Patents Represented by Attorney Arthur L. Liberman
  • Patent number: 6784273
    Abstract: The invention is directed to a novel biomedical polyurethane based on diisocyanatae linked polyester polymer and diol components, said diol component having a uniform block-length.
    Type: Grant
    Filed: June 19, 2001
    Date of Patent: August 31, 2004
    Assignee: Polyganics B.V.
    Inventors: Coenraad Jan Spaans, Jacqueline Hermina de Groot, Folkert Gerhardus Dekens, Albert Johan Pennings
  • Patent number: 6518054
    Abstract: The present invention provides genes encoding variants of metallo-endopeptidases that have been engineered to be resistant to prolonged boiling while having maintained their enzymatic performance at much lower temperatures. In addition, thermal stability of the metallo-endopeptidases is highly dependent on calcium at concentrations in the mM range. The invention further provides active metallo-endopeptidases variants whose stability depending on calcium concentration can be changed so as to provide metallo-endopeptidases that are calcium dependent or independent. The invention also provides genes that encode boiling-resistant metallo-endopetidases whose stability depending on calcium concentration can be changed. The invention also provides vectors and cells comprising these genes and proteases produced through these genes, vectors and/or cells.
    Type: Grant
    Filed: December 7, 1999
    Date of Patent: February 11, 2003
    Assignee: Rijksuniverstteit Te Groningen
    Inventors: Lambertus Van den Burg, Oene Robert Veltman, Gerard Venema
  • Patent number: 6517759
    Abstract: A fragrance-containing and fragrance-emitting polymeric fiber which optionally contains an antimicrobial agent and a coloring agent is disclosed. A process for producing the fragrance-containing and fragrance-emitting polymeric fiber is also disclosed.
    Type: Grant
    Filed: October 10, 2000
    Date of Patent: February 11, 2003
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Dionisio Ferenc, Elena Susana Novas, Leonardo Oscar D'Ascanio
  • Patent number: 6514933
    Abstract: Described is a process and electronic data processing software program for carrying out same, for the creation of a flavor or fragrance formulation or for the determination of the use of a fragrance or flavor ingredient in a fragrance or flavor formulation or use thereof in or on a perfume composition, perfumed article, cologne, foodstuff, beverage, oral care product (e.g., mouthwash) and/or chewing gum. The process uses apparatus which is a laser light beam transmitter fitted with a light scattering means having attached thereto a titration means.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: February 4, 2003
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Timothy Jay Young, Michael J. Incorvia
  • Patent number: 6511686
    Abstract: Described are novel mixtures of optical isomers of (i) styralyl alcohol (&agr;-phenylethyl alcohol) or (ii) styralyl acetate (&agr;-phenylethyl acetate), fermentation processes for preparing same and organoleptic uses for same as aroma or food flavor ingredients.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: January 28, 2003
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Mohamad I. Farbood, Robert W. Blocker, Joseph Arvizzigno, Ranya Muralidhara
  • Patent number: 6511852
    Abstract: Described is apparatus and a process for collecting for subsequent analysis a volatile composition such as a perfume composition located on the surface and/or in the interstices of a planar pliable porous substrate such as a towel section. A planar surface of the substrate which contains the volatile composition is initially juxtaposed adjacent a solid wall (e.g., glass frit) porous to a nonreactive carrier gas such as air, nitrogen or carbon dioxide, and fully and tightly covers the porous section of the wall. The carrier gas is passed through the porous section of the wall and then through the pliable porous substrate section which is adjacent to the wall; after which the carrier gas contains each component of the volatile composition. The composition-carrier gas mixture is then passed through a trapping substance (e.g., TENAX® a polyphenylene oxide) which entraps the molecules of each component of the volatile composition. The thus-collected volatile composition may be subsequently analyzed (e.g.
    Type: Grant
    Filed: June 18, 1999
    Date of Patent: January 28, 2003
    Assignee: International Flavors & Fragrances Inc.
    Inventor: Walter O. Ledig
  • Patent number: 6506723
    Abstract: Described is a single phase aqueous surfactant-free nontoxic air freshening composition containing 30-70% water, 5-20% of a fragrance, at least 60% of the components of which has a C log10 P≦2.5 and 30-60 weight percent of a mixture of two glycol ether components: (i) dipropylene glycol methyl ether; and (ii) propylene glycol propyl ether or propylene glycol butyl ether. Also described is an air freshener device comprising a vessel for the aforementioned composition, an emanating surface and a wick for supplying the composition to the emanating surface. In another embodiment of the invention is a stain removal wipe, which contains a fragrant aqueous system with low solvent and substantially free of surfactant.
    Type: Grant
    Filed: August 2, 2000
    Date of Patent: January 14, 2003
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Arnoud Van Walsum, Jan-Willem Zacharias Ruizendaal, Richard M. Boden, Andrew John Crossman, Michael John Robert White
  • Patent number: 6500444
    Abstract: Described is a permanently and continuously fragrance-emitting dry or wet wipe laminar fabric article comprising a non-woven fabric lamina having woven therethrough and substantially throughout at least a major portion of the lamina surface at least one continuous fragrance-containing thermoplastic, substantially water-insoluble fiber, which controllably and continuously releases fragrance at least for the time period during which the fabric article is in use. Such fragrance may also have antimicrobial properties. Optionally, one or more antimicrobial substances may also be releasably contained in the fiber containing the fragrance or in a fiber apart therefrom. The fabric article optionally contains additional fragrance and/or antimicrobial agent absorbed in or adsorbed on the non-woven fabric lamina.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: December 31, 2002
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Dionisio Ferenc, Marcos Angelini, Elena Susana Novas, Leonardo Oscar D'Ascanio
  • Patent number: 6495375
    Abstract: Described is apparatus and a process for collection for subsequent analysis a volatile composition such as a perfume composition located on the surface and/or in the interstices of a planar pliable porous substrate such as a towel section. A planar surface of the substrate which contains the volatile composition is initially juxtaposed adjacent a solid wall (e.g., glass frit) porous to a nonreactive carrier gas such as air, nitrogen or carbon dioxide, and fully and tightly covers the porous section of the wall. The carrier gas is passed through the porous section of the wall and then through the pliable porous substrate section which is adjacent to the wall; after which the carrier gas contains each component of the volatile composition. The composition-carrier gas mixture is then passed through a trapping substance (e.g., TENAX®) which entraps the molecules of each component of the volatile composition. The thus-collected volatile composition may subsequently be analyzed (e.g.
    Type: Grant
    Filed: January 16, 2001
    Date of Patent: December 17, 2002
    Assignee: International Flavors & Fragrances Inc.
    Inventor: Walter O. Ledig
  • Patent number: 6482794
    Abstract: A process for producing acetephenone from a source of cinnamic acid is carried out with high amounts of oxygen and sugar in the presence of a bacteria species. Fragrance compositions and foodstuff compositions are augmented and enhanced by the presence of the product compound.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: November 19, 2002
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Mohamad I. Farbood, Augustine Yonghwi Kim, Robert W. Blocker
  • Patent number: 6462015
    Abstract: Described are bicyclic lactones, both fused ring lactones defined according to the generic structure: and spiro lactones defined according to the generic structure: uses thereof in augmenting, enhancing or imparting aromas in or to perfume compositions, perfumed articles, colognes and perfumed polymers; processes for preparing such bicyclic lactones and intermediates therefor. In the structure: Z is one of the moieties: one of R1 or R3 is methyl and the other is hydrogen; and R4, R5, R6, R7, R8 and R9 are hydrogen or nonadjacent C1-C3 alkyl.
    Type: Grant
    Filed: November 10, 2000
    Date of Patent: October 8, 2002
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Richard A. Weiss, Mark A. Sprecker, Marie R. Hanna, Charles E. J. Beck, Harold W. Jackson
  • Patent number: 6444614
    Abstract: Described is the use, [in the absence of (a) fertilizers and (b) Periodic Table Group IIa and greater Group metal cations and chelated metals], of aqueous solutions of the N-substituted aspartic acids, (i) N-(1,2-dicarboxyethyl)aspartic acid [‘IDS’] and (ii) N,N′-1,2-ethanediylbis-aspartic acid [‘EDDS’], ammonium salts, alkali metal salts, ammonium-alkali metal salts and optical isomers thereof in stimulating or regulating the growth of a living, growing plant precursor [germinating seed] or plant [from the ‘seedling stage’ to the ‘late-maturity stage’]. Such use, optionally, is in the presence of aditional adjuvants free from fertilizer as well as Periodic Table Group IIa and greater metal Group cations and chelated metals.
    Type: Grant
    Filed: April 10, 2001
    Date of Patent: September 3, 2002
    Assignee: LidoChem Inc.
    Inventor: Frank W. Dean
  • Patent number: 6426055
    Abstract: Described is a fragrance control release system which is an emulsifier-free, single phase, nonporous, continuous, permeable polymeric film having a substantially uniform thickness of from about 1 up to about 150 microns, having entrapped and dissolved therein molecules of at least one fragrance substance capable of evolving from said film into the environment proximate said film by means of molecular diffusion at a permeation rate of from about 1×10−7 up to about 0.1 mg-mm/cm2-min in a sustained and controlled release manner. Also described is a process for using the aforementioned system for imparting a fragrance into the environment above the unobstructed outer surface of the aforementioned polymer film which is coated on the surface of a solid or semi-solid support, e.g., a solid surface or human epidermis.
    Type: Grant
    Filed: February 2, 2000
    Date of Patent: July 30, 2002
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Adi Shefer, Shmuel David Shefer, John M. Teffenhart
  • Patent number: 6251193
    Abstract: Described are flavored calcium supplement compositions, beverage (e.g., coffee, milk, cocoa and citrus/whey protein), foodstuff, chewing gum and oral care (e.g., toothpaste and mouthwash) compositions and articles comprising flavored calcium supplements, foodstuff, beverage, chewing gum and oral care base compositions and intimately admixed therewith an aroma or taste augmenting, enhancing or imparting quantity and concentration of one or more freeze-dried or spray-dried tastand compositions containing tastands produced from Saccharum officinarum leaves (sugarcane leaves) by means of carrying out one or more physical separation unit operations on a plurality of such leaves, macerates thereof or mixtures of leaves and macerates thereof whereby one or more natural food additives, chewing gum additives or oral care additives is separated and isolated from the remainder of the plurality of leaves, macerates thereof or mixtures of leaves end macerates thereof.
    Type: Grant
    Filed: April 17, 2000
    Date of Patent: June 26, 2001
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Phillip A. Rossy, Richard H. Davidson, Kevin P. Miller, Ira T. Warder, Marvin Schulman, Alan Owen Pittet, Paul L. Bolen, Regina D. Hawn
  • Patent number: 6251463
    Abstract: Described is a process for augmenting, enhancing or imparting an aroma or taste of or to a consumable material which can be: (i) a calcium supplement; (ii) a foodstuff; (iii) a beverage; (iv) a chewing gum; (v) a toothpaste; or (vi) an oral care such as a mouthwash, by adding to the consumable material a tastand composition obtained from Saccharum officinarum leaves (sugarcane leaves) by means of carrying out a sequence of physical separation unit operations on a plurality of such leaves, macerates thereof or mixtures of leaves and macerates thereof, whereby the tastand composition is separated and isolated from the remainder of the plurality of leaves, macerates thereof or mixtures of leaves and macerates thereof; and then spray-drying or freeze-drying the resulting product.
    Type: Grant
    Filed: May 6, 1999
    Date of Patent: June 26, 2001
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Phillip A. Rossy, Richard H. Davidson, Kevin P. Miller, Ira T. Warder, Marvin Schulman, Alan Owen Pittet, Paul L. Bolen, Regina D. Hawn
  • Patent number: 6207274
    Abstract: Described is a fragrance-containing and fragrance-emitting polymeric fiber which optionally contains (i) at least one antimicrobial agent; and (ii) at least one compatible coloring material or color-forming material which is useful in the ascertainment of the exhaustion or substantial reduction of fragrance, produced by either (i) a processing comprising the steps of: (a) co-extruding fragrance and optionally (i) antimicrobial agent and/or (ii) at least one compatible coloring material or color-forming material which is useful for ascertainment of the exhaustion or substantial reduction of fragrance with a thermoplastic polymer to form an extrudate; (b) forming fragrance and (optionally (i) antimicrobial agent and/or (ii) at least one compatible coloring material or color-forming material which is useful for ascertainment of the exhaustion or substantial reduction of fragrance agent)-emitting particles which may or may not be foamed from the extrudate; and (c) extruding a fiber of from about 3 denier up to
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: March 27, 2001
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Dionisio Ferenc, Elena Susana Novas, Leonardo Oscar D'Ascanio
  • Patent number: 6200949
    Abstract: Described is a process for forming controllably releasable fragrance-containing consumable articles, for example, encapsulated fragrances in detergents or fabric softener articles and compositions. The process includes the steps of: (a) forming an aqueous fragrance emulsion, including a modified starch; (b) spray drying or freeze drying the emulsion to form a fragrance-containing powder; and (c) mixing a solid consumable article base (e.g., detergent or fabric softener base) with the fragrance-containing powder. Also described are products produced by means of such processes as well as uses thereof.
    Type: Grant
    Filed: December 21, 1999
    Date of Patent: March 13, 2001
    Assignee: International Flavors and Fragrances Inc.
    Inventors: Henricus Gerardus Maria Reijmer, Adi Shefer
  • Patent number: 6187741
    Abstract: A two phase environmentally friendly fermentation process for producing high yields of &dgr;-decalactone and &dgr;-dodecalactone from the corresponding unsaturated starting materials is carried out under oxidative growth conditions using a saccharomyces species. The resulting products impart, augment and/or enhance the aroma and/or taste of consumable materials including foodstuffs, chewing gums, toothpastes, beverages, fragrance compositions, colognes and perfumed articles such as solid or liquid, anionic, cationic, non-ionic or zwitterionic detergents, fabric softeners, and hair preparations.
    Type: Grant
    Filed: October 4, 1999
    Date of Patent: February 13, 2001
    Assignee: International Flavors & Fragrances Inc.
    Inventors: Mohamad I. Farbood, Laura E. Kizer, James Morris, Gail Harris, Lynda B. McLean
  • Patent number: D474341
    Type: Grant
    Filed: August 30, 2001
    Date of Patent: May 13, 2003
    Assignee: Np
    Inventors: Thomas J. Cantone, Frederick Caputo
  • Patent number: D482284
    Type: Grant
    Filed: February 28, 2003
    Date of Patent: November 18, 2003
    Assignee: NP
    Inventors: Thomas J. Cantone, Frederick Caputo