Abstract: Compositions containing controlled amounts of d-fenfluramine are administered to block the intermittent carbohydrate cravings without necessarily suppressing other food intakes.

Abstract: A method of and apparatus for continuously removing dispersed particles which can be flocculated from a liquid containing said particles, such as wastewaters, wherein flocculation of said particles is caused to take place in a turbulent pipe flow by the injection and rapid mixing of a coagulant and/or coagulant aid in said turbulent pipe flow which simultaneously flocculates said particles and transports the mixture of flocculated particles and liquid into a settling tank for clarification. A controlled quantity of dispersed floc from said settling tank is continuously recirculated into said pipe flow at a station where mixing of the coagulant and/or coagulant aid is achieved, so as to reduce the length of said pipe to a desired size and the flow rate of said injected coagulant and/or coagulant aid.

Abstract: Steel is made from iron ore by comminuting the ore and recovering a particle fraction which has a size less than 50 microns. The iron rich particles then are reduced to form iron or magnetite and are beneficiated by magnetic separation. The magnetite particles are further reduced to form small size iron particles. The iron powders produced by these processes are then processed by powder metallurgical techniques.

Abstract: A cell-free process for converting isopenicillin N, .delta.-(L-.alpha.-aminoadipyl)-L-cysteinyl-D-valine (hereinafter "LLD") and 6-substituted derivatives thereof to deacetoxycephalosporin C (DACPC) by the following reaction sequence: ##STR1## is disclosed. In addition to the starting material, the reaction system includes ATP and a fresh extract of Cephalosporium acremonium prepared and used in a manner to preserve the racemase agent or agents necessary for conversion of the isopenicillin N to penicillin N, a necessary intermediate step in the process.

Abstract: A system for inactivation of microorganisms and their products (viruses, bacteria, toxins and cells) such as, for example, Herpes simplex viruses by superposition of a component such as, for example, methylene blue (MB) plus light, oxygen and electricity. The system serves to generate the superoxide radical anion (O.sub.2) and consequently hydrogen peroxide (H.sub.2 O.sub.2) and the hydroxyl radical (OH.), both of which enter into the inactivation process, but each has use beyond said system. The disclosed activating components include methylene blue covalently bonded to conconavalin A to enhance its binding to mammalian lymphoblasts and compounds of d.sup.- and f.sup.- transition metals such as cis-platinum diamino dichloride.

Abstract: A system to achieve heterodyne detection of optical (i.e., infrared, visible and ultraviolet) signal wavefront is disclosed. The system employs a holographic phase grating that, when illuminated by laser radiation, will generate a plurality of wavefronts each of which has a predetermined spatial distribution of amplitude and phase. The grating is part of an optical local oscillator that includes a laser that illuminates the holographic phase grating.

Abstract: A method of producing transplantable sheets of living keratinous tissue by culturing keratinocytes in a culture vessel and subsequently enzymatically detaching a sheet of keratinous tissue employing an enzyme, such as Dispase, is disclosed herein.

Abstract: Disclosed is a wind power generating apparatus for producing megawatt levels of power. The apparatus comprises at least one endless flexible cable supported on the peripheries of two spaced apart wheels. Airfoils are attached to the cable and disposed for generating aerodynamic forces which cause the cable and supporting wheels to turn allowing for the generation of power.

Abstract: An assay is disclosed for determining mutagenic damage caused by the administration of a known or suspected mutagen to diploid human lymphoblastoid cell lines. The gene locus employed for this assay is the gene for thymidine kinase, uridine kinase, or cytidine deaminase. Since human lymphoblastoid cells contain two genes for these enzymes, heterozygotes of human lymphoblastoid cells are used in this assay.

Abstract: An assay is disclosed for determining mutagenic damage caused by the administration of a known or suspected mutagen to bacterial cells such as Salmonella typhimurium. After administration of or exposure to a mutagenic agent, the bacterial cells are plated in the presence of a purine analog and resistance to purine analogs is used as the genetic marker. This bioassay system can be used by genetic toxicologists to determine the potential genetic hazards from the use of a variety of suspected or known mutagens, including newly-developed chemicals.

Abstract: An infrared radar system. The system includes an infrared laser and associated controller which are adapted to provide a succession of transmit pulses having a relatively high intensity spike portion followed by a relatively low intensity quasi-CW portion. An optical system directs the transmit pulses to a target scene and collects infrared radiation reflected from the scene. The collected radiation is imaged on a heterodyne detector array together with a locally generated reference infrared beam. A range network is responsive to signals from the detector array to provide signals representative of the range of objects in the target scene. A moving target indicator network is responsive to signals from the detector to provide signals representative of the velocity of objects in the target scene.

Abstract: A method and an apparatus for selectively summing the time-varying components of a plurality of electrical voltages are disclosed. The electrical voltages can each be characterized by a quiescent bias component and a time-varying small signal information component. Each electrical voltage is selectively connected to at most one of a plurality of summing buses and each bus is allowed to separately float to a quiescent voltage level corresponding approximately to a selected average value of the bias components of the signals connected thereto. The potential difference measured between the buses corresponds to the difference in the weighted average values of the time-varying components connected to each bus. The weights may be equal or unequal. The method and apparatus provide means for implementing programmable transversal filters and correlation devices.

Abstract: Blood pressure in animals is reduced by administering 2-chloro-6-methylergoline-8.beta.-acetonitrile (lergotrile*) or pharmaceutically acceptable salts thereof either alone or in combination with a substance which is known to reduce blood pressure. A novel composition is provided comprising a unit dosage form of lergotrile and a substance which is known to reduce blood pressure.(* The term "lergotrile" is intended to include the compound lergotrile as well as its physiologically- and pharmacologically-active metabolites in the body.

Abstract: Metal compositions having significantly improved mechanical properties and substantially free of second phase material are produced by heating a metal alloy from the non-equilibrium solidus temperature while subjecting the liquid-solid mixture to high pressure and forcing the liquid through a filter. The solid is rapidly quenched to retain solutes in solid solution or the solid is heat treated to permit solution of remaining secondary phase material followed by rapidly quenching the heat treated alloy. The solid then is re-heat treated at low temperature to permit age hardening. If the material is to be used in wrought form, it may be worked at any stage of the processing after interdendritic liquid is removed.

Abstract: Blood pressure in animals is reduced by administering tyrosine, a tyrosine precursor, tryptophan or mixtures thereof, either alone or in combination with a substance which is known to reduce blood pressure. A novel composition is provided comprising a unit dosage form of tyrosine, a precursor for tyrosine, tryptophan or mixtures thereof and a substance which is known to reduce blood pressure.

Abstract: Improved cell culture microcarriers, and methods for their production and use, are disclosed herein. These improved microcarriers have positive charge capacities adjusted and/or controlled within a range suitable for good cell growth. One method for producing such improved microcarriers is by treating beads formed from polymers containing pendant hydroxy groups, such as dextran beads, with an aqueous solution of an alkaline material and a chloro- or bromo-substituted tertiary amine under precisely controlled conditions to produce the desired exchange capacity. The resultant positively charged microcarriers have been used in microcarrier cultures to produce outstanding growth of anchorage-dependent cells. Such cells can be harvested, or used for the production of viruses, vaccines, hormones, interferon or other cellular growth by-products.

Abstract: A storage/logic array (SLA). In a programmable form (PSLA), the array includes a set of parallel, programmably segmentable column conductors and an orthogonal set of programmably segmentable row conductors. Each of a plurality of cell networks is associated with and coupled to a subset of the row conductors and a subset of the column conductors. At least one column conductor subset has an associated cell network which includes a storage element which is coupled to the associated column subset and row subset for that cell network. In a nonprogrammable form, the SLA is similar to the programmable form (PSLA) except that row and column conductors are segmented at predetermined locations, and cell networks are coupled to predetermined, associated subsets of the row and column conductors.

Abstract: An atomic beam is excited by laser radiation to a state with large principal quantum number. The beam is irradiated with infrared or millimeter wave radiation which is to be detected. The atoms absorb the radiation by making transitions to higher-lying states. The transitions are sensed by applying an electric field which ionizes atoms in the final state, but not the initial state. The ions ae collected and detected by conventional pulse-counting or direct current methods.

Abstract: A system for generating steady state confining current for a toroidal plasma fusion reactor providing steady-state generation of the thermonuclear power. A dense, hot toroidal plasma is initially prepared with a confining magnetic field with toroidal and poloidal components. Continuous wave RF energy is injected into said plasma to establish a spectrum of traveling waves in the plasma, where the traveling waves have momentum components substantially either all parallel, or all anti-parallel to the confining magnetic field. The injected RF energy is phased to couple to said traveling waves with both a phase velocity component and a wave momentum component in the direction of the plasma traveling wave components. The injected RF energy has a predetermined spectrum selected so that said traveling waves couple to plasma electrons having velocities in a predetermined range .DELTA.. The velocities in the range are substantially greater than the thermal electron velocity of the plasma.

Abstract: A system for generating steady state confining current for a toroidal plasma fusion reactor providing steady-state generation of the thermonuclear power. A dense, hot toroidal plasma is initially prepared with a confining magnetic field with toroidal and poloidal components. Continuous wave RF energy is injected into said plasma to estalish a spectrum of traveling waves in the plasma, where the traveling waves have momentum components substantially either all parallel, or all anti-parallel to the confining magnetic field. The injected RF energy is phased to couple to said traveling waves with both a phase velocity component and a wave momentum component in the direction of the plasma traveling wave components. The injected RF energy has a predetermined spectrum selected so that said traveling waves couple to plasma electrons having velocities in a predetermined range .DELTA.. The velocities in the range are substantially greater than the thermal electron velocity of the plasma.