Abstract: An apparatus (10) for monitoring the position of an eye during a laser ablation treatment of the eye is provided. The apparatus includes optic means (110) for directing an incident light beam (102) along an optical path (104) onto the external surface of the eye (35) so as to illuminate a region of said surface that includes a segment of the limbus of the eye, and for directing back along said optical path (104), a return beam (122) comprising light of said incident beam scattered by said surface region; beam separation means (125) for separating the return beam (122) from the incident beam (102). The apparatus also includes at least one detector (120), having one or more detector segments (120a, 120b), for detecting said return beam (122), said detector segment(s) (120a, 120b) recording first and second values for light scattered respectively by the sclera and iris in said illuminated region.

Abstract: The invention presents a total knee arthroplasty endoprosthesis having: a) a femoral component with a lower-radius lateral condyle, a larger-radius medial condyle and between them, a third condyle located posteriorly, superiorly and nearest the medial side, b) a tibial component with a central protruding spigot for the rotating polyethylene insert, and c) a rotating polyethylene insert, with three cavities for articulation of the femoral condyles. For initial and moderate flexion the joint functions with load bearing onto the lateral and medial articular cavities, and in advanced and final flexion with load bearing on the third articular cavity. The advantages of this endoprosthesis are enhanced maximum flexion, improved femoral axis alignment, significant posterior stabilization, favourable accommodation of tibial rotation with consequent relief of materials and fixations, and preservation of more articular fluid for lubrication and reduction of polyethylene wear.

Abstract: The invention relates to the determination of the anesthetic state of a patient. In order to achieve a mechanism that enables establishment and maintenance of balanced anesthesia, values are established for a set of diagnostic indices. The set includes at least two diagnostic indices of which a first diagnostic index is indicative of the level of hypnosis and a second diagnostic index of the level of nociception in the patient. The combination of the at least two index values obtained is employed for indicating the anesthetic state of the patient. The combination of the at least two index values may further be employed to control the administration of drugs to the patient.

Abstract: An actuator arrangement comprises a plurality of linearly extendable actuators arranged to be driven by a common electrically driven motor, each actuator, being provided with limit stops to limit extension and/or retraction thereof, wherein the limit stops of the actuators are positioned such that a first one of the actuators has a smaller range of permitted extension than at least a second one of the actuators.

Abstract: The present disclosure demonstrates the successful use of constitutive promoters operatively linked to genes encoding radiosensitizing or radioprotecting factors, administered to cells, tissues, or patients in conjunction with radiation exposure. Also disclosed are pharmacological preparations to be used to increase the levels of radiosensitizing compounds such as TNF-?, or radioprotective compounds such as MnSOD, in specified tissues or tumors of a subject.

Abstract: Systems and methods for controlling an alarm state, such as volume, based on the presence or absence of a caregiver in a patient's room. More specifically, a local sound producing device provides an audible alarm within a room when a caregiver is in the room, while a remote sound producing device provides an audible alarm external of the room when the caregiver is not in the room. Accordingly, volume levels of the sound producing devices depend on the sensed presence or absence of the caregiver within the room. For example, when the caregiver leaves the room, the local sound producing device is deactivated and/or the remote sound producing device is activated, thereby allowing the patient to enjoy a more relaxed environment within the room, yet still continue to be monitored.

Abstract: A method for identifying an occlusion in a breathing tube of a ventilator system is disclosed herein. The method includes obtaining data related to a respiratory signal, transferring the data to a processor, and implementing the processor to evaluate the data in a manner adapted to automatically identify the presence of an occlusion in the breathing tube. A corresponding ventilator system is also disclosed.

Abstract: Acid-neutralizing filter media includes filter media fibers in combination with a strong base of small particle size and high surface area attached to and immobilized on the filter media fibers, and methodology therefore.

Abstract: A method for minimizing tracking system interference caused by a motor driven ultrasonic imaging device is disclosed herein. The method includes providing an ultrasonic imaging device adapted to obtain a generally real time three-dimensional image. The ultrasonic imaging device includes a motor configured to rotate a transducer array within a catheter housing. The method for minimizing tracking system interference also includes estimating a noise signal produced by the motor, selecting a tracking system signal strength and/or frequency adapted to minimize a tracking system interference, and implementing a field generator to produce a tracking system signal at the selected tracking system signal strength and/or frequency.

Abstract: A vivarium cover locking clip prevents removal of a cover from a vivarium tank. The clip includes first and second brackets matingly engaging each other in a detent locked position and respectively engaging the cover and the tank and preventing separation thereof. The brackets have a released position permitting separation of the cover and the tank.

Abstract: A locker that may either be opened in a keyed or keyless manner includes a locking mechanism formed predominantly of sheet components. The locking mechanism is designed to be carried by the frame of the locker, and is particularly suited to enable the locker to be used as an evidence locker or similar restricted access storage compartment. Various spring biases are used to force the locking mechanism to a locked position when the locking mechanism is appropriately triggered, such as by a pushbutton. The locking mechanism is designed to be substantially tamper proof and cannot be reset to an unlocked position without a key, if equipped, or access to a lock resetting lever arm that is only accessible through a rear opening of the locker.

Abstract: A shaped charge includes: a charge case; an explosive disposed inside the charge case; and a liner for retaining the explosive in the charge case, wherein the liner is fabricated from a material soluble with a selected dissolving fluid (e.g., an acid, an acid matrix, an injection fluid, a completion fluid, and/or a wellbore fluid). A method for perforating in a well includes the steps of: disposing a perforating gun in the well, wherein the perforating gun comprises a shaped charge having a charge case, an explosive disposed inside the charge case, and a liner for retaining the explosive in the charge case, wherein the liner is fabricated from a material soluble with a selected dissolving fluid; detonating the shaped charge to form a perforation tunnel in a formation zone; and exposing the material comprising the liner to the selected dissolving fluid.

Abstract: Disclosed are sequences encoding monomeric variants of DsRed fluorescent proteins and methods of use.

Abstract: The system and method of the present application is a microfluidic array system for biological, chemical and biochemical assessments including a microfluidic chip for reaction assays, wherein the microfluidic chip includes a control layer and a fluidic layer, wherein the control layer is pressurized through pneumatic or hydraulic means in order to control the flow of the reagents in the fluidic layer. The system and method of the present application further includes a method of fabricating such a microfluidic chip, and further a method for operating the same. Lastly, the system and method of the present application further includes a system for operating and analyzing the microfluidic array including a pressure source, a fluidic source, a biochip reader, and a processor configured to control the same.

Abstract: A cardiac monitoring system is disclosed herein. The cardiac monitoring system includes a sensor adapted to collect an ECG signal that comprises a pacemaker signal and a cardiac signal. The cardiac monitoring system also includes a data acquisition module adapted to receive the ECG signal from the sensor. The data acquisition module includes a signal path adapted to isolate the pacemaker signal from the remainder of the ECG signal, and a processor adapted to identify a pace pulse on the isolated pacemaker signal.

Abstract: Selected surfaces of a cellular polymeric foam surface finishing pad are heated to cause the surface cells to partially collapse or to fully collapse and glaze over. The selected surfaces may be the planar pad faces or may be formed in one or more depressions formed in the planar faces. The areas of partially collapsed cell structures in the operating face of the pad provide a slow down in the rate of polish or compound absorption, increasing the effectiveness of the finishing process. The fully collapsed cell glazed surface on the rear attachment face of the pad prevents the migration of moisture through the pad to the pad attachment mechanism.

Abstract: A monitoring system and method for monitoring signals from an implantable medical device are disclosed. The monitoring system and method include a monitor configured to detect a radio frequency artifact from the signals of the implantable medical device and circuitry for processing the radio frequency artifact from the signals of the implantable medical device.

Abstract: Disclosed are compositions and methods related to powder and granular emulsifiable concentrate pesticide formulations. As disclosed, emulsions from non-aqueous based liquid or solvent soluble pesticide actives may be prepared using a high purity, high molecular weight sulfonated lignin as the emulsion stabilizer. The resulting emulsions may then be dried to obtain a powder or granular emulsion concentrate where the high molecular weight sulfonated lignin acts as a solid matrix for the pesticide active. The powder or granular emulsifiable concentrate formulations thus formed have high loading rates, good storage properties and are easily reconstituted when added to water.

Abstract: A molded plastic container, such as a five gallon pail, that includes a lid and main body that are selectively attachable to each other without a resilient gasket. The main body of the plastic container includes a flexible sealing finger formed along the top rim of the main body. The flexible sealing finger is received within a sealing chamber formed as part of the rim. The sealing chamber is defined by a gland seal such that when the lid is attached to the main body, both the flexible finger and the gland seal can deflect to create multiple sealing points between the flexible sealing finger and the sealing chamber. A latch ring is formed on the outer surface of the main body and engages a locking tab formed on the lid to hold the flexible finger in the sealing chamber.

Abstract: A filter element has a resiliently compressible end cap at a first axial end sealing the filter and providing sealed engagement with a flow tube. A filter assembly comprising a filter media element having a first end and a second end, a first end cap disposed at the first end, and a second end cap disposed at the second end. The filter media element is shaped to form a hollow interior extending from the first end to the second end. The hollow interior defines an inner boundary of the element and the outer surface of the element defines an outer boundary. The second end cap covers both the filter media element and the hollow interior at the second end.