Abstract: The present invention provides an integrated infusion system having a drug vial container adapted to hold a drug vial, the drug vial container having a drug vial holder element and a holder cap element, wherein the drug vial holder element and the holder cap element are fused together forming a seal; and a chemical indicator inside the drug vial container for sterility verification.

Abstract: A fill adapter system for an infusion pump assembly. The system includes a reusable fill adapter base, the base including a volume control mechanism to adjust an available fill volume of a reservoir of the infusion pump assembly and a pump mechanism configured to pump air into a fluid vial.

Abstract: A closure for dispensing one or more active agents into a container comprises a sealed or sealable chamber having a breakable wall and a hollow piston slidably mounted in a piston guide. Said hollow piston comprises an outer wall having an end in the chamber and at least one ventilation aperture. Said end has a cutting formation. Said hollow piston is slidable in the piston guide between a ventilation position in which the at least one ventilation aperture allows ventilation of the chamber and a sealed position in which the at least one ventilation aperture is sealed to prevent ventilation of the chamber and a deployed position in which the cutting formation has broken through at least a portion of the breakable wall. The outer wall has a retaining formation which engages with the piston guide to releasably resist sliding of the hollow piston between the ventilation position and the sealed position and the deployed position.

Abstract: A closed fluid transfer system for fluidly interconnecting a syringe to any one of a patient I.V. set, a vial and an I.V. bag, is provided and includes a first adapter defining a lumen and supporting a seal across a first end of its lumen, the first adapter supporting a rear end of a needle within the lumen, wherein the seal is movable relative to the needle such that a tip of the needle penetrates through the seal; and a second adapter defining a lumen and supporting a seal across a first end of its lumen; wherein when the second adapter is coupled to the first adapter, the second adapter seal abuts the first adapter seal and moves the first adapter seal relative to the tip of the needle such that the tip of the needle penetrates through the abutting first adapter seal and second adapter seal.

Abstract: The present invention relates to a medical device connector for connecting a piercing device, with a vial comprising a base member. A plurality of grip members, each grip member comprising a distal end (D) and a proximal end (P) and each comprising a wedge portion adapted to temporarily or permanently lock the medical device connector to the vial. The base member further comprises a plurality of flanges, wherein the proximal ends (P) of the grip members are arranged to the flanges. The flanges extend substantially out from the periphery of the base member in a direction substantially perpendicular to the direction of the grip members, wherein the space formed between the flanges of the base member forms at least one grip portion. The present invention provides for a medical device connector which is easy and comfortable to use, which provide good stacking capabilities and which permits a user to readily acknowledge that the medical device connector is correctly assembled with the vial.

Abstract: A syringe device includes an administration holder, and a cylinder portion which allows insertion of the administration holder. The cylinder portion includes a coupling holder, a slit holder coupled to the coupling holder, and a double-ended needle assembly disposed slidably in an interior of the coupling holder. A cartridge for a freeze-dry product is mounted, in the administration holder, and a cartridge for solvent is mounted in the coupling holder. When the administration holder is pushed, the double-ended needle assembly slides. When one of the needle points pricks the cartridge for freeze-dry product, the other needle point of the double-ended needle assembly pricks the cartridge for the solvent, and then the needle points unseal the cartridges by a further sliding movement of the double-ended needle assembly.

Abstract: A fill adapter system for an infusion pump assembly. The system includes a reusable fill adapter base, the base including a volume control mechanism to adjust an available fill volume of a reservoir of the infusion pump assembly and a pump mechanism configured to pump air into a fluid vial.

Abstract: A cap for coupling to a medical adapter may include a housing with a closed top end and an open bottom end with legs that extend from the housing away from the bottom end. Members may extend from an inner surface of the legs to engage and secure the cap to a medical adapter or an insert configured to mate with a medical adapter. A cap may include angular ridges between a cap housing and an insert to permit rotation of the cap in single direction and prevent removal of the cap from a medical adapter. A cap may include hinged legs to permit the cap to be secured to a medical adapter by rotating the legs toward each other until a portion of a collar on each leg may be matingly joined around the medical adapter.

Abstract: A fill adapter system for an infusion pump assembly. The system includes a reusable fill adapter base, the base including a volume control mechanism to adjust an available fill volume of a reservoir of the infusion pump assembly and a pump mechanism configured to pump air into a fluid vial.

Abstract: Liquid drug transfer devices employing manual rotation of a drug vial adapter with respect to a liquid container adapter for dual flow communication step actuation for establishing flow communication between a liquid container containing liquid contents and an initially intact, namely, non-punctured, drug vial. Manual rotation compacts a liquid drug transfer device along a longitudinal device axis for urging a puncturing tip through a drug vial stopper during a drug vial flow communication step for flow communication with a drug vial interior. Manual rotation also executes a liquid container flow communication step for flow communication with a liquid container, therefore establishing flow communication between a drug vial and a liquid container.

Abstract: An adaptor for coupling with a vial having a collar closed by a septum, the septum having an outer surface directed towards the outside of the vial, the adaptor comprising: a gripping member for securing the adaptor to the vial, the gripping member being capable of being laterally mounted on the collar of the vial and a pierceable elastomeric piece having at least a part intended to be in contact with the outer surface of the septum when the adaptor is secured on the vial. Also, an assembly including such an adaptor and a vial.

Abstract: A system and method for intermixing the contents of two containers. The system includes a first container, a second container, and a connector for providing fluid communication between the first and second containers. The connector includes at least one resilient retention member for securing the first container to the connector. In addition, the connector accommodates standard vials containing, for example, medicaments, and prevents the unwanted discharge of the contents of the vial into the environment.

Abstract: The invention provides, in some aspects, a container system for medical solutions such as peritoneal dialysis (PD) solutions. The invention particularly features a system which includes a first compartment that contains a first medical solution, e.g., a PD osmotic agent, and a second compartment that contains a second medical solution, e.g., a PD buffer agent. The compartments maintain their respective contents separately from one another for purposes of transport, storage and/or sterilization. However, the compartments are fluidly couplable, so that their respective contents can be combined with one another, e.g., following sterilization of the agents and prior to their introduction into the patient's abdomen. To that end, a container system can include a diffuser that is disposed in a fluid pathway between the first and second compartments, e.g., to facilitate homogeneous mixing of the first and second PD agents.

Abstract: The invention relates to an insert and a vial for the infusion of a liquid. The vial comprises a hollow body, a grasp portion and a head. The head comprises a delivery opening defining an axis X; a septum for closing the opening; and at least one circumferential push surface next to the head and firmly connected to the grasp portion. The insert is suitable to deliver the liquid and to receive the vial along axis X. The insert comprises a main body with lower ducts, an inner part and a piercing spike. The inner part defines a seat for the vial head, and comprises one slit for engaging the circumferential push surface. The spike is suitable to pierce the vial septum and defines upper ducts. The inner part is able to rotate inside the main body between a fluidly open configuration and a fluidly closed configuration.

Abstract: A drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one syringe adaptor adapted to be attached to a syringe and to the at least one receptacle port adaptor and at least one vial adaptor adapted for connection to a vial containing a drug and adapted for connection to the at least one syringe adaptor, the system being characterized in that at least one of the receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form.

Abstract: The present invention relates to a medical device connector for connecting a piercing device (3), with a vial (2) comprising a base member. A plurality of grip members (50), each grip member (50) comprising a distal end (D) and a proximal end (P) and each comprising a wedge portion (61) adapted to temporarily or permanently lock the medical device connector (1) to the vial (2). The base member (30) further comprises a plurality of flanges (40), wherein the proximal ends (P) of the grip members (50) are arranged to the flanges (41, 40). The flanges (40) extend substantially out from the periphery of the base member (30) in a direction substantially perpendicular to the direction of the grip members, wherein the space formed between the flanges (40) of the base member (30) forms at least one grip portion.

Abstract: A drug mixing system including at least one receptacle port adaptor adapted to be inserted into a port of a fluid receptacle, at least one syringe adaptor adapted to be attached to a syringe and to the at least one receptacle port adaptor and at least one vial adaptor adapted for connection to a vial containing a drug and adapted for connection to the at least one syringe adaptor, the system being characterized in that at least one of the receptacle port adaptor, the at least one syringe adaptor and the at least one vial adaptor being vented to the atmosphere in a manner which prevents release to the atmosphere of possibly harmful contents of the vial in a liquid, solid or gaseous form.

Abstract: A connector device for connecting two containers with first and second members slidably displaceable in regard to each other along an axis between a first and a second position is presented. The first member comprises a needle parallel to the axis so that the first container's septum is penetrated by one end of the needle when the first container is introduced into the first member. The second member comprises a coupling to the second container. The other needle end penetrates the second container's septum when the members are in the second position establishing a connection between the two containers. The first member comprises a coupling to the second container coupled to the second member. The first member can couple to the second container when the two members are in the second position and cannot couple to the second container when the two members are in the first position.

Abstract: In some aspects, a vial spiking device includes a base, a spike extending from the base, and a side wall extending from the base and substantially surrounding the spike. The base and the side wall partially define a recess to receive a portion of a vial. Resilient fingers extend inwardly from the side wall into the recess. The fingers are spaced circumferentially around the side wall and are configured so that as the vial is inserted into the recess, the fingers deflect toward the side wall and allow the portion of the vial to move beyond the fingers. The fingers rebound into the recess after the portion of the vial has moved beyond the fingers. The side wall forces the portion of the vial away from the base and into contact with the fingers after the fingers have rebounded into the recess.

Abstract: A connector is configured to be connected to a syringe assembly provided with at least one syringe having an outer cylinder with a protruding tube-shaped port, and a holder which holds the syringe. The connector includes a connector main body mountable on a container containing a medical solution; a tube-shaped fitting section protruding from the upper section of the connector main body for receiving the syringe to connect the inside of the syringe and the inside of the container when the syringe port is fitted in the fitting section; and fixing means having a lock mechanism that fixes the syringe assembly to the connector main body when the syringe port is fitted in the fitting section, an operating section to release the fixed state provided by the lock mechanism, and a push-out section that pushes out the syringe assembly when the fixing releasing operation is performed.

Abstract: A fluid transfer assembly comprise a first open end for connection to a syringe and a second open end for receiving a vial having a closure element. The second open end is adapted to engage and open the closure element and permit fluid in the vial to be transferred to the syringe from the vial, for example by gravity acting on the fluid in the vial.

Abstract: A transfer system suitable for medicaments comprising a vial socket, a housing having first and second open ends with the first open end being releasably connected to the vial socket, a needle hub mounted within the housing, a needle having first and second piercing ends mounted in the needle hub, a vial having a neck and a body, the vial being inserted in the vial socket and being non removably retained therein, a cartridge having a plunger sealing an open end thereof and a septum located at an opposite end of the cartridge, and an activation cap for causing the needle to penetrate a septum of the vial and the septum of the cartridge to permit transfer of components therebetween.

Abstract: A connection device includes a main holder including a syringe holder to be attached to a syringe and a cannula holder which includes a double-head cannula. The cannula holder is located at a retracted position retracted with respect to the syringe holder in the pre-use state, and is advanced to an advanced position abutting on the syringe holder in the use state. The connection device further includes a separation preventing mechanism which engages the syringe to prevent separation of the syringe from the syringe holder in the state where the cannula holder is located at the retracted position. When the cannula holder is located at the advanced position, the separation preventing mechanism releases an engagement state with the syringe to permit the separation of the syringe from the syringe holder.

Abstract: A connector according to the invention includes a first connection region for connecting a first container, a piercing element and a break-open element, wherein the piercing element has a first end section and a second end section and a channel, running from the first end section to the second end section, for transporting a medicinal active substance, wherein the first end section is formed for piercing a membrane of the first container connected in the first connection region, and, at the second end section, the break-open element is attached such that it can be broken open and/or broken off, wherein, in the attached state, the break-open element seals the channel of the piercing element in liquid tight fashion.

Abstract: To provide a drug solution preparing kit which can be handled with ease in a substantially aseptic manner, and has no risk that a leakage of a drug solution such as a splash and a dispersion of an aerosol to an ambient environment occurs upon preparation of the drug solution There is provided a drug solution preparing kit including a pre-filled syringe and a transfusing tool, wherein the pre-filled syringe includes a sealing member which seals the tip end and can not be removed from the tip end, and that the transfusing tool includes a one-way valve which can discharge only gas from the system in an irreversible manner, and a filter which is provided so as to adjoin to the second communication channel with respect to the one-way valve.

Abstract: The connector for a fluid line of an extracorporeal circuit comprises a tubular body which internally defines a fluid passage, a first connection port predisposed for coupling to the fluid line, a second connection port predisposed for coupling to a male Luer connector borne by an external element, and a closure element of the second connection port. The closure element is formed of a breakable membrane made in a single piece with the tubular body. On coupling, the membrane is broken by the truncoconical projection of the male Luer connector. The connector connects a service line of an extracorporeal circuit to a pressure sensor of a dialysis machine.

Abstract: An automated reservoir filling system for a portable medical device is disclosed. The system includes a vial sealed by a septum partially filled with a liquid and a gas occupying a headspace. The system further includes a reservoir with a volume defined between a reservoir septum and a plunger head. The plunger head is coupled to a plunger arm which is further coupled to a drive system. Further included is a transfer system with a vial end that pierces the vial septum and remains in contact with the liquid, and a reservoir end that pierces the reservoir septum and remains in the reservoir volume. A controller coupled to the drive system to actuates the drive system automatically drawing fluid from the vial to the reservoir through the degas system.

Abstract: A connector assembly includes a first connector having a tubular first connector body, a hollow needle inside the first connector body and a first sealing component piercable by the needle, and a second connector having a tubular second connector body and a second sealing component. The second sealing component is in the second connector body, is attached to a first piercing section when inserted into the first connector body, and, in that state, is pierced by the needle together with the first piercing section. The connector assembly also includes a restriction which, when the second connector is inserted into the first connector, temporarily interrupts and restricts the insertion operation, but allows resumption of such operation when the restriction is removed, and which, when the second connector is withdrawn from the first connector, temporarily interrupts and restricts the withdrawing operation, but allows such operation to resume when the restriction is removed.

Abstract: A system for transferring solutions from a first cartridge into a second cartridge comprises a cartridge holder, a plunger driver, and a cartridge connector. The cartridge connector carries a transfer needle and an exhaust needle. The cartridge holder positions the first cartridge against the cartridge connector so that the transfer needle penetrates the first cartridge septum. The second cartridge is removably inserted into another end of the cartridge connector so that both the transfer needle and the exhaust needle penetrate the second cartridge septum. The plunger driver is disposed to advance a plunger on the first cartridge to transfer solution from the first cartridge into the second cartridge thus displacing solution from the second cartridge through the exhaust needle. The cartridge connector includes a sealed interior waste chamber for receiving the solution from the second cartridge.

Abstract: A double-ended needle and a mixing instrument which are capable of suppressing a reverse flow of a solution are provided. A double-ended needle which constitutes part of a mixing instrument includes a first puncture portion and a second puncture portion having inner cavities thereof communicating with each other, an inner cavity of the first puncture portion and an inner cavity of the second puncture portion communicate with each other, and the lateral cross-sectional area of the inner cavity of the first puncture portion is smaller than the lateral cross-sectional area of the inner cavity of the second puncture portion.

Abstract: A needle protection device detachably fixed to an injection appliance includes a needle, a needle holder from which a needle injection section of the needle projects distally and a needle connection section of the needle projects proximally, a distal needle protection element connected to the needle holder movable in the distal direction from a release position to a protection position and arranged behind the needle injection section in the release position and overlapping the needle injection section and distal end of the injection needle in the protection position, a proximal needle protection element connected to the needle holder movable from a release position and arranged behind the needle connection section into a protection position and overlapping the needle connection section and proximal end of the injection needle, and a blocking device which blocks movement of the proximal needle protection element from the protection position into the release position.

Abstract: A connector is configured to be connected to a syringe assembly provided with at least one syringe having an outer cylinder with a protruding tube-shaped port, and a holder which holds the syringe. The connector includes a connector main body mountable on a container containing a medical solution; a tube-shaped fitting section protruding from the upper section of the connector main body for receiving the syringe to connect the inside of the syringe and the inside of the container when the syringe port is fitted in the fitting section; and fixing means having a lock mechanism that fixes the syringe assembly to the connector main body when the syringe port is fitted in the fitting section, an operating section to release the fixed state provided by the lock mechanism, and a push-out section that pushes out the syringe assembly when the fixing releasing operation is performed.

Abstract: The invention refers to a cartridge (100), such as an injection cartridge, and to a needle system (200) therefore. Further, the invention refers to a combination of such an injection cartridge and a needle system. More specifically, the invention refers to a closure system for an injection cartridge which allows attachment of a needle system to the cartridge.

Abstract: A reconstitution assembly includes a housing including a lower sleeve and an upper sleeve, including a first container and a second container disposed vertically opposite the first container. A transfer set assembly is disposed within the housing between the first container and the second container. The transfer set assembly includes an upper spike housing and a lower spike housing, with a flow path defined through the upper spike housing and the lower spike housing. The transfer set assembly is configured to access contents of the first container and then upon the activation of a triggering mechanism, create a fluid pathway between the first container and the second container. The triggering mechanism includes trigger fingers which ensure the transfer set assembly sequentially accesses the contents of the first container before accessing the contents of the second container. The disposition of the first container activates the triggering mechanism.

Abstract: The present invention relates to a connector device to connect a first and a second fluid container, directly or indirectly. The connector device exhibit a first and a second connection means, a pierceable barrier member, a piercing member, a fluid transfer channel and a pressure normalization channel. The pressure normalization channel is arranged to normalize an increasing pressure inside second fluid container. A valve arrangement permitting fluid to flow in a first and a second direction is arranged in the pressure normalization channel. The valve arrangement exhibit a cracking pressure in at least the first direction. The present invention provides for a connector device which reduces the risk of clogging the barrier filter.

Abstract: A connector is configured to be connected to a syringe assembly provided with at least one syringe having an outer cylinder with a protruding tube-shaped port, and a holder which holds the syringe. The connector includes a connector main body mountable on a container containing a medical solution; a tube-shaped fitting section protruding from the upper section of the connector main body for receiving the syringe to connect the inside of the syringe and the inside of the container when the syringe port is fitted in the fitting section; and fixing means having a lock mechanism that fixes the syringe assembly to the connector main body when the syringe port is fitted in the fitting section, an operating section to release the fixed state provided by the lock mechanism, and a push-out section that pushes out the syringe assembly when the fixing releasing operation is performed.

Abstract: One end of a tubular portion (16) is sealed with a stopcock (5) that is fitted in the tubular portion (16). A first flow channel (33) and a second flow channel (36) are formed in the stopcock (5). A first hole (37), a second hole (43), a third hole (38), and a fourth hole (44) are formed in a connector main body (2). Switching between a setting that brings an inner space (16a) of the tubular portion (16) into communication with the first hole (37) via the first flow channel (33) and a setting that brings the inner space (16a) of the tubular portion (16) into communication with the second hole (43) via the first flow channel (33) and brings the third hole (38) into communication with the fourth hole (44) via the second flow channel (36) can be achieved by rotating the stopcock (5).

Abstract: The present invention relates to a bag (1) for packaging a biological substance, such as animal semen, which is formed by two plastic walls (10, 11) assembled so as to define a pouch (P) for receiving said substance and that comprises a line (15) communicating with said pouch (P) a line for filling the same, this bag comprising in addition at least one pair of openings (3, 4) located on both sides of said line (15), in order to get hung, via these openings, to fingers that are complementary to a supporting device. This bag is characterized in that at least one of these openings (3, 4) has an oblong shape, extends perpendicularly to said line (15), and comprises an area forming a hard spot. The invention relates also to a strip formed by juxtaposing such bags (1), and an assembly comprised of a bag and a hanging support.

Abstract: One end of a tubular portion (16) is sealed with a stopcock (5) that is fitted in the tubular portion (16). A first flow channel (33) and a second flow channel (36) are formed in the stopcock (5). A first hole (37), a second hole (43), a third hole (38), and a fourth hole (44) are formed in a connector main body (2). Switching between a setting that brings an inner space (16a) of the tubular portion (16) into communication with the first hole (37) via the first flow channel (33) and a setting that brings the inner space (16a) of the tubular portion (16) into communication with the second hole (43) via the first flow channel (33) and brings the third hole (38) into communication with the fourth hole (44) via the second flow channel (36) can be achieved by rotating the stopcock (5).

Abstract: A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution.

Abstract: A tubing set is disclosed including a first line having first and second ends, a bag spike at the first end configured for connection to a source of infusate, and a connector at the second end configured for connection to a blood line. The first line has a pumping portion for engagement with an infusate pump. The tubing set includes a second line having first and second ends, the first end being attached to the first line between the first line pumping portion and the first line second end and the second end being configured for connection to the first line between the first line first end and the first line pumping portion. The second line second end is configured for connection to the first line by a dual lumen spike.

Abstract: One end of a tubular portion (16) is sealed with a stopcock (5) that is fitted in the tubular portion (16). A first flow channel (33) and a second flow channel (36) are formed in the stopcock (5). A first hole (37), a second hole (43), a third hole (38), and a fourth hole (44) are formed in a connector main body (2). Switching between a setting that brings an inner space (16a) of the tubular portion (16) into communication with the first hole (37) via the first flow channel (33) and a setting that brings the inner space (16a) of the tubular portion (16) into communication with the second hole (43) via the first flow channel (33) and brings the third hole (38) into communication with the fourth hole (44) via the second flow channel (36) can be achieved by rotating the stopcock (5).

Abstract: A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution.

Abstract: A medicament transport system includes a syringe adapter assembly; and a vial adapter assembly including a base defining an opening having a seal member disposed therewithin, a stem extending from the base and defining a lumen therethrough and an opening through a wall thereof, a needle shuttle valve slidably disposed within the lumen of the stem and supporting a transfer needle and a vacuum needle; and a vacuum cup slidably supported on the stem, wherein a vacuum chamber is defined in the space between the base, the stem and the vacuum cup. The medicament transport system includes a condition where the transfer needle and the vacuum needles penetrate the seal member of the vial adapter assembly, and the vacuum cup is moved to draw a vacuum through the vacuum needle. An automation system is provided that utilizes a medicament transport system for forming a medicament solution from a liquid/non-liquid solution.

Abstract: In certain embodiments, a vial adaptor comprises a housing member, a connector configured to couple the adaptor with a vial, and an extractor channel formed in the housing member. The extractor channel is configured to facilitate withdrawal of fluid from the vial when the adaptor is coupled to the vial. In some embodiments, an anti-reflux valve is positioned within the extractor channel. The anti-reflux valve can be configured to impede or obstruct fluid returning to a fluid source after withdrawal of the fluid from the fluid source.

Abstract: A system for transferring solutions from a first cartridge into a second cartridge comprises a cartridge holder, a plunger driver, and a cartridge connector. The cartridge connector carries a transfer needle and an exhaust needle. The cartridge holder positions the first cartridge against the cartridge connector so that the transfer needle penetrates the first cartridge septum. The second cartridge is removably inserted into another end of the cartridge connector so that both the transfer needle and the exhaust needle penetrate the second cartridge septum. The plunger driver is disposed to advance a plunger on the first cartridge to transfer solution from the first cartridge into the second cartridge thus displacing solution from the second cartridge through the exhaust needle. The cartridge connector includes a sealed interior waste chamber for receiving the solution from the second cartridge.

Abstract: An object is to provide a communicating needle of simple construction which is attached to a medical infusion bag to connect two or more containers in fluid communication with each other. The communicating needle for connecting two or more containers to communicate includes a tip having an outlet opening formed thereon and a seal member integrally formed with the communicating needle to seal the outlet opening. The seal member readily comes off the communicating needle when acted upon by an external force, causing the outlet opening to open. The communicating needle may be covered by a seal body.

Abstract: A mixing apparatus for mixing a first component and a second component comprises: a first vessel which has a negative internal pressure and houses the first component; a second vessel which houses the second component; and a double-ended needle which allows communication between the first vessel and the second vessel when a first stopper element and a second stopper element have been pierced through by the needle. Penetration-resistance increasing parts which have a greater penetration resistance with respect to the first stopper element and the second stopper element than tip end tubes are respectively provided on a first puncture needle and a second puncture needle of the double-ended needle at positions further towards the base end than the tip end tubes. The axial heights of the edge faces of the tip end tubes are both less than the thicknesses of the first stopper element and of the second stopper element.

Abstract: To provide a drug solution preparing kit which can be handled with ease in a substantially aseptic manner, and has no risk that a leakage of a drug solution such as a splash and a dispersion of an aerosol to an ambient environment occurs upon preparation of the drug solution There is provided a drug solution preparing kit including a pre-filled syringe and a transfusing tool, wherein the pre-filled syringe includes a sealing member which seals the tip end and can not be removed from the tip end, and that the transfusing tool includes a one-way valve which can discharge only gas from the system in an irreversible manner, and a filter which is provided so as to adjoin to the second communication channel with respect to the one-way valve.

Abstract: The present invention is a device capable of preventing an operation of establishing communication between a syringe and a vial from being forgotten by error. Holding means constituting a connection device includes: a syringe holding member to be attached to a syringe; a cannula holding member which includes a double-head cannula, is located at a retracted position retracted with respect to the syringe holding member in the pre-use state, and is advanced to an advanced position abutting on the syringe holding member in the use state; and separation preventing means which engages the syringe to prevent separation of the syringe from the syringe holding member in the state where the cannula holding member is located at the retracted position. When the cannula holding member is located at the advanced position, the separation preventing means releases an engagement state with the syringe to permit the separation of the syringe from the syringe holding member.