Abstract: Guided ablation instruments are disclosed for creating lesions in tissue, especially cardiac tissue for treatment of arrhythmias, including atrial fibrillation. In one aspect of the invention, a percutaneous catheter is disclosed with an endoscope positionable in the instrument's distal end region to obtain an image. The image allows the clinician to determine whether contact has been achieved (or blood has been cleared from an ablative energy transmission path) before ablation begins or while ablation is occurring. In one embodiment, percutaneous ablation catheters are disclosed having at least one central lumen and one or more balloon structures at the distal end region of the instrument. Also disposed in the distal end region are an illuminating light source and an endoscope capable of collecting sufficient light to relay an image to the user. The instruments can further include an ablation element.

Abstract: A method and apparatus for performing ophthalmic laser surgery using a pulsed laser beam is provided. The method includes establishing an initial cutting pattern comprising a plurality of original photodisruption points, establishing an enhanced cutting pattern comprising a plurality of enhanced photodisruption points selected to decrease potential adverse effects due to patient movement and having increased density over a fixed area as compared with the plurality of original photodisruption points, and performing an ocular surgical procedure according to the enhanced cutting pattern. Enhanced cutting patterns may include circular cuts around the periphery of a capsule, vertical side cuts for lens fragmentation, raster lamellar cuts, and grid lamellar cuts. Each photodisruption point in the initial cutting pattern and the enhanced cutting pattern comprises a laser target point.

Abstract: A Laser therapy device that uses temperature sensing to provide clinical feedback and optical elements to produce a projection pattern for a given therapeutic application. Integrated thermal imaging provides the operator with visual representation of the tissue being treated. The optical elements are contained in a replaceable lens assembly that also contains an electronic identification chip to allow the device to automatically reconfigure behavior according to the type of lens. The device includes a wireless data transceiver that can be used for remote configuration and control. The device has the ability to modulate the output power over a wide range using a combination of pulse width modulation (PWM) and analog control techniques. The device provides on-demand audio-visual training.

Abstract: A vaso-occlusive device delivery assembly includes a pusher assembly having proximal and distal ends, a conductive sacrificial link disposed at the distal end of the pusher assembly, and a vaso-occlusive device secured to the pusher assembly by the sacrificial link. The pusher assembly includes first and second conductors extending between the proximal and distal ends thereof. The sacrificial link is electrically coupled between the first and second conductors, such that the first conductor, sacrificial link and second conductor form an electrical circuit, and, when a disintegration current is applied through the sacrificial link through the first and second conductors, the sacrificial link thermally disintegrates, thereby releasing the attachment member and vaso-occlusive device from the pusher assembly.

Abstract: A system is described for removing heat from a subject's subcutaneous lipid-rich regions, such as tissues, organs, cells, and so forth. In various embodiments, the system includes a controller, a computing device, a data acquisition device, a chiller, and one or more applicators. The system can employ these components to receive a selection of a treatment profile and apply the selected treatment using an applicator. The treatment profile may be received from a patient protection device that connects to an applicator.

Abstract: Systems and processes are described relating to laser-based ophthalmic intervention technologies and, more specifically, to techniques for delivering reproducible amounts of laser energy to create visible and sub-visible lesions on an eye. The subject technology may provide a user with the ability to adjust the amount of energy to be delivered to the eye tissue by selecting a single numerical value. In response, the system may adjust the power and/or duration of the laser treatment beam pulse according to an operating curve determined by the system.

Abstract: Disclosed is an applicator or handpiece configured to apply treatment energy to a segment of skin located in a tissue or skin treatment plane. The treatment energy could be RF energy, applied by a pair of bipolar RF electrodes or optical energy. The applicator includes an optical system configured to form a rectangular spot and homogenize the optical energy distribution.

Abstract: According to a measuring method or a control method of life activity, a life object is illuminated with an electromagnetic wave including a wavelength in a designated waveband, and a characteristic in a local area of the life object is detected, or a life activity thereof is controlled. The “designated waveband” is defined based on phenomena used for detecting or controlling an activity state of the life object or a change of the state. This “local area” is an area constituted by one or more cells.

Abstract: A bone fixation system is provided. The bone fixation system may include a plate, one or more fasteners configured to attach the plate to a target anatomical location such as bone, and a surgical device that facilitates the attachment of the plate and the fasteners.

Abstract: Methods and systems are provided for delivering visible or infrared biostimulatory energy to bone marrow to subjects having or developing Alzheimer's disease. The radiation is delivered to sites remote from the brain at a dose sufficient to cause stimulated mesenchymal stem cells to appear in the brain and degrade ?-amyloid. The energy may be coherent light and can be administered transcutaneously, subcutaneously, or via an intramedullary probe.

Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, an auto-fixing actuation control, a flexible housing tube having a flexible housing tube distal end and a flexible housing tube proximal end, a first flexible housing tube portion having a first stiffness, and an optic fiber disposed within an inner bore of the handle and the flexible housing tube. An actuation of the auto-fixing actuation control may gradually curve the flexible housing tube. A gradual curving of the flexible housing tube may gradually curve the optic fiber.

Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, an actuation control of the handle, a flexible housing tube having a flexible housing tube distal end and a flexible housing tube proximal end, an optic fiber disposed within an inner portion of the handle and the flexible housing tube, and a cable disposed within the flexible housing tube and the actuation control. A rotation of the actuation control may be configured to gradually curve the flexible housing tube and the optic fiber. A rotation of the actuation control may be configured to gradually straighten the flexible housing tube and the optic fiber.

Abstract: A laser device having a proximal end and a distal end spaced from the proximal end, the distal end configured to receive a fixation member to be affixed to a target surgical site. The laser device includes a laser source supported by the laser device body and capable of emitting a laser beam to the distal end, wherein the laser source is responsive to at least one input so as to selectively switch between an inactive configuration whereby the laser source does not emit the laser beam, and an active configuration whereby the laser source emits the laser beam.

Abstract: A bone fixation system is provided. The bone fixation system may include a plate, one or more fasteners configured to attach the plate to a target anatomical location such as bone, and a surgical device that facilitates the attachment of the plate and the fasteners.

Abstract: A steerable laser probe may include an actuation structure, a nosecone fixed to the actuation structure by one or more links and one or more link pins, a flexible housing tube, and an optic fiber disposed in the flexible housing tube and the actuation structure. A compression of the actuation structure may be configured to gradually curve the flexible housing tube and the optic fiber. A decompression of the actuation structure may be configured to gradually straighten the flexible housing tube and the optic fiber.

Abstract: A steerable laser probe may include a handle having a handle distal end and a handle proximal end, an actuation control of the handle, a flexible housing tube having a flexible housing tube distal end and a flexible housing tube proximal end, an optic fiber disposed within an inner portion of the handle and the flexible housing tube, and a cable disposed within the flexible housing tube and the actuation control. A rotation of the actuation control may be configured to gradually curve the flexible housing tube and the optic fiber. A rotation of the actuation control may be configured to gradually straighten the flexible housing tube and the optic fiber.

Abstract: A bone fixation system is provided. The bone fixation system may include a plate, one or more fasteners configured to attach the plate to a target anatomical location such as bone, and a surgical device that facilitates the attachment of the plate and the fasteners.

Abstract: An optical coherence tomography probe and laser combination device configured for real-time z-directional guidance of the incisional depth of a surgical procedure. It can be used alone or placed within the working channel of an endoscope. The device includes an OCT single mode fiber, and a laser fiber or laser hollow waveguide or electrical surgical wire positioned adjacent to the OCT single mode fiber. The single mode fiber is configured to move laterally when activated by an actuator to scan light data reflected from a sample that is positioned in front of a distal end of the device. The light data can be processed to generate a B-scan image. The device can collect data in real-time during lasing, or immediately prior to and following the cutting. The surgical tool, when coupled to a processor, can deactivate when the B-scan image identifies that the incision is within a predefined tolerance.

Abstract: System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities. The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a nerve bundle, or the surface of the heart. Such direct, conformal contact increases accuracy of measurement and delivery of therapy.

Abstract: An optical surgical probe includes a handpiece having a metal cannula at a distal end, a light guide within the metal cannula that carries a light beam from a light source through the metal cannula, and a multi-spot generator formed within a distal opening of the metal cannula that seals the distal opening of the metal cannula. The multi-spot generator includes a proximally-facing faceted end surface spaced from a distal end of the light guide that includes at least one facet oblique to a path of the light beam and a ball lens located distal to the faceted end surface. A high-conductivity ferrule surrounds the distal end of the light guide, is in thermal contact with the metal cannula, and includes a side-shield portion extending beyond the distal end of the light guide. The ferrule shields the cannula from a portion of the light beam reflected by the faceted end surface.

Abstract: A treatment apparatus comprising a handpiece, the handpiece having a primary treatment element and a contact surface, at least one electrode located at the contact surface, and a connection element to connect the at least one electrode to a controller to provide analgesia.

Abstract: A stone capture device comprises a shaft with a deployable sweeping structure at its distal end. The shaft is adapted to be removably placed over and connected to a conventional ureteroscope. The combination of the stone capture device and ureteroscope can be introduced into the urinary tract to capture, fragment, and remove stones from the bladder and kidney.

Abstract: Various embodiments are directed to battery unit for use with surgical instruments. The battery units may comprise a plurality of cells and include a translatable discharge drain. When attached to the surgical instrument, the discharge drain may electrically connect an anode of the battery unit to a cathode of the battery unit, for example, via a resistive element in order to drain the battery unit.

Abstract: An apparatus that will alter the fibrous strands in the fatty layers of the skin to reduce the appearance of cellulite and adipose tissue. Electromagnetic energy is used to selectively shrink or alternatively photoacoustically ablate the collagen in the constricting bands of connective tissue that causes the dimpled appearance of cellulite and adipose tissue while avoiding damage to the surrounding fatty cells.

Abstract: A particle includes a ferromagnetic material, a radiopaque material, and/or an MRI-visible material.

Abstract: The inventive ablation element comprises an elongated cannula having a proximal end and a distal end. The cannula defines an internal lumen and a cannula axis. A plurality of conductors contained within the lumen, each having a proximal end proximate the proximal end of the cannula, and a distal end proximate the distal end of the cannula. A plurality of ablation stylets each has a proximal end and a distal end, and each coupled to the distal end of a respective conductor, the conductors together with their respective stylets being mounted for axial movement. A trocar point defined proximate the distal end of the cannula. A deflection surface positioned between the trocar point and the proximal end of the cannula, the deflection surface being configured and positioned to deflect at least some of the stylets laterally with respect to the cannula axis in different directions defining an ablation volume.

Abstract: Disclosed are apparatus, method, devices and instruments, including an apparatus that includes a flexible waveguide coupled to a supporting structure, and further coupled to a treatment tip. The apparatus also includes a beam controller to control application of a radiation beam emitted from the flexible waveguide to distribute the beam over an area different than an area covered by direct application of the beam to a single location on a target tissue. Further disclosed is an apparatus that includes a waveguide, coupleable to a laser source, and a thermal protection instrument. The thermal protection instrument includes a tissue contacting member to contact a part of an area of a tissue irradiated by laser radiation, and a beam blocking element to absorb at least some of radiation not absorbed by the area of the tissue, the beam blocking element being thermally isolated from the area of the tissue.

Abstract: An improved procedure for performing liposuction is obtained by utilizing a needle that includes a laser source conductor with one end of the needle being configured for insertion into a target adipose skin volume and the other end being coupled to a laser source. The needle may include one or more channels for extracting the treated adipose area. A vacuum source can be used in the extraction of the treated adipose. Further, the first end of the needle may include a cap or end-piece that reduces the build up of carbon deposits. A temperature sensor may be used as input to adjust the laser power and prevent over exposure.

Abstract: A noninvasive method of reducing fat from targeted regions of a patient's body by applying low-level laser energy externally through the skin of the patient to the targeted areas. Sufficient laser energy is applied to release at least a portion of intracellular fat into the interstitial space. The released intracellular fat is removed from the body through the body's natural functions. The preferred embodiment uses laser energy at about 635 nm.

Abstract: An interstitial laser energy treatment apparatus having co-acting movable probe holders which facilitate positioning of a laser probe and thermal probe in different positions relative to a tissue mass such as the tumor to be treated and relative to each other to facilitate treating tissue masses based on the exact position, size and shape of the tissue mass.

Abstract: The various embodiments of the present inventions provide stabilization devices and methods for use of the stabilization devices with minimally invasive gynecological procedures such as methods of preventing pregnancy by inserting intrafallopian contraceptive devices into the fallopian tubes.

Abstract: An integral laser imaging and coagulation apparatus, and associated systems and methods that allow an ophthalmologist to perform laser retinal surgical procedures with an integral laser imaging and coagulation apparatus disposed at a first (i.e. local) location from a control system disposed at a second (i.e. remote) location, e.g., a physician's office. In some embodiments, communication between the integral laser imaging and coagulation apparatus and control system is achieved via the Internet®.

Abstract: A method for puncturing a pericardial membrane of a human patient, the method comprising inserting a needle into the chest of the human patient, detecting a phase of a mechanical activity of the heart of the human patient, advancing the needle toward the heart of the human patient in synchronization with the detected phase of the mechanical activity of the heart of the human patient, and repeating the detecting and advancing steps until the pericardial membrane of the human patient is punctured.

Abstract: A system and device for treating a target tissue is provided herein. The treating device and system is based on a fractional treatment of an incision edge prior to closure of the incision to prevent scar formation.

Abstract: An optical radiation delivery structure including a waveguide conduit having a surgical access portion and a handle portion. The handle portion includes a gripping portion and a waveguide lock, which is configured to have only a locked state and an unlocked state. In some embodiments, the handle portion includes a gripping portion and a counterbalance region, such that a center of mass of the waveguide conduit is disposed towards a proximal end of the waveguide conduit.

Abstract: A forceps includes an end effector assembly having first and second jaw members movable relative to one another between a spaced-apart position, a first approximated position, and a second approximated position. One or both of the jaw members including a first stop member coupled thereto and disposed between the jaw members. The first stop member is longitudinally translatable along a surface of the at least one jaw member from a first position, wherein the first stop member inhibits approximation of the jaw members beyond the first approximated position, and a second position, wherein the first stop member inhibits approximation of the jaw members beyond the second approximated position.

Abstract: System, devices and methods are presented that integrate stretchable or flexible circuitry, including arrays of active devices for enhanced sensing, diagnostic, and therapeutic capabilities. The invention enables conformal sensing contact with tissues of interest, such as the inner wall of a lumen, a the brain, or the surface of the heart. Such direct, conformal contact increases accuracy of measurement and delivery of therapy. Further, the invention enables the incorporation of both sensing and therapeutic devices on the same substrate allowing for faster treatment of diseased tissue and fewer devices to perform the same procedure.

Abstract: Skin cooling apparatus is provided for use with a medical treatment device such as a hypodermic syringe or a skin ablation laser or other electromagnetic source. The skin cooling apparatus provides selective, localized cooling of the target area that is acted upon by the medical treatment device. Included is a support body engaging at least a portion of the medical treatment device, for supporting and orienting the medical treatment device to the target area. A solid state cooling device such as a thermoelectric or Peltier device is carried by the support body and includes a cooling surface facing the target area of a patient's skin surface. The support body may be flexible so as to allow the medical treatment device to be inclined relative to the skin surface. The support body may also include aiming structure for directing the medical treatment device to a particular point within the target area.

Abstract: A probe detachably connected to an optical measurement apparatus includes: a fiber that emits light by the optical measurement apparatus, and outputs reflected light and/or scattered light from an object to be measured; a covering member that covers a side face of the fiber; a cap that covers a distal end of the probe; a standard object that is provided on a surface of the cap facing the distal end of the fiber and that is used in calibration measurement by light emitted from the distal end of the fiber; an adhesive member that adheres the cap to the distal end of the probe and is made of an adhesive material; a heat-generating portion that generates heat to be applied to the adhesive member; and a thermal conduction portion that conducts heat that decreases the adhesive strength of the adhesive material with respect to the covering member.

Abstract: A smoke evacuation attachment device for attachment to a laser resurfacing handpiece that includes a channel for evacuating smoke, dead skin cells, and other debris from the application site of the laser and which has a low profile to preclude encumbering the use of the laser handpiece.

Abstract: A radiation treatment bra is disclosed. In the illustrative embodiment, the bra includes adjustable elements and a medial window. During radiation treatment planning, the elements are adjusted to establish a reference breast geometry. The reference breast geometry is reproduced prior to an actual treatment session by repeating the original adjustment of the elements, as necessary. The medial window enables a light field to be projected onto the patient's chest, and read therefrom, thereby establishing proper alignment of the patient to the radiation treatment machine.

Abstract: Methods for decreasing the size and/or changing the shape of pelvic tissues. Energy, preferably radio frequency or laser energy, may be applied to endopelvic fascia or other subcutaneous tissue transcutaneously, through one or more incisions in skin, or directly to the desired subcutaneous tissue after a strip of mucosa or skin has been removed. Such an application of energy may cause the subcutaneous tissue to shrink, thereby bringing the mucosa or skin edges closer together while minimizing damage to deep nerves and other surrounding tissues. Such manipulation of the layers of the skin may be utilized to decrease the size or change the shape of numerous anatomical structures and may also serve to alleviate the symptoms of urinary incontinence, dyspareunia, or chronic pelvic pain. The method steps of the present invention may further provide for the beneficial pretreatment of a tissue site prior to stem cell implantation.

Abstract: The laser applicator includes a catheter (10) having a proximal section (10a), a midsection (10b) and a distal end section (10c). It contains a light guide, the light of which is output in a decoupling portion (40). The light guide runs in a longitudinal groove on the outside of a catheter body. While the light guide (20) is continuous, the catheter is composed of catheter bodies, which are joined together at a catheter splice site (37).

Abstract: The invention relates to a laser catheter for bypass surgery. The laser catheter comprises: a tubular arrangement comprising a tubular bundle of optical fibres having distal ends defining an emitting surface for emitting laser radiation in the distal direction of the catheter; at the distal end of the catheter, a channel extending in axial direction of the catheter and defined by the inside of the tubular arrangement, which channel is connectable to a suction source; and a grid element arranged inside the channel at a distance proximally from the emitting surface, which grid extends in transverse direction of the catheter across the channel. The laser catheter further comprises a narrowing arranged inside the channel and, viewed in axial direction of the catheter, between the emitting surface and the grid.

Abstract: A sensor for detecting the presence of skin is disclosed, one configuration of which uses multiple light emitting diodes, each of a unique wavelength band, and a broad-band photodetector to measure the remission of light at multiple wavelengths from a material being analyzed. Characteristics of the spectral remission of the material are used to discriminate human skin from materials that are not human skin. Further, an aesthetic medical device utilizing such a sensor in which the device is inhibited from operation if skin has not been detected. The incorporation of a skin sensor improves the safety of devices that emit radiation that otherwise would pose a hazard if not directed onto skin.

Abstract: A cold plasma device having a broad surface of plasma generation allowing for the efficient treatment of larger areas with the benefit of being durable, portable and able to treat almost any anatomical structure. The cold plasma device has a constant radius surface, which creates a tangential surface with an infinite number of distances between the surface edge of the substrate under treatment and the device.

Abstract: A satellite platform facilitates the dividing of a laser system into functional modules, and operates to provide one or more of the functional modules directly into (e.g., closer toward) a user's operational space. In a typical implementation, the satellite platform pairs two or more of the functional modules into a combination and places it in the user's operational space. The two or more functional modules can be two of the major components of the laser-system user interface, namely, the handpiece and the control panel. The combination is provided by way of the satellite platform directly into the user's operational space, while part, all, or a majority of, the laser system may remain away from the use's operational space (e.g., on the wall, on the counter-top or at the walk-way). A particular embodiment of the satellite platform takes the form of an articulated arm similar to that used for components in conventional dental chairs.

Abstract: An apparatus and a method are described for setting up a medical laser machine configured to be used in eye surgery for making a multi-planar incision. In various embodiments, a software interface is provided to receive, from a user, one or more dimensional measurements of an eye of a patient as input, automatically calculate precise geometric and other setup parameters, based on a set of equations, of a multi-planar incision for the patient's eye, and provide the calculated parameters to the user for setting up the medical laser machine to make the incision.

Abstract: A laser device (10) for ablating a biological tissue (1), comprising: a) a laser source (7) that is configured to emit a laser beam (4); b) optics (8a, 8b, 8x) configured to modify the laser beam (4) such as to direct the laser beam (4) on the biological tissue (1); d) a controller (11) that is configured to control the laser source (7) to emit the laser beam (4) to create an ablation in biological tissue (1), whereby e) a sensor (19) being configured to receive back scattered light from the biological tissue (1); f) a tissue controller (18) that is operationally coupled to the sensor (19) to receive a sensor signal (Ri) of the sensor (19); and g) the tissue controller (18) being configured to compare a series of at least two consecutive sensor signals (R1, R2, R3, . . . ) and being configured to generate a tissue control signal (TCS) when the value of the series of consecutive sensor signals (R1, R2, R3, . . . ) decreases in a predetermined amount.

Abstract: A dermatological skin treatment device is provided. The device comprises a handpiece and a cutting tool, wherein the tool is inserted through the conduit and percutaneously inserted into a tissue disposed within a recessed area of the handpiece. The device and method cut the fibrous structures under the skin that cause cellulite at an angle substantially parallel to the surface of the skin and replace these structures with a non-cellulite forming structure by deploying a highly fibrous mesh through a single needle hole to create a highly fibrous layer directly or through wound healing processes.