Abstract: The invention pertains to novel, potent anticonvulsants, analgesics, cognition enhancers and neuroprotectants achieving their action through the antagonism of specific excitatory amino acid neurotransmitter receptors. In particular, the invention is directed to .omega.-[2-(phosphonoalkylenyl)-cycloalkyl]-2-aminoalkanoic acids having general formula: ##STR1## wherein R.sub.1 and R.sub.2 are the same or different and are selected from the group consisting of hydrogen, lower alkyl (C.sub.1 to C.sub.6), alkyl (C.sub.7 to C.sub.12), fatty acid chain (C.sub.13 to C.sub.24), aryl, aralkyl, hydroxyl; the stereoisomers being in their resolved or racemic form; n and m=0,1,2 or 3; z=0,1 or 2; the cycloalkyl ring being replaced with the cycloalkenyl ring; and the pharmaceutically acceptable salts and derivatives thereof.

Abstract: A potent, selective opioid receptor agonist or antagonist exhibiting properties useful for a long-acting analgesic or opiate abuse treatment agent or appetite suppressant having the general formula: ##STR1## wherein R is methyl, cyclopropylmethyl or allyl, and R.sub.1 is an unsubstituted or substituted aryl, aralkyl, heteroaryl, heteroaralkyl or a cycloalkyl group with or without a heteroatom like S,O,N; and the pharmaceutically acceptable salts thereof.

Abstract: A combined phase and frequency modulation device for modulating a data signal in order to generate a plurality of narrow band signals for a communication system is disclosed, characterized by a direct synthesis phase locked loop for generating an output data signal having a selected frequency, a signal divider and phase modulator circuit, and a frequency multiplier for multiplying a modulated signal to produce an output having a desired frequency. The signal divider and phase modulator circuit includes a frequency divider which produces two quadrature related signals from the output data signal. A modulator connected with the frequency divider generates a suppressed carrier double sideband signal from one of the quadrature related signals. A summing device connected with the frequency divider and with the modulator combines the carrier signal with the other quadrature related signal to produce the modulated output signal which is multiplied by the frequency multiplier.

Abstract: Apparatus for crushing cans or the like comprises a conveyor formed from a plurality of endless chains cooperating with a fixed inclined crushing plate converging toward the discharge end of the conveyor. The crushing plate includes an actuator strip-like member hinged to the plate which when depressed engages an electrical switch to operate a drive mechanism for the conveyor. A can deposited into the apparatus depresses the actuator which operates the electrical switch to start the drive mechanism. The can is gripped by the chain conveyor and pulled downward between the conveyor and crushing plate flattening the can. When the flattened can exits the crushing apparatus the actuator is released stopping the drive mechanism. A support housing for the apparatus is provided with an opening for receiving cans which is spaced a distance from the crushing plate and conveyor to reduce the risk of injury.

Abstract: The invention relates to a cooking utensil, for example a cooking pot, wherein the latter has an ion exchanger and/or absorber and/or adsorber and/or filter and/or other device for the extraction of residues of pesticides, herbicides, synthetic fertilizers, hormones and the like from the products to be cooked and prepared, i.e. from the foodstuffs to be prepared, their preparation liquid and/or their vapors during the cooking process. The said harmful substances are to be extracted in this way from the products to be cooked.

Abstract: A tamper resistant animal guard for a drain pipe outlet having self cleaning prongs for preventing the admission of small animals while allowing sticks, leaves and other debris to flow from a drain pipe is provided by the utilization of a plurality of individually rotatable prongs axially disposed on an axle or shaft. A mounting bracket for mounting the axle or shaft is preferably of a flexible material to conform to the inside circumference of the drain pipe while engaging the ends of the axle or shaft which extends substantially across the diameter of the drain pipe.

Abstract: The substitution of the L-Pro at the 7-position of the peptide hormone bradykinin or other substituted analogs of bradykinin with an aromatic amino acid or the D-configuration converts bradykinin agonists into a bradykinin antagonist. The invention further includes additional modifications at other positions within the novel 7-position modified bradykinin antagonists which increase enzyme resistance, antagonist potency and/or specificity of the new bradykinin antagonists. The analogs produced are useful in treating conditions and diseases of the mammal and human body in which an excess of bradykinin or related kinins are produced or injected as by bites into the body.

Abstract: A method and control system for gear cutting machines such as hobbing equipment, shaper cutters and bevel-cutting equipment for achieving greater accuracy, productivity, and gears of increased quality while eliminating error, tedious calculations, labor and product variation is provided by employing a control system and utilizing a method of gear cutting wherein optimum cutter efficiency is maintained by electronically monitoring and controlling cutter input power, cutter shift and workpiece feed or in an alternative embodiment by varying index drive and feed drive in response to inputs measured from the cutter or cutter motor to produce gears approaching the optimum theoretical calculated configuration.

Abstract: The invention pertains to novel, potent anticonvulsants, analgesics and cognition enhancers achieving their action through the antagonism of specific excitatory amino acid neurotransmitter receptors. In particular, the invention is directed to .omega.-[2-phosphonoalkyleneyl)phenyl]-2-aminoalkanoic acids having general formula: ##STR1## Wherein R.sub.1 and R.sub.2 are the same or different and are selected from the group consisting of hydrogen, lower alkyl, halogen, --CH.dbd.CH--CH.dbd.CH.dbd., amino, nitro, trifluoromethyl or cyano; n and m=0, 1, 2, or 3; and the pharmaceutically acceptable salts and derivatives thereof.

Abstract: A transformable circulation tool for reversing the path of drilling fluid at the drill bit without removing the drill string from the borehole annulus is provided by a substantially hollow body having a chamber with external ports disposed between a section of the body having a through passage and a by-pass passage in combination with a diverter mounted on a telescoping member having means for engaging the body during drilling and disengaging the body for rotation of the diverter with respect to each of the passages. A seal is rotatably mounted to the substantially hollow body between the ports to divide the well borehole into an upper conventional flow portion and a lower portion where the flow of the drilling fluid can be reversed upon command from the surface.

Abstract: An adjustable leg for supporting a table top whereby the height can be raised or lowered comprises a metal tube defining the leg within which is mounted a screw threaded rod. A square opening in one side of the wall of the tube exposes the teeth of a gear member which can be rotated and carries a screw thread for cooperation with the rod to raise and lower the table top. Collars on either side of the gear member provide bearing surfaces for axial movement of the rod and for rotational movement of the gear member. The gear member can have two separate axially spaced sets of teeth, one for cooperation with an electric motor drive gear and the other for cooperation with a manually operable ratchet device. The ratchet device and electric motor are alternatives and each of which can be mounted in a housing for clamping around the tubular leg.

Abstract: The invention relates to a steam pressure cooker, which essentially consists of a lower pot and a cover unit sealing the lower pot. The lower pot has a smooth circular pot rim. The cover unit consists of a lower lid and an upper lid. The latter is designed as a sealing element, which engages the lower part of the pot rim by the flanges. As an improvement of this type of pressure cooker, it is proposed that the upper lid contain two half-lids, and that each half-lid be able to rotate about its own axis of rotation essentially parallel to the central axis of the pot (geometrically vertical) relative to the lower lid and lower pot, and further, that the axes of rotation lie eccentric to the pot's central axis and diametrically opposite each other with respect to this axis swivel mechanism rotatably supported concentrically on the lower lid.

Abstract: A universal railroad tie cover of a substantially rectangular configuration is provided which is composed of an elastomer material having one or more openings for receiving one or more elastomer pads for increasing the resiliency of rail fastening systems in railroad track beds with and without ballast to prolong the service life of timber and concrete railroad ties. The universal railroad tie cover has a center section with at least one opening and two side portions for receiving interchangeable specially designed pads some of which may be designed for a particular system and/or for wood or concrete ties to prolong operational life by increasing the resiliency of the rail fastening system. The universal railroad tie cover and particular pads are designed to be manufactured and shipped in a flat configuration which can be cut and installed as a three dimensional cover at the work site to accommodate varying lengths of timber and concrete ties as may be required in special track work.

Abstract: A frying pan is disclosed comprising an upward-facing pan border surrounding a pan bottom to define a pan body, the pan bottom including an upper side to provide a frying surface and a bottom side to provide a stand surface. At least one depositing surface is disposed inside the pan border adjacent to the pan border, with the depositing surface being smaller in area than the frying surface. The depositing surface is raised with respect to the frying surface and spaced, in plan view, outside of the stand surface, with connecting means disposed between the depositing surface and the frying surface which connecting means includes a step.