Abstract: An apparatus for handling sample carrier material is described. The apparatus comprises (a) a punch holder; (b) at least one punch means raisably and lowerably mounted on the holder; (c) a die having an upper and a lower surface, the thickness of the die being less than the punch means lower travel from the die upper surface, the die in functional alignment with the punch means, and the die upper and lower surface in a cutting and delivery position, respectively, of the sample material; and (d) control means to regulate the punch means.

Abstract: A synthetic nonabsorbable surgical suture compound of segmented polyether - ester block copolymers is disclosed.

Abstract: A procedure is disclosed employing the sequential addition of monomers to form a copolymer useful in the manufacture of surgical articles.

Abstract: A single dispensing surgical suture package containing multiple surgical suture strands is disclosed. The package comprises a panel which has a back, a strand cover flap adjacent and connected to one side of the panel by at least one score line, and a foam layer contained on coordinating surfaces of the panel and the flap. The package also comprises an outer panel containing the panel described above.

Abstract: A synthetic nonabsorbable surgical suture compound of segmented polyether--ester block copolymers is disclosed.

Abstract: A procedure is disclosed employing the sequential addition of monomers to form a copolymer useful in the manufacture of surgical articles.

Abstract: A process is disclosed whereby acrylonitrile and diacetone alcohol are reacted in at least 93% sulfuric acid to form a novel intermediate reaction product which is recovered as a crystalline solid, washed with an organic solvent to remove colored oily impurities along with sulfuric acid, and hydrolyzed to produce diacetone acrylamide, a reactive monomer useful for preparing polymeric components of photographic films and adhesives. The intermediate reaction product is identified as 5,6-dihydro-6-hydroxy-4,4,6-trimethyl-2-vinyl-1,3(4H)-oxazine sulfate (1:1).

Abstract: A synthetic nonabsorbable surgical suture compound of segmented polyether-ester block copolymers is disclosed.

Abstract: This disclosure describes a novel process for preparing N-alkylethylenediamines which are useful as intermediates for purifying penicillins. N-alkylethylenediamines are also useful for preparing penicillins and cephalosporins. Specifically, N-ethylethylenediamine is useful for manufacturing piperacillin which is useful as an antibiotic.More particularly, the invention relates to a process for the efficient reaction of an alkyl halide and ethylenediamine and the recovery of anhydrous, ethylenediamine-free N-alkylethylenediamines therefrom.

Abstract: A method suitable for the continuous preparation of acetylsulfaguanidine is described which comprises exposing a thin layer of a concentrated aqueous solution of ammonium acetylsulfanilylcyanamide to microwave radiation until essentially anhydrous ammonium acetylsulfanilylcyanamide is obtained in the form of a glassy, non-crystalline sheet, and converting the dry ammonium acetylsulfanilylcyanamide to acetylsulfaguanidine by heating.

Abstract: A process for the isolation and purification of immunologically active polyribosyl ribitol phosphate (PRP), the capsular polysaccharide of Haemophilus influenzae type b. The PRP has been purified with ethanol, Cetavlon (hexadecyltrimethyl ammonium bromide) and a phosphate containing adsorbent, hydroxylapatite. The contaminants (nucleic acid, proteins and endotoxins) are removed to the minimum level by a treatment with hydroxylapatite. Also described is a process for the preparation of a combined vaccine containing the PRP (prepared as aforementioned) and B. pertussis antigens. The vaccine elicits anti-PRP antibody and antipertussis antibody (as measured by microagglutination) formations in young animals. This sera with anti-PRP antibody exhibits a strong bactericidal activity.

Abstract: An apparatus for separating slack-filled capsules from properly filled capsules having the same surface area comprising:an endless conveyor belt;means for continuously moving the belt on which is contained at least a single layer of capsules;an inclined plane at the terminal end of the belt;a sorting box consisting of a series of fins for orienting the largest cross-sectional area of the capsule profile;a tunnel whose terminal end is adjacent to the box;means for creating laminar air flow through the tunnel;a first tube aligned in about a horizontal position with the tunnel for receiving said slack-filled capsules;a second tube aligned in about a vertical position with the sorting box such that properly filled capsules enter by gravity;such that when the laminar air flow is created through the tunnel, the slack-filled capsules enter the first tube.

Abstract: An eyed needle is described which comprises a pointed end and a butt end, a hole or channel bored into the butt end along the length of the needle, a flexible polymer strand formed into a loop, the ends of the loop placed into the hole or channel, and means of securing the ends of the loop in the needle.

Abstract: A catgut suture package is disclosed which upon opening exposes the looped end of a catgut suture. The suture loop is directly dispensed from the package leaving the label intact within the envelope.

Abstract: The treatment of N-acyl-DL(+)-phenylalanines with D(-)-2-(2,5-dimethylbenzylamino)-1-butanol results in the formation of the D(-)-2-(2,5-dimethylbenzylamino)-1-butanol salt which is obtained as a crystallizate of the N-acyl-L(+)-phenylalanine and from which the desired N-acyl-L(+)-phenylalanine, an intermediate useful for the preparation of artificial sweetening agents, can be recovered.

Abstract: A powder dispenser for inhalating a medicament which comprises a housing containing a converging funnel-shaped mouthpiece; an angular opening on the top of the housing to support a medicament capsule; an impeller; a shaft connected to the impeller at one end; and to a power source at the other end for driving the impeller.The power source can be a battery driven motor, a compressed gas driven power turbine, or a hand power driven differential gear.

Abstract: A surgical suture retaining label for needled and for non-needled multiple sutures is disclosed which permits direct dispensing of the suture. An envelope having a tearing notch and a tear angle guideline across the face of the envelope is also disclosed. When the envelope is torn from the tear notch along the guideline, the label is exposed. The needled and non-needled sutures are held together by a tab. When the tab is pulled, the multiple sutures are directly dispensed from the label.

Abstract: A process is disclosed whereby 5,6-dihydro-6-hydroxy-4,4,6-trimethyl-2-vinyl-1,3(4H)-oxazine sulfate (1:1) is neutralized or alkalized under carefully controlled conditions to produce N-(1,1-dimethyl-3-oxobutyl)acrylamide, a reactive monomer useful for preparing polymeric components of photographic films and adhesives.

Abstract: A process is disclosed for preparing N-(1,1-dimethyl-3-oxobutyl)acrylamide which comprises (1) contacting a dispersion of 5,6-dihydro-6-hydroxy-4,4,6-trimethyl-2-vinyl-1,3,3(4H)-oxazine-3-ium sulfate (1:1) in a water-immiscible organic solvent with a neutralizing or alkalizing amount of gaseous ammonia at a temperature between about 10.degree. C. and 25.degree. C. to form a solution of diacetone acrylamide in said organic solvent and a precipitate of crystalline ammonium sulfate; (2) separating the crystals of ammonium sulfate; (3) cooling the organic mother liquors recovered from step (2) to about -10.degree. C. to 20.degree. C. to crystallize N-(1,1-dimethyl-3-oxobutyl)acrylamide therefrom; and (4) recovering the crystals of N-(1,1-dimethyl-3-oxabutyl) acrylamide, washing the recovered crystals with a cold water-immiscible organic solvent and drying the same.