Abstract: A wound treatment appliance is provided for treating all or a portion of a wound. In some embodiments, the appliance comprises an impermeable flexible overlay that covers all or a portion of the wound for purposes of applying a reduced pressure to the covered portion of the wound. In other embodiments, the impermeable flexible overlay comprises suction assistance means, such as channels, which assist in the application of reduced pressure to the area of the wound and removal of exudate from the wound. In other embodiments, the wound treatment appliance also includes a vacuum system to supply reduced pressure to the wound in the area under the flexible overlay. In yet other embodiments, the wound treatment appliance also includes wound packing means to prevent overgrowth of the wound or to encourage growth of the wound tissue into an absorbable matrix comprising the wound packing means. In still other embodiments, the appliance may include a suction drain.

Abstract: A treatment system (100) for debriding an area of a tissue site is disclosed. In some embodiments, the system may include a debridement tool (122) which may be fluidly connected to a negative-pressure source (116) and a fluid source (118). The system may also include a control unit for interfacing with an operator and for regulating the application of negative pressure and delivery of treatment fluid to the debridement tool. The debridement tool may include multiple fluid conduits for delivering and removing fluid to and from the tissue site, as well as a brush (128) for assisting with the removal of necrotic tissue.

Abstract: An apparatus and method for cleansing and applying therapy or prophylaxis to wounds, in which irrigant fluid, which may contain a physiologically active material, and wound exudate from the dressing are moved by a device for moving fluid through a flow path which passes through the dressing. A means for fluid cleansing may also be provided to recirculate fluid back to the dressing. The cleansing means removes materials deleterious to wound healing, and the cleansed fluid, still containing materials that are beneficial in promoting wound healing, is returned to the wound bed. The apparatus may also provide means for distributing such materials in a precise and time-controlled manner over the wound bed. It may also contain a means for providing simultaneous aspiration and irrigation of the wound.

Abstract: A reduced-pressure system for treating a tissue site on a patient includes a distribution manifold that adheres to a tissue site to allow retention without external support. The distribution manifold includes a porous member and a tissue-fixation element. The tissue-fixation element maintains the porous member substantially adjacent to the tissue site while a sealing member is applied. In one instance, the tissue-fixation element is a soluble adhesive that partially covers either the tissue-facing side of the porous member or a tissue-facing side of a fluid-permeable substrate layer that is on the tissue-facing side of the porous member. Other systems, distributions manifolds, and methods are presented.

Abstract: Surgical methods involving cutting and sealing tissue include affixing a first adjunct material to tissue at a treatment site, such as by stapling the adjunct to tissue. A second adjunct material is applied to at least a portion of the first adjunct material such that the second adjunct material interacts with the first adjunct material to form a seal in an area of the tissue covered by at least one of the first and the second adjunct material. The resulting tissue sealing structure, which includes a combination of the two adjuncts, is believed to be superior to the sealing properties of either adjunct alone.

Abstract: The present invention provides a method and device for visualizing and treating an injury, wound or skin using a visual tourniquet and skin patch system made of transparent materials. The inventive bandage system is capable of applying pressure while absorbing bodily fluids away from the wound or skin and providing support for the application of one or more medicaments or a combination of treatment gas and/or medicine. The inventive bandage system enables the practitioner to visually inspect and measure the size of the wound over time without removing or touching the bandage or tourniquet thereby reducing pain and contamination of the wound bed. One embodiment of the inventive bandage system continuously controls the wound bed temperature thereby reducing pain and inhibiting bacterial growth. Other embodiments of the inventive bandage system are used as a visual tourniquet to apply a combination of pressures to a wound or skin.

Abstract: A drainage device (1) particularly for aspiration in case of therapies with aspiration, fistulas, dehiscences of surgical wounds, bedsores, traumas and similar lesions, comprising an aspiration pouch (2) which is supported by a sheet-like element (5) which can be associated with the lesion (10) and is connected to aspiration means (3) by way of a connecting element (4).

Abstract: Apparatus and methods for providing a wound dressing are provided. A wound dressing according to the invention may preferably include a wound-fluid negative pressure treatment (“NPT”) drain and a vacuum/drainage tube comprising a terminus associated with the NPT drain. The dressing may also include a fluid-absorbing/transferring material. The dressing may also include a contour-conforming draping layer for draping over a wound-bed. The draping layer may be in contact with at least a portion of the fluid-absorbing/transferring material. The dressing may also include a vapor sealant sheet that overlies at least a portion of the fluid-absorbing/transferring layer. The material may also include a tube-anchorage component that is in contact with at least a portion of the vapor sealant sheet. The tube-anchorage component may mechanically maintain placement of the NPT drain within the fluid-absorbing/transferring material.

Abstract: A system for treating a linear wound on a patient has a closing dressing bolster for placing on the patient's epidermis over the linear wound, a sealing subsystem for providing a seal over the closing dressing bolster and the patient, and a reduced-pressure subsystem for delivering reduced pressure to the sealing subsystem. The sealing subsystem and reduced pressure subsystem are operable to deliver reduced pressure to the closing dressing bolster. The closing dressing bolster is operable under reduced pressure to develop a inward closing. The closing dressing bolster may include one or more closing members on each side of a center wound area to create the inward closing when under reduced pressure. A compressive force may also be developed. Other systems and methods are presented.

Abstract: A wound treatment appliance is provided for treating all or a portion of a wound. In some embodiments, the appliance comprises an impermeable flexible overlay that covers all or a portion of the wound for purposes of applying a reduced pressure to the covered portion of the wound. In other embodiments, the impermeable flexible overlay comprises suction assistance means, such as channels, which assist in the application of reduced pressure to the area of the wound and removal of exudate from the wound. In other embodiments, the wound treatment appliance also includes a vacuum system to supply reduced pressure to the wound in the area under the flexible overlay. In yet other embodiments, the wound treatment appliance also includes wound packing means to prevent overgrowth of the wound or to encourage growth of the wound tissue into an absorbable matrix comprising the wound packing means. In still other embodiments, the appliance may include a suction drain.

Abstract: A wound treatment appliance is provided for treating all or a portion of a wound. In some embodiments, the appliance comprises an impermeable flexible overlay that covers all or a portion of the wound for purposes of applying a reduced pressure to the covered portion of the wound. In other embodiments, the impermeable flexible overlay comprises suction assistance means, such as channels, which assist in the application of reduced pressure to the area of the wound and removal of exudate from the wound. In other embodiments, the wound treatment appliance also includes a vacuum system to supply reduced pressure to the wound in the area under the flexible overlay. In yet other embodiments, the wound treatment appliance also includes wound packing means to prevent overgrowth of the wound or to encourage growth of the wound tissue into an absorbable matrix comprising the wound packing means. In still other embodiments, the appliance may include a suction drain.

Abstract: Examples include devices, systems and methods related to advanced wound therapy dressings. Specific examples are optimized for use with mobile continuous diffusion of oxygen therapy systems for the localized delivery of oxygen to damaged and healing tissues. Examples may utilize a conduit to deliver therapeutic fluids, including for example oxygen, where the conduit comprises a plurality of apertures or perforations. Examples may also include a spacer material with a plurality of distribution channels in fluid communication with the conduit.

Abstract: One aspect of the present disclosure relates to a method for forming a multipurpose membrane in vivo. One step of the method includes obtaining a blood component. Next, a vacuum assembly is operated to remove substantially all of the liquid from the blood component and thereby form a concentrated, substantially dehydrated blood component. The substantially dehydrated blood component is then formed into a non-coagulated injectable composition and administered to a wound of a subject.

Abstract: Embodiments of the invention include wound packing devices and methods of making and using the same. In an embodiment, the invention includes a wound packing device including a plurality of spacing elements capable of absorbing exudate, wherein the surface of the spacing elements resist colonization by microorganisms. The wound packing device can also include a connector connecting the plurality of spacing elements to one another. Other embodiments are also included herein.

Abstract: The illustrative embodiments described herein are directed to an apparatus and method for managing reduced pressure at a tissue site. The apparatus includes a reduced pressure source that generates reduced pressure. The reduced pressure is delivered to the tissue site via a delivery tube. The apparatus includes a single pressure sensor. The single pressure sensor detects an actual reduced pressure at the tissue site. The apparatus also includes a controller. The controller determines a responsiveness of the actual reduced pressure measured by the single pressure sensor to an increase in reduced pressure generated by the reduced pressure source. The apparatus includes an indicator. The indicator emits a signal when the controller determines that the actual reduced pressure measured by the single pressure sensor is nonresponsive to the increase in reduced pressure generated by the reduced pressure source.

Abstract: Systems, methods, and apparatuses are presented that involve forming patterns on neo-epithelium that allow increased functionality and may more nearly resemble the original epithelium. In one instance, a patterned neo-epithelium dressing for treating a tissue site having granulation tissue includes an interface member for placing proximate the granulation tissue and a plurality of three-dimensional features formed on a second, patient-facing side of the interface member. Other systems, methods, and apparatuses are disclosed.

Abstract: Described herein are alarm systems for suction devices for reduced pressure therapy. Alarms systems provide alerts to the patient and/or practitioner regarding the ability of the suction device to continue to provide negative pressure to a tissue region. Alarm systems comprise a sensor mechanism, which is capable of detecting the position of a slidable seal within the suction device, and generating an alert. Certain variations of alarms systems comprise magnetic field sensitive switches and/or electric switches. Other variations of alarm systems comprise rotary encoders to detect the motion and location of constant force springs, which signal the notification mechanism to issue alerts accordingly. Described herein are alarm devices configured to retain a suction device therein and to attach the suction device to a patient. The alarm devices disclosed herein detect the depleted state of the suction device and are capable of retaining the suction device in a plurality of orientations.

Abstract: Systems and methods for delivery of fluid to a wound therapy dressing. In exemplary embodiments, a pressure sensor measures the pressure at the wound therapy dressing and restricts fluid flow to the wound therapy dressing when a predetermined pressure is achieve.

Abstract: A reduced-pressure treatment system for applying reduced pressure to a tissue site at a limited-access location on a patient includes a reduced-pressure source, a treatment manifold for placing proximate the tissue site and operable to distribute reduced pressure to the tissue site, and a sealing member for placing over the tissue site and operable to form a pneumatic seal over the tissue site. The reduced-pressure treatment system also includes a reduced-pressure bridge and a moisture-removing device on at least portion of the reduced-pressure bridge. The reduced pressure bridge includes a delivery manifold operable to transfer the reduced pressure to the treatment manifold, an encapsulating envelope at least partially enclosing the delivery manifold and having a patient-facing side, and a reduced-pressure-interface site formed proximate one end of the reduced-pressure bridge.

Abstract: A process, method, and devices thereof for the rapid destruction of cancer tumor(s) which are made up of thousands to millions of living malignant cancer cells. Such an approach seeks to kill said tumor(s) by causing apoptosis or excitotoxicity and/or osmotic-shock within a human or animal for medical treatment.

Abstract: Microstrain-inducing manifolds, systems, and methods are presented that involve microstrain-inducing manifolds that include a plurality of shaped projections for creating microstrain. The shaped projections may be tapered projections. A system may include a sealing member for placing over the tissue site, a microstrain-inducing manifold, and a reduced-pressure subsystem that delivers reduced pressure to the sealing member. The reduced pressure causes the shaped projections to create microstrain at the tissue site. Other methods, apparatuses, and systems are also presented.

Abstract: A description of a device and method of use are provided for a containment chamber, accompanying sensing and monitoring instrumentation, and method of creation of a physical force wave that would be capable of mimicking physiologic waves such as pulse pressure, muscle contraction, peristalsis, acoustic waves and other desired waves to be studied. This device allows for the use of various biologic or biologically comparable fluids—alone or in combination—that would allow for the analysis of the passage of these waves through these media. Singularly, this device also allows for the manipulation of the external constraints that mimic the containment of that media in vivo. This allows for the analysis of the effects on the nature of the wave, its reflections, potential augmentation or dampening that occur in conjunction with various selected external and internal (baffle) constraints that mimic those found in nature or in therapeutic interventions.

Abstract: The invention relates to a wound drainage covering for covering, by means of low pressure, a wound that is to be treated. The covering comprises at least two layers that are superimposed. A first layer that is applied on the side of the wound is made of a functional textile material and second layer that is arranged thereon is dimensionally stable and permeable to liquid. The wound drainage covering has a simple design and due to the functional first layer, is effective and ensures, due to the dimensionally stable second layer, an optimal removal of wound secretion.

Abstract: Provided, in one embodiment, is a vacuum wound dressing for covering a wound bed comprising: a wound contact layer comprising a fibrous blend or fibrous material that forms a cohesive gel when wetted by wound exudate; a source of vacuum situated to be separated from the wound bed by the wound contact layer; and a vacuum sealing layer covering the wound contact layer and adapted to retain relative vacuum in the wound contact layer, wherein (i) the dressing is essentially missing a non-gelling, foam layer in which the source of vacuum is situated or (ii) the vacuum sealing layer comprises as an outer layer a foam layer.

Abstract: A device (10) for disinfecting wound treatment is described, with a housing (18), with a plasma generator (54) arranged in housing (18) for generating a disinfecting plasma, with a flow module (52) arranged in housing (18) for generating a gas stream, which forms a free jet (32) transporting the disinfecting plasma from housing (18), and with a jet control unit (50) for affecting the free jet (32) in a planned manner by controlling the gas stream generated by flow module (52). Means (10) has, furthermore, a guide apparatus (56) controllable via the jet control unit (50) for guiding the free jet (32).

Abstract: Thus, systems and methods for a debriding wound vacuum may include a sponge for application to a wound, a flexible sheet for covering and sealing the wound, and a bladder. The bladder may be in fluid communication with at least a portion of the sponge. The bladder preferably contains a debridement substance. A negative pressure device may form part of the system and may be used to apply negative pressure via a hollow tube to the sponge. The negative pressure device may be adapted to apply negative pressure to the sponge via the hollow tube in order form a seal between the flexible sheet and the wound. The systems may also include microelectronic mechanical valves for releasing the debridement substance from the bladder.

Abstract: Wound treatment systems and methods (e.g., having hydrophilic wound inserts), such as for negative-pressure and/or fluid-installation wound therapies. Some embodiments include a check-valve assembly between a wound dressing and a vacuum source.

Abstract: Methods and systems for treating a wound using targeted delivery of magnetically-tagged active agents in combination with negative pressure wound therapy are presented. In particular, a magnetically-active wound insert may be used to attract magnetically-tagged stem cells to a wound site to treat the wound.

Abstract: A wound leakage collection device is described wherein a chamber provides a volume wherein wound leakage material can be removed from vacuum tubing and said device can be easily removed from a wound and a negative pressure source.

Abstract: A mechanical wound therapy (MWT) system includes a connection for a vacuum source, which is routed through an airtight covering to a porous material positioned over the wound. The porous material may be a tubing network interspaced by a netting material constructed of biologically inert or bioabsorbable material. Alternatively, the porous material may be a layered unified dressing in which layers of mesh, netting or thin perforated film are separated and fixedly attached to functional elements of the dressing (e.g., irrigation tubing) or spacers. The vacuum and irrigation systems may be completely separated. An airtight sealing layer or foldable adhesive sealing layer may seal the dressing and facilitate sealing the dressing to the wound margins. Additional modular devices such as a wound approximating system, positive pressure bladders and adjuvant therapy modules as well as enhanced monitoring technology can be added to synergistically increase the capabilities of each dressing.

Abstract: The present invention is to provide a gas mist pressure bathing system enabling to cause a gas mist to be absorbed into the skin and the mucous membrane of the living organism under an optimum condition of controlling the amounts of gas and liquid.

Abstract: A system for applying reduced pressure to tissue includes a multi-lumen reduced pressure delivery tube having a proximate end, a distal end, a primary lumen extending through the conduit from the proximate end to the distal end, and an ancillary lumen extending through the conduit from the proximate end to the distal end. A vacuum pump is coupled to the proximate end of the primary lumen, and a reduced pressure adapter is coupled to the distal end of the reduced pressure delivery tube. The adapter includes channels to direct liquid away from the ancillary lumens and into the primary lumen.

Abstract: A device for use with a negative pressure bandage for supply negative pressure. The device includes a pump module and a controller module. The pump module contains a power source and a pump. The pump module is removably contained in the controller module. The pump module and controller module can be connected with a connector that provides both a physical and pneumatic connection. The controller module may include one of more visual indicators for allowing the status of the device to be observed at a distance.

Abstract: In various embodiments of the invention, the components can include a hemostatic vacuum cup which can utilize ancillary or self-contained vacuum generation, and a therapeutic agent which is supplied prior, simultaneously or subsequent to the application of a vacuum with the ultimate aim of slowing or arresting the flow of blood in a bodily tissue or organ. The invention relates to a hemostatic vacuum cup which can utilize ancillary or self-contained vacuum generation. The cup produces a hemostatic effect by the physical application of the device upon a traumatized tissue site and through the delivery of an agent, such as one that assists in hemostasis, antinociception, coagulation, sterilization, or other effective wound healing agents including antibiotics, antiseptics and antioxidants. The cup can be adapted to deliver the therapeutic agent, by methods integral to the vacuum cup. The therapeutic agent can be delivered in the form of a sponge, cellulose or other filter material.

Abstract: The invention is to provide a gas mist pressure bath system, which is possible to control the amount of gas and liquid, pressure and others, and cause a gas mist to be absorbed through a skin and mucous membrane of a human living body under an optimum condition.

Abstract: According to an embodiment of the present disclosure, a wound dressing system is presented. The wound dressing system includes a fluid permeable support layer, the support layer configured for positioning within a wound and adapted to generally conform to a topography of the wound, and to permit exudates from the wound to pass therethrough. The wound dressing system further includes a plurality of beads supported by the support layer, the beads defining an insulated inter-connected elongate member and an electrode embedded within and extending through at least a portion of the elongate member. Also, a current is generated by an external energy source that electrically flows through the electrode.

Abstract: The invention is to provide a gas mist pressure bath system, which is possible to control the amount of gas and liquid, pressure and others, and cause a gas mist to be absorbed through a skin and mucous membrane of a human living body under an optimum condition.

Abstract: Embodiments of the present invention are directed to various designs and packaging methods for a gas delivery device and materials for supplying one or more predetermined gases to a target area as well as to application specific opthamological embodiments. With regard to the gas delivery device, the device may include a reservoir, a gas diffusion portion for communicating gas from the reservoir and one or more predetermined gases at concentrations greater than atmospheric contained within the reservoir, wherein the device does not generate gas and may be packaged prior to use with the one or more predetermined gases.

Abstract: An endoluminal and intracorporeal negative pressure, wound care treatment, and prophylaxic system 10 and method includes a pressure distributor 40 for placement substantially within an internal organ or tissue abscess 34. A fluidic communication means 22 is provided between the pressure distributor 40 and a negative pressure source 20. A collection canister 24 is provided between the negative pressure source 20 and the pressure distributor 40 for collecting any effluents 36 that may be drawn from the abscess 34 during application of negative pressure. An introducing conduit 44 is provided for introducing the pressure distributor 40 into the abscess 34. A positioning conduit 46 is provided to properly position the pressure distributor 40 within the abscess 34. Negative pressure is applied to the pressure distributor 40 in order to provide negative pressure therapy within the abscess 34.

Abstract: Wound dressings and wound inserts comprising substantially dry reactive agents, methods of forming wound inserts comprising dry reactive agents, and wound-treatment methods.

Abstract: A method, and apparatus for the controlled acceleration, and/or retardation of the body's inflammatory response generally comprises a foam pad for insertion substantially into a wound site, a heating, a cooling pad for application over the wound site, a wound drape or sealing enclosure of the foam pad, the heating, and cooling pad at wound site. The foam pad is placed in fluid communication with a vacuum source for promotion of the controlled acceleration or retardation of the body's inflammatory response. The heating, and cooling provision controls the local metabolic function as part of the inflammatory response.

Abstract: Systems and methods for longevity, anti-aging, fatigue management, obesity, weight loss, weight management, delivery of nutraceuticals, and treating hyperglycemia, Alzheimer's disease, sleep disorders, Parkinson's disease, Attention Deficit Disorder and nicotine addiction involve synchronizing and tailoring the administration of nutraceuticals, medications and other substances (for example, stimulants) in accordance with the body's natural circadian rhythms, meal times and other factors. Improved control of blood glucose levels, extended alertness, and weight control, and counteracting of disease symptoms when they are at their worst are possible.

Abstract: A reduced pressure treatment apparatus includes a charging chamber storing a first pressure less than an ambient pressure and a regulated chamber storing a second pressure less than the ambient pressure. The first pressure is less than the second pressure. A conduit provides fluid communication between the regulated chamber and the charging chamber. A regulator member is operably associated with the conduit to prevent fluid communication through the conduit when the second pressure is less than or equal to a desired therapy pressure and to allow fluid communication through the conduit when the second pressure exceeds the desired therapy pressure.

Abstract: A vacuum system for draining an open wound from liquids exuded therefrom, comprising an enclosure sealable to the wound circumference, a vacuum pump including a disposable pump unit detachably attachable to a non-disposable drive unit, and a waste container for collection of drained liquids. The enclosure has an outlet connected by means of a tube to an inlet of the pump unit and the waste container is connected to an outlet of the pump unit, such that when the vacuum pump is operated the drained liquids flow through the vacuum pump. The enclosure has one or more bleeding holes provided therethrough or adjacent to its outlet so that ambient air may enter the tube and flow together with the drained liquids. The enclosure and the waste container are disposable so that the drained liquids contact only disposable elements and may be disposed of together with all disposable elements.

Abstract: Apparatus and methods to treat skin defects include a pump with reservoirs for a pressurization gas and a fluid. Upon activation, the pump generates a gas introduced into the gas reservoir, a movable wall of which displaces a movable wall of a fluid source, thus dispensing the fluid into the dressing to spread throughout irrespective of orientation of the dressing, maintaining a transport fluid (e.g. carrier) in the dressing and in contact with a skin defect being treated. The dressing may have a distribution network, and multiple members, dispensing the fluid into the dressing and in contact with a skin defect being treated.

Abstract: An apparatus for stimulating healing of a wound, includes a porous pad adapted to contact a surface of the wound on an affected part of a body. An envelope for receiving the porous pad and the affected part of the body is provided, and the envelope includes a re-sealable opening that permits the wound to be inspected. A connector is fluidly connected to an interior of the envelope and to a source of negative pressure.

Abstract: A surgical tissue therapy device includes a sealant layer and a collection chamber. The sealant layer functions so as to create a sealed enclosure or space between it and the surface of a patient by forming, preferably, an airtight seal around a surgical area of skin trauma. The closed incision tissue therapy device also comprises a collection chamber, which may comprise an elongate tubular chamber with a plurality of longitudinally spaced openings. The collection chamber may be configured to be in fluid communication with the sealant layer and the area of skin trauma and functions as to distribute the negative pressure applied to a surgically closed area of skin trauma. Preferably, the pressure under the sealant layer is reduced by expanding the volume of the enclosure space and thereby decreasing the density of air molecules under the sealant layer.

Abstract: A method and apparatus for measuring a volume of a wound are described, the method comprising the steps of: applying a dressing over a wound, the volume of which is to be measured, the dressing including at least a sealing drape over the wound so as to create a sealed wound cavity; creating a vacuum in said wound cavity by vacuum pump means so as to produce a predetermined vacuum in the wound cavity; measuring a volume of air extracted from said wound cavity in producing said predetermined vacuum; and, calculating a volume of said wound.

Abstract: A device for treating wounds with negative pressure is provided that includes an adhesive film that defines a chamber in relation to the wound; a vacuum source can be adjusted to produce negative pressures in the same chamber; a canister for collecting liquids drained from the wound; a reservoir containing medicated liquids to be instilled in the wound; an unit for setting both the negative pressure and the quantity of administered medication; and a pressure sensor to detect the negative pressure present in said chamber. The device further includes a spiral diffuser mounted on said film comprising a high number of protrusions on tube coils, the spiral diffuser being connected both to vacuum source and to a pump; micro-valves for diffusing medicated liquids, one for each protrusion on coiled tube of spiral diffuser; and a pump administering medicated liquids exerting a pressure capable of opening the micro-valves present in protrusions.

Abstract: A medical device for example a wound dressing having antibacterial and optionally, antifungal properties, are provided together with methods for making the device. An exemplary dressing includes a layer of silver-containing fabric, (optionally) a layer of absorbent material, and (optionally) a layer of flexible air-permeable and/or water-impermeable material. The dressing can be used for prophylactic and therapeutic care and treatment of skin infections and surface wounds (including surgical incisions), as a packing material, and as a swab for surface cleaning.