Abstract: A method of forming a coupled capacitor and transistor is provided. A trench is formed in a semiconductor substrate and an impurity-doped first conductive region is then formed by filling the trench with an impurity-doped first conductive material. The impurity-doped first conductive region is etched back to a first level within the trench. An insulating layer is then formed on a sidewall of the portion of the trench opened by the etching back of the impurity-doped first conductive region and a second conductive region is formed by filling the remainder of the trench with a second conductive material. The insulating layer and the second conductive region are etched back to a second level within the trench and an amorphous silicon layer is formed in the portion of the trench opened by the etching back of the insulating layer and the second conductive region. The undoped amorphous silicon layer is etched back to a third a level within the trench. The undoped amorphous silicon layer is then recrystallized.

Abstract: In a method and an appliance for manufacturing a blister pack having a carboard inlay (blister cardboard pack) a blister pack is provided as an endless tape having the products sealed in blisters. At a unification station a cardboard inlay having recesses for the blisters of the blister pack and having in the direction of conveyance of the blister pack substantially the length of a blister cardboard pack, is placed true-to-size on the blister pack tape, the recesses of the cardboard inlay surrounding the blisters of the blister pack. By a feed pawl, a holding collet and outfeed rollers the blister pack tape is fed to the unification station incrementally and further conveyed incrementally after placement of the cardboard inlay. In a sealing station the cardboard inlay is sealed to the blister pack tape. Subsequently the individual blister cardboard packs are separated from the blister cardboard pack tape in a cutting station.

Abstract: This invention herein describes a method of facilitating the entry of drugs into cells at pharmokinetically useful levels and also a method of targeting drugs to specific organelles within the cell. This lipid/drug conjugate targeting invention embodies an advance over other drug targeting methods because through this method, intracellular drug concentrations may reach levels which are orders of magnitude higher than those achieved otherwise. Furthermore, it refines the drug delivery process by allowing therapeutic agents to be directed to certain intracellular structures. This technology is appropriate for use with antiproliferative drugs, in particular in combination with a multiplicity of other emolients and agents to make up topically-active substances such as salves, for rapid and efficient introduction of antiproliferative agents through the epidermis for treatment of skin diseases such as psoriasis.

Abstract: Calcium phosphate compositions that are particularly useful and unique as orthopedic and dental cements and remineralizers, as well as methods and kits for their use, and the resulting products are disclosed. The compositions comprise tetracalcium phosphate which has been prepared from a mixture with a calcium to phosphorous ratio of less than 2, or prepared and maintained under substantially anhydrous conditions prior to use or, preferably, both. The novel compositions are converted substantially to hydroxyapatite upon setting, are substantially gradually resorbable and replaced by bone when implanted in contact with living bony tissue, and offer distinct advantages in terms of cement strength, setting time and reliability and other properties.

Abstract: A method and an apparatus for electro-optic sampling measurement of electrical signals in integrated circuits, capable of improving the reproducibility of the measurements and calibrating the voltage accurately. The changes of beam intensity of a laser beam reflected from an electro-optic probe is measured by using a low frequency signal of a known voltage level to determine a relationship between the changes of beam intensity and gaps between the electro-optic probe and the integrated circuit, then a proportionality of the change of beam intensity and an absolute voltage level for a desired gap is determined according to the determined relationship. Then, the change of beam of intensity at a desired measurement position with a desired gap is measured by using a high frequency signal and the absolute voltage level of the high frequency signal is determined according to the measured change of beam intensity and the determined proportionality.

Abstract: This invention provides novel methods and reagents for specifically delivering biologically active compounds to phagocytic mammalian cells. The invention also relates to specific uptake of such biologically active compounds by phagocytic cells and delivery of such compounds to specific sites intracellularly. The invention specifically relates to methods of facilitating the entry of antimicrobial drugs and other agents into phagocytic cells and for targeting such compounds to specific organelles within the cell. The invention specifically provides compositions of matter and pharmaceutical embodiments of such compositions comprising conjugates of such antimicrobial drugs and agents covalently linked to particulate carriers generally termed microparticles. In particular embodiments, the antimicrobial drug is covalently linked to a microparticle via an organic linker molecule which is the target of a microorganism-specific protein having enzymatic activity.

Abstract: This invention provides novel methods and reagents for specifically delivering biologically active compounds to phagocytic mammalian cells. The invention also relates to specific uptake of such biologically active compounds by phagocytic cells and delivery of such compounds to specific sites intracellularly. The invention specifically relates to methods of facilitating the entry of antimicrobial drugs and other agents into phagocytic cells and for targeting such compounds to specific organelles within the cell. The invention specifically provides compositions of matter and pharmaceutical embodiments of such compositions comprising conjugates of such antimicrobial drugs and agents covalently linked to particulate carriers generally termed microparticles. In particular embodiments, the antimicrobial drug is covalently linked to a microparticle via an organic linker molecule which is the target of a microorganism-specific protein having enzymatic activity.

Abstract: A flush-closing multi-pane window assembly for a motor vehicle is provided, comprising a frame for mounting in a window recess in the vehicle body, one or more fixed-position panes mounted to the frame and at least one sliding pane mounted to the frame for sliding between an open position and a closed position. In its open position, the sliding pane overlaps a fixed-position pane, but in its closed position is substantially flush therewith. Guide means are provided for guiding the sliding pane as it moves laterally between its open and closed position. The guide means includes fixed members extending from the sliding panes substantially perpendicular to its direction of travel and kick-out means provided by the frame for engaging the fixed members at least during initial lateral movement of the sliding pane from its closed position to its open position.

Abstract: The edge seal mechanism of the present invention may be used in connection with clamshell or other formed sheet metal heat exchanger apparatus of the kind utilized for directing hot flue gases into a defined combustion chamber and into various forms of flue passes for radiation from such heat exchanger such combustion chamber. The improved edge seal structure for a clamshell heat exchanger of the present invention includes a first plate flange portion, around which a second flange plate portion is wrapped to define a channel for disposition of the first plate flange portion therebetween. The seal between the first and second flange portion is further formed and stabilized by means of a lateral bend in the first and second flange portions, with such lateral bend being in the direction of and toward the terminal portion of the second plate flange in order to secure maintenance of the seal between the first and second plate flange portions.

Abstract: A method of and an apparatus for measuring the thickness of the overlay clad of the pressure vessel of a nuclear reactor with good accuracy are disclosed. A magnetic yoke having an appropriate length and cross-sectional area of the magnetic path is placed closely in contact with the surface of the overlay clad of the pressure vessel of the nuclear reactor to form a magnetic path by the magnetic yoke and the pressure vessel of the nuclear reactor, the magnetic yoke is magnetized, the distribution of the magnetic field on or near the surface of the overlay clad in contact with which the magnetic yoke is closely placed is measured and the thickness of the overlay clad of the pressure vessel of the nuclear reactor is identified from the medium value or the half value width of the distribution of the magnetic field thus measured.

Abstract: The combination of zig zag folded tissue stack has separate portions of the tissue defined by lateral perforations. The tissue is a moisturized tissue and is retained in a special rectangular container with the free end of the tissue fitted through a slit which frictionally retains the tissue unless it is manually moved through the slit. The slit is fashioned in a manner which facilitates tearing of the portions of the tissue along the perforations after it is withdrawn through the slit. A cap for the slit is designed to keep the exposed portion of the tissue moist.

Abstract: An electrical assembly includes a housing containing a plurality of electrical components constituted by blocks, each block having a bus-bar and a protruding electrical connection. The electrical connections coincide substantially at the centre of the housing in a stack and are fastened together to directly connect the bus-bars. Preferably, the electrical connections are connected by a screw and bolt fastener passing through aligned apertures of the connections.

Abstract: Apparatus and methods for detecting the location of transverse holes of an intramedullary nail which has been inserted into a long bone and for aligning a surgical drill to the transverse holes. An insert having a light source at its distal end emitting non-ionizing electromagnetic radiation in the visible spectrum or infrared is inserted into the intramedullary nail, such that the light source is placed adjacent to the transverse holes. The light source may be a directional radiation output emitting the radiation in a direction perpendicular to the axis of the intramedullary nail. The light source may alternatively be an isotropic radiation output emitting radiation in all directions. The surgeon detects the transmitted radiation on the surface of the body of the patient and aligns the drill with the emitted radiation. Auxiliary video equipment, such as a camera and video monitor may be used to collect and display the emitted radiation, particularly if light in the infrared portion of the spectrum is used.

Abstract: Apparatus is provided for sewing the crotch portion of a pair of aligned blanks of limp fabric and stacking the sewn blanks which comprises robots (10 and 20) located one on each side of an operator. Each of the robots (10 and 20) is capable of gripping and removing a limp fabric blank from an associated stack of blanks and transporting the blanks to an operator. The robots (10 and 20) have arms (26) capable of axial movement and movement in a vertical plane and additionally capable of rotating about their axes through an angle of 180.degree.. At least one of the robots (10,20) is capable of rotation about a vertical axis, effecting horizontal movement of the arm (26). The apparatus also comprises a sewing head (30) for sewing the crotch portion of the pair of aligned blanks, and a blank support/transfer carriage (41) adjacent the sewing head mounted for horizontal movement in a direction substantially parallel with the direction of sewing.

Abstract: A plastic liner for protecting concrete manhole interior surfaces from corrosion wherein the liner includes provisions for creating a strong mechanical lock between the liner and the interior surfaces. A side of the liner which includes the provisions has a plurality of raised hollow projections with spaced sections. The mechanical lock is created when concrete is poured against the side of the liner with the projections. The concrete at least partially enters the hollow portions and fills spaces between the projection sections. The projections also intersect to enhance the mechanical lock by preventing bulging. Liner sections cover essentially all of the manhole interior surfaces. Forming a liner section by rotationally molding the plastic and cutting gaps into the projections is also disclosed.

Abstract: A computer controlled separator device is disclosed. The computer control system monitors the operation of the separator device and makes any adjustments necessary to maintain optimal operation. An operator may input values representing desired operating parameters and/or desired product characteristics of the separator device. Alternatively, these values may be programmed into the computer control system in accordance with optimal product or system standards. The computer control system monitors the operation of the separator device and makes any adjustments necessary to maintain operation in accordance with the selected or programmed values. Specifically, the computer control system may monitor incoming and outgoing product characteristics, i.e. particle weight, particle density, or particle size; and/or operating parameters, i.e. air flow, vibration speed, side tlit, end raise, feed rate, divider knife position and cutout gate position.

Abstract: This invention relates to a composite of silicon carbide and carbon. This invention also relates to its manufacturing method. An obtained composite is used as heat resistant, wear resistant or chemical resistant materials. The object of this manufacturing method is to form a deep layer of silicon carbide and carbon in the surface of a carbon base by a simple process of causing a silicon containing material to penetrate into and react with the carbon block. Further object of this invention is to produce a compound in whole comprised of silicon carbide and carbon if the carbon block is 20 mm or below in thickness. To this end, according to this forming method a carbon block having a lattice constant c of 6.708 .ANG. to 6.900 .ANG. or below and a density of 1.3 g/cm.sup.3 to 1.7 g/cm.sup.

Abstract: An apparatus for wedging a road barrier panel between opposed flanges of an I-beam post that includes a spring biased arm retained in a recess hole within the back side of the panel.

Abstract: The invention relates to N-alkyl, N-acetylglycosylamines of the formula: ##STR1## wherein R.sub.1 represents the residue of a reducing sugar selected from among glucose, galactose, lactose, or cellobiose;R.sub.2 is an alkyl radical, either linear or branched, comprising from 1 to 24 atoms of carbon, preferably from 8 to 18 atoms of carbon, under the reservation that, when R.sub.1 is a residue of lactose, that R.sub.2 is then different from the nonyl radical. These compounds are useful as surfactants.

Abstract: A device for assisting in the toilet training. The device includes a bowl for receiving human waste as well as an electrical assembly. The electrical assembly includes two pins extending through the bowl, an elastomeric buffer, two contacts interconnected to a resistance sensor, and a melody generator. The buffer provides a solderless electrical connection between the corresponding pins and contacts. When the electrical resistance between the pins decreases, the resistance sensor detects the decrease in resistance between the two pins and contacts and delivers an activation signal to the melody generator.