Abstract: An interstitial laser energy treatment apparatus having co-acting movable probe holders which facilitate positioning of a laser probe and thermal probe in different positions relative to a tissue mass such as the tumor to be treated and relative to each other to facilitate treating tissue masses based on the exact position, size and shape of the tissue mass.

Abstract: Optical ear infection treatment device and methods are described where an LED and optical light pipe are used to deliver the light from the LED to the middle ear of a patient to reduce bacterial growth and/or eliminate bacteria. Typically, the device is placed in the ear and then activated by the user by pressing an activation button. Once activated the control electronics will turn on the LED and perform a treatment. The most basic treatment mode comprises turning on the LED at maximum power for a predetermined period, e.g. 30 minutes, 60 minutes. When the preset duration is completed, the device will notify the user by an audible beep or vibration that the treatment is complete. Once completed the user can remove the device, the treatment could be repeated once a day or for extreme cases multiple times during the day.

Abstract: Fourth toe processing apparatus and methods for the processing the fourth toes of a bird are disclosed.

Abstract: An ophthalmic surgery illuminated directional laser probe has a handle and a rigid tubular tip projecting from the handle, and has an illumination optic fiber and a laser optic fiber that extend through the handle and the tip. A mechanism on the handle is operable to extend distal ends of the illumination optic fiber and the laser optic fiber from the distal end of the instrument tip, and to retract the distal ends of the illumination optic fiber and the laser optic fiber back into the interior of the tip. At least one of the distal ends of the illumination optic fiber and the laser optic fiber is held in a curved configuration. The distal ends of the illumination optic fiber and the laser optic fiber are secured to each other, whereby both the illumination optic fiber and the laser optic fiber curve into a bent configuration as the distal ends of the illumination optic fiber and the laser optic fiber are extended from the distal end of the instrument tip.

Abstract: Skin cooling apparatus is provided for use with a medical treatment device such as a hypodermic syringe or a skin ablation laser or other electromagnetic source. The skin cooling apparatus provides selective, localized cooling of the target area that is acted upon by the medical treatment device. Included is a support body engaging at least a portion of the medical treatment device, for supporting and orienting the medical treatment device to the target area. A solid state cooling device such as a thermoelectric or Peltier device is carried by the support body and includes a cooling surface facing the target area of a patient's skin surface. The support body may be flexible so as to allow the medical treatment device to be inclined relative to the skin surface. The support body may also include aiming structure for directing the medical treatment device to a particular point within the target area.

Abstract: A nipple protector is provided, which is able to protect a nipple of a user reliably, by protecting the nipple area so as to maintain a non-contact state with the nipple area and thereby avoiding the causing of pain or unpleasant irritation to the nipple area, as well as avoiding the leaving of marks while reducing irritation when abutted against the breast. A nipple protector having a hard outer member or shell and an inner member made of a material which is more flexible and deformable than the outer member, with an internal space being formed inside the nipple protector, wherein the internal space is formed by a cylindrical portion which extends from the outer member and/or the inner member, and the inner member has an abutting section which surrounds with no gap the nipple area of a wearer completely, and the abutting section is a deformable abutting section which deforms elastically and is capable of making contact, with no gap, with the perimeter of the nipple area.

Abstract: A light transmission system to provide photodynamic treatment to a patient includes a single use integrated control module and catheter assembly having a plurality of light emitting diodes (LEDs) to transmit light toward target cells within a patient. The integrated light catheter and control module are used in combination with a light activated drug. Selected operating parameters may be programmed into the control module, or it may be wirelessly programmable in situ prior to use to allow user flexibility to tailor treatment for a particular patient or condition. Among the features that prevent reuse are that the control module lacks access to recharge the power source, and it may include a deactivation module that destroys circuitry or software when triggered. To prevent patient interference when in use, the control module may also be configured to selectively deactivate.

Abstract: Multi-directional deflectable catheter apparatuses, systems, and methods for achieving renal neuromodulation by intravascular access are disclosed herein. One aspect of the present application, for example, is directed to apparatuses, systems, and methods that incorporate a catheter treatment device comprising an elongated shaft. The elongated shaft is sized and configured to deliver a thermal element to a renal artery via an intravascular path. Thermally or electrical renal neuromodulation may be achieved via direct and/or via indirect application of thermal and/or electrical energy to heat or cool, or otherwise electrically modulate, neural fibers that contribute to renal function, or of vascular structures that feed or perfuse the neural fibers.

Abstract: In a method, a device and an apparatus system for therapy of prostate cancer, in the course of a therapy session the prostate of a patient is subjected at different locations to a diagnostic examination with regard to the presence of a tumor, and in the case of a positive diagnosis the prostate is therapeutically treated at the corresponding location during the therapy session. The device has a hollow needle, a biopsy needle carrying an extraction element at its forward end that serves to extract a tissue sample, and a therapy element serving to therapeutically act at a location of the prostate. The biopsy needle or the optical waveguide and the therapy element are designed so that they can be inserted into the hollow needle. The apparatus system includes a diagnostic unit and a therapy unit for focal therapy treatment of the prostate, the diagnostic unit including a device for histological assessment of prostate tissue.

Abstract: Acupuncture device uses a laser beam. Acupuncture device is configured for bringing about a suitable treatment relevant to the pain in a patient and so that it is adapted to all aspects of practice, in particular so as to enable easy replacement of laser diodes of different intensity levels or laser modules of different wavelengths and a lasting operating capacity of all its elements. Therefore, the acupuncture device includes the following elements: a control apparatus including several outlets for electrical conductors; several electrical conductors connected to the outlets of the control apparatus; several laser diodes connected to the electrical conductors; and several laser needles which are connected to the laser diodes, so that the laser beam emitted by the laser diodes is injected into the laser needles, and which are designed to contact, through their output region, a patient's body. Device may be used to irradiate blood.

Abstract: Exemplary embodiments of the present disclosure provide method and apparatus for facilitating stretching of a bio-logical tissue by forming a plurality of micro-slits in the tissue. Each micro-slit can be less than about 2 mm or less than about 1.5 mm long, or even less than about 1 mm, such that small gaps that can heal quickly can be formed when the tissue is stretched. The micro-slits can be formed using a plurality of cutting arrangements or an ablative laser. The micro-slits can be formed in various patterns, including staggered rows, circular or spiral patterns, or random patterns.

Abstract: A bone fixation system is provided. The bone fixation system may include a plate, one or more fasteners configured to attach the plate to a target anatomical location such as bone, and a surgical device that facilitates the attachment of the plate and the fasteners.

Abstract: An endoprobe for ophthalmic microsurgery for intraocular treatment of the eye and that affords a surgeon good visibility regardless of the distance from the treatment site in the eye. The endoprobe includes a stainless steel cannula enclosing one or more optical fibers and a laser fiber. A distal end of the optical fibers can be closed by a transparent lens-shaped structure such that an illuminating light transmitted through the optical fibers is radiated and transmitted laser light can exit from the laser fiber, or such that the laser fiber is embedded in a transparent shaped element. The laser fiber may have a covering for transporting light. The laser light may be injected directly into the laser fiber and the illuminating light is injected via at least one optical element into the covering of the laser fiber or into the transparent shaped element.

Abstract: The present invention provides a method of laser processing of materials, specifically laser induced ablation processes for laser removal of material particularly important in medical and dental applications in which the laser removal of material should be done in such a way as to not damage any of the surrounding soft or hard biomaterial. The ablation process is achieved by impulsive heat deposition (IHD) by direct and specific excitation of short lived vibrations or phonons of the material in such a way as to not generate highly reactive and damaging ions through multiphoton absorption. The heat deposition and ensuing ablation process under prescribed time and wavelength conditions for laser irradiation is achieved faster than heat transfer to surrounding tissue by either acoustic or thermal expansion or thermal diffusion that otherwise would lead to excess heat related damage.

Abstract: Device and method for lasering biological tissue. In a general aspect, the device for lasering a biological tissue may include a source configured to provide a pulsed laser beam, an outcoupler configured to couple the laser beam towards the tissue, and an outfeeder configured to feed a photosensitizer in a direction of the tissue where the outfeeder is connected to the outcoupler. In another general aspect, a method for lasering a biological tissue may include applying a photosensitizer towards the tissue, providing a pulsed laser beam, and lasering a site of the tissue with the pulsed laser beam where the laser beam is emitted with a temporal width at a half maximum range from about 1 ps to about 100 ps.

Abstract: The laser applicator includes a catheter (10) having a proximal section (10a), a midsection (10b) and a distal end section (10c). It contains a light guide, the light of which is output in a decoupling portion (40). The light guide runs in a longitudinal groove on the outside of a catheter body. While the light guide (20) is continuous, the catheter is composed of catheter bodies, which are joined together at a catheter splice site (37).

Abstract: The present invention provides and a laser focused ablation apparatus and method of use configured to ablate a cement mantle surrounding a stem of a hip prosthesis, for use during a revision arthroplasty. The apparatus comprises a laser generation system generating a laser light and a handpiece to receive the laser light. The handpiece includes an elongated main conduit terminating at a laser emission tip, the laser emission tip providing a tip and a curvature disposed between the tip and the elongated main conduit such that the laser light exits the tip at a direction oblique to a longitudinal axis of the elongated main conduit.

Abstract: A light energy delivery head is provided which, in one aspect, mounts laser diode bars or other light energy emitters in a heat sink block which is adapted to cool both the emitters and a surface of a medium with which the head is in contact and to which it is applying light energy. In another aspect, various retroreflection configurations are provided which optimize retroreflection of back-scattered light energy from the medium. The size of the aperture through which light energy is applied to the medium is also controlled so as to provide a desired amplification coefficient as a result of retroreflection.

Abstract: A hand-held self-contained nerve-stimulation device and method using light to provide a source of precise stimulation on one or more nerve fibers. In some embodiments, this simulation is provided through a device and method wherein a laser- or LED-light source is mounted to the handpiece. Light is passed from the light source through optical tip to simulate nerves. In some embodiments, the device is constructed from non-magnetic material such as glass, plastic or ceramics. In some embodiments, the light emanating from the optical tip can be controlled manually or automatically. In some embodiments, the handpiece contains a self-contained power source, such as batteries. In some embodiments, the handpiece is at least in part, activated by remote control in order to prevent moving the handpiece during activation. Some embodiments include a unit operable to sense a response of nerve stimulation and to suppress a laser-ablation surgery operation.

Abstract: A catheter introduces electrodes in a vein for a minimally invasive treatment of venous insufficiency by the application of energy to cause selective heating of the vein. The catheter is positioned within the vein to be treated, and the electrodes on the catheter are moved toward one side of the vein. RF energy is applied in a directional manner from the electrodes at the working end of the catheter to cause localized heating and corresponding shrinkage of the adjacent venous tissue, which may include commissures, leaflets and ostia. Fluoroscopy or ultrasound may be used to detect shrinkage of the vein. After treating one section of the vein, the catheter can be repositioned to place the electrodes to treat different sections of the vein until all desired venous valves are repaired and rendered functionally competent.

Abstract: A system for opto-pyrometric tissue temperature monitoring in real time. The system is adapted for cardiac ablation and tissue temperature measurement, having a catheter having a tip electrode adapted for RF ablation of cardiac tissue and an optical collector whose distal end is received in an opening formed in the tip electrode to detect black body radiation from the cardiac tissue. The system includes an optical detection system in communication with the optical collector, the optical processing system processing signals representative of a wavelength of at least a portion of the black body radiation to determine a tissue temperature. The incorporation of an optical collector within a catheter tip permits real time monitoring of tissue temperature during ablation and lesion formation to prevent critical thresholds in temperature associated with events that can damage tissue, including steam pop, thrombus, char, etc.

Abstract: An illuminated laser probe primarily designed for ophthalmic surgery provides both illumination light to a surgical site and laser light to the surgical site. The probe has an elongate handle with a tubular tip extending from a distal end of the handle. A length of illumination optic fiber and a length of laser optic fiber extend through the handle and the tip. A mechanism is provided on the handle at a position where the mechanism can easily be manipulated by a finger of a surgeons hand holding the handle. The mechanism is operatively connected with the laser optic fiber and is manipulated to selectively extend a distal portion of the optic fiber from the instrument tip and retract the distal portion of the optic fiber back into the instrument tip.

Abstract: A handpiece can treat biological tissue using electromagnetic radiation, which can be substantially fluorescent light. The handpiece includes a source of electromagnetic radiation and a nonlinear waveguide. The nonlinear waveguide is adjacent the source, receives electromagnetic radiation from the source, and delivers the electromagnetic radiation to the biological tissue. The handpiece also includes a system for circulating a fluorescent substance through the nonlinear waveguide. The fluorescent substance is capable of modulating at least one property of the electromagnetic radiation.

Abstract: A laser surgical apparatus for performing treatment by irradiating a part to be treated by a laser beam is disclosed. This apparatus includes a laser source which emits the treatment laser beam; a multi-articulated arm for delivering the treatment laser beam emitted from the laser source, the arm including a plurality of light delivery pipes, a joint part for jointing the light delivery pipes, the joint part being rotatable with respect to at least one of the pipes jointed by the joint part, a reflection mirror disposed in the joint part; and a surgical instrument is connected to an end of the arm and used for irradiating the treatment laser beam delivered therein through the arm to the treatment part.

Abstract: This invention is a scanning laser device with a universal carriage that holds any type of optical element. The carriage rotates about an axis that is substantially co-axial to the incident laser beam, thereby causing the laser energy passing through the optical element to sweep through a 360° circle. The preferred embodiment uses a rod lens as the optical element, resulting in a large circular beam spot. The device may utilize laser sources of various wavelengths and pulse frequencies, and multiple devices may be combined to scan an even larger area.

Abstract: An apparatus for cutting a tissue part out of a tissue by means of focused laser radiation, comprising a suction ring which has a sealing surface that is capable of being applied onto a surface of the tissue, devices for generating an underpressure in a cavity that is delimited by the sealing surface, by the surface of the tissue and by the suction ring, and an applanation plate that is capable of being pressed against the surface of the tissue for the purpose of shaping, and a body that is opaque to the laser radiation, that interacts with the suction ring and with its inner edge defines an edge of the tissue part.

Abstract: A method and apparatus for fat destruction and body contouring. The method comprises pre-heating treated tissue and applying a high voltage pulse to destroy adipose tissue. The device includes an energy source for tissue heating and an HV pulse generator for applying voltage pulsed in the range of 200V to 5 kV.

Abstract: Described are a handpiece, a coupling, and a device with a laser source and handpiece for emitting a laser beam for dental treatment. In order to avoid damage to the healthy tooth tissue, an improved determination of the tooth temperature by measurement of at least part of the heat radiation emitted from the treatment area using a temperature sensor, preferably an infra-red sensor, is carried out. Upon reaching or exceeding a temperature threshold, the emission of the laser beam to the treatment area is interrupted or the power output of the laser source reduced or the user made aware of the violation of the threshold value using an acoustic or visual signal. The temperature sensor can be located, e.g., on the handpiece or on the coupling, such as on the coupling tube.

Abstract: The invention relates to methods of processing biological tissue using an ultrashort pulse (USP) laser. In one embodiment, the invention relates to a method of separating transverse layers or portions of a biological tissue using USP laser. In an alternative embodiment, the invention relates to a method of cutting biological tissue using USP laser. In another embodiment, the invention relates to a method of removing unwanted material from the surface of a biological tissue comprising application of the USP laser to the tissue surface.

Abstract: A surgical instrument is provided, including: at least one articulatable arm having a distal end, a proximal end, and at least one joint region disposed between the distal and proximal ends; an optical fiber bend sensor provided in the at least one joint region of the at least one articulatable arm; a detection system coupled to the optical fiber bend sensor, said detection system comprising a light source and a light detector for detecting light reflected by or transmitted through the optical fiber bend sensor to determine a position of at least one joint region of the at least one articulatable arm based on the detected light reflected by or transmitted through the optical fiber bend sensor; and a control system comprising a servo controller for effectuating movement of the arm.

Abstract: An improved optical fiber comprising a waveguide with an input for coupling focused laser energy into the waveguide and communicating electromagnetic radiation in a propagation direction to an internally reflective tip of the waveguide, a tissue contacting surface wherein the light path from the reflecting surface to the transmitting surface in substantially homogenous in refractive index and cooled by fluid flow. In minimizing the variations in refractive index within the lateral light path, while providing active cooling directly below the tissue contact surface, the invention prevents internal reflections and beam distortion and greatly improves the efficiency and durability of the laterally directing probe. Free rotation of the tissue contact surface, about the lateral tip, may be provided and tissue vaporization efficiency may be improved by providing a morcellating tool on the tissue contact surface.

Abstract: A treatment apparatus includes a cannula with a cannula lumen. The cannula has a first average diameter. A probe is positionable in the cannula lumen. The probe has a first section with a second average diameter and a second section with a third average diameter that is less than the second average diameter. At least a portion of the second section has a curved section with at least one radius of curvature. The radius of curvative is selected to provide that as the second section passes through the cannula lumen a first side of the second section is tangential to a first side of the cannula lumen, and a second opposing side of the second section is tangential to a second opposing side of the cannula lumen.

Abstract: Exemplary embodiments of the present disclosure provide methods and apparatus for heating and removing subcutaneous fatty tissue using radiation. For example, an ablative laser or the like can be configured to generate a small hole in skin tissue that passes through the entire layer of dermal tissue. The hole size can be small, e.g., on less than about 1 mm or 0.5 mm in diameter. Continued application of the radiation can heat and/or vaporize subcutaneous fat proximal to the lower portion of the hole. Expansion of the heated or vaporized fatty tissue can facilitate ejection of the fatty tissue from the formed hole. The energy of a radiation pulse used to form a hole and heat the fatty tissue can be, e.g., greater than about 0.5 J, e.g., between about 0.5 J and about 35 J. The skin tissue can be cooled or partially frozen before forming one or more such holes therein, and a stabilizing film or plate may be adhered to the skin surface to help stabilize the ablated holes.

Abstract: A cannula for a liposuction device includes an energy source for liquefying, emulsifying or softening fatty tissue near a tip end. The energy source can provide laser energy through a fiber optic cable, or can provide energy such as RF, ultrasound or IR/UV/Vis energy from a laser diode or the like. Fat is emulsified, liquefied or softened by the energy emitted from the cannula and is removed by aspiration through a series of holes disposed in the outside wall and at the distal end of the cannula. In a power assisted embodiment, the openings in the cannula shear or cut neighboring fat tissue. The tip of the cannula can be heated to promote skin tightening.

Abstract: An apparatus for performing minimally invasive surgery, for example, percutaneous minimally invasive capsulotomy surgery. The apparatus includes a shaft, a blunt tip, a flange, an energy conductor and an active surgical element, which may be a cutting or heating element. The shaft has a first end and a second end and is generally stiff with a degree of flexure; the shaft may be curved along at least a substantial part of its length to facilitate navigating the blunt tip within a patient's body. The blunt tip is at the second end of the shaft and may be larger in diameter than the shaft and with a recessed area along a surface of the blunt tip. The flange is located at the second end of the shaft and is configured to receive a device that delivers energy, which may be in the form of heat, laser light, radio-frequency, or electricity. The energy conductor is disposed along the length of the shaft from the second end of the shaft to the recess, the energy conductor configured to conduct the energy.

Abstract: In some embodiments, without limitation, the invention comprises a catheter having an elongated housing with a channel disposed therein. A laser delivery member is movable and at least partially disposed within the channel. A ramp is disposed within the housing at an angle to its central axis and proximate to its distal end. The ramp is adapted to move the distal end of the laser delivery member outwardly from the central axis of the housing. A guidewire biases the distal end of the laser delivery member generally inwardly toward the central axis of the housing. In some embodiments, without limitation, the offset of the central axis of the tip of the laser delivery member from the central axis of the housing is determined by adjusting the extent to which the laser delivery member travels on the ramp, and disposition of the laser delivery member on the guidewire maintains the offset tip substantially parallel to the central axis of the housing.

Abstract: A laser device (10) for ablating a biological tissue (1), comprising: a) a laser source (7) that is configured to emit a laser beam (4); b) optics (8a, 8b, 8x) configured to modify the laser beam (4) such as to direct the laser beam (4) on the biological tissue (1); d) a controller (11) that is configured to control the laser source (7) to emit the laser beam (4) to create an ablation in biological tissue (1), whereby e) a sensor (19) being configured to receive back scattered light from the biological tissue (1); f) a tissue controller (18) that is operationally coupled to the sensor (19) to receive a sensor signal (Ri) of the sensor (19); and g) the tissue controller (18) being configured to compare a series of at least two consecutive sensor signals (R1,R2, R3, . . . ) and being configured to generate a tissue control signal (TCS) when the value of the series of consecutive sensor signals (R1, R2, R3, . . . ) decreases in a predetermined amount.

Abstract: An apparatus having an excitation source that includes at least one laser diode and also having a handpiece with a disposable, bendable tip cannula is disclosed.

Abstract: The present invention relates to an apparatus (1) for applying energy to an object (2), wherein the apparatus (1) comprises an energy emitting element, a temperature sensor and a tube (6), in which the energy emitting element and the temperature sensor are locatable. The energy emitting elements is adapting for applying energy to the object (2) and the temperature sensor is adapted for sensing the temperature of the object (2). Both, the energy emitting element and the temperature sensor can be guided to a location of the object (2), at which the energy is to be applied.

Abstract: The present invention relates to a medical device of an endoscopic type providing a visually observable image of an examination area in an interior of an organism, which is typically used in the medical field for diagnostic purposes. The present invention is intended for the minimally invasive in-situ examination and analysis of organs and tissues preferably in the interior of a living human being or animal.

Abstract: A surgical apparatus for ablation, incision, and/or coagulation of biological tissue, the surgical apparatus comprising: at least one high intensity light emitting diode (LED) light source for producing a light beam with high power density; and an optical system for delivering said light beam to be absorbed by the biological tissue. The power density of the light beam is above a predetermined threshold level to increase a temperature of the biological tissue and cause a transformation for at least one constituent of the biological tissue for ablation, incision, and/or coagulation of the biological tissue.

Abstract: The present invention relates to gold nanocages containing magnetic nanoparticles and a preparation method thereof. More specifically, relates to hollow-type gold nanocage particles, which contain iron oxide nanoparticles having a magnetic property and have an optical property of strongly absorbing or scattering light in the near-infrared (NIR) region, as well as a preparation method thereof. Due to their optical property and magnetic property, the magnetic nanoparticle-containing gold nanocages can be used in various applications, including analysis in a turbid medium with light, cancer therapy or biomolecular manipulation using light, contrast agents for magnetic resonance imaging, magnetic hyperthermia treatment and drug delivery guide, etc.

Abstract: An imaging method includes providing a handpiece having a probe tip insertable into human or animal tissue disposed at an end thereof, and, an optical coherence tomography (OCT) probe connected to the handpiece such that a functionality of the OCT probe is provided at the probe tip. The probe tip is disposed adjacent to or into human or animal tissue. Imaging of the tissue, measuring at least one of a feature size or a quantifiable characteristic of a structure in the tissue for biometry analysis, and/or performing a diagnostic procedure on the tissue or a device implanted in the tissue is performed with the OCT probe.

Abstract: A device includes a handpiece having a probe tip disposed at an end thereof, and, connected to the handpiece such that, at the probe tip, a functionality of each is provided, a plurality of probes. The probes may include an optical coherence tomography (OCT) probe, an endoillumination probe, a laser therapy probe, an ultrasound imaging probe, an electrocautery probe, an RF ablation probe, a cryosurgical probe, an irrigator, and/or a mechanical probe.

Abstract: A medical or cosmetic hand-held laser device with an optical waveguide device is subdivided into a first section and a second section arranged at an angle thereto for emitting laser radiation onto a treatment area. To deflect the laser beam from the first section into the second section as effectively as possible and in particular to launch the laser beam with the lowest possible loss into a waveguide that conducts the laser beam further, the hand-held device is provided with a reflector that is arranged between the two sections and has an essentially elliptical reflective surface.

Abstract: The invention relates to a handpiece for radiating light onto a skin surface during a medical or cosmetic skin treatment. An optical coupling element (6) is provided in said handpiece (1). The light entrance surface (8) of said coupling element faces towards a light source, while its light exit surface (5) is in contact with the skin surface (2) during the skin treatment. The invention provides that the coupling element (6) of a handpiece (1) of this type consists of a bundle of light guides which end in the light entrance surface (8) and in the light exit surface (5) and which are in such close lateral contact with each other, at least in their end sections, that there are no optically ineffective intermediate spaces.

Abstract: Photodynamic therapy (PDT) is used in the case of bone. A photosensitizing drug is administered to a mammal. A bone insertion member is secured into bone. A fiber optic cable sheath extends from within the bone insertion member and is accessible. A fiber optic cable is inserted in the fiber optic cable sheath to deliver light to the bone. A locking member is then attached to the insertion member. Non-thermal light at a specific wavelength is then delivered to activate the drug. The insertion member and the fiber optic cable sheath may remain inside the mammal for further photodynamic therapy.

Abstract: The present disclosure relates to a portable irradiating arrangement having a light source, particularly a laser diode, comprising an outer sleeve, an inner sleeve, and a radiation distributing probe, whereby the inner sleeve is mounted in the outer sleeve and the radiation distributing probe may be attached at a probe-facing end of the outer sleeve, whereby the irradiating arrangement is designed in such a way that the light source can be turned on only when the radiation distributing probe is attached to the outer sleeve. The invention relates further to a portable irradiating arrangement, in which the inner sleeve is in contact with the radiation distributing probe in such a way that the inner sleeve must be detached from the radiation distributing probe before removal of the radiation distributing probe from the outer sleeve.

Abstract: A laser probe including a handpiece and a rigid cannula fixed to the handpiece to prevent relative translational movement-therebetween. An optical fiber for delivering laser energy is supported for translational movement relative to the handpiece. A slidable button is fixed to the optical fiber via a rigid sleeve such that the button and optical fiber move together in the same direction during operation. The fiber may be selectively positioned relative to the button to cause the button to act as a visual indicator of the direction in which the fiber will extend from the cannula. The button may be specially configured with an enlarged head portion to enhance grippability and smooth operation of the button.

Abstract: The invention provides minimally invasive microsurgical tools and methods to form an aqueous humor shunt or bypass for the treatment of glaucoma. The invention enables surgical creation of a tissue tract (7) within the tissues of the eye to directly connect a source of aqueous humor such as the anterior chamber (1), to an ocular vein (4). The tissue tract (7) from the vein (4) may be connected to any source of aqueous humor, including the anterior chamber (1) ), an aqueous collector channel, Schlemm's canal (2), or a drainage bleb. Since the aqueous humor passes directly into the venous system, the normal drainage process for aqueous humor is restored. Furthermore, the invention discloses devices and materials that can be implanted in the tissue tract to maintain the tissue space and fluid flow.