Abstract: Valve train with hydraulic lash adjustment in the entire timing train, in which oil is delivered from the oil supply space of the hydraulic valve-lash adjuster (HLA) to the valve rocker arm via a hollow push rod, a choke limiting the oil discharge, the choke being designed in such a way that it seals off the push rod bore at the top when the oil pressure drops, that is to say when the engine is shut off, so that the oil is retained in the push rod bore (12) until—after the engine is started—the choke body (15, 22) opens up the discharge opening again.

Abstract: A process for purifying alicyclic alcohols by distillation, wherein the alicyclic alcohols are distilled in the presence of from 1 to 550 ppm of acidic compounds.

Abstract: An oxygen-depolarized cathode for aqueous hydrochloric acid electrolysis membrane cells is described, the cathode being in contact with the membrane and capable of preventing the release of hydrogen into oxygen even at the highest current densities. Hydrochloric acid may also be of technical grade with a concentration limited to 15%, whereas the operating temperature must not exceed 60° C. The cathode contains a mixture of rhodium sulphide and a metal of the platinum group applied in a single layer or alternatively applied separately in two distinct layers.

Abstract: The invention relates to rapid-curing aqueous coating agents, containing at least one binding agent and at least one water-soluble, quaternary poly(allylamine). Said agents have rapid curing properties and do not discolor during the curing process. Poly(diallyl dialkyl ammonium chlorides) are particularly suitable for use as the water-soluble quaternary poly(allylamine). The inventive coating agents are suitable for use as dyes, rendering agents, primers and wood paints for external applications.

Abstract: The invention concerns proteins of fungal origin having an epoxide hydrolase activity, such as those obtained in essentially pure form by extraction from fungi cells, or by culturing in host cells transformed by a nucleotide sequence coding for said fungal proteins. The invention also concerns the uses thereof, in particular for implementing methods for preparing enantiopure epoxides and/or diols.

Abstract: A discharge duct for discharging pump water from a supply reservoir defined by a first minimum water level and a supply reservoir floor to an operatively higher located delivery reservoir defined by a second minimum water level and the delivery reservoir floor, the discharge duct being defined by an inlet at one end of the discharge duct in communication with the outlet orifice of a conventional pumping device fitted at the supply reservoir; an outlet at the other end of the discharge duct, in the operative configuration of the discharge duct, being below the second minimum water level.

Abstract: A switchable cam follower (1) or a switchable support element of a valve train of an internal combustion engine, said cam follower or support element comprising an outer part (2) which is assembled together with an inner part (4) that is displaceable relative thereto in a direction of cam lift, said inner part (4) comprising, at a parting gap (5) to the outer part (2), two spaced apart or opposing openings (6, 7) for coupling means, each of said openings (6, 7) being aligned, at one cam position, to a further opening (10, 11) for coupling means in the outer part (2), the coupling means being configured and arranged so that, in a coupled state, each coupling means extends beyond the parting gap (5) on one coupling side (12, 13) while simultaneously extending in the opening (10, 6) of the outer and the inner part (2, 4) which in an uncoupled position of the coupling means (14, 15), an axial idle stroke of the coupling means (15) on the one coupling side (12) till coupling is achieved is large and the axial idle

Abstract: The invention proposes an intermediate lever (1) for a variable valve train of an internal combustion engine, said intermediate lever (1) comprising a loading end (2) and a pivoting end (3), a cam contacting surface (4) and a support (5) for a resetting spring (6), the loading end (2) extending on a front end of the intermediate lever (1) and comprising a sliding surface (7) for making contact with a lever-type valve opener, the pivoting end (3) being designed so as to cooperate with eccentric means for affecting a change of position of the intermediate lever (1), and the cam contacting surface (4) being arranged between the loading end (2) and the pivoting end (3), wherein the intermediate lever (1) is made of a thin-walled sheet metal and is manufactured substantially by a punching plus bending method and wherein the support (5) is arranged on an upper side (8, 9) of the intermediate lever (1) in an edge region (10) adjoining the loading end (2) and has a convex portion extending towards the upper side (8,

Abstract: The invention proposes a coupling mechanism (1) for relatively movable elements (2, 3) of a switchable cam follower (4) of a valve train of an internal combustion engine, a high lift being obtainable upon coupling of said elements (2, 3) and a lift smaller than the high lift being obtainable upon uncoupling of said elements (2, 3), a first one (2) of said elements comprising a guide bore (5) for at least one coupling piston (6) which, for achieving coupling, can be displaced partly beyond a parting surface (7) between said elements (2, 3) into an aligned reception (8) of a second one (3) of said elements, wherein upon cam lift and coupling of said elements (2, 3), a contact zone (9) between the piston (6) and the reception (8) is clearly spaced from an edge section (10) of the reception (8) on the parting surface (7). This can be implemented in practice, for instance, through a special “backwards” oriented flattened portion (14) on the piston (6). Material loading on the edge section (10) is thus avoided.

Abstract: Compositions for treating cancer comprising an amount of a camptothecin with a 7-ring ?-hydroxy lactone ring of the formula wherein the substituents are defined as in the specification sufficient to treat cancer.

Abstract: A device for varying valve timing in an internal combustion engine comprises an adjusting mechanism for varying an angle of rotation between a drive pinion (2) and a camshaft (end portion of the camshaft 1), said adjusting mechanism being configured as a wobble transmission. The drive pinion (2) comprises a first front-end gearing (9) and a disk (10) comprises a second front-end gearing (11), which first and second front-end gearings mesh partially with each other, and the number of teeth of said front-end gearings differ from each other by at least one tooth. To reduce the overall dimensions of the device and avoid gearing lash, it is proposed, on the one hand, to connect the disk (10) rotationally fast to the camshaft (1) and on the other hand, to configure the disk (10) in axial direction of the camshaft (1) as a flexible element that can be deformed in axial direction by an adjusting device (thrust plate 17).

Abstract: A process for the preparation of an extract of Ginkgo biloba leaves, comprising i. extraction of the dried fragments of Ginkgo biloba leaves in ethanol containing a maximum of 20% by weight of water; ii. concentration of the extract under reduced pressure in the presence of an aqueous solution of sodium chloride and elimination of the dark oil from the remainder of the clear solution; iii. washing of the residual aqueous solution by liquid-liquid extraction with n-hexane, n-heptane or cyclohexane, iv. liquid-liquid extraction of the aqueous phase washed with ethyl acetate; and v. washing of the ethyl acetate phase obtained in stage iv with a sodium chloride solution followed by evaporation to dryness of the washed ethyl acetate phase and use of the resulting extract to treat cerebral and peripheral vascular disorders and neurodegenerative diseases.

Abstract: In a feed unit of a rod-type actuating element that is arranged in a housing (2) and guided for axial displacement relative to the housing (2), the feed unit further being a drive motor (4) that effects the displacement of the actuating element through a driving device that is rotatably retained in bearings in the housing (2), said driving device being a threaded spindle (1) and a spindle nut (3) surrounding the threaded spindle, wherein the drive motor (4) with its stator (5) and rotor (6) is arranged in the housing (2), and the spindle nut (3) is coaxially arranged in and fixed to a hollow shaft (7) that is surrounded by and fixed to the rotor (6).

Abstract: The invention relates to a process for the synthesis of monochloramine by reaction of an ammonium chloride solution with a sodium hypochlorite solution. The sodium hypochlorite solution is basified beforehand with an inorganic base and the ratio of the concentration of ammonium chloride in the reaction medium to the concentration of sodium hypochlorite in the reaction medium is between 1 and 1.5. This ratio is preferably equal to 1.1.

Abstract: The invention concerns a product inhibiting transduction of G heterotrimeric protein signals combined with another anti-cancer agent, in particular farnesyltransferase inhibitors, taxol or gemcitabin, for simultaneous, separate or prolonged therapeutic use in cancer treatment.

Abstract: The invention is relative to an electrolytic cell comprising electrodes spaced apart from the back-wall by means of ribs, wherein a portion of the contact surface between the electrodes and the ribs is free from constraints in order to permit the complete removal of the electrodes once they have to be replaced by removing only partially the original contact surface, so that positioning of the substitute electrodes is allowed on the residual portion. A method for substituting the electrodes of the cell which leaves the distance between the electrode surface and the back-wall unvaried is also disclosed.

Abstract: A method of treating cholera or travel diarrhea in a patient in need thereof by an effective amount of a compound of the formula wherein the substrates are defined in the specification or its non-toxic, pharmaceutically acceptable salts.

Abstract: The present invention relates to the field of therapeutic chemistry and more especially to the realization of new galenic forms intended to be applied on the skin. More particularly it relates to a topical hormonal composition with a systemic effect for the hormonal treatment of the perimenopause and of the menopause as well as for the treatment of the ovarian hormonal deficiencies in women with amenorrhea, characterized in that it comprises, as active ingredients, a progestogen derived from 19-nor progesterone and estradiol or one of its derivatives, a vehicle which allows the systemic passage of said active ingredients, chosen from the group constituted by a solubilizing agent, an absorption promoting agent, a film-forming agent, a gelling agent and their mixtures, in combination or in a mixture with suitable excipients for the realization of a gelled and/or film-forming pharmaceutical form.

Abstract: A subject of the invention, in all possible isomer forms as well as their mixtures, is the compounds of formula (I): in which either R1: H or CH3 and R2: cyclohexyl substituted by an amine, a (CH2)b-C?N radical or R1 and R2 together with the nitrogen which carries them form a ring with 3, 4 or 5 carbons optionally substituted by an amine R3: hydrogen, methyl or hydroxyl R4: hydrogen or hydroxyl R: represents a linear, branched or cyclic chain T: hydrogen, methyl, CH2CONH2, CH2C?N, a (CH2)2NH2 or (CH2)2Nalk+X? radical, X halogen and alk alkyl Y: hydrogen, hydroxyl, halogen or OSO3H, W: H or OH, Z: H, CH3. The compounds of formula (I) have antifungal properties.

Abstract: A process for the monomethylation of nitrogenous heterocycles having at least one nitrogen atom bonded to a hydrogen atom by reacting the nitrogenous heterocycle with dimethyl carbonate at a temperature of between 100° and 200° C. and a pressure of between 0.93×105 Pa and 1.07×105 Pa while methanol produced during the reaction is distilled off as it is formed.