Patents Represented by Attorney, Agent or Law Firm A. Kate Huffman
  • Patent number: 4844085
    Abstract: A method and a device for measuring mechanical property parameters of the pulmonary system of a patient which comprises;inflating and deflating the lung with a predetermined gas volume with a pump;measuring the pressure changes generated in the lung during inflation and deflation with a pressure sensor;transforming the volume and the measured pressure data into digital form;calculating typical or clinically significant volume to pressure ratios in a data processor and;displaying the result of the calculation.
    Type: Grant
    Filed: November 14, 1988
    Date of Patent: July 4, 1989
    Inventor: Luciano Gattinoni
  • Patent number: 4833774
    Abstract: A transparent disk with a round periphery is produced, for example, by a grinding operation, and a mark is placed at the geometric center of the disk. A coil is then wound about the periphery of the disk. As a consequence, the mark at the geometric center of the disk coincides with the electrical center point of the coil, thus obviating the need for a bobbin, or coil former, on which the coil can be wound.The transparent disk is first ground into a round shape, and a metallic film is deposited on a surface of the disk. The film is coated with a photosensitive resist material, and then exposed through a mask to define an image of a mark at the geometric center of the disk. The film is then etched to remove all but the mark from the disk.In manufacturing the coil, the disk, is concentrically clamped between two plates of a winding jig, each plate having annular peripheral flanges that are radially larger than the disk and thus project beyond the periphery of the disk.
    Type: Grant
    Filed: December 10, 1987
    Date of Patent: May 30, 1989
    Assignee: Kontron Holding A.G.
    Inventors: Wolfgang Jacob-Grinschgl, Udo Muller
  • Patent number: 4808630
    Abstract: This invention is directed towards methods for treating patients having a psychotic illness such as schizophrenia and/or inhibiting the occurrence of movement disorders in patients receiving or having received a neuroleptic medication by administering to the patients a pharmaceutically effective amount of a retinoid, such as retinoic acid, and particularly isotretinoin.
    Type: Grant
    Filed: February 16, 1988
    Date of Patent: February 28, 1989
    Assignee: United States of America
    Inventor: Gregory M. Straw
  • Patent number: 4805821
    Abstract: An ampule opener is provided for automatically opening ampules. The ampule opener is especially suitable for use in a robotic sterility test system and is provided with a pneumatic actuator means releasably connected to an ampule opener arm. The head of an ampule is positioned with its neck on a knife edge so that when the ampule opener arm is rotated by the actuator means, the arm applies a pressure on the head of the ampule and the ampule head drops away.
    Type: Grant
    Filed: August 14, 1987
    Date of Patent: February 21, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Ludwik Kowalczyk, Gilbert C. Kaetzel
  • Patent number: 4801584
    Abstract: The invention is concerned with tricyclic compounds of the formula ##STR1## wherein R.sup.1 is a hydrogen atom or a carboxy-protecting radical; R.sup.2 is a hydrogen atom or a lower alkyl radical which may be substituted with a halogen atom; R.sup.3 and R.sup.4 independently are a hydrogen atom or a lower alkyl radical which may be substituted with a hydroxy radical or a substituted or unsubstituted amino radical; X is a halogen atom; and R.sup.5 and R.sup.6 are independently a hydrogen atom or a lower alkyl radical which may be substituted with a hydroxy radical, a lower alkoxy radical or a substituted or unsubstituted amino radical; or R.sup.5 and R.sup.6, taken together with the adjacent nitrogen atom, may form a 5 to 7 membered heterocyclic ring which may be substituted with one or more substituents at the carbon atom(s), and the heterocyclic ring may further contain --NR.sup.7 --, --O--, --S--, --SO--, --SO.sub.2 -- or --NR.sup.7 --CO--, and also R.sup.
    Type: Grant
    Filed: September 8, 1987
    Date of Patent: January 31, 1989
    Assignee: Hoffmann-La Roche Inc.
    Inventors: Kazuteru Yokose, Nobuo Shimma, Miyako Kamata, Masahiro Aoki, Tatsuo Ohtsuka