Abstract: An ophthalmic multifocal switchable lens includes a deformable element manifesting elevated strain with a formable surface of a multifocal surface shape to provide far and near vision. A transparent chamber is filled with optical matching fluid adjacent to the side of the deformable element opposite to the formable surface. The optical matching fluid has a refractive index that matches a refractive index of the deformable element material. A holding chamber is also filled with the optical matching fluid and connected with the transparent chamber with a means for preventing the optical fluid from being transported from the holding chamber to the transparent chamber which would reduce a strain of the deformable element. A split of light between far and near vision of the multifocal switchable lent changes upon a removal of the means to allow a flow of the optical matching fluid into the transparent chamber.

Abstract: A switchable intraocular lens assembly includes an optic body having a guiding surface, a holding chamber, a blocking channel, and a laser accessible cavity at a portion of the blocking channel. An elastic film is disposed over the guiding surface, wherein the elastic film is sealed at or near the guiding surface periphery forming a transparent chamber between the guiding surface and the elastic film. A laser flowable blocking element has an enlarged head connected to an extension portion, where a length of the extension portion is more than a distance along the blocking channel from the blocking channel opening to the fluidic connection of the transparent chamber. The extension portion of the laser flowable blocking element is disposed inside the blocking channel. An optical fluid is disposed within the holding chamber under a pressure greater or lesser in comparison to a pressure in the transparent chamber.

Abstract: Intraocular devices for use in and attached to the natural lens capsule of an eye are provided. The lens capsule may be maintained in a configuration to avoid post-operative changes that are deleterious to vision. Single or dual optic systems are provided, which may be accommodating. Combinations of devices to obtain dual optic systems are disclosed.

Abstract: The lens geometry and power of an intraocular lens is optimized to provide both distance and near vision correction for a patient. The optimization may be based on one or more measured accommodation-related parameters and one or more estimated accommodation-related parameters. An accommodative amplitude may be predicted based on the measured and estimated accommodation-related parameters, and the optimized the intraocular lens geometry and power established based thereon.

Abstract: A variable-optic powered or electronic ophthalmic lens may be utilized to augment the eye's natural ability to refract light or focus. The variable-optic powered lens comprises an electronic system that includes a power source, power management circuitry, clock generation circuitry, control algorithms and circuitry and lens driver circuitry. The ophthalmic lens may also comprise one or more sensors configured to detect ciliary muscle signals and adjust the optics of the lens accordingly.

Abstract: An electro-active ophthalmic lens includes an electromyography sensor, a processor, and an electro-active optical element. The electromyography sensor is configured to detect an electric field in a ciliary muscle of the eye that is proportional to a force exerted by the ciliary muscle and to generate a sensor signal indicative of the electric field. The processor is operable to receive the signal from the electromyography sensor and to determine, based on the sensor signal, an adjustment to optical power for an electro-active optical element and to generate a control signal for the electro-active optical element. The electro-active optical element is operable to receive the control signal and to change an optical power of the electro-active optical element in response to the control signal.

Abstract: An accommodating intraocular lens for providing a range of accommodative vision includes a deformable optic. The deformable optic includes a plurality of layers that have a progressively increasing hardness and/or refractive index characteristic from the outermost layer to the innermost layer to provide a range of accommodative power.

Abstract: An accommodating intraocular lens (IOL) comprises a lens, a flexible surface, and an articulating member joining the lens and the flexible surface. The articulating member comprises first and second arms extending from and joined to form a peripheral portion. The peripheral portion has a length extending radially away from a point at which the first and second arms join together and a thickness that is greater than each of a thickness of the first arm and a thickness of the second arm, first and second arms coupling the lens and the flexible surface, respectively. A flex region is disposed about the second arm and at a distance from the peripheral portion. The flex region permits the flexible surface to articulate relative to the second arm. The flex region has a reduced thickness as compared to each of the second arm and the flexible surface.

Abstract: An accommodating intraocular lens (AIOL) adapted for implantation into a capsular bag includes an outer shell, a valve, and a force transfer assembly. The outer shell includes at least one surface modification on at least a periphery of the outer shell to promote bonding with the capsular bag. The valve is configured to permit injection of a fill material. The force transfer assembly in the outer shell is adapted to transfer forces from the capsular bag to change the shape of the filled outer shell in response to changes in capsular bag shape.

Abstract: An accommodative intraocular lens (IOL) system is disclosed for insertion into an eye to provide accommodative vision, the system including a deformable air chamber filled with a transparent, low refractive index medium disposed between the first and second optics; and at least one haptic connected to the air chamber and configured to facilitate a change in the curvature of at least one surface of the chamber, such that when the lens system is positioned in an eye, cilliary muscle movements can alter the curvature of the air chamber and vary the overall lens power of the system.

Abstract: A curvature changing accommodative intraocular lens for implantation into the eye of a patient includes a lens body having a base lens which has a base lens power, and a haptic structure including haptic elements projecting from the base lens. An actuator is placed into engagement with the lens body, and includes actuator haptic elements. At least one fluidic optical element is received between the actuator and base lens of the lens body and contains a fluid material therein. During accommodation of the patient's eye, the haptic elements of the lens body and actuator are engaged and apply a force to the fluidic optical element, causing the fluidic optical element to be deformed to generate an additional lens power to adjust the patient's vision.

Abstract: The present invention relates generally to an intraocular lens system controlled with a processor, including a liquid meniscus lens and supporting electronics. Embodiments may include intraocular lens systems of various shapes and sizes, liquid meniscus lens components of various shapes and sizes, variations in supporting electronics with corresponding variations in lens function.

Abstract: An accommodating intraocular lens (AIOL) assembly (10) including an optics assembly (12) including an inflatable member (14), and characterized by an extra-capsular-bag interface structure (16) for interfacing with ocular structure of an eye external to a capsular bag for implanting the AIOL (10) outside the capsular bag, the extra-capsular-bag interface structure (16) including a less-rigid portion (18) and a more-rigid portion (20) that define a volume therebetween which is at least partially filled with a fluid (22) and which is in fluid communication with the inflatable member (14) via at least one conduit (24), and wherein the less-rigid portion (18) is responsive to movement of the ocular structure to apply a pumping force on the fluid (22) to cause the fluid (22) to flow via the at least one conduit (24) to the inflatable member (14) so as to change the optical power of the optics assembly (12).

Abstract: The invention relates to a intraocular lens system having a flexible anterior lens accommodation material behind the lens. The accommodation material may comprise of one or more macromers, which, when polymerized, adjust the properties of the accommodation material. The anterior lens is flexible such that the curvature of the lens changes during accommodation. The anterior lens may be used alone or in combination with a posterior lens.

Abstract: An intraocular lens (IOL) that provides for optical power adjustment following its implantation, for example, for use in treating cataract patients. The lens body has first and second surface portions that bound at least one interior chamber or space that extends from the central optic portion to the lens periphery. The interior chamber or space has a microporous body that is intermediate inner and outer portions of the space. In one embodiment, the microporous body is capable of cooperating with an external Rf or light source to expose a charge to a charge-carrying fluid within the interior chamber. By this system, fluid flows are induced to alter the optical parameters of the lens.

Abstract: A vision prosthesis includes an intra-ocular lens system having a variable focal length; and a controller that causes a change in the focal length thereof.

Abstract: Fluids incorporated into intraocular lenses and their methods of use. In some embodiments the fluids are silicone oils, and in some embodiments they are used in accommodating intraocular lenses.

Abstract: An accommodating (re-focusable) intraocular lens (IOL), a body of which includes two optical portions sequentially disposed, in optical contact with one another, along an optical axis and separated by interior surface the curvature of which is changing in response to pressure applied to posterior surface of IOL. The two optical portions may be formed with fluids having different refractive indices and housed in flexible cells that share an interior wall having such interior surface. The wall bends or flexes in response to force, caused by flexing of ciliary body muscle when IOL is installed in eye's capsule's membrane and passed onto the body of IOL via bendable haptics integrated with the optical portion(s) along a perimeter. The optical power of the IOL is gradually modifiable in part due to change of curvature of the interior surface.

Abstract: An object is to provide an artificial lens for use in an artificial eye device for cataract surgery practice. The artificial lens includes an artificial nucleus corresponding to a human eye lens nucleus and an artificial cortex corresponding to a human eye lens cortex. The artificial nucleus is formed of an agar gel of agar concentration 1.0 wt % to 5.0 wt %. The artificial cortex is formed of an agar gel of agar concentration 0.5 wt % to 1.5 wt % which is lower than the agar concentration of an agar gel forming the artificial nucleus. In another embodiment, an artificial lens includes an artificial nucleus corresponding to a human eye lens nucleus and an artificial cortex corresponding to a human eye lens cortex. The artificial nucleus is formed of cheese or a cheese-like substance, and the artificial cortex is formed of pulp fiber.

Abstract: An accommodating intraocular lens comprises a first lens component, a second lens component, and an adhesive between portions of the two lens components. The cured adhesive bonds the lens components to form a fluid chamber. The lens components are bonded to one another along a seam which extends circumferentially along at least a portion of the lens components. The lens components may comprise the same polymer material. The cured adhesive also comprises the polymer or a prepolymer of the polymer to provide increased strength. The polymer is hydratable such that the lens components and the cured adhesive therebetween can swell together to inhibit stresses between the lens components and the cured adhesive.

Abstract: Systems, devices, and methods are presented for a prosthetic injectable intraocular lens. One or more silicone elastomeric patches located outside the optical path on the anterior side but away from the equator can be accessed by surgical needles in order to fill or adjust optically clear fluid within the lens. The fluid can be adjusted in order to set a base dioptric power of the lens and otherwise adjust a lens after its initial insertion. The elastomeric patches are sized so that they self-seal after a needle is withdrawn. A straight or stepped slit in the patch can allow a blunt needle to more easily access the interior of the lens.

Abstract: A curvature changing accommodative intraocular lens is provided in which the anterior surface of the intraocular lens undergoes dynamic change in curvature to focus light from distant objects to those nearby. The lens utilizes fluid movement from bladders defined as junctions between haptic elements and lens element or bladders positioned between the haptic elements and lens element periphery to change the curvature.

Abstract: A dynamic accommodative intraocular lens is provided in which a central lens portion of the intraocular lens undergoes dynamic change in curvature to adjust focus from distant objects to those nearby in response to natural accommodative actions of the patient's eye. The intraocular lens utilizes fluid movement from flexible fluid reservoirs defined along or adjacent haptic elements of the intraocular lens, which are engaged and compressed by the accommodating movements of the ciliary body of the patient's eye to cause expansion and flattening of the intraocular lens to adjust the optic power of the lens.

Abstract: A curvature changing accommodative intraocular lens for implantation into the eye of a patient includes a lens body having a base lens which has a base lens power, and a haptic structure including haptic elements projecting from the base lens. An actuator is placed into engagement with the lens body, and includes actuator haptic elements. At least one fluidic optical element is received between the actuator and base lens of the lens body and contains a fluid material therein. During accommodation of the patient's eye, the haptic elements of the lens body and actuator are engaged and apply a force to the fluidic optical element, causing the fluidic optical element to be deformed to generate an additional lens power to adjust the patient's vision.

Abstract: An insertion device is disclosed which is suitable for use of liquid as lubricant such as normal saline. The insertion device for inserting a lens into an eye comprises a main body having a nozzle at its front end, and a pushing member for pushing the lens set in the main body into an eye through the nozzle. The pushing member includes an introducing portion through which liquid is introduced and a flow path for supplying the liquid introduced from the introducing portion into the main body.

Abstract: This invention relates to intraocular lenses. More particularly, this invention relates to intraocular lenses that have the ability to alter the light refractive power in response to changes in the tension of the ciliary muscle or ciliary body of the eye or any other accommodative forces. Lenses of this invention are generally referred to as interfacial, i.e., lens properties being defined as the interface of two liquids having different refractive indices, refractive accommodating lenses (IRAL).

Abstract: A multi-focus intraocular prosthesis is provided that makes use of fluid substitution to change the power of the prosthesis. Also provided are methods of making and using the same.

Abstract: An intraocular lens is adapted for insertion into a capsular bag having a zonular contact region. The intraocular lens comprises a shape changing optical element and an accommodating element comprising at least one force transmitting element and a plurality of spaced apart contacting elements each adapted to contact a portion of the zonular contact region and transmit compressive displacement radially inward at an oblique angle to the optical element and configured to cooperate with at least one of the ciliary muscle of the mammalian eye, the zonules of the mammalian eye and the vitreous pressure in the eye to effect an accommodating shape and a disaccommodating shape change to the optical element.

Abstract: Systems, devices, and methods are presented for a prosthetic injectable intraocular lens. The lenses can be made from silicone, fluorosilicone, and phenyl substituted silicone and be semipermeable to air. One or more silicone elastomeric patches located outside the optical path on the anterior side but away from the equator can be accessed by surgical needles in order to fill or adjust optically clear fluid within the lens. The fluid can be adjusted in order to set a base dioptric power of the lens and otherwise adjust a lens after its initial insertion. The elastomeric patches are sized so that they self-seal after a needle is withdrawn. A straight or stepped slit in the patch can allow a blunt needle to more easily access the interior of the lens.

Abstract: An implantable ophthalmic device connectable to an implantable accommodating lens includes a dual-chamber sensor cell having a first and second plate where the second plate is disposed opposite the first plate. A first chamber with a first flexible membrane is disposed on an inner side of the first plate. A second chamber with a second flexible membrane is disposed on an inner side of the second plate. A space resides between the first and second chambers configured to receive a scleral spur of a ciliary muscle of a patient's eye. A connecting element is attached at a first end to the dual-chamber sensor cell. The connecting element includes a first and second channel disposed along a length of the connecting element and in communication with the first and second chamber of the dual-chamber sensor cell, respectively. The second end of the connecting element is connectable to the implantable accommodating lens.

Abstract: An ophthalmic multifocal switchable lens includes a deformable element manifesting elevated strain with a formable surface of a multifocal surface shape to provide far and near vision. A transparent chamber is filled with optical matching fluid adjacent to the side of the deformable element opposite to the formable surface. The optical matching fluid has a refractive index that matches a refractive index of the deformable element material. A holding chamber is also filled with the optical matching fluid and connected with the transparent chamber with a means for preventing the optical fluid from being transported from the holding chamber to the transparent chamber which would reduce a strain of the deformable element. A split of light between far and near vision of the multifocal switchable lent changes upon a removal of the means to allow a flow of the optical matching fluid into the transparent chamber.

Abstract: The invention provides for an inflatable intra ocular lens/lens retainer or a system of inflatable intra ocular lens/lens retainers, which are fitted into an aphakic eye, to substantially occupy the space previously held by the crystalline lens to retain and secure the position of delicate intra ocular structures of the eye. The inflatable lens/lens retainer may also be used suspend optical interfaces along the visual axis of the eye. The inflatable intra ocular lens/lens retainer may be pressed against residual elements of the lens capsule to re-establish accommodation. In the absence of a lens capsule, the inflatable intra ocular lens/lens retainer may be compressed directly by the ciliary muscle to alter the refractive state of the eye.

Abstract: This invention relates to intraocular lenses. More particularly, this invention relates to intraocular lenses that have the ability to alter the light refractive power in response to changes in the tension of the ciliary muscle or ciliary body of the eye or any other accommodative forces. Lenses of this invention are generally referred to as interfacial, i.e., lens properties being defined as the interface of two liquids having different refractive indices, refractive accommodating lenses (IRAL).

Abstract: A prosthesis is provided, which includes anterior and posterior lenses spaced from one another and aligned along an optical axis, and an optic body supporting the lenses in spaced relation to one another to establish a chamber between the lenses. Optically transmissive primary and secondary fluids are contained in the chamber. Orienting the optical axis in a horizontal orientation for far vision positions the optical axis through the primary fluid. Orienting the optical axis for near vision at a range of effective downward angles relative to the horizontal orientation positions the optical axis to extend through the primary fluid and the secondary fluid. The prosthesis may further include an internal plate between the lenses, which may be offset at an oblique angle relative to perpendicular to the optical axis. Related methods are also provided.

Abstract: A lens in accordance with the present invention includes an accommodating cell having two chambers with at least one chamber filled with optical fluid with the refractive index matching the refractive index of the accommodating element separating them. The accommodating element has a diffractive surface with surface relief structure that maintains its period but changes its height due a pressure difference between the chambers to redirect most of light that passes through the lens between different foci of far and near vision. The invention also includes a sensor cell that directly interacts with the ciliary muscle contraction and relaxation to create changes in pressure between the accommodating cell chambers that results in changing surface relief structure height and the lens accommodation.

Abstract: A fluidic telescope includes a first lens configured to be arranged in the eye of a patient, and a second lens having a chamber with fluid disposed therein, the second lens being a variable focus fluidic lens capable of varying the shape thereof so as to selectively form an additive plus lens, an additive minus lens, and a Galilean telescope when positioned so as to be along the same optical axis as the first lens, wherein the second lens is configured to be capable of moving the focal point thereof forward or backward by increasing or decreasing the fluid in the chamber.

Abstract: An implantable intraocular lens and methods of manufacturing them provide a target degree of optical accommodation. In various embodiments, the lens includes at least one internal optic, an outer shell for enclosing at least a portion of the internal optic, and a fluid at least partially filling the outer shell.

Abstract: A telescopic intraocular lens system comprises a telescopic optical system comprising an anterior optic interconnected with a posterior optic. The optics are substantially aligned on an optical axis of the optical system. The optics are formed from a soft material and the optics are substantially immovable relative to each other along the optical axis in response to accommodative forces of the type observed in the capsular bag of the human eye.

Abstract: The invention provides for an inflatable intra ocular lens/lens retainer or a system of inflatable intra ocular lens/lens retainers, which are fitted into an aphakic eye, to substantially occupy the space previously held by the crystalline lens to retain and secure the position of delicate intra ocular structures of the eye. The inflatable lens/lens retainer may also be used suspend optical interfaces along the visual axis of the eye. The inflatable intra ocular lens/lens retainer may be pressed against residual elements of the lens capsule to re-establish accommodation. In the absence of a lens capsule, the inflatable intra ocular lens/lens retainer may be compressed directly by the ciliary muscle to alter the refractive state of the eye.

Abstract: An accommodating intraocular lens is provided in which a deflectable lens element is anchored to a substrate along its optical axis to define a fluid filled space. Fluid-filled haptics disposed in fluid communication with the space vary the fluid volume in the space responsive to forces applied by the ciliary muscles, thereby causing the periphery of the lens element to deflect relative to the substrate and changing the optical power of the intraocular lens.

Abstract: A lens driver or lens driver circuitry for an ophthalmic apparatus comprising an electronic system which actuates a variable-focus optic is disclosed herein. The lens driver is part of an electronic system incorporated into the ophthalmic apparatus. The electronic system includes one or more batteries or other power sources, power management circuitry, one or more sensors, clock generation circuitry, control algorithms and circuitry, and lens driver circuitry. The lens driver circuitry includes one or more power sources, one or more high voltage generators and one or more switching circuits.

Abstract: According to a first aspect, the invention relates to an electrically controlled focusing ophthalmic device (43) to be worn by a user, comprising:—at least one active liquid lens comprising a liquid/liquid interface movable by electrowetting under the application of a voltage,—a driver for applying a DC voltage to said active liquid lens, the amplitude of the voltage to be applied being a function of the desired focusing;—a sensor (41) for detecting eyelid closing events and/or microsaccades of the user;—a controller for synchronizing said sensor and the driver, such that the driver may reverse the polarization of the DC voltage during a microsaccade and/or an eyelid closing event of the user.

Abstract: An implantable ophthalmic device with flexible, fluid-filled membranes provide dynamically variable optical power to restore lost accommodation in individuals suffering from presbyopia or aphakia without moving parts or reducing the amount of transmitted light. Actuating the device causes the fluid-filled membrane to change curvature, which produces a corresponding change in optical power. For instance, squeezing the edge of the membrane causes the center of the membrane to bulge by an amount proportional to the squeezing force. Alternatively, heating or applying a voltage to the membrane may cause the liquid in the membrane to undergo a phase transition accompanied by a corresponding change in volume that causes the membrane to inflate so as to change the optical power of the device.

Abstract: The present invention relates generally to an intraocular lens system controlled with a processor, including a liquid meniscus lens and supporting electronics. Embodiments may include intraocular lens systems of various shapes and sizes, liquid meniscus lens components of various shapes and sizes, variations in supporting electronics with corresponding variations in lens function.

Abstract: An accommodating intraocular lens, for use in an eye, is made from flexible, bio-compatible lens body material surrounding a closed and sealed lens cavity which is filled with bio-compatible optical liquid. The optical liquid has a refractive index sufficiently high to, in cooperation with the ciliary muscle and accommodation of the lens body. focus light, incident on the eye, on the retina, and thus to provide accommodation. Connecting structure of the lens is interfaced with the ciliary muscle of the eve. The pressure expressed by the ciliary muscle, during the accommodative effort, is received by the connecting structure as a pushing force, and is transferred, as a pushing force, to the lens body, thus to change the radius of curvature of the anterior body member and/or the posterior body member, thus providing smooth focusing, including from far distance in the relaxed state to near distance in the accommodative state.

Abstract: A fundus camera includes three fluidic lenses, each fluidic lens having a chamber configured so as to capable of having a fluid inserted therein or removed therefrom, such that the shape of each of the three fluidic lenses is capable of being changed based on an amount of fluid therein, a refractive or diffractic telescopic system, a Shack-Hartmann sensor configured to automatically control of the amount of the fluid in the chamber of each of the three fluidic lenses, so as to be capable of correcting refractive errors in an eye, and a multifunction camera configured for precision of fundus photography.

Abstract: A fluidic telescope includes a first lens configured to be arranged in the eye of a patient, and a second lens having a chamber with fluid disposed therein, the second lens being a variable focus fluidic lens capable of varying the shape thereof so as to selectively form an additive plus lens, an additive minus lens, and a Galilean telescope when positioned so as to be along the same optical axis as the first lens, wherein the second lens is configured to be capable of moving the focal point thereof forward or backward by increasing or decreasing the fluid in the chamber.

Abstract: Systems, devices, and methods are presented for a prosthetic injectable intraocular lens. The lenses can be made from silicone, fluorosilicone, and phenyl substituted silicone and be semipermeable to air. One or more silicone elastomeric patches located outside the optical path on the anterior side but away from the equator can be accessed by surgical needles in order to fill or adjust optically clear fluid within the lens. The fluid can be adjusted in order to set a base dioptric power of the lens and otherwise adjust a lens after its initial insertion. The elastomeric patches are sized so that they self-seal after a needle is withdrawn. A straight or stepped slit in the patch can allow a blunt needle to more easily access the interior of the lens.

Abstract: An accommodating intraocular lens is provided in which a deflectable lens element is anchored to a substrate along its optical axis to define a fluid filled space. Fluid-filled haptics disposed in fluid communication with the space vary the fluid volume in the space responsive to forces applied by the ciliary muscles, thereby causing the periphery of the lens element to deflect relative to the substrate and changing the optical power of the intraocular lens.

Abstract: Accommodating intraocular lenses and methods of use. The accommodating intraocular lenses include peripheral regions that are adapted to be more sensitive to certain types of forces than to other types of forces.