Abstract: Intraocular implants and methods of making intraocular implants are provided. The intraocular implant can include a lens body having a lens material and a mask having a mask material. The lens body can be secured to the mask. The mask material can include a modulus of elasticity that is greater than or equal to a modulus of elasticity of the lens material.

Abstract: The present invention concerns a process for the production of implants with an ultrahydrophilic surface as well as the implants produced in that way and also processes for the production of loaded, so-called bioactive implant surfaces of metallic or ceramic materials, which are used for implants such as artificial bones, joints, dental implants or also very small implants, for example what are referred to as stents, as well as implants which are further produced in accordance with the processes and which as so-called “delivery devices” allow controlled liberation, for example by way of dissociation, of the bioactive molecules from the implant materials.

Abstract: An accommodating intraocular artificial lens with variable optical power, comprising two optical elements which are adapted to mutually shift in a direction perpendicular to the optical axis wherein the optical elements have such a shape that the optical elements exhibit, in combination, different optical powers at different relative positions. Flanges are adapted to position the anterior section of the haptics in the sulcus of the eye or, alternatively, the ciliary body is enclosed by a combination of anterior and posterior flanges. Also disclosed are methods to provide for an accommodating intraocular lens which is adjustable post-implant to ensure emmetropia of the eye.

Abstract: An accommodating intraocular lens (AIOL) comprising an optic, and at least one haptic plate coupled to the optic by at least one connector, the connector being less rigid than the haptic plate, the at least one haptic plate surrounding the optic, and the optic and haptic plate having a combined surface area between 70 mm2 and 100 mm2. The at least one haptic plate may form a continuous 360-degree boundary around the optic. The at least one haptic plate has a width in a radial dimension of 1.0-3.5 mm across its entire angular extent.

Abstract: An intraocular lens comprising a lens optic coupled to at least one haptic and at least one deformable connecting bar positioned between the lens optic and the at least one haptic.

Abstract: The present invention relates to a method of forming an insert for contact lens. The insert having rings and ring segments that make up functionalized layers in a functional layer insert, for incorporation into an ophthalmic lens. The layer insert which can include substrate layers that are intact full rings, segmented rings or a combination of both. The method includes the steps of forming the ring segments, assembling the ring segments into ring substrate layers, forming electrical interconnections and encapsulating the insert in a contact lens.

Abstract: A variable focus intraocular lens comprises an optic coupled to at least one haptic at a rigid flexion that sets a non-zero angle between the optic and the haptic.

Abstract: An accommodating intraocular lens (AIOL) comprising an optic, and at least one haptic plate coupled to the optic by at least one connector, the connector being less rigid than the haptic plate, the at least one haptic plate surrounding the optic, and the optic and haptic plate having a combined surface area between 70 mm2 and 100 mm2. The at least one haptic plate may form a continuous 360-degree boundary around the optic. The at least one haptic plate has a width in a radial dimension of 1.0-3.5 mm across its entire angular extent.

Abstract: A plate haptic for an accommodating intraocular lens. The plate haptic has a haptic body that is substantially rigid in a longitudinal direction and substantially flexible in a transverse direction. A chassis is integral to the haptic body. The chassis causes the haptic body to be substantially more rigid in a longitudinal direction than in a transverse direction.

Abstract: A plate haptic for an accommodating intraocular lens. The plate haptic has a haptic body that is substantially rigid in a longitudinal direction and substantially flexible in a transverse direction. A chassis is integral to the haptic body. The chassis causes the haptic body to be substantially more rigid in a longitudinal direction than in a transverse direction.

Abstract: An accommodating intraocular lens has a lens optic that is coupled to at least one haptic and is anteriorly biased with respect thereto.

Abstract: An exchangeable intraocular lens device having a flexible, high-memory expansile lens fixation platform adapted to receive the haptics of an intraocular lens, and their method of use, are provided. The device is specifically designed to expand completely into the equatorial fornix of the capsular bag and become permanently implanted therein. The design of the present invention addresses the desire of patients to exchange their existing intraocular lens to meet their changing visual needs or to take advantage of improved lens technology, without incurring the significant risks typically associated with exchange of current intraocular lens technology. The exchangeable intraocular lens device provides accurate centration, positioning, and stability of the intraocular lens in the capsular bag. The exchangeable intraocular lens device reduces lens epithelial cell migration and resultant posterior capsule opacification.

Abstract: An intraocular implant for placement in the eye, e.g. as part of a cataract operation or crystalline lens extraction refractive operation, has at a peripheral portion of the implant a groove which engages with the lip of a single capsulotomy only formed in the lens capsule of the eye. The implant will normally be a lens, but may instead be a bung or plug for occluding an opening made in the capsule. The groove may be a continuous groove around the periphery of the implant, or there may be a series of individual spaced-apart grooves formed as projections protruding from the periphery. Instead of a single groove, a pair of axially spaced-apart grooves may be provided, which engage with respective capsulotomies formed in an anterior and a posterior part of the capsule.

Abstract: Generally, an intraocular implant and methods for treating an ocular condition. In particular, an intraocular implant which implanted between an intraocular lens and the surface of the posterior capsule of the eye inhibits migration of residual lens epithelial cells after cataract surgery by providing structural barriers to reduce posterior capsule opacification of the eye.

Abstract: A variable focus intraocular lens comprises an optic coupled to at least one haptic at a flexion that sets a non-zero angle between the optic and the haptic.

Abstract: An intraocular lens comprises an optic and one or more haptics, wherein the or each haptic can be compressed in the plane of the lens, and which additionally comprises, around the optic, an annular rim that, in use, is in contact with the posterior capsular sac.

Abstract: An intraocular lens assembly for implantation in the posterior chamber of an eye has anchor portions with teeth rigid enough to penetrate the scleral wall of an eye. A method for implanting the lens includes the steps of: introducing the first haptic portion with a first anchor portion that includes a plurality of teeth projecting therefrom, into the posterior chamber of the eye until said teeth are anchored in the scleral wall at a desired location; and moving a second haptic portion with a plurality of teeth projecting therefrom, until said teeth are anchored in the scleral wall on the opposite side of the lens from the first anchor portion.

Abstract: An accommodating intraocular lens has a lens optic that is coupled to at least one haptic and is anteriorly biased with respect thereto.

Abstract: An accommodating artificial ocular lens (AAOL) device including a moving lens optic portion connected to a lens plate haptic portion. Preferably, the lens optic portion is connected to the lens plate haptic portion by a pair of flexible or resilient transverse oriented lens arm portions to provide or allow for movement of the lens optic portion.

Abstract: An accommodating intraocular lens comprising a flexible body, a flexible optic which is moveable anteriorly and posteriorly relative to the lens body, and hinged portions longitudinally connecting the optic to the body. The body may have extending centration and fixation loops on its distal ends.

Abstract: An accommodating intraocular lens comprising a flexible body, a flexible optic which is moveable anteriorly and posteriorly relative to the lens body, and a weakened portion connecting the optic to the body. The body may have extending centration and fixation loops on its distal ends.

Abstract: A plate haptic is used with an intraocular lens optic displaceable in response to vitreous pressure changes. The plate haptic comprises: a plurality of opposing lateral portions; a distal portion having a plurality of opposing projections extending substantially laterally therefrom; and a proximal portion comprising a strap across which is a hinge connecting the lens optic to the haptic. The intersection of the proximal portion with each lateral portion forms a plurality of appendages, or paddles, to partially surround the optic. The appendages, projections, and hinged straps combine to substantially aid displacement of the lens optic in response to changes in vitreous pressure.

Abstract: An intraocular lens for insertion into a capsular bag of an eye. A plurality of flexible connecting members couples a lens optic to a pair of opposing of plate haptics. The coupling members stabilize the optic with respect to the haptics. The coupling members are spaced apart straps having grooves that increase lens response to changes in vitreous pressure.

Abstract: A plate haptic for an accommodating intraocular lens. The plate haptic has a haptic body that is substantially rigid in a longitudinal direction and substantially flexible in a transverse direction. A chassis is integral to the haptic body. The chassis causes the haptic body to be substantially more rigid in a longitudinal direction than in a transverse direction.

Abstract: An intraocular lens assembly for increased depth of focus has a frame configurated to vault posteriorly in an eye and an optic attached thereto. Pressure from ciliary muscle contraction moves the optic anteriorly to focus the eye for near vision.

Abstract: A method of anchoring an accommodating intraocular lens assembly in the posterior chamber of an eye includes the steps of, (1) introducing the first haptic portion, which includes a first anchor portion projecting therefrom, into the posterior chamber of the eye until the first anchor portion is anchored in the scleral wall at a desired location; and (2) moving the second haptic portion, which comprises a second anchor portion projecting therefrom, until the second anchor portion is anchored in the scleral wall on the opposite side of the lens from the first anchor portion and the lens structure is in contact with the collapsed natural lens, whereby the collapsed natural lens capsule will be prestressed and deform the lens body relative to and substantially independently of the haptics element in relation to the force the capsular unit applies directly or indirectly to the lens body along the optical axis.

Abstract: An accommodating intraocular lens comprising an optic made from solid silicone and liquid silicone. The optic has a central anterior area or membrane that can vary in radius and thus charge power.

Abstract: An attachment plate for a haptics system for retaining an intraocular lens in a human eye having a visual axis and including a sclera of tough connective tissue, and an annular ciliary sulcus. The haptics system includes a longitudinal axis intended to be co-directional with the human eye's visual axis, a main body with at least two elongated haptics extending therefrom in opposite directions in a plane perpendicular to the longitudinal axis. Each of the elongated haptics has an attachment plate including (1) at least two pointed puncturing members, (2) each puncturing member terminating at a tip for penetrating the tough connective tissue of the human eye's sclera for self-anchoring implantation of the haptics system in the human eye's annular ciliary sulcus at least two spaced apart stationary anchor points, (3) the at least two pointed puncturing members having a minimum tip separation between their tips of at least 1 mm in said plane perpendicular to said longitudinal axis.

Abstract: An intraocular lens system for implantation in the human eye, haptic system and method include an intraocular lens formed of a transparent biocompatible material for replacing the natural lens of the eye. The lens includes an outer periphery and an optical axis. There is a haptic system for securely anchoring the intraocular lens in the posterior chamber of the eye. The haptic system includes at least two haptic portions formed of a rigid biocompatible material that are connected to and extend outwardly from the outer periphery the lens in a plane substantially perpendicular to the optical axis of the lens for holding the lens in the eye. Each haptic portion has an outer edge that is sized and shaped to extend from the lens to the scleral wall of the posterior chamber of the eye.

Abstract: An accommodating intraocular lens comprising a flexible body, a flexible optic which is moveable anteriorly and posteriorly relative to the lens body, and a weakened portion connecting the optic to the body. The body may have extending centration and fixation loops on its distal ends.

Abstract: An accommodating IOL comprises an optic adapted to focus light toward a retina of an eye, and a movement assembly coupled to the eye to provide effective accommodating movement, preferably axial movement, of the optic. At least a portion of the movement assembly is made from a material that is less stiff and/or more resilient than the material used to make the optic. Optionally, an outer ring or support portion made at least partially from either a relatively stiff material such as the material used in the optic or a relatively resilient material such as the material used in the movement assembly is also provided.

Abstract: An accommodating intraocular lens comprising a flexible body and flexible optic, and a flexible skirt connecting the optic to the body. The body may have extending loop haptics.

Abstract: Devices, methods and kits are described for reducing intraocular pressure. The devices include a support that is implantable within Schlemm's canal and maintains the patency of the canal without substantially interfering with transmural fluid flow across the canal. The devices utilize the natural drainage process of the eye and can be implanted with minimal trauma to the eye. Kits include a support and an introducer for implanting the support within Schlemm's canal. Methods include implanting a support within Schlemm's canal, wherein the support is capable of maintaining the patency of the canal without substantial interference with transmural fluid flow across the canal.

Abstract: An accommodating intraocular lens comprising a flexible body, a flexible optic which is moveable anteriorly and posteriorly relative to the lens body, and hinged portions longitudinally connecting the optic to the body. The body may have extending centration and fixation loops on its distal ends.

Abstract: The implant according to the invention is intended to be used as a replacement for an orbita bottom and optionally also for the medial orbita wall. The implant comprises the form of a single-piece preformed plate or grid which comprises a first segment, a second segment and a third segment. The first segment is designed in accordance with the form of the orbita bottom and the second segment is designed according to the form of the medial side-wall. The first and second segments adjoin each other along a first preset breaking line. The third segment adjoins the first segment and is arranged for fixing the implant to the lateral orbita edge.

Abstract: An anterior chamber phakic lens made from a foldable, highly biocompatible material that has a very low haptic compression force and low axial displacement, yet is stable in the anterior chamber.

Abstract: An accommodating intraocular lens having an optic and portions extending from the optic radially outwards preferably with fixation devices at their distal ends, the optic designed such that it has a sharp posterior edge for 360 degrees of its perimeter and the lens designed such that the optic can move forward and backwards with constriction and relaxation of the ciliary muscle.

Abstract: Intraocular lenses for implanting within the natural capsular bag of the human eye having features on the outer ends or portions of the lenses to fixate the lens within the natural capsular bag following implantation.

Abstract: An accommodating intraocular lens device including a lens portion connected to a plate haptic portion. Preferably, the lens portion is connected to the plate haptic portion by a pair of flexible or resilient arms.

Abstract: Intraocular lenses for implanting within the natural capsular bag of the human eye having features on the outer ends or portions of the lenses to fixate the lens within the natural capsular bag following implantation.

Abstract: The present invention relates to a first intraocular lens (120) embodiment having a retainer plate (124) with an annular region surrounding a central opening and an optical lens (122) removably attached to the retainer plate within the central opening. Also disclosed is a second intraocular lens embodiment having a retainer plate with a porous or perforated annular region surrounding a central opening. An optical lens (122) is integral with the retainer plate (124) within the central opening. Methods of implanting these intraocular lens (120) embodiments into a patient's eye are disclosed. Also described here are methods of replacing the first intraocular lens embodiment after it has been implanted in a patient's eye.

Abstract: An accommodating intraocular lens where the optic is moveable relative to the outer ends of the extended portions. The lens comprises an optic made from a flexible material combined with haptics capable of multiple flexions without breaking. The haptics are narrow adjacent the optic and wider at their outer ends. The haptics have wide and deep hinges adjacent the optic to better allow the hinges to “stretch” somewhat.

Abstract: An accommodative intraocular lens (AIOL) adapted to fit in a capsular bag, having an optic; at least three haptic arms, each arm being coupled to the optic along the arm's length and at least three plates, each plate having an outer surface arranged to contact the capsular bag and each plate being coupled to at least two of the haptic arms, the coupling with each arm occurring at a connection. The haptic arms and plates, in combination, may be arranged to form a closed figure surrounding the optic. A first area of the outer surface of at least one of the plates may be disposed anteriorly of a centroid of the connection with at least one of the plates, and a second area of the outer surface of the at least one of the plates being disposed posteriorly of the centroid, the first area and the second area being within 200% of one another in magnitude.

Abstract: A two-optic accommodative lens system. The first lens has a negative power and is located posteriorly within the capsular bag and laying against the posterior capsule. The periphery of the first lens contains a pair of generally T-shaped haptics oriented along a vertical meridian of the capsular bag and having a generally rectangular slot within the top portion of the “T”. The first lens further having a plurality of elongated haptics oriented along a horizontal meridian of the capsular bag. The second lens is located anteriorly to the first lens outside of the capsular bag and is of a positive power. The peripheral edge of the second lens contains a pair of encircling haptics having a notched tab sized and shape to fit within the slots in the haptics on the first lens to lock the second lens onto the first lens. Hinge structures on the encircling haptics allow the second lens to move relative to the first lens along the optical axis of the lens system in reaction to movement of the ciliary muscle.

Abstract: An accommodating lens assembly having an optical axis and being adapted to be implanted in a posterior chamber of an eye having a capsular unit located therein. The assembly includes a rigid haptics element adapted to secure the assembly within the posterior chamber outside said capsular unit. The element is transparent at least in a region around the axis. The assembly further includes a resilient body adapted to operate as a lens having a curved surface when pressed up against the region of the haptics element by an axial force applied thereto by the capsular unit. A change in this force causes a change in a radius of curvature for the curved surface.

Abstract: An intraocular lens structure for reducing complications is disclosed. The intraocular lens structure comprises an optic, a support and a closing fixture. The closing fixture is a groove or a valley formed on the side portion of the optic of the intraocular lens. The valley is formed by the optic and a protrusion projecting posteriorly from the optic. The groove or the valley in the optic is made engaged with the posterior capsular opening generally over the entire circumference of the groove or the valley to close the opening of the posterior capsule.

Abstract: An intraocular lens assembly for increased depth of focus has a frame configurated to vault posteriorly in an eye and an optic attached thereto. Pressure from ciliary muscle contraction moves the optic anteriorly to focus the eye for near vision.

Abstract: A flexible accommodating intraocular lens having anteriorly and posteriorly movable extended portions, such as T-shaped haptics, extending from a central solid biconvex optic to be implanted within a natural capsular bag of a human eye with the extended portions positioned between an anterior capsular rim and a posterior capsule of the bag, whereby during a post-operative healing period, fibrosis occurs about the extended portions to fixate the lens in the bag in a manner such that subsequent natural contraction and relaxation of the ciliary muscle moves the optic to provide vision accommodation. A surface of the optic is a toric surface.

Abstract: A two-optic accommodative lens system. The first lens has a negative power and is located posteriorly within the capsular bag and lying against the posterior capsule. The periphery of the first optic contains a plurality of generally T-shaped haptics. The overall diameter of the first optic is slightly smaller than the capsular bag. The second optic is located anteriorly to the first optic outside of the capsular bag and is of a positive power. The peripheral edge of the second optic contains a plurality of generally T-shaped haptics and the second optic is slightly larger in overall diameter that the first optic. The haptics allow the second optic to move relative to the first optic along the optical axis of the lens system in reaction to movement of the ciliary muscle and corresponding shrinkage of the capsular bag.

Abstract: An accommodating lens assembly having an optical axis and being adapted to be implanted in a posterior chamber of an eye having a capsular unit located therein. The assembly comprises a rigid haptics element adapted to secure the assembly within the posterior chamber outside said capsular unit. The element is transparent at least in a region around the axis. The assembly further comprises a resilient body adapted to operate as a lens having a curved surface when pressed up against the region of the haptics element by an axial force applied thereto by the capsular unit. A change in this force causes a change in a radius of curvature for the curved surface.