Abstract: An accommodating intraocular lens includes an adjustable optic, wherein the optic is capable of being moved between an accommodated state and an unaccommodated state. The optic includes an anterior portion, a posterior portion, and a sidewall between the anterior portion and the posterior portion. The lens further includes a ring disposed about the optic sidewall and a haptic coupled to the ring. The haptic is capable of being coupled to a patient's capsular bag. A method for implanting an accommodating intraocular lens is also provided.

Abstract: An intraocular lens in which deterioration in contrast is suppressed even when the optical axis of the intraocular lens is decentered from the optical axis of the eyeball when the intraocular lens is inserted into the eye while the advantage of a conventional aberration reduction type intraocular lens that the image is seen clearly is sustained by employing such a power distribution as respectively having at least one positive power deviation region (E1) having a power larger than that represented by the reference power distribution and at least one negative power deviation region (E2) having a power smaller than that represented by the reference power distribution in the central region of the intraocular lens assuming that a power distribution being set to cancel the spherical aberration of cornea when the intraocular lens is inserted into the eye is the reference power distribution.

Abstract: An intraocular lens for insertion into the capsular bag of an eye contains an optic, an outer periphery, and an outer support structure. The optic has a periphery and centered about an optical axis. The outer periphery is disposed about the optic and configured to engage an equatorial region of the capsular bag of an eye. The outer support structure is disposed along the periphery and spaced from the optic with voids outer support structure and the optic. The intraocular lens further comprises a first intermediate member and a weakened region disposed along the outer periphery between the outer support structure and the first intermediate member. The first intermediate member operably couples the optic and the outer support structure. The weakened region is attached to, and configured to provide relative motion between, the outer support structure and the first intermediate member in response to the ciliary muscle of the eye.

Abstract: A multi-element accommodating intraocular lens (AIOL) having a first anterior translation member and a first posterior translation member coupled together to form a first bias element. The first posterior translation member has a greater resistance to bending than the first anterior translation member. The first posterior translation member has a greater thickness than the first anterior translation member.

Abstract: A lens in accordance with the present invention includes an accommodating cell having two chambers with at least one chamber filled with optical fluid with the refractive index matching the refractive index of the accommodating element separating them. The accommodating element has a diffractive surface with surface relief structure that maintains its period but changes its height due a pressure difference between the chambers to redirect most of light that passes through the lens between different foci of far and near vision. The invention also includes a sensor cell that directly interacts with the ciliary muscle contraction and relaxation to create changes in pressure between the accommodating cell chambers that results in changing surface relief structure height and the lens accommodation.

Abstract: An accommodating artificial ocular lens (AAOL) device including a lens optic portion connected to a pleated lens haptic portion to provide accommodation of vision of the eye.

Abstract: An intra-ocular artificial lens with variable optical strength, having at least two optical elements, at least two of which are movable relative to each other in a direction extending transversely of the optical axis, wherein the optical elements have a form such that in different positions of the movable optical elements the artificial lens has a different optical strength, wherein the artificial lens has a fixed, positive optical basic strength wherein the variable optical strength caused by the relative movement of the movable elements is added to obtain the total optical strength of the artificial lens. Providing a different form results in the possibility of incorporating the greatest optical power in one of the optical elements. This optical element can then be optimized for the desired optical properties. The remaining optical element or the remaining optical elements can then be dimensioned for variation of the optical strength.

Abstract: An intraocular lens (IOL) assembly for correcting myopia, hyperopia and astigmatism using the intraocular lens assembly are provided. In particular, the intraocular lens assembly comprises a lens extending along an optical axis between an anterior optical surface and a posterior optical surface. The IOL has a circumferential edge disposed about the optical axis at a junction of anterior and posterior optical surfaces. The IOL assembly further has N haptics, where N is an integer greater than 1. Each haptic extends from an associated portion of the circumferential edge and along an associated haptic axis. In addition, each haptic is loop-like or paddle-like and extends between end portions at opposite ends thereof. The end portions are joined to the lens at the circumferential edge. The resultant vaulted structure provides an intraocular lens assembly that, when implanted in the eye, allows accommodation.

Abstract: A device includes a plurality of ringlets connected together to form a ring having a longitudinal axis. Each ringlet includes a first element and a second element. The first and second elements each extend from a first end through a central portion to a second end. The first and second ends are disposed at radially outer positions with respect to the ring than the central portion. The central portion is longitudinally displaced from the first and second ends. The first and second elements are separated and spaced apart from each other at the central portions thereof and are joined together at the first ends thereof and the second ends thereof. The ringlets are connected together such that the first ends of the elements of one ringlet are connected to the second ends of the elements of an adjacent ringlet.

Abstract: An intraocular lens having a light-transmitting optic (32, 94a, 94b, 142, 216) comprised of a synthetic light-refractive material (40, 102) operably coupled with a flexible optic positioning member (34, 62, 74, 84, 100, 210) to refract light onto the retina in order to correct refractive errors in the eye (10). The refractive material has an index of refraction of from about 1.36 to 1.5 or higher. The optic positioning member (34, 62, 74, 84, 100, 210) is constructed of a flexible synthetic resin material such as polymethylmethacrylate and permits focusing upon objects located near to and far from the viewer. The optic (32, 94a, 94b, 142, 216) of the present invention possess greater refractive capability than optics conventionally used in IOL construction, and permits retinal receipt of the image being viewed in order to correct refractive errors.

Abstract: An intraocular lens is disclosed, with an optic that changes shape in response to a deforming force exerted by the zonules of the eye. A haptic supports the optic around its equator and couples the optic to the capsular bag of the eye. Certain haptic features improve the accommodative performance of the haptic, such that compressive/tensile forces may be more efficiently transferred from the haptic to optic. Furthermore, certain aspects also provide enhanced bag-sizing capability so that the IOL better fits within the capsular bag.

Abstract: Generally, an intraocular implant and methods for treating an ocular condition. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye.

Abstract: Embodiments of the invention relate to an intraocular lens system having a plurality of haptics for use with an optic. In general, the haptics are adapted to move independently in response to forces associated with a ciliary muscle and/or zonules of an eye when implanted. The optic may be releasably secured to the system using, for example, a plurality of optic securing arms. Alternatively, the optic may be fused to the haptics, which may project radially outward from the optic. A restraining arm may be included to limit movement of the haptics during accommodation and/or disaccommodation. Clamping members may be included for securing the system to a capsular bag of the eye. Methods of implanting the intraocular lens system into the eye are also described.

Abstract: The invention provides for an inflatable intra ocular lens/lens retainer or a system of inflatable intra ocular lens/lens retainers, which are fitted into an aphakic eye, to substantially occupy the space previously held by the crystalline lens to retain and secure the position of delicate intra ocular structures of the eye. The inflatable lens/lens retainer may also be used suspend optical interfaces along the visual axis of the eye. The inflatable intra ocular lens/lens retainer may be pressed against residual elements of the lens capsule to re-establish accommodation. In the absence of a lens capsule, the inflatable intra ocular lens/lens retainer may be compressed directly by the ciliary muscle to alter the refractive state of the eye.

Abstract: A telescopic intraocular lens system comprises a telescopic optical system comprising an anterior optic interconnected with a posterior optic. The optics are substantially aligned on an optical axis of the optical system. The optics are formed from a soft material and the optics are substantially immovable relative to each other along the optical axis in response to accommodative forces of the type observed in the capsular bag of the human eye.

Abstract: An intraocular lens for providing a range of accommodative vision, an extended depth of focus, or enhanced performance through the asymmetric transfer of ocular forces to the lens. The intraocular lens contains an optic and a haptic. The shape and/or material of the haptic results in the transmission of ocular forces to particular regions in the optic. Greater forces applied to particular regions result in deformation of that region and increased power.

Abstract: An implantable, compressible, accommodating intra-ocular lens (IOL) coupled to at least one sensor which detects a signal created by the ciliary muscle. A ciliary sulcus ring can house the at least one sensor, and the sensor can include miniaturized electrodes (ciliary muscle probes) for implanting into the ciliary muscle of the subject. A potentiometer/microcomputer can modulate the ciliary muscle signal detected by the sensor(s) into an electrical signal, and a transmitter sends this electrical signal to a micromotor, which causes compression of the IOL via an annular support ring system, causing a change in the IOL shape. The IOL can be part of an IOL complex including a compressible, accommodating IOL, an external lens membrane, and an annular support ring system. The annular support ring system provides a foundation for the micromotor to compress the IOL.

Abstract: An intraocular lens having a light-transmitting optic (32, 94a, 94b, 142, 148, 216) comprised of a synthetic light-refractive material (40, 102) operably coupled with a flexible optic positioning member (34, 62, 74, 84, 100, 150, 210) to refract light onto the retina in order to correct refractive errors in the eye (10). The refractive material has an index of refraction of from about 1.36 to 1.5 or higher. The optic positioning member (34, 62, 74, 84, 100, 150, 210) is constructed of a flexible synthetic resin material such as polymethylmethacrylate and permits focusing upon objects located near to and far from the viewer. The optic (32, 94a, 94b, 142, 148, 216) of the present invention possess greater refractive capability than optics conventionally used in IOL construction, and permits retinal receipt of the image being viewed in order to correct refractive errors.

Abstract: A variable focus intraocular lens comprises an optic coupled to at least one haptic at a flexion that sets a non-zero angle between the optic and the haptic.

Abstract: In one aspect, an accommodative intraocular lens (IOL) is disclosed that includes an optic having at least a portion formed of a polarizable and/or and electro-active material. Once implanted in a subject's eye, a change in the index of refraction of the polarizable and/or electro-active portion in response to forces applied to the optic via the eye's ciliary muscle can cause a change in the optical power of the optic, thereby allowing accommodation.

Abstract: An intraocular lens is adapted for insertion into a capsular bag having a zonular contact region. The intraocular lens comprises a shape changing optical element and an accommodating element comprising at least one force transmitting element and a plurality of spaced apart contacting elements each adapted to contact a portion of the zonular contact region and transmit compressive displacement radially inward at an oblique angle to the optical element and configured to cooperate with at least one of the ciliary muscle of the mammalian eye, the zonules of the mammalian eye and the vitreous pressure in the eye to effect an accommodating shape and a disaccommodating shape change to the optical element.

Abstract: An accommodating intraocular lens (AIOL) comprising an optic, and at least one haptic plate coupled to the optic by at least one connector, the connector being less rigid than the haptic plate, the at least one haptic plate surrounding the optic, and the optic and haptic plate having a combined surface area between 80 mm2and 100 mm2. The at least one haptic plate may form a continuous 360-degree boundary around the optic. The at least one haptic plate has a width in a radial dimension of 1.0-3.

Abstract: An intraocular lens has a polymeric optic defined by a harder posterior layer and a softer anterior layer. Haptics having a fulcrum attached to the posterior layer and a resistance arm attached to the anterior layer are provided. A bias is provided to the haptic to rotate the haptics about the fulcrum and cause the resistance arm to deform the softer anterior layer about the harder posterior layer to increase the optical power of the lens. As the haptic rotates, it axially displaces the optic anteriorly to additionally increase the optical power. The optical power is adjustable in response to stresses induced by the eye. The haptics are subject to a pre-bias that urges the haptics to rotate or bend about the fulcrum. Temporary restraints are provided to the haptics to retain a stressed shape of the lens against the bias during a post-implantation healing period.

Abstract: An intraocular lens implant comprises two viewing elements (12, 13) and a spring element (14) in between. A distance between the first and the second viewing element (12, 13) along an optical axis (A-A?) of the lens implant (11) can be varied for adjusting the focal length of the lens implant (11). The lens implant (11) is designed to take a shape suitable for distant vision when the spring element (14) is in its relaxed state. A spring constant of the spring element (14) is dimensioned such that a force produced by a lens capsule (2) of the eye for holding the lens implant (11) transforms the spring element (14) from its relaxed state into a stretched state. By such design, the lens implant (11) may follow the same actuation principles as the natural lens does.

Abstract: An intraocular lens has a polymeric optic defined by a harder posterior layer and a softer anterior layer. Haptics having a fulcrum attached to the posterior layer and a resistance arm attached to the anterior layer are provided. A bias is provided to the haptic to rotate the haptics about the fulcrum and cause the resistance arm to deform the softer anterior layer about the harder posterior layer to increase the optical power of the lens. As the haptic rotates, it axially displaces the optic anteriorly to additionally increase the optical power. The optical power is adjustable in response to stresses induced by the eye. The haptics are subject to a pre-bias that urges the haptics to rotate or bend about the fulcrum. Temporary restraints are provided to the haptics to retain a stressed shape of the lens against the bias during a post-implantation healing period.

Abstract: An intraocular lens for providing accommodative vision to a subject includes a frame disposed about an optical axis, a first optical element, a second optical element, and a connecting element operably coupling the frame to the optical elements. The frame comprises an anterior frame element and a posterior frame element. The connecting element is configured to convert a first displacement between the frame elements in a direction that is substantially parallel to the optical axis into a second displacement between the optical elements that is substantially perpendicular to the optical axis. The second displacement may be translational and/or rotation. In some embodiments, the optical elements are two varifocal lenses.

Abstract: An accommodating intraocular implant apparatus is disclosed for implantation in the human eye. The apparatus includes an optic portion having a periphery and an optic axis, said optic portion lying substantially within an optic plane transverse to said optic axis; at least one flexible haptic extending from a point on or near the periphery of the optic portion; at least one flexible haptic having a fixation anchor portion distal to the periphery of the optic portion; and at least one flexible haptic having a centering anchor portion. The fixation anchor portion and the centering anchor portion are adapted to couple to a portion of the eye.

Abstract: A method is provided for implanting an accommodating intraocular lens system in a capsular bag of an eye. The method includes providing the accommodating intraocular lens having an anterior viewing element and a posterior viewing element. The anterior viewing element has a width in a range between approximately 4.5 millimeters and approximately 6.5 millimeters. The method further includes forming an opening in an anterior portion of the capsular bag. The opening has a minimum width not less than approximately 4 millimeters and has a maximum width not greater than approximately 6.0 millimeters. The method further includes placing the accommodating intraocular lens system within the capsular bag. The capsular bag overlaps at least a portion of the anterior viewing element and defines an overlap region with a width in a range between approximately 0.1 millimeters and approximately 0.75 millimeters.

Abstract: An intraocular lens (10) is configured so that it can be incorporated into the capsule of an eye and its refractive power can be modified by the application of electrical voltages.

Abstract: Accommodating intraocular lenses and methods of use. The accommodating intraocular lenses include peripheral regions that are adapted to be more sensitive to certain types of forces than to other types of forces.

Abstract: Fluid-driven accommodating intraocular lenses comprising deformable optic portions.

Abstract: Intraocular lenses for providing accommodation include an anterior optic, a posterior optic, and a lens structure. In one such lens, the lens structure comprises an anterior element coupled to the anterior optic and a posterior element coupled to the posterior optic. The anterior and posterior elements are coupled to one another at a peripheral region of the intraocular lens. The intraocular lens may also includes a projection extending anteriorly from the posterior element that limits posterior motion of the anterior optic so as to maintain a minimum separation between anterior optic and an anterior surface of the posterior optic.

Abstract: An implantable system for restoring accommodation capacity includes at least one ring configured to be implanted in a ciliary sulcus and a capacitor with a first capacitor plate and a second capacitor plate. The first capacitor plate is arranged on an implantable ring and the second capacitor plate is connected to a capsular bag.

Abstract: An intraocular lens is adapted for insertion into a capsular bag having a zonular contact region. The intraocular lens comprises a shape changing optical element and an accommodating element comprising at least one force transmitting element and a plurality of spaced apart contacting elements each adapted to contact a portion of the zonular contact region and transmit compressive displacement radially inward at an oblique angle to the optical element and configured to cooperate with at least one of the ciliary muscle of the mammalian eye, the zonules of the mammalian eye and the vitreous pressure in the eye to effect an accommodating shape and a disaccommodating shape change to the optical element.

Abstract: Accommodating intraocular lens (AIOL) capsules having a continuously variable Diopter strength between a first Diopter strength in a non-compressed state and a second Diopter strength different than its first Diopter strength in a compressed state. The AIOL capsules include an anterior capsule plate, a posterior capsule plate, and a capsule ring for bounding a hermetic cavity filled with a capsule filling. The anterior capsule plate is intended to anteriorly bulge along the human eye's visual axis on application of an axial compression force against the posterior capsule plate from a posterior direction.

Abstract: An intraocular lens assembly for implantation in the posterior chamber of an eye has anchor portions with teeth rigid enough to penetrate the scleral wall of an eye. A method for implanting the lens includes the steps of: introducing the first haptic portion with a first anchor portion that includes a plurality of teeth projecting therefrom, into the posterior chamber of the eye until said teeth are anchored in the scleral wall at a desired location; and moving a second haptic portion with a plurality of teeth projecting therefrom, until said teeth are anchored in the scleral wall on the opposite side of the lens from the first anchor portion.

Abstract: A method is provided for implanting an accommodating intraocular lens system in a capsular bag of an eye. The method includes providing the accommodating intraocular lens having an anterior viewing element and a posterior viewing element. The anterior viewing element has a width in a range between approximately 4.5 millimeters and approximately 6.5 millimeters. The method further includes forming an opening in an anterior portion of the capsular bag. The opening has a minimum width not less than approximately 4 millimeters and has a maximum width not greater than approximately 6.0 millimeters. The method further includes placing the accommodating intraocular lens system within the capsular bag. The capsular bag overlaps at least a portion of the anterior viewing element and defines an overlap region with a width in a range between approximately 0.1 millimeters and approximately 0.75 millimeters.

Abstract: In one aspect, the present invention provides a two-element ophthalmic lens in which a lateral shift of the elements relative to one another can cause a variation not only in a spherical power provided by the lens but also in spherical aberration exhibited by that lens. In some implementations, the thickness profiles of the two elements are designed such that the variation in spherical aberration is positively correlated with that of the spherical power of the lens.

Abstract: A lens in accordance with the present invention includes an accommodating cell having two chambers with at least one chamber filled with optical fluid with the refractive index matching the refractive index of the accommodating element separating them. The accommodating element has a diffractive surface with surface relief structure that maintains its period but changes its height due a pressure difference between the chambers to redirect most of light that passes through the lens between different foci of far and near vision. The invention also includes a sensor cell that directly interacts with the ciliary muscle contraction and relaxation to create changes in pressure between the accommodating cell chambers that results in changing surface relief structure height and the lens accommodation.

Abstract: A foldable accommodating intraocular lens (AIOL) for implantation in a human eye, the AIOL including a hollow flattened sphere shaped housing including a shape memory optical element and a tubular casing mounted on the housing for reciprocation relative thereto for selectively compressing the shape memory optical element between a non-compressed shape and a compressed shape whereby the AIOL has a continuously variable Diopter strength

Abstract: An intraocular lens for insertion into the capsular bag of an eye contains an optic, an outer periphery, and an outer support structure. The optic has a periphery and centered about an optical axis. The outer periphery is disposed about the optic and configured to engage an equatorial region of the capsular bag of an eye. The outer support structure is disposed along the periphery and spaced from the optic with voids outer support structure and the optic. The intraocular lens further comprises a first intermediate member and a weakened region disposed along the outer periphery between the outer support structure and the first intermediate member. The first intermediate member operably couples the optic and the outer support structure. The weakened region is attached to, and configured to provide relative motion between, the outer support structure and the first intermediate member in response to the ciliary muscle of the eye.

Abstract: An accommodating intraocular lens for providing a range of accommodative vision contains an optic and a haptic. The optic is disposed about an optical axis and includes an anterior surface and a posterior surface defining a clear aperture of the optic. The haptic is at least partially disposed inside the optic and includes an inner structure, an outer structure, and a plurality of arms disposed between and connecting the inner structure and the outer structure. The inner structure is circumferentially disposed about the optical axis, while the outer structure is circumferentially disposed about the inner structure and has an outer face. Each arm has proximal portion adjacent the inner structure and a distal portion adjacent the outer structure that is bifurcated in a radial direction from the proximal portion. The intraocular lens also has an outer surface defined by outer surfaces of the plurality of arms and an outer surface of the outer structure.

Abstract: Accommodating intraocular lenses containing a flowable media and their methods of accommodation.

Abstract: A method for modifying the refractive index of an optical polymeric material. The method comprises continuously irradiating predetermined regions of an optical, polymeric material with femtosecond laser pulses to form a gradient index refractive structure within the material. An optical device includes an optical, polymeric lens material having an anterior surface and posterior surface and an optical axis intersecting the surfaces and at least one laser-modified, GRIN layer disposed between the anterior surface and the posterior surface and arranged along a first axis 45° to 90° to the optical axis, and further characterized by a variation in index of refraction across at least one of at least a portion of the adjacent segments and along each segment.

Abstract: An accommodating intraocular lens has an anterior portion including an anterior viewing element and an anterior biasing element connected to the anterior viewing element. A posterior portion has a posterior viewing element and a posterior biasing element connected to the posterior viewing element. The anterior and posterior biasing elements are connected at first and second apices. First and second distending members are connected to the posterior portion. The first and second distending members extend to locations significantly anterior of an anterior side of the posterior viewing element.

Abstract: The invention relates to an intraocular accommodative lens, comprising an optical arrangement and haptics, the lens being adapted for variable focusing by movement of at least one part of the optical arrangement by at least one of the haptics, wherein the haptics comprise a part adapted to transfer a movement from the ciliary mass to the optical arrangement. This forms an attractive way of driving the variable lens, in particular for locations of the lens avoiding the capsular bag.

Abstract: Systems and their methods of use for testing intraocular lenses outside of the lens capsule. In some embodiments the systems measure an accommodative response based on a force applied to the intraocular lens.

Abstract: Methods and systems for obtaining an ocular aberration measurement of an eye of a patient are provided. Exemplary techniques involve obtaining a first induced metric for the eye that corresponds to a first accommodation state of the eye, obtaining a second induced metric for the eye that corresponds to a second accommodation state of the eye, and determining a natural metric of the eye based on the first and second induced metrics. An induced metric may include a pupil size or a spherical aberration. Techniques can also include determining a target metric for the eye base on the natural metric, determining whether an actual metric of the eye meets the target metric, obtaining an ocular aberration measurement of the eye if the actual metric meets the target metric, and determining a treatment for the eye based on the ocular aberration measurement.

Abstract: An intraocular lens includes a flexible capsule configured to be inserted into a natural lens capsular bag, a semisolid or solid portion disposed in the flexible capsule, the semisolid or solid material being adjustable so as to achieve emetropic refraction, and a polymeric gel disposed in the flexible capsule, the polymeric gel configured and arranged so as to be capable of providing accommodation.

Abstract: An accommodating intraocular lens has an anterior portion including an anterior viewing element and an anterior biasing element connected to the anterior viewing element. A posterior portion has a posterior viewing element and a posterior biasing element connected to the posterior viewing element. The anterior and posterior biasing elements are connected at first and second apices. First and second distending members are connected to the posterior portion. The first and second distending members extend to locations significantly anterior of an anterior side of the posterior viewing element.