Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one substrate.

Abstract: A skin cleanser includes a surface, such as a silicone surface, with at least one textured portion for transmitting vibrational tapping to the skin. The skin cleanser includes at least one oscillating motor for generating the tapping motion to the skin. The textured portion includes touch-points or a wave that transmit the tapping motion to skin in contact with the textured portions. The touch-points may include thicker and thinner formations of the touch-points to provide firmer or softer vibrations to the skin. The touch-points are within about 0.5 to 2.5 mm in diameter. One configuration includes multiple oscillating motors configured to provide different vibration frequencies at around 50-300 Hertz and operable simultaneously.

Abstract: Methods of treating patients for conditions such as breast augmentation, soft tissue defects, and urinary incontinence, are described. The methods include removing adipose tissue from a patient, processing a portion of the adipose tissue to obtain a substantially isolated population of cells comprising disaggregated adipose-derived stem cells, mixing the concentrated population of adipose-derived cells comprising disaggregated adipose-derived cells with a portion of unprocessed, intact, non-disaggregated adipose tissue to form a composition, and administering the composition to the patient from which the adipose tissue was removed.

Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.

Abstract: A guide block for an MRI device has a block body with a proximal face, a distal face, and a plurality of passageways extending between the two faces. A first guide passageway within the guide block is open along the body length, extends between the proximal face and the distal face, and is configured to receive a tissue-removing device. A second guide passageway within the guide block is open along the body length, extends between the proximal face and the distal face, and is configured to receive the tissue-removing device. A longitudinal opening extends between the first guide passageway and the second guide passageway, and is coextensive with the first guide passageway and the second guide passageway between the proximal face and the distal face.

Abstract: Tools and methods of use for removing biological units from a body surface utilizing a removal tool are disclosed. The tool incorporates a retention member configured to impede movement of the biological unit in the direction of a distal end of the tool and to improve retention of the biological unit in the tool. The retention member is radially movable within the lumen of the biological unit removal tool. The distal tips of the tools are desirably configured to reduce the chance of transection of a biological unit.

Abstract: Provided herein is an apparatus and method useful for surgical removal of mammalian tissue at specific depths and specific angles. In one or more implementations, an extraction instrument having a main body, a nipple portion, a punch, and an actuator may be utilized to extract one or more hair follicles.

Abstract: The present invention relates to a device and method for cleaning an infant's navel and umbilical cord stump. In particular, the present invention provides a device that eliminates the need for a user to physically hold the umbilical cord stump and allows trapped dirt and moisture to be accessed and removed easily, avoiding premature detachment of the umbilical cord stump and minimizing the risk of infection. The device of the present invention also protects the skin surrounding an infant's navel from cleaning solutions while the infant' navel and umbilical cord stump is being cleaned.

Abstract: Exemplary embodiments of method and apparatus are provided for resurfacing of skin that includes formation of a plurality of small holes, e.g., having widths less than about 1 mm or 0.5 mm. For example, such small holes can be produced using a mechanical apparatus that includes one or more abrading elements provided at the end of one or more rotating shafts, thus avoiding generation of thermal damage as occurs with conventional laser resurfacing procedures and devices. The holes thus formed can be well-tolerated by the skin, and may exhibit shorter healing times and less swelling than conventional resurfacing procedures. The fractional surface coverage of the holes can be between about 0.1 and 0.7, or between about 0.2 and 0.5. The method and apparatus can produce cosmetic improvements in the skin appearance by eliciting a healing response.

Abstract: The apparatus includes at least two skin-contacting elements, the elements having narrow end faces and a mounting assembly for holding the elements closely adjacent to each other. A driving assembly reciprocally moves one element relative to the adjacent element(s) at a frequency that produces an action on the pores of the skin to loosen sebaceous plugs present in the pores, by permitting their ready removal from the skin.

Abstract: A method and corresponding device and kit for treating a human nail may include applying to a surface of said nail distal to the bed of the nail an abrasive surface oscillating through a length in a plane substantially parallel to said nail surface at an area of application and urging the abrasive surface against the area of application with a force substantially normal to the nail surface at the area of application, wherein the urging force taken together with the extent of oscillation of the abrasive surface at the area of application is sufficient to abrade the material of the nail from said surface, but is substantially incapable of damaging living tissues from areas surrounding the nail.

Abstract: The embodiments herein provide a skin polishing apparatus and a method for cleaning and removing a dead skin and dirt from a human body and for polishing a human skin. The apparatus has a skin abrading head provided with a removable brush, which is rotated to remove the dust and to polish the skin. The skin abrading head is mounted with two shower gel tanks filled with a cleansing liquid and a perfume which are sprayed on to the skin to clean and remove the dead skin and the dirt and to polish the skin with a fragrance during a rotation of the head and brush. The apparatus is powered by the rechargeable batteries. The abrading head is rotated with a motor. The rotating speed of the abrading head is controlled with a printed circuit board to a high or low rotating speed.

Abstract: A drive system for controlling movement of an elongate member includes a base unit having a first rotatable knob and a second rotatable knob, a follower assembly including a follower slidably coupled to a guide rail, a longitudinal movement wire, and a rotational movement wire. The follower includes a longitudinal movement pulley, a rotational movement pulley, and an alignment element structured to receive an elongate member such that the elongate member is attachable thereto. The longitudinal movement wire operably couples the first rotatable knob to the longitudinal movement pulley such that rotation of the first knob drives the follower in a longitudinal direction along the guide rail. The rotational movement wire operably couples the second rotatable knob to the rotational movement pulley such that rotation of the second knob rotates the alignment element and attached elongate member.

Abstract: Methods and devices for treatment of damaged tissue are disclosed, including treatment of wounds by employing non-electrically powered, reduced pressure therapy devices with a pressure oscillation mechanism. Maintenance and control of the sub atmospheric pressure exerted may be provided by such devices while minimizing discomfort to the user. The devices may be configured to be worn inconspicuously underneath clothing.

Abstract: The present invention is directed to devices for cleansing, beautifying, and improving the health of skin through exfoliation, brushing, and light therapy. A light therapy device may include a detachable treatment head having a treatment surface. One or more light sources may be located behind the detachable treatment head causing specific wavelengths of light to be emitted through detachable treatment head and/or treatment surface. For example if the treatment surface is comprised of bristles forming a brush, the light may travel inside or along the surface of the bristles. One or more buttons located on the device may be used to activate the light source and select a particular wavelength, such as such as 420 nm for blue or 550 nm for red. A switch may also be used to control the fluency or amount of light energy delivered to the skin.

Abstract: A device, a system employing the device, and method of performing skin treatment are provided for skin treatment. The device includes a vacuum head base defining a chamber therein and having a substantially smooth treatment tip attached and extending from an end thereof or integral therewith. The tip has at least one central opening that is open to the chamber, and is adapted to contact the skin and traverse the skin in a substantially nonabrasive manner. A vacuum access opening is provided through a side wall of the vacuum head base and adapted to connect with a source of vacuum. A tissue stop member is located within the chamber. It may have an abrasive surface for exfoliating skin cells, or a smooth surface for traversing the skin without substantial abrasion.

Abstract: A skin care element holder for use with a handheld body having a receptacle includes a substantially circular plate having a diameter between about 20 and about 60 mm. The substantially circular plate has a first surface for coupling to the skin care element; a second surface; and an outer peripheral edge. The second surface of the substantially circular plate has at least one spacer leg; a plurality of engagement arms; and at least one key. Each of the at least one spacer leg, engagement arms and key extend from the second surface in a direction away from the first surface. The at least one spacer leg supports the plate in the receptacle. At least one of said engagement arms includes a snap-fit projection for engagement with a recess in the receptacle. The key is arranged and configured to fit into a notch in the receptacle.

Abstract: An improved method and apparatus is provided as a system to enhance skin appearance and health, in which skin is cleaned (or exfoliated) and conditioned by use of microelements affixed to a base element or hand-held patch. The dimensions of the microelements are controlled so as to remove a certain number of layers of skin cells and to accumulate those skin cells, along with other foreign substances, into areas between the microelements. In addition, a conditioning compound or therapeutic active can be applied to the exfoliated skin to enhance the skin. Moreover, the amount of accumulated skin cells represents a self-limiting maximum quantity that cannot be substantially exceeded regardless of the number of attempts by a user to re-use the microstructure apparatus. Some of the microstructures are designed with very close-packed microelements, which in some cases have flexible substrates.

Abstract: The present invention provides personal cleaning articles useful for cleaning and/or exfoliating the skin. These articles provide multiple distinct patterns of relatively smooth and coarse elements to provide a user the ability to readily achieve the desired degree of cleansing and/or exfoliation. Further, the article provides a relatively smooth apertured outer layer and a relatively coarse underlying layer whereby a user can, with the application of varied amounts of pressure, more readily achieve and control a wider range of mechanical cleaning and/or exfoliating action against the skin. In certain aspects, the article may also be impregnated with one or more topical skin cleaning and/or exfoliating compounds.

Abstract: Cells present in adipose tissue are used to promote wound healing in a patient. Methods of treating patients include processing adipose tissue to deliver a concentrated amount of regenerative cells obtained from the adipose tissue to a patient. The methods may be practiced in a closed system so that the regenerative cells are not exposed to an external environment prior to being administered to a patient. Accordingly, in a preferred method, cells present in adipose tissue are placed directly into a recipient along with such additives necessary to promote, engender or support a therapeutic benefit.

Abstract: A wound debridement instrument for treatment of chronic wounds has an elongate handle with a distal end, a proximal end, and a middle section. An elongate tubular blade body extends distally from the handle distal end and terminates at a distal cutting edge. The tubular body defines a cavity and has a longitudinal axis. The distal cutting edge follows the arc of the tubular body and is angled relative to the longitudinal axis. In some embodiments the tubular body is an incomplete tube, having a longitudinally-extending gap formed therein. Some embodiments may also have a scraping element extending proximally from the handle proximal end.

Abstract: A method for reducing human or animal tissue includes making a plurality of excisions to collectively form a patch of tissue to be reduced, instead of making a single large excision in the patch. Thus, scarring after healing is less noticeable. The treated regions of tissue may be arranged such that a total area of all removed tissue segments taken in a direction perpendicular to an axis of the patch changes gradually along said axis. The removed regions of tissue may be navicular in shape, and the patches may be navicular in shape in the event an elongated excision is made. The removal of tissue regions can be realized by proper treatment methods such as incisions and laser treatment.

Abstract: A wound therapy device and a kit for same with a housing material, a gasket disposed around at least a portion of the housing material, a non-woven absorption material, and a port. The gasket is sized and configured such that at least a first portion of the gasket will be adhered to a second portion of the gasket upon a folding of the housing material. A method of using a wound therapy device.

Abstract: A tool for use in fixing the position of an implanted item beneath skin, comprises: a main body, a channel in the main body, the channel defining at least two gripping interfaces for engagement with the skin and around the implanted item, wherein the interfaces are positioned such that, when engaged with the skin, the interfaces retain the implanted item in a known position relative to the engaged skin. Methods of using the tool are also described.

Abstract: The invention relates to a test unit for wound drainage coverings comprising: a base body with at least one cavity; at least one supply line that runs through the base body and which connects an outer side of the base body to the cavity; a surface of the base body that is embodied as a support surface for supporting wound coverings and the wound drainage coverings thereof and several channels that run through the base body, the channels connecting the cavities to the support surface. Low pressure can be produced in the cavity and the channels when the support surface is covered in an air-tight manner. As a result, wound drainage applications are tested in different ways using simple and economical means.

Abstract: Exemplary embodiments of method and apparatus are provided for resurfacing of skin that includes formation of a plurality of small holes, e.g., having widths less than about 1 mm or 0.5 mm, using a mechanical apparatus, thus avoiding generation of thermal damage as occurs with conventional laser resurfacing procedures and devices. The holes formed can be well-tolerated by the skin, and can exhibit shorter healing times and less swelling than conventional resurfacing procedures. The apparatus includes one or more needles adapted to remove a small portion of tissue when inserted into and withdrawn from the skin. The fractional surface coverage of the holes can be between about 0.1 and 0.7, or between about 0.2 and 0.5. The exemplary method and apparatus can produce cosmetic effects such as increases in collagen content, epidermal thickness, and dermal/epidermal junction undulations in the skin.

Abstract: A system for treating a skin surface, the system comprising: a base unit comprising: a vacuum source; and a controller; and a treatment device comprising a handle; a treatment head comprising abrading structures with substantially sharp edges for abrading tissue; and a connector to direct negative pressure from the vacuum source to the treatment head.

Abstract: The present invention relates to methods and devices for formation of microconduits in tissue, particularly using an impedance sensing drill to form microconduits. One embodiment of the invention is an impedance sensing drill comprising a drilling assembly, a control module, mechanically connected to the drilling assembly for controlling the depth of drilling by the drilling assembly; and a sensor, electrically connected to the drilling assembly and control module for detecting a change in an electrical impedance of a material being drilled. Another embodiment is a method of forming a microconduit in a material, which comprises the steps of drilling into the material, monitoring an electrical impedance of the material, and stopping the drilling into the material when a change in the impedance is detected, thereby forming microconduit.

Abstract: A skin removal device includes a housing having a handle portion, a drum assembly coupled to the handle portion and including a drum, the drum having an abrasive outer surface configured to abrade skin of a user during rotation of the drum, and an electromechanical drive system disposed at least partially within the housing and configured to rotate the drum. The drum assembly is moveable in a lateral direction relative to the handle portion to enable insertion and removal of the drum assembly.

Abstract: A skin treatment apparatus includes a handle body, a driving unit received in a receiving cavity of the handle body, a treatment head unit, and an inlet arrangement. The treatment head unit includes a supporting member provided at the front end portion of the handle body, a treatment cap detachably attached on the supporting member, a treatment shaft rotatably connected to the driving unit and extended from the driving unit into a treatment cavity, and an abrasion head integrally formed at a free end of the treatment shaft in such a manner that when the treatment shaft is driven to rotate, the abrasion head is also driven to rotate with respect to the handle body. The inlet arrangement is formed at the supporting member of the treatment head unit for providing a predetermined amount of skin treatment fluid in the treatment cavity.

Abstract: An article useful for mechanical skin resurfacing techniques is suitable for transferring mechanical energy from a handheld device to skin placed in contact with the article. The article may be characterized by its Durable Abrasiveness, Compressibility, Displacement, and/or surface roughness. The article may be formed of a fibrous structure having a first major surface having associated therewith an adhesive system and a second major surface, generally opposite the first major surface. The second major surface is arranged and configured to reversibly engage a fastener of a motion-generating unit. The invention also relates to a coupling device for coupling a motorized apparatus to a disposable skin-contactable element. The coupling device includes a water-resistant first attachment and a second attachment for releasably affixing said article to a surface of the motion generation unit.

Abstract: A device and methods for increasing the permeability of the skin's surface to fluid and/or drug delivery is described. The device comprises an abrasive media to remove the outer layer of the stratum corneum, while at the same time applying an electric current that stimulates the skin under the stratum corneum, and delivers fluids from a supply reservoir. The device may also have a vacuum function which evacuates fluid and skin debris from the surface of the skin and delivers the evacuated fluid and skin debris to a waste (or collection) container.

Abstract: The present invention relates to an apparatus for removing dead skin, and more particularly, to an apparatus for removing dead skin which can safely remove hardened skin or dead skin generated on the soles, heels, and palms without damaging normal skin, and simultaneously easily remove the dead skin remaining within the apparatus for removing dead skin. To this end, the apparatus for removing dead skin includes a tube-shaped body on one side of which a blade for removing dead skin is disposed, and a grasping member disposed outside the body.

Abstract: A method for repairing a perforation in a tympanic membrane comprising attaching a single patch to an undersurface of the tympanic membrane covering the perforation.

Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.

Abstract: The present invention relates to a container for anal irrigation. In particular it relates to a rigid container which is easy to operate and which easily is transformed from a storage configuration to a ready-to-use configuration. In one aspect the invention relates to a container for an anal irrigation system. The anal irrigation system comprises an anal probe; a reservoir for holding an irrigation liquid (e.g. water); a pump mechanism for pumping a fluid (e.g. air) into the reservoir; and a liquid tube connecting the reservoir with the anal probe. The container comprises an outer chamber wall, defining at least partly the outer dimensions of the container and an inner chamber wall arranged within the outer chamber wall, said outer chamber wall and inner chamber wall defining the reservoir. This provides a reservoir having a small surface area when filled with irrigation liquid. Thus only a low pressure is necessary to evacuate the irrigation liquid from the reservoir and out through the anal probe.

Abstract: People are constantly tying to perfect their skin. The epidermis is the largest organ in the human body. Many people fill their skin with unnatural products. The Skin Shaver has been invented as a return to grass roots grooming. It removes skin that naturally dies and keeps the skin looking pink and fresh. It is also free of unnatural chemicals.

Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.

Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.

Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.

Abstract: Presented is a simple, novel, process of removing impurities from the scalp, hair, and skin. The process consists of, simultaneously, freezing the impurities with dry, chilled air, freeing the frozen impurities by abrading, and removing the frozen impurities by vacuum suctioning.

Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.

Abstract: A system and method for debriding callus foot tissue is disclosed. The method may include applying a chemical peel to callus foot tissue and using a debriding tool to remove the chemically treated callus foot tissue. In certain embodiment, the method may include preparing the chemical peel, including customizing at least one attribute of the chemical peel based on at least one attribute of the callus foot tissue. The system may include a debriding tool having a cutting head that may be easily removed for cleaning or replacement.

Abstract: The present invention generally relates to devices for harvesting a skin graft(s). The present invention provides a blister raising device integrated with a member for cutting the blister.

Abstract: A hand held exfoliation device suitable for repeated use on a facial skin surface is provided. The exfoliation device includes a body and an exfoliating material attached thereto that is sized for application to a facial skin surface. The exfoliating material includes a substrate and an exfoliating surface. The exfoliating surface is formed from a plurality of particles, wherein the plurality of particles are attached to the substrate to form peaks and valleys thereon. The exfoliating material has a surface roughness Sa from about 2 ?m to about 16 ?m and the particles have an average Mohs hardness from about 4 to about 8.

Abstract: A skin removal instrument that comprises first and second resilient arms. Each of the first and second arms includes a main body that has a middle, an attachment end and a nipping end opposite the attachment end. The attachment ends are attached to one another, thereby forming a spring area that allows the nipping ends to resiliently move toward and away from each other. Each of the first and second arms includes an outer gripping area disposed offset from the middle of the main body of the first and second arms, respectively. The outer gripping area has a substantially bulbous shape. Each of the nipping ends of the first and second arms includes an extension portion that extends from the main body and a nipping blade portion that extends from the extension portion. Each of the nipping blade portions has an angled surface angled downwardly from an inner surface of the extension portions, respectively, such that the nipping blade portions converge toward one another.

Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.

Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.

Abstract: A skin removal device includes a housing having a handle portion, a drum assembly coupled to the handle portion and including a drum, the drum having an abrasive outer surface configured to abrade skin of a user during rotation of the drum, and an electromechanical drive system disposed at least partially within the housing and configured to rotate the drum. The drum assembly is moveable in a lateral direction relative to the handle portion to enable insertion and removal of the drum assembly.

Abstract: Certain embodiments disclosed herein relate to compositions, methods, devices, systems, and products regarding frozen particles. In certain embodiments, the frozen particles include materials at low temperatures. In certain embodiments, the frozen particles provide vehicles for delivery of particular agents. In certain embodiments, the frozen particles are administered to at least one biological tissue.