Abstract: The invention relates to a tilt and slide cover in a vehicle roof. The tilt and slide cover comprises a cover and a frame, which is supported in lateral guides of a roof opening. The special feature of the tilt and slide cover lies in the fact that the cover is arranged relatively moveable in relation to the frame and can be locked to and released from this. The frame comprises a plastic section, into which the slide guide and other fittings such as slide cheek holders or the like can be integrated in one piece. It is also possible to fix the rear water collection channel directly on the frame.

Abstract: This disclosure describes example adhesive medical patches that may be used in combination with one or more antimicrobial agents to create and/or maintain an area of human skin that is free from contaminants. According to some embodiments, the disclosure describes that the adhesive patches may contain an adhesive material affixed to the perimeter of an impermeable backing According to some embodiments, the adhesive patch may also have a permeable layer containing an antimicrobial agent located interior to the adhesive material on the impermeable backing.

Abstract: A medical adhesive patch, includes: a support film including a barrier layer which contains a water-soluble polymer compound and montmorillonite, and which is laminated on one surface of a support including polyurethane; an adhesive layer which contains a medicine and a plasticizer, and which is laminated on a barrier layer of the support film, the medical adhesive patch has a percentage content of montmorillonite in the barrier layer is equal to or more than 2 percent by weight and equal to or less than 22 percent by weight.

Abstract: A flexible pneumostoma management device maintains the patency of a pneumostoma while controlling the flow of material through the pneumostoma. The pneumostoma management device includes flange attaches to the chest of the patient to secure the device in position. The pneumostoma management device also includes a tube which enters the pneumostoma to allow gases to escape the lung. The length of the tube is selected to match the dimensions of the pneumostoma of a patient. In order to manufacture devices having different tube lengths, the tube is formed at a longer length than required, cut to size and tipped. The tube may be formed by molding or extrusion.

Abstract: The present invention relates to a patch preparation having a central part and a peripheral part surrounding the central part, the patch preparation comprising: a patch preparation main body having a support and an adhesive layer which contains a drug and is formed on the support; and a release liner laminated on the adhesive layer, wherein the peripheral part has a predetermined area, and a peel force between the adhesive layer and the release liner in the predetermined area is greater than a peel force between the adhesive layer and a release liner in the central part.

Abstract: The present, invention relates to a transdermal absorption preparation. The transdermal absorption preparation of the present invention comprises a drug-containing adhesive layer, a drug-protective layer and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, rubber, an adhesion-imparting resin, an antioxidant, and a transdermal absorption promoter. Also, the present invention provides a transdermal absorption preparation comprising a drug-containing adhesive layer, a drug-protective layer, and a release layer, wherein the drug-containing adhesive layer contains ropinirole or a salt thereof, acrylic rubber, an anti-crystallisation agent, and a transdermal absorption promoter. When the transdermal absorption preparation of the present invention is used for the treatment of Parkinson's disease or restless leg syndrome, no side effect due to an increase in the initial drug concentration in blood occurs and the skin penetration effect of the drug is excellent.

Abstract: Provided are a skin patch sheet including a carrier sheet, an adhesive patch and a release liner laminated in this order, in which (a) the adhesive patch includes two layers, namely, a backing and an adhesive layer having the same shape; (b) the carrier sheet is adjacent to the backing of the adhesive patch; (c) the skin patch sheet includes a grip section and a body section; (d) in the body section or the body section and grip section, the area of the release liner is larger than the area of the adhesive patch; (e) the boundary between the grip section and the body section is a slit line formed by a slit; and (f) the slit extends from the side of the release liner, penetrating into the adhesive patch, up to a depth in the range of greater than or equal to 20% and less than 50% of the thickness on the adhesive patch side of the carrier sheet; a skin patch sheet in which plural sheets of adhesive patches on which carrier sheets are laminated are formed in a parallel arrangement on a release liner; use of the s

Abstract: A pneumostoma management system which includes a pneumostoma management device and a cover. The pneumostoma management device maintains the patency of a pneumostoma while controlling the flow of material through the pneumostoma. The pneumostoma management device includes a hydrophobic filter and/or a one-way filter. The cover serves to protect the pneumostoma management device and/or provide a cosmetic skin to make the pneumostoma management device more acceptable to the patient and thereby encourage patient compliance with a pneumostoma treatment regimen.

Abstract: Methods and systems are provided for a sub-atmospheric wound-care (SAWS) system for treating an open wound. The SAWS system includes a regulated vacuum source for developing a negative pressure, a flow rate meter configured to measure a flow rate of liquid removed from the wound, a primary pressure regulating sensor located proximate the wound for directly measuring the negative pressure at the wound, a backup pressure regulating sensor located vacuum tube, a porous dressing suitable to be sealed airtight which is positioned within a wound interface chamber, a collection canister configured to collect said liquid removed from the wound, and an adapter configured to use wall suction a primary regulated vacuum source.

Abstract: A wound-closing dressing, which is suitable for use as part of a reduced-pressure, wound-treatment system, may include a sealing drape, one or more contracting elements, and a gripping member. The contracting element may be coupled to the sealing drape and is configured to contract when activated and to generate a closing force. A gripping member is coupled to the sealing drape and is configured to transmit the closing force to a patient's epidermis. Other dressings, systems, and methods are also disclosed.

Abstract: A wound therapy device is disclosed. The wound therapy device may include a housing for covering at least a portion of a wound and for sealing to a body surface of a patient. The housing may also include a liquid collector for retaining liquid therein and a vacuum connection for coupling to a vacuum source. The vacuum connection may be in gaseous communication with the liquid collector. The vacuum connection may be separated from the liquid collector by a liquid barrier.

Abstract: A medical adhesive patch includes: a support film including a barrier layer which contains polyvinyl alcohol and a layered inorganic compound, and which is laminated on one surface of a support including polyurethane; an adhesive layer which contains a medicine, and which is laminated on the barrier layer of the support film, a degree of saponification of the polyvinyl alcohol is equal to or more than 70% and equal to or less than 95.5%.

Abstract: A preparation for the transdermal delivery of a biologically active substance into the body of a patient comprises particles of a formulation comprising the active substance. The particles are irregular in size and shape and may be produced by a low cost manufacturing method such as grinding from a thin film. The particles are angular, i.e. they have sharp edges and corners that allow them to penetrate the outer layer of the skin when subjected to pressure from a roller or an array of blunt-tipped microstructures. Sucrose may be used as an excipient with the active substance to form suitably rigid and angular particles.

Abstract: A pneumostoma management system for maintaining the patency of a pneumostoma while controlling the flow of material through the pneumostoma. The pneumostoma management system includes a two-part pneumostoma management device and associated insertion and removal tools. The pneumostoma management device includes a pneumostoma vent and a chest mount for positioning and securing the vent into a pneumostoma. The pneumostoma vent includes a hydrophobic filter and/or a one-way valve.

Abstract: A flexible pneumostoma management device maintains the patency of a pneumostoma while controlling the flow of material through the pneumostoma. The pneumostoma management device includes a pneumostoma vent having a tube which enters the pneumostoma to allow gases to escape the lung, a flange and a filter/valve to control flow of materials through the tube. The flange is a thin flexible patch which conforms and attaches to the chest of the patient. The flange secures the tube in position in the pneumostoma. The flange is formed in one piece with the tube.

Abstract: A bandage is described comprising a rubber-based adhesive and a flexible substrate that is particularly adapted for application onto warts located on the ends of human digits. The flexible substrate is waterproof, skin-colored and shaped in various ways so as to securely attach onto the ends of human fingers and toes. The shape of the bandage promotes long-term use of the bandage to induce the body's inflammatory response and to prevent transmission of the wart virus to other persons.

Abstract: The present invention relates to a backing having a three-layer structure prepared by sticking together an inner fiber layer for holding a pasty preparation, a film layer having through-holes, and an air-permeable outer fiber layer which prevents leaking out of the pasty preparation or a liquid component exuded from the pasty preparation, and also relates to an aqueous patch using the backing which can be applied for a long time.

Abstract: The present invention is directed to a nonaqueous pressure-sensitive adhesive that may be used in medicinal tape preparations for percutaneous absorption. The adhesive may comprise a copolymer obtained by copolymerization of a (meth)acrylic monomer having an acetoacetyl group in the molecule and one or more monomers from among other (meth)acrylic monomers without acetoacetyl groups and copolymerizable vinyl monomers, in a nonaqueous solvent. Suitable (meth)acrylic monomers having an acetoacetyl group in the molecule are acetoacetoxyalkyl methacrylates, and especially 2-acetoacetoxyethyl methacrylate. The pressure-sensitive adhesive of the invention uses no polyamine derivatives, isocyanate compounds, polyvalent metal chelate compounds, etc., as crosslinking agents, and therefore toxicity is not a concern and skin is not irritated. A medicinal tape preparation for percutaneous absorption of the invention has superior adhesive strength and cohesive strength, and is highly safe with low skin irritation.

Abstract: Wound treatment dressings comprising combinations of at least one conductive layer, at least one absorbent layer or a moisture regulation layer, and methods of making and methods of use are disclosed for treatment of wounds in humans and animals. The novel dressings aid in healing by helping restore the transepithelial potential of the skin, providing a functional anti-microbial barrier, and allowing for regulation of the moisture content of the wound without disturbing the wound.

Abstract: A therapeutic device includes a fluid mover for one of raising, compressing, or transferring fluid, a therapeutic member operably connected to the fluid mover and actuated thereby, the therapeutic member operably disposably used on a patient in a manner to deliver therapy to the patient as function of actuation of the fluid mover, a controller operably associated with the fluid mover for controlling operation thereof, and a leak, blockage, temperature, voltage or current sensor operably connected to the fluid mover and the controller and to sense a leak, blockage, temperature, voltage or current in the device and send a signal to the controller whereby the controller controls the fluid mover as a function of the sensed signal.

Abstract: The composite wound dressing apparatus promotes healing of a wound via the use of a vacuum pump. The vacuum pump applies a vacuum pressure to the wound to effectively draw wound fluid or exudate away from the wound bed. The vacuum pump is tethered to the wound dressing and is portable, preferably, carried by the patient in a support bag, which permits patient mobility. Moreover, the patient does not need to be constrained for any period of time while exudate is being removed from the wound.

Abstract: A device for delivering oxygen to a wound or injury includes a bandage, which includes a base defining an opening, a cover, and a locking mechanism for releasably securing the cover to the base. An oxygen source is in fluid communication with the cover, whereby oxygen is delivered to the opening in the base.

Abstract: A flexible pneumostoma management device maintains the patency of a pneumostoma while controlling the flow of material through the pneumostoma. The pneumostoma management device includes a pneumostoma vent having a tube which enters the pneumostoma to allow gases to escape the lung, a flange and a filter/valve to control flow of materials through the tube. The flange is a thin flexible patch which conforms and attaches to the chest of the patient. The flange secures the tube in position in the pneumostoma.

Abstract: An ostomy device that comprises an adhesive wafer for attaching to the skin around the stoma. The wafer comprises an adhesive layer having a proximal adhesive side and a distal side, where the distal side is covered with a backing layer. The wafer comprises a central portion and a peripheral portion, and it comprises a proximal section located on the proximal side of the central portion and a distal section visually arranged on the distal side of peripheral portion, wherein the distal section changes colour when the proximal section is exposed to fluid.

Abstract: A wound dressing apparatus includes a wound dressing member dimensioned for positioning relative to a wound bed. The wound dressing member including an internal vacuum reservoir and has a port in communication with the vacuum reservoir for applying subatmospheric pressure to the vacuum reservoir to facilitate removal of fluid from the wound bed. The wound dressing member includes a visual pressure indicator associated therewith for indicating a level of pressure within the vacuum reservoir. The visual pressure indicator includes color indicia having a plurality of colors corresponding to a condition of the pressure within the vacuum reservoir. The wound dressing member includes a lower absorbent member positionable adjacent the wound bed and an upper member which at least partially defines the vacuum reservoir. At least one of the top member and the lower absorbent member has the visual pressure indicator mounted thereto.

Abstract: An adhesive patch configured to attach an ostomy appliance to a patient includes a peripheral rim disposed around a central hole that is attachable to a stoma of the patient; and a band of adhesive extending from the peripheral rim to an inner border of the adhesive patch and having a pattern of curvilinear indentations extending to the peripheral rim of the patch.

Abstract: Adhesive tape for use in connection with treatment of injuries is described. Tape may be configured to relieve pressure and increase circulation at the injury site, as well as deliver a topical drug solution, including NSAID solutions. Elements such as drug solutions, adhesive, water soluble gels, and so forth may be disposed in patterns configured to increase efficacy and user comfort.

Abstract: Provided is an adhesive patch including a stretchable support and an adhesive layer laminated on at least one side of the support, wherein the stretchable support comprises a woven fabric knitted in stockinette stitch on both sides having two or more rows of crimped polyethylene terephthalate multifilament yarns, the adhesive layer contains 25 to 50% by mass of a liquid organic ingredient and 25 to 50% by mass of a thermoplastic elastomer based on the total mass of the layer and contains 10% by mass or more of methyl salicylate as the liquid organic ingredient based on the total mass of the layer, and the storage elastic modulus (G?) of the adhesive layer is 30000 to 75000 Pa at 10 rad/s and 37° C.

Abstract: This invention relates to the use of agents that modulate claudin-1 and/or -23 expression or activity for purposes of regulating tight junction (“TJ”) formation among keratinocytes that express claudin-1 and/or -23, or other cell types that over- or under-express claudin-1 and/or -23. Several aspects of the present invention relate to increasing claudin-1 and/or -23 expression or function to enhance tight junction formation among claudin-1 and/or -23 expressing cells, particularly keratinocyte and antigen presenting cells. Several other aspects of the invention relate to decreasing claudin-1 and/or -23 expression or function to diminish tight junction formation among claudin-1 and/or -23 expressing cells, particularly keratinocytes and antigen presenting cells.

Abstract: To provide a wound dressing having absorbability and improved so as not to be adhere to wounds, a wound dressing 10 is provided, which includes a perforated material 20 having a top face and a bottom face and having plural through-holes 21, and an absorbent material 30 disposed on the top face of the perforated material, and in which at least the bottom face of the perforated material 20 is coated with a silicone resin 40 except leaving at least a part of the through-holes so as not to block up all the through-holes, and at least a part 31 of the absorbent material facing the through-holes of the perforated material is coated with the silicone resin 40, and to allow fluid penetration from the bottom face side of the perforated material into the inside of the absorbent material.

Abstract: A tissue treatment apparatus and method are provided for treating tissue by the application of the time-varying sub-atmospheric pressure. The apparatus includes a cover adapted to cover a wound and adapted to maintain sub-atmospheric pressure the site of the wound. The apparatus further includes a source of suction configured to generate a time-varying sub-atmospheric pressure having a periodic waveform comprising a gradual change in pressure. The suction source cooperates with the cover to supply the time-varying sub-atmospheric pressure under the cover to the wound. The time-varying sub-atmospheric pressure may vary between a first pressure value below the inherent tissue tension of the wound tissue and a second pressure value above the inherent tissue tension of the wound tissue.

Abstract: The present invention is an ostomy-bag cover that provides a waterproof covering for an ostomy bag. This permits a patient wearing an ostomy bag to shower or bathe without getting his or her ostomy bag wet. In some embodiments, the ostomy-bag cover is constructed such that the patient can engage in water related activities, including swimming, while wearing the ostomy-bag cover over the ostomy bag and prevent the ostomy bag from getting wet. In some embodiments, the ostomy-bag cover includes a resealable opening configured to allow the patient to empty the ostomy bag without the need to remove the ostomy-bag cover. In other embodiments, the ostomy-bag cover includes a waterproof exhaust vent to allow air to be removed from the ostomy-bag cover.

Abstract: Medical dressings and medical dressing kits that can be used to provide a ported medical dressing for placement over a wound or other body site where controlled fluid access is desired. The controlled fluid access provided by the medical dressings may be useful to remove fluids from the wound (as in, e.g., negative or reduced pressure therapies), to provide one or more gases to a wound site, to provide one or more liquids to a wound site, and/or to provide one or more active agents to a wound site. To achieve controlled fluid access, the medical dressing and medical dressing kits may include a port body with a lower surface that is adhesively adhered to the skin at the periphery of a wound or other body site.

Abstract: A flexible pneumostoma management device maintains the patency of a pneumostoma while controlling the flow of material through the pneumostoma. The pneumostoma management device includes a pneumostoma vent having a tube which enters the pneumostoma to allow gases to escape the lung, a flange and a filter/valve to control flow of materials through the tube. The flange is a thin flexible patch comprises of multiple thin layers of materials and which conforms and attaches to the chest of the patient. The flange includes a filter, a protective outer layer and an inner hydrocolloid layer. The flange secures the tube in position in the pneumostoma.

Abstract: The present invention provides a patch preparation that has an extremely low moisture permeability, has a sufficient ODT effect, is excellent in drug releasability and in anchoring property of its drug-containing pressure-sensitive adhesive layer, and has a preferred patch feeling. The patch preparation of the present invention includes a support; and a pressure-sensitive adhesive layer containing an adherent polymer and a drug on one surface of the support, wherein: the support has a polyester base layer, an inorganic oxide layer, and a polyester nonwoven fabric layer in the stated order; the polyester base layer has a thickness of 1.0 ?m to 16 ?m; and the pressure-sensitive adhesive layer is laminated on the polyester nonwoven fabric layer.

Abstract: Skin rejuvenation system and method in which a pure plant collagen carrier is saturated with a solution of collagen, allantoin, amino acid, propanediol, glycerin, algae, plant DNA living cells, epidermal growth factor, Vitamin E, hyaluronic acid, rose essential, water, and peptide, and the saturated carrier is applied to the skin to be rejuvenated.

Abstract: This invention relates to a transdermal drug delivery device that comprises an active ingredient (AI) layer, having a skin contacting surface and a non-skin contacting surface and comprising a volatile component, a release liner impermeable to the volatile component adjacent the skin contacting surface of the Al layer having a perimeter that extends beyond the perimeter of the AI layer in all directions, and an overlay comprising a pressure sensitive adhesive (PSA) that does not absorb the volatile component adjacent the non-skin contacting surface of the Al layer having a perimeter of which extends beyond the perimeter of the Al layer in all directions, wherein the release liner and the PSA of the overlay are in contact with and adhered to each other around the perimeter of the Al layer to form a seal that reduces or prevents volatile component loss.

Abstract: The present invention relates to a repositionable bandage including an adhesive hydrocolloid mass, wherein said bandage includes, on at least one portion of the surface of the adhesive mass intended for being in contract with the wound when the bandage is being used, a web of microfibers or nanofibers, at least 90% and preferably at least 95% of which being made up of one (or more) material(s) selected among natural or synthetic polymers, and being suitable for solubilizing or gelling in under ten seconds, and preferably still in less than one second when in contact with the exudate from the wound. The bandage according to the invention is intended for treating wounds such as blisters, exuding wounds, burns and dermal-epidermal lesions, whether superficial, deep, chronic or acute.

Abstract: A biodegradable wound care product with biocompatible artificial skin treatment. It includes a biodegradable bandage support member and a biodegradable adhesive on at least a portion thereof. The support member is made of a biodegradable material, such as natural or artificial textiles, plastics or papers. A biodegradable actives carrier is attached to a portion of the biodegradable bandage support member and is a synthetic or natural biodegradable adhesive or a combination thereof. An active ingredient is located on the biodegradable actives carrier including a layer of biocompatible algae artificial skin including sterilized water and at least 60% by weight of reconstituted seaweed, preferably Laminaria seaweed. A healing accelerator that is an alpha keto acid or an alpha keto acid derivative is also included.

Abstract: The present invention relates to a bandage including an adhesive hydrocolloid mass, wherein said bandage includes, on at least one portion of the surface of the adhesive mass intended for being in contract with the wound when the bandage is being used, a plurality of agglomerates made up of particles linked to one another, preferably in a multi-layer configuration, at least 90% and preferably at least 95% of said particles being made up of one (or more) material(s) selected among polysaccharides, proteins and synthetic polymers, and being suitable for solubilizing or gelling in under ten seconds, and preferably still in less than one second when in contact with the exudate from the wound. The bandage according to the invention is intended for treating wounds such as blisters, exuding wounds, burns and dermal-epidermal lesions, whether superficial, deep, chronic or acute.

Abstract: An anal patch comprising an absorbent pad (3) in a shape with two substantially parallel flat surfaces and a contact surface perpendicular to the flat surfaces, the area of the contact surface being smaller than each of the two parallel flat surfaces, an adhesive part, comprising an adhesive coated backing layer (4), having a central aperture (8) wherein at least a part of the contact surface of the absorbent pad is aligned with the aperture of the adhesive part.

Abstract: A flexible pneumostoma management device maintains the patency of a pneumostoma while controlling the flow of material through the pneumostoma. The pneumostoma management device includes a pneumostoma vent having a tube which enters the pneumostoma to allow gases to escape the lung, a flange and a filter/valve to control flow of materials through the tube. The flange is a thin flexible patch which conforms and attaches to the chest of the patient. The flange secures the tube in position in the pneumostoma. The device has features to control secretions from the pneumostoma. The secretion management features include, ridges, pores, absorbent materials, and combinations thereof.

Abstract: The invention is intended to provide an adhesive patch which effectively inhibits the occurrence of oozing out or sticking out of the adhesive layer components from the exposed area of the adhesive layer of the adhesive patch during storage as well as the occurrence of oozing of bisoprolol or a salt thereof from the adhesive layer thereby preventing the reduction in drug content. The support, the release liner and the adhesive layer constituting the adhesive patch each are formed to have a rectangular planar shape and the entire adhesive patch are formed to have a rectangular planar shape, and a protrudent part is formed on the support-side surface of the adhesive patch at a corner thereof. In addition, the adhesive patch may be formed to have a middle part and a peripheral part, and the protrudent part may be formed at a corner of the rectangular middle part.

Abstract: A pneumostoma management device for maintaining the patency of a pneumostoma while controlling the flow of gases and discharge through the pneumostoma. The pneumostoma management device includes a bulb connected to a tube which enters the pneumostoma. A flow control device regulates air flow in and out of the pneumostoma via the tube. A hydrophobic filter traps discharge in the bulb while allowing gases to escape.

Abstract: An applicator (1) for applying an article (2) to the skin (3) of a patient comprising a liner (4), an article carrying layer (5) and an applicator layer (6), and where the article carrying layer (5) has a bottom (7) and a top (8) surface, both being delimited by the periphery (9) of the carrying layer (5), and where the bottom surface (7) comprises an article carrying area (10), where the article (2) is fixed to the carrying layer (5), and an adhesive area (11) being releasably adhered to a surface (12) on the liner (4) by means of a first adhesive, and where the applicator layer (6) has a surface (13) being releasably adhered to only a first part (14) of the top surface (8) of the article carrying layer (5) and its periphery (9), by means of a second adhesive, and where the first and the second adhesives are selected so that, when the applicator layer (6) is pulled away from the liner (4) in an area where the applicator layer (6) and the second adhesive covers the first part of the periphery of the article c

Abstract: The present invention relates to a percutaneous absorption preparation which can administer an anti-dementia drug stably and efficiently for a long period such as one week. More specifically, the present invention relates to a percutaneous absorption preparation comprising a drug-containing layer comprising an anti-dementia drug, a polymer compound having an amino group, a polyhydric alcohol fatty acid ester, a polyhydric alcohol, a polyvalent carboxylate ester, and a styrenic polymer compound.

Abstract: The invention is intended to provide an adhesive patch which contains a drug except bisoprolol and which effectively inhibits the occurrence of oozing out or sticking out of the adhesive layer components from the exposed area of the adhesive layer of the adhesive patch during storage as well as the occurrence of oozing out of the drug from the adhesive layer thereby preventing the reduction in drug content. The support, the release liner and the adhesive layer constituting the adhesive patch each are formed to have a rectangular planar shape and the entire adhesive patch are formed to have a rectangular planar shape, and a protrudent part is formed on the support-side surface of the adhesive patch at a corner thereof. In addition, the adhesive patch may be formed to have a middle part and a peripheral part, and the protrudent part may be formed at a corner of the rectangular middle part.

Abstract: A transdermal therapeutic system for administering lipophilic, poorly water-soluble and/or sparingly skin-permeable pharmaceutical active substances. The active substance is present in a multi-component enhancer system consisting of 4 components and each component of the multi-component enhancer system is selected from a different one of the substance groups: a) terpenes, b) cyclic glucitol ethers, c) medium-chain triglycerides of capric and caprylic acid and/or of linoleic acid; and d) longer-chain alcohols having a chain length of 8 or more carbon atoms.

Abstract: A tape preparation is provided which does not use a backing such as a plastic film, knit or a woven fabric, or a nonwoven fabric, has very high conformability to skin, and is easy to use at the time of application. There is provided a tape preparation 1 that is produced by laminating a drug-containing adhesive layer 4 on the printed ink layer 3 side of a cover film 2 with printing thereon and covering the drug-containing adhesive layer with a release film 5. In this tape preparation, the adhesive strength between the cover film and the printed ink layer is higher than the adhesive strength between the drug-containing adhesive layer and the release film, and the adhesive strength between the printed ink layer and the drug-containing adhesive layer is higher than the adhesive strength between the cover film and the printed ink layer.

Abstract: A synchronized water is disclosed, in which all single water molecules at the same time are arranged in an identical way to a stable homogeneous microstructure, wherein said synchronized water in a distilled condition and at atmospheric pressure has a) a density of from 0.997855 to 0.998836 g/ml at 22° C., b) a water temperature at the freezing point of from ?6.7° C. to ?8.2° C., c) a melting point of from 0.1° C. to 0.2° C., d) a surface tension of from 72.3 to 72.7 dyn/cm at 22 and e) a dielectric constant of from 82.4 to 82.6 F/m, as well as a method for preparation thereof and different uses thereof.