Abstract: A method of registering a note with a governmental authority including filing a prospectus supplement including detailed descriptions of a plurality of asset classes and a plurality of transaction structures and incorporating by reference a base prospectus, wherein the base prospectus includes an identification of one or more types of securities available from an issuer of the note and characteristics of the issuer.

Abstract: Provided are aluminum chelates having the formula (I). Also provided are compositions having these chelates, methods of producing these chelates, and methods of modifying the viscosity of a liquid or a semisolid using these chelates.

Abstract: The present invention relates to neurological and physiological dysfunction associated with neuron disorders. In particular, the invention relates to the involvement of vascular endothelial growth factor (VEGF) and homologues in the aetiology of motor neuron disorders. The invention further concerns a novel, mutant transgenic mouse (VEGFm/m) with a homozygous deletion in the hypoxia responsive element (HRE) of the VEGF promoter which alters the hypoxic upregulation of VEGF. These mice suffer severe adult onset muscle weakness due to progressive spinal motor neuron degeneration which is reminiscent of amyotrophic lateral sclerosis (ALS)—a fatal disorder with unknown aetiology. Furthermore, the neuropathy of these mice is not caused by vascular defects, but is due to defective VEGF-mediated survival signals to motor neurons.

Abstract: Provided is an isolated and purified DNA molecule comprising the coding region of a PCFT cDNA. Also provided is a segment of the above DNA molecule, capable of serving as a primer for amplifying at least a portion of the DNA molecule. Additionally provided is a pair of the above segments that can be used together as forward and reverse PCR primers for amplifying at least a portion of the above DNA molecule. Further provided is an isolated and purified human PCFT protein. Also provided is a method of evaluating the ability of a human to undergo intestinal folate absorption.

Abstract: The present invention relates to methods of treating the underlying dysregulation of the emotional functionality of mental disorders (i.e. affect instability—hypersensitivity—hyperaesthesia—dissociative phenomena—. . . ) using compounds and compositions of compounds having D4 and/or 5-HT2A antagonistic, partial agonistic or inverse agonistic activity. The invention also relates to methods comprising administering to a patient diagnosed as having a neuropsychiatric disorder a pharmaceutical composition containing (i) compounds having D4 antagonistic, partial agonistic or inverse agonistic activity and/or (ii) compounds having 5-HT2A antagonistic, partial agonistic or inverse agonistic, and/or (iii) any known medicinal compound and compositions of said compounds. The combined D4 and 5-HT2A antagonistic, partial agonistic or inverse agonistic effects may reside within the same chemical or biological compound or in two different chemical and/or biological compounds.

Abstract: A disposable absorbent article with an associated polymer film that is positioned to be activated by contact with bodily fluids, wherein the polymer film can release odor control and/or skin wellness agents upon contact with such bodily fluids. The polymer film can release the odor control and/or skin wellness agents immediately, gradually over a period of time after contact with such bodily fluids, or a combination of both. The polymer film can also be used for household cleaning applications, in which the polymer film can similarly contain and subsequently release household cleaning agents upon contact with water.

Abstract: Absorbent articles suitable for use as diapers or other hygiene products are provided. The absorbent articles have one or more closure system features including dual elasticity, rear closure, and the use of co-adhesives for the fasteners. Products according to the invention may provide any of several benefits, including a high level of comfort in use, resistance to tampering by the wearer, and relatively quiet attachment and detachment of the closures.

Abstract: A system for generating electricity including a vertical oriented tower comprising an intake opening for receiving fluid flow, a scoop that is moveably mounted to a base for directing the fluid flow to the intake opening, a fluid-activated mechanism that is automatically oriented in response to direction of the fluid flow, the fluid-activated mechanism being operatively connected to the scoop so that orientation of the fluid-activated mechanism in response to the fluid flow angles the scoop in the direction of the fluid flow, and a turbine that receives the fluid flow directed by the scoop to generate electricity.

Abstract: A method of generating electricity including the steps of providing a system including a vertical oriented tower having an intake opening, a scoop that is moveably mounted to a base, the scoop being in fluid communication with the intake opening of the tower, a fluid-activated mechanism that is automatically oriented in response to direction of fluid flow, the fluid-activated mechanism being operatively connected to the scoop so that orientation of the fluid-activated mechanism in response to the fluid flow angles the scoop in the direction of the fluid flow, and one or more turbines that receive the fluid flow directed by the scoop to generate electricity. The fluid-activated mechanism is oriented in response to the fluid flow. The scoop is angled based on the oriented fluid-activated mechanism so that the fluid flows into the scoop. The fluid is directed through the scoop into the intake opening of the tower and through the tower towards the one or more turbines for generation of electricity.

Abstract: A rollator having a variable track width that can be adjusted across a range of widths for use in operation by pivoting a pair of support members, wherein the alignment of the wheels is maintained in the direction of travel during operation across the range of track widths.

Abstract: Provided are non-human mammals treated with doxorubicin, lipopolysaccharide (LPS), and p-chlorophenylalanine (PCPA), where the mammal exhibits a symptom characteristic of infantile spasms. Also provided are methods of making a non-human mammal exhibit a symptom of infantile spasms. Additionally, methods are provided for screening a compound for the potential to attenuate a symptom of infantile spasms.

Abstract: A hydroengorged spunmelt nonwoven formed of thermoplastic continuous fibers and a pattern of fusion bonds. The nonwoven has either a percentage bond area of less than 10 percent, or a percentage bond area of at least 10% wherein the pattern of fusion bonds is anisotropic.

Abstract: The present invention relates to methods of treating of the underlying dysregulation of the emotional functionality of mental disorders (i.e. affect instability-hypersensitivity-hyperaesthesia-dissociative phenomena- . . . ) using compounds and compositions of compounds having D4 and/or 5-HT2A antagonistic, partial agonistic or inverse agonistic activity for. The invention also relates to methods comprising administering to a patient diagnosed as having a neuropsychiatric disorder a pharmaceutical composition containing (i) compounds having D4 antagonistic, partial agonistic or inverse agonistic activity and/or (ii) compounds having 5-HT2A antagonistic, partial agonistic or inverse agonistic, and/or (iii) any known medicinal compound and compositions of said compounds. The combined D4 and 5-HT2A antagonistic, partial agonistic or inverse agonistic effects may reside within the same chemical or biological compound or in two different chemical and/or biological compounds.

Abstract: A method of measuring a quantity of a substrate contained in sample liquid is provided. This method can reduce measurement errors caused by a biosensor. The biosensor includes at least a pair of electrodes on an insulating board and is inserted into a measuring device which includes a supporting section for supporting detachably the biosensor, plural connecting terminals to be coupled to the respective electrodes, and a driving power supply which applies a voltage to the respective electrodes via the connecting terminals. One of the electrodes of the biosensor is connected to the first and second connecting terminals of the measuring device only when the biosensor is inserted into the measuring device in a given direction, and has a structure such that the electrode becomes conductive between the first and second connecting terminals due to a voltage application by the driving power supply.

Abstract: A diving stick of the type that, after being tossed into a swimming pool, sinks to the bottom while maintaining an upright posture so that it be can easily grasped by a diver. The stick includes a soft hollow shank designed to prevent accidental impalement.

Abstract: A secure photomask including a substrate having one or more pattern layers formed thereon and a blocking aperture disposed below the one or more pattern layers that prevents at least one of unauthorized use and copying of the photomask.