) is adjustable. Provision is made here that the main axis of extent (AA) of the infusion appliance seat (6) has a predetermined relief angle (W) in relation to a support plane (E) of the housing (4), and here the outlet-side end (28) is arranged above the ram-side end (26) of the infusion appliance seat (6).

Abstract: Provided is a system and method for a removable syringe micro pump. More specifically, the removable syringe micro pump includes a pump housing having a first end and opposite thereto an attaching end, and at least one sidewall there between, the housing having a base proximate to the first end and, the attaching end having an attacher structured and arranged to temporarily engage a syringe. A volute spring is nested within the housing and attached proximate to the base, the volute spring having a compressed first position wherein coils of the volute spring are concentrically disposed under tension such that an initial height of the volute spring is equivalent to a width of a coil, and an extended second position wherein the release of tension extends the volute spring normally away from the pump housing. The volute spring has a diameter pre-selected to pass within a barrel of the engaged syringe.

Abstract: The surgical robotic access system provides access for robotic instruments and/or actuators including the introduction, operation and withdrawal of such robotic manipulators into a body cavity without permitting the escape of pressurized fluid or gas. The surgical robotic access system also provides a multi-faceted range of movement without touching or effecting pressure on the opening in the patient's body cavity.

Abstract: An exemplary embodiment of an injector includes a trigger mechanism, an energy source, and a user-operable firing-initiation member. The trigger mechanism can include a floating trigger member having a retaining portion, a ram assembly having a ram configured to pressurize a medicament container for expelling a medicament therefrom, the ram assembly further having a floating trigger engagement member configured to engage the retaining portion of the floating trigger member when the floating trigger member is in a pre-firing condition. The energy source can be associated with the ram for powering the ram to expel the medicament, and the user-operable firing-initiation member can be operable for causing an axial rotation of the floating trigger member from the pre-firing condition to a firing condition in which the floating trigger engagement member is released from the retaining portion to allow the energy source to fire the ram.