Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging to the genus Escherichia or Pantoea, which has been modified to attenuate expression of the kefB gene.
Abstract: Converting from a database system to another database system. The conversion process including translating a set of queries for the first database to be used in the second database by determining the query types of the parent and child queries and generating the translated queries according to the type of the query. The type of the query judged as the stored-procedure or the dummy type, irrespective of the existence of a parent query, the function type query after conversion other than the same stored-procedure type query after conversion of the function are generated in all cases. As a result problem is not occurred even when there is a parent.
Abstract: The present invention provides a novel compound having a kininogenase-inhibitory action and its pharmaceutical use. The compounds are represented by the formulas (A), (B), (C), (E) and (H): wherein each symbol is as defined in the specification, or a pharmaceutically acceptable salt thereof.
Abstract: L-glutamic acid is produced by culturing a microorganism in a liquid medium containing L-glutamic acid at a saturation concentration, wherein the microorganism can metabolize a carbon source at a specific pH, and also has an ability to accumulate L-glutamic acid in the medium in an amount which exceeds the saturation concentration of L-glutamic acid, wherein the pH of the medium is controlled so that L-glutamic acid precipitates.
Type:
Grant
Filed:
February 19, 2008
Date of Patent:
February 1, 2011
Assignee:
Ajinomoto Co., Inc.
Inventors:
Yusuke Takahashi, Yasuhiro Tateyama, Masakazu Sato
Abstract: A turbomachine (1), in particular a turbine or compressor, includes a rotor (2) which has at least one moving blade row (4) with a plurality of moving blades (5), and a stator (3) which has at least one guide vane row (6) with a plurality of guide vanes (7), at least in one of the blade or vane rows (4, 6) all the blades or vanes (5, 7) each having a shroud plate (10). In order to simplify the maintenance of the turbo-machine (1), the shroud plates (10) are separate components with respect to the respective blade or vane (5, 7) and are mounted on the respective blade or vane (5, 7), shroud plates (10) adjacent in the circumferential direction (9) being coupled to one another for the transmission of tensile forces in the circumferential direction (9).
Abstract: The present invention provides a key sheet in which adjacent key tops are prevented from moving in conjunction with each other even when intervals between the key tops are designed to be narrow, and which facilitates a depressing operation by eliminating interference between the adjacent key tops. Further, the present invention provides a pushbutton switch using the above-mentioned key sheet. When a central key top is depressed, a portion of a soft sheet positioned between the key top and the key tops therearound is deformed to a large degree. On the other hand, a hard sheet is flexed entirely to a portion extending to a portion directly below the key tops. As a result, a clearance portion between the soft sheet and the hard sheet is formed. Therefore, the left and right key tops do not move in conjunction with each other, thereby making it possible to prevent erroneous input.
Abstract: A rotating electrical machine, especially a turbogenerator, includes a rotor and a stator, which concentrically surrounds the rotor and is terminated at each of the two axial ends by a laminated press plate (14), which is constructed from a stack of individual press plate laminates (30). The electrical properties are improved by providing the press plate laminates (30) at least partially with slits (26) for reducing the eddy current losses.
Abstract: A method and a device for combusting gaseous fuel which contains hydrogen or consists of hydrogen, includes a burner which provides a swirl generator (1) into which liquid fuel is feedable centrally along a burner axis (A), forming a liquid fuel column which is conically formed and which is enveloped by, and mixed through with, a rotating combustion air flow which flows tangentially into the swirl generator (1). The gaseous fuel is fed inside the swirl generator (1) largely axially and/or coaxially to the burner axis (A), forming a fuel flow with a largely spatially defined flow pattern (9) which is maintained inside the burner and bursts open in the region of the burner outlet.
Abstract: A method for producing an L-amino acid is provided which includes culturing in a medium a microorganism of the Enterobacteriaceae family which has an ability to produce an L-amino acid and which has been modified so as to enhance the mannose PTS activity, accumulating the L-amino acid in the medium or in cells, and collecting the L-amino acid from the medium or cells.
Abstract: A method for producing L-glutamic acid by culturing a coryneform bacterium which has L-glutamic acid producing ability and which has been modified so that expression of the fasR gene is enhanced in a medium to produce and accumulate L-glutamic acid in the medium or cells, and collecting L-glutamic acid from the medium or cells.
Abstract: The invention provides an optical phase modulator having a substrate made of an electro-optical material, a signal electrode provided on the substrate and first and second ground electrodes provided on both sides of the signal electrode. The electrodes are provided so that a size of the first gap between the first ground electrode and the signal electrode is smaller than a size of a second gap between the second ground electrode and the signal electrode. Furthermore, an optical waveguide is provided in the first gap as an optical phase modulator and not provided in the second gap. A driving voltage required for the phase adjustments is thereby lowered, the impedance matching is easily made and excellent radio frequency property can be realized.
Abstract: The present invention provides genes that encode the N-acetyl-(R,S)-?-amino acid acylases. The N-acetyl-(R,S)-?-amino acid acylases were isolated and purified from bacterial cells and the nucleotide sequences were determined. A host, such as Escherichia coli, was used to construct a high-expression system for these genes. The N-acetyl-(R)-?-amino acid acylase produced by Burkholderia sp. AJ110349 (FERM BP-10366) includes, for example, the protein having the amino acid sequence shown in SEQ. ID. NO. 8. The gene encoding this enzyme includes, for example, the DNA having the nucleotide sequence as shown in SEQ. ID. NO. 7. The N-acetyl-(S)-?-amino acid acylase produced by Burkholderia sp. AJ110349 (FERM BP-10366) includes, for example, the protein having the amino acid sequence shown in SEQ. ID. NO. 10. The gene encoding this enzyme includes, for example, the DNA having the nucleotide sequence shown inshown in SEQ. ID. NO. 9. The N-acetyl-(R)-?-amino acid acylase produced by Variovorax sp.
Abstract: The present invention provides a method for producing an L-amino acid using a bacterium of the Enterobacteriaceae family, particularly a bacterium belonging the genus Escherichia or Pantoea, wherein said bacterium has attenuated expression of a gene encoding a toxin of a bacterial toxin-antitoxin pair.
Abstract: A novel protein which has an activity to transport hydantoin compounds is described, as well as a recombinant expressing this transporter protein. From Microbacterium liquefaciens strain AJ3912, a novel gene was discovered to encode a protein which is able to transport hydantoin compounds. A recombinant with an excellent ability to uptake hydantoin compounds is obtained by introducing and expressing the novel gene, called mhp, using gene recombination techniques.
Type:
Grant
Filed:
November 28, 2007
Date of Patent:
December 14, 2010
Assignee:
Ajinomoto Co., Ltd.
Inventors:
Shunichi Suzuki, Kenzo Yokozeki, Peter Henderson
Abstract: The present invention provides a new method for producing serine derivatives and their optically-activated derivatives in a convenient manner. In the presence of an enzyme, an L-?-amino acid of formula (I): (in the formula (I), R1 is a hydrocarbon group) is reacted with an aldehyde of formula (II): (in the formula (II), R2 is a hydrocarbon) to produce an L-serine derivative of formula (III). .